NUTR*4320

DEPARTMENT OF HUMAN HEALTH AND NUTRITIONAL SCIENCES
NUTR*4320
NUTRITION AND THE METABOLIC CONTROL OF DISEASE
WINTER – 2015
INSTRUCTOR: Dr. Jennifer Monk
Phone: 824-4210 ext 56967,
Email: [email protected]
Office hours: Tues/Thurs, 4-5 PM in ALEX 200
*additional review sessions will be held prior to the midterm and final exam
CLASS MEETING TIME AND PLACE:
ALEX 200 Tues/Thurs 2:30-3:50 PM
OBJECTIVES:
This course deals with metabolic diseases most of which can be described in biochemical terms.
These anomalies produce symptoms, or structural abnormalities, which impair the fitness, quality of
life or potentially lead to death of the individual. The attention is focused on the mechanism(s)
thought to participate in disease development, the affected metabolic pathways and the clinical
manifestations which lead to disease symptoms. The role of nutrition both in prevention of disease
development and as part of the therapeutic strategy to diminish symptoms or reverse pathology are
examined along with classical treatment strategies involving lifestyle modification, drugs, and
supplements provided as nutraceuticals or functional foods.
GRADING SCHEME:
Form of
Assessment
Midterm Exam
Weight of
Assessment
30% or 50%*
Final Exam
50% or 30%*
Assignment 1
10%
Assignment 2
10%
Due Date of
Assessment
Thursday
February 12, 2015
TBA
Course
Content/Activity
First half of the
course only
Last half of the
course only
Thursday
February 5, 2015
Tuesday March
26, 2015
First half of the
course only
Last half of the
course only
* The exam with the better grade will be weighted 50% and the exam with the lowest grade will be
weighted 30%. Exam questions will consist of multiple choice and some short answer questions.
ASSIGNMENTS:
Each assignment is due 1 week prior to the Midterm exam (Assignment 1) and the last lecture
(Assignment 2). The assignments are designed to achieve the following outcomes i) encourage
students to begin reviewing the lecture material in advance of the examinations, ii) to promote
stronger understanding and retention of critical lecture material and iii) serve as a class generated
sample practice exam (posted on courselink).
Assignment 1 – Due: February 5, 2015
GTA – George Payne: [email protected]
Assignment 2 – Due: March 5, 2015
GTA – Daniel Pyc: [email protected]
For both Assignment 1 and Assignment 2 students are required to review the lecture material and
generate 4 multiple choice questions (with possible answers A, B, C or D). There must be only ONE
possible correct answer for each question and the answer for each question must be provided.
Students must also indicate in point form why the other 3 possible answers provided are incorrect. A
hard copy of each assignment is due AT THE START OF CLASS on the due date above; however,
students are encouraged to complete and submit their assignments prior to the due date. Each student
is also required to EMAIL their assignment to the designated Teaching Assistant so that their
questions can be anonymously posted on courselink to provide sample questions to be utilized for
study purposes by the rest of the class.
**Please make sure you put “NUTR4320 Assignment” as the subject line in your email!!
GTA OFFICE HOURS:
Graduate Teaching Assistants will hold office hours every MONDAY 8:30-9:30am in ANNU room
338.
COURSE RESOURCES:
Course Readings: There are NO required textbooks for this course. "
Outlines of lecture notes will be available on the CourseLink website. I will do my best to post
outlines of lecture notes in a timely manner (within a minimum of 24 hours prior to class). The
intention of the lecture notes is NOT to provide the student with a complete set of notes, but to
provide a guide or outline of the lecture to provide students with a better opportunity to understand
the lecture content as it is presented. Students are encouraged to review the lecture material prior to
class and to seek assistance during GTA office hours or after class.
OUTLINE OF COURSE CONTENT:
INTRODUCTION TO NUTRITION AND METABOLISM
- The genetic material, DNA, RNA, and protein structure/function
- Defining some important terms: Familial inheritance, somatic mutation, alleles
- Allergy and intolerance
ABNORMALITIES OF CARBOHYDRATE AND AMINO ACID METABOLISM
- Lactase deficiency/lactose intolerance
- Celiac disease
- Hyperphenylalaninemia (PKU and non-PKU)
ABNORMALITIES IN BRAIN FUNCTION
- Attention Deficit Hyperactivity Disorder
- Major Depression
DISEASES WITH MULTIPLE METABOLIC DEFECTS
- Osteoporosis
- Cancer
IMPORTANT DATES:
Tuesday, January 6, 2015- First Lecture
Thursday February 5, 2015 – Assignment 1 DUE IN CLASS + email a copy to the GTA
Thursday, February 12, 2015 – in class MIDTERM examination
February 16-20, 2015 – Reading Week – no classes
Friday, March 6, 2015– Fortieth class day. Last day to drop this course.
Thursday, March 26, 2015– Assignment 2 DUE IN CLASS + email a copy to the GTA
Thursday, April 2, 2015 – Last Lecture
April 10, 2015 – FINAL EXAM – Location TBA

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