primary vascular tumours of bone

Cover Page
The handle http://hdl.handle.net/1887/32718 holds various files of this Leiden University
dissertation.
Author: Verbeke, Sofie Lieve Jozef
Title: Primary vascular tumours of bone: towards a new classification based on pathology
and genetics
Issue Date: 2015-04-14
PRIMARY VASCULAR TUMOURS OF BONE:
TOWARDS A NEW CLASSIFICATION BASED
ON PATHOLOGY AND GENETICS
Primary vascular tumours of bone: towards a new classification based on pathology and
genetics.
Thesis, University of Leiden
ISBN 978-94-6108-922-9
Printed by: Gildeprint – Enschede
Cover: George Minne – Fountain with Kneeling Youghts – MSK Gent - © ‘Image: Lukas Art in Flanders VZW
Copyright ©2015, Sofie Verbeke, the Netherlands
No part of this thesis may be reproduced, stored or transmitted without prior permission of
the author.
PRIMARY VASCULAR TUMOURS OF BONE:
TOWARDS A NEW CLASSIFICATION BASED
ON PATHOLOGY AND GENETICS
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van de Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties
te verdedigen op dinsdag 14 april 2015
klokke 13.45 uur
door
Sofie Lieve Jozef Verbeke
geboren te Gent (België)
in 1977
Promotiecommissie
Promotor:
Leden:
Prof. Dr. J.V.M.G. Bovée
Prof. Dr. P.C.W. Hogendoorn
Prof. Dr. R. Sciot (KU Leuven)
Prof. Dr. A.J. H. Suurmeijer (Rijksuniversiteit Groningen)
Dr. K. Szuhai
Wijsheid vindt men in de boeken
Wijs zijn zal men verder zoeken
Guido Gezelle (1830 - 1899)
Aan Ricky, Lysander en Aeneas
Contents
Chapter 1
General introduction
Chapter 2
Primary vascular tumors of bone: a spectrum of entities?
Int J Clin Exp Pathol 2011. 4(6): 541-51.
25
Chapter 3
Distinct histological features characterize angiosarcoma of bone.
Histopathology 2011. 58(2): 254-64.
41
Chapter 4
Active TGF-beta signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.
Mod Pathol 2013. 26(9): 1211-21.
59
Chapter 5
Opening the archives for state of the art tumor genetic research: sample processing for array-CGH using decalcified, formalin-fixed,
paraffin-embedded tissue derived DNA samples.
BMC Res Notes 2011. 4: 4-1.
77
Chapter 6
Array CGH analysis identifies two distinct subgroups of primary angiosarcoma of bone.
Genes Chromosomes Cancer 2015.54(2): 71-81.
95
Chapter 7
A reappraisal of hemangiopericytoma of bone; analysis of cases reclassified as synovial sarcoma and solitary fibrous tumor of bone.
Am J Sug Pathol 2010. 34(6): 777-83.
113
Chapter 8
Summary and future perspectives
127
Chapter 9
Nederlandse samenvatting
135
Chapter 10 List of publications
Curriculum vitae
Nawoord
9
147
149
151

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