Mini-Report Skin Rejuvenation: Continually Advancing Technology i. Methodology Skin rejuvenation data was compiled from a wide variety of public and proprietary sources. Information was cross-checked against other data, using Medical Insight’s proprietary forecasting models, and synthesized into both qualitative and quantitative analyses and projections. Public sources that were utilized include: - articles in trade publications, medical journals and regulatory documents; - articles in consumer magazines and newspapers; - company news releases, website information, patent documents, regulatory data, marketing materials and financial filings; - information from trade associations Proprietary sources that were utilized include: - Medical Insight’s extensive database of industry and product information; - Medical Insight’s physician survey data; - industry analyst reports; - exclusive interviews with, and feedback from, company executives, researchers, sales representatives, physicians, patients, consultants and other industry experts miinews.com Medical Insight, Inc. 2 Mini-Report Skin Rejuvenation: Continually Advancing Technology ii. New in October 2013 This mini report represents the sixth edition of Medical Insight, Inc.’s Skin Rejuvenation report. Like its predecessor, which was published in April 2013, this report contains the latest industry news and updated market forecasts, which take into account recent technology, product, company, regulatory and other developments, as well as an in-depth analysis of the competitive positions of key players selling to both core and non-core aesthetic practices. In addition to updated qualitative and quantitative product, global and regional manufacturer and market information, this report also includes: - Quotes from industry thought leaders and top executives; - videos of selected devices; - expanded tables, graphs and images. miinews.com Medical Insight, Inc. 3 Mini-Report M.I.I Skin Rejuvenation: Continually Advancing Technology Disclaimer Information in this study has been obtained by Medical Insight, Inc. from sources believed to be reliable. While Medical Insight believes the data provided herein to be accurate, no expressed or implied guarantees regarding accuracy or adequacy are made. Product and corporate data can change very quickly and without notice and Medical Insight continually updates its research products. Because of this, certain figures in Medical Insight reports may differ from corresponding figures in earlier reports, even if those reports were issued relatively recently. Furthermore, current economic conditions are contributing to a highly volatile market, in which actual results often diverge significantly from estimates developed by manufacturers, analysts and others, resulting in a revision of projections. Therefore, while Medical Insight will provide an explanation of figures in any of its reports, only the most recent reports contain Medical Insight’s latest estimates. This study is not intended as a substitute for proper due diligence. Although an attempt has been made to provide thorough coverage of the subject matter of this report, no guarantees regarding completeness or thoroughness are made. Medical Insight is not responsible for any errors, omissions, or results obtained from use of information provided herein. Any use which a reader makes of this report or any reliance on or decisions to be made based on it are the sole responsibility of such reader. Medical Insight accepts no responsibility for damages, if any, suffered by any reader as a result of decisions or actions taken based on this study. Medical Insight, Inc. reserves all rights to this copyrighted document. This study is protected by U.S. Copyright Law; Copyright 2013 Medical Insight, Inc. Unauthorized reproduction is strictly forbidden by law. This report may not be reproduced in part or in whole without written consent of a duly authorized officer of Medical Insight. Multiple copies of this report can be obtained at a nominal cost by contacting the publisher. Medical Insight, Inc. 130 Vantis, Suite 240 Aliso Viejo, CA 92656 USA +1 (949) 830-5409 telephone +1 (949) 830-8944 facsimile Email: [email protected] miinews.com Medical Insight, Inc. 4 Mini-Report M.I.I Skin Rejuvenation: Continually Advancing Technology Professional Biography Michael Moretti President Medical Insight, Inc. Michael Moretti has served as a medical industry analyst and strategic advisor for more than 20 years. As an industry consultant, Mr. Moretti specializes in strategic business development projects and high-growth, emerging market segments. He provides custom reports and confidential market studies for a variety of clients, including global medical and pharmaceutical companies. In 1993, Mr. Moretti founded Medical Insight, Inc., the leader in focused aesthetic market research offering comprehensive data on procedure volume and growth, revenue forecasts and new product introductions. Under Mr. Moretti’s leadership, Medical Insight publishes global market studies and forecasts for major industry sectors such as facial injectables, cosmeceuticals, body shaping procedures, skin rejuvenation technologies and home-use aesthetic products. Medical Insight also sponsors executive business forums to address scientific developments and market trends for the investment community. Mr. Moretti is the founder of Aesthetic TV®, the first and only one-stop online resource for current, reliable information about cosmetic and anti-aging treatments. Aesthetic TV offers expert advice for consumers via interviews with the top physicians in the field, and unprecedented access to the latest beauty-enhancing procedures and products created specifically to help people look and feel their absolute best. Mr. Moretti is also founder and publisher of THE Aesthetic Guide® – a digital and print publication from Medical Insight featuring in-depth reports on new products, procedures and trends, reaching over 50,000 physicians, industry executives and investment analyst subscribers globally. Special editions of THE Aesthetic Guide address the European market and the Asian markets. In 2007, Mr. Moretti debuted THE Aesthetic Show™, the first multidisciplinary annual business to business trade show that brings thousands of the highest profile physicians and medical professionals together in Las Vegas to learn about the newest aesthetic procedures, products and technologies in a dynamic, interactive, educational format. For more information please visit: www.miinews.com. Contact Information: Michael Moretti Medical Insight, Inc. 130 Vantis, Suite 240 Aliso Viejo, CA 92656 USA +1 (949) 830-5409 telephone +1 (949) 830-8944 facsimile Email: [email protected] Or visit the Medical Insight website at: www.miinews.com miinews.com Medical Insight, Inc. 5 Mini-Report M.I.I Skin Rejuvenation: Continually Advancing Technology Table of Contents Disclaimer 4 Biography 5 Table of Contents 6 Table of Exhibits 8 1.0 Executive Summary 9 2.0 Background 10 3.0 Market Analysis 12 4.0 Market Forecast 18 5.0 4.1 Equipment 19 4.2 Disposables 24 4.3 Procedure Volume 26 Manufacturer Profiles 27 5.1 Alma Lasers 27 5.2 Beijing Sincoheren 29 5.3 Benev 30 5.4 Cutera 31 5.5 Cynosure 31 5.6 DEKA 36 5.7 Dinona 37 5.8 Ellipse 37 5.9 Ellman International 38 5.10 Energist 39 5.11 Ilooda Co., Ltd. 40 5.12 InMode / Invasix 41 5.13 Jeisys 41 5.14 Laser.com 42 5.15 LASERING S.r.l. 42 5.16 Lumenis 43 5.17 Lumiere 45 miinews.com Medical Insight, Inc. 6 Mini-Report Skin Rejuvenation: Continually Advancing Technology 5.18 Lutronic 46 5.19 MedixSysteme 47 5.20 Miracle International Co., Ltd. 47 5.21 Myoscience 48 5.22 Pantec Biosolutions 49 5.23 Perfaction 49 5.24 Quanta System 50 5.25 RioBlush 50 5.26 Sciton 51 5.27 ShenZhen GSD Tech Co.Ltd. 53 5.28 Solta Medical 53 5.29 Syneron 56 5.30 TavTech 59 5.31 Viora 60 miinews.com Medical Insight, Inc. 7 Mini-Report M.I.I. Skin Rejuvenation: Continually Advancing Technology Table Of Exhibits Figure 1: Microneedle Skin Rejuvenation Table 1: Top Skin Rejuvenation Devices Table 2: Fractional Skin Rejuvenation Devices Table 3: Installed Base of Skin Rejuvenation Devices Figure 2: Market Shares of Top Skin Rejuvenation Players Table 4: Sales of Skin Rejuvenation Devices, 2012 – 2017 Figure 3: Skin Rejuvenation Device Market by Company, 2012 – 2017 Table 5: Worldwide Projected Dollar Sales for Skin Rejuvenation Devices, by Region, 2012 – 2017 Table 6: Sales of Skin Rejuvenation Disposables, 2012 – 2017 Figure 4: Skin Rejuvenation Disposables Market by Company, 2012 – 2017 Table 7: Procedure Volume for Skin Rejuvenation, 2012 – 2017 miinews.com Medical Insight, Inc. 11 12 16 20 21 22 23 24 25 25 26 8 Mini-Report Skin Rejuvenation: Continually Advancing Technology Section 1 Executive Summary Demand for a low downtime procedure that can quickly improve the skin’s appearance remains high. An improving U.S. economy in which unemployment has recently declined to 7.3%, a record high stock market and increased consumer confidence is also supporting consumer spending. Over the next five years, skin rejuvenation platform revenues will expand by 8.1% per year, on average, from $324.4 million in 2012 to $478.5 million in 2017. This is lower than the CAGR of 9.0% predicted in Medical Insight’s prior skin rejuvenation report, released in April 2013, and reflects flat overall sales of several leading players. North America represents the largest regional market for skin rejuvenation devices. It will remain the largest market through 2017, with growth of 7.1% per year as the economy recovers and aesthetic practitioners acquire new devices to keep up with current technology. This compares with annual growth of 12.9% in Asia, 11.8% in Latin America and just 5.8% in Europe. As the installed base of skin rejuvenation platforms increases, sales of disposables, such as handpieces, will grow from $33.6 million in 2012 to an estimated $53.2 million in 2017. Key technology trends include combining topicals with energy-based device treatment to provide greater efficacy than using either modality alone. However, combination therapies must be clinically validated and have FDA clearance (in the U.S.) in order for manufacturers to make claims and at the present time, such published studies are limited. Over the next several years, however, most of the market leaders are expected to advance technologies and refine protocols incorporating energy-based treatment with topicals. Skin rejuvenation procedure volume will benefit from a growing installed base of systems and the continuing introduction of newer, more efficacious devices. Although rising competition will pressure treatment fees, as physicians increasingly utilize single-treatment ablative equipment, total procedure fees will rise from $4.9 billion in 2012 to more than $8.5 billion in 2017. It should be noted that skin tightening is covered in Medical Insight’s Body Shaping / Skin Tightening report series. miinews.com Medical Insight, Inc. 9 Mini-Report Skin Rejuvenation: Continually Advancing Technology Table 1 Top Skin Rejuvenation Devices, October 2013 Manufacturer Device Type Price Advanced Technology Laser Angelite IPL $35,000 Advanced Technology Laser Mini Laser IPL $30,000 Aerolase LightPod Neo X/XT Nd:YAG Laser $46,500 Aerolase LightPod Era X Er:YAG Laser $43,500 Alma Lasers Harmony AFT Pulsed Light $54,900+ Alma Lasers ARAMIS Er:Glass n/a Alma Lasers BURANE Er:YAG n/a Asclepion MeDioStar / MeDioStar NeXT Diode Laser n/a Asclepion MeDioStar Effect, Dermablate Effect, TattooStar Effect, RF plus Laser / Acoustic Wave / IPL / Diode Laser n/a Beijing Sincoheren Tony IPL IPL $6,200 Beijing Sincoheren Sienna IPL $5,600 Beijing Sincoheren RF-Vacuum RF $4,800 Beijing Sincoheren RF-Cool RF $4,300 Benev SkinStamp VMT Microneedle n/a Chromogenex Regenlite Pulsed Dye Laser n/a CoolTouch CT3 Plus Nd:YAG Laser $69,995 Intelligent Pulsed Light $76,000 Cutera Solera Opus/Limelight Cutera Xeo/Pearl Long Pulse Nd:YAG/Pulsed Light/ Infrared/YSGG $100,000 - $170,000 Cutera CoolGlide Vantage Nd:YAG Laser $70,000 Cutera VariLite KTP/Diode Laser $54,500 Cynosure RevLite EO Q-Switched Nd:YAG Laser with PhotoAcoustic Pulse $95,000 Cynosure Medlite C6 EO Q-Switched Nd:YAG Laser n/a Cynosure Accolade Q-switched Alexandrite $80,000 Cynosure Acclaim Nd:YAG Laser n/a Cynosure Affinity QS Q-switched Nd:YAG n/a Cynosure Cynergy with Multiplex Pulsed Dye/Nd:YAG $120,000 Cynosure Elite/Elite MPX Alexandrite/Nd:YAG Laser $110,000 DEKA PhotoSilk Plus Nd:YAG, PL $70,000 DEKA MiniSilk FT PL $35,000 DEKA Synchro HP, FT Nd:YAG, Er:YAG, PL $119,000 Eclipse EndyMed PRO Reverse Polarity $69,900 Eclipse Eclipse Air CCT Closed Chamber Technology (CCT) $69,900 Eclipse Eclipse SmoothCool IPL $69,900 Edge Systems HydraFacial MD Touch Multi Modality n/a Ellipse Ellipse MultiFlex IPL n/a Ellipse Ellipse I2PL IPL n/a Ellipse Ellipse Light SPT IPL n/a Ellman International Cortex CO2 / Er:YAG / Laser n/a miinews.com Medical Insight, Inc. 10 Mini-Report Skin Rejuvenation: Continually Advancing Technology Table 1 Cont’d Top Skin Rejuvenation Devices, October 2013 Manufacturer Device Type Price n/a Ellman International Tri-Lase Q-Switched Nd:YAG, Er:YAG Laser Ellman International Apex IPL, Er:YAG, Laser n/a Ellman International Pelleve Monopolar RF $34,995 Energist UltraPlus VPL Variable PL $35,995 Energist 610Frx CO2 Laser n/a Energist iPulse I200+ IPL $24,995 Energist i300 IPL $24,995 Energist ReGen High Power LED $19,995 Eufoton LASEmaR Diode Laser n/a Eufoton EULIGHT Plus PL n/a Focus Medical NaturaLight PL $59,900 Focus Medical NaturaLase QS4 Q-switched Nd:YAG Laser $93,900 - $115,000 Fotona XP MAX, Plus, Dualis, Fidelis Nd:YAG Laser $80,000 - $110,000 Fotona SP Dynamis, Plus, Dualis Nd:YAG/Er:YAG $110,000 Fotona QX MAX Q-switched Nd:YAG / KTP / red / yellow $80,000 General Project 3face Multi Modality n/a General Project Flash 1 Plus PL n/a General Project Med Flash II PL n/a Genesis Biosystems AccelaWave IPL $49,000 Genesis Biosystems AccelaFuze Combination Therapy System LED / Topical infusion $17,900 RF and IR n/a Hironic Hironic Hironic Ilooda Co. Ltd. Ilooda Co. Ltd. New MIDAS MIPL IPL n/a HIFU n/a Diode/IR/RF n/a OPS Diode n/a DOUBLO Symphony IRIS Jeisys SmoothCool PL n/a Ilooda Co. Ltd. Secret RF Microneedle n/a Ilooda Co. Ltd. VIKINI Diode Laser n/a INDUSTRA intenseIR High Powered IR Light n/a INDUSTRA IPL-SQ Square Wave Pulse IPL n/a Jeisys CIPL, P-Nain PL n/a Diode Laser $36,600 LASERING Velure S5 Lumenis M22 IPL $69,000 Lumiere Apollo TriPollar RF $50,000 Lutronic MOSAIC HP Erbium Fiber Laser n/a Lutronic Spectra Q-Switched Nd:YAG Laser n/a Miracle International n/a Nd:YAG Laser n/a Miracle International n/a IPL n/a Miracle International n/a RF na Miracle International n/a LED n/a miinews.com Medical Insight, Inc. 11 Mini-Report Skin Rejuvenation: Continually Advancing Technology Table 1 Cont’d Top Skin Rejuvenation Devices, October 2013 Manufacturer Device Type Price n/a Myoscience n/a Cryotherapy Norseld Dual Yellow Copper Bromide n/a Palomar StarLux 500 Platform Variable wavelength $80,000 Palomar Icon Variable wavelength $100,000 Palomar Artisan Variable wavelength $95,000 Pantec Biosolutions P.L.E.A.S.E. Professional Diode Pumped Er:YAG n/a Perfaction Energet Proprietary KineticHA technology n/a Maximus Dual energies – RF and Muscle Pollogen Quanta System Q-Plus R/T/A/C Q-switched Nd:YAG Laser $65,000 $57,995 - $99,995 Quanta System Eterna Giovinezza, Eterna Giovinezza Plus, Eterna Giovinezza Compact IPL n/a Radiancy/PhotoMedex Kona LHE n/a Sciton ClearScan Nd:YAG Module $29,000 Sciton BBL/BBLs PL $36,000 - $89,950 Sciton Contour TRL Tunable Resurfacing Laser $50,000 $200,000+ Sciton ThermaScan Sciton Nd:YAG Module $29,000 Modular $50,000 $200,000+ JOULE SharpLight Beamax IPL $39,000 SharpLight Formax Plus Dynamic Pulse Control $89,000 SharpLight Omnimax Dynamic Pulse Control $85,000 ShenZhen GSD Tech Co. Ltd. Biorad Unipolar RF n/a ShenZhen GSD Tech Co. Ltd. Silorad Bipolar RF n/a ShenZhen GSD Tech Co. Ltd. LBE Light Emitting Diode n/a ShenZhen GSD Tech Co. Ltd. sPTF PL n/a ShenZhen GSD Tech Co. Ltd. PTF Variable wavelength n/a Syneron Syneron eMax/eLight SR/SRA/WRA Optical energy and RF $59,900 - $75,900 Smoothbeam Diode Laser Syneron GentleLASE, GentleLASE Pro Alexandrite Laser $79,900 - $98,500 Syneron GentleYAG Nd:YAG Laser $79,900 - $109,900 Syneron SmoothPeel Er:YAG Laser TavTech JetPeel Water jet n/a IPL $24,900 Viora TRIOS $59,900 n/a Note: Does not include fractional skin rejuvenation systems. Source: Medical Insight, Inc. miinews.com Medical Insight, Inc. 12
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