Title Pages_Contents - Universiteit Leiden

Cover Page
The handle http://hdl.handle.net/1887/32551 holds various files of this Leiden University
dissertation.
Author: Krol, Charlotte Georgette
Title: Pitfalls in the diagnosis and management of skeletal complications of liver
transplantation
Issue Date: 2015-03-19
Pitfalls in the diagnosis and management of
skeletal complications of liver transplantation
Charlotte Krol
Cover graphics based on a painting by Peter J. Krol
Layout and printed by: Optima Grafische Communicatie, Rotterdam, The Netherlands
ISBN: 978-94-6169-630-4
Financial support: Printing of this thesis was financially supported by the Catharina
Hospital in Eindhoven and the Dutch Society for Calcium and Bone Metabolism.
© Charlotte G. Krol, 2015. All rights reserved. No part of this publication may be
reproduced, stored in a retrieval system or transmitted in any form or by means, without
prior written permission of the author.
Pitfalls in the diagnosis and management of
skeletal complications of liver transplantation
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden
op gezag van
Rector Magnificus prof. mr. C.J.J.M. Stolker
volgens besluit van het College voor Promoties
te verdedigen op donderdag 19 maart 2015
klokke 15:00
door
Charlotte Georgette Krol
geboren te Rijswijk
in 1983
Promotiecommissie
Promotor
Prof. dr. B. van Hoek
Overige leden
Prof. dr. P. Lips
Co-promotor
Mw. dr. N.A.T. Hamdy
Prof. dr. S.E. Papapoulos
Vrije Universiteit Amsterdam
Mw. dr. M.M.J. GuichelaarMedisch Spectrum Twente Enschede en
Mayo Clinic, Rochester MN, USA
time is short and work is long
[…] you are forced to omit so many needful studies,
and pass by so many needy souls, for want of time
yet if you look not well about you,
and will not bear some censure and offence
you shall lose even the rest of the time
which now you do improve
Richard Baxter (1615-1691)
Contents
Chapter 1
General Introduction
Chapter 2
No association between BMD and prevalent vertebral
fractures in liver transplant recipients at time of screening
9
41
before transplantation
Chapter 3
Longitudinal changes in BMD and fracture risk in
orthotopic liver transplant recipients not using bone
57
modifying treatment
Chapter 4
Pitfalls in the interpretation of bone turnover markers in
75
Chapter 5
Bisphosphonates in the prevention of bone loss after liver
97
liver transplantation
transplantation: a comprehensive review of the literature
and a case series from the Leiden Liver Transplantation
Cohort Study
Chapter 6
Summary and Conclusions
119
Nederlandstalige Samenvatting
125
List of Abbreviations
129
Dankwoord
131
List of publications
129
Curriculum Vitae
135

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