PRODUCT BULLETIN Prime Pac PRRS+ ™ PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VACCINE Modified Live Virus For the vaccination of healthy swine as an aid in the reduction of clinical signs of reproductive disease in female breeding age swine and respiratory disease in pigs 3-4 weeks of age and older due to PRRS virus (PRRSv). Advantages ■■ Protects against the reproductive and respiratory forms of PRRSv. ■■ Vaccine virus was demonstrated to be safe following vaccination. ■■ Aids in the reduction of infection following a PRRSv challenge. ■■ In sows and gilts: Helps reduce the duration of viremia –– More viable piglets are born –– Lowers piglet mortality through 7 weeks of age –– Fewer clinical reproductive abnormalities (large mummies, stillborns and death within 24 hours) –– Reduces viremia in piglets born to vaccinated sows and gilts In growing pigs: –– Reduces clinical signs of disease (clinical scores and body temperature) –– Reduces viremia and histopathologic lesions –– ■■ ■■ 4-month duration of immunity (DOI) provides long-lasting protection. ■■ Another example of Merck Swine 360° that uses a unique Discover-Solve-Support process to bring science-based solutions that are best for your animals and best for your business. Prime Pac™ PRRS+ 12 X 100ml BULK PAC #143281 For sows and gilts: 600 doses – 2-mL dose For piglets: 1200 doses – 1-mL dose Prime Pac™ PRRS+ 100ml #147699 For sows and gilts: 50 doses – 2-mL dose For piglets: 100 doses – 1-mL dose Prime Pac™ PRRS+ 20ml #143123 For sows and gilts: 10 doses – 2-mL dose For piglets: 20 doses – 1-mL dose Prime Pac™ PRRS+ PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VACCINE Modified Live Virus DESCRIPTION CAUTION: Prime Pac™PRRS+ is a live vaccine containing a modified porcine reproductive and respiratory syndrome (PRRS) virus which has been grown to high titer in an approved cell line, blended with stabilizing agents and lyophilized. At the time of use the lyophilized vaccine is rehydrated with the accompanying diluent. 1. T his vaccine is not intended for use in pregnant swine or for use in boars. The vaccine virus is derived from a field virus. The virus was attenuated by serial passage in cell culture but shown to remain immunogenic in vaccination and challenge studies. No evidence of reversion to virulence was detected in back passage studies conducted in susceptible animals. 3. For animal use only. Do not vaccinate within 21 days before slaughter. INDICATIONS For the vaccination of healthy swine as an aid in the reduction of clinical signs of reproductive disease in female breeding age swine and respiratory disease in pigs 3-4 weeks of age and older due to PRRS virus. ADMINISTRATION/DOSAGE Sows and Gilts: Inject a single 2-mL dose intramuscularly (IM) 3 to 6 weeks prior to each breeding. Piglets: Inject a single 1-mL dose (IM) at 3-4 weeks of age or older. The duration of immunity is at least four months. PREPARATION OF THE VACCINE 1. Do not rehydrate the vaccine until ready for use. 2. Mix only one set of vials at a time and use entire contents promptly after rehydration. 3. Using a sterile transfer needle, transfer the entire contents of sterile diluent into the bottle of freeze-dried vaccine and shake the combined vaccine and diluent to suspend evenly. The vaccine is now ready for use. 2. Vaccine virus can shed and spread to nonvaccinated contact animals and may result in seroconversion of the entire herd. 4. Store at 2˚-7˚C (35˚-45˚F). Protect the vaccine from excessive light and heat. 5. U se aseptic technique and only sterile needles and syringes to inject the vaccine. Syringes and needles may be sterilized by boiling for 15 to 20 minutes. Do NOT disinfect with chemicals since they destroy the PRRS vaccine virus. Do not transfer the vaccine to other containers. 6. U se entire contents when first opened. Burn containers and all unused contents. 7. D o not dilute the vaccine or otherwise attempt to stretch the dosage. 8. If allergic response occurs, administer epinephrine. PRESERVATIVE: Gentamicin Intervet Inc. Omaha, Nebraska 68103 USA U.S. Vet Lic. No. 165A 1-800-521-5767 READ AND FOLLOW LABEL DIRECTIONS U.S. Veterinary License No. 165A FOR VETERINARY USE ONLY 556 Morris Avenue | Summit, NJ 07901 | merck-animal-health-usa.com | 800-521-5767 Copyright © 2014 Intervet Inc., doing business as Merck Animal Health, a subsidiary of Merck & Co., Inc. All rights reserved. SW-PRRS-PS-036-1 (09-14)