Invitation to Seminar Talk Epithelial morphogenesis: Creating sheaths and ridges in zebrafish skin cells Alvaro Sagasti Department of MCD Biology, UCLA Host: Carl-Philipp Heisenberg During development many cells form membrane specializations that give them their unique shapes and properties. To identify mechanisms that sculpt cell membranes, we are studying two cellular morphogenetic processes in the zebrafish skin, a bilayered epithelial tissue. Cells in the outer skin layer form regularly spaced, swirling wrinkles on their apical surface called microridges; cells in the inner layer wrap their apical membranes around sensory axons to ensheath them. With live imaging we have broken down each morphogenetic process into discrete steps. Using molecular and genetic manipulations we have identified specific proteins and molecular processes that mediate each of those steps. Our studies reveal how cell membranes and the underlying cytoskeleton are arranged to create elaborately patterned structures within a single cell. Monday, June 13, 2016, 4:00pm Experimental Biology Room, Bertalanffy Foundation Building, 2nd Floor This invitation is valid as a ticket for the IST Shuttle from and to Heiligenstadt Station. Please find a schedule of the IST Shuttle on our webpage (note that the IST Shuttle times are highlighted in dark green): http://ist.ac.at/fileadmin/user_upload/pdfs/IST_shuttle_bus.pdf The IST Shuttle bus is marked IST Shuttle (#242) and has the Institute Logo printed on the side. Institute of Science and Technology Austria | Am Campus 1 | 3400 Klosterneuburg www.ist.ac.at
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