IMPROCUSH-2 Improving Outcome of Cushing`s Syndrome

Invitation
Martin Reincke, Felix Beuschlein, Medizinische Klinik und
Poliklinik IV, Ludwig-Maximilians University Munich
Dear colleagues,
Program Organizing Committee
Cushing’s syndrome has remained a diagnostic and
therapeutic challenge since its first description by
Harvey Cushing in 1912. Over the last decade, the
treatment of Cushing’s syndrome has made progress.
Surgical procedures have been refined and new
medical treatments have reached the market. Despite
these advances Cushing’s syndrome is a dreadful
disease causing many co-morbidities and premature
death if untreated. In addition, clinical problems
remain unsolved, such as early diagnosis or the need
for specific treatment of co-morbidities. This
symposium, therefore, aims to address some of these
issues by gathering leading experts in diagnosis and
treatment of Cushing’s syndrome.
Jerome Bertherat, Felix Beuschlein, Martin Reincke, Marily
Theodoropoulou
More recently also the understanding of genetics and
pathophysiology of Cushing’s syndrome has made
significant progress. Whether this will have impact on
the treatment cannot be decided at this stage.
However, the symposium will address this question by
reflecting some of the more recent advances.
Contact for free Communications
Sandra Schwaiger, phone +49-89-440057544
[email protected]
Registration
Registration is mandatory (email):
Sandra Schwaiger, fax. +49-89-440054428;
[email protected]
No registration fee. Beverages and meals will be provided
during the symposium.
Venue
Carl Friedrich von Siemens Stiftung
Südliches Schlossrondell 23; 80638 München
Klinikum der Ludwig-Maximilians-Universität
Medizinische Klinik, Campus Innenstadt
in cooperation with
The symposion is jointly sponsored by the Deutsche
Forschungsgemeinschaft and the Carl Friedrich von
Siemens Stiftung. We cordially invite you and would
be glad if you participate in this prime scientific event.
How to get there
Local Organising Committee
June 23 rd – 24th 2016
Munich, Carl Friedrich von
Siemens Stiftung
Südliches Schlossrondell
After the first successful meeting IMPROCUS-2
(Improving Outcome of Cushing’s Syndrome) in
October 2014 we are happy to announce the second
symposion of this kind. IMPROCUS-2 will be based
on an international faculty with experts from around
the world. Investigators will have the opportunity to
present their most recent data as short orals or as
posters. Plenty of time is reserved for discussion.
on behalf of the organizer
IMPROCUSH-2
Improving
Outcome of
Cushing’s
Syndrome
Tram 17 direction Amalienburgstrasse
Stop: Schloss Nymphenburg
Sektion Nebenniere, Steroide, Bluthochdruck
AG Hypophyse
European Network for the Study of Adrenal
Tumors (ENSAT)
Deutsche Forschungsgemeinschaft
Carl Friedrich von Siemens Stiftung
16.25
rd
Programme Thursday, June 23 2016
16.50
08.30
08.40
09.05
09.30
09.55
10:20
11.00
11.25
11.50
12.15
12.40
14.00
15:15
16.00
Session I Pathophysiology of CS
Welcome and Introduction
Martin Reincke, München
Regulation of POMC expression
Jacques Drouin, Montreal, Canada
USP8 in Cushing’s disease and Nelson’s
tumor
Marily Theodoropoulou, Munich
Glucocorticoid action
Henriette Uhlenhaut, Munich, Germany
Genetic factors and cortisol secretion
in normal subjects
Brian Walker, Edinburg, UK
Coffee Break
Session II Pathophysiology of CS
Chairs: Ronchi&Stalla
Connshing – a new syndrome
Wiebke Arlt, Birmingham , UK
Metabolomics in Cushing’s
Guido Di Dalmazi, Munich, Germany
New genetic hits in adrenal Cushing’s
Christina Ronchi , Würzburg, Germany
Neuropsychiatric disorders in
Cushing's syndrome
Anna Maria Colao, Naples, Turin
Lunch and Poster Viewing
Session III Free Communications from
all fields of CS
Chairs: NN
Coffee Break
Session IV Diagnosis and Subtyping
Chairs: Beuschlein&Arlt
Diagnostic score in Cushing’s
syndrome
17.10
17.35
18.00
19.30
N.N.
The plasma steroid metabolome in
Cushing’s Syndrome
Graeme Eisenhofer, Dresden
Progressive corticotroph tumor
Guillaume Assie, Paris, France
Conventional and Nuclear Medicine
Imaging in Ectopic Cushing's Syndrome
Rosario Pivonello, Naples, Italy
Ectopic Cushing’s syndrome: the use of
hair cortisol
Elisabeth van Rossum, Rotterdam, NL
Cushing’s syndrome in children
Constantine Stratakis, Bethesda, US
Dinner
Programme Friday, June 24th 2016
08.30
08.55
09.20
09.45
10:10
10.55
11.20
Session V Treatment
CRH and high dose dexamethasone
testing in subtyping of Cushing’s
syndrome
Katrin Ritzel, Munich, Germany
ARMC5
Jerome Bertherat, Paris, France
Unilateral adrenalectomy in primary
bilateral macronodular adrenal
hyperplasia
Olivier Chabre, Grenoble, France
Recovery of HPA axis and adrenal
crisis after successful treatment
Christina Berr, Munich, Germany
Coffee Break
Session VI Treatment
Chairs: Grossman&Theodoropoulou
Pasireotide
Monica Gadelha, Sao Paolo, Brasil
Metyrapone and osilodrostat
11.45
12.10
13:00
14.15
14.40
15.05
15.30
16.00
16. 25
16.50
18.00
John Newell-Price, Sheffield, UK
Novel tumor-targeted pharmaceuticals
in Cushing's diseas'
Günter Stalla, Munich, Germany
Cooperative Studies
Chair: Martin Reincke
Lunch and Poster Viewing
Session VII Surgery in CS
Chairs: Buchfelder&Swearingen
Optimal treatment algorithm
Ashley Grossman, Oxford, UK
Pituitary imaging
NN
Nondiagnostic SPI Catheter
Brook Swearingen, Boston, USA
Coffee Break
How do deal with
recurrence/persistence: the
neurosurgical perspective
Jürgen Honegger, Tübingen, Germany
Radiosurgery
Michael Buchfelder, Erlangen, Germany
Perioperative management during
transsphenoidal surgery for CD
Marcus Quinkler, Berlin, Germany
Session VI Late Breaking News in
Cushing’s syndrome
End of Program

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