氏名松本貴之所属医薬品化学研究所機能形態学研究

Hoshi University
氏
名
松本貴之
所
属
医薬品化学研究所
職
位
講師
機能形態学研究室
学
位
最終学歴
教育活動
（担当授業科目）
博士(薬学)
星薬科大学大学院薬学研究科博士後期課程中退
機能形態学 II
バイオスタティスティクス
薬学英語 IIB
生物系実習 II
研究活動
（研究テーマ）
所属学会
生活習慣病病態時における血管機能障害の解析
日本薬理学会、日本循環薬理学会、日本平滑筋学会、日本薬学会、日本糖尿病・肥満動
物学会、日本糖尿病学会、日本心脈管作動物質学会、The American Heart Association
(AHA)、The American Physiological Society (APS)、The American Society for
Pharmacology and Experimental Therapeutics (ASPET)、日本くすりと糖尿病学会
学内活動
（役職・委員等）
学生部委員会委員
高大連携委員会委員
認定薬剤師研修企画運営委員会委員
早期体験学習実施委員会委員
学外活動
（委員会委員等）
日本薬理学会学術評議員
Fellow of the American Heart Association (FAHA) (Council for High Blood Pressure
Research)
The Review of Diabetes Studies: Board of Reviewers
Conference Papers in Medicine: Editorial Board
Annals of Vascular Medicine and Research: Editorial Board
BioMed Research International: Editorial Board
研究業績等
（受賞歴）
2006 年平成 18 年度星薬科大学大谷記念研究助成金、 2006 年鈴木謙三記念財団法人医科学応用研究財団第
26 回(平成 18 年度)研究助成金、2007 年日本平滑筋学会第三回栗山熙賞、 2009 年平成 21 年度日本薬学会
関東支部奨励賞、 2009 年財団法人武田科学振興財団 2009 年度「薬学系研究奨励 (薬学)」、2009 年第 26 回
(2009 年度 ) 内藤記念海外研究留学助成金、 2010 年 The Harry Goldblatt New Investigator Award Finalist: The
American Heart Association, High Blood Pressure Council. 、2012 年 The 2012 International Early Career Physiologist
Travel Award: The American Physiological Society、2012 年公益財団法人三島海雲記念財団第 50 回研究奨励金、
2013 年第 55 回日本平滑筋学会総会優秀演題賞
（主な著書・論文）
1. MATSUMOTO, T., WATANABE, S., TAGUCHI, K. AND KOBAYASHI, T: Mechanisms underlying increased
serotonin-induced contraction in carotid arteries from chronic type 2 diabetic Goto -Kakizaki rats. Pharmacol.
Res, 87, 123-132 (2014)
2. MATSUMOTO, T., WATANABE, S., KAWAMURA, R., TAGUCHI, K. AND KOBAYASHI, T: Enhanced uridine
adenosine tetraphosphate-induced contraction in renal artery from type 2 diabetic Goto -Kakizaki rats due to
activated cyclooxygenase/thromboxane receptor axis. Pflugers. Arch, 466, 331-342 (2014)
3. GOULOPOULOU, S., HANNAN, J.L., MATSUMOTO, T., ERGUL, A. AND WEBB, R.C.: Augmented dilation to
nitric oxide in uterine arteries from rats with type 2 diabetes: impl ications for vascular adaptations to
pregnancy. Am. J. Physiol. Heart Circ. Physiol, 306:H610-618 (2014)
4. SPITLER, K.M., MATSUMOTO, T. AND WEBB, R.C.: Suppression of endoplasmic reticulum stress improves
endothelium-dependent contractile responses in aorta of the spontaneously hypertensive rat. Am. J. Physiol.
Heart Circ. Physiol, 305, H344-H353 (2013)
5. GOULOPOULOU, S., HANNAN, J.L., MATSUMOTO, T. AND WEBB, R.C.: Pregnancey reduces RhoA/Rho
kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat
uterine artery. Am. J. Physiol. Heart Circ. Physiol, 302, H2477-2488 (2012)
6. MATSUMOTO, T., SZASZ, T., TOSTES, R.C. AND WEBB, R.C.: Impaired -adrenoceptor-induced relaxation
in small mesenteric arteries from DOCA-salt hypertensive rats is due to reduced K(Ca) channel activity.
Pharmacol. Res, 65, 537-545 (2012)
7. MATSUMOTO, T., TOSTES, R.C. AND WEBB, R.C.: Alterations in vasoconstrictor responses to the
endothelium-derived contracting factor uridine adenosine tetraphosphate are region specific in DOCA -salt
hypertensive rats. Pharmacol. Res, 65, 81-90 (2012)
8. MATSUMOTO, T., TOSTES, R.C. AND WEBB, R.C.: Uridine adenosine tetraphosphate -induced contraction
is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats. Am. J. Physiol. Heart Circ.
Physiol, 301, H409-417 (2011)
9. MATSUMOTO, T., KOBAYASHI, T., ISHIDA, K., TAGUCHI, K. AND KAMATA, K.: Enhancement of mesenteric
artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2
diabetes. Br. J. Pharmacol, 160, 1092-1104 (2010)
10. MATSUMOTO, T., ISHIDA, K., NAKAYAMA, N., TAGUCHI, K, KOBAYASHI, T. AND KAMATA, K.:
Mechanisms underlying the losartan treatme nt-induced improvement in the endothelial dysfunction seen in
mesenteric arteries from type 2 diabetic rats. Pharmacol. Res, 62, 271 -281 (2010)
11. MATSUMOTO, T., NAKAYAMA, N., ISHIDA, K., KOBAYASHI, T. AND KAMATA, K.: Eicosapentaenoic acid
improves imbalance between vasodilator and vasoconstrictor actions of endothelium -derived factors in
mesenteric arteries from rats at chronic stage of type 2 diabetes. J. Pharmacol. Exp. Ther, 329, 324-334
(2009)
12. MATSUMOTO, T., NOGUCHI, E., ISHIDA, K., KOBAYASHI, T., YAMADA, N. AND KAMATA, K.: Metformin
normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF
rats, a model of type 2 diabetes. Am. J. Physiol. Heart Circ. Physiol, 295, H1165-1176 (2008)
13. MATSUMOTO, T., KAKAMI, M., NOGUCHI, E., KOBAYASHI, T. AND KAMATA, K.: Imbalance between
endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of
Type 2 diabetes. Am. J. Physiol. Heart Circ. Physiol, 293, H1480-1490 (2007)
14. MATSUMOTO, T., NOGUCHI, E., KOBAYASHI, T. AND KAMATA, K.: Mechanisms underlying the chronic
pioglitazone-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from
diabetic rats. Free Radic. Biol. Med, 42, 993-1007 (2007)
15. MATSUMOTO, T., KOBAYASHI, T. AND KAMATA, K.: Mechanisms underlying
lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long -Evans Tokushima
Fatty (OLETF) rat aorta. Br. J. Pharmacol, 149, 931-941 (2006)
16. MATSUMOTO, T., MIYAMORI, K., KOBAYASHI, T. AND KAMATA, K.: Apocynin normalizes hyperreactivity to
phenylephrine in mesenteric arteries from cholesterol -fed mice by improving endothelium-derived
hyperpolarizing factor response. Free Radic. Biol. Med, 41:1289-1303 (2006)
17. MATSUMOTO, T., KOBAYASHI, T., WACHI, H., SEYAMA, Y. AND KAMATA, K.: Vascular NAD(P)H oxidase
mediates endothelial dysfunction in basilar arteries from Otsuka Long -Evans Tokushima Fatty (OLETF) rats.
Atherosclerosis, 192:15-24 (2007)
18. MATSUMOTO, T., MIYAMORI, K., KOBAYASHI, T. AND KAMATA, K.: Specific impairment of
endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin -induced
diabetic mice. Vascul. Pharmacol, 44, 450-460 (2006)
19. MATSUMOTO, T., WAKABAYASHI, K., KOBAYASHI, T. AND KAMATA, K.: Diabetes -related changes in
cAMP-dependent protein kinase activity and decrease in relaxation response in rat mesenteric artery. Am. J.
Physiol. Heart Circ. Physiol, 287, H1064-1071 (2004)
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