Dengue Surveillance and Response in Thailand Dr.Sopon Iamsirithaworn, MD, MPH, PhD Office of Disease Prevention and Control 1, Department of Disease Control, Ministry of Public Health, Thailand 1 April 2014 Outline of Presentation Case-based surveillance for dengue (DF/DHF/DSS) Epidemiology of dengue in Thailand Dengue responses in Thailand, 2013 2 Source of Dengue Surveillance Data Case-based surveillance and reported as DF/DHF/DSS District Hospitals Provincial hospitals ผลลัพธ์ ของการติดเชือไวรัสเด็งกี (Dengue infection) มีอาการป่ วย 10% ไม่ มอี าการ 90% Expanded dengue Dengue syndrome * Undifferential Dengue fever haemorrheagic Fever syndrome(DF4%) fever (DHF1%) (viral syndrome) CNS/Encephalitis (Fever 5%) Plasma leakage - Hepatitis/FHF Classical With - Myocarditis unusual - ARF haemorrhage No shock With shock (DSS) - Eye involvement - IAHS - etc. * Severe dengue unusual manifestation isolated organopathy ผลลัพธ์ของการติดเชื้อไวรัสเด็งกี่ DSS DHF Dengue Fever Undifferentiated Fever No Symptom Dengue Incidence Rate in Thailand, 1958-2013 Rate per 100,000 pop 350 2013 2nd largest outbreak (235/100,000) 1987 Largest outbreak (325/100,000) 300 250 200 150 100 50 1958 1st Outbreak 1978 Every district 0 1958 1963 1968 1973 1978 1983 1988 1993 1998 2003 2008 2013 Year Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Regional dengue surveillance WHO: Dengue Situation Updates as of 14 March 2014. Accessed at www.wpro.who.int/emerging_diseases/DengueSituationUpdates/en/index.html Health Security and Emergencies 7 Regional dengue surveillance WHO: Dengue Situation Updates as of 14 March 2014. Accessed at www.wpro.who.int/emerging_diseases/DengueSituationUpdates/en/index.html Health Security and Emergencies 8 Regional dengue surveillance WHO: Dengue Situation Updates as of 14 March 2014. Accessed at www.wpro.who.int/emerging_diseases/DengueSituationUpdates/en/index.html Health Security and Emergencies 9 Regional dengue surveillance WHO: Dengue Situation Updates as of 14 March 2014. Accessed at www.wpro.who.int/emerging_diseases/DengueSituationUpdates/en/index.html Health Security and Emergencies 10 Global Dengue Situation • Incidence of dengue has increased dramatically around the world in recent decades • Over 2.5 billion people (over 40% of the world's population) are at risk • WHO currently estimates 50–100 million dengue infections worldwide every year • 2-5 yr epidemic cycles Health Security and Emergencies 11 DF/DHF/DSS Situation in Thailand, 2013 No. of cases: Morbidity rate: pop No. of deaths: CFR: 150,934 235 per 100,000 133 0.09% Source: Bureau of Epidemiology, MoPH, Thailand DF/DHF/DSS Situation in Thailand, 2013 Thailand Bangkok Source: Bureau of Epidemiology, MoPH, Thailand Number of Reported DF/DHF/DSS by Month, Thailand January 2013 – February 2014 No. of cases 2013 2014 Week of disease onset Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Updated situation of DF/DHF/DSS, Thailand 1 January 2010 – 25 March 2014 Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Dengue Morbidity Rates and Case Fatality Rates, Thailand, 1958-2013 Morbidity rate (per 100,000 pop) CFR (%) Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Percentage of reported DF/DHF/DSS cases, Thailand, 2013 2.0% 55.40% 42.60% DF DHF DSS Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Seasonal Trend of Dengue in Thailand Fig. 4 Reported Cases of D.H.F,Total(26,27,66) by Month, Thailand, 2003 - 2007 June - Aug N u m b er o f C ases 14000 12000 10000 8000 6000 4000 2000 0 Jan Feb Mar 2003 Apr May 2004 Jun Jul 2005 Aug Sep 2006 Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Oct Nov 2007 Dec Incidence rate of DF/DHF/DSS per 100,000 pop by age group, Thailand, 2013 Rate/100,000 pop Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Percentages of Dengue in Adults and Children, Thailand Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Percentage of Reported DF/DHF/DSS Cases by Gender, Thailand, Jan-Aug 2013 Source: Bureau of Epidemiology, Ministry of Public Health, Thailand Dengue Serotypes Circulation in Thailand, 1972-2013 %Serotype Rate per 100,000 pop 100% 350 300 75% 250 200 50% 150 100 25% DEN-1 DEN-2 DEN-3 Source : 1. National Surveillance System, Bureau of Epidemiology, MOPH, Thailand 2. Serotype data: Department of Medical Sciences, MOPH, Thailand DEN-4 CR 2013 2011 2012 2009 2010 2007 2008 2006 2004 2005 2002 2003 2000 2001 1999 1997 1998 1995 1996 1993 1994 1992 1990 1991 1987 1989 1986 1984 1985 1982 1983 1980 1981 1979 1977 1978 1975 1976 1973 1974 0% 1972 50 0 Dengue control strategies in Thailand ผลการศึกษา Dengue responses in Thailand, 2013 • National agenda – Public health crisis – Emergency operation center • Multi-sectoral collaboration – Government, private, local administration, public sectors – Intensive risk communication • Strengthening dengue surveillance • Improving clinical practice guidelines for dengue treatment in adult patients Minister of Health and Public Education Larval survey and breeding source reduction by community participation Thank you for your attention
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