Deep Dive Understanding The New Normal Of A Digital Society Focus: Healthcare / Pharma Dr. Alexander Schachinger CEO, EPatient RSD GmbH, Berlin 80 years of stagnation in the healthcare systems mass media paradigm © facebook 2011 © 2015 E Patient RSD GmbH, Berlin 2 The New Normal © facebook 2011 © 2015 E Patient RSD GmbH, Berlin 3 Eine digitale Gesellschaft mit neuen sozialen und ökonomischen Paradigmen Vom proprietären zum Commons-Paradigma, vom Industrie- zum Informationsparadigma Yochai Benkler © 2015 E Patient RSD GmbH, Berlin Manuel Castells Jeremy Rifkin Clay Shirky Barry Wellman 4 Results of a bottom-up ecosystem within regulated top-down industries „“2,800 People with Acid Reflux Report Which Treatments Work Best” © 2015 E Patient RSD GmbH, Berlin 5 Wisdom Of The Patient Masses for Medical / Tech. Innovation © 2015 E Patient RSD GmbH, Berlin 6 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) © 2015 E Patient RSD GmbH, Berlin 7 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) 3 to 4 thousand health & medicine relevant websites, communities, apps © 2015 E Patient RSD GmbH, Berlin 8 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) 3 to 4 thousand health & medicine relevant websites, communities, apps © 2015 E Patient RSD GmbH, Berlin 9 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) Medical Internet Research & EPatient Science 3 to 4 thousand health & medicine relevant websites, communities, apps © 2015 E Patient RSD GmbH, Berlin 10 Medical Internet Research – a global evolving research field, most unknown in Central Europe and GER countries: Why? JOURNAL OF MEDICAL INTERNET RESEARCH Christensen et al Review in Internet Interventions for Anxiety and Depression: Adherence Systematic Review JOURNAL OF MEDICAL INTERNET RESEARCH Linn et al Helen Christensen, PhD, MPsych, BA; Kathleen M Griffiths, PhD, BSci; Louise Farrer, BPsych Review The Australian National University, Canberra, Australia Centre for Mental Health Research, Corresponding Author: Effects of eHealth Interventions on Medication Adherence: A Helen Christensen, PhD, MPsych, BA Systematic Review of the Literature Centre for Mental Health Research Australian National University Canberra ACT 0200 Australia Annemiek J Linn1, MSc; Marcia Vervloet2, MSc; Liset van Dijk2, PhD; Edith G Smit1, PhD; Julia CM Van Weert1, PhD Phone: +61 2 6125 8409 Fax: +61 2 6125 0733 1Amsterdam School of Communication Research, University of Amsterdam, Amsterdam, Netherlands 2 Netherlands Institute for Health Services Research, Utrecht, Netherlands Email: [email protected] Corresponding Author: Marcia Vervloet, MSc JOURNAL OF MEDICAL INTERNET RESEARCH Abstract Anhøj & Nielsen Netherlands Institute for Health Services Research P.O. Box 1568 Original Paper BN which deliver cognitive and behavioral interventions for anxiety and depression are Background: OpenUtrecht, access3500 websites JOURNAL OF MEDICAL INTERNET RESEARCH Netherlands characterised by poor adherence. We2729713 need to understand more about adherence in order to maximize the impact of Internet-based Phone: 31 30 Original Paper interventions on the disease associated with common mental disorders. Fax: 31burden 30 2729729 Email: [email protected] van Gaalen et al Quantitative and Qualitative Usage Data of an Internet-Based Asthma Monitoring Tool Objective: The aims of this paper are to review briefly the adherence literature with respect to Internet interventions and to Long-Term Outcomes of Internet-Based Self-Management Support investigate the rates dropout and, MA, compliance in randomized controlled trials of anxiety and depression Web studies. Jacob Anhøj , MD, DIT; of Lene Nielsen PhD Student Abstract in Adults Asthma: Methods: A systematic review of randomized controlled trials using Internet interventions for anxietyWith and depression was Randomized Controlled Trial AstraZeneca A/S, Business Communication, Albertslund, Denmark 1 2 1 2 Copenhagen Business of Informatics, Frederiksberg, Denmark Background: medication nonadherence is considered to be anand important risk, numerous conducted, andSchool, dataDepartment was collected onSince dropout and adherence, predictors of adherence, reasonshealth for dropout. interventions to improve adherence have been developed. During the past decade, the use of Internet-based interventions to improve medication adherence Corresponding Results: Author: Relative tohas reported rates of dropout open access sites, the present study foundL that the rates ofThijs attrition in and situation Johanna van MD; MD; Victor van der Meer, MD, PhD; Patricia van Reisen, MD; Geertje increased rapidly. Internet from interventions have the potential advantage of tailoring the Gaalen, interventions to theBeerthuizen, needs Jacob Anhøj, MD, DIT randomized controlled trials were lower, ranging from approximately 1 50%. Predictors of adherence included disease severity, W Redelijkheid, MD; Jiska B Snoeck-Stroband, MD, PhD; Jacob K Sont, PhD; SMASHING Study Group of the patient. AstraZeneca A/S Center, Department of Medical Decisionin Making, Leiden, Netherlands treatment length, and chronicity. few studies examinedreview reasons fortodropout, andLeiden mostUniversity studies failed to use appropriate Business Communication Objective:Very The main aim formally of this systematic was investigate which tailoredMedical Internet interventions are effective Roskildevej 22 improving medication adherence. statistical techniques to analyze missing data. Corresponding Author: DK-2620 Albertslund Jacob K Sont,EMBASE, PhD Methods: We undertook comprehensive literature searches in PubMed, PsycINFO, CINAHL, and Communication Conclusions: Dropout rates from randomized controlled trials of Web interventions are lowUniversity relative to dropout from open Denmark Leiden Medical Abstracts, following the guidelines of the Cochrane Collaboration. The methodological quality of theCenter randomized controlled trials Phone: +45 E 43666275 11 © 2015 PatientThe RSDdevelopment GmbH, Berlin of Medical Decision Making access websites. of theoretical models of adherence is as important in theDepartment area of Internet intervention research and clinical controlled trials and methods for measuring adherence were independently reviewed by two researchers. The Digital Healthcare Market in a Nutshell © 2015 E Patient RSD GmbH, Berlin 12 Global Scietific Best Practice Of Web-based Interventions © 2015 E Patient RSD GmbH, Berlin 13 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) Medical Internet Research & EPatient Science 3 to 4 thousand health & medicine relevant websites, communities, apps © 2015 E Patient RSD GmbH, Berlin 14 The Digital Healthcare Market in a Nutshell 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) Medical Internet Research & EPatient Science 3 to 4 thousand health & medicine relevant websites, communities, apps © 2015 E Patient RSD GmbH, Berlin 15 3. Results: Therapy: Medication: Effects of digital services in the focus of medication 10% I can understand my doctor's instructions concerning my medication much better now and follow it more easily. I changed the dosage or combination of my medication myself. 30% 34% I can handle my medication and the regular intake of it much better now. Because of my use of the internet or apps my doctor prescribed me a different kind of medication. 20% 40% ! 31% 14% 12% Base: n=2663 (all except interested parties, average value of "applies" and "partially applies" 0% Core result: It illustrates the potential of digital intervention for a therapy or medication adherence which so far has been applied or researched in a majorly unregulated, non-evaluated, structured way (concerning the first two items). In reverse, this dynamic also shows its effect on prescription and dosage behaviour of doctor and patient. EPatient Survey 2015 Data, Product License for (Customer) © 2015 E Patient RSD GmbH, Berlin 16 3. Results: Therapy: Medication: Desired source for receiving digital medication services 0% 20% 40% From my doctor 57% From my health insurance 38% I want to look for them myself online. Base: n=2663 (all except interested parties) 25% From a mail-order pharmacy From my hospital ! 28% From a patient organisation From the manufacturer of my medication 60% 19% 17% 8% Core result: In view of two so far separately existing "parallel worlds": traditional healthcare system with support structures and 40 million German "health browsers" online versus approx. 8000 healthcare websites, communities and apps, the question of how to merge these two worlds, becomes pressing. Answer items 1 and 2 might be pointing the way ahead. (Background: http://epatient-rsd.com/marktanalyse-digitaler-gesundheitsmarkt/ ) EPatient Survey 2015 Data, Product License for (Customer) © 2015 E Patient RSD GmbH, Berlin 17 3. Results: Therapy: Medication: Mentioned improvements/ideas for digital medication services 20% Understandability, Usability 39% Trusted Source, Transparence of Information Personalized Information on Medication Combination Effects 40% 19% 60% ! Base: n=1087 open text entries (summarized categories) 0% 17% Search, Compare on Similar Substances and Package Sizes 8% Every Day Life Best Practice on behalf my medication Intake (Sports, Food, Stress) 5% Personalized Information on Dosage and Intake 5% Key message. There is reason to suspect that a critical mass of services fail in their usability and comprehensibility and thus do not deliver their desired (therapeutic) effect. This aspect is a core area which clearly has not been examined enough in respects to its potential, although it bears effect potential (see examplatory: http://www.jmir.org/2012/6/e152/ ). The improvement of comprehensiveness and usability is ranking first place in all following therapy-specific ideas for improvement. EPatient Survey 2015 Data, Product License for (Customer) © 2015 E Patient RSD GmbH, Berlin 18 Results of a bottom-up ecosystem within regulated top-down industries „“2,800 People with Acid Reflux Report Which Treatments Work Best” 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) Medical Internet Research & EPatient Science New 3 to 4 thousand Generation Of health & medicine relevant Digital Health websites, communities, Startups apps © 2015 E Patient RSD GmbH, Berlin 19 Results of a bottom-up ecosystem within regulated top-down industries „“2,800 People with Acid Reflux Report Which Treatments Work Best” 40 Mio. Healthcare-surfers & epatients Traditional Healthcare System (1st Healthcare Market) Medical Internet Research & EPatient Science New 3 to 4 thousand Generation Of health & medicine relevant Digital Health websites, communities, Startups apps © 2015 E Patient RSD GmbH, Berlin 20 2. Der Gesamtmarkt Kommentar: Starke Reichweiten-‐ konzentraFon mit einem „Long Tail“ an vielen themaFsch differenzierten Webseiten mit kleineren Reichweiten. Reichweiten großer Publikumsportale wurden lediglich im Rahmen ihrer Gesundheitsinhalte berechnet. Fazit: Detailanalyse für IndikaFonen, Themen, Sonderzielgruppen für effekFve Mediaplanung sinnvoll. Basis: n= 11.880 Webseiten Alle Gesundheitswebseiten nach monatlicher Reichweite (Ausweisung immer in BruMo-‐Reichweiten) Besuche/Monat in Mio. 3,0# 2,5# 2,0# 1,5# 1,0# Top 400 0,5# 0,0# DGM REPORT DATA 2014 BASIS Dokumentlizenz für: Kundenname © 2014 EPaFent RSD GmbH, Berlin 11.880 Webseiten 13 Evolution of Health 2.0 Non Traditional Startups Entering The Traditional Healthcare Ecosystem © 2015 E Patient RSD GmbH, Berlin 22 Aufbau und Entwicklung DGM Report 2015 – Digitale Gesundheits-Startups Phase 1 2000–2008 (stationäres Internet) Entwicklung Unternehmen Anwendungen Phase 2 2008–20012 (Mobile Apps und erste neuen Dienste) Manuelle Datensammlung via App Fitness- / Bewegungs-Tracker Phase 3 2013–2015 Tracking via Wearables (1) X O Erste E-Learning Angebote Big Data Tracking / Echtweltdaten DATENSAMMLUNG / TRACKING Medizinisches Tracking (manuell + via Wearables) Individualisiertes Coaching (Information Therapy) (1) Coaching als Versicherungsleistung E-COACHING Tailored Coaching basierend individualisiertem Echtwelt-Feedback Digitale Apps Erste Versuche von OnlineGesundheitsakten Unabhängige Online Akte Vernetzte Online Akte PERSONAL HEALTH RECORD Webseiten, Portale, Communities, E-Commerce, Verzeichnisse Arzttermine Online Kleinere Daten/Anamnese Services Online Arztsprechstunde (1) ARZT-PATIENT-DIENSTE (LEISTUNGSERBRINGER) Arzt/Klinik Empfehlungen / Verzeichnisse Bottom-Up Bewertungsportale Erste Apps für Chroniker, Medikamente, Verlaufstagebücher, manuell (2) Erste SymptomChecker, DiagnoseApps, Risiko-Rechner Zweitmeinung MedikamentenManagement Daten-Management/ Apps für Medizingeräten Diagnostik basierend Angaben Fusion von Klinik-IT mit Patienten-Service auf Patienten-Smartphone (2) Medikamenten-App in Vernetzung mit Apothekenmarkt Digitale Adhärenz Forschung ANWENDUNGEN FÜR MEDIKAMENTE UND MEDIZINGERÄTE Mobile / Automatische Diagnostik INTERNETBASIERTE DIAGNOSTIK Laborbasierte Diagnostik Content und Community Tailored Content+Community Neue Formen von Infotainment / Aufklärung CONTENT + COMMUNITY Weisheit der Massen © 2015 E Patient RSD GmbH, Berlin 23 Case: Arya Smart Real World Data Transformed into Medicare Research Data and Outcome Research © 2015 E Patient RSD GmbH, Berlin 24 Case: Xbird.io 3rd Apps Smartphone Usage Converged Into Early Prevention And Early Sickness Patterns © 2015 E Patient RSD GmbH, Berlin 25 Case: Medisafe A virtual Pillbox including Reminders To Close Caregivers © 2015 E Patient RSD GmbH, Berlin 26 Evolution Of Basic Web-based Paradigms Therapy (evidence based) Tailored Information and Services Feedback Information © 2015 E Patient RSD GmbH, Berlin 27 Merci vielmals Dr. Alexander Schachinger Geschäftsführer, EPatient RSD GmbH, Berlin [email protected] © 2015 E Patient RSD GmbH, Berlin 28
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