Zinc-Net conference Program 3rd of November 2014 Venue: St Giles Church Fore St, Barbican, London EC2Y 8DA 10.00-10.45 Registration with tea/coffee biscuits 10.45-11.00 Welcome and announcements by Nickola Lowe, Lothar Rink and Imre Lengyel 11.00-11.45 Zinc sensing chaired by Mike Watkinson 11.00-11.15 Jess Pancholi, Queen Mary University of London, UK Location, location, location: A one-pot route to biologically targeted zinc sensors 11.15-11.30 Mat Todd, University of Sydney, Australia Click-cyclam Ligands in Zn(II) Sensing and Biology 11.30-11.45 Maarten Merkx, Technische Universiteit Eindhoven, Netherlands Genetically-encoded optical tools to understand zinc homeostasis and signalling 11.45-12.30 Keynote presentation: Richard Thompson, University of Maryland, USA Present and future of zinc sensing: Detection without instrumentation 12.30-14.00 Lunch and Posters in the Church 14.00-15.30 Determining Zinc distribution and concentration with non-fluorescent methods chaired by Imre Lengyel 14.00-14.15 Agnete Larsen, Aarhus University, Denmark Autometallography 14.15-14.30 Helen Reid, Loughborough University, UK Laser ablation-inductively coupled plasma mass spectroscopy 14.30-14.45 Sarah Fearn, Imperial College London Secondary ion mass spectrometry and other surface techniques 14.45-15.00 Antje Biesemeier, University of Tubingen, Germany Analytical Electron Microscopy 15.00-15.15 Pete Kille, University of Cardiff, UK X-ray fluorescence and other methods 15.15-15.30 Arie Moran, Israel ZnT-1 the masters of two servants, zinc transport and calcium channel regulation 15.30-16.00 Posters with Tea/coffee 16.00-17.30 Selected oral presentations chaired by Elisa Bellomo 16.00-16.15 Duncan Wilson Zinc scavenging by the human pathogenic fungus Candida albicans 16.15-16.30 Peter Faller Zinc-binding to amyloid-beta: structure, aggregation and cross talk with metalloproteins 16.30-16.45 Ogo Ogo ZNF658 mediates zinc homeostasis through the zinc transcriptional regulatory element 16.45-17.00 Marco Malavolta Accelerated Senescence of Human Coronary Endothelial Cells by a Moderately Excessive Zinc Environment 17.00-17.15 Jaap Keijer Exposure to mild hypoxia does not induce inflammation in white adipose tissue of obese mice, but affects expression of CCDC3 and Zinc-finger containing transcriptional repressors 17.15-17.30 Michal Hershfinkel Zn2+ release under physiological conditions: Seeing is believing 17.30-18.00 Closing remarks and Zinc-Net issues: Nicola Lowe and Imre Lengyel 18.00-19.30 Posters and Wine, Cheese and Nibbles in the Church This meeting is funded by the FA COST Action TD1304 “The Network for the Biology of Zinc”