Peter B. Lockhart - UTHSCSA Dental School

CURRICULUM VITAE
NAME:
Peter B. Lockhart
OFFICE ADDRESS:
Department of Oral Medicine
Carolinas Medical Center
1000 Blythe Blvd.
Charlotte, NC 28232
EDUCATION:
1970
1975
BS
DDS
Guilford College, Greensboro, NC
University of North Carolina School of Dentistry
POSTDOCTORAL TRAINING:
1975-1977
General Practice Residency in Dentistry, Medical Center Hospital of Vermont
LICENSURE AND CERTIFICATION:
1987
North Carolina License Registration No. 5730
ACADEMIC APPOINTMENTS:
1977-1979
1979-1980
1980-1987
1992-1996
20012010-
Clinical Assistant Professor, Forsyth Dental Center, Boston, MA
Instructor in Oral Medicine and Oral Pathology, Harvard Schools of Medicine and Dental
Medicine
Assistant Professor of Oral Medicine and Oral Pathology, Harvard Schools of Medicine and
Dental Medicine
Clinical Professor of Diagnostic Sciences, University of North Carolina School of Dentistry,
Chapel Hill, NC
Visiting Professor, University of Glasgow Dental School, Glasgow, UK
Professor of Oral Medicine, Carolinas Medical Center, Charlotte, NC
HOSPITAL APPOINTMENTS:
1977-1979
1977-1987
1979-1982
1982-1987
1982-1987
1982-1987
1983-1987
1987-
Assistant in Surgery (Dentistry), Brigham and Women's Hospital, Boston
Consultant (Dentistry) to Division of Surgical Oncology, Dana Farber Cancer Institute, Boston
Junior Associate in Surgery (Dentistry), Brigham and Women's Hospital, Boston
Surgeon (Dentistry), Brigham and Women's Hospital, Boston
Consultant in Oral Surgery, New England Deaconess Hospital, Boston
Dentist in Charge, Hemostasis Unit of Brigham and Women's Hospital, Hemophilia Care
Facility for World Federation of Hemophilia
Consultant in Dental Surgery, Beth Israel Hospital, Boston
Attending Staff, Department of Dentistry, Carolinas Medical Center, Charlotte, NC
ADMINISTRATIVE AND TEACHING APPOINTMENTS:
1
1977-1981
1981-1987
1987-1994
19872001-
Program Coordinator, General Practice Residency in Dentistry, Brigham and Women's
Hospital, Boston
Director, General Practice Residency in Dentistry, Brigham and Women's Hospital, Boston
Director of Residency Training, Carolinas Medical Center, Charlotte, NC
Chair, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC
Chief, Department of Dentistry, Carolinas Medical Center, Charlotte, NC
MEMBERSHIPS IN SCIENTIFIC AND PROFESSIONAL SOCIETIES:
1973197519791979-2005
1982198319871991
1997
1999-2001
1999
2011-
American Dental Association
American Association of Hospital Dentists
American Academy of Oral Medicine
American Association of Dental Schools
International Association for Dental Research
Multinational Association for Supportive Care in Cancer
North Carolina Dental Society
American College of Dentists
Royal College of Surgeons of Edinburgh
National Academies of Practice
Royal College of Physicians and Surgeons of Glasgow
The Royal Society of Medicine, London
POSITIONS HELD IN SCIENTIFIC AND PROFESSIONAL ORGANIZATIONS:
1988-1995
19911992-1994
1992-1994
1992-1995
1992
19951998-2014
1998 1999 200420112011-
Consultant, Council on Dental Education/Commission on Dental Accreditation
Member, Council of Hospitals, American Association of Dental Schools
-Delegate
Board of Directors, American Cancer Society, North Carolina Division, Mecklenburg County
Unit
Reviewer, American Fund for Dental Health Grants Program
Consultant, National Institutes of Health
Reviewer, National Institutes of Health
Participant, 3rd, 4th, 5th and 6th World Workshops in Oral Medicine, Chicago, IL
Examiner, Royal College of Surgeons of Edinburgh
Dental Regional Advisor (USA), Royal College of Surgeons of Edinburgh
American Dental Association liaison to the American Heart Association’s Committee on
Rheumatic Fever, Endocarditis, and Kawasaki Disease
Consultant to Council on Access, Prevention and Interprofessional Relations, American Dental
Association
Specialty Consultants Panel for Pharmacist’s Letter and Prescriber’s Letter
COMMITTEE APPOINTMENTS:
1984-1986
19871987-1997
1990-1995
1988-2007
1990-1994
1990-2006
Chairman, Clinical Care Committee, Society for Oral Oncology
Graduate Medical Education Committee, Carolinas Medical Center
Fellowship Committee, American Association of Hospital Dentists
Chairman
Cancer Committee, Carolinas Medical Center
Research Advisory Committee, Carolinas Medical Center
Member, Board of Directors, Charlotte-Mecklenburg Health Services Foundation, Carolinas
2
1995-2001
1995-2010
200820102012-
Medical Center
Member, Health Services Foundation Grants Committee, Carolinas Medical Center
Co-Chair, Dental-Medical and Hospital Affairs Committee, American Academy of Oral
Medicine
Member, Cannon Research Grants Committee, Carolinas Medical Center
Member, Board of Trustees, American Academy of Oral Medicine
Chair, Research Committee, American Academy of Oral Medicine
FELLOWSHIPS, HONORS AND AWARDS:
1975
1975
1982
1991
1994
1997
1997
1999
2006
2010
2010
American Academy of Oral Roentgenology Student Award
International College of Dentists Journalism Award
Fellow, American Association of Hospital Dentists (No.13)
Fellow, American College of Dentists
World Health Organization Fellowship in Oral Medicine, London and Glasgow, UK
Fellowship in Dental Surgery, Royal College of Surgeons of Edinburgh
TC White Visiting Professorship in Oral Medicine, The Royal College of Physicians and
Surgeons of Glasgow, Scotland (3 months)
Fellowship in Dental Surgery, Royal College of Physicians and Surgeons of Glasgow
Samuel Charles Miller Award, American Academy of Oral Medicine
Lawrence J. Chasko Distinguished Service Award, American Association of Hospital Dentists
Fellowship (Honorary), British Society for Oral Medicine
EDITORIAL BOARDS POSITIONS:
2005- 2013
20072010-2013
2010-
Associate Editor, Journal of American Dental Association
Editorial Board, Journal of Applied Oral Science
Editorial Board, Journal of Dental Research
Editorial Board, Oral Surg Oral Med Oral Pathol Oral Radiol Endod.
REVIEWER POSITIONS:
1992-2000
2005200520052005200520062008200820082009201020112012-
Journal of Dental Education
Journal of Dental Research
Clinical Infectious Disease
Oral Biosciences and Medicine
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Oral Diseases
International Journal of Oral and Maxillofacial Surgery
New England Journal of Medicine
Bone Marrow Transplantation
Circulation
JAMA
Pediatrics
Annals of Internal Medicine
Clinical Oral Investigations
PATENTS:
10/08/2003
Erythema meter - #10/681722
3
03/01/2005
Erythema meter - #6,862,542
GRANTS AND CONTRACTS:
1979-1982
1979-1983
1984-1987
1990-1991
1990-1994
1991-1992
1992-1993
1992-1993
1993-2000
1994-1995
1995-1996
1995-1999
1995-1997
1995-1998
1997-1998
1997-2001
1997-2000
Co-Investigator, Residency Training in the General Practice of Dentistry. Department of
Health, Education, and Welfare - Public Health Service Grant #DH 11009-03
Co-Investigator, Residency Training in the General Practice of Dentistry. Robert Wood
Johnson Foundation
Principal Investigator, Residency Training in the General Practice of Dentistry. Department of
Health and Human Services - Public Health Service Grant #DH-11016-02. $248,887
Principal Investigator, A Multicenter, Double-Blind, Placebo-Controlled Evaluation of
Pilocarpine Hydrochloride in Head and Neck Cancer Patients for the Treatment of
Xerostomia Associated with Radiation-Induced Salivary Gland Hypofunction. MGI
PHARMA, Inc. #P90-01. $34,838
Principal Investigator, A Multicenter, Open Label, Maintenance of Pilocarpine Hydrochloride
in Head and Neck Cancer Patients for the Treatment of Xerostomia Associated with
Radiation-Induced Salivary Gland Hypofunction. MGI PHARMA, Inc. #P90-02. $17,928
Principal Investigator, The Effect of Chlorhexidine Mouthrinse on the Transient Bacteremia
Produced by Oral Surgical Procedures. The Charlotte-Mecklenburg Health Services
Foundation, Inc. $26,880
Principal Investigator, Initial Clinical Study of Controlled Release Pilocarpine in Normal
Volunteers. OraMed, Inc. #CP-001. $36,121
Principal Investigator, Phase II Dose Range Finding Clinical Study of Controlled Release
Pilocarpine Hydrochloride in Patients with Sjögren's Syndrome. OraMed. Inc. #CP-001.
$29,174
Co-Investigator, The Effect of the American Heart Association Guidelines on Bacteremia in
Children Following Extraction of Teeth in a Double-Blind Randomized Study. The
Charlotte-Mecklenburg Health Services Foundation, Inc. #012-645. $30,000
Principal Investigator, Benzydamine HCl in the Prophylactic Treatment of Postradiation Oral
Mucositis. Angelini Pharmaceuticals, Inc. $49,365
Principal Investigator, A Pilot Study of SNI-2011 in Patients with Sjögren's Syndrome
Experiencing Xerostomia and Keratoconjunctivitis Sicca. Snow Brand Milk Products Co.,
Ltd., Tokyo, Japan, #SB95US01. $18,580
Principal Investigator, Assessment of Toluidine Blue Rinse as an Aid to Clinical Exam in the
Identification of Recurrent or Second Primary Cancers of the Oral Cavity and in Biopsy Site
Selection in Patients with Previous Oral/Oropharyngeal and Other Upper Aerodigestive
Tract Squamous Cell Carcinoma. Zila Pharmaceuticals, Inc. #ZP-44389-01. $16,800
Principal Investigator, International Clinical Research Fellow in Oral Medicine. The
Charlotte-Mecklenburg Health Services Foundation, Inc. #012-904. $28,312
Principal Investigator, Development of a Comprehensive Multimedia Database for Oral
Medicine. The Charlotte-Mecklenburg Health Services Foundation, Inc. #012-791. $24,000
Principal Investigator, Low-Dose Natural Human Interferon Alpha (HBL IFN) Administered
by the Oral Mucosal Route for the Treatment of Sjögren’s Syndrome - A Phase II Clinical
Study. Veldona USA, Inc. #96-HU-SS-03. $18,000
Principal Investigator, A Double-Blind, Randomized, Placebo-Controlled Study to Determine
the Efficacy of Oral Pilocarpine Hydrochloride in the Moderation of Oral Mucositis in Stem
Cell Transplant Patients. MGI Pharma, Inc. $5,000; and The Charlotte-Mecklenburg Health
Services Foundation, Inc. #012-846. $14,189
Principal Investigator, Magnetic Resonance Imaging of the Maxillofacial Region. The
Charlotte-Mecklenburg Health Services Foundation, Inc. #012-966. $4,442
4
1997-2000
1998-2003
1998-2000
1999-2001
2000-2004
2002-2005
2002-2006
2003-2005
2003-2005
2003-2007
2004-2009
2005-2007
2005-2007
2006-2008
2006-2009
2006-2008
2008-2010
2009-
Principal Investigator, A Double-Blind, Dose Comparison Trial of Thalidomide for the
Treatment of Recurrent or Refractory Aphthous Stomatitis (RAS) in HIV-Infected Patients.
Celgene Corporation. $22,680
Principal Investigator, Effect of Amoxicillin on Bacteremia from the Oral Cavity. The
Charlotte-Mecklenburg Health Services Foundation, Inc. #012-836. $18,024
Principal Investigator, Low-Dose Natural Human Interferon Alpha (HBL IFNa) Administered
by the Oral Mucosal Route for the Treatment of Primary Sjögren’s Syndrome - A Phase III
Clinical Study. Veldona USA, Inc. (#98-HUSS05). $48,190
Principal Investigator, Low-Dose Natural Human Interferon Alpha (HBL IFNα) Administered
by the Oral Mucosal Route for the Treatment of Primary Sjögren’s Syndrome – An OpenLabel Phase III Clinical Study. Veldona USA, Inc. (#98-HUSS06). $19,791
Principal Investigator, Evaluation of Tolonium Chloride (Toluidine Blue) Rinse in the
Detection of Locally Recurrent or New Primary Oral Cavity Cancers and Cancer In Situ.
Zila, Inc. (ZIL-301-A1). $7,500
Principal Investigator, A Double-Blind, Randomized, Vehicle-Controlled Study Comparing
the Safety and Efficacy of Benzydamine Hydrochloride 0.15% Oral Rinse Including a
Separate Open-Label Standard of Care Arm in Subjects With Radiation-Induced Oral
Mucositis. McNeil Consumer & Specialty Pharmaceuticals. (#00-107). $90,750
Principal Investigator, Bacteremia from Dental Extractions vs Oral Hygiene. NIDCR #1 R01
DE13559-01A2. $1,700,000
Co-Investigator, Relationship Between Aspirin Use and Postoperative Bleeding From Dental
Extractions in a Healthy Population. Charlotte Mecklenburg Health Services Foundation,
Inc. (#0201-090). $1,505
Co-Investigator, Relationship Between Baseline Tissue mRNA Expression and Chemotherapy
Induced Mucositis. Charlotte Mecklenburg Health Services Foundation, Inc. (#0200-998).
$12,932
Principal Investigator, Role of Oral Bacteria in Ventilator-Associated Pneumonia (VAP).
Charlotte Mecklenburg Health Services Foundation, Inc. (#0201-179). $30,472
Co-Investigator, Changes in Oral Flora in Patients Undergoing Cancer Chemotherapy.
Charlotte Mecklenburg Health Services Foundation, Inc. (#0201-254). $19,862
Principal Investigator, Immune Response to Bacteremia from Dental Procedures. Charlotte
Mecklenburg Health Services Foundation, Inc. (#0201-287). $4,846
Principal Investigator, World Workshop on Oral Medicine IV. NIDCR #1 R13 DE01648001A1. $35,000
Co-Investigator, Determining the cause of oral mucositis following chemotherapy for cancer:
Molecular analysis of a unique archive of oral mucosal tissues from cancer patients who
underwent chemotherapy. Charlotte Freedland Foundation, Carolinas HealthCare System.
$25,000
Co-Investigator, Biological Validation of Differential Gene Expression in Buccal Mucosal
Specimens of Acute Myelogenous Leukemia Patients Exposed to Chemotherapy. Charlotte
Mecklenburg Health Services Foundation, Inc. $5,540
Co-Investigator, Randomized Pilot Trial of Hypnotherapy in Sjögren’s Syndrome Patients.
Charlotte Mecklenburg Health Services Foundation, Inc. $12,360
Principal Investigator, Determining the cause of oral mucositis following chemotherapy for
cancer: Molecular analysis of a unique archive of oral mucosal tissues from cancer patients
who underwent chemotherapy. Charlotte Freedland Foundation, Carolinas HealthCare
System. $27,000
Principal Investigator, Oral mucositis following Chemotherapy and Radiotherapy in Cancer
Patients at Carolinas Medical Center. Charlotte Freedland Foundation, Carolinas HealthCare
System. $9,900
5
20122012-2017
2012-
Principal Investigator, Osteonecrosis of the Jaw (ONJ) Case Registry. Amgen
Pharmaceuticals. $50,000
Co-Investigator, Clinical registry of dental outcomes in head and neck cancer patients.
NIDCR #1 U01 DE022939-01. $8,150,000
Co-Investigator, Oral Hygiene, Periodontal Disease and Infective Endocarditis: A Pilot
Study Cannon Research….
PUBLICATIONS:
JOURNALS:
1.
Lockhart PB, Sonis ST. Relationship of oral complications to peripheral blood leukocyte and
platelet counts in patients receiving cancer chemotherapy. Oral Surg Oral Med Oral Pathol 1979;
48(1):21-28.
2.
Nathanson D, Lockhart P. Delayed extraoral hypersensitivity to dental composite material. Oral
Surg Oral Med Oral Pathol 1979; 47:329-333.
3.
Stafford R, Sonis ST, Lockhart PB, Sonis A. Oral pathoses as diagnostic indicators in leukemia.
Oral Surg Oral Med Oral Pathol 1980; 50:134-139.
4.
Lockhart P, Sonis ST. Utilization of inpatients dental consultation services. Spec Care Dentist
1981; 1:18-21.
5.
Lockhart P. Gingival pigmentation as the sole presenting sign of chronic lead poisoning in a
mentally retarded adult. Oral Surg Oral Med Oral Pathol 1981; 52:143-149.
6.
Lockhart P, Sonis ST. Alterations in the oral mucosa caused by chemotherapeutic agents: A
histologic study. J Dermatol Surg Oncol 1981; 7(12):1019-1025.
7.
Stafford RF, Lockhart PB, Sonis AL, Sonis ST. Hematologic parameters as predictors of oral
involvement in the presentation of acute leukemia. J Oral Med 1982; 37-38-41.
8.
Connolly SF, Lockhart PB, Sonis ST. Severe oral hemorrhage and sepsis following bone marrow
transplant failure. Oral Surg Oral Med Oral Pathol 1983; 56(5):483-486.
9.
Connolly SF, Sonis ST, Lockhart PB. An unusually located early peripheral ameloblastoma (A case
report), J Oral Med 1984; 39:180-182.
10.
Ervin TJ, Weichselbaum R, Fabian R, Miller D, Norris Jr C, Posner M, Rose C, Lockhart PB, Tuttle
S, Macintyre J, Frei III E. Neoadjuvant cis-platinum bleomycin, methotrexate chemotherapy for
advanced squamous carcinoma of the head and neck: Arch Otolaryngol 1984; 110:241-245.
11.
Sonis ST, Clairmont F, Lockhart PB, Connolly SF. Benzydamine HCl in the management of
chemotherapy-induced mucositis, 1. Pilot Study. J Oral Med 1985; 40:67-71.
12.
Archibald D, Lockhart PB, Sonis ST, Ervin TJ, Fallon BG, Miller A, Clark JR. Oral complications of
multimodality therapy for advanced squamous cell carcinoma of the head and neck. Oral Surg Oral
Med Oral Pathol 1986; 61:139-141.
6
13.
Lockhart PB, Feldbau E, Gabel RA, Connolly SF, Silversin J. Dental complications during and after
tracheal intubation. J Am Dent Assoc 1986; 112:480-483.
14.
White BA, Lockhart PB, Connolly SF, Sonis ST. The use of infrared thermography in the evaluation
of oral lesions. J Am Dent Assoc 1986; 113:783-786.
15.
Lockhart PB, Crist D, Stone PH. The reliability of the medical history in the identification of
patients at risk for infective endocarditis. J Am Dent Assoc 1989; 119:417-422.
17.
Lockhart PB, Clark JR. Oral complications following neoadjuvant chemotherapy in patients with
head and neck cancer. NCI Monogr 1990; 9:99-101.
18.
Lockhart PB, Kutcher M. Oral considerations for the cancer patient. North Carolina Med J 1991;
52:549-556.
19.
Lockhart PB, Kim S, Lund N. Magnetic resonance imaging of human teeth. J Endod 1992; 18:237244.
20.
Lockhart PB, Kim S, Lund N. A comparison of micro magnetic resonance imaging and histology on
human teeth. Proc Finn Dent Soc 1992; 88:161-165.
21.
Lockhart PB, Alexander M, Pettice Y, Olsen R. Behavioral medicine training in dental residency
education. J Dent Educ 1992; 56:209-13.
22.
Lockhart PB, Clark JR. Pretherapy dental status of patients with malignant conditions of the head
and neck. Oral Surg Oral Med Oral Pathol 1994; 77:236-241.
23.
Badner VM, Lockhart PB, Hicks JL. The program director's perspective on the goals and objectives
of advanced general dentistry training. J Dent Educ 1994; 58:12-17.
24.
Lockhart PB. An analysis of bacteremias during dental extractions: A double-blind, placebocontrolled study of chlorhexidine. Arch Int Med 1996; 156(5):513-520.
25.
Lockhart PB, Fox PC, Gentry AC, Acharya R, Norton HJ. Pilot study of controlled-release
pilocarpine in normal subjects. Oral Surg Oral Med Oral Pathol 1996; 82(5):517-524.
26.
Lockhart PB, Gentry AC, Pulliam C, Curtis JW, Jr. Motivational factors in the choice of
postdoctoral general dentistry programs. J Dent Educ 1997; 61(3):297-304.
27.
Lockhart PB, Norris CM, Jr., Pulliam C. Dental factors in the genesis of malignancies of the oral
cavity. Oral Oncol 1998; 34(2):133-139.
28.
Hunter KD, Gibson J, Lockhart PB, Pithie A, Bagg J. Fluconazole resistant Candida species in the
oral flora of fluconazole-exposed HIV-seropositive patients. Oral Surg Oral Med Oral Pathol Oral
Radiol Endod 1998; 85:558-564.
29.
Lochary ME, Lockhart PB, Williams WT. Doxycycline and staining of permanent teeth. Pediatr
Infect Dis J 1998; 17(5):429-431.
7
30.
Lockhart PB. The risk for endocarditis in dental practice. Periodontol 2000 2000; 23:127-135.
31.
Lockhart PB, Mason DK, Konen JC, Kent ML, Gibson J. Prevalence and nature of orofacial and
dental problems in family medicine. Arch Fam Med 2000; 9(10):1009-1012.
32.
Epstein JB, Silverman S, Jr, Paggiarino DA, Crockett S, Schubert MM, Senzer NN, Lockhart PB,
Gallagher MJ, Peterson DE, Leveque FG. Benzydamine HCl for prophylaxis of radiation-induced
oral mucositis: Results from a multicenter, randomized, double-blind, placebo-controlled clinical
trial. Cancer 2001; 92(4):875-885.
33.
Fife RS, Chase WF, Dore RK, Wiesenhutter CW, Lockhart PB, Tindall E, Suen JY. Cevimeline for
the treatment of xerostomia in patients with Sjögren's Syndrome: A randomized trial. Arch Intern
Med 2002; 162:1293-1300.
34.
Lockhart PB, Brennan MT, Fox PC, Norton HJ, Jernigan DB, Strausbaugh LJ, the Infectious
Diseases Society of America Emerging Infections Network. Decision-making on the use of
antimicrobial prophylaxis for dental procedures: A survey of infectious disease consultants and
review. Clin Infect Dis 2002; 34:1621-1626.
35.
Brennan MT, Shariff G, Kent ML, Fox PC, Lockhart PB. Relationship between bleeding time test
and postextraction bleeding in a healthy control population. Oral Surg Oral Med Oral Pathol Oral
Radiol Endod 2002; 94:439-443.
36.
Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with
an acquired coagulopathy. Part I. Coagulopathies from systemic disease. Br Dent J 2003;
195(8):439-445.
37.
Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with
an acquired coagulopathy. Part II. Coagulopathies from drugs. Br Dent J 2003; 195(9):495-501.
38.
Lockhart PB, Brennan MT, Kent ML, Norton HJ, Weinrib DA: Impact of amoxicillin prophylaxis
on the incidence, nature, and duration of bacteremia in children after intubation and dental
procedures. Circulation 2004; 109(23):2878-2884.
39.
Shariff G, Brennan MT, Kent ML, Fox PC, Weinrib D, Burgess P, Lockhart PB. Relationship
between oral bacteria and hemodialysis access infection. Oral Surg Oral Med Oral Pathol Oral
Radiol Endod 2004; 98(4):418-422.
40.
Brennan MT, Bahrani-Mougeot F, Fox PC, Kennedy TP, Hopkins S, Boucher RC, Lockhart PB.
The role of oral microbial colonization in ventilator-associated pneumonia. Oral Surg Oral Med Oral
Pathol Oral Radiol Endod 2004; 98(6):665-72.
41.
Lockhart PB, Brennan MT, Sasser H, Ludlow J. Antepartum dental radiography and low birth
weight. [Letter] JAMA 2004; 292(9):1020.
42.
Runyon MS, Brennan MT, Batts JJ, Glaser TE, Fox PC, Norton HJ, Kent ML, Cox, TL, Lockhart
PB. Efficacy of penicillin for dental pain without overt infection. Acad Emerg Med 2004;
11(12):1268-1271
43.
Lockhart PB, Brennan MT, Kent ML, Packman CH, Norton HJ, Fox PC, Frenette G. Randomized,
8
controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous
blood stem cell transplantation. Bone Marrow Transplant 2005; 35:713-720.
44.
Brennan MT, Runyon MS, Batts JJ, Fox PC, Kent ML, Cox TL, H. Norton HJ, Lockhart PB.
Odontogenic signs and symptoms as predictors of odontogenic infection: A clinical trial. J Am Dent
Assoc 2006;137:62-66.
45.
Pike P, Parigger C, Splinter R, Lockhart P. Temperature distribution in dental tissue after interaction
with femtosecond laser pulses. Applied Optics. 2007; 46(34):8374-8.
46.
Valerin MA, Napenas JJ, Brennan MT, Fox PC, Lockhart PB. Modified Child-Pugh score as a
marker for postoperative bleeding from invasive dental procedures. Oral Surg Oral Med Oral Pathol
Oral Radiol Endod 2007;104(1):56-60.
47.
Grines CL, Bonow RO, Casey DE, Gardner TJ, Lockhart PB, Moliterno DJ, O’Gara, P, Whitlow P.
Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery
stents: A science advisory from the American Heart Association, American College of Cardiology,
Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and
American Dental Association, with representation from the American College of Physicians. J Am
Dent Assoc 2007; 138(5):652-5.
48.
Lockhart PB, Wray D, Peterson DE, Greenberg MS, eds. Fourth World Workshop on Oral Medicine.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103(3 suppl1).
49.
Baccaglini L, Brennan MT, Lockhart PB, Patton LL. World workshop on oral medicine IV: process
and methodology for systematic review and developing management recommendations. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod 2007; 103(3 suppl1):S3.e1-S3.e19
50.
Brennan M, Migliorati CA, Lockhart PB, Wray D, Al-Hashimi I, Axéll T, Bruce AJ, Carpenter W,
Eisenberg E, Epstein JB, Holmstrup P, Jontell M, Nair R, Sasser H, Schifter M, Silverman B,
Thongprasom K, Thornhill M, Warnakulasuriya S, van der Waal, I. Management of oral epithelial
dysplasia: a review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103(3 suppl1):S19.e1S19.e12
51.
Al-Hashimi I, Schifter M, Lockhart PB, Wray D, Brennan M, Migliorati CA, Axéll T, Bruce AJ,
Carpenter W, Eisenberg E, Epstein JB, Holmstrup P, Jontell M, Lozada-Nur F, Nair R, Silverman B,
Thongprasom K, Thornhill M, Warnakulasuriya S, van der Waal, I. Oral lichen planus and oral
lichenoid lesions: diagnostic and therapeutic considerations. Oral Surg Oral Med Oral Pathol Oral
Radiol Endod 2007; 103(3 suppl1):S25.e1-S25.e12
52.
von Bültzingslöwen I, Sollecito TP, Fox PC, Daniels T, Jonsson R, Lockhart PB, Wray D, Brennan
MT, Carrozzo M, Gandera B, Fujibayashi T, Navazesh M, Rhodus NL, Schiødt M. Salivary
dysfunction associated with systemic diseases: systematic review and clinical management
recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103(3 suppl1):S57.e1S57.e15
53.
Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, Bolger A, Cabell CH,
Takahashi M, Baltimore RS, Newburger JW, Strom BL, Tani LY, Gerber M, Bonow RO, Pallasch T,
Shulman ST, Rowley AH, Burns JC, Ferrieri P, Gardner T, Goff D, Durack DT. Prevention of
Infective Endocarditis. Guidelines From the American Heart Association. A Guideline From the
9
American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee,
Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council
on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research
Interdisciplinary Working Group. Circulation 2007; 115.
54.
Lockhart PB, Loven B, Brennan MT, Fox PC. The evidence base for the efficacy of antibiotic
prophylaxis in dental practice. J Am Dent Assoc 2007; 138(4):458-74.
55.
Grines CL, Bonow RO, Casey DE, Gardner TJ, Lockhart PB, Moliterno DJ, O’Gara, P, Whitlow P.
Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery
stents: A science advisory from the American Heart Association, American College of Cardiology,
Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and
American Dental Association, with representation from the American College of Physicians.
Circulation 2007; 115(6):813-8.
56.
Brennan MT, Kent ML, Fox PC, Norton HJ, Lockhart PB. The impact of oral disease and
nonsurgical treatment on bacteremia in children. J Am Dent Assoc 2007; 138(1):80-5.
57.
Bahrani-Mougeot FK, Paster BJ, Coleman S, Barbuto S, Brennan MT, Noll J, Kennedy T, Fox PC,
Lockhart PB. Molecular analysis of oral and respiratory bacterial species associated with ventilatorassociated pneumonia. J Clin Microbiol 2007: 45(5):1588-93.
58.
Napeñas JJ, Brennan MT, Bahrani-Mougeot FK, Fox PC, Lockhart PB. Relationship between
mucositis and changes in oral microflora during cancer chemotherapy. Oral Surg Oral Med Oral
Pathol, Oral Radiol, Endod 2007; 103(1):48-59.
59.
Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, Bolger A, Cabell CH,
Takahashi M, Baltimore RS, Newburger JW, Strom BL, Tani LY, Gerber M, Bonow RO, Pallasch T,
Shulman ST, Rowley AH, Burns JC, Ferrieri P, Gardner T, Goff D, Durack DT. Prevention of
Infective Endocarditis. Guidelines From the American Heart Association. A Guideline From the
American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee,
Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council
on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research
Interdisciplinary Working Group. J Am Dent Assoc 2007; 138:739-760.
60.
Nicopoulos M, Brennan MT, Kent ML, Brickhouse TH., Rogers MK, Fox PC, Lockhart PB. Oral
health needs and barriers to dental care in hospitalized children. Spec Care Dent 2007; 27(5):206-11.
61.
Kent ML, Brennan MT, Noll JL, Fox PC, Burri SH, Hunter JC, Lockhart PB. Radiation-induced
trismus in head and neck cancer patients. Support Care Cancer 2008; 16:305-309.
62.
Bahrani-Mougeot FK, Paster BJ, Coleman S, Ashar J, Knost S, Sautter RL, Lockhart PB.
Identification of oral bacteria in blood cultures by conventional versus molecular methods. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod 2008; 105(6):720-4.
63.
Lockhart PB, Brennan MT, Sasser HC, Fox PC, Paster BJ, Bahrani-Mougeot FK. Bacteremia
associated with toothbrushing and dental extraction. Circulation 2008; 117:3118-25.
64.
Bahrani-Mougeot FK, Paster BJ, Coleman S, Ashar J, Barbuto S, Lockhart PB. Diverse and Novel
Oral Bacterial Species in Blood Following Dental Procedures. J Clin Microbiol 2008; 46(6):2129-32.
10
65.
Brennan MT, Hong C, Furney SL, Fox PC, Lockhart PB. Utility of an international normalized ratio
testing device in a hospital-based dental practice. J Am Dent Assoc 2008; 139(6):697-703.
66.
Brennan MT, Valerin MA, Noll JL, Napeñas JJ, Kent ML, Fox PC, Sasser HC, Lockhart PB. Aspirin
use and postoperative bleeding from dental extractions. J Dent Res 2008; 87(8):740-4.
67.
Lockhart PB. Guidelines for prevention of infective endocarditis: an explanation of the changes. J
Am Dent Assoc 2008; 139 Suppl:2S.
68.
Bahrani-Mougeot FK, Thornhill M, Sasser H, Marriott I, Brennan MT, Papagerakis S, Coleman S,
Fox PC, Lockhart PB. Systemic host immuno-inflammatory response to dental extractions and
periodontitis. Oral Surg Oral Med Ora Pathol Oral Radiol Endod 2008; 106(4):534-41.
69.
Thelin WR, Brennan MT, Lockhart PB, Singh ML, Fox PC, Papas AS, Boucher RC. The oral
mucosa as a therapeutic target for xerostomia. Oral Dis 2008; 14(8):683-9.
70.
Lockhart PB, Brennan MT, Sasser HC, Fox PC, Paster BJ, Bahrani-Mougeot FK. Response to letter
by Kaplan regarding “Bacteremia associated with toothbrushing and dental extraction”. Circulation
2009; 119:e14.
71.
Lockhart PB, Brennan MT, Cook WH, Sasser H, Lovell RD, Skipper ER, Noll J, Cox TL, Aten DJ,
Cook JW. Concomitant surgical treatment of dental and valvular heart diseases. Oral Surg Oral Med
Oral Pathol Oral Radiol Endod 2009; 107(1):71-6.
72.
Hong CH, Brennan MT, Lockhart PB. Incidence of acute oral sequelae in pediatric patients
undergoing chemotherapy. A review of the literature. Pediatr Dent. 2009; 31(5):420-425.
73.
Napeñas JJ, Hong CH, Brennan MT, Furney SL, Fox PC, Lockhart PB. The frequency of bleeding
complications after invasive dental treatment in patients receiving single and dual antiplatelet
therapy. J Amer Dent Assoc 2009 Jun 140(6):690-5.
74.
Napeñas JJ, Lockhart PB, Epstein JB. Comment on the 2009 American Academy of Orthopaedic
Surgeons’ Information Statement on Antibiotic Prophylaxis for Bacteremia in Patients with Joint
Replacements. J Can Dent Assoc Jul/Aug 75(6): 447-9.
75.
Lockhart PB, Brennan MT, Thornhill M, Michalowicz B, Noll J, Bahrani-Mougeot FK, Sasser HC.
Poor Oral Hygiene is a Risk Factor for Infective Endocarditis-Related Bacteremia. J Am Dent Assoc
2009 Oct; 140:1238-44.
76.
Baddour LM, Epstein AE, Erickson CC, Knight BP, Levison ME, Lockhart PB, Masoudi FA, Okum
EJ, Wilson WR, Beerman LB, Bolger AF, Estes III, NA, Gewitz M, Newburger JW, Schron EB,
Taubert KA; on behalf of the American Heart Association Rheumatic Fever, Endocarditis, and
Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on
Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Nursing; Council on Clinical
Cardiology; and the Interdisciplinary Council on Quality of Care and Outcomes Research. Update on
cardiovascular implantable electronic device infections and their management: a scientific statement
from the American Heart Association. Circulation 2010; 121:000-000.
77.
Hong CH, Brennan MT, Lockhart PB. Incidence of acute oral sequelae in pediatric patients
11
undergoing chemotherapy. A review of the literature. Pediatr Dent. 2009; 31(5):420-425.
78.
Bensadoun RJ, Riesenbeck D, Lockhart PB, Elting LS, Spijkervet FKL, Brennan MT. Trismus
Section, Oral Care Study Group, Multinational Association for Supportive Care in Cancer
(MASCC)/International Society of Oral Oncology (ISOO). A systematic review of trismus induced
by cancer therapies in head and neck cancer patients. Support Care Cancer. 2010 18(8):1033-1038.
79.
Napeñas JJ, Brennan MT, Coleman S, Kent ML, Noll J, Frenette G, Nussbaum ML, Mougeot JL,
Paster BJ, Lockhart PB, Bahrani-Mougeot FK. Molecular methodology to assess the impact of
cancer chemotherapy on the oral bacterial flora: a pilot study. Oral Surg Oral Med Oral Pathol Oral
Radiol Endod. 2010 Apr; 109(4):554-60.
80.
Little JW, Jacobson JJ, Lockhart PB. The dental treatment of patients with joint replacements: A
position paper from the American Academy of Oral Medicine. J Am Dent Assoc. 2010;141(6):667671.
81.
Hong CHL, Allred R, Napenas JJ, Brennan, MT, Baddour LM, Lockhart PB. Antibiotic prophylaxis
for dental procedures to prevent indwelling venous catheter-related infections. Am J Med 2010;
123:1128-33.
82.
Sankar V, Hearnden V, Hull K, Juras DV, Greenberg M, Kerr AR, Lockhart PB, Patton LL, Porter S,
Thornhill M. Local Drug Delivery for Oral Mucosal Diseases: Challenges and Opportunities. Oral
Diseases. 2011; 17 Suppl. 1), 73-84.
83.
Baddour LM, Epstein AE, Erickson CC, Knight BP, Levison ME, Lockhart PB, Masoudi FA, Okum
EJ, Wilson WR, Beerman LB, Bolger AF, Estes III, NA, Gewitz M, Newburger JW, Schron EB,
Taubert KA; Update on cardiovascular implantable electronic device infections and their
management: a scientific statement from the American Heart Association. J Am Dent Assoc
2011;142(2):159-165.
84.
Thornhill MH, Dayer MJ, Forde JM, Corey GR, Chu VH, Couper DJ, Lockhart PB: Impact of the
NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective
endocarditis: before and after study. BMJ 2011;342:d2392 do:10.1136/BMJ.d2392.
85.
Rouleau TS, Shychuk AJ, Kayastha J, Lockhart PB, Nussbaum ML, Brennan MT.A retrospective,
cohort study of the prevalence and risk factors of oral burning in patients with dry mouth. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod. 2011 Jun;111(6):720-5.
86.
Mougeot JLC, Bahrani-Mougeot FK, Lockhart PB, Brennan MT. Microarray analyses of oral punch
biopsies from AML patients treated with chemotherapy. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod. 2011 112:446-452.
87.
Napeñas JJ, Hong CH, Kempter E, Brennan MT, Furney SL, Lockhart PB. Selective serotonin
reuptake inhibitors and oral bleeding complications after invasive dental treatment. Oral Surg Oral
Med Oral Pathol Oral Radiol Endod. 2011. 112:463-467.
88.
Hearnden V, Sankar V, Hull K, Vidović Juras D, Greenberg M, Kerr A, Lockhart PB, Patton LL,
Porter S, Thornhill M. New developments and opportunities in mucosal drug delivery for local and
systemic disease. Advanced Drug Delivery Reviews. 64 (2012) 16-28.
12
89.
Hong CH, Napenas JJ, Brennan MT, Furney SL, Lockhart PB. Risk of postoperative bleeding after
dental procedures in patients on warfarin: A Retrospective Study. Oral Surg Oral Med Oral Pathol
Oral Radio . 2012. 114:464-468.
90.
Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, Levinson ME,
Taubert KA, Newburger JW, Gornik HL, Gewitz MH, Wilson WR, Smith Jr SC, Baddour
LM; on behalf of the American Heart Association Rheumatic Fever, Endocarditis, and
Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young,
Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and
Council on Clinical Cardiology. Periodontal Disease and Atherosclerotic Vascular Disease:
Does the Evidence Support an Independent Association? A Scientific Statement From the
American Heart Association. Circulation. 2012;125:00-00.
91.
Lockhart PB. Antibiotic Prophylaxis for Dental Procedures: Are We Drilling in the Wrong
Direction? Circulation 2012:126:11-12. (solicited editorial)
92.
Hong CH, Scobey MW, Napenas, JJ, Brennan, MT, Lockhart PB. Dental Post-operative Bleeding
Complications in Patients with Suspected and Documented Liver Disease. Oral; Diseases Oral Dis.
2012 Oct;18(7):661-6.
94.
Likar K, Stewart C, Al-Hashimi I, Curtis W, Berg K, Cherian K, Lockhart PB, Brennan MT.
Prevalence of Oral Lesions of Autoimmune Etiology in Patients with Primary Sjögren’s Syndrome.
Oral Diseases (In press)
95. Mougeot, J-L C, Bahrani-Mougeot, FK, Peterson, DE, Padilla, RJ, Brennan, MT and Lockhart, PB.
Microarray Analysis of a Unique Archive of Oral Mucosal Autopsy samples from Cancer
Chemotherapy Patients. Oral Surg Oral Med Oral Pathol. 2013.115:345-353.
96. Lockhart PB, Garvin KL, Osmon DR, Hewlett AL, Scuderi Giles, Lewallen D, Vail T. The
Antibiotic Prophylaxis Guideline for Prosthetic Joints: Trying To Do the Right Thing (Editorial). J
Am Acad Orthop Surg 2013;21:193-194.
97. Napenas JJ, Oost FCD, deGroot A, Loven B, Hong CHL, Brennan MT, Lockhart PB, van Diermen
DE. Review of postoperative bleeding risk in dental patients on antiplatelet therapy. Oral Surg Oral
Med Oral Pathol. 2013.115:491-499.
98. Lockhart PB, Blizzard J, Maslow AL, Brennan MT, Sasser H, Carew J. Drug cost implications for
antibiotic prophylaxis for dental procedures. Oral Surg Oral Med Oral Pathol. 2012.115:345-353.
99. Wingard JR, Walsh TJ, Redding SW, Wade JC, Cohen JI, Donnelly JP, Lockhart PB, Klastyersky J,
Raber-Durlacher, JE. Oral mucositis in high-dose chemotherapy. JNCI (In press).
100.
Lockhart PB. Antibiotic Prophylaxis Guidelines for Prosthetic Joints: Much Ado about Nothing?
(Editorial). Oral Surg Oral Med Oral Pathol. (In press).
BOOKS AND CHAPTERS:
1.
Lockhart P: Dental management of patients receiving chemotherapy. In: Oral Complications of
Cancer Chemotherapy. Eds. Peterson D, Sonis ST, Nijhoff Publishing Company, pp. 113-48, 1983.
13
2.
Sonis ST, Lockhart PB: Oral complications of chemotherapy and their management. In: Oral
Cancer. Ed. Shklar G, W.B. Saunders Co., pp. 186-201, 1984.
3.
Lockhart PB, Connolly SF, Sargent KT, Sonis ST, Eds: A Practical Guide to Hospital Dental
Practice. MASCO Publishing Company, 1985.
4.
Lockhart PB: Prevention and management of head and neck complications of radiotherapy. In:
Head and Neck Management of the Cancer Patient. Eds. Peterson D, Elias G, Sonis ST; Nijhoff
Publishing Company, pp. 429-49, 1986.
5.
Lockhart PB, Connolly SF, Sargent RK, Eds: A Practical Guide to Hospital Dental Practice. 2nd
Edition. Corporate Visions Publishing Company, 1989.
6.
Lockhart PB, Connolly SF, Sargent RK, Eds: A Practical Guide to Hospital Dental Practice. 3rd
Edition. JBK Publishing Co., Portland, OR, 1991.
7.
Lockhart PB, Schmidtke MA: Antibiotic considerations in medically compromised patients. In:
Practical Considerations in Special Patient Care, Dental Clinics of North America. Ed. Rutkauskas
J, W.B. Saunders Company, Vol 38:381-402, 1994.
8.
Lockhart PB, Ed: Oral Medicine and Hospital Practice, 4th Edition. Federation of Special Care
Organizations in Dentistry, Chicago, IL, 1997.
9.
Lockhart PB, Durack DT: Oral microflora as a cause of endocarditis and other distant site
infections. In: Infectious Disease Clinics of North America. Ed. Rutkauskas, JS, W.B. Saunders
Company, Vol 13(4):833-850, 1999.
10.
Brennan MT, Shariff G, Lockhart PB, Fox PC. Treatment of xerostomia: a systematic review of
therapeutic trials. In: Dental Therapeutics Update, Dental Clinics of North America. Ed. Moore PA
and Hersh EV, Elsevier Science, 46(4):847-856, 2002.
11.
Lockhart PB, Ed: Dental Care of the Medically Complex Patient. 5th Edition. Elsevier Science
Limited, Edinburgh, UK, 2004.
12.
Brennan MT, Valerin MA, Napenas JJ, Lockhart PB. Oral manifestations of patients with lupus
erythematosus. Dental Clinics of North America. 49(1):127-41, 2005.
13.
Lockhart PB, Littmann, L, Glick M. Diseases of the cardiovascular system. In: Burket's Oral
Medicine: Diagnosis and Treatment. Eds. Greenberg MS, Glick M, Ship JA, BC Decker Inc.,
Hamilton Ontario, 2008.
14.
Ship JA, Brennan MT, Greenberg M, Lockhart PB, Redding S, Sankar V, Sirois D, Wray D.
Pharmacology. In: Burket's Oral Medicine: Diagnosis and Treatment. Eds. Greenberg MS, Glick M,
Ship JA, BC Decker Inc., Hamilton Ontario, 2008.
15.
Brennan MT, Woo SB, Lockhart PB. Dental treatment planning and management in the patient who
has cancer. In: Management of the oncologic patient, Dental Clinics of North America. Eds. Woo,
SB, Treister NS. W.B. Saunders Company, Vol. 52(1):19-37, 2008.
14
16.
Lockhart PB. Cardiovascular Disease. In: Clinician’s Guide: Medically Complex Dental Patients. 3rd
Edition. Eds. Rhodus NL, Miller CS, BC Decker Inc., Hamilton Ontario, 2008.
17.
Brennan M, Lockhart P. Oral Assessment. In: Oral Complications of Cancer and its Management.
Eds. Davies AN, Epstein JB, Oxford University Press, Oxford, New York, 2010.
18.
Lockhart PB, Hong, CHL, van Diermen DE. The Influence of Systemic Diseases on the Diagnosis of
Oral Diseases: a Problem-Based Approach. In: Dental Clinics of North America. Dental Clinics of
North America. 55(1):15-28, 2011.
19.
Greenberg MS, Hodgson T, Jontell M, Kerr AR, Lockhart PB, Peterson DE, Wray D, Editors.
Proceedings of the Fifth World Workshop in Oral Medicine. Oral Diseases (2011) 17 (Suppl. 1), 1-6.
20.
Lockhart PB, Furney S: Medical Issues in the Care of Older Adults. In: Textbook of Geriatric
Dentistry. Eds. Holm-Pedersen, Walls, and Ship JA, Blackwell Publishing, (In Press).
21.
Lockhart PB. Antibiotic prophylaxis. In: The Clinicians Guide to Pharmacology. BC Decker, Inc.,
(In Press)
22.
Lockhart PB, Ed: Oral Medicine and Medically Complex Patients. 6th Edition. Wiley-Blackwell.
2013.
ABSTRACTS:
1.
Lockhart P, Sonis S, Shklar G: Histologic changes of oropharyngeal mucosa in cancer
chemotherapy. J Dent Res Special Issue A. 1980; 59:375.
2.
Stafford R, Sonis S, Lockhart PB, Sonis A: Hematologic parameters as predictors of oral
involvement in leukemia. J Dent Res Special Issue A. 1980; 59:409.
3.
White BA, Lockhart PB, Connolly SF, Sonis ST: The use of infrared thermography in the evaluation
of oral lesions. 2nd World Conference on Inflammation, Monte Carlo, 1986.
4.
Lockhart PB: The significance of cardiac murmurs in medical history taking in dental practice.
American Academy of Oral Medicine 42nd Annual Meeting, San Francisco, 1988.
5.
Lockhart PB, Clark J: Oral complications following induction cancer chemotherapy in patients with
head and neck cancer. NIH Consensus Development Conference on Oral Complications of Cancer
Therapies: Diagnosis, Prevention and Treatment, Bethesda, 1989.
6.
Kountz JM, Lockhart PB: Emergency dental treatment: Age determinants in a clinic population.
International Association for Dental Research, Cincinnati, 1990.
7.
Lockhart PB, Connolly SF, Rappaport JM: Oral sequelae following bone marrow transplantation for
aplastic anemia. International Association for Dental Research, Cincinnati, 1990.
8.
Kountz JM, Lockhart PB, Olsen R: Impact of physical health on dental use behaviors. International
Association for Dental Research, Acapulco, Mexico, 1991.
15
9.
Lockhart PB, Norton J, Clark J: Preradiotherapy dental status of patients with head and neck tumors.
American Association for Dental Research, Boston, 1992.
10.
Lockhart PB, Kim S: Histologic confirmation of magnetic resonance images of human teeth.
International Association for Dental Research, Glasgow, Scotland, 1992.
11.
Lockhart PB, Norton J, Gentry A, Williams WT: Analysis of bacteremias during tooth extractions.
Second International Congress on Oral Medicine, Edinburgh, Scotland, 1992.
12.
Lockhart PB, Connolly SF: Nature and importance of dental consultation services for hospitalized
patients. International Association for Dental Research, Seattle, WA, 1994.
13.
Badner VM, Lockhart PB: The program director's perspective on the goals and objectives of
advanced general dentistry training. American Association of Dental Schools, Seattle, WA, 1994.
14.
Lockhart PB, Pulliam C: Dental factors in the genesis of malignancies of the head and neck. 9th
Annual Meeting of the International Society for Oral Oncology. National Institutes of Health,
Bethesda, MD, 1994.
15.
Lockhart P, Gentry A, Mehta, B, Fox PC, and Acharya, R: Pilot study of a controlled-release
formulation of pilocarpine hydrochloride. American Academy of Oral Medicine, Nashville, TN,
1995.
16.
Kountz JM, Lockhart PB, Lawhorne HL, Anderson WE: Perceived dental problems in an HIVpositive population. Third International Workshop on the Oral Manifestations of HIV Infection,
London, UK, 1996.
17.
Lockhart P, Madden T: Immunosuppression and complications following dental extractions. Third
International Workshop on the Oral Manifestations of HIV Infection, London, UK, 1996.
18.
Lockhart P, Lochary M, Callen M: Incidence, nature, and duration of bacteremia from dental
procedures in children randomized to amoxicillin versus placebo. 4th International Symposium on
Modern Concepts in Endocarditis and Cardiovascular Infections, Yverdon-les-Bains, Switzerland,
1997.
19.
Lockhart PB, Paggiarino DA, Gallagher MJ, Senzer NN, Schubert MM: Efficacy of benzydamine
HCl in the prevention and management of irradiation oral mucositis in head and neck cancer
patients: A multicenter, double-blind, randomized, placebo-controlled study. 5th International
Congress on Oral Cancer, London, 1997.
20.
Hunter KD, Bagg J, Gibson J, Lockhart PB: The effects of fluconazole treatment on the oral
mycological flora in HIV seropositive patients. International Association of Dental Research, Nice,
France, 1998.
21.
Kountz, JM, Kent ML, Lockhart PB: Illumination by three portable lights compared to dental
operatory lighting. International Association of Dental Research, Vancouver, Canada, 1999.
22.
Kountz JM, Kaufman JS, Escott JA, Lockhart PB: Access to dental and medical services:
Mecklenburg County, North Carolina. International Association of Dental Research, Vancouver,
16
Canada, 1999.
23.
Brennan MT, Lockhart PB, Fox PC, Norton HJ, Strausbaugh LJ: Infectious disease specialists’ use
of antimicrobial prophylaxis for dental procedures. Annual Meeting of the American Academy of
Oral Medicine, Montreal, Canada, 2001.
24.
Shariff G, Brennan MT, Kent L, Fox PC, Lockhart PB: Correlation of cutaneous versus dental
extraction socket bleeding in a healthy control population. Annual Meeting of the American
Academy of Oral Medicine, Montreal, Canada, 2001.
25.
Lockhart PB, Brennan MT, Fox PC, Lochary ME, Zukaitis K: Impact of amoxicillin on the
incidence and nature of bacteremia following nasal intubation. 6th International Symposium on
Modern Concepts in Endocarditis and Cardiovascular Infections, Barcelona, Spain, 2001.
26.
Strausbaugh LJ, Lockhart PB, Brennan MT, Jernigan DB, Liedtke LA, the Infectious Diseases
Society of America Emerging Infections Network: Antimicrobial prophylaxis for dental procedures:
view of infectious diseases consultants. 11th Annual Meeting of the Society for Healthcare
Epidemiology of America, Toronto, Canada, 2001.
27.
Lockhart PB, Brennan MT, Kent ML, Fox PC: Impact of amoxicillin on the incidence, nature, and
duration of dental bacteremia. 56th Annual meeting of the American Academy of Oral Medicine, Ft.
Lauderdale, 2002.
28.
Brennan MT, Shariff G, Lockhart PB, Fox PC: Systematic review of xerostomia therapeutic trials.
56th Annual meeting of the American Academy of Oral Medicine, Ft. Lauderdale, 2002.
29.
Shariff G, Brennan MT, Kent ML, Fox PC, Burgess P, Weinrib D, Lockhart PB: Relationship
between oral microflora and hemodialysis access infection. 56th Annual Meeting of the American
Academy of Oral Medicine, Ft. Lauderdale, 2002.
30.
Lockhart PB, Brennan MT, Frenette G, Kent ML, Fox PC, Packman CH, Norton HJ: Pilocarpine
hydrochloride is ineffective in the moderation of oral mucositis in stem cell transplantation.
Supportive Care in Cancer 2002; 10(4):363.
31.
Lockhart PB, Brennan MT, Aten DJ, Cook WH, Skipper ER, Cook JW: Concomitant surgical
treatment of valvular heart disease and dental disease. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 2003; 95(4):419.
32.
Valerin M, Brennan MT, Gruber H, Padilla R, Ullrich C, Lockhart PB: Magnetic resonance imaging
as a diagnostic tool for pulpal status. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;
95(4):423.
33.
Kent ML, Nicopoulos M, Brennan MT, Hughes TL, Rogers MK, Fox PC, Lockhart PB: The
prevalence of oral disease and unmet dental needs in medically compromised children. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod 2003; 95(4):419.
34.
Brennan MT, Runyon MS, Batts JJ, Kent ML, Fox PC, Cox TL, Norton J, Lockhart PB: The impact
of antibiotics on odontogenic pain outcomes in an emergency department. Oral Surg Oral Med Oral
Pathol Oral Radiol Endod 2003; 95(4):416-417.
17
35.
Lockhart PB, Brennan MT, Loven B, Sasser H. Cost of antibiotic prophylaxis prior to invasive
dental procedures in patients felt to be at risk for distant site infection. Oral Surg Oral Med Oral
Pathol Oral Radiol Endod 2004; 97(4):452.
36.
Valerin MA, Brennan MT, Napenas JJ, Fox PC, Lockhart PB: Modified Child-Pugh score as a
predictor for postoperative bleeding from invasive dental procedures. Oral Surg Oral Med Oral
Pathol Oral Radiol Endod 2004; 97(4):456.
37.
Napenas JJ, Brennan MT, Fox PC, Lockhart PB: Oral microflora changes in patients receiving
chemotherapy: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;
97(4):452-453.
38.
Brennan MT, Kent ML, Mostafavi Z, Frenette GP, Fox PC, Lockhart PB. Gene expression changes
in buccal mucosal tissue 2 days post-chemotherapy in acute myelogenous leukemia (AML) patients.
Annual Meeting of the American Society of Clinical Oncology, Orlando, Florida, 2005.
39.
Bahrani-Mougeot F, Paster BJ, Ashar J, Barbuto S, Coleman S, Brennan MT, Kent M-L, Noll J,
Lockhart PB. Novel oral bacterial species isolated from the blood of subjects with periodontal
disease and dental caries. Tsukuba, Japan. ICCC-10. 5-14, p. 518. Oct 2004.
40.
Bahrani-Mougeot F, Paster BJ, Coleman S, Barbuto S, Brennan MT, Noll J, Lockhart PB.
Identification of oral bacteria involved in ventilator-associated pneumonia. Second International
Congress on Pulmonary Disease, Intensive Care and Tuberculosis” November 15-18, 2005, TehranIran. Nov. 2005.
41.
Napenas JJ, Brennan, MT, Bahrani-Mougeot F, Frenette G, Fox PC, Kent ML, Noll J, Coleman S,
Asher J, Lockhart PB. Use of molecular methodology to characterize oral bacterial flora in patients
undergoing cancer chemotherapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005.
42.
Valerin MA, Brennan MT, Noll JL, Napeñas JJ, Kent ML, Fox PC and Lockhart PB Relationship
between aspirin use and postoperative bleeding from dental extractions in a healthy population,
OOOOE, 2006: 102(3):326.
43.
Bahrani-Mougeot FK, Paster BJ, Coleman S, Barbuto S, Brennan MT, Noll J, Miles W, Lockhart
PB. Molecular-based support for role of oral bacteria in ventilator-associated pneumonia. 84th
General Session and Exhibition of the International Association for Dental Research, Brisbane,
Australia, 2006.
44.
Lockhart PB, Brennan MT, Sasser H, Noll J, Coleman S, Ashar J, Kent ML, Fox PC, Paster BJ,
Bahrani-Mougeot FK. Tooth extraction and tooth brushing both produce bacteremia of endocarditisrelated pathogens. J Am Coll Cardiol 2007; 49(9 supplA):301A.
45.
Bahrani-Mougeot, FK, Paster B, Coleman S, Ashar J, Barbuto S, and Lockhart PB: Diverse and
Novel Oral Bacteria in Blood Following Dental Procedures. International Association of Dental
Research. March 2007. New Orleans. USA.
46.
Coleman S, Mougeot JC, Lockhart PB, and Bahrani-Mougeot FK: Assessment of bacteremia
following dental extraction and tooth brushing using quantitative real-time PCR. American Society
for Microbiology Annual Meeting. May 2007. Toronto, Canada.
18
47.
Brennan MT, Coleman S, Kent ML, Lockhart PB, Bahrani-Mougeot FK and Mougeot J-L. Gene
Expression Profiling of Buccal Mucosa Specimens from Patients with Acute Myelogenous Leukemia
Exposed to Chemotherapy. Annual Conference on Supportive Care in Cancer. June 2007 St Gallen,
Switzerland.
48.
Mougeot J-L, Bahrani-Mougeot FK, Castillos L, Lobenhofer EK, Brennan MT, Hurban P and
Lockhart PB. Molecular mechanisms of oral mucositis: High throughput systems biology analysis of
unique archival oral mucosal necropsy samples following cancer chemotherapy. Annual Conference
on Supportive Care in Cancer. June 2007 St Gallen, Switzerland.
49.
Napeñas JJ, Brennan MT, Kent ML, Noll J, Coleman S, Frenette G, Fox PC, Mougeot JL, Paster BJ,
Lockhart PB, Bahrani-Mougeot F. Alteration in the profile of oral flora following chemotherapy in
cancer patients. American Academy of Oral Medicine Annual Meeting. April 2008 Scottsdale,
Arizona.
50.
Thornhill M., Dayer M., Forde J.M., Corey G.R., Chu V.H., Couper D.J. and Lockhart P.B. Stopping
dental antibiotic prophylaxis didn’t increase UK infective endocarditis incidence. International
Association for Dental Research (IADR), Barcelona, 14-17th July 2010.
51.
M.H., Dayer M., Forde J.M., Corey G.R., Couper D.J. and Lockhart P.B. (2010) Cessation of
antibiotic prophylaxis for dental procedures and its effect on the incidence of infective endocarditis
in the UK. (Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting,
organised by the American Society for Microbiology (ASM), Boston, 12th – 15th Sept 2010). NOTE:
This abstract picked out by program committee to highlight to the pressroom at the meeting.
52.
Dayer M., Thornhill M.H., Forde J.M., Corey G.R., Chu V.H., Couper D.J. and Lockhart P.B. (2010)
No significant increase in the incidence of infective endocarditis following the cessation of antibiotic
prophylaxis for dental procedures. (European Society for Cardiology annual congress, Stockholm,
28th Aug – 1st Sept 2010). Note: Data also presented by Rosenhek (abstract 5252 + Webcast
http://assets.escardio.org/webcasts/default.aspx?id=ESC2010/5252 ) at the end of the ECS meeting
in a session identifying the meeting highlights. Also presented as part of a keynote lecture by
Bernard Prendergast “Endocarditis and what is new in the guidelines – prevention and patient
education (abstract 1148 + Webcast
http://assets.escardio.org/webcasts/default.aspx?id=ESC2010/1148 ).
53.
Karen’s AAOM abstract
54.
Dayer MJ, Pasquali SK, Cohen-Wolkowiez M, Thornhill MH, Couper D, Forde JM, Lockhart PB, Li
JS. The Impact of Cessation of Antibiotic Prophylaxis for the Prevention of Infective Endocarditis
in Children: A Population-Based Study in England. American Heart Association Annual Meeting,
Orlando, 2011.
55.
Hasan I, Lamb A, Brennan M, Lockhart PB. Oral Bacterial Pathogens as a Cause of Catheter-related
Infection. Oral Surg Oral Med Oral Pathol Oral Radiol, 2012.
SELECTED PRESENTATIONS:
Histologic changes of the oral mucosa in patients following cancer chemotherapy. Grand Rounds,
Department of Surgery, Brigham and Women's Hospital, Boston, 1981.
19
Oral manifestations of systemic disease. Introduction to Clinical Medicine Lecture Series, Harvard Medical
School, Boston, Annually 1981-1987.
Oral medicine: Recognition of normal from abnormal findings. Introduction to Clinical Medicine Lecture
Series, Harvard Medical School, Boston, Annually 1981-1987.
Hospital based dental care for the cancer patient. Joint Symposium on Oral Complications of Cancer
Chemotherapy. Baltimore, 1981.
Oral mucosal considerations in patients receiving cancer chemotherapy. Hematology Grand Rounds, Beth
Israel Hospital, Boston, 1982.
Dental considerations in medical practice. Introduction to Clinical Medicine Lecture Series, Harvard
Medical School, Boston, Annually 1982-1987.
Oral manifestations of hematologic disorders. Postdoctoral Graduate Students, Harvard School of Dental
Medicine, Boston, Annually 1982-1985.
Medical history taking for the dental practitioner. American Association of Hospital Dentists Regional
Meeting, Boston, 1983.
Odontogenic infections. Medical Resident Lecture Series, Department of Medicine, Brigham and Women's
Hospital, Boston, 1983.
Oral considerations in the practice of Infectious Disease. Infectious Disease Combined Grand Rounds, Beth
Israel/Brigham and Women's Hospitals, Boston, 1983.
Computerization of clinical research data on head and neck radiotherapy patients. Society of Oral Oncology
Annual Meeting, Boston, 1983.
Oral complications of cancer chemotherapy. Combined Tufts/Boston University Medical Grand Rounds,
Boston, 1983.
Diagnosis and management of oral soft tissue diseases. Harvard School of Public Health, Boston, 1985.
Oral mucosal problems for physicians. Department of Emergency Medicine, Carolinas Medical Center,
Charlotte, 1987.
Oral complications of cancer chemotherapy. Department of Dentistry, North Carolina Memorial Hospital,
Chapel Hill, 1988.
Odontogenic problems in the emergency room setting. Department of Emergency Medicine, Carolinas
Medical Center, Charlotte, 1988.
Dental management considerations in HIV+ patients. Symposium on dental practice considerations for
HIV+ patients. Carolinas Medical Center, Charlotte, 1988.
Relationship between pretreatment dental needs and tumor staging in patients receiving multimodality
therapy for head and neck cancer. Dental Grand Rounds, Department of Dentistry, Beth Israel Hospital,
New York, 1988.
20
Clinical Case Presentation, Special Guest Seminar. Department of Oral Diagnosis, University of
Connecticut School of Dental Medicine, Farmington, 1989.
Management of extractions and the replacement of teeth in the irradiated head and neck cancer patient.
Consensus Panel Member: Oral Cancer- The Disease and its Management. Fifth Annual Meeting of The
Society for Oral Oncology, Orlando, 1990.
Clinical management in oral medicine. Visiting Lecturer, Department of Oral Medicine, University of
Washington, Seattle, 1990.
Oral sequelae of endotracheal intubation, Department of Anesthesia Grand Rounds, Carolinas Medical
Center, Charlotte, 1990.
Oral manifestations of systemic disease – Parts 1&2, Department of Family Practice, Carolinas Medical
Center, Charlotte, 1990.
Cancer Therapies, Burrows Welcome Symposium-Updates of Medicine in Dentistry. American Association
of Hospital Dentists 3rd Annual National Conference, Chicago, 1991.
Oral manifestations of HIV disease. Charlotte Area Health Education Center Regional HIV/AIDS
Consortium, Charlotte, 1992.
Dentoalveolar trauma considerations for the plastic surgeon. Department of Plastic Surgery, Presbyterian
Hospital, Charlotte, 1992.
Endodontic considerations in the management of medically compromised patients. Department of
Endodontics, University of Pennsylvania School of Dental Medicine, Philadelphia, 1992.
The mouth: A mirror of systemic disease. Charlotte Postgraduate Seminar, Mecklenburg County Chapter
American Academy of Family Physicians, Charlotte, NC, 1993.
Oral manifestations of cancer chemotherapy. Department of Oral Medicine and Oral Microbiology, Guy's
Hospital, London, England, 1994.
Dental management considerations for patients receiving head and neck radiotherapy. Course: Dental Care
for the Handicapped, Glasgow Dental Hospital and School, Glasgow, Scotland, 1994.
The role of immunosuppression on complications following dental extractions. Third International Workshop
on the Oral Manifestations of HIV Infection, at The Royal College of Physicians, London, UK, 1996.
Bacteremia from invasive procedures and consequences for certain patient populations. University of
Glasgow Dental Hospital and School, Glasgow, Scotland, UK, 1997.
Dental management of the medically compromised patient. Dublin Dental Hospital, Dublin, Ireland, 1997.
Does dental bacteremia ever do any harm? 15th TC White Symposium - Controversies in the Dental Care of
the Medically Compromised. Royal College of Physicians and Surgeons of Glasgow, Glasgow, UK, 1998.
Hospital-based dentistry in the USA. Turner and Newell Lecture. University of Manchester, Turner Dental
21
School, Manchester, UK, 1998.
Dental management of the cancer patient. Supper Colloquium, Royal College of Physicians and Surgeons of
Glasgow, Glasgow, UK, 1998.
Dental bacteremia, reasons for concern. Dundee Dental Hospital, Dundee, UK, 1998.
Local anesthetic injections. Department of Emergency Medicine, Carolinas Medical Center, Charlotte, 1998.
Recognizing normal from abnormal oral mucosa. Department of Family Practice Medicine, Carolinas
Medical Center, Charlotte, 1998.
Bacteremia and distant site infection. Cannon Research Seminar Series, Carolinas Medical Center,
Charlotte, 1999.
Bacteremia from an oral source: Risks for systemic complications. Top 10 myths at the interface of
medicine and dentistry. Common oral/dental problems encountered in family practice. Carolinas
HealthCare System Spring Symposium, Charlotte Convention Center, Charlotte, 1999.
Oral manifestations of systemic disease and systemic manifestation of oral disease. 12th Annual Special
Care Conference, Chicago, March 2000.
History taking: Identification of the special needs patient. Bacteremia and distant site infection.
Management of patients with acquired coagulopathies. Royal College of Surgeons of Edinburgh, Scotland,
September 2000.
Oral manifestations of systemic disease vs systemic manifestations of oral disease. Forsyth Dental Institute,
Boston, MA, June 2001.
Bacteremia and distant site infection. Dublin Dental Hospital, Dublin, Ireland, 2002.
Bacteremia following dental procedures. 7th International Symposium on Modern Concepts in Endocarditis
and Cardiovascular Infections, Chamonix, France, June 2003.
Dental bacteremia: Cause for concern? General Surgery Research Conference, Carolinas Medical Center,
Charlotte, NC, 2004.
Dental bacteremia: Cause for concern? Oral Medicine Conference, New York University, June 2004.
The Case for Antibiotic Prophylaxis: Controversies in Bacteremia and Cardiovascular Infections. 8th
International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections, Charleston,
SC, May 2005.
Updates in Medicine – Antibiotic Prophylaxis. 18th Annual Meeting on Special Care Dentistry, Chicago, IL,
2006.
Samual Charles Miller Award Lecture – Antibiotic Prophylaxis. Annual Meeting of the American Academy
of Oral Medicine, Puerto Rico, 2006.
Myths at the Interface of Medicine and Dentistry. Department of Dentistry, Wake Forest University School
22
of Medicine. Wrightsville Beach, NC, 2006.
Bacteremia and Distant Site Infections. Glasgow Dental School, Glasgow, UK, 2006.
Endocarditis and Antibiotic Prophylaxis. Sanger Cardiology Grand Rounds, Carolinas Medical Center,
Charlotte, NC, 2007.
Endocarditis and the New American Heart Association Guidelines, Sanger Cardiology, Carolinas Medical
Center, Charlotte, NC, 2008.
Dental Bacteremia – Incidence, Nature, Duration and Magnitude. General Surgery Research Conference,
Carolinas Medical Center, Charlotte, NC, 2008.
Ventilator Associated Pneumonia (VAP), Special Care Dentistry Association’s Annual Conference, San
Antonio, TX, 2008.
Antibiotic Guidelines - Medical Guidelines Symposium, Special Care Dentistry Association’s Annual
Conference, San Antonio, TX, 2008.
Dental Procedures and the Risk of Subsequent Prosthetic Joint Infection: What is the data? 18th Annual
Open Scientific Meeting. MusculoSkeletal Infection Society, Lake Tahoe, CA, 2008
Oral Mucositis in Cancer Care – The End is in Sight. Royal College of Physicians and Surgeons Triennial
Conference, Glasgow, UK, 2008.
I have Mouth Cancer – To Whom should I be Referred. TC White Lecture - Royal College of Physicians and
Surgeons Triennial Conference, Glasgow, UK, 2008.
What is the Bacteremia Risk Associated with Activities of Daily Living? The combined 48th Annual
ICAAC (Interscience Conference on Antimicrobial Agents & Chemotherapy) - IDSA (Infectious Diseases
Society of America) 46th Annual Meeting, Washington, 2008
Antibiotic Prophylaxis in Dental Practice – A Re-evaluation. Max Bramer Lecture - Special Care Dentistry
Association’s Annual Conference, Baltimore, MD, 2009.
Oral Mucosal Infections in High-Dose Chemotherapy Patients - Clinical Management: Successes and
Barriers (bacterial), Oral Complications of Emerging Cancer Therapies Conference, Bethesda, MD, 2009.
Dental Health During Cancer Treatment. Oncology Nursing Society Annual Congress, San Antonio, TX,
2009.
What Should we do to Prevent Infective Endocarditis? 26th International Congress of Chemotherapy and
Infection, Toronto, Canada, 2009.
Antibiotic Prophylaxis – Dogma versus Data. Oral Health Sciences Seminar Series, University of Michigan
Dental School, Ann Arbor, MI, 2009.
The Role of Oral Medicine in the United States. 55th Congress of the Japanese Society of Maxillofacial
Surgery, Chiba, Japan. 2010.
23
Theoretical and Scientific Background of 2007 AHA Guidelines. Kanagawa Children's Medical Center,
Yokohama, Japan, 2010.
Dental Bacteremia and Distant Site Infections, Hokkaido University, Hokkaido, Japan, 2010.
Antibiotic Prophylaxis – A Re-Evaluation. Tokyo Dental College Ichikawa General Hospital, Tokyo, Japan,
2010.
Update on Antibiotic Prophylaxis for Patients Felt to be a t Risk for Endocarditis or Prosthetic Joint
Infections. The World of Oral Medicine, American Academy of Oral Medicine Annual fall meeting,
Philadelphia, 2010.
Antibiotic Prophylaxis for Prosthetic Joints American Academy of Oral Medicine Annual Meeting, Puerto
Rico, 2011.
Periodontal Disease and Cardiovascular Risk. American Academy of Oral Medicine Annual Meeting,
Charleston, SC, 2012.
Controversies at the Interface of Dentistry and Cardiology. 17th International Symposium on Endodontic
Biology: Systemic Considerations in Dental Patient Care. Avon, CT, 2012.
24

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