㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)㧗㱋⪅ᢚ࠺ࡘ㸧 ᩥ⊩ Shahidi M, et al. Laughter Yoga versus group exercise program in elderly depressed women: a randomized controlled trial International Journal of Geriatric Psychiatry.2011, 26: 322-27.Pubmed ID:20848578 ┠ⓗ 㧗㱋ዪᛶ࡟࠾ࡅࡿ࢝ࢱࣜ࢔ᘧ➗࠸ࣚ࢞ࡢᢚ࠺ࡘపῶຠᯝ࡜ே⏕‶㊊ᗘྥୖຠᯝࢆࠊࢢ࣮ࣝ ࣉ࣭࢚ࢡࢧ࢖ࢧ࢖ࢬ⒪ἲ࡜ẚ㍑ࡍࡿ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ ࢸ࣊ࣛࣥᕷ➨ 13 ༊ෆ࡟ᡤᅾࡍࡿᩥ໬ࢥ࣑ࣗࢽࢸ࢕ࢭࣥࢱ࣮ ཧຍ⪅ ྠᩥ໬ࢥ࣑ࣗࢽࢸ࢕ࢭࣥࢱ࣮࡟ᡤᒓࡍࡿࠊ࠺ࡘഴྥࢆᣢࡘዪᛶ 70 ྡ(60-80 ṓ) ௓ධ ࢝ࢱࣜ࢔ᘧ➗࠸ࣚ࢞ ᅇࡢࡳ $UP➗࠸ࣚ࢞⩌ ྡ ࢭࢵࢩࣙࣥ࡟ࡼࡾᵓᡂ $UP࢚ࢡࢧࢧ࢖ࢬ⩌ ྡ ศࡢ᭷㓟⣲㐠ື࡜ ศࡢఇ᠁ $UPࢥࣥࢺ࣮ࣟࣝ⩌ ఱࡶࡋ࡞࠸⩌ ྡ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ Yesavage Geriatric depression scale (Yesavage ⪁ᖺ࠺ࡘ⑓ᑻᗘ) Diener life satisfaction scale (Diener ே⏕‶㊊ࢫࢣ࣮ࣝࠊLSS) ௓ධ๓ᚋࡢ㸰ᅇࠊ ᐃࠋ ୺࡞⤖ᯝ ⪁ᖺ࠺ࡘ⑓ᑻᗘᚓⅬ㸸➗࠸ࣚ࢞⩌ࠊ࢚ࢡࢧࢧ࢖ࢬ⩌ࡣࠊࢥࣥࢺ࣮ࣟࣝ࡟ẚ࡭࡚᭷ព࡞ᨵၿ ࡀぢࡽࢀࡓ㸦➗࠸ࣚ࢞⩌(P<0.01)ࠊ࢚ࢡࢧࢧ࢖ࢬ⩌(P<0.1)㸧ࡀࠊ➗࠸ࣚ࢞⩌࡜࢚ࢡࢧࢧ࢖ ࢬ⩌࡜ࡢ㛫࡛ࡣᨵၿᗘྜ࠸࡟᭷ព࡞ᕪࡣ࡞࠿ࡗࡓ ே⏕‶㊊ࢫࢣ࣮ࣝ㸸➗࠸ࣚ࢞⩌ࡢࡳࢥࣥࢺ࣮ࣟࣝ࡟ẚ࡭࡚᭷ព࡞ᨵၿࡀぢࡽࢀࡓ(P<.0.01) ࡇࢀࡽࡢ㡯┠࡛ࠊࣚ࢞⩌࡜࢚ࢡࢧࢧ࢖ࢬ⩌࡜ࡢ㛫࡟ࡣᕪࡣ࡞࠿ࡗࡓࠋ ⤖ㄽ ➗࠸ࣚ࢞ࡣࠊᢚ࠺ࡘഴྥࡢ㧗㱋ዪᛶ࡟࡜ࡗ࡚ࠊᑡ࡞ࡃ࡜ࡶࢢ࣮ࣝࣉ㐠ືࣉࣟࢢ࣒ࣛ࡜ྠᵝ ࡟㨚ࡸே⏕ࡢ‶㊊ឤࡢᨵၿ࡟ຠᯝࡀ࠶ࡿࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ⩌࡟࠾࠸࡚ ྡࡀࢻࣟࢵࣉ࢔࢘ࢺ ⌮⏤ࡣ୙᫂ ࣚ࢞ࡢヲ⣽ ᴦࡋ࠸ฟ᮶஦㸦ᅜࡢ⾜஦ࡸ᐀ᩍⓗ൤ᘧ࡞࡝㸧࡟ࡘ࠸࡚▷ࡃヰࡍ 2.యࢆື࠿ࡍ ᡭ ࢆࡓࡓࡁࠊྠ᫬࡟⡆༢࡞ࢳࣕࣥࢶ(౛㸸࣍ࠊ࣍ࠊࣁࣁࣁ)ࢆຍ࠼ࡿ 4. ᚰ㌟࡜ࡶ࡟ࣜࣛࢵࢡ ࢫࢆࡶࡓࡽࡍ῝࿧྾ࢆ஺࠼ࠕ⚾ࡣୡ⏺୍࡛␒ᖾࡏ⪅ࡔࠖ࡜ྉࡧࠊᡭࢆ྇ࡁ௰㛫ࢆぢ࡚➗࠺ࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ᢚ࠺ࡘࠊே⏕‶㊊ᗘࡢᨵၿࡣࠊձࠕ➗࠺ࠖ࡜࠸࠺⾜Ⅽࡀࠊ➽⫗ࡢ⦆࿴ࠊච␿ࠊ࣍ࣝࣔࣥࠊ ᚰ⌮㠃࠿ࡽᚰ㌟⑕≧ࢆᨵၿࡍࡿຠᯝ㸦➗࠸ࣚ࢞๰ጞ⪅࢝ࢱࣜ࢔ࡣࠕ➗࠺ࠖ⌮⏤ࡢ᭷↓࡟࠿ ࠿ࢃࡽࡎᨵၿຠᯝࡀ࠶ࡿࡇ࡜ࢆᙉㄪ㸧ࠊղ➗࠸ࣚ࢞࡟࠾ࡅࡿࣚ࢞ㅖᢏἲ㸦య᧯ࠊ࿧྾ἲ㸧 ࡢຠᯝ࡟ࡼࡾ⏕ࡌࡓ࡜⪃࠼ࡽࢀࡿࠋࠕ➗࠺ࠖ࡜࠸࠺⾜Ⅽࡣࠊேࠎ࡟ᖾ⚟ឤࡸᎰࡋ࠸ឤ᝟ࢆ ࡶࡓࡽࡍ࡜⪃࠼ࡿࠋࡑࡋ࡚ࠊ࢝ࢱࣜ࢔ࡀᣦ᦬ࡍࡿࡼ࠺࡟ࠊࣜࢬ࣒ࡼࡃኌࢆฟࡋ࡚➗࠺ࡇ࡜ ࡛ࡲࡓࠊ⫵ࡸ⬚➽ࠊ⭡➽࡟ാࡁ࠿ࡅ࡞ࡀࡽ࿧྾ࡀฟ᮶ࡿ࡜⪃࠼ࡽࢀࡿࠋࡇࡢࡓࡵ➗࠸ࣚ࢞ ࡜࢚ࢡࢧࢧ࢖ࢬࢆ⾜࠺ࡇ࡜࡟ࡼࡾࠊ⫯ᐃⓗ࡞ᚰ⌮స⏝ࡀ⏕ࡌࠊࡲࡓ㌟య㠃࡟ࡶຠᯝࡀ࠶ࡿ ࡜⪃࠼ࡿࠋ $EVWUDFWRU ࡢ᥎ዡᗘ 㧗㱋ዪᛶ࡟ᑐࡍࡿࠊᢚ࠺ࡘపῶຠᯝ࡜ே⏕‶㊊ᗘྥୖຠᯝࡢࡓࡵ࡟ࠊࣚ࢞ࢆ່ࡵࡿ $EVWUDFWRUDQG'DWH ᐑᓮ ┿ᘪ ᒸ Ꮥ࿴ 2013.11.1 − 86 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)㧗㱋⪅ᢚ࠺ࡘࠊ୙╀㸧 ᩥ⊩ Chen KM, Chen MH, Chao HC, Hung HM, Lin HS, Li CH: Sleep quality, depression state, and health status of older adults after silver yoga exercises: Cluster randomized trial. Int J Nurs Stud 2009;46:154-163. Pubmed ID:18947826 ┠ⓗ 㧗㱋ᡂே࡟ᑐࡍࡿ㸴࢝᭶ࡢࢩࣝࣂ࣮ࣚ࢞㐠ືࡢຠᯝࠊ≉࡟╧╀ࡢ㉁ࠊᢚ࠺ࡘࠊ೺ᗣ≧ែ࡟ ᑐࡍࡿ⮬ᕫㄆ㆑ࠊࢆㄪ࡭ࡿ ◊✲ࢹࢨ࢖ࣥ &OXVWHUUDQGRPL]HGWULDO ࢭࢵࢸ࢕ࣥࢢ ࢝ᡤࡢࢩࢽ࢔࢔ࢡࢸ࢕ࣈࢸ࢕ࢭࣥࢱ࣮ ཧຍ⪅ 㻢㻜 ṓ௨ୖ䛾䝁䝭䝳䝙䝔䜱䞊ᒃఫ⪅䛷䝉䝹䝣䜿䜰䛜⊂❧䚸䜒䛧䛟䛿㍍ᗘ౫Ꮡ䛾㧗㱋⪅㻔ᖹᆒ 㻢㻥 ṓ㻕㻌 ௓ධ ࢩࣝࣂ࣮ࣚ࢞ࣉࣟࢢ࣒ࣛ ᅇ ศ㐌 ᅇ ࣨ᭶㛫 $UP௓ධ⩌ ࣚ࢞⩌ ྡ $UPࢥࣥࢺ࣮ࣟࣝ⩌ ᚅᶵ⩌ ྡ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ Pittsburgh Sleep Quality Index (PSQIࠊ╧╀)ࠊTaiwanese Depression Questionnaire (TDQࠊ࠺ࡘ)ࠊ SF-12 Healthy Survey㸦೺ᗣ≧ែ࡟㛵ࡍࡿ⮬ᕫㄆ㆑㸧ࢆ௓ධ๓ࠊ௓ධ㛤ጞ3ࣨ᭶ᚋࠊ6ࣨ᭶ᚋ ࡟ホ౯ࠋ ୺࡞⤖ᯝ ⩌㛫ẚ㍑࡛ࡣࠊ3ࣨ᭶ᚋࠊ௓ධ⩌ࡢ᪉ࡀࢥࣥࢺ࣮ࣟࣝ⩌ࡼࡾࠊPSQI࡟ࡼࡿ⮬ぬⓗ࡞╧╀ࡢ ㉁ࡀࡍࡄࢀࠊ᪥୰ࡢᶵ⬟୙඲ࡀప࠿ࡗࡓࠋ㌟యⓗࠊ⢭⚄ⓗ೺ᗣㄆ▱ᚓⅬࡀ㧗ࡃࠊ࠺ࡘᚓⅬ ࡀప࠿ࡗࡓࡀࠊ╧╀₯᫬ࡣ௓ධ⩌ࠊࢥࣥࢺ࣮ࣟࣝ⩌࡛ᕪࡣ࡞࠿ࡗࡓࠋ6ࣨ᭶ᚋࡣࠊୖグࡣ ࡍ࡭࡚௓ධ⩌࡛ࡍࡄࢀ࡚࠸ࡓ㸦╧╀₯᫬ࡶࢥࣥࢺ࣮ࣟࣝ⩌ࡼࡾ▷ࡃ࡞ࡗࡓ㸧 ࠋ 㸦࠸ࡎࢀࡶ p<0.05㸧 ⤖ㄽ 㸴࢝᭶ࢩࣝࣂ࣮ࣚ࢞ࢆ⾜࡞ࡗࡓ⩌࡛ࡣࠊ㧗㱋⪅ࡢ࣓ࣥࢱࣝ࣊ࣝࢫᣦᶆࡢ࡯࡜ࢇ࡝ࡀࢥࣥࢺ ࣮ࣟࣝ⩌ࡼࡾୖᅇࡗࡓࠋ㧗㱋⪅ࡢ࣓ࣥࢱࣝ࣊ࣝࢫྥୖຠᯝࡢ࡯࡜ࢇ࡝ࡣࠊ㸱ࣨ᭶ᚋ࡛ᚓࡽ ࢀࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ᭷ᐖ஦㇟࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ୧⩌࡛ 㸣 ⌮⏤ࡣ࣮࢜ࢺࣂ࢖஦ᨾࡸ㌿ᒃ ࣚ࢞ࡢヲ⣽ ࢩࣝࣂ࣮ࣚ࢞㐠ືࣉࣟࢢ࣒ࣛࡣ&KHQ࡟ࡼࡗ࡚㧗㱋⪅ࠊᰂ㌾ᛶࡀపୗࡋࡓࡶࡢ࡟࠶ ࢃࡏࠊ㛤Ⓨࡉࢀࡓࣉࣟࢢ࣒ࣛࠋ㸲ࡘࡢࣇ࢙࣮ࢬ࠿ࡽ࡞ࡾࠊ࣮࣒࢘࢜࢔ࢵࣉ㸦ศࠊ㌟ యࢆࡸࢃࡽࡆࡿ㸶ࡘࡢ࣏࣮ࢬ㸧 ࠊࣁࢱ࣮ࣚ࢞㸦ศࠊ㧗㱋⪅ࡢ㌟య⬟ຊࠊ⪏ᛶࢆ≉࡟⪃ ៖ࡋࡓࠊྍືᇦ࡜₞㐍ⓗ➽ᘱ⦆ࢆࡲࡍࡓࡵࡢࠊࢆ㸵ࡘࡢࡺࡿࡸ࠿࡞ࢫࢺࣞࢵࢳࡍࡿ࣏࣮ ࢬ㸧 ࠊࣜࣛࢡࢮ࣮ࢩࣙࣥ㸦ศࠊ㌟యࢆࡸࡍࡵࡿ㸱ࡘࡢάືࠊㄏᑟࡉࢀࡓ࢖࣓࣮ࢪ ▂᝿ࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ࢩࣝࣂ࣮ࣚ࢞ࡣ㧗㱋⪅⏝࡟㛤Ⓨࡉࢀࡓࡶࡢࡢࡼ࠺࡛࠶ࡿࡀࠊᐇ᪋࡟࠶ࡓࡾࠊࣚ࢞࢖ࣥࢫࢺ ࣛࢡࢱ࣮ࡣࠊࡑࢀࡒࢀࡢ࣏࣮ࢬࡣ✜ࡸ࠿࡟ࠊ㐺ᗘ࡟⾜࡞࠺ᵝᙉㄪࡋࠊ࣏࣮ࢬ୰ࡣ࠿ࡽࡔࢆ ᐖࡍࡿ࡯࡝ࡣᘬࡁᘏࡤࡉ࡞࠸ࡼ࠺࡟࡜ࠊᖖ࡟ὀពࡋ࡚⾜࡞ࡗࡓࠊ࡜グ㍕ࡉࢀ࡚࠾ࡾࠊࡑࢀ ࡀ㧗㱋⪅ࡀᑐ㇟࡛࠶ࡿ࡟ࡶ࠿࠿ࢃࡽࡎࠊ᭷ᐖ஦㇟ࡀ඲ࡃッ࠼ࡽࢀ࡞࠿ࡗࡓ⌮⏤࡛࠶ࢁ࠺ࠋ $EVWUDFWRU ࡢ᥎ዡᗘ 㧗㱋⪅ࡢ࣓ࣥࢱࣝ࣊ࣝࢫྥୖࡢࡓࡵ࡟ࢩࣝࣂ࣮ࣚ࢞ࢆ່ࡵࡿ $EVWUDFWRUDQG'DWH ᒸᏕ࿴ − 87 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)㧗㱋⪅ᢚ࠺ࡘ㸧 ᩥ⊩ Krishnamurthy MN et al. Assessing Depression Following Two Ancient Indian Interventions: Effects of Yoga and Ayurveda on Older Adults in a Residential Home. Journal of Gerontological Nursing; 2007; 17-23. Pubmed ID:17310659 ┠ⓗ ᪋タධᡤ㧗㱋⪅࡟࠾࠸࡚ࠊ ࣨ᭶㛫ࡢ࣭ࣚ࢞ࣉࣟࢢ࣒ࣛ࡜࢔࣮ࣦ࢙࣮ࣘࣝࢲ⏕⸆〇๣ࡢᢚ ࠺ࡘᨵၿຠᯝࢆ᳨ウࡍࡿ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ ࢖ࣥࢻࠊ%DQJDORUH ࡟࠾ࡅࡿ㧗㱋⪅ධᡤ᪋タ ཧຍ⪅ ᪋タ࣮࣒࣍ࡢ ṓ௨ୖ ྡ ௓ධ $UP௓ධ⩌ ࣚ࢞⩌ ྡ 69<$6$ ࠺ࡘ⑓ࣉࣟࢢ࣒ࣛ ᅇ ศ㐌 ᪥ 㐌㛫 $UP௓ධ⩌ ࢔࣮ࣦ࢙࣮ࣘࣝࢲ⩌ ྡ ⏕⸆ࣛࢧࣖࢼ࢝ࣝࣃࢆ ᪥ ᅇᦤྲྀࠋ $UPࢥࣥࢺ࣮ࣟࣝ⩌ ᚅᶵ⩌ ྡ ௓ධᚋ࡟ࣚ࢞࠿࢔࣮ࣦ࢙࣮ࣘࣝࢲᐇ᪋ྍ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1. The 15-item Geriatric Depression Scale (GDS, 15 㡯┠ࡢ⪁ᖺᮇ࠺ࡘᑻᗘ) ௓ධ๓ࠊ㸱ࣨ᭶ᚋࠊ㸴ࣨ᭶ᚋࡢ㸱ᅇࠊ ᐃࠋ ୺࡞⤖ᯝ ࣚ࢞⩌ࡣࠊ࣮࣋ࢫࣛ࢖ࣥ࡜ẚ㍑ࡋ࡚ 3 ࣨ᭶(p <0 .001)ࠊ࠾ࡼࡧ 6 ࣨ᭶ (p <0 .001)࡟࠺ࡘ⑕ ≧ᚓⅬ(GDS)ࡀ᭷ព࡟ῶᑡࡋࡓࡀࠊ࢔࣮ࣦ࢙࣮ࣘࣝࢲ⩌࡜ᚅᶵ⩌࡛ࡣ᭷ព࡞ኚ໬ࡣㄆࡵࡽ ࢀ࡞࠿ࡗࡓࠋ ⤖ㄽ ㌟యⓗカ⦎࡟ࠊ⢭⚄ⓗࠊဴᏛⓗ࡞ほⅬࢆྵࡵࡓࣚ࢞ࡢ⤫ྜⓗ࢔ࣉ࣮ࣟࢳࡣࠊ᪋タ࡟࠸ࡿ㧗㱋⪅࡟࡜ࡗ࡚᭷⏝࡛࠶ࡿࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࣚ࢞⩌㸣 ࢔࣮ࣦ࢙࣮ࣘࣝࢲ⩌㸣 ⌮⏤⏕⸆〇๣ PO ࢆẖ᪥ ᅇᦤྲྀ ࡍࡿ஦࠿ࡽ‶⭡࡜࡞ࡾࠊ㣧ࡳࡓ࠸ࢥ࣮ࣄ࣮ࢆᴦࡋࡵ࡞ࡃ࡞ࡿ ࢥࣥࢺ࣮ࣟࣝ⩌㸣 ࣚ࢞ࡢヲ⣽ ࣈ࣮ࣜࢪࣥࢢ㺃࢚ࢡࢧࢧ࢖ࢬศࠊ࣮ࣝࢬࢽࣥࢢ㺃࢚ࢡࢧࢧ࢖ࢬศࠊయ఩ἲ㸦❧఩ࠊ ௮⮩఩ࠊ⭡⮩఩ࠊᗙ఩ࢆศ㸧ࠊ࿧྾ἲศࠊࣚ࢞࡟ᇶ࡙ࡁㄏᑟࡍࡿࣜࣛࢡࢭ࣮ࢩࣙࣥ ศࠊ⪷ḷศ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ 㧗㱋⪅ࢆᑐ㇟࡜ࡋࡓᙜ◊✲࡛ࡣࠊྛ✀⾜ἲࡢ࠺ࡕࠊ⪷ḷࡀ᭱ࡶᴦࡋ࠸ࣉࣟࢢ࣒ࣛ࡜ࡋ࡚ዲ ࡲࢀ࡚࠸ࡓࠋᵝࠎ࡞య㦂ࢆ⤒࡚ࠊே⏕ࡢ⤊ᮎᮇ࡟࠶ࡓࡿேࠎ࡟࡜ࡗ࡚ࠊ⢭⚄ᛶࢆ῝ࡵࡿࣉ ࣟࢢ࣒ࣛࡣᚲせ࡛࠶ࢁ࠺ࡋࠊᐇ㝿࡟ዲࡲࢀ࡚࠸ࡓࠋࡋ࠿ࡋࠊᩥ໬ࡢ㐪࠸࡟ࡼࡗ࡚ࡣࠊࣉࣟ ࢢ࣒ࣛࢆᕤኵࡍࡿࡇ࡜ࡀồࡵࡽࢀࡼ࠺ $EVWUDFWRU ࡢ᥎ዡᗘ ᐙ᪘࡜ࡢ஺ὶࡀᑡ࡞ࡃே⏕ࡢ⤊ᮎᮇ࡟ྥ࠿࠺㧗㱋⪅࡟ᑐࡋࠊᢚ㨚ឤࢆ㍍ῶࡉࡏࡿࡶࡢ࡜ࡋ ࡚ࠊ㌟యⓗ࢚ࢡࢧࢧ࢖ࢬࡸࣜࣛࢡࢭ࣮ࢩࣙࣥࠊ࿧྾ἲࠊ⢭⚄ⓗ࣭ဴᏛⓗ࡞ほⅬࢆྵࡵࡓࣚ ࢞ࡢ⤫ྜⓗ࢔ࣉ࣮ࣟࢳࢆ᥎ዡࡍࡿ $EVWUDFWRUDQG'DWH 㔝ᆏぢᬛ௦ ᒸᏕ࿴ − 88 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)⤫ྜኻㄪ⑕㸧 ᩥ⊩ Ikai S, et al. Effects of yoga therapy on postural stability in patients with schizophrenia-spectrum disorders : A single-blind randomized controlled trial. Journal of Psychiatric Research, 2013,Vol. 47, pp1744-1750 Pubmed ID:23932244 ┠ⓗ ⤫ྜኻㄪ⑕࡛ࡣ㌟యⓗ୙Ᏻᐃࡀ㌿ಽࡢࣜࢫࢡࢆቑࡍࡓࡵ㔜せ࡞ၥ㢟࡛࠶ࡿࠋ⤫ྜኻㄪ⑕ᝈ ⪅ࡢጼໃᏳᐃ࡜ᰂ㌾ᛶ࡟ᑐࡍࡿࣚ࢞⒪ἲࡢຠᯝࢆ᳨ウࡍࡿࠋ ◊✲ࢹࢨ࢖ࣥ ▷┣᳨ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦VLQJOHEOLQG5&7㸧 ࢭࢵࢸ࢕ࣥࢢ ᒣ᲍┴ᒣ᲍┴❧໭⑓㝔⚄⤒⢭⚄⛉ 1 ᪋タ ཧຍ⪅ ⤫ྜኻㄪ⑕࠶ࡿ࠸ࡣ⢭⚄⑓ᛶ㞀ᐖ࡜デ᩿ࡉࢀࡓ ṓ௨ୖࡢእ᮶ᝈ⪅ ௓ධ ࣚ࢞⒪ἲ ᅇ ศ㐌 ᅇ඲ ᅇ㸦㸶㐌㸧 ࡑࡢᚋ ࠥ 㐌ࡣࢹ࢖ࢣ࢔࡟ཧຍ $UP௓ධ⩌ ⥅⥆୰ࡢ἞⒪㸩ࣚ࢞⩌ ྡ $UPࢥࣥࢺ࣮ࣟࣝ⩌ ⥅⥆἞⒪㸩ࢹ࢖ࢣ࢔ࣉࣟࢢ࣒ࣛ⩌ ྡ 667ᚰ⌮ᩍ⫱ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1. 㔜ᚰືᦂ᳨ᰝ㸦ࣟࣥ࣋ࣝࢢ⋡࡞࡝㸧 2.❧఩࡟ࡼࡿ๓ᒅࡢ ᐃ 3.㏣㊧ㄪᰝ࡟࠾࠸࡚ ձPositive and Negative Syndrome Scale 㸦PANSS, 㝧ᛶࠊ㝜ᛶ⑕≧㸧 ղ Drug-Induced Extrapyramidal Symptoms Scale 㸦㗹యእ㊰⑕≧㸧ճFACT-Sz 㸦⑕≧࡟ࡼࡿၥ㢟࡜♫఍ᶵ ⬟ホ౯㸧մ EroQol 5 dimensions㸦QoL㸧 յ CVR-R㸦ᚰ㟁ᅗ R-R 㛫㝸㸧 ௓ධᮇ㛫๓ᚋ㸦8 㐌ࠊࡉࡽ࡟ 16 㐌ࡢ㡯┠ࡶ࠶ࡾ㸧 ࠋ ୺࡞⤖ᯝ ௓ධᚋࠊࣚ࢞⩌ࡣࢥࣥࢺ࣮ࣟࣝ⩌࡟ẚ࡭࡚㔜ᚰືᦂィ࡛ࡢయᖿ㐠ື㊥㞳ࡢ㛗ࡉ(P=0.008) ࡜ࣟࣥ࣋ࣝࢢ⋡(P=0.009)ࠊ❧఩࡟ࡼࡿ๓ᒅ(P=0.014)ࡀᨵၿࡋࡓࠋ⮫ᗋⓗᣦᶆ࡛୧⩌㛫࡛ᕪ ࡀࡳࡽࢀࡓࡶࡢࡣ PANSS ࡢ㝜ᛶ⑕≧(P=0.014ࠊࣚ࢞⩌࡛ᚓⅬపୗ)࡜ FACT-Sz(P-=0.003ࠊ ࣚ࢞⩌࡛ቑຍ)ࡢࡳ࡛ࠊ௚ࡢ⤫ྜኻㄪ⑕ࡢ⮫ᗋ⑕≧࡟㛵㐃ࡍࡿᣦᶆ࡛ࡣ୧⩌࡛ᕪࡣ࡞࠿ࡗ ࡓࠋࣚ࢞⒪ἲ⩌࡟࠾࠸࡚ 8 㐌┠࡟♧ࡉࢀࡓຠᯝࡣࠊ16 㐌┠࡟࡯ࡰ࣮࣋ࢫࣛ࢖ࣥ࡟ᡠࡗࡓࠋ ⤖ㄽ ⤫ྜኻㄪ⑕ࢫ࣌ࢡࢺ࣒ࣛᝈ⪅ࡢጼໃᏳᐃ࡜ᰂ㌾ᛶ࡟㛵ࡍࡿࣚ࢞⒪ἲࡢຠᯝࡀึࡵ࡚ホ౯ ࡉࢀࡓࠋ8 㐌㛫ࡢࣚ࢞⒪ἲ࡛ጼໃືᦂࡣ᭷ព࡟ῶᑡࡋࡓࠋࣚ࢞ࡣ⤫ྜኻㄪ⑕ࢫ࣌ࢡࢺ࣒ࣛ ᝈ⪅ࡢጼໃᏳᐃࢆ㧗ࡵࠊ㌿ಽࡸ㦵ᢡࡢࣜࢫࢡῶᑡ࡟᭷ຠ࡛࠶ࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ௓ධ⩌ 8㸣 ⌮⏤ࡣ୧⩌ඹ࡟ྠពࡢ᧔ᅇࠊ௓ධ๓ࡢ⑕≧ࡢ෌⇞ࠊྜే⑕࡟ࡼࡿධ㝔 ࢥࣥࢺ࣮ࣟࣝ⩌ 㸣 ࣚ࢞ࡢヲ⣽ ࢛࣮࣒࢘࢔ࢵࣉ࡜ࡋ࡚➽⫗ࢆ࡯ࡄࡍ㐠ືࡢ࠶࡜ࠊ࢔࣮ࢧࢼ࡜ࡋ࡚ࠊࡡࡌࡾࡢ࣏࣮ࢬࠊ ❧఩࡟ࡼࡿ࣏࣮ࢬࠊኴ㝧♩ᣏࠊᒈࡢ࣏࣮ࢬࠊ࿧྾ἲࢆ⾜ࡗࡓࠋ 㸦࿧྾ἲࡢヲ⣽࡟ࡘ࠸࡚ ࡣ 6XSSOHPHQWDU\WDEOH ࢆཧ↷࡜グ㍕࠶ࡿࡢࡳ㸧 ࠋ▂᝿࡟ࡘ࠸࡚ࡣグ㍕࡞ࡋࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ⤫ྜኻㄪ⑕ᝈ⪅ࡢጼໃᏳᐃ࡜ᰂ㌾ᛶ࡟࠾ࡅࡿࠊࣚ࢞⒪ἲࡢຠᯝࡢ◊✲ࡣ㐣ཤ࡟࡞ࡃࠊ౯್ ࡀ࠶ࡿࠋࣚ࢞ࡢࢭࢵࢩࣙࣥࢆ⤫ྜኻㄪ⑕ᝈ⪅ྥࡅ࡟ᕤኵࡋࠊࢻࣟࢵࣉ࢔࢘ࢺ⋡ࢆῶᑡࡉࡏ ࡓⅬࡀ⯆࿡῝࠸ࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ᝈ⪅ࡢጼໃᏳᐃ࡜ᰂ㌾ᛶࢆ㧗ࡵࡿࡓࡵ࡟ࠊࣚ࢞ࢆ່ࡵࡿ $EVWUDFWRUDQG'DWH ᖹ⃝ᫀᏊ ᒸᏕ࿴ − 89 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)&⤫ྜኻㄪ⑕㸧 ᩥ⊩ Varambally S, et al. Therapeutic efficacy of add-on yogasana intervention in stabilized outpatient schizophrenia: Randomized controlled comparison with exercise and waitlist. Indian Journal of Psychiatry . 2012 ; 54(3): 227–232. Pubmed ID: 23226845 ┠ⓗ ⤫ྜኻㄪ⑕እ᮶ᝈ⪅࡟ᑐࡋ࡚ࣚ࢞࢔ࢧࢼ㏣ຍ௓ධࡢ἞⒪ⓗ᭷⏝ᛶࢆ᳨ウࡍࡿࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ WKH1DWLRQDO,QVWLWXWHRI0HQWDO+HDOWKDQG1HXURVFLHQFHV ᪋タ࢖ࣥࢻ ཧຍ⪅ ⤫ྜኻㄪ⑕࡜デ᩿ࡉࢀࡓእ᮶ᝈ⪅ ྡࠋᖹᆒᖺ㱋ࡣࣚ࢞⩌ ṓࠊ㐠ື⩌ ṓࠊᚅ ᶵ⩌ ṓࠋ⑓Ṕࡢᖹᆒ᭶ᩘࡣࠊࣚ࢞⩌ ࣧ᭶ࠊ㐠ື⩌ ࣧ᭶ࠊᚅᶵ⩌ ࣧ᭶ࠋ ௓ධ ࣏࣮ࢬ࡜࿧྾ἲࡢࡳࡢࣚ࢞ ᅇ ศ᭱ึࡢ ࠿᭶㛫 ᅇࠋ௓ධᚋࡶ⮬Ꮿ࡛ࡢᐇ⩦ࢆ ᥎ዡࠋ௓ධᚋࡢ ࠿᭶㛫ẖ᭶ࣇ࢛࣮ࣟ࢔ࢵࣉࢆ⾜ࡗࡓࠋ $UPࣚ࢞⩌ ྡࠋ㏻ᖖ἞⒪࡟ຍ࠼ࠊࣚ࢞ࢆ௓ධࠋ $UP㐠ື⩌ ྡࠋ㏻ᖖ἞⒪࡟ຍ࠼ࠊᶆ‽ⓗ࡞㐠ືࠋ $UPᚅᶵ⩌ ྡࠋ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1.PANSS ⤫ྜኻㄪ⑕ࡢ㝧ᛶ࣭㝜ᛶ⑕≧ホ౯ᑻᗘࠊ2.SOFS ♫఍ⓗ⫋ᴗⓗᶵ⬟ࢫࢣ࣮ࣝࠊ3. Extra Pyramidal Symptoms 㗹యእ㊰⑕≧ࠋ௓ධ๓࡜ 4 ࠿᭶ᚋࡢ 2 ᅇ ᐃࠋ ୺࡞⤖ᯝ ௓ධࡢ๓࡜ 4 ࠿᭶ᚋࡢ ᐃ࡛ࠊࣚ࢞⩌࡛ PANSS㸦㝜ᛶ㸦P<0.001㸧࡜⥲ྜ㸦P<0.001㸧㸧࡜ SOFS㸦P<0.001㸧ࡢⴭࡋ࠸ῶᑡࡀ㉳ࡇࡗࡓࠋ㐠ື⩌࡛ࡣ SOFS㸦P=0.004㸧࡛ῶᑡࡀ࠶ࡗࡓ ࡶࡢࡢࠊࡑࡢ௚ࡢ ᐃ࡛ࡣ㐠ື⩌ࡶᚅᶵ⩌ࡶⴭࡋ࠸ኚ໬ࡣ࡞࠿ࡗࡓࠋࣚ࢞⩌ࡣ㐠ື⩌㸦࢜ ࢵࢬẚ=5.000㸧 ࠊᚅᶵ⩌㸦࢜ࢵࢬẚ=5.167㸧ࡢ࡝ࡕࡽ࡜ẚ㍑ࡋ࡚ࡶ PANSS 㝜ᛶᚓⅬࡢᨵၿ ࢆᚓࡿྍ⬟ᛶࡣ 5 ಸࡢቑຍࢆࡶࡓࡽࡍࡇ࡜ࢆ♧ࡋࡓࠋPANSS ⥲ྜᚓⅬࡢほⅬ࠿ࡽࣚ࢞⩌ ࡟࠾ࡅࡿᨵၿࡢྍ⬟ᛶࡣᚅᶵ⩌㸦࢜ࢵࢬẚ= 6.576㸧ࡼࡾࡶ⣙ 6 ಸ࡛࠶ࡗࡓࠋ௓ධࡣࠊ⸆๣ ᛶ㗹యእ㊰⑕≧ࡢホ౯࡟ࡣᙳ㡪ࢆཬࡰࡉ࡞࠿ࡗࡓࠋ ⤖ㄽ ᩘᖺ㛫Ᏻᐃࡋࡓᢞ⸆἞⒪ࢆཷࡅ࡚࠸ࡿ⤫ྜኻㄪ⑕ᝈ⪅࡟ࠊࣚ࢞ࡢ 1 ࣨ᭶ࡢᐇ⩦࡜ࡑࡢᚋࡢ 3 ࣨ᭶ࡢ⮬Ꮿᐇ⩦ࢆ⾜࠺㏣ຍࡢ἞⒪ࡣࠊ㐠ືࢆ㏣ຍࡍࡿ἞⒪ࡸ㏻ᖖ἞⒪ࡼࡾࡶ㔜せ࡞ຠᯝ ࢆᥦ౪ࡋࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ゝཬ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࣚ࢞⩌ ྡࠊ㐠ື⩌ ྡࠊᚅᶵ⩌ ྡࠊィ ྡࡢ ࡀ᭱⤊ⓗ࡟ࢻࣟࢵࣉ࢔࢘ࢺࡋࡓࠋ ࣚ࢞ࡢヲ⣽ ≉ᐃࡢ࣏࣮ࢬ࡜࿧྾ἲ࡛ᵓᡂࡉࢀࡿࣚ࢞ࠋ▂᝿ࡣࠊ⢭⚄⑓ࢆᝏ໬ࡍࡿ༴㝤ᛶࡀ࠶ࡿࡓࡵࠊ ▂᝿ࡢᵓᡂせ⣲ࡣྵࡲ࡞࠸ࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ⤫ྜኻㄪ⑕࡟ᑐࡋ࡚㏻ᖖ἞⒪࡟ຍ࠼ࡓࣚ࢞ࡢຠᯝ࡟ࡘ࠸࡚᭷ព⩏࡞⤖ᯝࢆᚓࡽࢀࡓࠋཧຍ ⪅ࡢ⑓Ṕࡀᖹᆒ࡛ ᖺ࡯࡝࠶ࡾࠊᝈ⪅ᮏேࡸᝈ⪅ࡢ㏆ࡃ࡛ᬽࡽࡍேࠎࡢࡇ࡜ࢆ⪃࠼ࡿ࡜ ࡶࡗ࡜᪩ࡃࡇࡢ᭷ຠ࡞἞⒪ࢆ▱ࡾࡓ࠿ࡗࡓ࡛࠶ࢁ࠺ࠋ௒ᚋࡣࠊ⑓Ṕࡢ㛗ࡉ࡜ࣚ࢞ࡢຠᯝࡢ 㛵ಀ࡟ࡘ࠸࡚ࡢ◊✲ࡀࡉࢀࡿࡇ࡜ࢆᮇᚅࡋࡓ࠸ࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ࡢᝈ⪅࡟ᑐࡋ࡚ࠊ㏻ᖖ἞⒪࡟ຍ࠼ࣚ࢞ࢆᐇ⩦ࡍࡿࡇ࡜ࢆ່ࡵࡿࠋ $EVWUDFWRUDQG'DWH ᯇ⏣༓㔛 ᒸᏕ࿴ − 90 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)⤫ྜኻㄪ⑕㸧 ᩥ⊩ Visceglia E, et al: Yoga Therapy as an adjunctive Treatment for Schizophrenia: A Randomized, Controlled Pilot Study. The Journal of Alternative and Complementary Medicine (2011) 17(7), 601-607. PubMed ID:21711202 ┠ⓗ ⢭⚄⑓᪋タ࡟ධ㝔୰ࡢᡂே⤫ྜኻㄪ⑕ᝈ⪅ࡢ⑕≧࡜ 42/ ࡟ᑐࡍࡿࣚ࢞⒪ἲࣉࣟࢢ࣒ࣛࡢ ຠᯝࢆ᳨ウࡍࡿࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ ⡿ᅜࢽ࣮࣮ࣗࣚࢡࡢ⢭⚄⑓᪋タ㸦%URQ[3V\FKLDWULF&HQWHU%URQ[1<㸧 ཧຍ⪅ ྡ'60ϫࡢ➨ ㍈デ᩿࡛⤫ྜኻㄪ⑕࡜デ᩿ࡉࢀࡓ⮫ᗋⓗ࡟Ᏻᐃࡋࡓධ㝔ᝈ⪅ࠋᩘྡ ࡣ⤫ྜኻㄪᛶឤ᝟㞀ᐖࡲࡓࡣ 376' ࡜ేࡏ࡚デ᩿ࡉࢀ࡚࠸ࡿࠋࣚ࢞⩌ࡢ࠺ࡕ ྡࠊᚅᶵ⩌ ࡢ࠺ࡕ ྡࡣ➨ ㍈࡛ࡶ㞀ᐖ࠶ࡾ࡜デ᩿ࡉࢀ࡚࠸ࡿࠋ ௓ධ ࣚ࢞ࢭࣛࣆ࣮ ᅇ ศ㐌 ᅇ 㐌㛫 $UP௓ධ⩌ࣚ࢞⩌㸦 ྡ㸧 $UPࢥࣥࢺ࣮ࣟࣝ⩌ᚅᶵ⩌㸦 ྡ㸧௓ධヨ㦂ࢆ 㐌㛫⾜࡞ࡗࡓࠋ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ PANSS(඲⯡ⓗ࡞⤫ྜኻㄪ⑕ࡢ⢭⚄≧ែ)ࠊ WHOQOL-BREF (WHO QOL ㉁ၥ⣬) ࢆ௓ධ ๓ࠊ௓ධᚋ࡛ẚ㍑ࠋ ୺࡞⤖ᯝ ࣚ࢞⩌ࡣࢥࣥࢺ࣮ࣟࣝ⩌࡜ẚ㍑ࡋ࡚ࠊ PANSS ࡢ᭷ព࡞ᨵၿ[Total(㹮<.00), ୗ఩ᑻᗘ positive syndrome(p=.02), negative syndrome(p<.01), general psychopathology(p<.00), activation(p=.04), paranoia(p<.01), depression(p=.02)ࡀぢࡽࢀࡓࠋWHOQOL-BREF ࡣ Physical Health Domain 㸦p=.04)ࠊPsychological Domain(p<.01)ࡀ᭷ព࡟ᨵၿࡋ࡚࠸ࡓࠋ ⤖ㄽ ⢭⚄⑓᪋タ࡛἞⒪ࢆཷࡅ࡚࠸ࡿᡂே⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡋ࡚ࠊ㸶㐌㛫ࡢࣚ࢞⒪ἲࣉࣟࢢࣛ ࣒ࡣࠊࢥࣥࢺ࣮ࣟࣝ⩌ࡼࡾ⢭⚄⑓⌮࡜ QoL ࢆᨵၿࡋࡓࠋࡼࡾつᶍࡢ኱ࡁ࠸ࠊ࢔ࢡࢸ࢕ࣈ ࢥࣥࢺ࣮ࣟࣝࢆ⏝࠸ࡓ◊✲ࢆᐇ᪋ࡍࡿ࡭ࡁ࡛࠶ࡿࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ グ㍕࡞ࡋࠋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࢻࣟࢵࣉ࢔࢘ࢺ࡞ࡋࠋ ࣚ࢞ࡢヲ⣽ ࣚ࢞ࢭࣛࣆ࣮㸸㍍㈇ᢸࡢࣚ࢞ࢫࢺࣞࢵࢳࠊ࿧྾࡜㐃ືࡉࡏࡿ༢⣧࡞య᧯ࠊ༢⣧࡞࿧྾ἲྤ ࡃᜥࢆ㛗ࡃࡍࡿࡇ࡜ࢆᙉㄪࠊ࢔࣮ࢧࢼࠊ࡟ࡼࡾᵓᡂࠋ᭱ᚋ࡟ᣦᑟ⪅ࡢ࢞࢖ࢻ࡟ࡼࡿᘱ⦆ ἲࢆᐇ᪋ࠋయ᧯ࡢ✀㢮࡞࡝ࡣࢡࣛࢫ࣭ࢡࣛ࢖࢔ࣥࢺࡢ≧ἣ࡟ࡼࡾ⤌ࡳ᭰࠼࡚ᐇ᪋ࡍࡿ࡭ࡁ ࡜ࡢ⪃࠼᪉࠿ࡽࠊྛᅇ࡟ࡼࡾኚ᭦ࡋࡓࠋ▂᝿ࡣᐇ᪋ࡋ࡞࠿ࡗࡓࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ⤫ྜኻㄪ⑕࡟ᑐࡍࡿࣚ࢞⒪ἲࡢຠᯝࢆ᳨ウࡋࡓࣃ࢖ࣟࢵࢺࢫࢱࢹ࢕࡜ࡋ࡚ព⩏࠶ࡾࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡋ࡚᮲௳௜ࡁ່࡛ࡵࡿࠋ 㸦ᑐ㇟⪅ࡢᑡ࡞࠸ࣃ࢖ࣟࢵࢺࢫࢱࢹ࢕ࡢࡓࡵ㸧 $EVWUDFWRUDQG'DWH ᮧୖ┿ ᒸᏕ࿴ − 91 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)⤫ྜኻㄪ⑕㸧 ᩥ⊩ Behere RV, et al. Effect of yoga therapy on facial emotion recognition deficits, symptoms and functioning in patients with schizophrenia. Acta Psychiatr Scand 2011;123:147–53.Pubmed ID:20846271 ┠ⓗ ⤫ྜኻㄪ⑕࡛ࡣ㢦᝟ືㄆ▱㞀ᐖIDFLDOHPRWLRQUHFRJQLWLRQGHILFLW)(5'ࡀࡳࡽࢀࠊ ♫఍⫋ᴗⓗᶵ⬟ࢆᦆࡡࡿཎᅉ࡜࡞ࡗ࡚࠸ࡿࠋࡑࡇ࡛ᢠ⢭⚄⑓⸆࡛Ᏻᐃࡋ࡚࠸ࡿ⤫ྜኻㄪ⑕ ᝈ⪅ࡢ㢦᝟ືㄆ▱㞀ᐖ࡟ᑐࡍࡿࣚ࢞ࡢຠᯝࢆ᫂ࡽ࠿࡟ࡍࡿࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ ࢖ࣥࢻ࣭ࣂ࣮ࣥ࢞ࣟࣝᕷࡢ 1DWLRQDO,QVWLWXWHRI0HQWDO+HDOWKDQG1HXUR6FLHQFHV ཧຍ⪅ '60ϫ࡛⤫ྜኻㄪ⑕࡜デ᩿ࡉࢀࡓ ṓࡢᝈ⪅ ྡ ௓ධ 69<$6$ ࡢ⤫ྜኻㄪ⑕ᝈ⪅⏝ࣉࣟࢢ࣒ࣛ ศ㸯ࣨ᭶㛫ẖ᪥⥆ࡃ ࣨ᭶㛫ࡣ⮬Ꮿᐇ⩦ $UP௓ධ⩌ ࣚ࢞⩌ ྡ $UPࢥࣥࢺ࣮ࣟࣝ⩌ ࢚ࢡࢧࢧ࢖ࢬ⩌ ྡ ศ㸯ࣨ᭶㛫ẖ᪥ ࣨ᭶⮬Ꮿᐇ⩦ $UPࢥࣥࢺ࣮ࣟࣝ⩌ᚅᶵ⩌ ྡ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1. Positive and Negative Syndrome Scale 㸦PANSS,㝧ᛶࠊ㝜ᛶ⑕≧㸧2. Socio-Occupational Functioning Scale 㸦SOFC,♫఍⫋ᴗⓗᶵ⬟㸧3. Tool for Recognition of Emotions in Neuropsychiatric Disorders (TRENDS)ࠊTRENDS Accuracy Score (TRACSࠊ᝟ືⓗ⾲᝟ࢆṇ☜ ࡟ㄆ㆑)ࠋ௓ධ๓ࠊ2 ࣨ᭶ᚋࠊ4 ࣨ᭶ᚋࡢ 3 ᅇࠊ ᐃࠋ ୺࡞⤖ᯝ ௓ධ๓ࠊࣚ࢞ᐇ⩦⩌ࡣ௚ࡢ㸰⩌࡟ᑐࡋ࡚ࠊPANSS࣭Negative Symptoms Scale ࡀ᭷ព࡟㧗ࡃࠊ TRACS ࡀ᭷ព࡟ప࠿ࡗࡓࠋ௓ධࡢຠᯝ㸸ࣚ࢞⩌ࡢࡳ PANSS࣭Positive and Negative Symptom Scale (㸰ࣨ᭶ᚋࠊp=0.002, p<0.001), TRACS(㸰ࣨ᭶ᚋࠊp=0.003), SOFC(㸰ࣨ᭶ᚋࠊp<0.001) ࡀ᭷ព࡟ᨵၿࡋࡓࠋࡇࡢᨵၿຠᯝࡣ㸰࢝᭶ᚋ࡛᭱ࡶ኱ࡁ࠿ࡗࡓࡀࠊ4 ࣨ᭶ᚋࡢᨵၿࡶ᭷ព ࡛࠶ࡗࡓࠋ୍᪉ࠊ௚ࡢ㸰⩌࡛ࡣࠊࡇࢀࡽࡢᣦᶆ࡟ኚ໬ࡣ࡞࠿ࡗࡓࠋ ⤖ㄽ ࣚ࢞⒪ἲࡣᢠ⢭⚄⑓⸆࡟ࡼࡾ⑓≧ࡀᏳᐃࡋ࡚࠸ࡿ⤫ྜኻㄪ⑕ᝈ⪅ࡢ)(5'࡜♫఍⫋ᴗⓗᶵ ⬟ࢆᨵၿࡍࡿ௜ຍⓗ⒪ἲ࡜ࡋ࡚᭷⏝࡛࠶ࡿࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࣚ࢞⩌㸵ྡ ࢚ࢡࢧࢧ࢖ࢬ⩌ ྡ ᚅᶵ⩌ ྡ ࣚ࢞ࡢヲ⣽ ࣦ࢕ࣦ࢙࣮࢝ࢼࣥࢲ࣭࣮ࣚ࢞◊✲㈈ᅋ㸦69<$6$㸧ࡀ㛤Ⓨࡋࡓࣉࣟࢢ࣒ࣛࢆᣦᑟࠋ࣮ࣝࢬࢽ ࣥࢢ࢚ࢡࢧࢧ࢖ࢬࠊ࢔࣮ࢧࢼࠊ࿧྾ἲࠊࣜࣛࢡࢮ࣮ࢩࣙࣥ࠿ࡽᵓᡂࡉࢀ඲య࡛㸯᫬㛫ࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ඛ⾜◊✲ࡀஈࡋ࠸)(5'࡟ᑐࡍࡿࣚ࢞⒪ἲࡢຠᯝࢆ᳨ドࡋࡓࡇ࡜ࠊ≉࡟ࣨ᭶ᚋ᫬Ⅼ࡛ࡶຠ ᯝࡀ⥅⥆ࡋ࡚࠸ࡿⅬ࡛ព⩏ࡢ࠶ࡿᡂᯝ࡜⪃࠼ࡽࢀࡿࠋࡓࡔࠊᶆᮏศᕸࡢṇつᛶ࡟ࡘ࠸࡚ゝ ཬࡣ࡞࠸ࡀࠊᶆᮏᩘ࡟㚷ࡳࢀࡤࣃ࣓ࣛࢺࣜࢵࢡศᯒ࡟ࡼࡿ᳨ᐃ࡟ࡣ↓⌮ࡀ࠶ࡿ࡜ᛮࢃࢀ ࡿࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡋ࡚ᢞ⸆࡜୪⾜ࡋ࡚ࣚ࢞⒪ἲࢆᐇ⩦ࡍࡿࡇ࡜ࢆ᮲௳௜ࡁ່࡛ࡵࡿ $EVWUDFWRUDQG'DWH ᮧୖ┿ ᒸᏕ࿴ − 92 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)⤫ྜኻㄪ⑕㸧 ᩥ⊩ Vancampfort D, et al. State anxiety, psychological stress and positive well-being responses to yoga and aerobic exercise in people with schizophrenia: a pilot study: a randomized controlled trial. Disability and Rehabilitation.2011;33(8):684-689 Pubmed ID: 20718623 ┠ⓗ ⤫ྜኻㄪ⑕ᝈ⪅࡟ࠊࣚ࢞࠶ࡿ࠸ࡣ࢚࢔ࣟࣅࢡࢫࡢࢩࣥࢢࣝࢭࢵࢩࣙࣥ࡜ᑐ↷᮲௳࡛୙Ᏻࠊ ⢭⚄ⓗࢫࢺࣞࢫࠊ୺ほⓗᖾ⚟ឤࡢኚ໬࡟ࡘ࠸࡚ẚ㍑᳨ウࢆ⾜ࡗࡓࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ .RUWHQEHUJ ኱Ꮫᛴᛶᮇ⢭⚄⛉㸯᪋タ࣮ࣦ࢙ࣝࣥ࣋ࣝࢠ࣮ ཧຍ⪅ .RUWHQEHUJ ኱Ꮫᛴᛶᮇ⢭⚄⛉⑓Ჷ࡟ධ㝔ࡋ࡚࠸ࡿ⤫ྜኻㄪ⑕ࡶࡋࡃࡣ⤫ྜኻㄪᵝ㞀ᐖ࡜ デ᩿ࡉࢀࡓ⏨ᛶ ྡ㸦ᖹᆒᖺ㱋 s ṓ㸧 ࠊዪᛶ ྡ㸦s ṓ㸧ィ ྡࠋ ௓ධ ࣁࢱࣚ࢞ ᅇ ศ ྡࡢཧຍ⪅ࡣࣛࣥࢲ࣒࡞㡰␒࡛ࣚ࢞ࠊ࢚࢔ࣟࣅࢡࢫࠊ㐠ືࡣࡋ ࡞࠸ᑐ↷᮲௳ࡢ ࡘࡢࢭࢵࢩࣙࣥࢆ୍ᗘ⾜ࡗࡓࠋ $UPࣚ࢞ $UP࢚࢔ࣟࣅࢡࢫ ศ㛫⮬ศࡢዲࡁ࡞ᙉᗘ࡛࢚ࣝࢦ࣓࣮ࢱ࣮ࢆ₈ࡄࠋ $UPᑐ↷᮲௳ ศᏳ㟼ᗙ఩ࢆಖᣢ㸦୚࠼ࡽࢀࡓࡶࡢࢆㄞ᭩ࡍࡿࡇ࡜ࡣྍ⬟㸧 ࠋ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1.State Anxiety Inventory (SAI) ୙Ᏻ 2. Subjective Exercise Experiences Scale (SEES) ⢭⚄ⓗ ࢫࢺࣞࢫ࡜୺ほⓗᖾ⚟ឤࠋ௓ධ๓ᚋࡢ 2 ᅇ ᐃࠋ ୺࡞⤖ᯝ ୙Ᏻࡣࠊࣚ࢞ᚋ㸦P<0.0001㸧࡜࢚࢔ࣟࣅࢡࢫᚋ㸦P<0.0001㸧࡛㐠ື࡞ࡋᚋ࡜ẚ㍑ࡋ᭷ព࡟ ῶᑡࡋࡓࠋࣚ࢞ᚋ࡜࢚࢔ࣟࣅࢡࢫᚋ࡛ࡣ᭷ពᕪࡣぢࡽࢀ࡞࠿ࡗࡓࠋ ⢭⚄ⓗࢫࢺࣞࢫࡣࠊࣚ࢞ᚋ㸦P<0.0001㸧࡜࢚࢔ࣟࣅࢡࢫᚋ㸦P<0.0001㸧࡛௓ධᚋࡢ್ࡀ㐠 ື࡞ࡋᚋ࡜ẚ㍑ࡋ࡚᭷ព࡟పୗࡋࡓࠋࣚ࢞ᚋ࡜࢚࢔ࣟࣅࢡࢫᚋ࡛ࡣ᭷ពᕪࡣぢࡽࢀ࡞࠿ࡗ ࡓࠋ ୺ほⓗᖾ⚟ឤࡣࠊࣚ࢞ᚋ㸦P<0.0001㸧࡜࢚࢔ࣟࣅࢡࢫᚋ㸦P<0.0001㸧࡛௓ධᚋࡢ್ࡀ㐠ື ࡞ࡋᚋ࡜ẚ㍑ࡋ࡚᭷ព࡟ୖ᪼ࡋࡓࠋࣚ࢞ᚋ࡜࢚࢔ࣟࣅࢡࢫᚋ࡛ࡣ᭷ពᕪࡣぢࡽࢀ࡞࠿ࡗ ࡓࠋ ⤖ㄽ ࣚ࢞࡜᭷㓟⣲㐠ືࡣ≧ែ୙Ᏻ࡜ࢫࢺࣞࢫࢆῶᑡࡉࡏࠊ୺ほⓗᖾ⚟ឤࢆቑຍࡉࡏࡿ⤖ᯝ࡜࡞ ࡗࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ グ㍕࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࢻࣟࢵࣉ࢔࢘ࢺ࡞ࡋࠋ ࣚ࢞ࡢヲ⣽ ᪂ᚠ⎔⣔ࡢ࢛࣮࣑࢘ࣥࢢ࢔ࢵࣉ ศ⭡ᘧ࿧྾カ⦎ ศ࢔࣮ࢧࢼ ศ㸦D ᒣࡢ࣏࣮ࢬ Eᮌࡢ࣏࣮ࢬ F⊧ࡢ࣏࣮ࢬ Gࢥࣈࣛࡢ࣏࣮ࢬ H⭸࡜⬚ࡢ࣏࣮ࢬ㸧 ࣜࣛࢡࢮ࣮ࢩࣙࣥ㸦6KDYDVDQD ྵࡴ㸧 ศ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ⤫ྜኻㄪ⑕ᝈ⪅ࡀ♫఍⏕άࢆ㏦ࡿ୰࡛ឤࡌࡿ୙Ᏻࡸ⢭⚄ⓗࢫࢺࣞࢫࢆᑐฎࡍࡿ᪉ἲࢆ㌟ ࡟ࡘࡅࡿࡇ࡜ࡀࠊࡑࡢ᪉ࡢ 42/ ࢆ㧗ࡵࡿ㝿࡟࡜࡚ࡶ㔜せ࡞ࡇ࡜࡜࡞ࡗ࡚ࡃࡿࠋࡑࡢᑐฎ᪉ ἲࡢ୍ᡭẁ࡜ࡋ࡚ࣚ࢞ࢆ఩⨨࡙ࡅࡿࡇ࡜ࡀฟ᮶ࡿࡇ࡜ࡣ࡜࡚ࡶ⯆࿡῝ࡃࠊᡭ㍍࡟ཧຍ࡛ࡁ ࡿࣚ࢞ࡢሙࢆቑࡸࡍࡇ࡜ࡸࠊ᝟ሗࢆᥦ౪ࡍࡿࡇ࡜ࡀฟ᮶ࢀࡤ࡜ឤࡌࡓࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕⪅ࡢ୙Ᏻ࣭ࢫࢺࣞࢫ㍍ῶࠊ୺ほⓗᖾ⚟ឤྥୖ࡟㛵ࡋ࡚ࠊࣚ࢞ࢆ່ࡵࡿࠋ $EVWUDFWRUDQG'DWH ୍⏫ᑠⓒྜ ᒸᏕ࿴ − 93 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ 㸦)&⤫ྜኻㄪ⑕㸧 ᩥ⊩ Jayaram N, et al. Effect of yoga therapy on plasma oxytocin and facial emotion recognition deficits in patients of schizophrenia. Indian Journal of Psychiatry. 2010 ; 112, 597-601. Pubmed ID:24049210 ┠ⓗ ᢠ⢭⚄⑓⸆ࢆ᭹⏝୰ࡢ⤫ྜኻㄪ⑕ᝈ⪅࡟࠾࠸࡚ࠊࣚ࢞⒪ἲࡢ⑕≧ࠊ♫఍⫋ᴗⓗ࡞ᶵ⬟ࠊ㢦⾲᝟ㄆ▱㞀ᐖࠊ⾑₢࢜࢟ࢩࢺࢩࣥࣞ࣋ࣝ࡟ཬࡰࡍຠᯝࢆ᳨ウࡍࡿࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ 1DWLRQDO,QVWLWXWHRI0HQWDO+HDOWKDQG1HXUR6FLHQFHV ᪋タࣂ࣮ࣥ࢞ࣟࣝ࢖ࣥࢻ ཧຍ⪅ ⤫ྜኻㄪ⑕࡜デ᩿ࡉࢀࠊᑡ࡞ࡃ࡜ࡶ 㐌㛫ࡢᢠ⢭⚄⑓⸆ࢆᏳᐃࡋ࡚ᢞ୚ࡉࢀ࡚࠸ࡿ ṓ 㹼 ṓࡢ ྡࠋ ௓ධ ⤫ྜኻㄪ⑕ࡢࡓࡵࡢࣚ࢞ ࣨ᭶ࠋ୧⩌ࡢᝈ⪅ࡣᢠ⢭⚄⑓⸆࡟ࡼࡗ࡚Ᏻᐃࡋࡓᝈ⪅ࠋ $UPࣚ࢞⩌ ྡ $UPᚅᶵ⩌ ྡ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ 1.SAPS ⤫ྜኻㄪ⑕ࡢ㝧ᛶ⑕≧ホ౯ᑻᗘࠊ2.SANS ⤫ྜኻㄪ⑕ࡢ㝜ᛶ⑕≧ホ౯ᑻᗘࠊ3.SOFS ♫఍ⓗ⫋ᴗⓗᶵ⬟ࢫࢣ࣮ࣝࠊ4.TRENDS ⢭⚄⚄⤒⑌ᝈ࡟࠾ࡅࡿឤ᝟ㄆ㆑㸦4-1.TRENDS accuracy score ⢭ᗘࢫࢥ࢔㸦TRACS㸧 ࠊ4-2.TRENDS over identification score ㆑ูࢫࢥ࢔ (TOI)㸧 ࠋ௓ධ๓ᚋࡢ 2 ᅇ ᐃࠋ ୺࡞⤖ᯝ ௓ධᮇ㛫ᚋࠊ୧⩌࡜ࡶ࡟ SAPSࠊSANS ᚓⅬࡣ᭷ព࡟ᨵၿࡋࡓࡀࠊࣚ࢞⩌ࡢࡳ SOFS ♫఍ ⓗ⫋ᴗⓗᶵ⬟ࢫࢣ࣮ࣝ㸦P<0.001㸧 ࠊTRACS ឤ᝟ㄆ㆑⢭ᗘ㸦P<0.001㸧 ࠊTOI ឤ᝟ㄆ㆑㆑ู 㸦P=0.03㸧ࡀᨵၿࡋࠊ⾑₢࢜࢟ࢩࢺࢩࣥࣞ࣋ࣝ㸦P=0.01㸧ࡀቑຍࡋࡓࠋ ⤖ㄽ ࡇࡢ◊✲ࡣࠊᢠ⢭⚄⑓⸆ࢆ᭹⏝ࡍࡿ⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡋ࡚㏣ຍࡋ࡚⾜ࢃࢀࡿࣚ࢞⒪ἲࡀ ⑕≧ࠊ♫఍⫋ᴗⓗ࡞ᶵ⬟࡜㢦⾲᝟ㄆ▱ࢆᨵၿࡍࡿࡢ࡟᭷┈࡞ᙺ๭ࡀ࠶ࡿࡇ࡜ࢆ♧ࡋࡓࠋ㔜せ࡞Ⅼࡣࣚ࢞⩌࡛⾑₢࢜࢟ࢩࢺࢩࣥࣞ࣋ࣝࡀቑຍࡋࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ ゝཬ࡞ࡋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ࣚ࢞⩌ࡢࢻࣟࢵࣉ࢔࢘ࢺࡣ࡞࠿ࡗࡓࡀࠊᚅᶵ⩌࡛ ேࡀࢻࣟࢵࣉ࢔࢘ࢺࡋࡓࠋ ࣚ࢞ࡢヲ⣽ ࢖ࣥࢻ࣭ࣂ࣮ࣥ࢞ࣟࣝࡢࣚ࢞ࡢ኱Ꮫ 69<$6$ ࡟ࡼࡗ࡚㛤Ⓨࡉࢀࡓ⤫ྜኻㄪ⑕ࡢࡓࡵࡢ≉ᐃ ࡢࣚ࢞⒪ἲࣉࣟࢢ࣒ࣛࠋᘱ⦆ࡍࡿࡓࡵࡢືࡁࠊ࿧྾ἲࠊ6XU\DQDPDVNDUD ኴ㝧♩ᣏࠊᗙ఩࣭ ௮ྥࡁ࣭࠺ࡘఅࡏ࡛ࡢ࣏࣮ࢬࢆ࿧྾ἲࡸࣜࣛࢡࢮ࣮ࢩࣙࣥࢸࢡࢽࢵࢡࢆ⏝࠸࡚⾜࠺ࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ⤫ྜኻㄪ⑕ᝈ⪅ࡢ⑕≧࡞࡝࡟ࣚ࢞⒪ἲࡀ᭷ព࡛࠶ࡿࡇ࡜ࡀࢃ࠿ࡗࡓࡢ࡛࠶ࡿࡀࠊࡇࢀࡣ࢖ ࣥࢻ࡛ࡶ⌋ࡋ࠸ࣚ࢞ࡢ኱Ꮫ࡛࠶ࡿ 69<$6$ ࡢ㛤Ⓨࣉࣟࢢ࣒࡛ࣛ࠶ࡿࡇ࡜ࡶᛀࢀ࡚ࡣ࡞ࡽ ࡎࠊ≉࡟⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡍࡿࣚ࢞ࡢෆᐜࡸᣦᑟࡢ௙᪉࡟ὀពࡀᚲせ࡛࠶ࡿࡇ࡜ࡀ❚ࢃ ࢀࡿࠋ⾑₢࢜࢟ࢩࢺࢩࣥ࡟㛵ࡋ࡚ࡣࠊ⤫ྜኻㄪ⑕ᝈ⪅ࡔࡅ࡛࡞ࡃྠࡌࣚ࢞ࣉࣟࢢ࣒ࣛࢆ⑕ ≧ࡢ࡞࠸೺ᗣ࡞ே࡟௓ධࡋࡓሙྜࡢ◊✲࡟ࡘ࠸࡚ࡶᐇ᪋ࡉࢀࡿࡇ࡜ࢆᮇᚅࡍࡿࠋ 㸦࢜࢟ࢩࢺࢩࣥࡣ⤫ྜኻㄪ⑕⑕≧ࢆᨵၿࡍࡿ࡜ゝ࠺ሗ࿌ࡶ࠶ࡿ㸧 $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ࡢ⸆≀⒪ἲࢆ⾜ࡗ࡚࠸ࡿᝈ⪅࡟㏣ຍࡋ࡚ࣚ࢞ࢆ௓ධࡍࡿࡇ࡜ࢆ່ࡵࡿࠋ⌮⏤ࡣ ⑕≧ࠊ♫఍ⓗᶵ⬟ࠊ⾲᝟ㄆ▱ࡢᨵၿࡔࡅ࡛࡞ࡃࠊ࢜࢟ࢩࢺࢩࣥࡢࣞ࣋ࣝࡶቑຍࡍࡿࡇ࡜ࡀ ࢃ࠿ࡗࡓࡓࡵࠋ $EVWUDFWRUDQG'DWH ᯇ⏣༓㔛 ᒸᏕ࿴ − 94 − 㸳⢭⚄࠾ࡼࡧ⾜ືࡢ㞀ᐖ )⤫ྜኻㄪ⑕ ᩥ⊩ Duraiswamy G, et al. Yoga therapy as an add-on treatment in the management of patients with schizophrenia –a randomized controlled trial. Acta Psychia Scand 2007sep;116(3): 226-32. Pubmed ID:17655565 ┠ⓗ ⤫ྜኻㄪ⑕࡛᭹⸆἞⒪୰ࡢᝈ⪅࡟ᑐࡍࡿࣚ࢞ࡢ௓ධࡀ࡝ࡢࡼ࠺࡞ຠᯝࢆࡶࡓࡽࡍ࠿ࠋ ◊✲ࢹࢨ࢖ࣥ ࣛࣥࢲ࣒໬ẚ㍑ヨ㦂㸦5&7㸧 ࢭࢵࢸ࢕ࣥࢢ National Institute of Mental Health and Neuro Sciences, Bangalore, India ཧຍ⪅ ⤫ྜኻㄪ⑕ࡢ ྡ ௓ධ 6ZDPL9LYHNDQDQGD<RJD$QXVDQGKDQD6DPVWKDQD69<$6$࡟ࡼࡿࠕ⤫ྜࣚ࢞⒪ἲࠖ ▂᝿ࡣྵࡲ࡞࠸ࠋ ᫬㛫㐌 ᅇ 㐌㛫ࠋࡑࡢᚋ⮬Ꮿᐇ⩦ࢆ ᫬㛫㐌 ᅇ ࢝᭶㛫 $UP௓ධ⩌ᢠ⢭⚄⸆㸩ࣚ࢞⩌ Q $UPࢥࣥࢺ࣮ࣟࣝ⩌ᢠ⢭⚄⸆㸩࢚ࢡࢧࢧ࢖ࢬ⩌Q ࣚ࢞࡜ྠ㢖ᗘࡢ௓ධ ୺࡞࢔࢘ࢺ࣒࢝ホ౯ᣦᩘ ୺せホ౯㡯┠㸸ձPANSS(⤫ྜኻㄪ⑕ࡢ㝧ᛶ⑕≧ࠊ㝜ᛶ⑕≧ࠊᢚ࠺ࡘࠊAnergia score)ࠊղSocial and Occupational Functioning Scale (SOFSࠊ♫఍⫋ᴗⓗᶵ⬟) ๪ḟホ౯㡯┠㸸WHOQOL-BREF (QOL, ㌟యⓗࠊ ⢭⚄ⓗࠊ ♫఍ⓗࠊ ⎔ቃⓗ)ࠊ ๪స⏝㸸Abnormal Involuntary Movement Scale (AIMS) ࡜ Simpson Angus Scale for Extrapyramidal Symptoms(SOFS)ࢆ௓ධ๓ࠊ4 ࣨ᭶ࡢ 2 ᅇ ᐃࠋ ୺࡞⤖ᯝ ձ௓ධᮇ㛫ᚋࠊPANSS ⥲ᚓⅬ࡜ࢧࣈࢫࢣ࣮ࣝᚓⅬ࡜ SOFS ⥲ᚓⅬࡣࠊ୧⩌࡛పୗࡋࡓࠋ ୧⩌㛫ࡢẚ㍑࡛ࡣࠊPANSS 㝧ᛶ⑕≧ࢆ㝖ࡁࠊࣚ࢞⩌ࡢ᪉ࡀ᭷ព࡟ᨵၿࡋࡓࠋ ղQoL ࡢࢫࢥ࢔ࡣࠊࣚ࢞⩌࡛ࡢࡳ᭷ព࡟ᨵၿࡋࡓࠋࣚ࢞⩌ࡣࠊࢥࣥࢺ࣮ࣟࣝ⩌ࡼࡾ᭷ព ࡟㧗࠸ࢫࢥ࢔ࢆ♧ࡋࡓࠋ ճ๪స⏝ࡣ୧᪉ࡢᣦᶆ࡛ࠊ୧⩌㛫࡛ᕪࡣࡳࡽࢀ࡞࠿ࡗࡓࠋ ⤖ㄽ ࣚ࢞ࡶ㌟యⓗ㐠ືࡶ⤫ྜኻㄪ⑕ࡢ⑕≧࡟ᑐࡋ࡚ྠ➼ࡢຠᯝࢆ♧ࡋࡓࡀࠊࣚ࢞⩌ࡢ᪉ࡀࡼࡾ ຠᯝⓗ࡛࠶ࡗࡓࠋᢠ⢭⚄⑓⸆࡛἞⒪୰ࡢ⤫ྜኻㄪ⑕ᝈ⪅ࡀ࢔ࢻ࢜ࣥ⒪ἲ࡜ࡋ࡚ࣚ࢞ࢆ⾜࡞ ࠺࡜⢭⚄⑓⌮ⓗഃ㠃ࡸከࡃࡢ⤖ᯝ࡛᭷ຠᛶࡀ♧၀ࡉࢀࡓࠋ Ᏻ඲ᛶ࡟㛵ࡍࡿゝཬ 㔜⠜࡞᭷ᐖ஦㇟㸦ᗁぬࠊΰ஘ࠊ⮬ẅ࡞࡝㸧ࡣ࡞࠿ࡗࡓࠋ ࢻࣟࢵࣉ࢔࢘ࢺ⋡࡜ࢻࣟࢵࣉ࢔࢘ࢺ⩌ࡢ≉ᚩ ௓ධ⩌Q ࢥࣥࢺ࣮ࣟࣝ⩌Q ࣚ࢞ࡢヲ⣽ ࣚ࢞ࢭࣛࣆ࣮㸸D6LWKLOLNDUDQD9\D\DPDࠊEVXU\DQDPDVNDUࢆྵࡴ࢔࣮ࢧࢼࠊF࿧ ྾ἲࠊGࣜࣛࢡࢮ࣮ࢩࣙࣥࢸࢡࢽࢵࢡ࡛ᵓᡂࡉࢀࠊࡑࢀࡒࢀࡢ᫬㛫㓄ศࡣDEF 㸯㸸㸯㸸㸯࡛࠶ࡗࡓࠋ▂᝿ࡣᐇ᪋ࡏࡎࠋ $EVWUDFWRU ࡢࢥ࣓ࣥࢺ ࣚ࢞ࡢ௓ධࡣ἞⒪୰ࡢ⤫ྜኻㄪ⑕ᝈ⪅ࡢ⑕≧ࡸ♫఍⫋ᴗⓗᶵ⬟ࢆᨵၿࡋࠊ42/ ࢆᨵၿࡍࡿ ࡇ࡜ࡀ♧၀ࡉࢀࡿࠋ௒ᚋࡣࣚ࢞ࡀ⚄⤒⣔࡟ලయⓗ࡟࡝ࡢࡼ࠺࡞ᶵᗎ࡛స⏝ࡍࡿࡢ࠿◊✲ࡀ ᮇᚅࡉࢀࡿࠋ $EVWUDFWRU ࡢ᥎ዡᗘ ⤫ྜኻㄪ⑕ᝈ⪅࡟ᑐࡋ࡚ࣚ࢞㸦▂᝿ࢆྵࡲ࡞࠸㸧ࢆ່ࡵࡿࠋ $EVWUDFWRUDQG'DWH ᒸభ࿴ Ώ㎶࠶ࡸ ᒸᏕ࿴ − 95 −