Mitochondrial Symposium Translational & Applied Bioenergetics Agenda Monday, March 2, 2015 1:00 pm – 1:10 pm Welcome and Opening Remarks Victor Darley-Usmar, PhD, University of Alabama at Birmingham Chairs: Victor Darley-Usmar and Anath Shalev 1.10 pm - 1:40 pm Control of the Nuclear Transcriptome by mtDNA Sequence. Insights from the Mitochondrial Nuclear Exchange Model Scott Ballinger, PhD, University of Alabama at Birmingham. 1:40 pm -2:10 pm Clinical Aspects of Mitochondrial Dysfunction in Neuropsychiatric Disorders Richard Frye, PhD, University of Arkansas Medical School 2:10 pm - 2:40 pm Mitochondrial Inner Membrane Dynamics in Stress and Cell Death Zheng Dong, PhD, Georgia Regents University 2:40 pm - 3:10 pm Platelet Bioenergetics in Cardiovascular Disease & Treatment Sruti Shiva, PhD, University of Pittsburgh 3:10 pm - 3:40 pm Coffee Break 3:40 pm - 4:00 pm Separating Mitochondrial Bioenergetics from Biogenesis: An uncharted role for PGC-1 coactivators Glenn Rowe, PhD, University of Alabama at Birmingham 4:00 pm - 4:20 pm Mitochondrial Measuring Bioenergetic Health in Human Populations Victor Darley-Usmar, PhD, University of Alabama at Birmingham 4:20 pm - 4:40 pm Quantitative Measurement of Bioenergetic Health in Human HIV Patients Sonya Heath, PhD, University of Alabama at Birmingham 4:40 pm - 5:00 pm Cytochrome c Oxidase as a Target for Cancer Therapy Corinne Criguer, PhD, University of Alabama at Birmingham 5:00 pm - 5:40 pm Keynote: Bioenergetics and Mitochondrial Dynamics in Health and Disease Orian Shirihai, PhD, Boston University & Ben Gurion University XF Users’ Group Meeting Preliminary Agenda Monday, March 2, 2015 12:00 pm - 7:00 pm Registration 5:00 pm - 5:40 pm Keynote: Bioenergetics and Mitochondrial Dynamics in Health and Disease Orian Shirihai, PhD, Boston University & Ben Gurion University 6:00 pm - 8:00 pm Welcome Reception __________________________________________________________ Tuesday, March 3, 2015 7:00 am - 9:00 am Breakfast 9:00 am - 9:15 am Welcome Remarks 9:15 am - 10:00 am Plenary: Metabolic Regulation of Cardiac Progenitor Cells Brad Hill, PhD, University of Louisville 10:00 am - 10:45 am Presentation: Fuels: The Next Wave of XF Bioenergetic Assays David Ferrick, PhD, CSO, Seahorse 10:45 am - 11:15 am Coffee Break 11:15 am - 11:40 am XF User Presentation 11:40 am - 12:05 pm XF User Presentation 12:05 pm - 1:15 pm Lunch 1:15 pm - 1:55 pm Workshops - 3 Parallel 1:55 pm - 2:35 pm Workshops - 3 Parallel 2:35 pm - 3:00 pm Coffee Break 3:00 pm - 3:25 pm XF User Presentation 3:25 pm - 3:50 pm XF User Presentation 3:50 pm - 4:30 pm New XF Products Update 6:00 pm - 7:00 pm Cocktails 7:00 pm - 9:00 pm Dinner __________________________________________________________ Workshop Options:  FAO & Substrate Assays  Measuring Mitochondrial Respiratory Complexes in Cells Using XF PMP  Normalization  Resources for XF Assays  XF Stress Test Refresher  3D Biology: New Spheroid Assay Tools  XFp Extracellular Flux Analyzer  Vessel Assays  Hypoxia  Substrate Tool Box  XF Assays in Core Labs Wednesday, March 4, 2015 7:00 am - 9:00 am Breakfast 9:00 am - 9:15 am Welcome Remarks 9:15 am - 10:00 am Plenary: Mitochondrial Protein Thiol Networks: A New Target for Modulating Cancer Metabolism Aimee Landar PhD, University of Alabama at Birmingham 10:00 am - 10:25 am User Presentation 10:25 am - 10:50 am User Presentation 10:50 am - 11:15 am Break 11:15 am - 12:00 pm Panel Discussion 12:05 pm - 1:15 pm Lunch 1:15 pm - 1:45 pm Workshops - 3 Parallel 1:45 pm - 2:15 pm Remarks 2:15 pm - 2:30 pm Closing Remarks