ࣉࣟࢢ࣒࣭ࣛᢒ㘓 ᖺ ᭶ ᪥ 㒔ᕷࢭࣥࢱ࣮࣍ࢸࣝ 㛗 ᒾ⏣ᖾ୍ http://www.japan-neuromodulation.org/ ➨㸰㸷ᅇ ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ 㛗 ᒾ⏣ ᖾ୍ ᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ ᩍᤵ ᪥ 2015 ᖺ 4 ᭶ 25 ᪥ ᅵ᭙᪥ 9 30 ศ㹼16 35 ศ ሙ 㒔ᕷࢭࣥࢱ࣮࣍ࢸࣝ 5 㝵 ㆟ᐊ࢜ࣜ࢜ࣥ ᮾி㒔༓௦⏣༊ᖹἙ⏫ 2-4-1 TEL: 03ï3265ï8221㸦௦⾲㸧 㻌 㻌 㻌 㐠Ⴀົᒁ ᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ ࠛ101-8310 ᮾி㒔༓௦⏣༊⚄⏣㥴Ἑྎ 1-8-13 TEL: 03-3219-8122 FAX: 03-3219-8341 E-mail㸸[email protected] ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ Ṕ௦㛗 ྡဨ ୪ᮌ ⩏ ➨ ᅇࡲ࡛ࡣ㟁Ẽ่⃭⒪ἲ◊✲ ➨ ᅇ ᖺ ර㢌 ṇ⩏ ➨ ᅇ ᖺ 㕥ᮌ ኴ ⌮ ➨ ᅇ ᖺ ୗᆅ ᜏẎ 㛵 㞞Ꮚ ᒾ⏣ ᖾ୍ ᵳ Ὀ ➨ ᅇ ᖺ 㧗 බ᭸ ᑠᕝ ⠇㑻 ∦ᒣ ᐜ୍ ຍ⸨ ኳ⨾ ➨ ᅇ ᖺ ᆤᕝ Ꮥᚿ 㰻⸨ ὒ୍ ㇂ཱྀ┿ ᡞ⏣ ୍㞝 ➨ ᅇ ᖺ బ⸨ ኵ ⰼᒸ ୍㞝 ༙⏣ ᗣᘏ ᖹᯘ ⚽⿱ ➨ ᅇ ᖺ ▼ᓥ Ṋ୍ ᐑᓮ ᮾὒ ᮧᕝ 㔜 ᒣᮏ 㝯 ➨ ᅇ ᖺ 㧗ᶫ 㛗㞝 ➨ ᅇ ᖺ ᮏ ሕྐ ▼Ἑ ᘏ㈆ ➨ ᅇ ᖺ ホ㆟ဨ ୖ ᓫ 㩗⃝ ⪽ ᭷⏣ ⱥᏊ ෆᒣ ༟ஓ Ᏹ㔝 Ṋྖ ᓥ ⚽つ ᑠ➟ཎ ಇ୍ ᑠ 㝯ⱥ Ლ⏣ Ὀ୍ டᒣ ⱱᶞ ᕝྜ ㅬ ᕝ┿⏣ ᶞே ㈗ᓥ ᬕᙪ ྂ℩ ὒ୍ ᚋ⸨ ᜨ ἑ ❶ඵ ➨ ᅇ ᖺ ᅵ⫧ ಙஅ ➨ ᅇ ᖺ Ụ ༓ᘅ ➨ ᅇ ᖺ ᑠᕝ ⚽㐨 ➨ ᅇ ᖺ 㕥ᮌ ኴ ➨ ᅇ ᖺ ᑠᯘ ୍ኴ ᑠᯇᓮ 㝯 ⠛Ọ ṇ㐨 ▮㔝 ⱥ㞝 ➨ ᅇ ᖺ ᮡᒣ ᠇Ⴙ 㛵 ๎ ᖹ Ꮥ⮧ ∦ᒣ ᐜ୍ ➨ ᅇ ᖺ ୰㔝 ┤ᶞ すᕝ Ὀṇ ᰿ᮏ ᫂ᐅ ➨ ᅇ ᖺ ✄᳃ ⪔ᖹ ᶫᮏ 㝯⏨ 㤿ሙ ᗣᙪ ᖹᡞ ᨻྐ ∦ᒣ ᐜ୍ ➨ ᅇ ᖺ ῝㇂ ぶ ⸨ ṇ⨾ ⣽ぢ ୍ ⰼᒸ ୍㞝 ➨ ᅇ ᖺ ቑ⏣ ㇏ ᯇ⏣ ┾୍㑻 ୕ᾆ 㑥ஂ ୪ᮌ ⩏ ➨ ᅇ ᖺ ୕ᅜ ಙၨ ᐑᇛ 㟹 ᮧᒸ ⠊⿱ ➨ ᅇ ᖺ ᮧᕝ 㔜 ᮧୖ 㞞 ᳃⏣ ຌ ᳃ᒣ ⴙ⚽ ᐑᓮ ᮾὒ ➨ ᅇ ᖺ ᒣᇛ ⨾ ᶓᒣ ᚭኵ ྜྷ㔝 ⠜⥴ ➨ ᅇ ᖺ ᒣᮏ 㝯 㸦ᩗ⛠␎ ༑㡢㡰㸧 ➨ ᅇ ᖺ ༙⏣ ᗣᘏ ᑠᕝ ⠇㑻 ➨ ᅇ ᖺ ົᒁ ຍ⸨ ➨ ᅇ ᖺ ᪥ᮏᏛ་Ꮫ㒊⬻⚄⤒እ⛉Ꮫ⣔⚄⤒እ⛉Ꮫศ㔝 ࠛᮾி㒔ᯈᶫ༊㇂ཱྀୖ⏫ ᵳ ➨ ᅇ ᖺ 7(/㸦ෆ⥺ 㸧 ➨ ᅇ ᖺ ᒾ⏣ )$; 㰻⸨ ➨ ᅇḟᮇ ᖺ㰻 E-mail: [email protected] 㸦ᢸᙜ㸸ᑠᯘ୍ኴ㸧 http://www.japan-neuromodulation.org/ ኳ⨾ Ὀ ᖾ୍ ὒ୍ ሙࡢ㏻ ᆅୗ㕲᭷ᴦ⏫⥺ࠕ㯜⏫㥐༙ࠖⶶ㛛᪉㠃㸯␒ฟཱྀࡼࡾᚐṌ㸲ศ ᆅୗ㕲᭷ᴦ⏫⥺࣭༙ⶶ㛛⥺ࠕỌ⏣⏫㥐ࠖ㸲␒࣭ ␒ฟཱྀࡼࡾᚐṌ㸲ศ ᆅୗ㕲༡⥺ࠕỌ⏣⏫㥐ࠖ㸷␒ฟཱྀࡼࡾᚐṌ㸱ศ ᆅୗ㕲ࡢෆ⥺࣭㖟ᗙ⥺ࠕ㉥ᆏぢ㝃㥐ࠖ㹂ฟཱྀࡼࡾᚐṌ㸶ศ 㹈㹐୰ኸ⥺ࠕᅄ㇂㥐ࠖ㯜⏫ฟཱྀࡼࡾᚐṌ㸯㸲ศ 㒔ࣂࢫᖹἙ⏫㸰┠ࠕ㒔ᕷࢭࣥࢱ࣮๓ࠖୗ㌴㸦᪂ᶫ㥐㹼ᕷࣨ㇂㥐㹼ஂಖ㥐㸧 㤳㒔㧗㏿ 㟘ࡀ㛵ฟཱྀࡼࡾ㸳ศ 㸨㥔㌴ሙࡣ㝈ࡾࡀ࠶ࡾࡲࡍࡢ࡛ࠊබඹࡢ㏻ᶵ㛵ࢆࡈ⏝ࡢ࠺࠼ࡈ᮶ሙࡃࡔࡉ࠸ࠋ 1 ሙෆ 㸳㹄 ཧຍ㈝ z ဨ z 㠀ဨ ᙜ᪥Ꮫཷ࡚࠾ᨭᡶ࠸ࡃࡔࡉ࠸ࠋ 2 ≉ูㅮ₇࣭ࢩ࣏ࣥࢪ࣒࢘ ࠝ≉ูㅮ₇ࠞ 13:20 㹼 14:20 ࠝᗙ㛗㸸ᒾ⏣ᖾ୍ ඛ⏕ࠞ ③ࡳࡳࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ ᰠᮌ㝯 ඛ⏕ ⮬↛⛉Ꮫ◊✲ᶵᵓ ⏕⌮Ꮫ◊✲ᡤ ࠝࢩ࣏ࣥࢪ࣒࣭࢘៏ᛶ⑊③ࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥࠞ 14:30 㹼 16:30 ࠝᗙ㛗㸸 ᡞ⏣୍㞝 ඛ⏕㰻⸨ὒ୍ ඛ⏕ࠞ ៏ᛶ⑊③⣽⬊グ᠈ ᡂ⏣ᖺ ඛ⏕ 㸦ᫍ⸆⛉Ꮫ㸧 ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ⚄⤒่⃭⒪ἲ ⣽ぢ୍ ඛ⏕ 㸦㜰ᏛᏛ㝔 ་Ꮫ⣔◊✲⛉㸧 ៏ᛶ⑊③ᑐࡍࡿ⬨㧊่⃭⒪ἲ ୖᓥ㈼ဢ ඛ⏕ 㸦177 ᮾ᪥ᮏ㛵ᮾ㝔㸧 3 ࢱ࣒ࢸ࣮ࣈࣝ 9:30 9:35 10:35 10:55 11:35 12:05 13:20 14:20 14:30 16:30 16:35 17:00 19:00 㛤ᣵᣜ㸦㛗 ᒾ⏣ᖾ୍㸧 ୍⯡₇㢟 ⑊③㸦㸴㢟㸧 ᗙ㛗㸸㛵㞞Ꮚ ඛ⏕㸦㡰ኳᇽᏛ་Ꮫ㒊㝃ᒓ㡰ኳᇽ་㝔㸧 ఇ᠁ ୍⯡₇㢟 㐠ື㸦㸲㢟㸧 ᗙ㛗㸸㇂ཱྀ┿ ඛ⏕㸦ᮾி㒔❧⚄⤒㝔㸧 ୍⯡₇㢟 ࡑࡢ㸦㸱㢟㸧 ᗙ㛗㸸ᖹᯘ⚽⿱ ඛ⏕㸦ᅜ❧ዉⰋ་⒪ࢭࣥࢱ࣮㸧 ୍⯡㣗ሙ㸸࢜ࣜ࢜ࣥ⌮࣭ホ㆟ဨ㸦㣗㸧㸸ࢫࣂࣝ ≉ูㅮ₇③ࡳࡳࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ ᰠᮌ㝯 ඛ⏕⮬↛⛉Ꮫ◊✲ᶵᵓ ⏕⌮Ꮫ◊✲ᡤ ᗙ㛗㸸ᒾ⏣ᖾ୍ ඛ⏕㸦᪥ᮏᏛ㸧 ఇ᠁ ࢩ࣏ࣥࢪ࣒࢘㸸៏ᛶ⑊③ࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ㸦㸱㢟㸧 ᗙ㛗㸸ᡞ⏣୍㞝 ඛ⏕㸦㛗ᓮᏛ㸧 㰻⸨ὒ୍ ඛ⏕㸦㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉㸧 㛤ᣵᣜ㸦㛗 ᒾ⏣ᖾ୍㸧 ➨ ᅇ ③ࡳࡢ⚄⤒⛉Ꮫ◊✲㸦࢜ࣜ࢜ࣥ㸧 ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ࣭③ࡳࡢ⚄⤒⛉Ꮫ◊✲ ྜྠ᠓ぶ 4 ₇⪅ࡢࡈෆ z ୍⯡₇㢟ࡣⓎ⾲㛫 ศࠊ㉁ᛂ⟅㸱ศ࡞ࡗ࡚࠸ࡲࡍࠋⓎ⾲㛫ࢆཝ Ᏺࡋ࡚ࡃࡔࡉ࠸ࠋ z ࢫࢡ࣮ࣜࣥࡣ୍㠃࡛ࡍࠋ z 3& ࡢࡳ⏝ྍ⬟࡛ࡍࠋࣅࢹ࢜ࠊࢫࣛࢻࡣ⏝࡛ࡁࡲࡏࢇࠋ z ࣉࣟࢢ࣒ࣛ㛤ጞ㸯㛫๓ࡲ࡛ཷࢆ࠾㢪࠸ࡋࡲࡍࠋ z ࡈ⮬ศ࡛ 3& ࢆࡈᣢཧࡃࡔࡉ࠸ࠋ㟁※ࢣ࣮ࣈࣝࡶࡈᣢཧࡃࡔࡉ࠸ࠋ z 3& ࡢࢫ࣮ࣜࣉタᐃࡣࠕ2))ࠖࡋ࡚࠾࠸࡚ࡃࡔࡉ࠸ࠋ z ࣂࢵࢡࢵࣉࡋ࡚ࠊ&'5 86% ࣓࣮ࣔࣜࢆࡈᣢཧࡃࡔࡉ࠸ࠋ z ᥋⥆ࢣ࣮ࣈࣝࡣࠕ࢜ࢫࠖࡢ 0LQL'68% ࣆࣥ㸦 ิ ࣆࣥࡎࡘ㸧ࢆ ⏝ពࡋࡲࡍࠋࡇࢀ௨እࡢ➃Ꮚࢆ᭷ࡍࡿ 3& ࡢሙྜࡣࠊኚࢣ࣮ࣈࣝࢆࡈ ᣢཧࡃࡔࡉ࠸ࠋ 5 ➨㸰㸷ᅇ ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ ࣉࣟࢢ࣒ࣛ 㛤ᣵᣜ9:30 㹼 9:35 㛗㸸ᒾ⏣ᖾ୍㸦᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ㸧 ୍⯡₇㢟㸯㸸⑊③9:35 㹼 10:35 ᗙ㛗㸸㛵㞞Ꮚ㸦㡰ኳᇽᏛ་Ꮫ㒊㝃ᒓ㡰ኳᇽ་㝔 㯞㓉࣭࣌ࣥࢡࣜࢽࢵࢡᩍᐊ㸧 1-1 ୗ⫥ࡢ㞴ᛶ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ + ࢥࣝᘧ ࡢᏐࢥࣝᘧ⤒㢌☢Ẽ่⃭ࡢຠᯝẚ㍑ ΎỈኈ ᅭᑿ▱அ ⣽ぢ୍ ᚋ⸨㞝Ꮚ ᶓỤ ᙳᒣᝆ ᰡ⃝⌶ྐ ᢲ㔝ᝅ ᖹ⏣㞞அ ㈗ᓥᬕᙪ ྜྷᓠಇᶞ 㰻⸨ὒ୍ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒እ⛉Ꮫ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒ᶵ⬟⏕Ꮫ ᡭ๓㝔⬻⚄⤒እ⛉ ⟪㠃ᕷ❧㝔⚄⤒ෆ⛉ ᇸ⋢┴❧ᑠඣ་⒪ࢭࣥࢱ࣮ 1-2 ⬻༞୰ᚋ⑊③ᑐࡍࡿ 6&6 ⒪ຠᯝࡢண పᐜ㔞ࢣࢱ࣑ࣥⅬ⒪ἲࢆ⏝࠸ࡓ᳨ウ Prediction of the efficacy of SCS in patients with post-stroke pain すᕝὈṇ ⏿ගᙪ 㕥ᮌ ᑠᕝᙲ ᑠ➟ཎ㑥 ᒾᡭ་⛉Ꮫ⬻⚄⤒እ⛉ ᒾᡭ་⛉Ꮫ㯞㓉⛉ 1-3 ୰ᯡᛶ⬻༞୰ᚋ⑊③ᑐࡍࡿ⬨㧊่⃭⒪ἲࡢຠᯝ The effect of spinal cord stimulation for central post stroke pain ୖᓫ ⏣♸ బࠎ⏣ ᪂ග㜿௨Ꮚ బࠎᮌ㐩ஓ ᒸ㷂୕ಖᏊ ட⏣㞞༤ Ᏻཎ㝯㞝 ఀ㐩 ᒸᒣᏛᏛ㝔 ⬻⚄⤒እ⛉ 1-4 ⭜㒊⬨ᰕ⟶⊃✽ᑐࡍࡿ⬨㧊่⃭⒪ἲ Spinal cord stimulation for the lumbar spinal canal stenosis ❧ᒣ┿࿃ ụెዉᏊ ⏣୰ಙᙪ Ᏹ㔝Ṋྖ ₶グᛕ㝔 㯞㓉⛉࣌ࣥࢡࣜࢽࢵࢡ 6 1-5 ୕ཫ⚄⤒③ᑐࡍࡿ & ᮎᲈ⚄⤒㔝㙀㏻㟁่⃭ࡢヨࡳ C2 peripheral nerve field stimulation using electroacupuncture for the patients with trigeminal neuralgia. Report of 3 cases. ▱ஂࡍࡳࢀ 㩗⃝⪽ Ḉᗞ㝧 ⟃Ἴᢏ⾡Ꮫಖ⛉Ꮫ㒊㝃ᒓᮾす་Ꮫ⤫ྜ་⒪ࢭࣥࢱ࣮ ⟃Ἴᢏ⾡Ꮫಖ⛉Ꮫ㒊ಖᏛ⛉㙀⅍Ꮫᑓᨷ 1-6 ៏ᛶ㢌③࣭㢁㒊③ᑐࡍࡿࣁ࣮ࣥ࢞ᑕࡢ᪂ࡓ࡞ᛂ⏝ࡢ᳨ウ Clinical application of hanger reflex to patients with chronic headache and neck pain ᪫ 㞝ኈ బ⸨ ᮍ▱ ⏣୰ ᑑ▱ ୰ᮧ ᣅே ᝆẼ Ლᮏ ⿱அ 㔠ἑ⬻⚄⤒እ⛉㝔 ⬻⚄⤒እ⛉ 㟁Ẽ㏻ಙᏛ ⥲ྜሗᏛ ῭⏕ᯇᒣ㝔 10:35 㹼 10:55 Coffee Break ୍⯡₇㢟㸰㸸㐠ື10:55 㹼 11:35 ᗙ㛗㸸㇂ཱྀ┿㸦ᮾி㒔❧⚄⤒㝔 ⬻⚄⤒እ⛉㸧 2-1 㢁㒊ࢪࢫࢺࢽᑐࡍࡿ⤒㢌☢Ẽ่⃭ἲࡢຠᯝ The effect of 1Hz-repetitive transcranial magnetic stimulation on 10 patients with cervical dystonia ᮧᒸ ⠊⿱ 㔜᳃ ⛱ ᳃ᒸᇶᾈ ᰗᕝࣜࣁࣅࣜࢸ࣮ࢩࣙࣥ㝔 ⬻⚄⤒እ⛉ ஂ␃⡿Ꮫ་Ꮫ㒊 ⬻⚄⤒እ⛉ ῭⏕ᯇᒣ㝔 2-2 ⬻༞୰ᚋᡓᑐࡍࡿ⬻⓶㉁㐠ື㔝่⃭ࡢຠᯝ㸸⬻῝㒊่⃭⒪ἲࡢẚ㍑ࡽ MCS for post-stroke tremor: Comparison with DBS therapy ᒣᮏ㝯 Ώ㎶ ゅග୍㑻 ῲᩄᶞ ຍ⣡ ᑠᯘ୍ኴ ᓥ⚽つ ῝㇂ぶ ྜྷ㔝⠜⥴ ∦ᒣᐜ୍ ᪥ᮏᏛ⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝⚄⤒እ⛉Ꮫศ㔝 2-3 ࣃ࣮࢟ࣥࢯࣥᑐࡍࡿ 671'%6㸸㛗ᮇⓗ᭷ຠ࡞ࡢࡣ࠸࡞ࡿ㸽 STN-DBS for PD treatment: What are the expected long-term beneficial effects on patients? ῝㇂ぶ Ώ㎶ ຍ⣡ ᑠᯘ୍ኴ ᓥ⚽つ ྜྷ㔝⠜⥴ ᒣᮏ㝯 ᪥ᮏᏛ⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝⚄⤒እ⛉Ꮫศ㔝 7 2-4 ៏ᛶ⬻༞୰ᚋࡢ㐠ື㞀ᐖᑐࡍࡿ⬨㧊่⃭⒪ἲ Spinal cord stimulation may enhances motor recovery in chronic stroke す㔝ඞᐶ ᒣཱྀ༟ ᕷ❧ゅ㤋⥲ྜ㝔⬻⚄⤒እ⛉ ୍⯡₇㢟㸱㸸ࡑࡢ11:35 㹼 12:05 ᗙ㛗㸸ᖹᯘ⚽⿱㸦ᅜ❧ዉⰋ་⒪ࢭࣥࢱ࣮ ⬻⚄⤒እ⛉㸧 S-1 どᗋୗ᰾่⃭⾡ᚋࡢㄆ▱ᶵ⬟ࡢపୗ ୰㔝┤ᶞ ᐑෆṇᬕ ຍ⸨ኳ⨾ ㏆␥Ꮫ་Ꮫ㒊⬻⚄⤒እ⛉ S-2 ⚄⤒่⃭ࢩࢫࢸ࣒ᇙタ⾡࠾ࡅࡿ 6XUJLFDO6LWH,QIHFWLRQ66,ࡢ᳨ウ Surgical Site Infection of the neuro stimulator devices Ώ㎶ ゅග୍㑻 ῲᩄᶞ ᅄᲄඞ ຍ⣡ ᑠᯘ୍ኴ ᓥ⚽つ ῝㇂ぶ ྜྷ㔝⠜⥴ ᒣᮏ㝯 ∦ᒣᐜ୍ ᪥ᮏᏛ་Ꮫ㒊⬻⚄⤒እ⛉Ꮫ⣔⚄⤒እ⛉Ꮫศ㔝 ᪥ᮏᏛ་Ꮫ㒊⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒እ⛉Ꮫศ㔝 S-3 ぬ㓰ࢧࣝ⭡ഃ㐠ື๓㔝ࢽ࣮ࣗࣟࣥࡢ⇕่⃭ᑐࡍࡿᛂ⟅ Neuronal response to thermal stimuli in monkey ventral premotor cortex ᾏ㔝ಇᖹ ᒾ⏣ᖾ୍ ᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ 㣗 ୍⯡㣗ሙ㸸࢜ࣜ࢜ࣥ ⌮࣭ホ㆟ဨ㸦㣗㸧 㸸ࢫࣂࣝ 8 12:05 㹼 13:20 12:20 㹼 13:10 ≉ูㅮ₇13:20 㹼 14:20 ᗙ㛗㸸ᒾ⏣ᖾ୍㸦᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ㸧 ③ࡳࡳࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ Neuromodulation of pain and itch perception ᰠᮌ㝯ࡁࡂ࣭ࡾࡹ࠺ࡍࡅ ⮬↛⛉Ꮫ◊✲ᶵᵓ ⏕⌮Ꮫ◊✲ᡤ ⤫ྜ⏕⌮◊✲⣔ ᩍᤵ 14:20 㹼 14:30 Coffee Break ࢩ࣏ࣥࢪ࣒࢘㸸៏ᛶ⑊③ࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ 14:30 㹼 16:30 ᗙ㛗㸸ᡞ⏣୍㞝㸦㛗ᓮᏛ㸧 㰻⸨ὒ୍㸦㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉㸧 S-1 ៏ᛶ⑊③⣽⬊グ᠈ Chronic pain and cell memory ᡂ⏣ᖺ ᫍ⸆⛉Ꮫ ⸆⌮Ꮫᩍᐊ ඛ➃⏕⛉Ꮫ◊✲ࢭࣥࢱ࣮/6WD5 S-2 ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ⚄⤒่⃭⒪ἲ Neurostimulation therapies for neuropathic pain ⣽ぢ୍ ΎỈኈ ᚋ⸨㞝Ꮚ ᰡ⃝⌶ྐ ᢲ㔝ᝅ ㈗ᓥᬕᙪ ྜྷᓠಇᶞ 㰻⸨ὒ୍ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒ᶵ⬟⏕Ꮫ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒እ⛉Ꮫ S-3 ៏ᛶ⑊③ᑐࡍࡿ⬨㧊่⃭⒪ἲ Spinal cord stimulation for patients with chronic pain ୖᓥ ㈼ဢ NTT ᮾ᪥ᮏ㛵ᮾ㝔࣌ࣥࢡࣜࢽࢵࢡ⛉ 㛢ᣵᣜ16:30 㹼 16:35 㛗㸸ᒾ⏣ᖾ୍㸦᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ㸧 㸺ᘬࡁ⥆࠸࡚ࠊ③ࡳࡢ⚄⤒⛉Ꮫ◊✲ࢆ⾜࠸ࡲࡍ㸼 ➨ ᅇ ③ࡳࡢ⚄⤒⛉Ꮫ◊✲㸦ሙ㸸㸳㝵࢜ࣜ࢜ࣥ㸧17:00 㹼 19:00 ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛཧຍド࡛ࠊཧຍࡍࡿࡇࡀ࡛ࡁࡲࡍࠋ ⤊ᚋࠊ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ࣭③ࡳࡢ⚄⤒⛉Ꮫ◊✲ྜྠ᠓ぶࢆணᐃࡋ࡚࠾ࡾࡲࡍࠋ 9 ➨㸶ᅇ ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛ ᣦᐃㅮ⩦ ᪥㸸ᖹᡂ㸰㸵ᖺ㸲᭶㸰㸳᪥㸦ᅵ㸧 㹼 ሙ㸸㒔ᕷࢭࣥࢱ࣮࣍ࢸࣝ ᣦᐃㅮ⩦ሙ㸸㸳) ࢫࣂࣝ ༗ ๓ 10:00 ~ 12:00 ࡢ 㒊 ⬨㧊่⃭ࡢᇶ♏ ᪥ᮏᏛ⬻⚄⤒እ⛉ ᑠᯘ୍ኴ ඛ⏕ ⬨㧊่⃭ࡢᛂ⏝ ᒸᒣᏛ⬻⚄⤒እ⛉ ୖᓫ ඛ⏕ 㣗㸦㸳) ࢜ࣜ࢜ࣥ㸧 12:05 ~ 13:20 ༗ ᚋ 13:30 ~ 15:30 ࡢ 㒊 ⬻῝㒊่⃭ࡢᇶ♏ ᒾᡭ་⛉Ꮫ⬻⚄⤒እ⛉ すᕝὈṇ ඛ⏕ ⬻῝㒊่⃭ࡢᛂ⏝ ᪥ᮏᏛᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫ ῝㇂ぶ ඛ⏕ ఇ᠁ 15:30 ~ 15:45 15:45 ~ 16:15 ᣦᐃㅮ⩦ಟࢸࢫࢺ ࠝ་⒪ሗᥦ౪⪅ࡢࡳࠞ 㸦)ࢫࣂࣝ㸧 10 ≉ูㅮ₇ ③ࡳࡳࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥ ࡁࡂ ࡾࡹ࠺ࡍࡅ ᰠᮌ 㝯 ⮬↛⛉Ꮫ◊✲ᶵᵓ ⏕⌮Ꮫ◊✲ᡤ ⤫ྜ⏕⌮◊✲⣔ᩍᤵ Neuromodulation of pain and itch perception Ryusuke Kakigi, M.D., Ph.D. Professor, Department of Integrative Physiology, National Institute for Physiological Sciences ࣄࢺ࡛ࡢ③ࡳࡳࡢ⬻ෆㄆ▱ᶵᵓࢆࠊ㧗࠸㛫ศゎ⬟㸦࣑ࣜ⛊༢㸧ࢆ᭷ࡍࡿ⬻Ἴࠊ ⬻☢ᅗࠊ㧗࠸✵㛫ศゎ⬟ࢆ᭷ࡍࡿᶵ⬟ⓗ☢Ẽඹ㬆⏬ീI05,ࢆ⏝࠸࡚ゎᯒࡋ࡚࠸ࡿࠋ ㏆ᖺࡢ③ぬ◊✲ࡢࢺࣆࢵࢡࢫࡢ㸯ࡘࡣࠊ㐠ືࡢ㝖③ຠᯝ࡛࠶ࡿࠋࡋࡋࠊࡑࡢ⬻ෆ࣓࢝ ࢽࢬ࣒ࡣ᫂ࡽࡉࢀ࡚࠸࡞࠸ࠋ࡞ࡐ㐠ືࡣ㝖③ຠᯝࡀ࠶ࡿࡢࠊࡑࢀ㛵ಀࡍࡿ⬻ 㒊ࡣࡇࠊࡘ࠸࡚᭱᪂ࡢ◊✲ᡂᯝࢆᚚ⤂ࡋࡓ࠸ࠋ㐠ືྠᵝࠊ③ぬㄆ▱ࡣࠊ ࠕὀពࠖ࡞ࡢືࡼࡗ࡚ࡶࡁࡃᙳ㡪ࡉࢀࡿࠋ࠼ࡤࠊ⚾㐩ࡣࠊᐇ㝿③ࡳ่⃭ࢆ ࠼ࡽࢀ࡞ࡃ࡚ࡶ③࠸ឤࡌࡿࡀ࠶ࡿࠋࡑࢀࡣࠕᚰࡢ③ࡳࠖ⛠ࡉࢀࡿሙྜࡀከ࠸ࠋ ື㛵㐃῝࠸⬻㎶⦕⣔ࠊ≉ᖏ≧ᅇᓥᅇࡀ㛵ಀ῝࠸ࡇࡀ᫂ࡽ࡞ࡾࡘࡘ࠶ࡿࠋ ⚄⤒࣓࣮ࢪࣥࢢᡭἲࢆ㥑ࡍࡿࡇࡼࡾࠊື㛵ಀ῝࠸៏ᛶ⑊③ࡢ⬻ෆ࣓࢝ࢽࢬ ࣒ࢆ᫂ࡽࡋࠊ⸆ຠᯝࡢ⛬ᗘࡶᩘ್ࡉࢀࡿྍ⬟ᛶࡀ㧗࠸ࠋ ୡ⏺࡛ึࡵ࡚ࠊ㏻㟁่⃭ࡼࡿࡳⓎ⏕⨨ࢆ㛤Ⓨࡋࠊࡳࡢ⬻ෆㄆ▱ᶵᵓࡢゎ᫂ࢆ ⾜ࡗ࡚࠸ࡿࠋᕥྑ⬻༙⌫ࡢᗈ⠊࡞㒊άືࡀぢࡽࢀࠊ③ࡳㄆ▱㢮ఝࡋ࡚࠸ࡿࡀࠊ ᴂ๓㒊㸦SUHFXQHXV㸧ࡣࡳ่⃭ࡔࡅ≉␗ⓗάືࡀぢࡽࢀࡓࠋ ࠕேࡢࡳࡣఏᰁ ࡍࡿࠖࡀࠊࡑࡢࡣࠊᓥᅇ⬻ᇶᗏ᰾ࡢ┦㛵ࡀቑࡍࡇࡀ᫂ࡽ࡞ࡗࡓࠋ ࠕᥙ ࡃᛌឤࢆぬ࠼ࡿࠖࡣࠕሗ㓘⣔ࠖ⛠ࡉࢀࡿ⬻ᇶᗏ᰾ࡢ⥺᮲య୰⬻ࡀάືࡍࡿ ࢆ᫂ࡽࡋࡓࠋࡉࡽࠊ⤒㢌┤ὶ㟁Ẽ่⃭ἲW'&6ࢆ⏝࠸ࡓࡳࡢᢚไຠᯝࡘ ࠸࡚ࡶ⤂ࡋࡓ࠸ࠋ 11 S-1 ៏ᛶ⑊③⣽⬊グ᠈ ᡂ⏣ ᖺ ᫍ⸆⛉Ꮫ ⸆⌮Ꮫᩍᐊ ඛ➃⏕⛉Ꮫ◊✲ࢭࣥࢱ࣮/6WD5 Chronic pain and cell memory Minoru Narita Dept. Pharmacol., Hoshi Univ. Sch. Pharm. Pharmaceut. Sci. Life Science Tokyo Advanced research center (L-StaR) ࠕ③ࡳࠖࡣ⏕యᑐࡍࡿ༴ᐖࢆឤཷࡋ࡚ࠊ⏕యࢆ㜵ᚚࡍࡿࡓࡵᚲせ࡞ឤぬᛂ࡛࠶ ࡿࠋࡋࡋ࡞ࡀࡽࠊእയࠊࢫࢺࣞࢫ࡞ࡽࡧ⏕ά⩦័࡞࡛⏕ࡌࡿ㞴ᛶ㸭៏ᛶ⑊③ ࡛ࡣࠊṇᖖ࡞ᮎᲈ-⬨㧊-⬻㛫ࡢᶵ⬟ࢿࢵࢺ࣮࣡ࢡ࡛࠶ࡿ“③ࡳఏ㐩⤒㊰”ࡢྛᡤ࡛ᜏᖖᛶ ࡢ◚⥢ࡀ⏕ࡌ࡚࠸ࡿࡓࡵࠊಟ㸭⒪ࡀᅔ㞴࡞ࡿࠋࡇ࠺ࡋࡓ③ࡳࡢ៏ᛶࡣࠊ⬨㧊 㸭⬻࠾ࡅࡿᚋ⏕ⓗࠊᬌⓎⓗ㑇ఏᏊⓎ⌧ಟ㣭㸦࢚ࣆࢪ࢙ࢿࢸࢡࢫಟ㣭㸧ࡼࡿ⣽⬊グ ᠈ࡀᐤࡍࡿྍ⬟ᛶࡀ⪃࠼ࡽࢀࡿࠋ ࡑࡇ࡛ᮏࢩ࣏ࣥࢪ࣒࡛࢘ࡣࠊ៏ᛶ⑊③ࣔࢹࣝື≀ࢆ⏝࠸ࠊ㛫࠾ࡼࡧ✵㛫⥙⨶ⓗ࡞࢚ ࣆࢪ࢙ࢿࢸࢡࢫゎᯒࡘ࠸࡚ゝཬࡍࡿࠋࡲࡓࠊ⚄⤒ᶵ⬟ኚ╔┠ࡋࠊ⑊③ୗ࠾ࡅ ࡿ⬻⚄⤒ᶵ⬟ኚࡸ mRNA/miRNA Ⓨ⌧ኚືࢆకࡗࡓ⬻ෆሗ㓘⣔㸭ື⣔ࢿࢵࢺ࣮࣡ ࢡ␗ᖖᛂ⟅ࡢ⥙⨶ⓗゎᯒࢆᥦࡍࡿࠋࡉࡽࠊ࣑࢜ࢡࢫゎᯒࡣࡶࡼࡾࠊ࢜ࣉࢺࢪ࢙ࢿ ࢸࢡࢫᡭἲࠊࢣ࣑࢝ࣝࢪ࢙ࢿࢸࢡࢫᡭἲࠊ⣽⬊ศ㞳ἲࠊචᛂ⟅ゎᯒ࡞ࡼࡾᚓ ࡽࢀࡓ⤖ᯝࢆ⤫ྜࡋࡓ③ࡳ࠾ࡅࡿ࣐ࢡ࢚ࣟࣥࢻࣇ࢙ࣀࢱࣉࢆ♧ࡋࠊ㞴ᛶ⑊③ࡢ ⒪ἲࡘ࠸࡚㆟ㄽࡋࡓ࠸ࠋ 12 S-2 ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ⚄⤒่⃭⒪ἲ ⣽ぢ୍ ΎỈኈ ᚋ⸨㞝Ꮚ ᰡ⃝⌶ྐ ᢲ㔝ᝅ ㈗ᓥᬕᙪ ྜྷᓠಇᶞ 㰻⸨ὒ୍ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒ᶵ⬟⏕Ꮫ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒እ⛉Ꮫ Neurostimulation therapies for neuropathic pain Koichi Hosomi1,2, Takeshi Shimizu1,2, Yuko Goto1,2, Takufumi Yanagisawa2, Satoru Oshino2, Haruhiko Kishima2, Toshiki Yoshimine2, Youichi Saitoh1,2 1Department of Neuromodulation and Neurosurgery, Osaka University Graduate School of Medicine 2Department of Neurosurgery, Osaka University Graduate School of Medicine ⚄⤒㞀ᐖᛶ⑊③13ࡢ⒪ࡣࠊࡣࡌࡵ⸆≀⒪ࡀ⾜ࢃࢀࡿࡀࠊ⸆≀⒪ࡢࡳ࡛ࡣࢥࣥ ࢺ࣮ࣟࣝࡀ༑ศ࡛࠶ࡿࡇࡀᑡ࡞ࡃ࡞࠸ࠋࡑࡢࡼ࠺࡞ᑐࡋ࡚ࠊ⚄⤒่⃭⒪ἲ࡞ ࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥࡀ⾜ࢃࢀ࡚࠸ࡿࠋくⓗ࡞⚄⤒่⃭⒪ἲࡋ࡚ࡣࠊ⬻῝ 㒊่⃭⒪ἲ'%6ࠊ୍ḟ㐠ື㔝㟁Ẽ่⃭⒪ἲ(0&6ࠊ⬨㧊่⃭⒪ἲ6&6ࠊᮎᲈ⚄⤒่⃭ ⒪ἲ316ࠊ㠀くἲࡋ࡚ࠊ⤒㢌☢Ẽ่⃭U706ࠊ⤒㢌┤ὶ่⃭W'&6࡞ ࡀ࠶ࡿࠋᡃࠎࡣࡲ࡛ (0&6 ࢆ ࠊ୍ḟ㐠ື㔝ᑐࡍࡿ U706 ࢆ ௨ୖࡢ 13 ࢆᑐ㇟⾜ࡋ࡚ࡁࡓࠋ(0&6 ࡢ㛗ᮇⓗ࡞᭷ຠ⋡ࡣ ࡛࠶ࡗࡓࠋU706 ࡣࠊ୍ḟ㐠ື㔝 ᑐࡍࡿ㧗㢖ᗘ่⃭+] ௨ୖࡀ᭷ຠ࡛࠶ࡾࠊከタඹྠࢡࣟࢫ࣮࢜ࣂ࣮ẚ㍑ヨ㦂࡛ࡶࠊ 㐌㛫㐃᪥่⃭ࡢᏳᛶ᭷ຠᛶࡀ☜ㄆࡉࢀ࡚࠸ࡿࠋU706 ࡢ㝖③ຠᯝࡣ୍ⓗ࡛࠶ࡾࠊ 㸯ᅇࡢ่⃭ࡢࡳ࡛ࡣ༑ศ࡛࠶ࡿࡓࡵࠊ⧞ࡾ㏉ࡋ⾜ࡍࡿᚲせࡀ࠶ࡿࠋࡑࡢࡓࡵࠊᐇ⮫ ᗋࡢᛂ⏝ࡣࠊࡼࡾຠᯝࡢᮇᚅ࡛ࡁࡿ่⃭ࢩࢫࢸ࣒ࡸ่⃭᪉ἲࠊࡼࡾ⡆౽⾜ࡀྍ ⬟࡞่⃭⨨ࡀᚲせ࡞ࡿࠋ⌧ᅾࠊ᪂ࡓ࡞⮫ᗋ◊✲่࡛⃭᮲௳ࡢ᳨ウࠊ㝖③ᶵᗎࡢゎ᫂ ࢆ⾜࠺ࡶࠊ⏘Ꮫ㐃ᦠࢆ㏻ࡌ࡚ඹྠ㛤Ⓨࡋࡓ㐃᪥่⃭ᑐᛂࡋࡓ่⃭⨨ࡢ㦂ࢆ ‽ഛ୰࡛࠶ࡿࠋ୰ᯡ⚄⤒⣔ࡢࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥࢆ୰ᚰࠊ⮬㦂ࢆྵࡵ࡚⤂ ࡍࡿࠋ 13 S-3 ៏ᛶ⑊③ᑐࡍࡿ⬨㧊่⃭⒪ἲ ୖᓥ㈼ဢ 177 ᮾ᪥ᮏ㛵ᮾ㝔࣌ࣥࢡࣜࢽࢵࢡ⛉ Spinal cord stimulation for patients with chronic pain Kenya Kamijima Department of Pain Clinic. KANTO MEDICAL CENTER NTT EC, Tokyo, Japan ៏ᛶ⑊③ᑐࡋ࡚ᡃࠎ࣌ࣥࢡࣜࢽࢵࢡ⛉࡛ࡣࠊࡑࡢ③ࡳࡢཎᅉࡀࡇ࠶ࡿࢆホ౯ ࡋ࡞ࡀࡽ⒪ࢆ⾜ࡗ࡚࠸ࡿࠋ⸆≀⒪ἲ௨እ⚄⤒ࣈࣟࢵࢡ⒪ἲࢆ⾜࠺ࡀࠊࡇࢀࡣ⒪ࡔ ࡅ࡛ࡣ࡞ࡃデ᩿ⓗព⩏ࡶྵࡲࢀࡿࠋࡇ࠺࠸ࡗࡓ⒪ࡢࡳ࡛ࡣ③ࡳࡢࢥࣥࢺ࣮࡛ࣟࣝࡁ࡞ ࠸ሙྜࠊ6SLQDOFRUGVWLPXODWLRQ௨ୗ 6&6ࡢ㐺ᛂࢆ᳨ウࡋ࡚࠸ࡃࡀࠊࡑࡢ㝿ࡶ⚄⤒ ࣈࣟࢵࢡ⒪ἲࡢ⤖ᯝࢆཧ⪃ࡍࡿࠋ6&6 ࡣࡢ⒪࡛ࡣⰋ࠸⤖ᯝࡀᚓࡽࢀ࡞࠸៏ᛶ㞴 ᛶ⑊③ࢆ㍍ῶࡉࡏࡿࡇࡀ࠶ࡿୖᶵ⬟ⓗ࡞ᨵၿࢆࡶࡓࡽࡍࡶ࠶ࡿࠋࡓࡔࡋࠊ6&6 ࡣ ࡢࡶ᭷ຠࡣゝ࠼࡞࠸ࡓࡵࠊࢺࣛࣝࢆ⾜࠸ࡑࡢ᭷ຠᛶࢆࡳ࡚ᮏ᳜㎸ࡳࢆ⾜ ࠺ࡼ࠺ࡋ࡚࠸ࡿࠋ่⃭ࡀ③ࡳࡢ࠶ࡿ㒊ឤࡌ࡞࠸ሙྜࠊࡲࡓࠊ่⃭ࢆឤࡌ࡚ࡶ③ࡳ ࢆ㍍ῶࡉࡏࡿࡇࡀ࡛ࡁ࡞࠸ሙྜ࡞ࡣᮏ᳜㎸ࡳࢆ⾜ࢃ࡞࠸ࠋࡋࡋࠊ᭷ຠస⏝ࡋ ࡚ࡶᮏ᳜㎸ࡳ⮳ࡽ࡞࠸ࡇࡀ࠶ࡿࠋ␗≀ࡀయෆ࠶ࡿࡇࡢᢠឤࠊࡑࡢᚋࡢ⏕ά ࡢไ㝈࡞ࡀཎᅉ࡞ࡿ⪃࠼ࡽࢀࡿࠋᮏ㑥࡛ࡣ ♫ࡢ 6&6 ࡀ⏝ྍ⬟࡛ࡑࢀࡒࢀ ≉ᚩࡀ࠶ࡿࡀࠊྛ♫ࡶࡉࡽ᪂ࡓ࡞่⃭ἲࡸࢹࣂࢫ࡞ࢆ㛤Ⓨࡋ࡚࠾ࡾḢ⡿࡛ࡣࡍ ࡛⏝ࡉࢀ࡚࠸ࡿࡶࡢࡶ࠶ࡿࠋᚋࡑࢀࡽࢆ⏝ࡍࡿࡇ࡛ 6&6 ࡀ᭷ຠࡘᢠឤࡢ ᑡ࡞࠸ࡶࡢ࡞ࡾࠊ៏ᛶ⑊③ࢆᢪ࠼ࡿᝈ⪅ࡢ⏕άࡀࡼࡾᛌ㐺࡞ࡿࡇࢆᮇᚅࡋࡓ࠸ࠋ ៏ᛶ⑊③ᑐࡋ࡚࣌ࣥࢡࣜࢽࢵࢡ⛉࡛ࡣࡢࡼ࠺ 6&6 ࢆᑟධࡋ࡚࠸ࡿࠊࡲࡓࠊྛ ♫ࡢ 6&6 ࡢ≉ᚩᚋࡢᒎᮃ࡞ࡘ࠸࡚ㄝ᫂ࡍࡿࠋ 14 1-1 ୗ⫥ࡢ㞴ᛶ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ + ࢥࣝᘧ ࡢᏐࢥࣝᘧ⤒㢌☢Ẽ่⃭ࡢຠᯝẚ㍑ ΎỈኈ ᅭᑿ▱அ ⣽ぢ୍ ᚋ⸨㞝Ꮚ ᶓỤ ᙳᒣᝆ ᰡ⃝⌶ྐ ᢲ㔝ᝅ ᖹ⏣㞞அ ㈗ᓥᬕᙪ ྜྷᓠಇᶞ 㰻⸨ὒ୍ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒እ⛉Ꮫ 㜰ᏛᏛ㝔་Ꮫ⣔◊✲⛉⬻⚄⤒ᶵ⬟⏕Ꮫ ᡭ๓㝔⬻⚄⤒እ⛉⟪㠃ᕷ❧㝔⚄⤒ෆ⛉ᇸ⋢┴❧ᑠඣ་⒪ࢭࣥࢱ࣮ 1Department 2Department 3 of Neurosurgery, Osaka University Graduate School of Medicine, of Neuromodulation and Neurosurgery, Osaka University Graduate School of Medicine, Department of Neurosurgery, Otemae Hospital, 4Department of Neurology, Minoh City Hospital, 5Department of Neurosurgery, Saitama Children’s Medical Center ⚄⤒㞀ᐖᛶ⑊③࡛ࡣࠊ⑊③㒊ࡢ୍ḟ㐠ື㔝0ᑐࡍࡿ⤒㢌☢Ẽ่⃭ἲU706 ࡀ᭷ຠ࡞⒪ἲࡋ࡚▱ࡽࢀ࡚࠸ࡿࠋከタඹྠ◊✲࡛⾜ࡋࡓࡢᏐࢥࣝࡼࡿ U706ࢩ่࣒⃭ࣕࡢ↓సⅭࢡࣟࢫ࣮࢜ࣂ࣮ẚ㍑ヨ㦂࡛ࡶࠊ㞴ᛶ⚄⤒㞀ᐖᛶ⑊③ᑐ ࡋ࡚ࡢ᭷ຠᛶࡀ♧ࡉࢀࡓࠋࡋࡋࠊࡑࡢࢧࣈゎᯒ࡛ࡣୗ⫥ࡢ⑊③⩌ࡀୖ⫥ࡢ⑊③⩌ẚ ㍑ࡋࠊ᭷ຠᛶࡀప࠸ഴྥࡀぢࡽࢀࠊᡃࠎࡣୗ⫥ࡢ0ࡀẚ㍑ⓗ῝㒊⨨ࡍࡿࡇࡀཎᅉ ⪃࠼ࡓࠋࡑࡇ࡛ᡃࠎࡣࠊFP௨ୖࡢ⬻῝㒊ࢆຠ⋡ⓗࡘ㠀くⓗ่⃭ࡍࡿࡓࡵ 㛤Ⓨࡉࢀࡓ'HHS706+V\VWHP+ࢥࣝࢆᑟධࡋࡓࠋᮏ◊✲࡛ࡣࠊୗ⫥㞴ᛶ⚄⤒㞀 ᐖᛶ⑊③ࢆᢪ࠼ࡿᝈ⪅ྡᑐࡋࠊ+ࢥࣝࡼࡿᐇ่⃭ࡢᏐࢥࣝࡼࡿᐇ่⃭ࠊ ࢩ่࣒⃭ࣕࡢ✀㢮ࡢ่⃭ࡼࡿࢡࣟࢫ࣮࢜ࣂ࣮ヨ㦂ࢆ⾜ࡋࡓࠋ่⃭ࡢ㡰␒ࡣࣛࣥࢲ ࣒ࡅࠊྛ่⃭ࡣ᪥㛫㐃⥆࡛⾜ࡋࠊྛࣇ࢙࣮ࢬࡣ᪥㛫ࡢほᐹᮇ㛫ࢆタࡅࡓࠋ ᪥࠶ࡓࡾࡢ่⃭᮲௳ࡣࠊ+]ࠊ507ࠊSXOVHVࡋࡓࠋ⤖ᯝࠊࢩ่࣒⃭ࣕẚ㍑ࡋࠊ ࡢᏐࢥࣝࡼࡿU706࡛ࡣ⤫ィⓗ᭷ព࡞⤖ᯝࡣᚓࡽࢀ࡞ࡗࡓࡀࠊ+ࢥࣝࡼࡿU706 ࡛ࡣࠊ⤫ィⓗ᭷ព࡞9$6࠾ࡼࡧ6)034ࡢᨵၿࢆᚓࡿࡇࡀ࡛ࡁࡓࠋ+ࢥࣝࡼࡿU706 ࡣࠊୗ⫥ࡢ㞴ᛶ⚄⤒㞀ᐖᛶ⑊③ᑐࡍࡿ㝖③ຠᯝࢆቑᙉࡍࡿ᪂ࡋ࠸⒪ἲࡋ࡚ᮇᚅ ࡉࢀࡿࠋ 15 1-2 ⬻༞୰ᚋ⑊③ᑐࡍࡿ 6&6 ⒪ຠᯝࡢண పᐜ㔞ࢣࢱ࣑ࣥⅬ⒪ἲࢆ⏝࠸ࡓ᳨ウ すᕝὈṇ ⏿ගᙪ 㕥ᮌ ᑠᕝᙲ ᑠ➟ཎ㑥 ᒾᡭ་⛉Ꮫ⬻⚄⤒እ⛉ ᒾᡭ་⛉Ꮫ㯞㓉⛉ Prediction of the efficacy of SCS in patients with post-stroke pain Yasumasa Nishikawa1, Mitsuhiko Ohata2, Kenji Suzuki2, Akira Ogawa1, Kuniaki Ogasawara1 1 Department of Neurosurgery, Iwate Medical University 2Department of Anesthesiology, Iwate Medical University పᐜ㔞ࢣࢱ࣑ࣥⅬ⒪ἲ㸦LDK㸧ࡣ⬨㧊㟁Ẽ่⃭⒪ἲ㸦SCS㸧⾡ᚋ SCS ࡢຠᯝࢆቑ ᙉࡍࡿࡀᮇᚅ࡛ࡁࡿࡓࡵࠊ SCS ⾡ᚋࡢ⿵ຓ⒪ἲࡋ࡚⏝࠸ࡽࢀࠊ⡆౽ࡘ㐣㔞 ᢞࡢࣜࢫࢡࡶప࠸⒪ἲ࡛࠶ࡿࠋࡋࡋ࡞ࡀࡽ⬻༞୰ᚋ⑊③㸦CPSP㸧ࡢ୰ࡣ SCS ࡀ↓ຠ࡞ࡀከࡃࠊࡇࢀࡽࡢࡣ LDK ࡢే⏝࡚ࡶ༑ศ࡞㝖③ࡀᚓࡽࢀ࡞࠸ ࢆࡋࡤࡋࡤ⤒㦂ࡍࡿࠋࡑࡶࡑࡶ SCS ࡣ trial ࢆ⤒࡚ຠᯝࢆุᐃࡍࡿࡀࠊtrial ⮬యࡣ࠶ ࡿ⛬ᗘࡢくࢆຍ࠼ࡿᡭᢏ࡛࠶ࡿࡓࡵࠊSCS ࡢຠᯝࢆ⾡๓㠀くⓗண ࡍࡿࡓࡵ Drug challenge test (DCT)ࡀ⾜ࢃࢀࡿࡀከ࠸ࠋ୰࡛ࡶࢣࢱ࣑ࣥࡀ᭷ຠ࡞ࡣ SCS ࡢⰋ࠸㐺ᛂゝࢃࢀ࡚࠸ࡿࠋࡋࡋ DCT ࡣ㛗㛫ࢆせࡋࠊ㐣㔞ᢞࡢࣜࢫࢡࡸධ㝔ࢆ ᚲせࡍࡿ࡞Ỵࡋ࡚⡆౽࡞᪉ἲࡣ࠸࠼࡞࠸ࠋࡑࡇ࡛ᅇᡃࠎࡣ 5 ࡢ CPSP ࠾࠸࡚ࠊ⾡๓ LDK ࢆ⾜ࡗࡓ㝿ࡢ visual analogue scale(VAS)ࡢኚ SCS trial ᚋࡢ VAS ࡢኚࢆẚ㍑ࡍࡿࡇ࡛ࠊCPSP ࠾࠸࡚ LDK ࡀࡢ⛬ᗘ SCS ࡢ⒪ຠᯝ ண ᭷⏝࡛࠶ࡿࢆ᳨ウࡋࡓࡢ࡛ሗ࿌ࡍࡿࠋ㸺ᑐ㇟࠾ࡼࡧ᪉ἲ㸼ᑐ㇟ࡣ 2009 ᖺࡽ ᙜ㝔࡛ SCS ࢆ⾜ࡗࡓ CPSP ࡢ 5 㸦どᗋ᱾ሰ 1 ࠊ どᗋฟ⾑ 3 ࠊ ⿕Ẇฟ⾑ 1 㸧 ࠋ ධ㝔๓ࡢ VAS 㸦baseline㸧 LDK ᚋࡢ VASࠊSCS ᚋࡢ VAS ࢆẚ㍑ࡋࡓࠋ 㸺⤖ᯝ㸼baseline ẚ㍑ࡋ࡚ 5 ୰ 3 LDK ࡢຠᯝࡀㄆࡵࡽࢀࡓࠋࡇࢀࡽࡣ࡚ SCS ᚋࡢ⤖ᯝࡶⰋዲ ࡛࠶ࡗࡓࠋ୍᪉ LDK ࡢຠᯝࡀⰋ࡛࠶ࡗࡓṧࡾࡢ㸰ࡣ SCS ᚋࡶྠᵝ࡛࠶ࡗࡓࠋ௨ୖ ࡼࡾ CPSP ࠾ࡅࡿ⾡๓ࡢ LDK ࡢຠᯝ SCS ࡢ⤖ᯝࡣẚ㍑ⓗᙉ࠸┦㛵ࡀ♧ࡉ ࢀࡓࠋ 16 1-3 ୰ᯡᛶ⬻༞୰ᚋ⑊③ᑐࡍࡿ⬨㧊่⃭⒪ἲࡢຠᯝ ୖᓫ ⏣♸ బࠎ⏣ ᪂ග㜿௨Ꮚ బࠎᮌ㐩ஓ ᒸ㷂୕ಖᏊ ட⏣㞞༤ Ᏻཎ㝯㞝 ఀ㐩 ᒸᒣᏛᏛ㝔 ⬻⚄⤒እ⛉ The effect of spinal cord stimulation for central post stroke pain Takashi Agari et al. Department of Neurological Surgery, Okayama University Hospital ࠙ࡣࡌࡵࠚ୰ᯡᛶ⬻༞୰ᚋ⑊③㸦FHQWUDOSRVWVWURNHSDLQ&363㸧ࡣࠊ⬻༞୰ᝈ⪅ ࡢ 㹼㸣⛬ᗘⓎࡍࡿゝࢃࢀ࡚࠾ࡾࠊ⸆≀⒪ᢠᛶ࡛ࠊ⒪㞴ࡍࡿࡇ ࡀከ࠸ࠋ&363 ᑐࡍࡿ⬨㧊่⃭⒪ἲ㸦VSLQDOFRUGVWLPXODWLRQ6&6㸧ࡣ୍⯡᭷ຠᛶ ࡀஈࡋ࠸ࡉࢀ࡚࠸ࡿࡀࠊ6&6 ࡀ᭷ຠ࡛࠶ࡿࡶᏑᅾࡍࡿࡇࡀሗ࿌ࡉࢀ࡚࠸ࡿࠋ ࠙┠ ⓗࠚ⸆≀⒪ᢠᛶࡢ &363 ᝈ⪅ᑐࡋ࡚6&6 ࢆ⾜࠸ࠊ⒪ຠᯝ࠾ࡼࡧ⒪ⰋዲᅉᏊ ࡘ࠸᳨࡚ウࢆ⾜ࡗࡓࠋ࠙᪉ἲࠚࡣ⏨ᛶ ࠊዪᛶ ࠊᖹᆒᖺ㱋 ᡯ㸦㹼 ᡯ㸧ࠊどᗋฟ⾑ ࠊ⿕ẇฟ⾑ ࠊ ࡛࠶ࡗࡓࠋ⤒⓶ⓗ㟁ᴟᤄධࡼࡿヨ㦂่⃭ ࢆ⾜࠸ࠊ㝖③ຠᯝࡀ༑ศᚓࡽࢀࠊࡘᝈ⪅ࡀᕼᮃࡋࡓሙྜ่⃭⨨ࡢᇙࡵ㎸ࡳࢆ⾜ ࡗࡓࠋ㝖③ຠᯝࡣ 9$6㸦YLVXDODQDORJVFDOH㸧ࢆ⏝࠸࡚ホ౯ࡋࡓࠋ࠙⤖ᯝࠚヨ㦂่⃭࡛ 㸣௨ୖࡢ㝖③ຠᯝࡀᚓࡽࢀࡓࡢࡣ ୰ 㸦㸣㸧࡛࠶ࡗࡓࠋ6&6 ࢆᕼᮃࡋࡓ ่⃭⨨ᇙࡵ㎸ࡳࢆ⾜࠸ࠊ㏣㊧ᮇ㛫ᖹᆒ ࣨ᭶㸦㹼 ࣨ᭶㸧࠾࠸࡚ࠊ 㸣௨ୖࡢ㝖③ຠᯝࢆ⥔ᣢ࡛ࡁࡓࡢࡣ 㸦㸣㸧࡛࠶ࡗࡓࠋ6&6 ࡢ᭷ຠࡣ⿕ Ẇฟ⾑ᚋࡢࡀከ࠸ഴྥ࠶ࡗࡓࠋ࠙⤖ㄽࠚ&363 ᑐࡋ࡚ 6&6 ࡀ᭷ຠ࡛࠶ࡿࡀᏑ ᅾࡋ࡚࠾ࡾࠊ6&6 ࡢ㛗ᮇຠᯝࡀㄆࡵࡽࢀࡓࠋࡲࡓࠊ6&6 ࡢ᭷ຠࡣࠊ⿕ẇฟ⾑ᚋࡢ ࡀከ࠸ഴྥࡀ࠶ࡗࡓࠋ 17 1-4 ⭜㒊⬨ᰕ⟶⊃✽ᑐࡍࡿ⬨㧊่⃭⒪ἲ ❧ᒣ┿࿃ ụెዉᏊ ⏣୰ಙᙪ Ᏹ㔝Ṋྖ ₶グᛕ㝔 㯞㓉⛉࣌ࣥࢡࣜࢽࢵࢡ Spinal cord stimulation for the lumbar spinal canal stenosis Shingo Tateyama, Kanako Ikei, Nobuhiko Tanaka, Takeshi Uno Department of anesthesiology and pain clinic, Junwakai memorial hospital ⭜㒊⬨ᰕ⟶⊃✽ᑐࡍࡿ⬨㧊่⃭⒪ἲࡢሗ࿌ࡣᑡ࡞࠸ࠋᅇࠊ⭜ୗ⫥③ࢆ᭷ࡍࡿ 3 ⬨㧊่⃭⒪ἲࢆ⾜࠸ࠊⰋዲ࡞㙠③ຠᯝࡀᚓࡽࢀࡓࡢ࡛ሗ࿌ࡍࡿࠋ 3 ࡶ⭜ୗ⫥③ࠊ୧ୗ⫥ࡢࡋࡧࢀࠊ㛫Ḟᛶ㊤⾜ࡀ࠶ࡾࠊΰྜᆺࡢ⭜㒊⬨ᰕ⟶⊃✽ ⪃࠼ࡽࢀࡓࠋ③ࡳࡢᙉࡉࡣࡑࢀࡒࢀḟࡢ࠾ࡾ࡛࠶ࡗࡓࠋ 1㸧80 ṓ௦ࠊዪᛶࠋ⭜㒊 VAS20/100mmࠊୗ⫥ VAS70㹼80/100mmࠋ 2㸧80 ṓ௦ࠊ⏨ᛶࠋ⭜㒊 VAS20/100mmࠊୗ⫥ VAS90/100mmࠋ 3㸧70 ṓ௦ࠊዪᛶࠋ⭜㒊 VAS50/100mmࠊୗ⫥ VAS80㹼90/100mmࠋ 2㸧࡛ࡣࠊୗ⫥ࡢ෭ឤᒀ㞀ᐖࡶㄆࡵࡽࢀࡓࠋᒀ㞀ᐖࡣᒀᅇᩘࡀ 1 ᪥ 10 ᅇ ࡃࡽ࠸࠶ࡾࠊᒀࡢ౽ពࡶ࠶ࡗࡓࠋ㟁ᴟ࣮ࣜࢻࡣࠊࠊ⤒⓶ⓗࣃࢻ࣮ࣝࣜࢻ (lamitrode S8ࠊSt. Jude. Medical Neuromodulation Division)ࢆ⏝ࡋࡓࠋ⾜ᚋࠊ ࠊ③ࡳࡀ㍍ῶࡋࡓࠋࡲࡓࠊ 2㸧࡛ࡣୗ⫥ࡢ෭ឤᒀ㞀ᐖࡶᨵၿࡋࡓࠋࣃࢻࣝᆺ ࡢ࣮ࣜࢻࡣࠊ୍᪉ྥᛶࡢ่⃭ࡢࡓࡵࠊ⭡ቨࢆ่⃭ࡍࡿࡇ࡞ࡃࠊ⭜⫼㒊ࡢ่⃭ࡀྍ⬟ ࡛࠶ࡿࠋࣃࢻࣝᆺࡢ࣮ࣜࢻࡣࠊ ࠕ⤒⓶ⓗࣃࢻ࣮ࣝࣜࢻࠖࠕእ⛉ⓗࣃࢻ࣮ࣝࣜࢻࠖࡢ 2 ✀㢮࠶ࡿࡀࠊ⤒⓶ⓗࣃࢻ࣮ࣝࣜࢻࡢሙྜࠊ᳝ᘪษ㝖ࡍࡿࡇ࡞ࡃ␃⨨ࡍࡿࡇࡀ࡛ࡁࠊ くࡶᑡ࡞࠸ࠋ⤒⓶ⓗࣃࢻ࣮ࣝࣜࢻࡢ⏝ࡼࡾࠊ⭜㒊ୗ⫥༑ศ࡞่⃭ࡀᒆࡁࠊ③ ࡳࢆ㍍ῶࡉࡏࡿࡇࡀ࡛ࡁࡓࠋࡉࡽࠊ่⃭ࡼࡾᮎᲈ⾑ὶ㞀ᐖࡢᨵၿཬࡧᒀᶵ⬟ࡢ ࣂࣛࣥࢫࡢᨵၿࡶࡘ࡞ࡀࡗࡓ⪃࠼ࡽࢀࡓࠋ 18 1-5 ୕ཫ⚄⤒③ᑐࡍࡿ & ᮎᲈ⚄⤒㔝㙀㏻㟁่⃭ࡢヨࡳ ▱ஂࡍࡳࢀ 㩗⃝⪽ Ḉᗞ㝧 ⟃Ἴᢏ⾡Ꮫಖ⛉Ꮫ㒊㝃ᒓᮾす་Ꮫ⤫ྜ་⒪ࢭࣥࢱ࣮ ⟃Ἴᢏ⾡Ꮫಖ⛉Ꮫ㒊ಖᏛ⛉㙀⅍Ꮫᑓᨷ C2 peripheral nerve field stimulation using electroacupuncture for the patients with trigeminal neuralgia. Report of 3 cases. Sumire Chiku1, Satoshi Ayuzawa1,2, Hinata Sakuraba1 1Center 2 for Integrative Medicine, Tsukuba University of Technology. Course of Acupuncture and Moxibustion, Department of Health, Faculty of Health Sciences, Tsukuba University of Technology ࠙ࡣࡌࡵࠚ㏆ᖺࠊ៏ᛶ㢌③ᑐࡋ C2 ᮎᲈ⚄⤒㔝่⃭(C2PNfS)ࢆ⾜࠸ዌຌࡋࡓࡀ ሗ࿌ࡉࢀ࡚࠸ࡿࠋ୍᪉ࠊᡃࠎࡣ㙀ࢆ⏝࠸ࡓ C2PNfS(EAP-C2PNfS)ࢆ⾜࠸୍ᐃࡢຠᯝࢆ ሗ࿌ࡋ࡚ࡁࡓࠋᅇࠊ୕ཫ⚄⤒③ᝈ⪅ᑐࡋྠᵝࡢ⒪ࢆヨࡳ≧ࡢᨵၿࡀᚓࡽࢀࡓ ࢆ⤒㦂ࡋࡓࡓࡵሗ࿌ࡍࡿࠋ ࠙ࠚ 1㸸49 ṓ⏨ᛶࠋX-2 ᖺྑ㢦㠃③Ⓨࠋཎᅉ᫂ࡢࡓࡵ࢝ࣝࣂ࣐ࢮࣆࣥࢆ ฎ᪉ࡉࢀࡿࡀ⸆⑈ࠊ⫢㞀ᐖࡢࡓࡵ୰ṆࠋMRI ࡛⚄⤒ᅽ㏕ࡀᣦࡉࢀ࡚࠸ࡿࠋVAS 21 ࡽ⒪ 4 ᅇ⤊ᚋࡣ 4 ࡞ࡾࠊADL ᨭ㞀ࡣ࡞࠸ࠋ 2㸸84 ṓዪᛶࠋX-16 ᖺࡼࡾ ྑ㢦㠃③ⓎࠋX-8 ᖺ MVD ⾜ࡋࠊⴭຠࡋࡓࡀ 2 ᖺᚋⓎࠋMRI ࡛ⴭ᫂࡞⚄⤒ᅽ㏕ࡣ ㄆࡵࡽࢀ࡞࠸ࠋVAS 88 ࡽࠊ4 ᅇ⒪⤊ᚋࡣ 43ࠊࡑࡢᚋࡶ⒪ࢆ⥅⥆ࡋ࡚⾜࠸ VAS 10 ⛬ᗘୗࡀࡗ࡚࠸ࡿࠋ࢝ࣝࣂ࣐ࢮࣆࣥ 1 ᪥ᖹᆒ᭹⸆㔞ࡣ 300mgЍ50mg ࡞ࡗࡓࠋ 3㸸60 ṓ⏨ᛶࠋX-1 ᖺᕥୖṑ⫗③࡛Ⓨࡋᕥ㢦㠃ᗈࡀࡿࠋṑ⛉࡛ࡣ␗ᖖ࡞ࡃ㝔 ⪥㰯ဗႃ⛉࡛୕ཫ⚄⤒③デ᩿ࠋ࢝ࣝࣂ࣐ࢮࣆࣥࢆෆ᭹ࡋ࡚࠸ࡿࡀᝏഴྥࠋయෆ㔠ᒓ ࡢࡓࡵ MRI ࡣࢀࡎ⚄⤒ᅽ㏕ࡢ᭷↓ࡣ᫂ࠋVAS 83 ࡛ࠊ4 ᅇ⒪⤊ࡣ③ࡳࡢ⛬ ᗘ࣭ㄏⓎᅉᏊࡀῶᑡࠋ࢝ࣝࣂ࣐ࢮࣆࣥ 1 ᪥ᖹᆒ᭹⸆㔞ࡣ 357mgЍ266mg ࡞ࡗࡓࠋ ࠙⪃ᐹࠚᅇࡢ࡛ࡣ᭹⸆ࢆࡣ୰Ṇ࡛ࡁ࡚࠸࡞࠸ࡀࠊEAP-C2PNfSࡢే⏝࡛᭹ ⸆㔞ࢆῶᑡࡉࡏࠊࡘ᭷ຠ࡞⑊③ࢥࣥࢺ࣮ࣟࣝࡀᚓࡽࢀࡿྍ⬟ᛶࡀ♧၀ࡉࢀࡓࠋ୕ཫ⚄ ⤒⬨㧊㊰᰾ࢆࡋ࡚ࠊୖࡢ࣐࣌ࣥࢺࣜࢵࢡࢫࡢឤసࢆᢚไࡉࡏࡓྍ⬟ᛶࡀ⪃࠼ࡽࢀ ࡿࠋ 19 1-6 ៏ᛶ㢌③࣭㢁㒊③ᑐࡍࡿࣁ࣮ࣥ࢞ᑕࡢ᪂ࡓ࡞ᛂ⏝ࡢ᳨ウ ᪫ 㞝ኈ బ⸨ ᮍ▱ ⏣୰ ᑑ▱ ୰ᮧ ᣅே ᝆẼ Ლᮏ ⿱அ 㔠ἑ⬻⚄⤒እ⛉㝔 ⬻⚄⤒እ⛉㸪 㟁Ẽ㏻ಙᏛ ⥲ྜሗᏛ㸪 ῭⏕ᯇᒣ㝔 Clinical application of hanger reflex to patients with chronic headache and neck pain Takashi Asahi1, Michi Sato2, Takuto Nakamura2, Yuki Kon2, Kazunori Tanaka3, Hiroyuki Kajimoto2 1 Department of Neurosurgery Kanazawa Neurosurgical Hospital 2Department of Informatics, University of Electro-Communications 3 Department of Neurosurgery, Saiseikai Matsuyama Hospital 㢦ࢆṇ㠃ྥࡅࡓ≧ែ࡛ࠊ㔪㔠ࡢࣁ࣮ࣥ࢞ࢆᶓྥࡁࡋ࡚๓ഃ㢌㒊ࢆᅽ㏕ࡍࡿࡼ࠺ ╔ࡍࡿࠊ㢌ࡀᅇ㌿ࡋ࡚ࡋࡲ࠺ࠋࡇࡢ⌧㇟ࡣࠊࣁ࣮ࣥ࢞ᑕࡋ࡚ሗ࿌ࡉࢀ࡚࠸ࡿࠋࢃ ࢀࢃࢀࡣࠊࣁ࣮ࣥ࢞ᑕࢆ㢁㒊ࢪࢫࢺࢽࡢ⒪ᛂ⏝ࡋࠊຠᯝࢆ☜ㄆࡋ࡚࠸ࡿࠋࡲࡓࠊ ᅇ᪕᪉ྥࡔࡅ࡛࡞ࡃࠊ๓ᚋ᪉ྥࡢࣁ࣮ࣥ࢞ᑕࡶㄏⓎ࡛ࡁࠊᑓ⏝ࢹࣂࢫࡼࡗ࡚᭷ຠ ࡀぢࡽࢀ࡚࠸ࡿࠋ୍᪉ࠊ៏ᛶ㢌③㢁㒊ࢪࢫࢺࢽࢆకࡗ࡚࠸ࡿࡀ࠶ࡿ࠸ࢃࢀ࡚ ࠸ࡿࠋᅇࠊࢃࢀࢃࢀࡣࠊ㢁㒊ྍືᇦไ㝈ࢆక࠺㢌③࣭㢁㒊ᝈ⪅ࣁ࣮ࣥ࢞ᑕㄏⓎࢹ ࣂࢫࢆ╔ࡋࠊຠᯝࢆ☜ㄆࡋࡓࠋ㸯㸸 ṓ⏨ᛶࠋᚋ⦪㠎ᖏ㦵⾡ᚋ࡛≉ᕥഃ ࡢ㢁㒊ྍືᇦไ㝈ࢆకࡗ࡚࠸ࡓࠋᅇ᪕ࢱࣉࡢࢹࣂࢫࢆ╔ࡍࡿࡇ࡛ࠊ㤳ࡢືࡁࡢ ᨵၿࡀぢࡽࢀࡓࠋ⒪๓ᚋ࡛ࠊ7:6756SDUW,ЍࠊSDUW,,,Ѝ ᨵၿࡀぢࡽࢀ ࡓࠋ 㸸 ṓ⏨ᛶࠋ㏻ᨾࡼࡿ㢁㧊ᦆയᚋ㢁㒊ࡢᚋᒅࡢྍືᇦไ㝈㢌③࣭ 㢁㒊③ࢆッ࠼࡚࠸ࡓࠋ๓ᚋࢱࣉࡢࢹࣂࢫࢆ╔ᚋࠊྍືᇦࡢⴭ᫂࡞ᨵၿ㢌③ࡢ㍍ ῶࢆㄆࡵࡓࠋ╔ᚋࡣࠊ7:6756SDUW,ЍࠊSDUWϪЍ ᨵၿࡀぢࡽࢀࡓࠋ㢌③ ᝈ⪅ᑐࡍࡿ࣎ࢶࣜࢾࢫ⒪ἲࡢሗ࿌ࡀࡉࢀ࡚࠸ࡿࡀࠊᮏ㑥࡛ࡣಖ㝤デ⒪࡛ㄆࡵࡽࢀ࡚࠸ ࡞࠸ࠋᮏ⒪ἲࡣࠊ㢌③࣭㢁㒊③ᑐࡍࡿᏳ౯࡛㠀くⓗ࡞⒪ἲ࡞ࡿྍ⬟ᛶࡀ࠶ࡿࠋ ᚋࡣࠊከタ࡛ࡢ᳨ウࢆ⾜ࡗ࡚࠸ࡃணᐃ࡛࠶ࡿࠋ 20 2-1 㢁㒊ࢪࢫࢺࢽᑐࡍࡿ⤒㢌☢Ẽ่⃭ἲࡢຠᯝ ᮧᒸ ⠊⿱ 㔜᳃ ⛱ ᳃ᒸᇶᾈ ᰗᕝࣜࣁࣅࣜࢸ࣮ࢩࣙࣥ㝔 ⬻⚄⤒እ⛉ ஂ␃⡿Ꮫ་Ꮫ㒊 ⬻⚄⤒እ⛉ The effect of 1Hz-repetitive transcranial magnetic stimulation on 10 patients with cervical dystonia Norihiro Muraoka1,2, Minoru Shigemori1, Motohiro Morioka2 1Division 2 of Neurosurgery, Yanagawa Rehabilitation Hospital Departments of Neurosurgery, Kurume University School of Medicine ࠙ࡣࡌࡵࠚࢪࢫࢺࢽᑐࡍࡿ⤒㢌☢Ẽ่⃭ἲUHSHWLWLYHWUDQVFUDQLDO PDJQHWLFVWLPXODWLRQ㸸U706ࡣ᭩②ࢆ୰ᚰሗ࿌ࡀከࡃࡳࡽࢀ࡚࠸ࡿࡀࠊࡑࡢ ᭷ຠᛶࡣᚲࡎࡋࡶ☜❧ࡉࢀࡓࡶࡢ࡛ࡣ࡞࠸ࠋᅇ㞴ᛶࡢ㢁㒊ࢪࢫࢺࢽᑐࡍࡿ U706 ࡢ⮫ᗋⓗຠᯝ᭷⏝ᛶࡘ࠸᳨࡚ウࡋࡓࠋ ࠙ᑐ㇟ࠚᑐ㇟ࡣ⸆≀⒪ࡸ࣎ࢶࣜࢾࢫẘ⣲➽ὀ⒪ἲ➼࡛ᨵၿࡀᅔ㞴࡞㢁㒊ࢪࢫࢺࢽᝈ ⪅ ࡛࠶ࡿࠋࡢෆヂࡣ࠸ࢃࡺࡿᩳ㢁 ࠊ࢘ࣝࢫᛶ⬻⅖ᚋ ࠊᢠ⢭⚄⸆ ⒪ࡼࡿ㐜Ⓨᛶࢪࢫࢺࢽ ࡛࠶ࡾࠊࢪࢫࢺࢽ㐠ືࡀṧᏑࡋ࡚࠸ࡿࠋ ࠙᪉ἲࠚ่⃭㒊ࡣࠊᙧࢥ࡛ࣝ㢁㒊➽ࡀグ㘓ࡉࢀࡿ㐠ື⓶㉁㔝㡿ᇦタ⨨ࡋࡓࠋ่ ⃭ᙉᗘࡣᏳ㟼㐠ື㜈್ࡢ ࠊ ่⃭㢖ᗘࡣ +]ࠊ ่⃭ᅇᩘࡣ୧ഃ ᅇ㐌 ᅇࡢ FRRO ࡛⾜ࡋࡓࠋホ౯ἲࡣ 7RURQWR:HVWHUQ6SDVPRGLF7RUWLFROOLV5DWLQJ6FDOHࢆ⏝࠸ ࡚ U706 ๓ᚋࡢ▷ᮇⓗホ౯ࢆ⾜ࡗࡓࠋ ࠙⤖ᯝ࣭ࡲࡵࠚ୧ഃ๓㢌㒊ࡢ +]U706 ࡣ▷ᮇ㛫࡛࠶ࡗࡓࡀࠊࢪࢫࢺࢽ㐠ືࢆయ ࡋࡓ㢁㒊ࢪࢫࢺࢽࡢᨵၿຠᯝⓗ࡛࠶ࡗࡓࠋᩳ㢁ࡔࡅ࡛࡞ࡃࠊ㐜Ⓨᛶࢪࢫࢺࢽ➼ ࡶྠᵝࡢຠᯝࡀぢࡽࢀࡓࠋ୧ഃ๓㢌㒊ࡢ +]U706 ࡣ㏆ᖺ㢁㒊ࢪࢫࢺࢽࡢ᭷ຠᛶ ࡀሗ࿌ࡉࢀ࡚࠸ࡿ '%6 ࡢຠᯝ㢮ఝࡋ࡚࠾ࡾࠊ'%6 ࡢຠᯝண ᙺ❧ࡘྍ⬟ᛶࡀ࠶ࡿࠋ 21 2-2 ⬻༞୰ᚋᡓᑐࡍࡿ⬻⓶㉁㐠ື㔝่⃭ࡢຠᯝ 㸸⬻῝㒊่⃭⒪ἲࡢẚ㍑ࡽ ᒣᮏ㝯 Ώ㎶ ゅග୍㑻 ῲᩄᶞ ຍ⣡ ᑠᯘ୍ኴ ᓥ⚽つ ῝㇂ぶ ྜྷ㔝⠜⥴ ∦ᒣᐜ୍ ᪥ᮏᏛ⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝⚄⤒እ⛉Ꮫศ㔝 MCS for post-stroke tremor: Comparison with DBS therapy Takamitsu Yamamoto, Mitsuru Watanabe, Koichiro Sumi, Toshiki Obuchi, Toshikazu Kano, Kazutaka Kobayashi, Hideki Oshima, Chikashi Fukaya, Atsuo Yoshino, Yoichi Katayama Divisions of Applied System Neuroscience and Neurosurgery, Department of Neurological Surgery, Nihon University School of Medicine ࠙┠ⓗࠚ ᡓࡢไᚚࡣࠊ どᗋ Vim/Vop ᰾࡞ࡽࡧ subthalamus ࡢ่⃭ࡀ᭷⏝࡛࠶ࡾࠊ ⬻⓶㉁㐠ື㔝่⃭ࡢຠᯝࡘ࠸࡚ࡶሗ࿌ࡉࢀ࡚࠸ࡿࠋ⬻⓶㉁㐠ື㔝่⃭ࡼࡿ⬻༞ ୰ᚋᡓᑐࡍࡿຠᯝࡘ࠸࡚ࠊ⬻῝㒊่⃭⒪ἲࡢẚ㍑ࢆ⾜ࡗࡓࠋ ࠙᪉ἲࠚ⬻༞୰ᚋ⑊③⬻༞୰ᚋᡓࢆྜేࡋࠊ⑊③ᡓࡢ⒪ࢆ┠ⓗ⬻⓶㉁㐠 ື㔝่⃭ࢆ⾜ࡗࡓ࠾࠸࡚ࠊ่⃭㛤ጞࡼࡿᡓࡢᢚไຠᯝࡘ࠸᳨࡚ウࡍࡿ ࡶࠊ㛗ᮇⓗ࡞่⃭ࡼࡿᡓࡢᢚไຠᯝࡘ࠸࡚ࡶ᳨ウࡋࡓࠋࡲࡓࠊ⬻༞୰ᚋᡓ ᑐࡍࡿ㛗ᮇⓗ࡞⬻῝㒊่⃭ࡢຠᯝࡢẚ㍑ࢆ⾜ࡗࡓࠋ ࠙⤖ᯝࠚ่⃭㛤ጞࡼࡿᡓࡢᢚไຠᯝࡘ࠸࡚ࡣࠊ⬻⓶㉁㐠ື㔝่⃭ࡼࡾࡶ⬻῝㒊 ่⃭࡛ᡓࡢᢚไຠᯝࡣⴭ࡛᫂࠶ࡗࡓࠋ㛗ᮇⓗ࡞่⃭ࡢຠᯝ࡛ࡣࠊ⬻⓶㉁㐠ື㔝่⃭ ࢆ⾜ࡗࡓ࡛ࡣ่⃭ࢆ୰Ṇࡋ࡚ࡶᡓࢫࢥࡢᨵၿࡀᣢ⥆ࡋࡓࠋ୍᪉ࠊ⬻῝㒊่⃭⒪ ἲ࡛ࡣ㛗ᮇࡢ่⃭ࢆ⾜ࡗ࡚ࡶࠊࡇࡢࡼ࠺࡞ຠᯝࡣㄆࡵ࡞ࡗࡓࠋࡲࡓࠊ⬻⓶㉁㐠ື㔝 ่⃭ᚋ่⃭ࢆ୰Ṇࡋ࡚ࡶᡓࢫࢥࡢᨵၿࡀᣢ⥆ࡋࡓ࡛ࡣࠊ่⃭㛤ጞ๓ẚ㍑ࡋ ࡚②⦰ࡢ⛬ᗘࡀቑຍࡋ࡚࠸ࡓࠋ ࠙⪃ᐹࠚ⬻༞୰ᚋ⑊③ᑐࡍࡿ⬻⓶㉁㐠ື㔝่⃭࡛ࡣࠊ୍᪥ࡢ่⃭㛫ࡀ㛗ࡃ࡞ࡿ ②⦰ࡀቑᝏࡍࡿࡇࢆሗ࿌ࡋࡓ(Stereotact Funct Neurosurg 2011)ࠋ⬻⓶㉁㐠ື㔝 ่⃭࡛ࠊ่⃭ࢆ୰Ṇࡋ࡚ࡶᡓࢫࢥࡢᨵၿࡀᣢ⥆ࡋࡓཎᅉࡋ࡚ࡣࠊ②⦰ࡢ⛬ᗘኚ ࢆㄆࡵࡓᐇࡀ㔜せ⪃࠼ࡿࠋ 22 2-3 ࣃ࣮࢟ࣥࢯࣥᑐࡍࡿ 671'%6㸸 㛗ᮇⓗ᭷ຠ࡞ࡢࡣ࠸࡞ࡿ㸽 ῝㇂ぶ Ώ㎶ ຍ⣡ ᑠᯘ୍ኴ ᓥ⚽つ ྜྷ㔝⠜⥴ ᒣᮏ㝯 ᪥ᮏᏛ⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝⚄⤒እ⛉Ꮫศ㔝 STN-DBS for PD treatment: What are the expected long-term beneficial effects on patients? Chikashi Fukyaya, Mitsuru Watanabe, Toshikazu Kano, Kazutaka Kobayashi, Hideki Oshima, Atsuo Yoshino, Takamitsu Yoshino Divisions of Applied System Neuroscience and Neurosurgery, Department of Neurological Surgery, Nihon University School of Medicine ࠙┠ⓗࠚPD ⒪࠾࠸࡚ DBS ࡀ㔜せ࡞⒪㑅ᢥ⫥ࡢ୍ࡘ࡛࠶ࡿࡇࡣࠊࡇࡇᩘᖺࡢ◊ ✲ࡽ᫂ࡽ࡛࠶ࡿࠋࡋࡋࠊࡶࡕࢁࢇ࡚ࡢ DBS ࡀᚲせ࡞ࢃࡅ࡛ࡣ࡞ࡃࠊ ࠺࠸ࡗࡓ DBS ࢆ✚ᴟⓗᑟධࡍࡁ᫂ࡽ࡛࡞࠸Ⅼࡶᑡ࡞ࡃ࡞࠸ࠋᮏ◊✲࡛ ࡣࠊ㛗ᮇⓗ࡞ ADL ࡢ⮬❧࠸࠺どⅬࡽࠊ༑ศ࡞ᡭ⾡┈ࢆᚓࡿࡇࡀ࡛ࡁࡿࡢࡣࠊ ࠸࡞ࡿ࡛࠶ࡿࢆ᳨ウࡋࡓࠋ ࠙᪉ἲࠚᙜ㝔࡚ᡭ⾡ࢆ⾜࠸⾡ᚋ 5 ᖺ௨ୖࡢ⤒㐣ࢆ᭷ࡋࠊSchwab & England scale ࡀ off 80 ࣏ࣥࢺ௨ୖࡢ A ⩌ (n=33) 80 ࣏ࣥࢺᮍ‶ࡢ B ⩌ (n=33) ศࡅࠊⓎ ᖺ㱋ࠊ⨯ᮇ㛫ࠊᡭ⾡ᖺ㱋ࠊ⾡๓ࡢෆ᭹≧ἣࠊ⾡๓ࡢ UPDRSࠊHDSࠊMMSE ࡞ ࡘ࠸࡚ࡑࡢ┦㐪Ⅼࢆ᳨ウࡋࡓࠋ2 ⩌㛫ࡢẚ㍑ࡣ Mann-Whitney-U-test ࢆ⏝࠸ p㸺 0.05 ࡚᭷ពุ᩿ࡋࡓࠋ ࠙⤖ᯝ࠾ࡼࡧ⥲ᣓࠚA ⩌ B ⩌࡛᭷ពᕪࡢㄆࡵࡽࢀࡓࡶࡢࡣࠊⓎᖺ㱋㸦p㸺0.05㸧 ᡭ⾡ᖺ㱋㸦p㸺0.01㸧࡛࠶ࡗࡓࠋ⨯ᮇ㛫ࡣ᭷ពᕪࡣ᳨ฟࡉࢀ࡞ࡗࡓࠋMMSE ࡶ᭷ពᕪࡀㄆࡵࡽࢀࡓ㸦p㸺0.01㸧 ࠋ௨ୖࡼࡾⓎᖺ㱋ᡭ⾡ᖺ㱋ࡀࡶⱝࡃࠊㄆ▱ ᶵ⬟ࡢపୗࡋ࡚࠸࡞࠸ࠊ⾡ᚋ㛗ᮇⓗ࡞ ADL ࡢ⮬❧ࡀᮇᚅ࡛ࡁࡿࡇࡀ᫂ࡽ ࡞ࡗࡓࠋࡇ࠺ࡋࡓ࠾࠸࡚ࡣࠊ༑ศ࡞ᡭ⾡┈ࡀᮇᚅ࡛ࡁࠊDBS ࡀ PD ⒪࠾࠸ ࡚ᯝࡓࡍᙺࡣࡁ࠸⪃࠼ࡽࢀࡓࠋ 23 2-4 ៏ᛶ⬻༞୰ᚋࡢ㐠ື㞀ᐖᑐࡍࡿ⬨㧊่⃭⒪ἲ す㔝ඞᐶ ᒣཱྀ༟ ᕷ❧ゅ㤋⥲ྜ㝔⬻⚄⤒እ⛉ Spinal cord stimulation may enhances motor recovery in chronic stroke Kastuhiro Nishino, Suguru Yamaguchi Neurosurgical Service, Kakunodate City General Hospital 㸦ࡣࡌࡵ㸧⬨㧊่⃭⒪ἲ(SCS)ࡣ㞴ᛶ⑊③ࡢ᭷⏝࡞ᡭẁ࡛࠶ࡿࡀࠊ᭱㏆ࠊ⬨㧊ᦆയ ࡔࡅ࡛࡞ࡃ⬻ᦆയࡶ⬨㧊 ࡀ⬻ᶵ⬟㞀ᐖࢆ௦ൾࡍࡿྍ⬟ᛶࡀ♧၀ࡉࢀࠊspinal brain ࠸࠺ᴫᛕࡀᥦၐࡉࢀ࡚࠸ࡿࠋ ᅇࠊᡃࠎࡣ mesh socks 㟁ᴟࡢ⤖ᯝࢆࡶ⬻ ༞୰ࡢ SCS ࡛ୗ⫥㐠ືᶵ⬟ࡀᨵၿࡍࡿࢆ᳨ウࡋࡓࠋ 㸦ᑐ㇟ࠊ᪉ἲ㸧㸵ࡢ⬻༞୰㸦ᗈ ⠊࡞⓶㉁㞀ᐖࢆ㝖ࡃ⬻ฟ⾑ 4 ࠊ⬻᱾ሰ㸰㸪ࡃࡶ⭷ୗฟ⾑㸯㸪ᖺ㱋㸸54Ѹ84 ṓ㸪 ⏨ᛶࠊⓎᚋ 1Ѹ24 ᭶㸪ᖹᆒ㸴᭶㸧࡛㐠ື③ࡳక࠺㧗ᗘࡢ②ᛶ㐠ື㯞⑷ࢆ࿊ࡍࡿ ࡛ࠊSCS㸦ឤぬ㜈್௨ୗ㸪ឤぬ㜈್㸪㐠ື㜈್௨ୗ㸧ࡢ㐠ື㞀ᐖࡢᙳ㡪ࡘ࠸᳨࡚ ウࡋࡓࠋ่⃭㟁ᴟࡣ㸵Ѹ10 ᪥ࡢヨ㦂่⃭ࡢᚋࠊC2-C7 ࡲࡓࡣ Th10-L㸰ṇ୰ࡲࡓࡣഐ ṇ୰࠾࠸ࡓࠋ(⤖ᯝ) 1)㢕㧊่⃭ࡢࡳࡢୖ⫥ࡢᅇ 㸱㸭㸲㸦㸧 ࠊୗ⫥ࡢᅇ 㸯㸭㸲 㸰㸧ୗ㒊⬚㧊/⭜㧊่⃭࡛ୗ⫥ࡢᅇ 㸱㸭㸴㸦⤖ㄽ㸧㸯㸧dual SCS ࡣ่⃭㟁ᴟࡢ㑅ᢥ ่⃭ᙉᗘࡢ㑅ᢥ࡛ࠊṧᏑࡍࡿ㐠ືᶵ⬟ࡢホ౯ࡀྍ⬟ᛮࢃࢀࡿࠋ㸰㸧⬻༞୰ᚋࡢ㐠ື 㯞⑷ࡀ⬨㧊่⃭࡛ᨵၿࡉࢀࡿࡀ࠶ࡿࠋ 24 3-1 どᗋୗ᰾่⃭⾡ᚋࡢㄆ▱ᶵ⬟ࡢపୗ ୰㔝┤ᶞ ᐑෆṇᬕ ຍ⸨ኳ⨾ ㏆␥Ꮫ་Ꮫ㒊⬻⚄⤒እ⛉ Naoki Nakano, Masaharu Miyauchi, Amami Kato Department of Neurosurgery, Kinki University ࣃ࣮࢟ࣥࢯࣥᑐࡍࡿどᗋୗ᰾่⃭⾡ᚋࡢㄆ▱ᶵ⬟ࡢపୗࡣᵝࠎ࡛࠶ࡿࠋࣃ࣮࢟ࣥ ࢯࣥ⮬యࡢኚ࡛ࡶㄆ▱ࡀฟ⌧ࡋ࡚ࡃࡿࡇࡶ࠶ࡿࠋࣃ࣮࢟ࣥࢯࣥࡢ⬻῝㒊่⃭ 㟁ᴟ⾡㸦㹂㹀㹑㸧ᚋ㸰ᖺ࡛ࠊㄆ▱ᶵ⬟ࡢపୗࢆࡳࡓࡘ࠸࡚⯆࠶ࡿ⤒㐣ࢆ♧ࡋࡓ ࡢ࡛ࠊሗ࿌ࡍࡿࠋ 㸵㸲ṓࠊ⏨ᛶࠋ㸳㸴ṓࠊྑᡭࡢࡋࡧࢀ࡚ࠊ㏆་ᩚᙧእ⛉ཷデࠋࡑࡢᚋࠊྑᡭࡢࡩ ࡿ࠼ࡽࠊ⚄⤒ෆ⛉ࢆཷデࠋࡸࡀ࡚ࣃ࣮࢟ࣥࢯࣥデ᩿ࡉࢀࠊᢠࣃ࣮࢟ࣥࢯࣥ⸆ࢆ 㛤ጞࡉࢀ࡚ࡁࡓࠋྑᡭࡢᡓࡢቑᙉࠊ࢜ࣥ࢜ࣇ⌧㇟ࠊࢪࢫ࢟ࢿࢪࡀฟ⌧ࡋࠊ㸴㸷ṓࠊ どᗋୗ᰾่⃭⾡ࢆ⾜ࡋࡓࠋ⾜๓ࡢ 0LQLPHQWDOVWDWHH[DPLQDWLRQ006(ࡣ Ⅼ ࡛࠶ࡗࡓࠋ'%6 ᚋࠊ㐠ືᶵ⬟ࡢᨵၿࢆࡳࡓࠋ⮬Ⓨᛶࡢపୗࡀᚎࠎฟ⌧ࡋࠊ㸰ᖺᚋࠊㄆ ▱⬟ຊࡢపୗ࡚ࠊ006( 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ࡀእ⛉ᡭ⾡୍⯡࢞ࢻࣛࣥࢆ⟇ᐃࡋ࡚࠸ࡿࠋࡇࢀࡲ่࡛⃭ࢩࢫࢸ࣒ᇙタ⾡ 㸦DBS ➼㸧࠾ࡅࡿᣦ㔪ࢆ♧ࡋࡓࡶࡢࡣ࡞࠸ࡀࠊᙜ⛉࡛ࡣ SSI ࡢண㜵ࡘ࠸࡚ CDC ࡢ࢞ࢻࣛࣥ‽ᣐ࡛ࡁࡿࡼ࠺ດࡵ࡚ࡁࡓࠋDBS ➼࠾ࡅࡿ SSI ࡢࣜࢫࢡࣇࢡࢱ ࣮ࠊᢠ⳦⸆ࡢ⏝᪉ἲࡘ࠸᳨࡚ウࡋࡓ⤖ᯝࢆሗ࿌ࡍࡿࠋ ࠙ᑐ㇟ཬࡧ᪉ἲࠚ1997 ᖺ 7 ᭶ࡽ 2014 ᖺ 2 ᭶ࡢ㛫ࣃ࣮࢟ࣥࢯࣥᑐࡋ࡚ DBS ࠾ࡼࡧ IPG ⾡ࢆ⾜ࡗࡓࡢ࠺ࡕࠊ⾑ᾮ᳨ᰝࢹ࣮ࢱࠊᢠ⳦⸆ࡢᢞᒚṔࠊ SSI ࡢ᭷↓ࡀ࢝ࣝࢸୖࡢグ㍕࡛☜ㄆࡉࢀࡓ 549 ᡭ⾡ࢆᑐ㇟ࡋࡓࠋ᳨ウ㡯┠ࡣᖺ㱋ࠊ ᛶูࠊ⢾ᒀࡢ᭷↓ࠊ㝶⾑⢾ࠊHbA1cࠊ⾡๓ධ㝔᪥ᩘࠊᡭ⾡㛫ࠊᢠ⳦⸆ᢞ≧ἣ➼ ࡘ࠸᳨࡚ウࡋࡓࠋSSI ࡢุᐃࡣ CDC ࡢ࢞ࢻࣛࣥᚑࡗࡓࠋ ࠙⤖ᯝࠚDBS 383 ᡭ⾡୰ 9 ࡀ SSI ุᐃࡉࢀࠊឤᰁ⋡ࡣ 2.3 %࡛࠶ࡗࡓࠋSSI Ⓨ ⏕᭷ពᕪࢆㄆࡵࡓ㡯┠ࡣ⢾ᒀࡢ᭷↓ࠊ㝶⾑⢾ࠊ⓶ᝈࡢ᭷↓ࠊ⾡୰ᢠ⳦⸆ᢞ ࡢ᭷↓࡛࠶ࡗࡓࠋ⾡ᚋᢠ⳦⸆ࡢᢞࡣ SSI ࡢண㜵↓㛵ಀ࡛࠶ࡗࡓࠋIPG ⾡ࡘ ࠸࡚ࡶྠᵝࡢ⤖ᯝ࡛࠶ࡗࡓࠋ ࠙⪃ᐹࠚ2014 ᖺ 4 ᭶ CDC ࡢ࢞ࢻࣛࣥᨵゞ∧ࡢ draft ࡀබ㛤ࡉࢀࡓࡀࠊDBS ➼ࡘ࠸࡚ࡣゝཬࡉࢀ࡚࠸࡞࠸ࠋࡋࡋࠊᮏ◊✲ࡢ⤖ᯝࡽࠊDBS ➼ࡶእ⛉୍⯡ྠ ᵝࡢ࢞ࢻࣛࣥࢆ㐺⏝ࡍࡿࡇࡀ࡛ࡁࡿ⪃࠼ࡽࢀࡓࠋ 26 3-3 ぬ㓰ࢧࣝ⭡ഃ㐠ື๓㔝ࢽ࣮ࣗࣟࣥࡢ⇕่⃭ᑐࡍࡿᛂ⟅ ᾏ㔝ಇᖹ ᒾ⏣ᖾ୍ ᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ Neuronal response to thermal stimuli in monkey ventral premotor cortex Shumpei Unno, Koichi Iwata Department of Physiology, School of Dentistry, Nihon University ୍ḟ㐠ື㔝ࡸ๓㢌๓㔝ࠊ㐠ື๓㔝ᑐࡍࡿ⤒㢌☢Ẽ่⃭ἲࡼࡿ③ࡳࡢ㍍ῶຠᯝ ࡣ⧞ࡾ㏉ࡋሗ࿌ࡉࢀ࡚࠸ࡿࡀࠊࡑࡢ࣓࢝ࢽࢬ࣒ࡣ౫↛࡛᫂࠶ࡿࠋᮏ◊✲࡛ࡣࠊ ᗘឤ ぬ࠾ࡼࡧ③ぬཷᐜ࠾ࡅࡿ๓㢌ⴥࡢᙺࢆ᫂ࡽࡍࡿࡓࡵࠊ2 㢌ࡢࢽ࣍ࣥࢨࣝ⇕ ่⃭ࡢ ᗘኚࢆᘚูࡍࡿㄢ㢟ࢆカ⦎ࡋࠊ๓㢌ⴥࡼࡾ㢦㠃㡿ᇦࡢゐぬ่⃭ᛂ⟅ࡍࡿ ࢽ࣮ࣗࣟࣥࡢㄢ㢟㐙⾜୰ࡢάືࢆグ㘓ࡋࡓࠋࢧࣝࡢཱྀ㧨㒊タ⨨ࡋࡓ⇕่⃭⏝ࣉ࣮ࣟࣈ ࡼࡾ⇕่⃭ࢆ࠼ࡓࠋㄢ㢟࡛ࡣࢧࣝࡀ࣎ࢱࣥࢆᢲࡍࣉ࣮ࣟࣈ ᗘࡀ 35Υࡽ 45-47Υ ୖ᪼ࡍࡿ㸦T1 ᮇ㛫㸧 ࠋ࣎ࢱࣥࢆᢲࡋ⥆ࡅࡿ ᗘࡀࡉࡽ 0.2-0.8Υୖ᪼ࡋ㸦T2 ᮇ㛫㸧 ࠊ ࢧࣝࡀࡇࡢ ᗘኚࢆ᳨ฟࡋ㸱⛊௨ෆ࣎ࢱࣥࢆ㞳ࡏࡤሗ㓘ࡋ࡚ࢪ࣮ࣗࢫࡀ࠼ࡽ ࢀࡿࠋカ⦎ᡂᚋࠊࢧࣝ๓㢌ⴥࡼࡾㄢ㢟㐙⾜୰ࡢ༢୍ࢽ࣮ࣗࣟࣥάືࢆグ㘓ࡋࡓࠋ୍㒊 ࡢࢽ࣮ࣗࣟࣥࡣ T1 T2 ࡢ୧᪉ࡢ ᗘኚᛂ⟅ࡋࡓࡀࠊከࡃࡢࢽ࣮ࣗࣟࣥࡣ T1 ࡲࡓ ࡣ T2 ࡢࡕࡽ୍᪉ࡢ ᗘኚࡢࡳᛂ⟅ࡋࡓࠋࡲࡓ T2 ᮇ㛫ࡢࢽ࣮ࣗࣟࣥάືࡢᛂ ⟅₯ࡣࠊࢧࣝࡢ࣎ࢱࣥ㞳ࡋࡢᛂ㛫┦㛵ࡋ࡚࠸ࡓࠋ㸯㢌ࡢࢧ࡛ࣝ⬻⤌⧊ᶆᮏࡢస 〇ࢆ⾜࠸グ㘓㒊ࢆỴᐃࡋࡓࡇࢁࠊ⇕่⃭ᛂ⟅ࡍࡿࢽ࣮ࣗࣟࣥࡣ⭡ഃ㐠ື๓㔝㝈 ᒁࡋ࡚Ꮡᅾࡍࡿࡇࡀศࡗࡓࠋࡇࢀࡽࡢ⤖ᯝࡣ⭡ഃ㐠ື๓㔝ࢽ࣮ࣗࣟࣥࡢάືࡀ⇕่ ⃭ᘚูㄢ㢟࠾ࡅࡿᚤᑠ࡞ ᗘኚࡢ᳨ฟ㔜せ࡞ᙺࢆᯝࡓࡋ࡚࠸ࡿࡇࢆ♧၀ࡋ ࡚࠸ࡿࠋ 27 ࠙᪥ᮏࢽ࣮ࣗࣟࢹ࣮ࣗࣞࢩࣙࣥᏛཧຍド࡛ࠊཧຍࡍࡿࡇࡀ࡛ࡁࡲࡍࠋࠚ ➨ ᅇ ࠕ③ࡳࡢ⚄⤒⛉Ꮫ◊✲ࠖ ⚄⏣ᕝ࣮࣡ࢡࢩࣙࢵࣉࡢࡈෆ ᣏၨ 㝧ࡢೃࠊඛ⏕᪉ࡣ┈ࠎࡈΎ⚈ࡢࡇ࠾ࡧ⏦ࡋୖࡆࡲࡍࠋ ࡉ࡚ࠊࡇࡢᗘ➨ 20 ᅇࠕ③ࡳࡢ⚄⤒⛉Ꮫ◊✲ࠖ⚄⏣ᕝ࣮࣡ࢡࢩࣙࢵࣉࢆୗグࡢ㏻ࡾ㛤ദࡢ㐠ࡧ ࡞ࡾࡲࡋࡓࠋࡈከᛁ୰ࡢࡇࢁㄔᜍ⦰࡛ࡍࡀࠊఱ༞ࡈฟᖍ㈷ࡾࡲࡍࡼ࠺ࡈෆ⏦ࡋୖࡆࡲࡍࠋ ᩗල ③ࡳࡢ⚄⤒⛉Ꮫ◊✲ ௦⾲ୡヰே ᡞ⏣ ୍㞝 ڦ᪥ ᖹᡂ 27 ᖺ 4 ᭶ 25 ᪥㸦ᅵ㸧17:00㹼19:00 ڦሙ 㒔ᕷࢭࣥࢱ࣮࣍ࢸࣝ ࢜ࣜ࢜ࣥ ᮾி㒔༓௦⏣༊ᖹἙ⏫ 2-4-1 TEL 03㸦3265㸧8211 ڦཧຍ㈝ 1,000 ڦᮏඛ❧ࡗ࡚㛤ദࡉࢀࡿ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛࡢཧຍドࢆ࠾ᣢࡕࡢ᪉ࡣ↓ᩱ ࡛ࡍ ڦᆅୗ㕲 ᭷ᴦ⏫⥺ ࠕ㯜⏫㥐ࠖ ༙ⶶ㛛᪉㠃 1 ␒ฟཱྀࡼࡾᚐṌ 4 ศ ڦᆅୗ㕲 ᭷ᴦ⏫⥺࣭༙ⶶ㛛⥺ ࠕỌ⏣⏫㥐ࠖ4 ␒࣭5 ␒ฟཱྀࡼࡾᚐṌ 4 ศ ڦᆅୗ㕲 ༡⥺ ࠕỌ⏣⏫㥐ࠖ9 ␒ฟཱྀࡼࡾᚐṌ 3 ศ ڦᆅୗ㕲 ࡢෆ⥺࣭㖟ᗙ⥺ ࠕ㉥ᆏぢ㝃㥐ࠖD ฟཱྀࡼࡾᚐṌ 8 ศ ڦJR ୰ኸ⥺ ࠕᅄ㇂㥐ࠖ㯜⏫ฟཱྀࡼࡾᚐṌ 14 ศ ڦ㒔ࣂࢫ ᖹἙ⏫ 2 ┠ࠕ㒔ᕷࢭࣥࢱ࣮๓ࠖୗ㌴ 㸦᪂ᶫ㥐㹼ᕷࣨ㇂㥐㹼ᑠᶫ㌴ᗜ๓㸧 ڦ㤳㒔㧗㏿ 㟘ࣨ㛵ฟཱྀࡼࡾ 5 ศ 28 ࠙ࣉࣟࢢ࣒ࣛࠚ 1㸬㛤ᣵᣜ 㛗ᓮᏛᏛ㝔་ṑ⸆Ꮫ⥲ྜ◊✲⛉⏕యሗ⛉Ꮫ 㸦17:00㹼17:05㸧 ᡞ⏣ ୍㞝 ඛ⏕ -------------------------------------------------------------------------------------------------------------------- 2㸬ヰ㢟ᥦ౪ 㸦17:05㹼17:20㸧 ࠕࣜࣇࣞࢵࢡࢫ㘄ࡘ࠸࡚ࠖ Meiji Seika ࣇ࣐ࣝᰴᘧ♫ࢧ࢚ࣥࢸࣇࢵࢡࢧ࣏࣮ࢺ㒊 -------------------------------------------------------------------------------------------------------------------- 3㸬≉ูㅮ₇Ϩ ᗙ㛗 ᪥ᮏᏛṑᏛ㒊⏕⌮Ꮫㅮᗙ 㸦17:20㹼18:10㸧 ᒾ⏣ ᖾ୍ ඛ⏕ ࠕ753 ࢳࣕࢿࣝࡼࡿᐖཷᐜᶵᵓࠖ ⮬↛⛉Ꮫ◊✲ᶵᵓᒸᓮ⤫ྜࣂ࢜ࢧ࢚ࣥࢫࢭࣥࢱ࣮⏕⎔ቃ㡿ᇦ⣽⬊⏕⌮㒊㛛 ᐩỌ ┿⍆ ඛ⏕ -------------------------------------------------------------------------------------------------------------------- 㸲㸬≉ูㅮ₇ϩ ᗙ㛗 ᪥ᮏᏛ་Ꮫ㒊⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝 㸦18:10㹼19:00㸧 ῝㇂ ぶ ඛ⏕ ࠕ⬻༞୰ᚋ⑊③ࡢ⒪ࠖ ᪥ᮏᏛ་Ꮫ㒊⬻⚄⤒እ⛉Ꮫ⣔ᛂ⏝ࢩࢫࢸ࣒⚄⤒⛉Ꮫศ㔝 ᒣᮏ 㝯 ඛ⏕ -------------------------------------------------------------------------------------------------------------------࣮ͤ࣡ࢡࢩࣙࢵࣉ⤊ᚋࠊ㒔ᕷࢭࣥࢱ࣮࣍ࢸ࡚ࣝሗࢆணᐃࡋ࡚࠾ࡾࡲࡍࠋ ᑦࠊᮏඛ❧ࡗ࡚ྠࡌሙ࡚ࠕ᪥ᮏࢽ࣮ࣗࣟࣔࢹ࣮ࣗࣞࢩࣙࣥᏛࠖࡀ㛤ദࡉࢀࡲ ࡍࡢ࡛ࠊྜࢃࡏ࡚ࡈཧຍࡃࡔࡉ࠸ࠋ ඹദ㸸③ࡳࡢ⚄⤒⛉Ꮫ◊✲ Meiji Seika ࣇ࣐ࣝᰴᘧ♫ 29
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