アブストラクト

評鮮鞠経襲饉議!ヤ
il
似
lNttERNAT10NAL CONFERENCE
1
0N
MEDiCiNEコ SHARING EXPERIENCES:
uSE「QUALITY,AND SAFETYJF
四笹CEユユ:Ell!TY『
封 ―鉢 A u 押
′郷 0 6 体
、
ザ
→
ダ
ン
ヽ
ー
`
―
―
―
ミ
―
Ulaanbaatar,Mongolia
―
.monpharm.mn
ぬ符
I
lNTERNAT10NAL CONFERENCE
ON
"ESSENT:AL MEDiCiNE口
SHARING EXPERIENCES:
ACCESSiB:LITYf uSE「
QUALITYF AND SAFETY″
0●
● ●
● ●
―
す
E
「
Ⅲ算
InternatioRn角
1(】
onttcrerlcc om
“E s s e n t i a l M e d i c iSnhea―
"
r i n g E x p e r i e n c e s : A c c e s s i,bUislei,守
Qualiけ
,and Safe呼
ZC托 脚θ″ZEDCИ
ⅣT
E)istinguished gucsts,Ladies and Gentlemcn,
Thc flrst list ofessential mcdicine uscd ibr ent
treatl■
ofmost co■
lrnon diseascs among W【
ongolians
was rnade in early 90-ies when Mongolia bcgan to transform into market economy.According to this listぅ
thc First Meeting on`1ヾ
ational DrLlg P01icy"discusscd and acccptcd basic principles forthe implementation
of national drug policy.
Since that,National confercncc ofdrug policy、
vas organized 5 tilnes and a list ofcsscntiallncdicinc
、
vas also rcncwcd 5 times.
Onc ofthc priorities ofnational drug policy is to providc thc population
ofい
/1ongolia
and all hospitals
to providc phamaccutical services according and evcn reflccting acccptcd,standardizcd intcrnational
rcqulrcments.
With thc support and assistance ofour partners WHO,印
FPA,LINICEF and■ lany othcr intcrllational
organizations,、
vc havc bccn successn】
llyヽ
V Orking on providing suttcient,qualifled phamaceutical
icc.scn′
And l am vc4/muCh proud to say that this lntcrnational Conferencc on``Esscntial Mcdicinc―
Sharing
Experiences:Accessibilittt Use,Quality,and Safety"is also one ofour successflll prdectS.
We published a pamphlct、vith all thc articles on cssential lnedicinevill
that、
be presented to us
during thc Conference in both ianguagcs English and Mongolian.
The palmphlet consists of 3 topics、
vhich include articlcs on supply,accessibility, quality,security
and clinical phamacy.
I am dceply sure the prcscntations,rnain issues,and results made during the Confcrencc、
vill be
vctt irnportant for thc rcscarch,training and practical rnattcr of national policy of providing WIongolian
vith csscntial drugs.
population and health organizations、
In this maicr,I would like to extend my deepcst gratitudc to WHO Rcprcscntative O
UNICE■ MiniSttt Of HCalth)administration of HSUM and Association of Mongolian Pharmacists and
all other peoplc、
vho put an effortto rnakc this Confcrcncc bc organizcd forthcir
hard、support
vork,kind
and assistance.
Intemationai Confcretlcc on
“E s s e n t i a l M e d i c i n e 口
Sharing Experiences:Accessibility9 Use,Quality9 and SaFety''
Programn for the
International Conference
``Essential Medicine‐
Om
Sharing Experiences:Accessibility,
USe,Quality,and SaFety"
21 August(lMon),2006
09:00-10:00
Registration
10:00o ll:00
0pening Ceremony
Chatrpersoni Proi S,Narantuya Sc.D
Welcome speech by Prot,Ts.Lkhagvasuren Sc.E),
President ofHSuM
Address by Dr.L,Gundalai,
Health Ⅳ
rinister ofい
だOngolia
Address by Dr.R.Hagan,
WttO Representative in Mongolね
Address by Mr.R.Prado,
UNlCEF Representative in Mongolia
Address by Mrs,Delia Barcelona,
LINFPA Representative inヽ4ongolia
11:00‐11:30
11:30-12:00
Key note address by Dre Syed Azhar Syed Suleirnan,
University Sains of Malaytta,
Consultant,WH0
Group photo
COffee break
12:00‐13:00
Thlme l.Accttsibility and Use
Chatrperson:Proi S.Tsetsegmaa PhD
l
‐
12:00‐12:15
Sl-1.Essential Medicioes and Health Priorities
Dr.Syed Azhar Syed Suleiman(Malaysia)
12:15o12:30
Sl-2.The role ofNational Drug P01lcy on the improvement of
12i30‐13:00
13:00‐14:30
accessibiliけ,use and qualiけ Ofmedicine
Mrs,Ch.Mtunkhdelger,MOH
DiscussiOn&cOmments
Lunch
Inlemattonal Conferencc on
“Essential MedicineoSharing Experiences:Accessibility,Use,Quality,attd SaFety"
14:30o16:00
Themel.Accessibilitt and USe
C h a i l p げs o l I D r Syed
.
Azhtt Syed Sulユ mall
14,30‐14:45
14:45o15,00
15:00‐15:15
Sl‐
3 . A c c e s d b i l i t y a l l d s u p p l y o f e s s e net,iedx pmeendeildl■
c e s i e m。mt n ・
RDF
Mぶ 。M.Tuya MDoMP,H,L/NICEF
Sl‐4,Cllallenges tt healhcare malagelnent ttld conttiblltiorl ofpllarmacistt h
developillg colutlSies
Dr,Kaltik Sallayい CID
Sl‐5.PhaHnaceutical edllcation in Mongolia
Academicim,PISott D.Dullgα
dos ScaD,President ofMPA
15,15o16:00
16,00o16:30
Discllss10n&colnm鋼
16t30‐18,00
19t00‐21!00
Vぶ it to llisto拭
ctt places ofUB city
温竹沌()1ぬ
◇lARむ
◇鋸点く
)fl hosted by Proi Ts,Lkllagvasttell Sc,D,
PIへidentofHSUM
低
CofFee break
22 AugLISt(ミ嶺e)ゃ2◇()6
十
9:0い二
Oi30
Cllailpα
1 Themel.Accessibiliけ ,htt USe
solI Acaderniciall,PISof D.DlulgelSdott Sc,D
9,00o9:15
9145‐10:30
Sl‐
6 . A s s e s s m e l l t o f d l e t a ltlts Pianr eM■
ongolian Phalmacelltical System
Proi Ss Tsetsegmaa PhD,HSUM
Sl-7.UNFPA stlategy tt il■
prove access tt rOro血航市e llealth drugs and
COlllll10dities
Mrs.B.Soyoltllya MD.MP.H,UNFPA
Sl‐
8 . T l l e s t t d y o f a c l l toel lpionお
g b yl gdsl ■a l l d c l l e r n i c t t s
Assoc,Pl・
Of P.Bamllyag PhD,HSUM
DiscllssiOn&col■lnellts
10130‐11:00
11,00-13:00
13:00o14:30
Co衛 携 blteak
Visit to dle HOspital
Lllnch
9:15‐
9:30
9:30‐9:45
14:30‐
16:00
Theme2.Qualitt and Safety
Chailpttson:Ml・
s.Carolule Bdsch倒
,AACPA
14:30‐14:45
S2‐1.Solne isslles ofqllality comd ofmedi抗
臨
Asscc,PltOi,D.Tsendeekhllll Sc.D,
14:45o15:00
S2‐
2.Quality cont的
l aald ldardization
sl畑
ofhel・
b medicines uslllg moncclonal
a l l t i b o d y ぃt
a g帆
牡
oactte compolulds
15:15o16:00
比 oi,Dr,Yモ 岨 hitt ShOy価 la(Japallj
S2‐
3 、M o n i t o l S i l l g a t t e lF gS e t td al c■d O n
Assoc.Pl・
On G.α lo打alllts MD,PhD,Mongolemimpex JSC
Discllssloll&COlllmellkR
16:00‐16i30
16:30‐17:30
17i30
CofFee bttak
Poster presentations
Free tilne
15:00o lSi15
t税:ed),2006
interllatioxlal Confcrence on
“Essential Medicine‐
Sharing Experiences:AccessibilityP Use,Quality9 and SaFety"
9:00,10:30
Theme 3.CHnical Pharmacy and PhttrmacOkinetics
ChairpcrsOnt Ch.
Munkhdelger,MloH
9:00-9,15
9:15‐
9:30
9:30-9:45
9:45‐10:30
10130‐
11:00
S3-1.TO renne the prOblenl ofthc HOspital pharrnacy
ヽイ
rs,L.Tserendulam PhD,III CHnical HOspital
S3-2.Ba口 rier in carry out Clinical Pharmacy services:HO、
v to Over come it
D r e S y e d A z h a r S y e d S u l e i m a nイ
(aヽ
laysia)
S3-3,Pharrnacoeconorlical issue OfcOrnlnon used rlledicines in lHcart Failure
Mrs.N.Bayarmaa WISc,1l Clinical Hospital
Discussion&cOmments
Coffee break
11:00‐12:00
Thゃme3.Clinical Pharmacy and Pharmacokinetics
Chairperson:Academician,Proi Do DungerdOtt sCeD
11:00‐
11:15
11:30-12,00
S3-4.Comparative Study on cOst effectiveness Of chemOtherapy for stOmach
cancer patients
Mrs.0.Uranchimeg WrSc.,National Cancer Centre
S3-5,ヽイ
edicine Revie、
v Programs in Australia in the holme and nursing hOme
setting
Mrs.Caroline Bcischer,AACPA(Australia)
DiscussiOn&cOmments
12:00-13:00
Recolnlnendations and closing remark
11:15o ll:30
SIECT10N 2.QUALrTYANI)SAFETY
QUALITYCONTROLAND STANDARDIZAT10N OFIIERB MEDICINES USING
MONOCLONALANTIBODYAGAINST BIOACTIVE COMPOUNDS
YuHhiro Shoyama,IIiroyuH Tanaka
Departrnent ofPharmacognosy,Craduate School of
Pharmaceutical Sciences,Kyushu Uコ iversi守,
3‐1‐
l Maidashi,IIigashi‐ku,Fukuoka,JaPan
Although the immunoassay system using monoclonal antibodies is now indispensable for various
investigations,it is not so famlliar for naturally occurring bioactive compounds having small lnolecular
、
veight.Rcccntly rapid,simple,highly scnsitivc and reproducible assay systems are required fbr quantitative
and/or qualitative analytical techniqucs in herb rnedicines,phytomedicines and anilnals in a ng and pg
scale.
In our ongoing study on the medicinal plant proJect,we have produced monoclonal antibodies against
forskolin,solarnargine,opium alkaloids,rnarihuana compounds,glycyHhizin,crocin,ginsenoside Rbl,
R g l a n d R e , s e I I n o s i d e A a n d B , s a i k o s a p o n i n a , p a e o n i n o r i n , b c r,baenddn ea papnldi esdo toh■
em for
immllnoattnity chromatography,castem bloting,immunocytolocalization,and scFV fo..1lation and its
use for brecding.In this conference we focus newly established(1)eastern blotting and
immunocytolocalization and(2)llnlnunOafflnity concentration.
(1)Eastem blo性ing of saponins
The bloted PVDF membrane from TLC plate developed by solvent systeln was treated with Na104
and then BSA.This reaction enhanced the flxing of saponin via saponin―BSA conJugate on the PV】 DF
membrane.The PVDF rnembrane、
vas treated wlth rnonoclonal antibody against saponin,then secondary
monoclonal antibody labelcd with enzyme,and flnally substrate.The staining is spcciflc and high sensitive
compared to i「
LC stained with sullttric acid.
(2)ImmunOafrlnity concentration of bioactive compound
lmmuncafflnity column cottugated with monoclonal antibody which is preparc
COttugatiOnwithgelcanbeused forimmunoconcenttationresultinginhighsensitivequ
oftarget compoundメ
and rnakes it possiblc to isolate the target
compound
by one―
step
puriflcation.
儀 乾献 啄ォル ☆
陶 晦 が ゎえ竹
・曲
甲・
● ● ●
● ● ●
ン︼
APPRECmWON
を
O greatry比 。r20r
‐
0え 協 筋 初 膨解 物
D丘物 ′
拘r your yaruabe a盟 どremarkabrc Presenを aをfO回
の
物 沈
夕
σク″掬
〃 ″冴
g物 湯
″ク
σ
あ″″わ ″筋 均
″θ
r品
筋 ″
ゲ
あ 形
解 像れ 曲
舛
″母ガ
留
″務
7 4 i Z 3 ナ励 肋 夕切″ θ
ne mternaが onar COnttreコ ce
aをす
(除 scntFar随
前cJine_Shaガng exPeガ encesr Accessfbゴ fry,
L/se,9warfけ,コどsarety>
ec oF
Cttafrman oゴ Organizing Commfを を
r足を
crraす onar COnFerer2Ce, Presfdenを of
Proi Ts.軸
agyasLIrer2
Augusを 22,2θ θ6
ar,MongO】 均
明aanわaaを
、