With drugs - Mahidol University

Preop.assessment
Somsak aree-wattana, M.D.
Phongthara Vichitvejpaisal, M.D.
Department of Anesthesiology
Faculty of Medicine Siriraj Hospital
Mahidol University
Objectives to see the patients
1.
2.
3.
4.
5.
6.
Patient’s data
Tests and consultations
Education about anesthesia
Care plans
Informed consent
Effective resources utilization
Physical Status Classification
Physical Status Modified Slightly from USA
Definition
1.The patient has no systemic disease, including the
pathologic process for which operation is needed,
which is localized.
2.The patient suffers mild or moderate systemic disease
due either to the surgical condition or to a concomitant
disease.
3. Severe systemic disease limits the patient’s activity.
Physical Status Classification
Physical Status Modified Slightly from USA
Definition (cont.)
4.Severe life-threatening disease markedly limits the
patient.
5.The moribund patient has a 50 percent 24-hour
mortality, regardless of the planned operation.
6.The patient is declared dead and will undergo operation
for organ donation.
7.When the patient requires emergency operation, and E
is appended to the PS number.
Physical Status Classification
American Society of Anesthesiologists (ASA)
Class I ผูป
้ ่วยสุขภาพดี เข้ารับการผ่าตัด elective surgery
Class II ผู้ป่วยที่มีโรคประจาตัวเล็กน้อย
Class III ผู้ป่วยที่มีโรคประจาตัวรุนแรงจนจากัดการเคลื่อนไหว
แต่ยังทากิจวัตรได้บ้าง
Class IV ผูป
้ ่วยที่มีโรคประจาตัวที่ทาให้เกิดความพิการเป็นอันตรายต่อชีวต
ิ
Class V ผูป
้ ่วยหนักที่คาดว่าอาจมีชวี ิตอยู่ไม่ถึง 24 ชั่วโมง
แม้จะได้หรือไม่ได้รับการผ่าตัด
Objective of preanesthetic evaluation
 Review database
medical history
consultations
laboratory and diagnostic studies
 Perform physical examination directed at anesthetic
concerns
 Develop anesthesia management plan
 Obtain consent
 Establish doctor-patient relationship
Review of Medical Records

relevant medical history

Previous consultations

Previous diagnostic test

Prior anesthetic records
History and Physical Examination

History


Present illness
Past medical history
-
-
Medical problem with brief history
Medication
Allergy
Past surgical and anesthetic history
Family history
Social history
Review of system
General Review of Organ System
Function








General
Skin
Head
Eye and ears
Nose and throat
Mouth
Cardiac
respiratory








Gastrointestinal
Urinary
Female
Extremities
Neurologic
Endocrine
Psychiatric
prosthetics
Physical examination







Vital signs
Dental examination
Airway examination
Pulmonary examination
Cardiac examination
Neurologic and musculoskeletal examination
Others
Preop Evaluation
Laboratory Testing
Strategy for Preoperative Testing
Preoperative
condition
HGB
M
F
Precedure with
blood loss




WBC
PT/
PTT
PLT
BT
Electrol
yte
Creat/
BUN
Bl.
Glu
AST/A
LK
Chost
flim
ECG
Age <40

Age 40-49

Age 50-55

Age : 65



Cardiovascular
disease

Pulmonary
disease
Malignancy
Randlation
therapy

T/S

Procedure
without blood
loss
Neonates
Preg









Laboratory Testing
Strategy for Preoperative Testing (cont.)
Preoperative
condition
HGB
M
WBC
F
Hepatic disease
PT/
PTT
PLT
BT
Electrol
yte
Creat/
BUN
Bl.
Glu

ECG





Diabetes









Possible
pregnancy

Diuretic use


Digoxin use


Steroid use

Anticoagulant
use
CNS disease
Preg

Blooding
disorder
Smoking >20
pack-yr
Chost
flim

Exposure to
hepatitis
Renal disease
AST/A
LK










T/S

Aspiration of gastric contents
- fasting
- gastric anti-secretory agents
- H2 blocker
- PGE1
- Omeprazole

Aspiration of gastric contents
- ondansetron
- metoclopramide
- droperidol
Anesthetic impression and Plan
Components:
1.
Brief summary of the patient’s history and physical
findings as they pertain to anesthesia management,
organized in a problem list, parallelling any existing
problem list used by the primary physician
2.
Planned anesthetic technique including special
techniques discussed (e.g. fiberoptic intubation, invasive
monitoring)
3.
Planned postoperative pain management, if appropriate
Anesthetic impression and Plan
Components:
4. Special postoeprative issues when indicated (e.g., ICU stay)
5. Request for further medical evaluation if indicated
6. Statement of risks, informed consent, and statement the all
questions were answered
7. Physical status classification and brief justification
Informed Consent
Inform
• anesthetic options
risks
benefits
appropriate information
written documentation
Premedication
 Common problems amenable to treatment before anesthesia and
operation
Anxiety
Amnesia
Pain
Salivation and airway secretions
Vagal reflexes
Hypertensive response
Aspiration of gastric contents
nausea and vomiting
Infection
Reaction to iv contrast media, latex
Continuation of preoperative therapy
Alleviating anxiety


Without drugs
With drugs
Drug Group
Drug Name
Drug dose
Route
Anticholinergics
Atropine
0.2-0.6
IM/TV
Glycopyrrolate
0.2-0.3
IM/TV
Scopolamine
0.2-0.4
IM/TV
Gastrokinetics
Metoclopramide
10-20
Oral, IM/TV
H2 antagonists
Cimetidine
300
Oral, IM/TV
Alpha-2-agonists
Clonidine
0.20-0.40
Oral
5-HT antagonist
Ondansetron
4.0-8.0
IM/TV
Alleviating anxiety
Without drugs
 With drugs
Drug dose
Drug Group
Benzodilazepines
Diazepam
Flurazepam
Lorazepam
Midazolam
Triazolam
Tranqullizers
Droperidol
Antihistamines
Diphenhydramine
Hydroxyzine
Opioids
Fentanyl
Hydromorphone
Mophrine
Meperidine

Drug dose
5-20
15-30
2-4
2-5
0.125-0.250
0.625-2.5
25-75
50-100
0.05-0.2
1.0-2.0
5-15
50-100
Route
Oral
Oral
Oral, IM
IM/TV
Oral
IM/TV
Oral, IM/TV
IM
IM/TV
IM/TV
IM/TV
IM/TV
Amnesia
Anterograde amnesia
- midazolam
- lorazepam
- scopolamine (0.4-0.6 mg iv)
Analgesia
- opioids
Reducing salivation and bronchial
secretions
- Glucopyrrolate 0.2-0.4 mg iv/im

Blocking vagal reflexes
- atropine - 0.2-0.4 mg iv/im
- 0.01 mg/kg iv (infant)

Prevention of hypertension
- continue antihypertensive drug
adequate depth of anesthesia
premedication - opioid
- a1b sympathetic blocker
- a2sympathetic blocker
; clonidine

Anticonvulsants
- continue anticonvulsants
premedication with benzodiazepines
Continuation of preoperative therapy
Antihypertensive drug
nitrate drug
bronchodilator
diuretics
antidepressants
glucocorticoids
insulin regimen
Premedication to prevent infection
Prophylaxis of Endocarditis
1. For dental, oral or upper respiratory procedures:
amoxicilline 3.0 g PO 1 hour
For amoxicillin – PCN allergic patients:
Erythromycin 800 mg PO, 2 hours preoperatively
And 400 mg 6 hours after initial dose of clindamycin
300 mg PO 1 hour preoperatively and 150 mg 6 hours
after initial dose
Premedication to prevent infection
Prophylaxis of Endocarditis (cont.)
2. Altematives for dental, oral or upper respiratory
procedures: ampcillin 2.0 g IV/IM 30 min preoperatively; then 6
hours later, ampicillin 1.0 g IV/IM or amoxicillin 1.5 g PO. A
second option: clindamycin 300 mg IV 30 min preoperatively,
then in 6 hours, 150 mg IV.
Premedication to prevent infection
Prophylaxis of Endocarditis (cont.)
3.For GVGU procedures: IV/IM ampicilin 2.0 g plus
gentamicin 1.5 mg/kg (not to exceed 80 mg) 30 minutes
preoperatively; then repeat parenteral ampicilin and
gentamicin 8 hours later, or substitute amoxicilin 1.5 g PO 6
hours later.
For ampicilin/amoxicilin/PCN allergic patients:
vancomycin and gentamicin: IV vancomycin 1.0 g plus IV/IM
gentamicin 1.5 mg/kg (not to exceed 80 mg) 1 hour
preoperatively; may repeat 8 hours after initital dose
Thank you for your attention