Next Generation Medicine?

Next Generation Medicine?
Ethical, Legal and technological questions of genomic high throughput
sequencing in the clinic
Date
November 14-15 2016
Venue
University Medical Center Goettingen, Lecture Hall MED 25
Von-Siebold-Straße 3, 37075 Goettingen
Organized by
the GenoPerspektiv Consortium
Ulrich Sax, PhD, Nadine Umbach, PhD,
Department of Medical Informatics, University Medical Center Goettingen
Due to increasingly effective technological platforms, sequencing of the human genome is now possible
within hours and for less than 1000 Euro. This development has sparked growing interest among clinicians
and molecular biologists. Genomic high throughput technologies are frequently hailed as a revolutionary
tool that will radically change clinical practice and establish “predictive”, “individualized” or “precision”
medicine. The aim is to target rare, clinically unrecognizable diseases or to subtype clinically
indistinguishable disorders with a suspected genetic background, e.g., in the oncological context. More
and more doctors, patients, and stakeholders are becoming aware of the possibilities of biomarker-based
high-throughput analyses.
At the same time, the clinical implementation of the rapid technological advances in the field of genomic
high throughput sequencing is accompanied by practical difficulties and uncertainties. The interpretation
and reporting of genomic findings in clinical practice, e.g., in molecular tumor boards, becomes more
complicated. The increasing volume of huge and highly complex data sets also poses problems regarding
sustainable infrastructures for management, integration and exploration of genomic sequencing data with
other clinical data. And finally, the large pool of sensitive and ambiguous data raises ethical, legal, and
social questions that are still in need of clarification, especially regarding informed consent, disclosure
policies, and data protection.
The workshop brings together experts from the fields of medicine, ethics, social sciences, law, and
biomedical informatics. The aim is an interdisciplinary discussion of the challenges posed by clinical
applications of genomic high throughput sequencing.
The keynote lecture will be given by Christian Lenk (Ulm), patient representatives will discuss about their
role and their position in next generation medicine.
We are looking forward to vivid discussions with you!
Further information on www.genoperspektiv.de or contact [email protected]
Next Generation Medicine?
Ethical, Legal and Technological Questions of Genomic
High- Throughput Sequencing in the Clinic
GenoPerspektiv Symposium
November 14 – 15, 2016
Hörsaal MED25, von-Siebold-Str. 3, 37075 Göttingen
Registration: [email protected]
Day 1
Time
Speaker
12:00
Title
Registration
12:30
Ulrich Sax,
Göttingen
Welcome
13:00
Christoph Schickhardt,
Heidelberg
Normative Challenges of Genomic HighThroughput in the Clinic
13:45
Benedikt Brors,
Heidelberg
Bioinformatics Approaches for the Molecular
Tumor Board
14:30
Coffee Break & Guided Poster Session
15:15
Martin Langanke,
Greifswald
The Role of Genetics in Systems Medicine
15:45
Matthieu-P. Schapranow,
Potsdam
Analyze Genomes: A Federated In-Memory
Computing Platform Enabling High-Throughput
Genome Data Analysis
16:15
Coffee Break & Guided Poster Session
17:00
Christian Lenk,
Ulm
18:00
Reception
Data, Body Material and the Person – Searching
for common ground in the international
regulation of genomic research
Day 2
Time
Speaker
Title
09:00
Thomas Wienker,
Berlin
Genomic High-Throughput in the
Clinic: Challenges and Perspectives
09:30
Ulrich M. Gassner,
Augsburg
Die datenschutzrechtliche Einwilligung in
genomische Hochdurchsatztechnologien
10:00
Coffee Break
10:20
Nadine Umbach / Ulrich Sax,
Göttingen
Infrastrukturen für die Nutzung von Daten aus
genomischen Hochdurchsatztechnologien
10:40
Julia Perera Bel / Tim Beissbarth,
Göttingen
How to Report Genomic High-Throughput Data
in Molecular Tumor Boards
11:00
Alexander Urban / Mark Schweda,
Göttingen
Zum Nutzen genomischer
Hochdurchsatztechnologien in der Klinik:
Perspektiven von Experten und Betroffenen
11:20
Laura Flatau / Thomas G. Schulze,
München & Göttingen
Neue Möglichkeiten in der Medizin –
Entscheidungen treffen! Eine Umfrage zu
Einstellungen, Erwartungen und Befürchtungen
der Bevölkerung gegenüber genomischen
Hochdurchsatzdaten
11:40
Gunnar Duttge,
Göttingen
Die ärztliche Schweigepflicht in Zeiten von Big
Data
12:00
Lunch Break
13:00
Patrick Schloss,
Mannheim
Ohne Darmspiegelung wäre ich nicht mehr am
Leben.
Sowie: Darmkrebs – was kommt danach?
Folgen für Betroffene und Angehörige
13:30
Martin Kolbe,
DGBS
Genomsequenzierung – wie denken Patienten
und Angehörige darüber?
14:00
Ulrich Sax
Göttingen
Concluding remarks

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