ISOBC NEWSLETTER Volume 9, Number 1 March, 2014 Volume 9, Number 1 Iran Society of Biophysical Chemistry 2014 ISOBC NEWSLETTER 2014 Volume 9, Number 1 Scientific Biography of Carlos Warnick (Nick) Pace Prepared by: A.Poursoleiman, IBB, University of Tehran Carlos Warnick (Nick) Pace was born on February 22, 1940 in Salt Lake City, Utah in the United States. He received his B.S. in Chemistry in 1962 from University of Utah and his Ph.D. in Biochemistry from Duke University in 1966. For his Ph.D. research, Pace worked with Journal of Biological Chemistry (JBC) Classic author Charles Tanford, who was interested in protein denaturation and solubility in various solutions. After doing a postdoctoral fellowship from 1966 to 1968 with Gordon Hammes at Cornell, he joined to Department of Biochemistry and Biophysics at Texas A & M in 1968. In 1982 he took a Sabbatical at the MRC Centre in Cambridge England working with Tom Creighton and Alan Barrett. In 1992 he was a Visiting Professor at Osaka University at the Institute for Protein Research. As an independent researcher, Pace used the ideas and techniques he learned in Tanford’s laboratory to study protein folding and denaturation. The JBC paper described a new method for estimating protein stability called the linear extrapolation method. The method is the most widely used for measuring protein stability, and the paper has been cited more than 370 times. Pace and others used optical rotation measurements to follow the unfolding of proteins in urea and guanidine hydrochloride. By analyzing the proteins’ denaturation curves via above procedure, they were able to make linear plots of the free energy of unfolding (G) versus denaturant concentrations. The plot’s intercept gave a measure of the protein’s stability whereas the slope gave an “m value” that measured how strongly G depended on urea concentration. Pace’s follow‐up paper on m values is the third most cited paper in the history of Protein Science with about 800 citations. Today, Pace remains at Texas A&M where he is a distinguished professor at the Health Science Center. He has received many awards and honors for his contributions to science. 2014 ISOBC NEWSLETTER Volume 9, Number 1 News The 1st Iranian Symposium on “Biomimetic Science and Technology” The 1st Iranian Symposium on “Biomimetic Science and Technology” hosted by the Institute of Biochemistry and Biophysics at the University of Tehran was held on February 18th, 2014. In this one‐day conference the scientists from the main Iranian Universities presented their recent activities on the field of Biomimitics. This conference organized by Iran society of Biophysical Chemistry and Iran Peptide Society. 2014 ISOBC NEWSLETTER Volume 9, Number 1 Here we have shortly presented the information on the symposium schedule. Session 1 Keynote Speaker Welcome ceremony Ali Akbar Moosavi‐Movahedi 9:00‐9:25 Peyman Salehi 9:25‐9:50 Freidoun Mahboudi 9:50‐10:15 Abbas Shafiee 10:15‐10:30 Session 2 Tea break 10:30‐10:55 Jawad A. Salehi 10:55‐1:20 Soroush Sardari Biological communications systems and processors Drug design based on biomimicry 11:20‐1:45 Kambiz Gilani Peptidomics 11:45‐13:30 13:55‐14:20 Pray and lunch break Alireza Sari Jamshid Emami Analyses of animal structure and bionic Bionic and sustainable design 14:20‐14:45 Meysam Mobasheri Nanobiomimetics Time 8:30‐8:45 8:45‐9:00 Session 3 13:30‐13:55 14:45‐15:15 15:15‐15:30 Roundtable discussion/Closing ceremony Tea break Seminar Title Affiliation The role of biomimetics in future science University of Tehran Applications of natural compounds in biomimetic reactions Glycosylation optimization in Zitux (anti‐ CD therapeutic monoclonal antibody) Medicinal plants as sources for anticancer drugs University of Shahid Beheshti CinnaGen Co. Tehran University of Medical Sciences Sharif University of Technology Pasteur Institute of Iran Avicenna Research Institute University of Tehran University of Tehran Azad University of Science and Research of Tehran Most information related to the symposium cab can be found by browsing the website of Iran peptide Society at www.isobc.com or http://peptides.ut.ac.ir. ISOBC NEWSLETTER 2014 Volume 9, Number 1 The Valuable UNESCO Chair in Interdisciplinary Research in Diabetes at the University of Tehran World Wide Organization (WHO) reported that more than 180 million peoples suffer from diabetes and the total number of them will increase more than two times even 439 million people in 2030. Without any inhibiting strategies the mortality of diabetes will increases up to 50% in the next decade. Aging, population growth, new life styles, poor diets, obesity, inactivity and specially stress are the most important factors in the worldwide development of diabetes. Regards to Biophysics ability as a fundamental and cognitive knowledge field relative to high molecular basis identifying potential for diseases tracing, the valuable UNESCO chair in Interdisciplinary Research in Diabetes was established at Institute of Biochemistry and Biophysics of the University of Tehran in 2014 to follow the UNESCO important programs and activities. They comprise strengthening international academic cooperation in diabetes research and its application for natural development, associate the chair with the activities of other chairs, inter‐university network in different regions of the world, promote an integrated system of research, training, information and documentation activities in the area of Biophysics of Diabetes. The Federation of Iran Bioscience Societies (FIBS) The Federation of Iran Bioscience Societies (FIBS) was founded on 7th January 2014. The idea of establishing of the FIBS has been agreed at the first joint meeting of the 8 founders as core societies on 2nd February 2009, and then it was the first to receive approved bylaw and establishment license from Iran Scientific Associations Commission (ISAC). The aim of FIBS is to promote the scientific cooperation between bio‐science societies in Iran and other countries to stimulate basic and applied research and the dissemination of knowledge in all aspects of biological sciences. ISOBC NEWSLETTER 2014 Volume 9, Number 1 Biomacromolecular Journal (BMMJ) Biomacromolecular Journal (BMMJ) is an international and interdisciplinary journal covering investigations on the interactions of all macromolecules with biological systems. BMMJ welcomes high quality original papers in English dealing with experimental, theoretical and applied research related to all branches of Biophysical Chemistry, Biochemistry, Biophysics, Molecular Biology, Biosensors, Bioelectrochemistry, Bioinformatics and Nanobiotechnology. Review articles discussing specific areas of biology of current chemical or biological importance are also published. BMMJ ensures visibility of your research results to a worldwide audience in science. The journal publishes regular articles, letters and invited reviews. Manuscripts that fall outside the scopes and interests of the journal are returned to the Authors without in‐depth review. Relevant manuscripts are reviewed expeditiously with decisions generally made within 3 weeks from receipt. Reviews are published by invitation from the Editors, but suggestions are welcome at any time. BMMJ will be published by Iran Society of Biophysical Chemistry (ISOBC). More information: www.bmmj.org 2014 ISOBC NEWSLETTER Volume 9, Number 1 New Conferences: The 16th International Amine Oxidase Conference and Workshop 15th – 17th, July 2014 Garvan Institute for Medical Research, Sydney, Australia. More information: http://www.aoc2014.org/ 4th International Colloids Conference Surface Design & Engineering 1518 June 2014, Madrid, Spain More information: http://www.colloidsconference.com/ 10th International Conference on Protein Stabilisation 79 May 2014, Stresa (Lake Maggiore, Italy) More information: http://www.protstab2014.it/ 2014 ISOBC NEWSLETTER Volume 9, Number 1 The 2014 International Conference on Biology and Biomedical Engineering Venice, Italy, March 1517, 2014 More information: http://www.europment.org/conferences/2014/venice/bbe.htm The 2nd Annual International Conference on Science and Engineering in Biology, Medical and Public Health (BioMedPub 2014) Dynasty Resort Kuta Bali, Indonesia 31 May 01 June 2014 More information: http://biomedpub.org/ 2014 International Conference on Biochemistry and Biophysics(ICBB2014) 2014.5.165.18 Lushan, Jiangxi, China More information: http://www.c‐icbb.org/ 2014 ISOBC NEWSLETTER Volume 9, Number 1 17th International Cyclodextrin Symposium (ICS17) May, 29 31, 2014 at Saarland University in Saarbrücken ,Germany More information: www.uni-saarland.de/ics17 13th Laehnwitzseminar on Calorimetry – “Interplay between Nucleation, Crystallization, and the Glass Transition June 15 June 20 2014 Hotel "Am Alten Strom" RostockWarnemuende (at the Baltic Sea) Germany More information: http://www.polymerphysik.unirostock.de/laehnwitzseminar/laehnwitz_2014/laehnwitz_con_2014.php The 15th International Exhibition on Surfactant & Detergent Apr. 911, 2014 Shanghai Everbright Convention and Exhibition Center, China More information: http://www.iesdexpo.com/iesdchina/e_index.asp ISOBC NEWSLETTER 2014 Volume 9, Number 1 International Conference on Bioinformatics 2014 31st July to 2nd August 2014 Sydney, New South Wales, Australia More information: http://www.incob2014.org/ New book Advances in Protein and Peptide Sciences is an eBook series focused on leading-edge research on the structure, physical properties, and functions of proteins and peptides. The series presents highly cited contributions first published in the journal Current Protein and Peptide Science. Authors of these contributions have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in the field of protein and peptide chemistry and molecular biology, including membrane proteins and their interactions with ligands, computational methods, and proteins in disease and biotechnology. http://benthamscience.com/ebooks/9781608054879/ ISOBC NEWSLETTER 2014 Volume 9, Number 1 Interview Dr Salami and Dr. Moslehi shad are the co‐authors of a book entitled “Chemistry of Milk Proteins and its Application” and have an Iran Patent about production fermented camel milk. They are active members of ISOBC too. Here is an interview with them. Dr.Maryam Salami Please introduce yourself. My name is Maryam Salami I have a PhD in food science and Biotechnology and a postdoc in food biophysics from university of Tehran. I am a member of ISOBC. How you acquainted familiar with IBB? Profeesor Moosavi‐Movahedi was my supervisor during my PhD and after I graduated I became a postdoc at IBB. I would like to take this opportunity to thank professor Moosavi‐Movahedi for all his greatness and guidance it was an honor for me to work with such a wise person. What is your research area? During the last 6 years mostly I have worked and studied different bioactive peptides obtained from food source mostly from camel milk. I have done some research on anti glycation effect of some foods bioactive peptides and phenolic compounds. Here at IBB everything is based on team work. Different specialties come together to create multidisciplinary works. I am very grateful for working with such expert coworkers including Professor Moosavi Movahedi, Dr Moslehi‐Shad and Mrs. Poursasan. What are some of your latest achievements? Recently I have been a co‐author of a book entitled “Chemistry of Milk Proteins and its Application” which should be out any day now. I was also part of an expert team in producing a beneficial drink from camel milk the result of this work was established as a patent. Camel milk has lots of nutritional and medicinal benefit for human kind. The animal is a high tech animal. Many functional ingredients have been derived from this high tech animal so far. And more research is on the way. Also we worked on a project regarding this area which was supported by Iran national Science Foundation (INSF). ISOBC NEWSLETTER 2014 Volume 9, Number 1 Dr.Maryam Moslehi Shad Please introduce your self My name is Maryam Moslehi shad and I achieved Ph.D degree in the field of “Food Science & Technology”. I am a member of ISOBC and I became familiar with IBB during my Ph.D. What was your dissertation topic? My dissertation topic was “Fractionation and Identification of Bioactive Peptides from Bacterial Proteolysis of Fermented Camel and Bovine Milk products”. The aim of this study was to investigate the ACE‐inhibitory, antioxidant activity and antimicrobial properties of peptide fractions obtained from camel and bovine milk fermented using proteolytic strains of LAB during cold storage. It has been finished successfully under supervision of Prof. A.A. Moosavi‐Mohahedi and Dr. M.R. Ehsani. The articles which have been published till now from my dissertation are as follows: ‐The proteolytic activity of selected lactic acid bacteria in fermenting cow’s and camel’s milk and the resultant sensory characteristics of the products. International Journal of Dairy Technology. 66, 279‐285(2013). ‐ The comparative assessment of ACE‐inhibitory and antioxidant activities of peptide fractions obtained from fermented camel and bovine milk by Lactobacillus rhamnosus PTCC 1637. International Dairy Journal. 29, 82‐87(2013). What are some of your latest achievements? Recently, I was the co‐author of a book under the title of “Chemistry of Milk Proteins and its Application” under supervision of Prof. Moosavi‐Mohahedi. Furthermore, we had an Iran Patent No.29857 about production fermented camel milk which have been evaluated and approved by Iranian Research Organization for Science and Technology. Finally, I would like to appreciate Prof. Moosavi‐Movahedi due to all his supports and guidance. All of the above‐mentioned works were accomplished under his helpful supervision. New Website of ISOBC: http://isobc.com/ New Email of ISOBC: [email protected] ISOBC NEWSLETTER 2014 Volume 9, Number 1 New‐Rooz (Persian New Year) New‐Rooz, in word, means "New Day". It is the new day that starts the year, traditionally the exact astronomical beginning of the spring. Iranians consider No‐ Rooz as their biggest celebration of the year, before the New Year, they start cleaning their houses (Khaane Tekaani), and they buy new clothes. But a major part of New Year rituals is setting the "Haft Seen" with seven specific items. These seven things usually are: Seeb (apple), Sabze (green grass), Serke (vinager), Samanoo (a meal made out of wheat), Senjed (a special kind of berry), Sekke (coin), and Seer (garlic). Sometimes instead of Serke they put Somagh (sumac, an Iranian spice). Iranian used to place Quran on their Sofreh (spread) in order to bless the New Year and during "Saal Tahvil" reading some verses from it was popular. Mirrors are placed on the spread with lit candles as a symbol of fire. Happy New‐Rooz [email protected] Editor: Dr S. Hosseinkhani Executive Manager: N. Poursasan E‐mail: [email protected] IT Manager: A.Mohsenimehr
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