Dental implants in maxillofacial prosthodontics An asset in head and neck cancer and Sjögren’s syndrome patients Anke Korfage The research presented in this thesis was performed at the Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, the Netherlands. Sponsoring was requested and granted only after completion of the research and writing of the thesis. Publication of this thesis was generously supported by: Nederlandse Vereniging voor Gnathologie en Prothetische Tandheelkunde (www.nvgpt.nl) Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie (www.nvmka.nl) Nederlandse Vereniging voor Orale Implantologie (www.nvoi.nl) Tandtechnisch en Maxillofaciaal Laboratorium Gerrit van Dijk, Groningen Straumann B.V. (www.straumann.nl) Nobel Biocare Benelux B.V. (www.nobelbiocare.nl) Excent tandtechniek (www.excent.nl) Noord Negentig accountants en belastingadviseurs (www.noordnegentig.nl) Rijksuniversiteit Groningen (www.rug.nl) Orthodontiepraktijk Verstraaten (www.orthodontieassen.nl) Lay-out: sgaar groningen Printing: Drukkerij van der Eems, Heerenveen Publisher: Anke Korfage, Groningen ISBN: 978-90-367-7785-8 ISBN e-pub: 978-90-367-7784-1 Copyright: Anke Korfage, 2015 All rights reserved. No part of this publication may be reported or transmitted, in any form or by any means, without permission of the author. Dental implants in maxillofacial prosthodontics An asset in head and neck cancer and Sjögren’s syndrome patients Proefschrift ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen op gezag van de rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op woensdag 29 april 2015 om 16.15 uur door Anke Korfage geboren op 17 maart 1978 te Delfzijl Promotores Prof. dr. A. Vissink Prof. dr. G.M. Raghoebar Prof. dr. J.L.N. Roodenburg Copromotor Dr. H. Reintsema Beoordelingscommissie Prof. dr. H.J.A. Meijer Prof. dr. E.A.J.M. Schulten Prof. dr. M.A.W. Merkx Paranimfen Drs. I. Korfage Dr. E.M. Janknegt-Biadaskiewicz Contents Chapter 1 Introduction and aim of the study 9 Chapter 2 Mandibular implants installed in edentulous oral cancer patients during ablative tumour surgery 17 Chapter 2.1 A 5-year follow-up of oral functioning and quality of life in oral cancer patients with implant-retained mandibular overdentures Head Neck 2011; 33: 831-839 19 Chapter 2.2 Benefits of dental implants installed during ablative tumour surgery in oral cancer patients: a prospective 5-year clinical trial Clin Oral Implants Res 2010; 21: 971-979 37 Chapter 2.3 Overdentures on primary mandibular implants in oral cancer patients: an up to 14 years cohort Br J Oral Maxillofac Surg 2014; 52: 798-805 57 Chapter 2.4 Mandibular implants placed during ablative tumour surgery—which patients can benefit? Int J Oral Maxillofac Surg 2013; 42:1037-1039 73 Chapter 3 79 Oral rehabilitation with maxillary implants in childhood rhabdomyosarcoma patients Support Care Cancer 2011;19:1477-1480 Chapter 4 Recommendations for implant-retained nasal prostheses after ablative tumour surgery: minimal surgical aftercare, high implant survival and satisfied patients (accepted for publication in Head Neck) 91 Chapter 5 Dental implants: a good treatment option in patients with Sjögren’s syndrome (submitted) 107 Chapter 6 General discussion and conclusions 123 Chapter 7 Summary133 Chapter 8 Samenvatting141 Dankwoord149 Curriculum Vitae155 8
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