information and workshop agenda

ANIMAL FEEDING STUDIES AND IN VITRO STUDIES
IN GMO RISK ASSESSMENT
2nd Stakeholder Workshop
19-20 MAY 2014
European Commission, Madou tower,
1 Place Madouplein, Brussels, Belgium
DRAFT AGENDA
Context
In the course of the European Commission funded research project GRACE (GMO Risk
Assessment and Communication of Evidence) 90-day animal feeding trials, animal studies
with an extended time frame as well as analytical, in vitro and in silico studies are conducted
on GM maize in order to evaluate comparatively their use in GMO risk assessment. In the
stakeholder consultations in December 2012 (first workshop and written consultation) and
December 2013 (written consultation only) planning-stage issues relevant to these studies
were discussed. The comments received at the occasion of that consultation were addressed
when finalising the study plans. Comments and GRACE-team responses are available at
http://www.grace-fp7.eu/content/reports-study-plans-consultation-documents.
This 2nd stakeholder workshop will provide an opportunity to review the results obtained so far
and to discuss their interpretation. The status of approaches alternative to animal testing will
also be presented. The consultation is planned at a pivotal moment in the project, allowing
adjustments to the final set of studies.
To prepare for the consultation, documentation will be provided in advance of the meeting to
registered parties and on the GRACE website. Written comments, also from interested parties
not able to attend, are welcome until 2 weeks after the stakeholder workshop.
Objective
The aim of this workshop is to
1) discuss the results of the 90-day studies with GM maize MON810 performed as part of
the GRACE project;
2) update on GRACE activities on alternative and complementary studies to animal
feeding studies (in vitro, in silico, and analytical studies), and
3) provide information on follow-up and spin-off activities.
Agenda 15 April 2014
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Anticipated Output
The feed-back received in the course of the stakeholder consultation will be summarised in a
report drafted by the GRACE team and circulated to all participants to ensure that it accurately
and fairly reflects their views and comments. A final report will then be prepared based on
comments received and published on the GRACE website.
Attendance
This consultation is open to all stakeholders interested in the safety and impacts of GMOs.
This includes but is not limited to GMO risk assessors, risk managers, representatives of all
relevant sectors of industry, farmer organisations, civil society organisations and academia.
Anyone interested in attending is kindly invited to register by sending name, first name,
affiliation and contact address via e-mail to [email protected] before 30 April
2014. Attendance is free of charge but registration before the deadline is required
according to security rules at Commission buildings. Registration after the deadline will not be
possible.
GRACE Contacts
Dr. Greet Smets
(Workshop Coordinator)
PERSEUS b.v.b.a
Technologiepark 3
B-9052 Zwijnaarde, Belgium
e-mail: [email protected]
Prof. Joachim Schiemann (Overall Project Coordinator)
Julius Kühn-Institut (JKI), Federal Research Centre
for Cultivated Plants
Erwin-Baur-Strasse 27
06484 Quedlinburg, Germany
e-mail: [email protected]
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This workshop is funded by the European Commission 7 Framework Programme in the context of
the large collaborative project GRACE (Grant Agreement No 311957). For more information on
GRACE: http://www.grace-fp7.eu/.
Agenda 15 April 2014
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Travel information
Venue: European Commission, Madou tower, 1 Place Madouplein, Brussels, Belgium
From the airport
• By taxi: a taxi from the airport to Madou will cost about 36€.
• By public transport: At the airport take a train to Brussels till Brussel-Centraal/BruxellesCentral (8.50€). Take metro line 1 direction Stokkel/Stockel or line 5 direction HerrmannDebroux to 2 stops further (Kunst-Wet/Arts-Loi). Change lines: line 2 or line 6 direction
Elisabeth. Get off the next stop at Madou. Alternatively, take a bus at the central station.
Bus 63 direction Duiveltjes or Bus 29 direction Hof ten Berg. The 4th stop is Madou.
From train station Brussel-Zuid/Bruxelles-Midi:
• Take metro line 2 or line 6 direction Elisabeth. Get off 7 stops further at Madou.
Agenda 15 April 2014
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2nd GRACE Stakeholder Workshop on Animal Feeding Studies
and In Vitro Studies in GMO Risk Assessment
Agenda 19 May 2014
11:30
12:30
Registration
Possibility for light lunch at canteen (at own expense)
INTRODUCTION
Welcome
Patrick Rüdelsheim, Perseus,
Ghent, Belgium
Update on the GRACE project by the Coordinator
Joachim Schiemann, Institute for Biosafety in Plant Biotechnology,
Julius Kühn Institut, Quedlinburg, Germany
Stakeholder and User Involvement in GRACE/ Introduction to the Workshop
Armin Spök, IFZ-Inter-University Research Centre
for Technology, Work and Culture, Graz, Austria
Implementation of the feeding studies: requirements and constraints
Ralf Wilhelm, Institute for Biosafety in Plant Biotechnology,
Julius Kühn Institut, Quedlinburg, Germany
Discussion
13:45
90-DAY FEEDING STUDIES – DESIGN AND ANALYSIS
Chair: Armin Spök
General design and analysis
Pablo Steinberg, University of Veterinary Medicine,
Hannover, Germany
Maize cultivation
María Plá, Center for Research in Agricultural Genomics (CRAG)
Barcelona, Spain
Discussion
15:00
Coffee break
Agenda 15 April 2014
Agenda 19 May 2014 - continued
15:30
Analysis of plant material and diets
Gijs Kleter, RIKILT-Institute of Food Safety,
Wageningen University and Research Centre, The Netherlands
Test facility, periodic observations and necropsy
Dagmar Zeljenková, Department of Toxicology,
Slovak Medical University, Bratislava, Slovakia
Haematology and biochemistry
Jana Tulinska, Department of Toxicology,
Slovak Medical University, Bratislava, Slovakia
Histopathology
Pablo Steinberg, University of Veterinary Medicine,
Hannover, Germany
Discussion
18:00
Adjourn Day 1
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Agenda 15 April 2014
Agenda 20 May 2014
08:30
08:45
Recapitulation day 1/ launch day 2
Patrick Rüdelsheim, Perseus, Ghent, Belgium
ALTERNATIVE APPROACHES
Chair: Gijs Kleter
In vitro studies
Ralf Einspanier, Freie Universität, Berlin, Germany
Omics studies on plant material
Esther Kok, RIKILT-Institute of Food Safety,
Wageningen University and Research Centre, The Netherlands
Longitudinal metabolomic studies
Karine Adel-Patient, Unité INRA d'Immuno-Allergie Alimentaire,
Gif-sur-Yvette, France
Discussion
10:15
Coffee break
10:45
PROSPECTS AND NETWORKING
Chair: Joachim Schiemann
Further studies
Ralf Wilhelm, Institute for Biosafety in Plant Biotechnology,
Julius Kühn Institut, Quedlinburg, Germany
CADIMA
Christian Kohl, Institute for Biosafety in Plant Biotechnology,
Julius Kühn Institut, Quedlinburg, Germany
G-TwYST
Pablo Steinberg, University of Veterinary Medicine,
Hannover, Germany
Discussion
12:15
GENERAL DISCUSSION
Chair: Armin Spök
General discussion
Next steps and closing remarks
13:45
End of workshop
Possibility for light lunch at canteen (at own expense)
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