Entry
Reverse transcription
HIV dsDNA
HIV ssRNA
genome
Integration
Host genomic
DNA
Figure 1. HIV-1 Integrase: A New Drug Target
For entry HIV binds to receptors (CD4; blue and CCR5 or
CXCR4; green) and releases viral single-stranded RNA genome
that is subsequently reverse transcribed to double-stranded DNA.
Elvitegravir inhibits integrase that mediates an essential step,
integration of HIV dsDNA into host genomic DNA.

DNA sample preparation for epigenetic qPCR

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