Version 21 May 2014 Tuesday 27 May 2014 9:00 - 10:00

Version 21 May 2014
Tuesday 27 May 2014
9:00 - 10:00 Registration & Coffee / Company Market
10:00 - 10:10 Opening & Welcome (Studio-3)
10:10 - 10:55 Keynote speaker: Cees Dekker, prof. Bionanoscience, TU Delft (Studio-3)
Nanopores and nanostructures for research from single molecules to bacteria
10:55 - 11:05 Zilveren Zandloper Award Innovation (Studio-3)
11:10 - 12:30
Parallel Session-1
Session-1A: Studio-3
Session-1B: Bach 1-2
Microbial Systems Biology & Synthetic Biology
Process Design
Chair: Hans Roubos (DSM)
11:10-11:15 Intro
Company pitch by Marco Siemerink (Infors HT/
MicCell)
12:30 - 13:55
12:45 - 13:30
13:55 - 14:40
14:45 - 16:05
Chair: Arthur Janse (DSM)
Intro
Company pitch by Erik Kakes (Applikon)
11:15-11:40 Greg Bokinsky (TU Delft)
Nico Oosterhuis (CELLution Biotech )
Engineering E. coli for turning plants to fuels in one step Single-use bioreactors for microbial
application: feasibility and recent advances
11:40-12:05 Pascale Daran-Lapujade (TU Delft)
Alexander Hanke (TU Delft)
Construction of synthetic glycolytic pathways
Comprehensive high-throughput multiin Saccharomyces cerevisiae
dimensional liquid chromatography for the
characterization of complex biological mixtures
12:05-12:30 Matthias Heinemann (RU Groningen)
Ellen Slegers (Wageningen University)
Flux-signaling and flux-dependent regulation
Scenario studies as tool for process design
of metabolism
Lunch, Poster Session (presenters of even numbers present) and Company Market
General Assembly (ALV) of members of the NBV in Bach 1-2
Keynote speaker: Casper Vroemen, head of research, Dupont Industrial Biosciences (Studio-3)
Industrial Biotechnology at DuPont Industrial BioSciences – The science behind sustainable solutions
Parallel Sessions (coffee available)
Parallel Session-2
Session-2A: Studio-3
Session-2B: Bach 1
Microbial Systems Biology & Synthetic Biology
Product Isolation / Design for Products and
Processes
Session-1C: Bach 3-4
Environmental Biotechnology / Process Design for
Environmental Biotech applications
Chair: Peter van der Maas (WLN)
Intro
Company pitch by Tangir Ahamed (Marlin
biopurification)
High-throughput process development at Marlin
Biopurification
Bert Geurkink (RU Groningen)
A practical approach for mapping metagenomic
data from complex microbial communities
Nora Sutton (Wageningen UR)
Biomolecular tools for assessing biodegradation of
organic micropollutants in water resources
Perry van der Marel (WLN, North Water)
Interesting behaviours in an conventional wastewater
treatment plant
Session-2C: Bach 3-4
Carreer Workshop
Chair: Hans Roubos (DSM)
14:45-14:50 Intro
Company pitch by Andreas Rowher (Roche
Diagnostics)
Improving cell culture monitoring with Cedex Analyzers Cedex Bio, Cedex Bio HT and Cedex HiRes
Chair: Maarten Pennings (Tarpon Biosystems)
Intro
Company pitch by Edwin Telgenkamp (GEA)
Chair: Paul Rulkens (DSM)
Intro
Company pitch by Andrea Thiele (HAN)
Algae downstream processing from a single source
Kick-start your career with the part-time
Master Molecular
14:50-15:15 Ruben Kok (DTL)
DTL Dutch Techcentre for Life Sciences:
building technology and data expertise bridges across
sectors to establish an integrated life science research
infrastructure
15:15-15:40 Bas Teusink (VU/NISB)
In silico probing of the full metabolic
potential of an industrial microoragnism for improved
medium design
15:40-16:05 Sacha van Hijum (Radboud UMC/ NIZO/TIFN)
Strain level genomics of lactic acid bacteria
Edwin Zondervan (TU Eindhoven)
Wouter de Jong (Bio-Itech)
A process systems engineering approach to process and Erik Kakes (Applikon Biotechnology)
Marijke Westra (VO)
product design
Cees Sagt (DSM)
Erik Benjamins (Friesland Campina)
Michiel Noback (Hanze University of Applied Sciences)
Marcel Ottens (TU Delft)
High Throughput Biopharmaceutical Process
Development
Michel Eppink (Synthon / WUR)
Biorefinery of Microalgae: Mild separation technologies
for complex biomolecules
16:10 - 16:20 Zilveren Zandloper Award Education (Studio-3)
16:20 - 17:05 Keynote speaker: Marcel Wubbolts, Chief Technology Officer, DSM (Studio-3)
Is Europe a Lost Continent for the Biobased Economy?
17:05 - 18:00 Drinks, Poster Session (presenters of odd numbers present) and Company Market
18:00
Buffet
21:00
End of day-1
Session-2D: Bach 2
Societal Aspects of Biotechnology Workshop /
Debating biotechnology in The Netherlands:
past, present and future
Chair: Virgil Rerimassie (Rathenau Institute)
Intro
Company pitch
Nadine Bongaerts (Biotecture)
Laurens Landeweerd (TU Delft)
Virgil Rerimassie (Rathenau Instituut)
Jan Wisse (Bayer)
Version 21 May 2014
Wednesday 28 May 2014
8:30 - 9:00 Registration & Coffee / Company Market
9:00 - 9:45 Keynote speaker: Cees Buisman Executive board member Wetsus/ Professor Environmental Technology, Wageningen University (Studio-3)
From blue sky thinking to market introductions in biological water technology
9:45 - 10:00 Poster Pitches (Studio-3)
10:00 - 10:30 Coffee/tea break, Poster Session and Company Market
10:30 - 11:50
Parallel session-3
Session-3A: Studio-3
Session-3B: Bach 1-2
Session-3C: Bach 3-4
Microbial Physiology
Process Design
Organism Design
Chair: Gertjan Euverink (RU Groningen)
Chair: Hans van den Berg (Finesse)
Chair: Vitor Martins dos Santos (WUR)
10:30-10:35 Intro
Intro
Intro
Company pitch
Company pitch by Robin Thibault (Charter
Company pitch by Marco Wanders (Euretos)
Medical)
Delivering solutions through customer-driven
innovation
10:35-11:00 Peter Mooij (TU Delft)
Lenneke de Winter (Wageningen University,
Walter Pirovano (BaseClear)
AlgaeParc)
Survival of the Fattest – A microbial community
Microalgae on a Timeschedule: Circadian Rhythms in
The BaseClear Genome Browser (BGB)TM: an
engineering approach to select highly productive
the Cell Cycle and Biomass Composition of Neochloris
easy online platform for high-throughput screening of
microalgae species
oleoabundans
bacterial and fungal genomes
11:00-11:25 Frank Bruggeman (VU Amsterdam)
Richele Wind (HAN BioCentre)
Packo Lamers (Wageningen Unversity,
AlgaeParc)
For rational redesign of microorganisms we have
Yeast oil: production and application
Microalgal lipid production - bridging the yield gap
to understand what they are designed for
11:25-11:50 Oscar Kuipers (RU Groningen)
Caroline Paul (TU Delft)
Diana Pronk (DSM)
Design and production of novel
From styrene to enantiopure phenylethanol
HT screening technologies, an introduction in screening
antimicrobials
derivatives: a chemo-enzymatic cascade
tools for improving cell factories.
11:50 - 12:45 Lunch, Poster Session and Company Market
12:00 - 12:30 Meeting NBV board with contact persons working groups in Bach 1-2
12:45 - 14:05
Parallel session-4
Session-4A: Studio-3
Session-4B: Bach 1-2
Session-4C: Bach 3-4
Cell Design
Cell & Fermentation Technology
Applied Biocatalysis / Enzyme by Design
Chair: Ruud Weusthuis (WUR)
Chair: Mathieu Streefland (WUR)
Chair: Isabel Arends (TU Delft)
12:45-12:50 Intro
Intro
Intro
Company pitch by Jeroen Schouwenberg
Company pitch by Hans van den Berg (Finesse)
Company pitch
(Eppendorf)
Universal Controllers and SmartFactories
12:50-13:15 Ruud Weusthuis (Wageningen University)
Dinja Oosterhoff (Intravacc)
Rene de Jong (DSM)
To low cost fermentation processes: from
Screening of human suspension cell lines for the
Engineering Nature’s enzyme repertoire for food
reactor engineering to cell engineering
capacity to support virus replication
and pharma
13:15-13:40 Ilse Remmers (Wageningen University)
Henk Noorman (DSM/TU Delft)
Hugo van Beek (RU Groningen)
Lipid production in Phaeodactylum tricornutum
Bioreactor scale-up and scale-down: faster
Stabilization of cyclohexanone
under simulated outdoor conditions
by computation
monooxygenase by computational design
13:40-14:05 Lisette Dedens (Pall Life Sciences)
Bram Bout (Bioceros)
Tom van den Bergh (Bio-Prodict)
Kinetic Analysis of Antibody Binding to an
Development of Robust Production Cell Lines:
Massive protein superfamily data integration
Expressed Membrane Protein on Captured Lipoparticles a Dutch contribution
applied to smart library design
14:05 - 14:30 Coffee/tea break
14:30 - 14:35 Poster award (Studio-3)
14:35 - 15:20 Keynote speaker: Mark Post Professor Vascular physiology, Maastricht University (Studio-3)
Stem cells: Therapy or Food?
15:20 - 15:25 Closure
15:25 - 16:00 Drinks
Posters
# Name
1 Christien Lokman
2 Fean D. Sarian
3 Marjon van Es
4 Xiao Pan
5 Elleke Bosma
6 Graciela Mitsue Leon Saiki
7 Dorett Odoni
8 Hanka Venselaar
9 Petra Meeuwse
10 Elina Klijs
11 Martin Velthuis
12 Silvia M. Pirrung
13 Alexander Lubsch
Affiliation
HAN BioCentre
University of Groningen
Algae Parc/Wageningen University
Wageningen University
Wageningen University
Wageningen University
Wageningen University
Radboud UMC
Dyadic Netherlands
Thermo Fisher Scientific –
BAC BV
University of Groningen
26 Stamatios Damalas
TU Delft
Royal Netherlands Institute
for Sea Research
TU Delft
University of Groningen
University of Groningen
University of Groningen
Wageningen University
Wageningen University
Wageningen University
Wageningen University
Thermo Fisher Scientific – BAC BV
University of Groningen
University of Groningen
LACDR, Division of Pharmacology,
Leiden
Wageningen University
27
28
29
30
31
32
33
34
Wageningen University
Wageningen University
Wageningen University
University of Groningen
TU Delft
University of Groningen
ModiQuest Research
Wageningen University
14
15
16
17
18
19
20
21
22
23
24
25
Marcelo Silva
Marc van der Maarel
Marc van der Maarel
Marc van der Maarel
Jasper Sloothaak
Kiira Vuoristo
Mathieu Streefland
Vincent van der Vlist
Hendrik Adams
Miftahul Ilmi
Cyntia M. Palacio
Robin Hartman
Rupali Desai
Tim de Mooij
Juan Antonio Tamayo-Ramos
Jimmy Omonoy
David Mendez Sevillano
Alessandro R. Ferrari
Nienke Smits
Abhishek Gupta
35 Kees van der Graaf
Sulfateq B.V.
Version 21 May 2014
Title
Identification of microorganisms with antifungal activity against T. agrresivum and other “Weed” fungi in mushroom compost
Characterization of an intracellular -amylase, BmaN3, from marine bacteria Bacillus megaterium NL3
The influence of cultivation conditions on cell strength and extractability of microalgae
Fed-batch media screening for CHO cells
Isolation, characterization and metabolic engineering of a thermophilic Bacillus for green chemical production
Dynamics of chloroplast metabolism in Chlamydomonas reinhardtii
Construction of FRET biosensors for intracellular metabolite detection in Aspergillus niger
NEWPROT: A protein engineering portal
High-level production of plant cell wall degrading enzymes with Myceliophtora thermophila C1
CaptureSelect™ C-tag; a novel purification platform for C-terminal tagged proteins
Design of an on-line biosensor to detect genotoxic compounds in surface water with continuous growing genetically modified
luminescent bacteria
A new Paradigm in Bio Purification Process Development
Seaweeds as a source of high-value products
Recovery and purification of fermentation-based polyphenols
Isolation of the sulphated carbohydrate ulvan from the seaweed Ulva lactuca
Structure of the storage -glucan from the thermoacidophilic red alga Galdieria sulphuraria
Kinetic characterization of Aspergillus niger chitinase CfcI using a HPAEC-PAD method for native chitin oligosaccharides
Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
Itaconic Acid Production in Escherichia coli By Overexpression of Citrate Synthase, Aconitase, and Cis -Aconitate Decarboxylase
A Process Analytical Technology (PAT) strategy to improve manufacturing excellence of a perfusion PER.C6 ® cultivation process
Use of an enzymatic catalyst for the synthesis of furan based polymers
CaptureSelect™ Technology: Introducing One-Step Selectivity in the Purification of Biological Products
Jatropha curcas L. Seed-Cake as Substrate for Fungal Enzymes Production in Submerged Fermentation
Redox self-sufficient biocatalytic network for production of aliphatic amines
Prediction of human brain target site concentrations: the preclinical approach using microdialysis and in silico modeling
Verification of the activity and strength of a set of constitutive orthogonal promoters in Pseudomonas putida using engineered
modular plasmids and color proteins (fluorescent and chromo- proteins)
Ionic liquid based extraction and stability of biomolecules
Antenna size reduction as a strategy to increase biomass productivity: A great potential not yet realized.
Catalytic properties of laccase-like multicopper oxidases from Aspergillus niger
Distinct Roles of Ger-receptors in Heat Activation of Bacillus subtilis Spore Germination
Selection of resins for purification of antioxidants from food waste streams
A fast, sensitive and easy colorimetric assay for chitinase and cellulase activity detection
Selection of an anti-modified citrulline antibody by phage display
Chemometric analysis of soy protein hydrolysates used in animal cell culture for IgG production – An untargeted
metabolomics approach
Storage of mammalian cells at 4°C with ROKEPIE-S01®

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