TOC (PDF) - Circulation

Circulation
Volume 131 ◼ Number 1
January 6, 2015
Editorial Board. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Clinical Summaries. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Editorials
Physiologic Severity of Diffuse Coronary Artery Disease: Hidden High Risk
K. Lance Gould, MD; Nils P. Johnson, MD, MS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Regional Differences in Heart Failure With Preserved Ejection Fraction Trials: When Nephrology Meets
Cardiology but East Does Not Meet West
Patrick Rossignol, MD, PhD; Faiez Zannad, MD, PhD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Prospective Comparison of ARNi With ACE-I to Determine Impact on Global Mortality and Morbidity in
Heart Failure (PARADIGM-HF): Paragon of a Study or Further Investigation Paramount?
Henry Krum, MBBS, PhD, FRACP, FESC, FCSANZ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Long-Term Secondary Prevention After High-Risk Stenting: A Good Drug for a Bad Stent
Jean-Philippe Collet, MD, PhD; Johanne Silvain, MD, PhD; Gilles Montalescot, MD, PhD . . . . . . . . . . . . . . . . . . . . . . 13
Reinvestment in Government-Funded Research: A Great Way to Share
Paul D. Sorlie, PhD; Phyliss D. Sholinsky, MSPH; Michael S. Lauer, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Original Articles
Coronary Heart Disease
Global Coronary Flow Reserve Is Associated With Adverse Cardiovascular Events Independently of Luminal
Angiographic Severity and Modifies the Effect of Early Revascularization
Viviany R. Taqueti, MD, MPH; Rory Hachamovitch, MD, MS; Venkatesh L. Murthy, MD, PhD;
Masanao Naya, MD, PhD; Courtney R. Foster, MS; Jon Hainer, BS; Sharmila Dorbala, MD, MPH;
Ron Blankstein, MD; Marcelo F. Di Carli, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Health Services and Outcomes Research
A Randomized Trial of Social Media From Circulation
Caroline S. Fox, MD, MPH; Marc A. Bonaca, MD, MPH; John J. Ryan, MD; Joseph M. Massaro, PhD;
Karen Barry, MS; Joseph Loscalzo, MD, PhD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Heart Failure
Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure
With an Aldosterone Antagonist (TOPCAT) Trial
Marc A. Pfeffer, MD, PhD; Brian Claggett, PhD; Susan F. Assmann, PhD; Robin Boineau, MD; Inder S. Anand, MD;
Nadine Clausell, MD, PhD; Akshay S. Desai, MD, MPH; Rafael Diaz, MD; Jerome L. Fleg, MD; Ivan Gordeev, MD;
John F. Heitner, MD; Eldrin F. Lewis, MD, MPH; Eileen O’Meara, MD; Jean-Lucien Rouleau, MD;
Jeffrey L. Probstfield, MD; Tamaz Shaburishvili, MD, PhD; Sanjiv J. Shah, MD; Scott D. Solomon, MD;
Nancy K. Sweitzer, MD, PhD; Sonja M. McKinlay, PhD; Bertram Pitt, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
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International Geographic Variation in Event Rates in Trials of Heart Failure With Preserved and Reduced
Ejection Fraction
Søren L. Kristensen, MD, PhD; Lars Køber, MD, DMSc; Pardeep S. Jhund, MBChB, PhD; Scott D. Solomon, MD;
John Kjekshus, MD; Robert S. McKelvie, MD, PhD; Michael R. Zile, MD; Christopher B. Granger, MD;
John Wikstrand, MD; Michel Komajda, MD; Peter E. Carson, MD; Marc A. Pfeffer, MD, PhD;
Karl Swedberg, MD, PhD; Hans Wedel, PhD; Salim Yusuf, MD, DPhil; John J. V. McMurray, MD . . . . . . . . . . . . . . . . . 43
Angiotensin Receptor Neprilysin Inhibition Compared With Enalapril on the Risk of Clinical Progression in
Surviving Patients With Heart Failure
Milton Packer, MD; John J.V. McMurray, MD; Akshay S. Desai, MD, MPH; Jianjian Gong, PhD;
Martin P. Lefkowitz, MD; Adel R. Rizkala, PharmD; Jean L. Rouleau, MD; Victor C. Shi, MD; Scott D. Solomon, MD;
Karl Swedberg, MD, PhD; Michael Zile, MD; Karl Andersen, MD, PhD; Juan Luis Arango, MD;
J. Malcolm Arnold, MD; Jan Bĕlohlávek, MD, PhD; Michael Böhm, MD; Sergey Boytsov, MD;
Lesley J. Burgess, MBBCh, PhD; Walter Cabrera, MD; Carlos Calvo, MD; Chen-Huan Chen, MD;
Andrej Dukat, MD; Yan Carlos Duarte, MD; Andrejs Erglis, MD, PhD; Michael Fu, MD; Efrain Gomez, MD;
Angel Gonzàlez-Medina, MD; Albert A. Hagège, MD, PhD; Jun Huang, MD; Tzvetana Katova, PhD;
Songsak Kiatchoosakun, MD; Kee-Sik Kim, MD, PhD; Ömer Kozan, Prof Dr; Edmundo Bayram Llamas, MD;
Felipe Martinez, MD; Bela Merkely, MD; Iván Mendoza, MD; Arend Mosterd, MD, PhD;
Marta Negrusz-Kawecka, MD, PhD; Keijo Peuhkurinen, MD; Felix J.A. Ramires, MD, PhD;
Jens Refsgaard, MD, PhD; Arvo Rosenthal, MD, PhD; Michele Senni, MD; Antonio S. Sibulo Jr, MD;
José Silva-Cardoso, MD, PhD; Iain B. Squire, MD; Randall C. Starling, MD, MPH; John R. Teerlink, MD;
Johan Vanhaecke, MD, PhD; Dragos Vinereanu, MD, PhD; Raymond Ching-Chiew Wong, MBBS;
on behalf of the PARADIGM-HF Investigators and Coordinators CME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54
Interventional Cardiology
Prasugrel Plus Aspirin Beyond 12 Months Is Associated With Improved Outcomes After Taxus Liberté
Paclitaxel-Eluting Coronary Stent Placement
Kirk N. Garratt, MD, MSc; W. Douglas Weaver, MD; Ronald G. Jenkins, MD; Thomas K. Pow, MD;
Laura Mauri, MD, MSc; Dean J. Kereiakes, MD; Kenneth J. Winters, MD; Thomas Christen, MD, PhD;
Dominic J. Allocco, MD, MSc; David P. Lee, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
Long-Term Efficacy and Safety of Biodegradable-Polymer Biolimus-Eluting Stents: Main Results of the Basel
Stent Kosten-Effektivitäts Trial–PROspective Validation Examination II (BASKET-PROVE II), A Randomized,
Controlled Noninferiority 2-Year Outcome Trial
Christoph Kaiser, MD; Soeren Galatius, MD; Raban Jeger, MD; Nicole Gilgen, MD; Jan Skov Jensen, MD;
Christoph Naber, MD; Hannes Alber, MD; Maria Wanitschek, MD; Franz Eberli, MD; David J. Kurz, MD;
Giovanni Pedrazzini, MD; Tiziano Moccetti, MD; Hans Rickli, MD; Daniel Weilenmann, MD;
André Vuillomenet, MD; Martin Steiner, MD; Stefanie Von Felten, PhD; Deborah R. Vogt, PhD;
Kim Wadt Hansen, MD; Peter Rickenbacher, MD; David Conen, MD; Christian Müller, MD; Peter Buser, MD;
Andreas Hoffmann, MD; Matthias Pfisterer, MD; for the BASKET-PROVE II Study group . . . . . . . . . . . . . . . . . . . . . . . . 74
Vascular Medicine
Edoxaban Effects on Bleeding Following Punch Biopsy and Reversal by a 4-Factor Prothrombin Complex
Concentrate
Hamim Zahir, PhD; Karen S. Brown, PhD; Alexander G. Vandell, PharmD, PhD; Madhuri Desai, MS;
Jen-Fue Maa, PhD; Victor Dishy, MD; Barbara Lomeli, MD; Annette Feussner; Wenqin Feng, PhD; Ling He, PhD;
Michael A. Grosso, MD; Hans J. Lanz, MD; Elliott M. Antman, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82
Challenges and Opportunities in Pediatric Heart Failure and Transplantation
Changing Indications for Pediatric Heart Transplantation: Complex Congenital Heart Disease
Daphne T. Hsu, MD; Jacqueline M. Lamour, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Special Report
American Heart Association Cardiovascular Genome-Phenome Study: Foundational Basis and Program
Ivor Benjamin, MD; Nancy Brown; Gregory Burke, MD, MSc; Adolfo Correa, MD, MPH, PhD;
Steven R. Houser, PhD; Daniel W. Jones, MD; Joseph Loscalzo, MD, PhD; Ramachandran S. Vasan, MD;
Gayle R. Whitman, PhD, RN
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
ECG Challenge
ECG Challenge: January 6, 2015 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113
Images in Cardiovascular Medicine
Diagnosis and Resolution of Löeffler Endocarditis Secondary to Eosinphilic Granulomatosis With Polyangiitis
Demonstrated by Cardiac Magnetic Resonance–T2 Mapping
Ross T. Campbell, BSc, MBChB; Pardeep S. Jhund, BSc, MBChB, MSc, PhD; Jonathan R. Dalzell, MD;
Jane Cannon, MBChB; Ify Mordi, MBChB; Piotr Sonecki, MD; Nikolaos Tzemos, BSc, MD . . . . . . . . . . . . . . . . . . . . . 114
Transdiaphragmatic Rupture of Hepatic Abscess Producing Purulent Pericarditis and Pericardial Tamponade
Gautam Reddy, MD; Arka Chatterjee, MD; Brigitta C. Brott, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e1
Cardiology Patient Page
Spontaneous Coronary Artery Dissection (SCAD)
Jacqueline Saw, MD; Tara Sedlak, MD; Santhi K. Ganesh, MD; Saul Isserow, MD; G.B. John Mancini, MD . . . . . . . . . e3
Correspondence
Letter by Dai et al Regarding Article, “ST-Elevation Myocardial Infarction Diagnosed After Hospital
Admission”
Xuming Dai, MD, PhD; Prashant Kaul, MD; George A. Stouffer, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e6
Response to Letter Regarding Article, “ST-Elevation Myocardial Infarction Diagnosed After Hospital
Admission”
Ross F. Garberich, MS; Jay H. Traverse, MD; Michael T. Claussen, BS; Gabriel Rodriguez, BS; Anil K. Poulose, MD;
Ivan J. Chavez, MD; Stephanie Rutten-Ramos, DVM, PhD; David A. Hildebrandt, RN; Timothy D. Henry, MD . . . . . . . e7
Letter by Khan and Moukarbel Regarding Article, “Risk for Myocardial Infarction and Stroke After
Community-Acquired Bacteremia: A 20-Year Population-Based Cohort Study”
Abdur Rahman Khan, MD; George V. Moukarbel, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e8
Response to Letter Regarding Article, “Risk for Myocardial Infarction and Stroke After
Community-Acquired Bacteremia: A 20-Year Population-Based Cohort Study”
Michael Dalager-Pedersen, MD, PhD; Mette Søgaard, DVM, PhD; Henrik Carl Schønheyder, MD, DMSc;
Henrik Nielsen, MD, DMSc; Reimar Wernich Thomsen, MD, PhD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e9
Correction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e10

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