Schedule for Vaccination:

Schedule for Vaccination:
Age
Birth
1 Month
2 Months
3 Months
4 Months
6 Months
7 Months
7 – 9 Months
12 Months
12 – 15 Months
15 Months
18 Months
1 ½ Years – 2 Years
2 Years
4 – 5 Years
5 Years
10 Years
>10 Years
Vaccine
Hep B 1
OPV 1
BCG
Hep B 2
OPV 2
DTaP1 / DTwP1
IPV 1
Combined
Hib 1
OPV 3
Rotavirus 1
PCV 1
DTaP2 / DTwP2
IPV 2
Combined
Hib 2
OPV 4
Rotavirus 2
PCV 2
DTaP3 / DTwP3
IPV 3
Combined
Hib 3
OPV 5
PCV 3
Hep B3
Influenza - A 1
Influenza - A 2
Measles Vaccine
Hep A 1
Chicken Pox (Varicella)
MMR 1
Hep A 2
DTaP / DTWP
IPV Booster
Booster 1
Hib Booster
OPV
PCV Booster
Typhoid Vaccine
DTaP / DTWP Booster 2
OPV
MMR 2
Typhoid Vaccine
Tdap
DT
HPV 1 (0 month)
HPV 2 (2 months)
HPV 3 (6 months)
Information about Vaccines:
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BCG
OPV
Hep B
DPwT
DTaP
Hib
Combined Vaccines
Rota Virus
Pneumococcal Conjugate Vaccine (PCV)
Influenza
Measels
Hep A
Chicken Pox
MMR
Typhoid
HPV
BCG ( bacillus calmette guerin).
BCG is for prevention of childhood Tuberculosis. Especially complications of tuberculosis such
as meningitis & biliary tuberculosis.
BCG vaccine is given on the upper part of the left shoulder. A small nodule appears 4 – 8 weeks
after the vaccine. It may soften or occasionally ulcerate and then leave a small scar. Presence of
the scar indicates effective vaccination. No mark appears after 2 months, please inform your
doctor. Revaccination may be considered.
This vaccine provides 50 to 80 % efficacy against serious tubercular infection like military and
tubercular meningitis. And 50 % against pulmonary tubercular infections..
Schedule- This vaccine is given at birth. If not given at birth catch up vaccination can be given up
to 5 years of age..
This is an intradermal vaccine. Given on the left shoulder at the insertion of deltoid muscle..
Dose- 0.1 ml.
It is a freeze dried vaccine diluted just before the administration.It can be stored in freeze at 2
to 8 degrees for 6 hours..
Side effects- there are no side effects. The local reaction occurs starting with a papule (2 to 4
weeks) after the administration. A scar develops at 6 to 12 weeks.
Contraindications- immunocompromised patients, who are on immunosuppressive therapy,
hypogammaglobulinemia, malignancy.
BCG can be given to a child born to HIV positive mother.
BRAND- tubervac, serum institute of India.
OPV (ORAL POLIO VACCINE)
Even though there is no polio in the United States - or, in fact, in the Western hemisphere - it is
still common in some parts of the world. And still not eradicated from India. A single infection
brought into the country by someone travelling from one of these regions could lead to a polio
epidemic all over again if we were not protected. That is why polio vaccinations are still given.
Polio is caused by a virus that lives in the throat and intestinal tract. It is spread through contact
with the bowel movements of an infected person (for instance, by changing diapers).
Some children who get polio don't feel ill at all. For others, polio simply feels like a cold, with
symptoms appearing about six to'20 days after exposure. Sometimes these children will also
feel some pain and stiffness in their neck, back and legs, but this soon goes away.
However, some children who get polio become paralyzed and lose the use of their muscles. This
is called paralytic polio. Paralytic polio can start like a common cold, but often with severe
muscle pain. Paralysis usually comes within the first week. Most often, it affects the child's legs,
but sometimes it affects other muscles, including those that control breathing.
Some children recover from their paralysis, but many will be permanently disabled. There is no
treatment for polio, and some children die from it. Polio is most contagious from about seven
to 10 days before symptoms appear until about seven to 10 days afterward.
There are two types of polio vaccine: inactivated (killed) polio vaccine (IPV), which is an
injection; and live oral polio vaccine (OPV), which is a liquid that is swallowed.
Global polio eradication was started in 1988 using OPV vaccine.
OPV is a trivalent vaccine. It consist of suspension of attenuated poliovirus of types 1,2,and
3.OPV was developed by sabin. Licensed in 1961 as monovalent and 1963 as trivalent OPV.
This vaccine can be stored at 2 to 8 degrees for 6 months. 1 to 3 days at room temperature.
but the vaccine must reach the outreach facility at 2 to 8 degrees in vaccine carrier to maintain
its efficacy.
Dose- 2 drops orally..( bas do boond)
Multiple doses of OPV are necessary for development of 90 to 95 % immune response.
IAP has recommended the administration of OPV at birth, then 3 doses at 6, 10, 14 weeks. And
then 2 additional doses at 16 to 18 months and 5 years.
Side effects- risk of vaccine associated paralytic polio (VAPP) is estimated in 1 per 4.6 million
doses, which is very rare.
Contraindication- OPV is contraindicated in immunodeficient patient
(humoral immunodeficiency), and their household contacts.
OPV is recommended to be given in all children less than 5 yrs during the pulse polio
(campaigns conducted by govt of India)
What is pulse immunization?
Immunization against a particular disease mimics infection against the causative microbe in
inoculated individual without the risk of the disease. But only the immunized children are
benefitted. However when increasing number of children gets the vaccination the transmission
of the infectious agent is retarded, this is herd effect. When large proportion of susceptible
children are vaccinated in a short period of time, an epidemic is stimulated. The consequent
herd effect develops, resulting in break of transmission of the agent. Thus, the repetitive
campaigns are done at annual intervals..
OPV OR IPV ?
Without OPV polio eradication may have been impossible..
 Easy to administer.
 Still needed where wild polio virus is circulating.
 Effective in controlling outbreaks.
 Provides contact immunity.
Without IPV polio eradication is certainly impossible..
 To prevent virus circulation
 To facilitate detection of re-emerging polio virus.
IPV
IPV (inactivated polio vaccine.)
IPV is formaldehyde killed poliovirus grown in monkey kidney cell/human diploid cells.
It is stored at 2 to 8 degrees.
Dose- 0.5 ml intramuscular.
Site- mid lateral aspect of thigh in infants and children.
Schedule- from 2 months, 3 successive injections of 0.5 ml should be administered at the
interval of 1 or 2 months.( 6, 10, 14 weeks )
It is also available in combination form with DPT which also has same schedule and same
effectiveness as well. so we can reduce one prick to your baby!!
For booster, 4 the dose is administered 1 year after the 3 rd dose.
A booster is given every 5 years in children and adolescents.
Side effect- pain, erythema, induration, moderate transient fever. Very rarely edema,
lymphadenopathy, hypersensitivity reaction.
Precautions: There are several reasons a doctor might want to delay giving a
Child an IPV vaccination, or not give it at all:
• A child who is known to have a severe allergy to the antibiotics
Neomycin, streptomycin or polymyxin B should not get IPV.
• A child who has had a severe allergic reaction after a dose of
IPV should not get another dose.
• A child who has a moderate or severe illness on the day an
IPV (or any) vaccination is scheduled should probably delay
The vaccination until he or she has recovered.
BRAND- IMOVAX POLIO BY SANOFI PASTEUR.
HEP B VACCINE (HEPATITIS B VACCINE)
Hepatitis B is a disease that affects the liver. It is one of several hepatitis diseases (for example,
hepatitis A and hepatitis C).
These are caused by different germs, but are similar in that they all affect the liver.
Hepatitis B is caused by a virus. Some people who are infected with the hepatitis B virus never
feel sick. Others have symptoms that might last for several weeks. Those symptoms can
include:
• Loss of appetite and tiredness
• Pain in muscles, joints or stomach
• Diarrhoea or vomiting
• Yellow skin or eyes
This is called acute hepatitis B. Some people never recover from hepatitis B. They develop what
is called chronic (long-term) hepatitis B virus infection. They might not look or feel sick, but they
will probably carry the hepatitis B virus in their blood for the rest of their lives, and they can
infect other people.
Many of these chronically infected people will suffer from serious health problems, such as
cirrhosis (scarring of the liver) or liver cancer. In fact, the hepatitis B virus causes most of the
liver cancer in the world. Hepatitis B is a major cause of liver cancer, and hepatitis B vaccine can
prevent the disease. Therefore, the hepatitis B vaccine is the first vaccine that prevents cancer.
You can help protect your children from hepatitis B by getting them vaccinated with three
doses of the hepatitis B vaccine.
Schedule-Newborn babies whose mothers are either infected with the hepatitis B virus or have
not been tested should get their first shot within 12 hours of birth, the second shot at one to
two months of age and the third shot at six months of age. Other babies can get their first shot
between birth and two months of age, the second at one to four months of age and the third at
six to 18 months of age.
Hepatitis b is produced by recombinant technology in yeast and adjuvanted with aluminium
salts and preserved with thiomersol.
It is available as single and multi dose vials and should be stored at 2 to 8 * c.
Dose- children and adolescents (aged < 18 years) is 0.5 ml and in those 18 years and older is 1
ml.
Site-It is given as intramuscular injection in the deltoid / anterolateral thigh.
Schedule- 0, 1 , 6 months.
Side effectsHepatitis B is a very safe vaccine. Some may have soreness at the injection site, a mild fever.
Irritability. More serious reactions are extremely rare. Like any vaccine or medicine hepatitis B
vaccine could theoretically trigger a serious reaction in someone who is allergic to one of its
components. But severe allergic reactions to childhood vaccines are very rare
Precautions
There are several reasons a doctor might want to delay giving child a hepatitis B vaccination or
not give it at all:
• A child who is known to have a severe allergy to baker's yeast, (the kind used for making
bread) should not get the hepatitis B vaccine.
• A child who had a severe allergic reaction after a dose of' hepatitis B vaccine should not get
another dose.
• A child who has a moderate or severe illness on the day hepatitis B (or any) vaccination is
scheduled should probably, delay the vaccination until he or she has recovered.
Babies born to infected mothers should also. Get hepatitis B· immune globulin (HBIG) within 12
hours of birth. Your child's doctor can give you, details. These babies should also be checked
when they are nine to 15 months old to make sure the vaccine worked and that they do not
have chronic hepatitis B virus infection.
DPwT
This vaccine protects against the three diseases, diptheria, pertusis, tetanus popularly known as
triple antigen, DPwT is composed of tetanus and diptheria toxoids as well as killed whole cell
pertusis bacilli adsorbed on insoluble aluminium salts.
Content is diptheria toxoid- 20 to 30 lf, tetanus toxid- 5 to 25 lf.
This vaccine should be stored at 2 to 8 degrees. Not to be frozen.
Dose- 0.5 ml intramuscularly.
Site - anterolateral aspect of thigh.
Schedule- 3 doses 1 month apart. 6. 10, 14 weeks of life.
2 boosters- 15- 18 months and 5 years.
Effectiveness of three doses exceeds 95 %.
Disease may occur in vaccinated individuals but in milder form.
Side effects- pain, swelling, redness at the local site. fever. Fussiness, anorexia, vomiting.
Absolute contraindications- history of anaphylaxis, encephalopathy within 7 days following
previous vaccination.
For such patients pertusis is to be avoided, other 2 components can be given.
Precautions- inconsolable cry more than 3 hours duration, hyperpyrexia (temp >40.5 degrres),
seizures with or without fever within 72 hours of vaccination, hypotonic hypo responsive
episode within 48 hours are considered precautions but not contraindications for further
doses. Catch up vaccination- schedule is 0, 1 and 6 months. 2nd booster is not required if last
dose is given beyond 4 years it is not recommended in children 7 years and beyond
DTaP
Serious adverse effects of pertusis component of whole cell vaccine led to development of
acellular pertusis vaccine.
Today it is available in combination forms as well.
It is to be stored at 2 to 8 degrees.
Schedule is 6, 10, 14 weeks followed by booster at 15 to 18 months and 5 years.
Dose- 0.5 ml intramuscularly .
Site- anterolateral aspect of thigh.
Adverse effects are reduced by 2/3 rd with acellular vaccine.
Absolute contraindications like anaphylaxis, encephalopathy are same for acellular vaccine.
This vaccine comes under category 3 vaccine- after one to one discussion with parents.
It is preferred in children with serious adverse effects due to whole cell component. And
children with neurological disorders.
Not to be used in children 7 years and older.
HIB VACCINE ( HAEMOPHILUS INFLUENZAE TYPE B )
HIB is a bacterial disease. It is spread through the air by coughing, sneezing or even breathing.
HIB bacteria enter a child's system through the nose or throat, and if they stay in the nose and
throat, the child will probably not become sick. But sometimes the bacteria spread into the
lungs or bloodstream. This is called invasive HIB disease, and it can cause serious
complications. In addition to meningitis, invasive HIB disease can lead to:
• Pneumonia
• Epiglottises (inflammation and swelling in the throat that can cause the child to choke)
• Arthritis, and other problems
Most invasive HIB disease occurs in children under five years old, and up to 60% in children
younger than one year. The disease is not common in older children or adults. Most HIB
disease today strikes infants who are not immunized. It probably takes about two to four days
from the time a child is exposed to HIB bacteria until symptoms appear. An infected
person can spread the disease to others for as long as the bacteria remain in the body.
Antibiotics can stop the spread within two to four days. HIB vaccine is an inactivated (killed)
vaccine. It is made from only a part of the HIB bacteria. Several different companies make the
HIB vaccine. Children should get either three or four doses, depending on which company's
vaccine your doctor is using. All children should get the vaccine at two and four months of age,
and a booster dose between 12 and 15 months. Some children should get an additional dose at
six months. Children who have passed their fifth birthday do not need a HIB vaccination. HIB
vaccine can be combined (given in the same shot) with the DTaP vaccine or with the hepatitis B
vaccine. Your child's doctor or nurse might offer the vaccines in these combination forms. They
work just as well, and are just as safe, as if the vaccines
were given separately.
Dose- 0.5 ml intramuscular.
Site- anterolateral aspect of thigh.
Schedule- 3 DOSES.
< 6 MONTHS- 3 DOSES.
6- 12 MONTHS- 2 DOSES.
12- 15 MONTHS- 1 DOSE.
BOOSTER AT 18 MONTHS.
FOR CHILDREN > 15 MONTHS SINGLE DOSE IS REQUIRED.
INTERVAL BETWEEN 2 DOSES SHOULD BE AT LEAST 4 WEEKS.
CATCH UP VACCINATION IS NOT RECOMMENDED FOR HEALTHY CHILDREN ABOVE 5 YEARS.
HOWEVER, VACCINE SHOULD BE ADMINISTERED TO ALL INDIVIDUALS WITH
FUNCTIONAL/ ANATOMIC HYPOSPLENIA IRRESPECTIVE OF AGE.
Side Effects-
HIB is a very safe vaccine. It cannot cause HIB disease or meningitis, and is not known to cause
any other serious reactions.
Some children may get some redness, swelling or warmth where the shot was given, or a fever
of over 101°F. These reactions usually begin within 24 hours after the shot is given and last up
to two or three days. They do not cause any permanent harm.
Like any vaccine or medicine, the HIB vaccine could theoretically trigger a serious reaction in
someone who is allergic to one of its components. But severe allergic reactions to childhood
vaccines are very rare.
PrecautionThere are several reasons a doctor might want to delay giving a child a HIB vaccination or not
give it at all:
• A child who has had a severe allergic reaction after a dose of the HIB vaccine should not get
another dose.
• A child who has a moderate or severe illness on the day a HIB (or any) vaccination is
scheduled should probably delay the vaccination until he or she has recovered.
• Children under four weeks of age should not get the HIB vaccine. This isn't because it is
unsafe, but because the vaccine might not protect as well when the first dose is given.
Combined Vaccines
Today, DTaP/DTwP are available as combined vaccines with IPV, Hib or Hep B.
Rotavirus
Rotavirus is a major cause of diarrhoea related morbidity and mortality in children worldwide.
Rotarix is a monovalent attenuated human rotavirus vaccine derived from the human rotavirus
strain 89 to 12 grown in vero cells and contains the G1P1 strain.
It is a live attenuated rotavirus vaccine.
It is indicated for active immunization of infants from age of 6 weeks for prevention of
gastroenteritis against rotavirus infection.
It is a lyophilised vaccine to be reconstituted with a liquid diluent before oral administration.
The course of vaccination consist of 2 doses which is 1 ml to be given oral.
Schedule-1 st dose should be administered from the age of 6 weeks.
There should be an interval of at least 4 weeks between 2 doses.
The vaccination should be completed by the age of 24 weeks.(6 months). Spitting or
regurgitation of vaccine is noted rarely, if required a single replacement
dose may be given at the same visit.
It is strongly recommended that infants who receive the 1 st dose should complete
the 2 nd dose regimen.
Rotarix is for oral use only. Under no circumstances should be injected.
There is no restriction for the intake of any food or liquid after the administration.
Contraindication- hypersensitivity with the 1st dose.
Precaution- vaccination should be postponed in a case of acute febrile illness,
in diarrhoea, in vomiting
Rotarix does not protect against the diarrhoea caused by the other pathogens.
It can be administered with other vaccines, including opv.
Side effects- irritability, loss of appetite, fever, fatigue.
Storage- the powder form should be stored at 2 to 8 degrees. If it is not used within
24 months after reconstitution it should be discarded.
Brand- rotarix- by gsk
PCV (Pneumococcal Polysaccharide Conjugated Vaccine)
It is pneumococcal polysaccharide conjugated vaccine.
prevenar is indicated for active immunization against infants and children from 6 weeks of age
through 9 years against invasive disease caused by streptococcal pneumonia which can cause
meningitis, sepsis, bacteraemia, pneumonia and otitis media.
the vaccine is to be stored at 2 to 8 degrees and available in prefilled syringe.
Dose - 0.5 ml intramuscularly.
Site- anterolateral aspect of thigh. Not to be given in gluteal area.
The first dose is given at the age of 2 months, as early as 1 and half month of age.
The dosing interval is 4 to 8 weeks. The fourth dose is to be given at 12 to 15 months of age.
For previously unvaccinated older children dose required are
1st dose at 7 to 11 months- 3 doses
at 12 to 23 months- 2 doses
at > 24 months to 9 years- 1 dose.
Contraindication- hypersensitivity of any components of vaccine.
Warning- prevenar will not protect against all the strains of bacteria which are not included in
the vaccine. In minor illness, low grade fever, vaccination should be postponed.
It is not indicated in pregnancy and lactation.
It can be co administered with other vaccines.
Efficiency of the vaccine is 96 to 98 % against the invasive diseases.
Side effects- erythema, induration, pain and swelling at the injection site, diarrhoea, vomiting,
fever, decreased appetite, irritability.
Brand - prevenar, manufactured by wyeth
Influenza Vaccine - INFLUVAC
It is an inactivated influenza virus surface antigen.
Indication- prophylaxis of influenza in those with increased risk of infection. Person >65 years,
adults and children with chronic pulmonary and cardiac disoredrs including asthma, in chronic
metabolic diseases like diabetes, in chronic renal disorders, immunodeficincy disorders, and
children on immunosupressive therapy, children who are on
long term aspirin therapy.
Schedule and dose- adults and children >36 months- 0.5 ml , children with <36 months- 0.25 ml
children who are not previously vaccinated should receive 2nd dose after 4 weeks of interval.
Vaccine is to be given intramuscularly or deep subcutaneously.
Contraindication- hypersensitivity, it should be postponed in acute febrile illness. Limited data
is available in administration of vaccine in pregnant women, can be given 2 nd trimester
onwards.
Side effects- haedache, swetting, myalgia, arthralgia, fever, malaise, fatigue.
Storage- at 2 to 8 degrees. Not to be frozen.
Manufactured by- solvay biologicals.
Measles
MMR vaccine is indicated for active immunisation against measles, mumps, and rubella.
it is available in the lyophilized form for reconstitution with diluents form which is sterile water.
it should be frozen for the long term storage. For the clinic use it can be stored at 2 to 8
degrees. The vaccine should be protected from light. After reconstitution it should be stored at
2 to 8 degrees and used within 4 to 6 hours.
Dose- 0.5 ml subcutaneously. It can also be given intramuscularly.
Two doses are recommended, one at 12 to 15 months and 2nd at 4 to 6 years or at any time
after 4 to 8 weeks of 1st dose.
it can be given with any other vaccine except BCG.
Site- anterolateral aspect of thigh.
This vaccine is highly immunogenic. It gives 98 % protection against measles, against mumps in
96 %, and against rubella in 99 %.
Contraindication- subjects with known hypersensitivity to any of the component of the vaccine,
patient with primary and secondary immunodeficiency, pregnancy.
Precautions- in acute illness vaccination should be postponed, patients with history of allergic
reactions.
Side effects- urti, rash, redness at the injection site, pain, swelling, fever.
This vaccine is category 2 vaccine.
Brand - priorix, by gsk.
HEPATITIS A VACCINE
Hepatitis A, like other types of hepatitis, is a disease that affects the liver.
Hepatitis A is caused by a virus. Children under six years old who get infected often don't show
any signs of illness. But for most older children,signs of hepatitis can come on quickly.
They include:
• fever
• loss of appetite and tiredness
• stomach pain
• vomiting
• dark urine.
• yellow skin or eyes( jaundice)
Hepatitis A can't be distinguished from other types of hepatitis except by blood testing.
Hepatitis A does not cause long term illness or liver damage like hepatitis B does. But every'
year about 1'00 people die from liver failure caused by severe hepatitis A. '.
The hepatitis A virus is found mainly in bowel movements and is spread through personal
contact or by eating contaminated food or drinking contaminated water. An infected person
can spread the virus to other people from about a week before symptoms appear through
about a week after.
People without symptoms can still spread the disease.
The hepatitis A vaccine is an inactivated (killed) vaccine. It can be given to children 12 months
of age. Two doses are needed, the second dose given six months after the first.
HAVRIX
It is an inactivated hepatitis a virus. A sterile suspension, containing inactivated hepatitis A
virus.
It is indicated for active immunization against infection caused by hepatitis A virus.
Schedule-Primary vaccination- a single dose 1 ml for adults. Children and adolescents from the
age of 1 year Havrix junior 0.5 ml is indicated.
Booster dose is indicated at any time between 6 months to 5 years.
Site-It is an intramuscular vaccination to be injected in deltoid in adults and anterolateral
aspect of thigh in younger children.
Seroconversion occurs in 99 % after 30 days of administration.
Contraindication- hypersensitivity to any component of vaccine.
Vaccination should be postponed in case of acute illness, in case of thrombocytopenia, bleeding
disorder.
Side effects- No major side effects.
Storage-It is to be stored at 2 to 8 degrees. do not freeze.
Brand- Manufactured by gsk.
VARICELLA VACCINE ( CHICKEN POX)
The most recognizable feature of chicken pox is an itchy rash allover the body. Children with
chicken pox can also be drowsy and have a fever.
Chicken pox can be spread very easily from person to person. It is spread through the air, by
coughing or sneezing, or even talking. It can also be spread by contact with fluid from the
blisters. It usually takes two to three weeks from the time a child is exposed to the chicken pox
virus until he or she becomes ill.
The disease is contagious from one or two days before the rash appears until all the blisters are
dried up,. which usually takes Four to five days. I
Chicken pox is usually a mild disease, uncomfortable but not dangerous. Still, serious problems
do occur. The blisters can become infected, and some children get encephalitis.
If a woman gets chicken pox just before or after giving birth, her baby can get very sick, and
about one in three of these children dies if not treated quickly.
A single dose of the varicella vaccine is recommended for children between 12 and 18 months
of age. It is usually given at the same time as the MMR injection. Children who miss this
injection can still get a single dose of the vaccine up to their 1st Birthday. Adolescents or adults
who have not gotten the vaccine by their 13th birthday will need two doses, four to eight
weeks apart. A child who has already had chicken pox disease does not need to get the vaccine.
There is some concern that a child who gets the chicken pox Vaccine can actually give chicken
pox to other, unprotected family members. This appears to happen extremely rarely, and Only
when the child who was vaccinated develops a rash. To be safe, anyone with a suppressed
immune system should consider avoiding contact with a child who develops a rash after getting
the chicken pox vaccination, just as they should avoid anyone with a case of chickenpox.
VARICELLA VACCINE
Varilrix is a lyophylised preparation of live attenuated oka strain of varicella zoster virus.
It is indicated for active immunization against varicella of healthy subjects and susceptible
healthy close contacts from age of 12 months onwards.
It is to be given subcutaneously.
Schedule and dose-From age 12 months to 12 years- 0.5 ml ,1 dose is required., from 13
years and above- 2 doses at least 6 weeks apart,but not less than 4 weeks interval.
Contraindications-primary or acquired immunodeficiency, malignancy,
clinically HIV infected patients, patients on immunosuppressive therapy, hypersensitivity to any
agents of vaccine, pregnancy, lactation.
Vaccination should be postponed in acute febrile illness.
Side effects- pain, redness, rash, swelling at the vaccination site seroconversion rates are > 98 %
storage- 2 to 8 degrees.
Brand- varilrix- gsk.
HPV VACCINE-( HUMAN PAPILLOMA VIRUS VACCINE)
Globally, cervical cancer is the second most common cancer in women.
To prevent this two vaccines are available, quadrivalent vaccine- gardasil and the other bivalent
vaccine- cervarix.
Both these vaccines are manufactured by recombinant DNA technology.

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