scientific program

SCIENTIFIC PROGRAM
Saturday, May 28th, 2016
12:00 Registration and check-in
at the Elsa-Brändström Conference Center
15:00 Opening session
GILLES MITHIEUX (LYON)
Gut-brain neural circuits linking microbiota metabolites and glucose control
PATRICE CANI (BRUSSELS)
Interactions between gut microbes and host cells: focus on obesity and diabetes
coffee break
17:00 DIRK HALLER (FREISING)
Gut feelings in metabolic disorders
VANESSA RIDAURA (BETHESDA)
The crosstalk between diet, resident commensals and skin immunity
reception and dinner
Sunday, May 29th, 2016
8:30 Session 1
ROBERT CAESAR (GOTHENBURG)
Cross-talk between gut microbiota and dietary components affects host metabolism and inflammation
MICHAEL BLAUT (POTSDAM)
Diet-dependent modulation of host energy metabolism by intestinal bacteria
short communications
THOMAS CLAVEL (MUNICH)
Gut bacteria of the family Coriobacteriaceae increase white adipose tissue deposition in mice
JOHN INGRAM (AUCKLAND)
Activation of gastrointestinal bitter taste receptors suppresses food intake and stimulates CCK, GLP-1 and PYY
secretion in healthy men
10:15 Poster session 1
(coffee will be served in front of the poster room)
12:30 lunch
14:00 Session 2
MICHAEL RISTOW (ZURICH)
Metabolic control of aging
JOHN SPEAKMAN (BEIJING)
Is the effect of calorie restriction on lifespan actually due to protein restriction?
TIM SCHULZ (POTSDAM)
The role of the adipocytic lineage in the development of age-related metabolic disorders
coffee break
16:15 DANIELA COTA (BORDEAUX)
mTORC1 and endocannabinoid signaling set hypothalamic melanocortin tone to regulate feeding
MATTHEW RODEHEFFER (NEW HAVEN)
Nutritional regulation of adipogenesis in obesity
short communications
MANDY STADION (POTSDAM)
Gender-specific effects of Ifi202b on obesity and glucose homoeostasis
ADAM ROSE (HEIDELBERG)
Dietary protein dilution promotes metabolic health via NEAA-insufficiency induced liver FGF21
18:00 dinner
20:00 Evening session
SUSANNE KLAUS (POTSDAM)
Short chain fatty acids in the regulation of liver metabolism and energy homeostasis
BART STAELS (LILLE)
Non-alcoholic fatty liver disease control by PPARs
HENRIETTE UHLENHAUT (MUNICH)
GR: genomic road maps of inflammation and metabolism
Monday, May 30th, 2016
8:30 Session 3
JOSEPH NADEAU (SEATTLE)
Genetic and phenotypic architecture of diet-induced metabolic diseases and cancers
PER-OLOF BERGGREN (STOCKHOLM)
Pancreatic islet cell physiology/pathophysiology at a glance
ALAN ATTIE (MADISON)
The genetic architecture of insulin secretion
coffee break
10:45 ANNETTE SCHÜRMANN (POTSDAM)
Identification of obesity and diabetes genes in mice as translational research strategy
CHARLOTTE LING (MALMÖ)
Does epigenetic variation play a role in the pathogenesis of type 2 diabetes?
short communication
ALEXANDROS VEGIOPOULOS (HEIDELBERG)
Microenvironmental regulation of nutrition-driven adipocyte progenitor responses in early-onset obesity
12:30 lunch
14:00 Session 4
BARBARA CANNON (STOCKHOLM)
Metabolic control of the expression and activity of UCP1
MATTHIAS TSCHÖP (MUNICH)
Mimicking cold exposure to treat metabolic disease
short communication
CLARA JOHN (HAMBURG)
Brown and beige adipocyte lipoprotein lipase activity controls metabolic flux through the HDL compartment
16:00 sight-seeing
Tuesday, May 31st, 2016
8:30 Session 5
CHRISTIAN WOLFRUM (ZURICH)
Regulation of brown fat formation and function
JAN NEDERGAARD (STOCKHOLM)
The significance of brown adipose tissue for metabolic control
ALEXANDER PFEIFER (BONN)
Autocrine and paracrine signaling in brown fat
10:15 Poster session 2
(coffee will be served in front of the poster room)
12:30 lunch
14:00 Session 6
HANS-ULRICH HÄRING (TÜBINGEN)
Obesity and brain insulin resistance: cause or consequence
YU-HUA TSENG (BOSTON)
Cold-induced lipid dynamics in brown, beige and white adipose tissue
short communications
THOMAS LUTZ (ZURICH)
The action of the amylin analogue pramlintide released from automated lipid-sensing receptor cells on food intake and
body weight gain in high fat fed rats
NICHOLAS DiPATRIZIO (RIVERSIDE)
Dysregulation of endocannabinoid signaling pathways in diet-induced obesity
coffee break
16:15 CLOSING LECTURE
STEFAN OFFERMANNS (BAD NAUHEIM)
Metabolite GPCRs – regulation of adipocyte, immune and β-cell function
departure
Poster presentations
Posters are shown in the conference room on the top floor of the guest house. Posters should be mounted on Saturday and left
throughout the meeting.
1
Christian Baumeier, Sophie Saussenthaler, Anne Kammel, Annette Schürmann & Robert Schwenk (Potsdam, Munich).
Methylation of hepatic Dpp4 in young C57BL/6J mice modulates transcriptional activation by glucose and associates with obesity.
2
Thomas Clavel, Sarah Just, Katrin Wegner, Philippe Gerard, Patricia Lepage & Sascha Rohn (Munich, Hamburg, Jouy-enJosas). Gut bacteria of the family Coriobacteriaceae increase white adipose tissue deposition in mice.
3
Petia Doytcheva, Jeremy Deuel, Dominik Schaer, Thomas Lüscher, Thomas Lutz, Christian Wolfrum & Elena Osto (Zurich).
Roux-en-Y gastric bypass improves HDL-mediated cholesterol efflux: the functional relevance of changes in HDL subclasses
profile and phospholipid composition.
4
Sabrina Gohlke, Lukasz Japtok, Jochen Steinbring, Eberhard Krause, Heike Stephanowitz, Burkard Kleuser & Tim Schulz
(Potsdam, Munich, Berlin). Proteome and lipidome profiling reveals functional biomarkers of brown adipose tissue aging.
5
Silke Heinzmann & Philippe Schmitt-Kopplin (Munich, Freising). Spatial gut differences and cross-species comparison of fecal
metabolite profiles via metabolite profiling analysis.
6
Anne-Marie Jank, Antonia Graja, Markus Köhler, Deike Hesse, Wenke Jonas, Annette Schürmann, Manfred Gessler & Tim
Schulz (Potsdam, Munich, Würzburg). Age-related changes in cell-to-cell communication impair brown adipogenesis.
7
Clara John, Alexander Bartelt, Anna Worthmann, Nicola Schaltenberg, Julia Schmidt, Philipp Werner, Maria Trusch, Klaus
Tödter, Markus Fischer, Ludger Scheja & Jörg Heeren (Hamburg, Boston). Brown and beige adipocyte lipoprotein lipase activity
controls metabolic flux through the HDL compartment.
8
Anne Kamitz, Nicole Hallahan, Ralph Burkhardt, Markus Jähnert, Reinhart Kluge, Wenke Jonas, Hans-Georg Joost & Annette
Schürmann (Potsdam, Leipzig). Characterization of Ltg/NZO, a novel Liver Fat Quantitative Trait Locus (QTL) in an NZOxB6
backcross.
9
Juliane Kasch, Sara Schumann, Isabel Walter & Susanne Klaus (Potsdam). Consequences of maternal nutrition for exercise
efficiency, muscle metabolism, and obesity susceptibility of the offspring.
10 Oliver Kluth, Daniela Matzke, Anne Kamitz, Markus Jähnert, Harald Staiger, Hans-Ulrich Häring, Hans-Georg Joost & Annette
Schürmann (Potsdam, Munich, Tübingen). Identification and functional validation of four diabetes genes in mice.
11 Adriano Maida, Annika Zota, Tjeerd Sijmonsma, Kerstin Stemmer, Bente Kiens, Stephan Herzig & Adam Rose (Heidelberg,
Munich, Copenhagen). Dietary protein dilution promotes metabolic health via NEAA-insufficiency induced liver FGF21.
12 Irina Meln, Gretchen Wolff, Irem Bayindir-Buchhalter, Sarah Lerch, Jürgen Reymann, Holger Erfle & Alexandros Vegiopoulos
(Heidelberg). Microenvironmental regulation of nutrition-driven adipocyte progenitor responses in early-onset obesity.
13 Mario Ost, Verena Coleman, Anja Voigt, Evert van Schothorst, Susanne Keipert, Inge van der Stelt, Sebastian Ringel, Antonia
Graja, Thomas Ambrosi, Anna Kipp, Martin Jastroch, Tim Schulz, Jaap Keijer & Susanne Klaus (Potsdam, Wageningen, Munich).
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.
14 Marie Roch, Christelle Le Foll & Thomas Lutz (Zurich). The action of the amylin analogue pramlintide released from automated
lipid-sensing receptor cells on food intake and body weight gain in high fat fed rats.
15 Maria Rödiger, Martin Werno, Deike Hesse, Nina Wettschureck, Stefan Offermanns & Annette Schürmann (Potsdam, Bad
Nauheim). Identification of monomeric GTPases involved in trafficking and secretion of adiponectin.
16 Mandy Stadion, Kristin Schwerbel, Heike Vogel, Hans-Georg Joost & Annette Schürmann (Potsdam). Gender-specific effects of
Ifi202b on obesity and glucose homoeostasis.
17 Jochen Steinbring, Sabrina Gohlke, Heike Stephanowitz, Antonia Graja, Anne-Marie Jank, Eberhard Krause & Tim Schulz
(Potsdam, Berlin, Munich). Age-related changes of the adipose tissue microenvironment and its effects on brown adipogenesis.
18 Robert Steinert, Maria Landrock, Scott Standfield, Michael Horowitz & Christine Feinle-Bisset (Basel, Adelaide).The role of gut
motor and hormone function in the satiating and glucoregulatory capacity of amino acids in healthy men.
19 Alesia Walker & Philippe Schmitt-Kopplin (Munich, Freising). Metabolomics to decipher gut microbiota derived metabolites.
20 Karolin Weitkunat, Sara Schumann, Michael Blaut & Susanne Klaus (Potsdam). Long-term supplementation of dietary inulin and
short-chain fatty acids (SCFA) suppress high-fat diet-induced obesity in C57BL/6J mice.
21 Anna Worthmann, Clara John, Miriam Baguhl, Malte Rühlemann, Femke-Anouska Heinsen, Alexander Bartelt, Andre Franke,
Ludger Scheja & Jörg Heeren (Hamburg). Cold regulated bile acid synthesis shapes the gut microbiome.
22 Martin Werno, Bomee Chung, Alexander Jaschke, Magnus Hartmann & Annette Schürmann (Potsdam). Impact of the GTPase
ARFRP1 on chylomicron secretion and lipidation.
23 John Ingram, Edward Walker, Malcolm Pahl, Kim Lo, Hyun Shin, Claudia Lang, Mark Wohlers, Sally Poppitt & Kevin Sutton
(Auckland). Activation of gastrointestinal bitter taste receptors suppresses food intake and stimulates CCK, GLP-1 and PYY
secretion in healthy men.
24 Nicholas DiPatrizio & Donovan Argueta (Riverside). Dysregulation of endocannabinoid signaling pathways in diet-induced
obesity.

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