Products Guide Blending food technology with life science for clearly better products. www.clearh2o.com ClearH2O ’s tyvek packaged products are the only hydration and nutrition products that are Sterile Inside and Out. Our rodent and herbivore products are gamma irradiated, packaged in tyvek medical packaging. The result is ease of use; no need to sterilize individual pouches or cups, reducing ® the use of chemical sterilants, saving on labor cost and improving on efficiency. Our knowledge of taste preferences promotes consumption, enhancing wellness and survival for your animals. ClearH2O products help you advance your research and results. ® HydroGel is the #1 choice of breeders worldwide for hydrating research animals in transit, DietGel products are the #1 soft dietary supplement for compromised or special needs animals, MediGel products are fast becoming the preferred medication delivery method, while LabGel and FiberBites continue to offer unique and effective enrichment for non human primates. ® ® ® ® ® ClearH2O is a Maine-based technology company meeting the needs of leading industry researchers and breeders. A strategic partnership with food and nutritional scientists allows us to provide cost-effective solutions to address unmet market demands, while saving time and labor. ClearH2O products are always consistent, eliminating nutrition and hydration variables in research. ® ® ClearH2O products are manufactured under stringent quality standards. Our commitment to quality is supported by an FDA approved HAACCP facility that is inspected by Silliker, NSF Cook & Thurber and other third-party inspectors. All HydroGel , DietGel , MediGel , LabGel and FiberBites products are tested and receive a certificate of analysis. ® ® ® ® ® ® Products Guide Contents Quick Reference Guide 4 HydroGel 6 DietGel 8 ™ ® MediGel 12 LabGel 18 ™ ® FiberBites ® 20 www.clearh2o.com 3 Quick Reference Guide 4 PRODUCT PRIMARY ANIMAL APPLICATIONS HydroGel® Rodents Guinea Pigs Hydrates animals in transit. Water supplement for compromised, recovering or weaning animals. Transitions animals to automated watering systems. Emergency source of potable water. DietGel® Recovery Rodents Aides recovery for post surgical, weak or impaired rodents. DietGel® 76A Rodents Replaces mash diets for post surgical, breeding and compromised rodents. DietGel® Boost Rodents Provides energy for weanlings, post surgical, debilitated and aging animals. DietGel® Criticare Rabbits Guinea Pigs Timothy Hay for herbivores unwilling to eat their normal diet due to illness, surgery or malnutrition. MediGel™ FBZ Rodents 150 ppm Fenbendazole for treatment against pinworms. MediGel™ Sucralose Rodents Thermoreversable water gel for delivering medication. LabGel® Banana Non-Human Primates Provides enrichment, hydration and a medication delivery vehicle. LabGel® Rasberry Non-Human Primates Provides enrichment, hydration and a medication delivery vehicle. FiberBites® Non-Human Primates Provides enrichment, treats non-specific diarrhea and nourishes beneficial bacteria, promoting a healthy digestive tract. PROCESS LEVEL KEY INGEDIENTS SHELF LIFE STORAGE Irradiated 98% purified water 18 Months Room temp. Irradiated Purified Water, Corn Sugar, Electrolyte Mix 12 Months Room temp. Irradiated Purified Water, Molasses, Calcium Caseinate, AIN Mineral & Vitamin Mix 12 Months Room temp. Irradiated Vegetable Oil, Pumpkin, Molasses, Purified Water 12 Months Room temp. Irradiated Purified Water, Pineapple Juice, Pumpkin, Timothy Hay, Mineral & Vitamin Mix 12 Months Room temp. Irradiated Purified Water, Electrolyte Mix, Blue Color 12 Months Room temp. Irradiated Purified Water, Electrolyte Mix, Sucralose 18 Months Room temp. Ultra Pasteurized 92 % Purified Water, Banana, Electrolyte Mix 18 Months Room temp. Ultra Pasteurized 92% Purified Water, Raspberry Juice, Electrolyte Mix 18 Months Room temp. Human Grade Chicory Root Fiber (inulin), Purified Water, Natural Flavors 18 Months Room temp. www.clearh2o.com 5 HydroGel ® Non-Wetting Water Gel for Animal Hydration HydroGel® is a non-wetting, sterile water gel for animal hydration. 98% pure water. The industry standard for hydration during transportation. Delivering Solutions • • • • Suitable for short or long transit shipping times Supplement for compromised, recovering or weaning animals Useful in transitioning animals to automated watering systems Emergency water source and alternative to water bottles Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials ® 6 HydroGel ® Nutritional Information per 100g Calories Protein Carbohydrates Dietary Fiber Sugars Fat (total) Calcium Phosphorus Potassium Sodium 6.3kcal 0 1.5g 1.4g 0 0 3.6mg 22.6mg 55.4mg 38.0mg Ingredients Purified Water (98%), Hydrocolloids, Food Acid, Sodium Benzoate, Potassium Sorbate Shelf Life Ordering Information HydroGel® - 70-01-5022 2 oz cup (56g) 96 cups per box Barrier packed HydroGel® - 70-01-1062 6 oz pouch (170g) 70 pouches per box Barrier packed HydroGel® - 70-01-1082 8 oz pouch (226g) 55 pouches per box Barrier packed 18 month shelf life. Does not require refrigeration or special handling. www.clearh2o.com 7 DietGel Recovery ® Purified Soft Diet for Laboratory Rodents DietGel® Recovery is a nutrient fortified water gel that aids in the recovery of post surgical, weak or impaired rodents. Proven to increase survival rates in compromised animals. Formulated from purified ingredients that provide 60% water, calories and electrolytes. Delivering Solutions • • • • Increases post-surgical survival rate Soft formulation promotes consumption Designed to retain moisture without skinning over Reduces time and labor Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Purified ingredients exclude phytoestrogens and nitrosamines • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials ® 8 DietGel® Recovery Improves Post Surgical Weight in Mice Post Surgical Weight Recovery of Ovariectomized C57BL/6J Females 20.5 Weight (grams) 20 19.5 19 18.5 18 17.5 17 0 1 2 3 4 5 6 7 8 Days post-surgery DietGel Recovery Water Figure 1. Twenty, 8-week-old C57BL/6J females were ovariectomized and upon recovery from anesthesia divided into two equal groups. Pre and post operatively all mice were provided a standard 6% fat rodent diet in hard pellet form and acidified water ad libitum. In addition to the standard diet, Group #2 was provided DietGel Recovery ad libitum post operatively for 8 days. Mice were housed 10 per cage. Weights and physical appearance were recorded daily. Results demonstrate that mice supplemented with DietGel Recovery lost less body weight postoperatively and attained preoperative body weight within 5 days. DietGel® Recovery Acknowledgments to The Jackson Laboratory for study design, data and support. Nutritional Information per 100g 2 oz Cup 6 oz Pouch Calories 4-4-9 149.6 kcal 153.4 kcal Protein 0.6 g 0.7 g Carbohydrates - total 32.7 g 33.6 g Sugars 31.0 g 31.1 g Dietary Fiber 0.6 g 1.4 g Fat – total 1.8 g 1.8 g Saturated Fat 0.2 g 0.2 g Trans Fatty Acids 0 0 Cholesterol 0.3 mg 0.3 mg Moisture 63-65 % 62-64 % Sodium 54.4 mg 63.4 mg Potassium 94.0 mg 96.1 mg Calcium 23.7 mg 37.2 mg Chloride 105.2 mg 105.4 mg Ingredients Purified Water, Corn syrup, Hydrocolloids, Vegetable Oil, Calcium Caseinate, Electrolyte Mix, Food Acid, Mineral Mix Shelf Life 12 month shelf life. Does not require refrigeration or special handling. Ordering Information DietGel® Recovery 72-01-5022 2 oz cup (56g) 96 cups per box Barrier packed DietGel® Recovery 72-01-1062 6 oz pouch (170g) 70 pouches per box Barrier packed www.clearh2o.com 9 DietGel 76A ® Purified Soft Diet for Laboratory Rodents DietGel® 76A is a nutritionally complete soft diet, combining hydration and nutrition in a single serving. Formulated with purified ingredients, modeled on the 76A maintenance diet formulation. It is flavor enhanced resulting in increased consumption. Delivering Solutions • • • • Superior alternative to mash diets Designed to retain moisture, without skinning over Reduces time and labor Reduces potential for contamination Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Purified ingredients exclude phytoestrogens and nitrosamines • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials ® 10 DietGel® 76A Improves Post Surgical Weight in Mice Post Surgical Weight Recovery in C57BL/6J Ovariectomized Females 20.5 Weight (grams) 20 19.5 19 18.5 18 17.5 17 0 1 2 3 4 5 6 7 8 Days post-surgery ® DietGel 76A Water Figure 1. Twenty, 8-week-old C57BL/6J females were ovariectomized and upon recovery from anesthesia divided into two equal groups. Pre and post operatively all mice were provided a standard 6% fat rodent diet in hard pellet form and acidified water ad libitum. In addition to the standard diet, Group #2 was provided DietGel 76A ad libitum, post operatively for 8 days. Mice were housed 10 per cage. Weights and physical appearance were recorded daily. Results demonstrate that mice supplemented with DietGel Recovery lost less body weight postoperatively and attained preoperative body weight within 5 days. DietGel® 76A Acknowledgments to The Jackson Laboratory for study design, data and support. Nutritional Information per 100g Calories Protein Carbohydrates - total Sugars Dietary Fiber Fat – total Saturated Fat Trans Fatty Acids Cholesterol Moisture Sodium Potassium Calcium Phosphorus 99.8kcal 4.7g 17.9g 12.9g 1.4g 1.5g 0.1g 0 1.9mg 73.4% Vitamin A Vitamin B1 Vitamin B2 Vitamin B3 Vitamin B6 Vitamin B12 Vitamin D Folate Pantothenic Acid 159.9IU 0.2mg 0.2mg 1.2mg 0.3mg 999.4mcg 39.9IU 79.9mcg 0.7mg 40.6mg 273.4mg 233.5mg 262.1mg Ingredients Purified water, molasses, corn syrup, Calcium Caseinate, Vegetabl Oil, Food Acids, AIN Mineral Mix, Hydrocolloids, Cellulose, AIN Vitamin Mix Shelf Life 12 month shelf life. Does not require refrigeration or special handling. Ordering Information DietGel® 76A 72-03-5022 2 oz cup (56g) 96 cups per box Barrier packed www.clearh2o.com 11 DietGel Boost ® Purified High Calorie Dietary Supplement for Laboratory Rodents DietGel® Boost is a high-calorie supplement that provides energy for weanlings, post surgical, debilitated and aging animals. Delivering Solutions • • • • Provides supplemental caloric and nutritional intake Great taste promotes consumption Provides extra energy to aid in recovery Easily digested soft paste, suitable for oral gavage Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • FDA approved materials ® 12 DietGel® Boost Nutritional Information per 100g Shelf Life Calories 352 Protein 0.4g Carbohydrates - total 23.0g Sugars 13.3g Dietary Fiber 1.3g Fat - total 28.3g Saturated Fat 6.2g Trans Fatty Acids 0 Cholesterol 0 Moisture 45-50% Vitamin A 5910.9IU Vitamin C 201.0mg Calcium 53.9mg Phosphorus 67.2mg Potassium 379.7mg Sodium 13.6mg 12 month shelf life. Does not require refrigeration or special handling. Product separation is natural, stir well to blend. (Similar to all natural peanut butter.) Storage Storage at 35° F (2°C) reduces product separation. Ingredients Pumpkin, Vegetable Oils, Molasses, Purified Water, Corn Starch, Vitamin Mix, Sunflower Lecithin, Food Acids, Hydrocolloids Ordering Information DietGel® Boost 72-04-5022 2 oz cup (56g) 96 cups per box Barrier packed www.clearh2o.com 13 DietGel Criticare ® Dietary Supplement with Timothy Hay for Herbivores DietGel® Criticare, formulated with Timothy Hay, is a nutritional supplement for herbivores that are unwillig to eat their normal diet, due to illness, surgery or malnutrition. Delivering Solutions • Soft flavorful formulation promotes consumption • Ensures proper gut physiology and digestion, and aides recovery • Ready to use - no mixing required Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot ® 14 DietGel® Criticare Nutritional Information per 100g Ingredients Calories 78.0kcal Protein 5.3g Carbohydrates - total 18.5g Sugars 9.0g Dietary Fiber 7.7g Fat – total 1.0g Saturated Fat 0.1g Trans Fatty Acids 0 Cholesterol 0 Moisture 70-72% Vitamin A 669.1IU Vitamin B1 0.3mg Vitamin B2 0.3mg Vitamin B3 1.5mg Vitamin B12 1250.0mcg Vitamin C 21.3mg Vitamin D 50.0IU Calcium 263.4mg Chloride 24.1mg Chromium 14.2mcg Copper 0.1mg Iron 3.2mg Magnesium 14.2mg Phosphorous 136.9mg Potassium 238.3mg Sodium 67.3mg Zinc 0.6mg Purified Water, Fruit Juice Concentrates, Cellulose, Sunflower Flour, Soy Protein Isolate, Pumpkin, Timothy Hay, Food Acids, Hydrocolloids, Mineral Mix, Vitamin Mix, Sunflower Oil Shelf Life 12 month shelf life. Does not require refrigeration or special handling. Ordering Information DietGel® Criticare 72-05-5042 4 oz cup (112g) 72 cups per box Barrier packed www.clearh2o.com 15 MediGel FBZ ® Non-wetting Water Gel for Fenbendazole Delivery MediGel® Fenbendazole is a ready to use hydration gel with 150 ppm Fenbendazole for the treatment of pinworm. Delivering Solutions • • • • Broad-spectrum anthelmintic with aldulticidal, larvicidal and ovididal action, effective against pinworms Flavor masking for ease of medication delivery For use in quarantine and as prophylaxis 98% purified water Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials ® 16 MediGel FBZ ® Nutritional Information per 100g Fenbendazole Calories Moisture Protein Carbohydrates Dietary Fiber Sugars (total) Fat (total) Saturated Fat Calcium Chloride Phosphorus Potassium Sodium 150ppm 6.0kcal 98.0g 0 1.4g 1.3g 0 0 0 3.4mg 0.9g 26.3mg 57.8mg 24.3mg Ordering Information MediGel® FBZ 74-01-5042 4 oz cup (112g) 72 cups per box Barrier packed Ingredients Purified Water, Hydrocolloids, Electrolyte Mix, Food Acid, Sucralose, Fenbendazole, FD&C Blue #1 Shelf Life 12 month shelf life. Does not require refrigeration or special handling. www.clearh2o.com 17 MediGel Sucralose ® Non-wetting Thermo Reversible Water Gel for Medication Delivery MediGel® Sucralose is a flavored, low calorie water gel, designed to administer medication to your research animal. Delivering Solutions • • • • • Thermoreversible gel eases medication delivery 98% pure, sterile water Low calorie sweetner masks medicinal taste Enhanced flexibility through in-house preparation and dosing No order lead time or minimum quantity requirement Delivering Quality • Sterile inside and out • Tyvek medical packaging • Gamma irradiated • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials ® 18 MediGel Sucralose ® Nutritional Information per 100g Calories Moisture Protein Carbohydrates Dietary Fiber Sugars (total) Fat (total) Saturated Fat Calcium Chloride Phosphorus Potassium Sodium 3.1kcal 98.8g 0 0.7g 0.6g 0 0 0 1.8mg 0.9mg 24.4mg 41.4mg 20.1mg Ordering Information MediGel® Sucralose 74-02-5022 2 oz cup (56g) 96 cups per box Barrier packed Ingredients Purified Water, Hydrocolloids, Natural Flavor, Electrolyte Mix, Food Acid, Sucralose Shelf Life 18 month shelf life. Does not require refrigeration or special handling. www.clearh2o.com 19 LabGel ® Naturally Flavored Gels Providing Enrichment, Hydration, and Medication Delivery LabGel® is a non-wetting naturally flavored gel, designed to provide enrichment and hydration. It is a an excellent vehicle for medication delivery, for your non human primates and other research animals. Flavor enhanced to promote acceptance and consumption. Delivering Solutions • Thermo-reversible gel supports various applications: - Use with enrichment devices - Delivery and flavor masking of oral medications • Provides up to 93% water for efficient hydration • Available in a No Sugar Added formulation, for calorie restricted diets Delivering Quality • Purified ingredients • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • Individually coded with lot and date of expiration • FDA approved materials 20 LabGel® (No Sugar Added) Nutritional Information per 100g Banana Calories 24.6kcal Protein 0.2g Carbohydrates (total) 5.6g Sugars (total) 3.9g Dietary Fiber 1.5g Fat (total) 0.2g Saturated Fat 0.1g Trans Fatty Acids 0 Cholesterol 0 Moisture 92-94% Sodium 24.2g Potassium 111.2g Calcium 3.8g Chloride 0.7g Phosphorus 35.4g Raspberry 25.4kcal 0.1g 6.2g 3.8g 1.1g 0 0 0 0 89-91% 24.3g 133.2g 5.2g 0.8g 1.2g Ordering Information LabGel® Banana No Sugar Added 71-02-1081 8 oz pouch (226 g) 55 pouches per box LabGel® Raspberry No Sugar Added 71-03-1081 8 oz pouch (226 g) 55 pouches per box Ingredients Purified Water, Fruit (Banana / Raspberry Juice Concentrate), Hydrocolloids, Natural Flavor, Electrolyte Mix, Food Acid, Sucralose Shelf Life 18 month shelf life. Does not require refrigeration or special handling. www.clearh2o.com 21 FiberBites ® Fiber Fortified Nutraceutical for Non-Human Primates Fiberbites® acts as a prebiotic to nourish beneficial bacteria, promoting a healthy digestive tract. Made with a natural source of inulin. Delivering Solutions • • • • • • • High Level of fiber Natural flavors promote acceptance Convenient and easy to administer No mixing or dissolving necessary Low in calories Cost effective Available in 10# value pack Delivering Quality • Complies with quality standards as tested by an independent laboratory • Certificate of analysis by manufactured lot • FDA approved materials 22 FiberBites® Recommended Dosage Shelf Life Fiber: 1-2 g/kg/day to supplement the fiber content in the diet. Each FiberBite contains 2 grams of fiber. 18 month shelf life. Does not require refrigeration or special handling. Storage Nutritional Information per piece (4 grams) Each piece contains: Calories Protein Carbohydrates Dietary Fiber Sugars (total) Fat (total) Calcium Phosphorus Potassium Sodium Best if stored between 55° and 65°F (13° and 18° C) 7.5kcal 0 3.0g 2.0g 0.4g 0 0 0 0 0.8g Ingredients Chicory Root Fiber (Inulin), Water, Hydrocolloid, Food Acids, Vegetable Color, Natural Flavors, Vegetable Oil, Beeswax Ordering Information FiberBites® 73-01-2101 4 gram drop (2.0 g fiber per drop) 1,135 drops per 10 lb case www.clearh2o.com 23 Blending food technology with life science for clearly better products. Company Information ClearH2O , is committed to providing hydration, nutrition and enrichment products that improve the overall welfare of research animals. Our in-house scientists understand that the health and welfare of lab animals is critical to your research. ClearH2O products provide convenient, high-quality, consistent nutrition and hydration to promote animal wellness. Made at our FDA approved facility, ClearH2O products are prepared with purified ingredients and enhanced flavor to improve consumption. ® ® ® www.clearh2o.com 1-888-493-7645 117 Preble Street Portland, Maine 04101 1-888-HYDROGL (1-888-493-7645) Fax: 1-207-774-3449
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