Curriculum Vitae Jörg Hartkamp, Ph.D. Junior Group Leader at the Institute of Biochemistry and Molecular Biology Medical School RWTH Aachen University Education 02/1997-01/2002 Ph.D. thesis: ‘Regulation of MAPK signal cascades through the serine/threonine kinase MLK3’. Institut für Medizinische Strahlenkunde und Zellforschung (MSZ) (Prof. Ulf R. Rapp), Bayerische Julius Maximilians-Universität Würzburg, Germany 02/1996-01/1997 Diploma thesis: ‘Activation and regulation of the serine/threonine kinase MLK3’. Institut für Medizinische Strahlenkunde und Zellforschung (MSZ) (Prof. Ulf R. Rapp), Bayerische Julius Maximilians-Universität Würzburg, Germany 11/1991-02/1996 Study of Biology, Bayerische Julius Maximilians-Universität Würzburg, Germany Professional experience Since 09/2011 Junior Group leader at the Institute for Biochemistry and Molecular Biology, RWTH Aachen University, Germany (Prof. Bernhard Lüscher) 01/2003-08/2010 Postdoctoral Research Associate at the University of Manchester, Department of Life Sciences, UK (Dr. Stefan Roberts) 09/2001-08/2002 Postdoctoral Research Associate at the CRC Centre for Cell and Molecular Biology, Institute for Cancer Research, London, UK (Dr. Richard Lamb) Bibliography 1. Hartkamp, J. (2011). Opposing functions for the Wilms’ tumor protein 1 (WT1) in tumorigenesis. Curr. Pediatr. Rev. 7, 316-320. 2. Hartkamp, J., and Roberts, S.G.E. (2010). HtrA2, taming the oncogenic activities of WT1. Cell Cycle 9, 2508-2514. 3. Hartkamp, J., Carpenter, B., and Roberts, S.G.E. (2010). The Wilms’ tumour suppressor protein WT1 is processed by the serine protease HtrA2/Omi. Mol. Cell 37, 159-171. 4. Hartkamp, J., and Roberts, S.G.E. (2009). The role of the Wilms’ tumoursuppressor protein WT1 in apoptosis. Biochem. Soc. Trans. 36, 629-631. 5. Jaeschke, A., Hartkamp, J., Saitoh, M., Roworth, W., Nobukuni, T., Hodges, A., Sampson, J., Thomas, G., and Lamb, R. (2002). TSC tumor suppressor mediated S6 kinase inhibition by PI3k is mTor independent. J. Cell Biol. 159, 217-224. 6. Offenhausser, M., Herr A., Hartkamp, J., Wauben, M., Magnus, T., Grauer, O., Seubert, S., Weishaupt, A., Toyka, K., Gold, R., and Troppmair, J. (2002). Truncation of the neuritogenic peptide bP2(60-70) results in the generation of altered peptide ligands with the potential to interfere with T cell activation. J. Neuroimmunol. 129, 97-105. 7. Hartkamp, J., Troppmair, J., and Rapp, U.R. (1999). The JNK/SAPK activator mixed lineage kinase 3 (MLK3) transforms NIH 3T3 cells in a MEK-dependent fashion. Cancer Res. 59, 2195-2202. 8. Troppmair, J., Hartkamp, J., and Rapp, U.R. (1998). Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade. Oncogene 17, 685-690.
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