Day 1 – October 29 09.15 – 09.30 Opening 09.30 – 10.00

Day 1 – October 29 09.15 – 09.30 Opening 09.30 – 10.00 Stefan Braam / Pluriomics B.V. Pluricyte‐cardiomyocytes: benefits and characteristics of improving the maturity of stem‐cell derived cardiomyocytes with a fully‐defined culture medium 10.00 – 10.30 Sara Russo Kraus (Group De Haan) / Universitair Medisch Centrum Groningen Transcriptome and epigenetic profiling of young and aged hematopoietic stem cells 10.30 – 11.00 Break 11.00 – 11.20 Eric van der Veer (Group Zonneveld) / Leids Universitair Medisch Centrum Genome‐wide assessment of post‐transcriptional events orchestrated by Quaking that determine monocyte fate 11.20 – 11.40 Merhnaz Ghazvini (Group Gribnau) / Erasmus MC Induced pluripotent stem cell core facility of Erasmus MC 11.40 – 12.00 Marcel Boerman / Bender Analytical Holding B.V. Development of a poly(2‐oxazoline) based haemostatic agent 12.00 – 12.20 Koen Braat (Group Coffer) / Universitair Medisch Centrum Utrecht Patient specific induced pluripotent stem cells to study blood related disorders 12.20 – 14.20 Break and poster session 14.20 – 14.50 Martti Maimets (Group Coppes) / Universitair Medisch Centrum Groningen Canonical Wnt/‐catenin pathway in salivary gland irradiation and regeneration 14.50 – 15.20 Calinda Dingenouts (Group Goumans) / Leids Universitair Medisch Centrum DPP4 inhibition increases MNC homing but deteriorates cardiac recovery in Eng+/‐ mice 15.20 – 15.40 Andrea Brum (Group Van Leeuwen) / Erasmus MC Connectivity map‐based discovery of parbendazole as a novel osteogenic compound 15.40 – 16.10 Break 16.10 – 16.30 Ed Eringa (Group Van Hinsbergh) / VU medisch centrum Contrast‐enhanced ultrasonography for unraveling molecular control of organ perfusion 16.30 – 16.50 Renze Heidstra (Group Scheres) / Wageningen Universiteit Patterning and maintenance of the Arabidopsis root stem cell niche 16.50 – 17.10 Rutger Gjaltema (Group Bank) / Universitair Medisch Centrum Groningen Transcriptional silencing of PLOD2 induced by targeted epigenetic editing in pro‐
fibrotic fibroblasts Dag 2 – October 30 09.00 – 09.30 Salvatore Simmini (Group Deschamps) / Hubrecht Instituut Cell‐autonomous transformation of Lgr5‐positive intestinal stem cells into gastric stem cells upon loss of transcription factor Cdx2 09.30 – 10.00 Antonio Gonzalves Castro (Group John Jansen) / Radboud University Nijmegen Medical Centre Development of porous PLLA micro‐cylinders for tissue engineering applications 10.00 – 10.20 Olivier de Jong (Group Verhaar) / Universitair Medisch Centrum Utrecht A regulatory role for lysyl oxidase like 2 in endothelial to mesenchymal transition 10.20 – 10.50 Break 10.50 – 11.10 Emma de Pater (Group Dzierzak) / Erasmus MC An unexpected requirement for Gpr56 revealed by whole transcriptome analysis of endothelial‐to‐hematopoietic stem cell transition 11.10 – 11.30 Sofia Karkampouna (Group Ten Dijke) / Leids Universitair Medisch Centrum Inhibition of TGF type I receptor activity facilitates liver regeneration upon acute CCl4– intoxication in mice 11.30 – 11.50 Dorota Kurek (Group Ten Berge) / Erasmus MC Endogenous Wnt signals mediate spontaneous and BMP‐ induced differentiation of epiblast stem cells and human ES cells 11.50 – 12.10 Roberto Narcisi (Group Van Osch) / Erasmus MC WNT3A modulation in vitro leads to stable cartilage formation in vivo 12.10 – 14.10 Break and poster session 14.10 – 14.40 Santiago Gisler (Group Van Lohuizen) / Nederlands Kanker Instituut Exploring novel BMI1 interactions: A loss‐of‐function genetic screen on haploid cells 14.40 – 15.10 Catalina Gomez Puerto (Group Coffer) / Universitair Medisch Centrum Utrecht ATG5 and ATG7 fulfill essential and non‐redundant roles in human hematopoietic stem/progenitor cells 15.10 – 15.30 Kristel Boere (Group Hennink) / Universiteit Utrecht Hydrogels formed by tandem thermogelation and native chemical ligation 15.30 – 16.00 Break 16.00 – 16.20 Ester Weijers (Group Koolwijk) / VU medisch centrum In vitro 3D microvascular networks in biomatrices, an innovative tool to study angiogenesis for regenerative medicine 16.20 – 16.40 Cathelijne van de Berg (Group Mummery) / Leids Universitair Medisch Centrum Comparison of human induced pluripotent stem cell‐ and embryonic stem cell‐derived cardiomyocytes 16.40 – 17.00 Sabine Welten (Quax) / Leids Universitair Medisch Centrum Inhibition of individual 14q32 microRNAs drastically increases neovascularization and blood flow recovery after ischemia