＜繊維学会西部支部外国人講演会＞

＜繊維学会西部支部外国人講演会＞
"Bacterial Cellulose ： A Versatile Nano-medical Functional Materials"
中国・Huazhong University of Science & Technology（華中科技大学）
生命科学工学部 Guang Yang（楊光）教授
日時：2014 年 9 月 18 日（木曜日）午後 1 時 30 分より 1 時間程度（質疑込）
場所：九州大学箱崎キャンパス農学部 21 世紀プラザ Ⅰ室
"Bacterial Cellulose ： A Versatile Nano-medical Functional Materials"
Professor Guang Yang
Department of Biomedical Engineering, College of Life Science and Technology,
Huazhong University of Science and Technology, Wuhan 430074, PR
China National Engineering Research Center for Nano-Medicine, Huazhong
University of Science and Technology, Wuhan 430074, PR China;
Abstract:
Bacterial cellulose (BC) is secreted by microorganism. Its biocompatibility, mechanical strength,
chemical and morphologic controllability 1 make it a natural choice for adoption in biomedical fields,
including use as biomaterial for wound dressing 2, artificial blood vessels, vascular grafts, scaffolds
for tissue engineering and controlled-release drug carriers 3. More than that, BC is a natural hydrogel,
its high water content can carry other monomeric, reactive and potentially polymerizable species into
BC’s inner network, essentially occupying the void volume and interacting with chain segments or
pendant moieties of the BC. Therefore, Varity of composites based BC were synthesized and expand
the application of BC. BC composites are primarily synthesized through in situ addition of
reinforcement materials to BC synthetic media or the ex situ penetration of such materials into BC
microfibrils. In our group’s research, BC combine with biomacromolecules such as chitosan,
hyaluronic acid, collagen, silk fibroin and so on, can be used in wound dressing
4
and cosmetic. BC
combine with Poly (NIPAM-co-BMA) 5, which has thermoresponsive property, suitable for vascular
embolization interventional therapy. BC combine with carbon nanotubes or conductive polymers
6-7,
which has electractive property, can be used as flexible supercapacitor, electrodes, and have potential
to be used to build a biology-device interface to produce implantable biosensors, electrostimulated
drug release devices, and implantable devices for personalized and regenerative medicine.
References:
1) Shi Z, Zhang Y, Phillips GO, Yang G. (2014). Utilization of bacterial cellulose in food. Food
Hydrocolloid.;35: 539-45.
2) Fu L, Zhang Y, Li C, Wu Z, Zhuo Q, Huang X, Qiu G, Zhou P, Yang G.(2012) Skin tissue repair
materials from bacterial cellulose by a multilayer fermentation method. J Mater Chem. 22: 12349-57.
3) Huang L, Chen X, Thanh XN, Tang H, Zhang L, Yang G.(2013) Nano-cellulose 3D-networks as
controlled-release drug carriers. J Mater Chem B. 1: 2976-84.
4) Fu L, Zhang J, Yang G.(2013) Present status and applications of bacterial cellulose-based materials
for skin tissue repair. Carbohyd Polym. 92: 1432-42.
5) Wu L, Zhou H, Sun H, Zhao Y, Yang X, Cheng SZ, Yang G.(2013) Thermoresponsive Bacterial
Cellulose Whisker/Poly (NIPAM-co-BMA) Nanogel Complexes: Synthesis, Characterization, and
Biological Evaluation. Biomacromolecules. 14: 1078-84.
6) Shi Z, Phillips GO, Yang G. (2013) Nanocellulose electroconductive composites. Nanoscale. 5: 3194201.
7) Shi Z, Li Y, Chen X, Han H, Yang G.(2014) Double network bacterial cellulose hydrogel to build a
biology-device interface. Nanoscale. 6: 970-7.
お問い合わせ先：
九州大学大学院農学研究院バイオマテリアルデザイン分野（研究室）
近藤哲男
E-mail: [email protected]
Tel: 092-642-2997

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