Systemic lupus erythematosus

Systemic lupus erythematosus:
a behavioural medicine perspective
Gabriëlle Mathilde Nicoline Daleboudt
Daleboudt, G.M.N.
Systemic lupus erythematosus: a behavioural medicine perspective
ISBN: 978-90-5335-867-2
Printed by: Ridderprint, Ridderkerk
Cover design: Nikki Vermeulen and Gabriëlle Daleboudt
The printing of this thesis was financially supported by: GlaxoSmithKline BV, Dutch
Arthritis Foundation, Lupus Nederland, and NVLE Fonds.
Systemic lupus erythematosus:
a behavioural medicine perspective
Proefschrift
ter verkrijging van
de graad Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties
te verdedigen op donderdag 25 september 2014
klokke 10.00 uur
door
Gabriëlle Mathilde Nicoline Daleboudt
geboren te Delft in 1983
PROMOTIECOMMISSIE
Promotores:
Prof. dr. A.A. Kaptein
Co-promotor:
Dr. S. P. Berger
Overige leden:
Prof. dr. J. Dekker
Prof. dr. J.W. de Fijter
Prof. dr. T.W.J. Huizinga
Prof. dr. M.E. Numans
Prof. dr. J.B. Prins
Prof. dr. J.A. Weinman
Voor Arjen
CONTENTS
Chapter 1
General introduction
Chapter 2
The clinical relevance of a repeat biopsy in lupus
nephritis flares
31
Concentration controlled treatment of lupus nephritis
with mycophenolate mofetil
49
Health-related quality of life in patients with systemic
lupus erythematosus and proliferative lupus nephritis
67
The impact of illness perceptions on sexual
functioning in patients with systemic lupus
erythematosus
85
Chapter 3
Chapter 4
Chapter 5
Chapter 6
9
Illness perceptions in patients with systemic lupus
erythematosus and proliferative lupus nephritis
103
Intentional and unintentional treatment nonadherence in patients with systemic lupus
erythematosus
125
Chapter 8
General discussion
147
Chapter 9
Summary
161
Chapter 10
Nederlandse samenvatting
167
Chapter 7
Supplement 1 Dankwoord
Supplement 2 Curriculum vitae
Supplement 3 List of publications
175
181
185