The Biological Pesticide Market Dr. Matthew Phillips, Phillips McDougall AgriService The last few years has seen a significant level of investment from conventional agrochemical companies in the biological pesticide sector. This investment has encompassed new product development and expenditure on new facilities, as well as a number of significant product and company acquisitions. Acquisitions Involving Biological Pesticides (2010-present) Company Year Plant Health Care 2010 Intellectual property portfolio of Myconate from Bayer CropScience MAI 2010 Plant growth regulator Talent, based on the active ingredient Carvone, from Formuchem Becker Underwood 2010 Biological Control Products (BCP), a producer of biological crop protection products based in South Africa Bayer 2010 Biofungicide Shemer from Israeli company AgroGreen Bayer 2010 A Varroa mite (Varroa destructor) control product from Exosect Tessenderlo Kerley 2011 Purfresh Inc’s crop protection sun screen business and product line Syngenta 2012 US-based company Pasteuria Bioscience Novozymes 2012 US-based biological pest control company Natural Industries MGK 2012 Assets related to the biological insecticide Veratran-D Koppert 2012 Brazilian bioproducts company Itaforte Bioproducts CBC Group 2012 Italian biopesticide company Intrachem Bio Italia Bayer 2012 US-based biological crop protection company AgraQuest BASF 2012 US-based biological products company Becker Underwood Andermatt Biocontrol 2012 24.9% stake in the Germany biopesticide company Abitep De Sangosse 2013 Equity stake in the UK-based company Alpha Biopesticides Bayer 2013 German biological crop protection company Prophyta Amvac 2013 29.46% ownership position in the US-based biological insecticide company TyraTech Novozymes 2013 TJ Technologies FMC 2013 Acquired CAEB, a division of the North-Carolina based company RTI International AGROLOOK Acquisition 1 JAN-MARCH 2014 For the purposes of this review the term biological pesticide is taken to include biologically based herbicides, insecticides, fungicides and other products, including organisms, with actions that are used in the crop protection sector. Based on this definition there are four main types of products considered to be in the sector: significant product category commercially in 2012 was natural products, which accounted for $1,148 m., equivalent to 63.3% of the overall biological market. Thereafter the most significant product type was microbial-based biopesticides, which accounted for a further $479 m. Quantification of the Current Biological Product Market by Product Type A. Macrobials Macrobial biological products that are used in crop protection comprise living organisms that are either predatory or parasitic in their action against pests, usually insects. Product type Sales (US $m) % of total Macrobials 138 7.6 Microbials 479 26.4 Products in this category include parasitic insects such as wasps that lay their eggs within an insect pest; predatory insects such as ladybugs, lacewings and insect larvae that are predators of insect pests; and nematodes that act as natural parasites on insect larvae. Semiochemicals 48 2.7 63.3 Grand Total 100 1813 In contrast to natural products and microbials, biological pesticides based on macrobials and semiochemicals are commercially less significant, contributing a value of $ 138 m. and $ 48 m. respectively. B. Microbials Microbial pesticides comprise microorganisms, usually a bacterium, virus, fungus or protozoan, applied directly to plants that have activity against a particular crop pest. Commercially the most important microbial pesticides are varieties of Bacillus thuringiensis: these are active in the control of several important lepidopteran larvae. The following table outlines the sales of the leading six biological pesticide products. Four of the leading biological pesticide products are classified as natural products, with the leading product being abamectin with sales of $ 360 m. in 2012, followed by spinosad with sales of $ 260 m. In total the six leading products accounted for a sales total of $ 1175 m., equivalent to 64.8% of the biological pesticides market. C. Semiochemicals Semiochemicals used in crop protection comprise pheromones that act by modifying insect behaviour. These products are used to interfere with insect mating or act as attractants for insect traps. Sales of Leading Biological Pesticides in 2012 D. Natural products Products within this category include fermentationbased products with activity as crop protection agents, as well as naturally derived products that have activity against pests and diseases. Based on our analysis of the products, companies and markets that make up the sector, the overall value of the market for biological pesticides as defined above was estimated to have been $1813 m. in 2012. Within this value the most AGROLOOK Natural Products 1148 2 Product type Active Ingredient 2012 Sales (US $m) Natural Products Abamectin 360 Natural Products Spinosad 260 Natural Products Emamectin benzoate 180 Natural Products Spinetoram 165 Microbials Bacillus thuringiensis 160 Microbials Bacillus subtilis 50 JAN-MARCH 2014 Whilst the major companies have during periods in the past made some entrances into the biological products sector, it was not until the expansion of abamectin for use as a nematicidal seed treatment to great success that a major interest in this sector started. Abamectin as a seed treatment was soon followed by Bacillus firmis, again as a nematicidal seed treatment, with a number of recent acquisitions also driven by activity in this particular sector. All of the products in the above list have insecticidal activity, except for Bacillus subtilis which is used for the control of bacterial and fungal diseases on a range of crops, but particularly oilseed rape, vine and potato. Quantification of the Current Biological Product market by Region For the biological pesticide sector as a whole, the most important crop outlet is believed to be the conglomerate fruit and vegetable market, in part reflecting the use of these products in relatively enclosed environments. Thereafter the most important individual crop sector is estimated to have been cotton, followed by rice, with maize gaining in importance. The biological products with activity as nematicidal seed treatments have the greatest impact in maize and cotton. Although the leading regional market for biological pesticides is estimated to have been Asia, the leading country market is the USA, with an estimated value of $ 438 m. in 2012, followed by China ($ 233 m.), Japan ($ 203 m.), Brazil ($ 137 m.) and India ($ 96 m.). % of Total NAFTA 503 27.8 Latin America 207 11.4 Europe 252 13.9 Asia 782 43.1 Middle East & Africa 69 3.8 Grand Total 1813 100.0 A key concern regarding biological products has always been reproducibility of activity in open field situations, as a result at present the major markets are on fruit and vegetables, particularly those grown in glasshouses in controlled environments. However, this situation is now changing, with increasing usage of biological seed treatments, also a controlled environment when products are encapsulated around the seed. This is expanding the usage of biologicals in row crop sectors. A noticeable link between a number of the recent mergers and acquisitions has been product opportunities such as seed treatments, particularly with nematicidal activity. Fruit and vegetables 56.2% Maize 3.6% Rice 6.8% Cotton 9.0% Whilst the market for biological products is improving from a relatively low base, it is unlikely that the sector will achieve high growth rates until reproducibility of action in the field can be proven. Interestingly, Europe has a relatively low share of the sector at present, although this is likely to change in the near future, with a higher proportion From a regional perspective the leading market for biological pesticides is Asia, which accounted for a total value of $782 m., equivalent to 43.1% of the total market, followed by North America with a 27.8% share. AGROLOOK Sales (US $m) Overview and Outlook Sales of Biological Pesticides Split by Leading Crop Sector – 2012 Other crops 24.4% Region 3 JAN-MARCH 2014 of the products awaiting Annex 1 approval now biologicals. Also, 1107/2009, the current EU agrochemical product registration legislation, calls for ‘comparative assessment of products and replacement with safer alternatives’; a safer alternative may well be a biological solution. Under the most recent amendment to the common agricultural policy, which was agreed in mid-2013, for farmers to sustain direct subsidy payments they are obliged to embrace integrated pest AGROLOOK management, which again should provide a market opportunity for biological products. A key factor is likely to be greater R&D investment in the area now that many of the major agrochemical companies have an interest in the sector; this coupled with the market opportunities listed above suggests that the biologicals sector may perform ahead of the crop protection sector as a whole, which is expected to grow by 2.3% p.a. in volume terms through to 2017. 4 JAN-MARCH 2014
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