2nd International workshop on Cancer Genetic & Cytogenetic Diagnostics March 26 to March 28, 2014 Radboud university medical center, Nijmegen, The Netherlands The workshop will focus on all aspects concerning cancer genetics and cancer cytogenetics in a diagnostic setting. Technical aspects such as conventional karyotyping, methods and principles of fluorescence in situ hybridization (FISH) and new methods in cytogenetics such as micro-array genomic profiling, MLPA and next generation sequencing will be discussed. During the workshop interpretation of cytogenetic and genetic data in relation with cancer (onco-hematology and solid tumors) and predisposition to cancer will be presented. Practical exercises will be offered with the ISCN 2013 system for chromosome aberrations and with cytogenetic and genomic databases. Furthermore students will practice with data obtained by karyotyping, FISH and micro-array and translation of these data in a report. Participants will have the opportunity to present their own observations and cytogenetic findings which are difficult to interpret. INVITED SPEAKERS Torsten Haferlach, Munich Bertil Johansson, Lund Christine Harrison, Newcastle Philip Kluin, Groningen Jacqueline Schoumans, Lausanne Ros Hastings, Oxford Annet Simons, Nijmegen Brian Walker, Sutton Marjolijn Jongmans, Nijmegen Bauke Ylstra, Amsterdam Jon Strefford, Southampton Gerwin Huls, Nijmegen Ad Geurts van Kessel, Nijmegen Bert van der Reijden, Nijmegen ORGANISING COMMITTEE Marian Stevens-Kroef, Nijmegen Eva van den Berg, Groningen Berna Beverloo, Rotterdam INFORMATION AND REGISTRATION The fee of €500,00 includes the drinks and lunches during the workshop , all course materials and one conference dinner. The organising committee will offer two grants, which includes the registration fee but excludes travel expenses and accommodation. The grants will be awarded to participants who are most in need of financial support. Further information and registration: www.paoheyendael.nl/cancergenetics2014 Program March 26, 2014 9:00 Welcome 9:10 Chronic Myelogenous Leukemia 10:00 Quality assessment 10:50 BREAK 11:10 Karyotyping 12:00 FISH 12:50 LUNCH 13:50 Practical exercises in data analysis 16:00 BREAK 16:20 Array based genomic profiling 17:10 Cytogenetic nomenclature: ISCN 2013 18:00 End and Conference dinner March 27, 2014 9:00 Molecular diagnostics (including MLPA, QPCR) 9:50 New Technologies in tumor genetics (NGS) 10:40 BREAK 11:00 Integration of diagnostic analysis 11:50 Myelodysplastic syndromes and Myeloproliferative neoplasms 12:40 LUNCH 13:40 Acute Myeloid Leukemia 14:30 Acute Lymphoblastic leukemia 15:20 BREAK 15:40 Atlas of Genetics and Cytogenetics in Oncology and Haematology 16:00 Practical exercises with ISCN, databases and text books 18:00 End March 28, 2014 9:00 Plasma Cell Neoplasms 9:50 Chronic Lymphocytic Leukemia 10:40 BREAK 11:00 Lymphoma 11:50 Solid tumor I (karyotyping) 12:40 LUNCH 13:40 Solid tumor II (molecular) 14:30 Genetic predispostion of cancer and cancer prone disease 15:20 BREAK 15:40 Cases brought by participants 17:00 End Ad Geurts van Kessel Ros Hastings Ros Hastings Berna Beverloo Jacqueline Schoumans Annet Simons Bert van der Reijden Torsten Haferlach Torsten Haferlach Gerwin Huls Bertil Johansson Christine Harrison Jean-Loup Huret Brian Walker Jon Strefford Philip Kluin Ad Geurts van Kessel Bauke Ylstra Marjolijn Jongmans