講演会 - 九州大学

九州大学工学府 応用化学(分子)部門
教室セミナー
Pharmaceutical Formulations based on Poloxamers: Function
through Molecular Self-Assembly and Directed Assembly
Paschalis Alexandridis, PhD
UB Distinguished Professor, Department of Chemical and
Biological Engineering, University at Buffalo, The State
University of New York USA
平成28年12月6日(火) 14:40-16:00
伊都キャンパス W4 3F Room314(物質4番)
Amphiphilic polymers of the poly(ethylene oxide)-block-poly(propylene oxide) (PEO-PPO) family, commercially available as Pluronics or Poloxamers and
approved for pharmaceutical use, offer prime examples of self-assembling systems that find diverse applications. The presentation will utilize research
findings from our group and others to highlight how the fundamental aspects of Poloxamer block copolymer micellization and lyotropic liquid crystal
formation and nanostructure in aqueous media, inform the formulation of Poloxamers applied to stabilizing oil-in-water emulsions and colloidal
dispersions and to forming stable “frozen” micellar nanoparticles with high loading of actives for drug delivery.
連絡先: 後藤 雅宏
九州大学大学院工学研究院 応用化学(分子)部門
Tel: 092-802-2806 e-mail: [email protected]