ㄆ▱㻌 㻝㻭㻹㻜㻤㻠㻌 ᪥ᚰ➨ 㻣㻡 ᅇ䠄㻞㻜㻝㻝䠅㻌 ືࡢᙉᗘኚᑐࡍࡿ㇟㛵㐃㟁 ⸨ۑᮧ ⨾ 12࣭ᒸࣀ㇂ ୍ኵ 123 㸦 㸦⊂㸧⛉Ꮫᢏ⾡⯆ᶵᵓ ERATO ᒸࣀ㇂ືሗࣉࣟࢪ࢙ࢡࢺ࣭2㸦⊂㸧⌮Ꮫ◊✲ᡤ⬻⛉Ꮫ⥲ྜ◊✲ࢭࣥࢱ࣮࣭ 3 ᮾிᏛᏛ㝔⥲ྜᩥ◊✲⛉㸧 ࣮࣮࢟࣡ࢻ: ື㸪࣑ࢫ࣐ࢵࢳ㝜ᛶ㟁㸦MMN㸧㸪㇟㛵㐃⬻㟁㸦ERP㸧 1 Event-related potential elicited by intensity changes in emotional context Tomomi FUJIMURA12 and Kazuo OKANOYA123 1 ( JST ERATO Okanoya emotional information project, 2RIKEN BSI, 3 Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo) Key words: emotion, mismatch negativity (MMN), event-related potential (ERP) ⤖ ᯝ Oz ࡢ ERP ⥲ຍ⟬ᖹᆒἼᙧࢆᅗ 1 ♧ࡍࠋᛌ㸪ᛌ⣔ิ ࡶ㸪₯ 160 ms㸪240 ms㸪350 ms ㏆࡛㸪ᶆ‽่⃭ẚ㍑ ࡋ࡚㐓⬺่⃭ᑐࡍࡿ㝜ᛶᡂศࡀほᐹࡉࢀࡓࠋྛ᮲௳ࡢ Oz ࠾ࡅࡿ MMN ࡢ⥲ຍ⟬ᖹᆒࢆᅗ 2 ♧ࡍࠋศᩓศᯒࡢ⤖ᯝ㸪 140-180 ms ࡛ࡣ㸪ᙉᗘࡢຠᯝࡀ᭷ព࡛࠶ࡗࡓ(F(1,23)=5.90, p<.05)ࠋᙉᗘືࡢస⏝ࡶ᭷ព࡛࠶ࡾ(F(1,23)=11.06, p<.01)㸪ᛌ่⃭࠾࠸࡚ᙉ่⃭ࡣᙅ่⃭ࡼࡾࡶࡁ࡞ MMN ࢆច㉳ࡋࡓ(F(1,46)=16.43, p<.01)ࠋ220-260 ms ࡛ࡣᙉᗘࡢຠ ᯝࡢࡳ᭷ព࡛࠶ࡗࡓ(F(1,23)=18.70, p<.01)ࠋࡉࡽ 300-340 ms ࡛ࡣ㸪ᙉᗘࡢຠᯝ(F(1,23)=3.68, p<.10)࠾ࡼࡧᙉᗘືࡢ స⏝(F(1,23)=3.00, p<.10)ࡀ᭷ពഴྥ࡛࠶ࡗࡓࠋ -4 -4 Negative Sequence 0 0 2 2 ȝV -2 ȝV -2 Positive Sequence 4 4 Standard 6 Standard 6 Deviant_Strong 8 0 100 200 300 400 500 Deviant_Strong 8 Deviant_Weak 10 -100 600 10 -100 Deviant_Weak 0 100 200 300 400 500 600 Figure1. Grand averaged ERP wave forms from Oz Negative Positive Negative Positive Negative Positive 0 0 -0.5 -0.5 -0.5 -1 -1.5 -2 MMN(ȝ) 0 MMN(ȝ) MMN(ȝ) ┠ ⓗ ㇟㛵㐃⬻㟁(event-related potential: ERP)ࡢ୍ࡘ࡛࠶ࡿ࣑ ࢫ࣐ࢵࢳ㝜ᛶ㟁(mismatch negativity: MMN)ࡣ㸪่⃭⣔ิෆ ࠾ࡅࡿ≀⌮ⓗ࡞≉ᚩࡢኚࡼࡗ࡚⏕ࡌࡿ㝜ᛶᡂศ࡛࠶ࡿ ࡀ㸪ືⓗ࡞㐓⬺ᑐࡋ࡚ࡶច㉳ࡍࡿࡇࡀሗ࿌ࡉࢀ࡚࠸ࡿ (Astikainen & Hietanen, 2009)ࠋᮏ◊✲࡛ࡣ㸪ືⓗ MMN ࡀ ືࡢᙉᗘኚࢆࡶᫎࡍࡿࢆ᳨ウࡋࡓࠋ ᪉ ἲ ᐇ㦂ཧຍ⪅ ᡂே 27 ྡࡀᐇ㦂ཧຍࡋࡓࠋ࣮ࢸࣇ ࢡࢺࡢᙳ㡪ࡼࡾ 3 ྡࡢࢹ࣮ࢱࢆ㝖እࡋ㸪24 ྡ(⏨ᛶ 11 ྡ㸪 ዪᛶ 13 ྡ)ࢆศᯒᑐ㇟ࡋࡓࠋᖹᆒᖺ㱋ࡣ㸪25.3 ṓ(SD=4.1) ࡛࠶ࡗࡓࠋ ่⃭ ື่⃭ࡋ࡚₎Ꮠࢆ⏝ࡋࡓࠋ₎Ꮠࡢື౯ࡘ ࠸࡚ᛌ̺ᛌࡢホᐃ್(1-9)ࢆồࡵࡓணഛㄪᰝ⤖ᯝࡽ㸪ᶆ‽ ่⃭ࡋ࡚㸪ືⓗ୰ᛶ࡛࠶ࡿ 8 ࡘࡢ₎Ꮠࢆ⏝ࡋࡓ(ex. ⛬ 㸪 ⏬ )ࠋ㐓⬺่⃭ࡣ㸪ືᙉᗘࡢᙉ࠸ࡶࡢᙅ࠸ࡶࡢ ࢆタᐃࡋࡓࠋᛌ่⃭ࡣ ᮃ (M=2.5)㸪 ᰤ (M=3.1)㸪ᛌ่ ⃭ࡣ ẅ (M=7.5)㸪 ༴ (M=7.1)࡛࠶ࡗࡓࠋᛌ่⃭ᛌ่ ⃭ࡣ⊂❧ࡋࡓ⣔ิෆ࡛࿊♧ࡋࡓࠋࡍ࡚ⓑᆅ㯮Ꮠ࡛࿊♧ࡋ㸪 ㄢ㢟ࡢࢱ࣮ࢤࢵࢺ่⃭ࡋ࡚ྛ⣔ิࡢᶆ‽่⃭ྠࡌ₎Ꮠࢆ ⅊Ⰽ࡛࿊♧ࡋࡓࠋ่⃭ࡢࡁࡉࡣ㸪どゅࡋ࡚ᖜ 6.8°㧗ࡉ 7.2°࡛࠶ࡗࡓࠋ ᡭ⥆ࡁ ྛ⣔ิ࠾࠸࡚㸪ᶆ‽่⃭ࡋ࡚㸪ྠ୍ࡢ₎Ꮠࢆ 20 ᅇ࿊♧ࡋィ 160 ヨ⾜⾜ࡗࡓࠋ㐓⬺่⃭ࡣᙉ࣭ᙅ่⃭ࡶ 20 ヨ⾜㸪ࢱ࣮ࢤࢵࢺ่⃭ࡣྠ୍ࡢ₎Ꮠࢆ 2 ᅇ࿊♧ࡋィ 16 ヨ ⾜࡛࠶ࡗࡓࠋྛ⣔ิࢆ 4 ᅇ⧞ࡾ㏉ࡋ㸪ᛌࣈࣟࢵࢡᛌࣈࣟ ࢵࢡศࡅ࡚ᐇࡋࡓࠋࣈࣟࢵࢡࡢ⾜㡰ᗎࡣᐇ㦂ཧຍ⪅㛫 ࡛࢝࢘ࣥࢱ࣮ࣂࣛࣥࢫࢆࡗࡓࠋ่⃭ࡣࡍ࡚ 200 ms ࿊♧ࡋ㸪 ่⃭㛫㛫㝸ࡣ 800-1000 ms ࡛ኚࡉࡏࡓࠋᐇ㦂ཧຍ⪅ࡢㄢ㢟 ࡣ㸪㐃⥆ⓗ࿊♧ࡉࢀࡿ₎Ꮠࡢ୰࡛⅊Ⰽࡢࢱ࣮ࢤࢵࢺ่⃭ ᑐࡋ࡚࣮࢟ᢲࡋᛂࢆࡍࡿࡇ࡛࠶ࡗࡓࠋ ⬻Ἴグ㘓 ⬻Ἴࡣ㸪㖟࣭ሷ㖟㟁ᴟࢆ⏝࠸࡚ᅜ㝿 10-20 ἲ ᇶ࡙ࡁ 32 㒊ࡽ㰯ᑤࢆᇶ‽㟁ᴟࡋ࡚ᑟฟࡋࡓࠋ ࢹࢪࢱ ࣝ⬻Ἴィ㸦SynAmps, Neuroscan㸧ࢆ⏝࠸࡚ࢧࣥࣉࣜࣥࢢ࿘Ἴ ᩘ 500 Hz ࡛ A/D ኚࡋ㸪ࣂࣥࢻࣃࢫࣇࣝࢱ 0.15 Hz-30 Hz ࡛グ㘓ࡋࡓࠋ่⃭࿊♧๓ 100 ms ࡢᖹᆒᖜࢆ࣮࣋ࢫࣛࣥ ࡋ㸪่⃭࿊♧ᚋ 600 ms ࡲ࡛ࢆ᮲௳ࡈຍ⟬ᖹᆒࡋࡓࠋ ศᯒ ᚋ㢌㒊㸦Oz, O1, O2㸧ࢆศᯒᑐ㇟ࡋࡓࠋᶆ‽่ ⃭ࡣ㸪㐓⬺่⃭ࡢ 1 ࡘ๓࿊♧ࡉࢀࡓヨ⾜ࡢࡳࢆศᯒᑐ㇟ ࡋࡓࠋ㐓⬺่⃭ࡢຍ⟬ᖹᆒἼᙧࡽ㸪ᶆ‽่⃭ࡢຍ⟬ᖹᆒἼ ᙧࢆῶ⟬ࡋ㸪MMN ࢆ⟬ฟࡋࡓࠋMMN ࡀࡁࡃほᐹࡉࢀࡓ₯ 㸪140-180 ms㸪220-260 ms㸪330-370 ms ࡢᮇ㛫ࡘ࠸࡚㸪ྛ ่⃭ࡢᖹᆒᖜࢆ⟬ฟࡋࡓࠋࡇࢀࡽࡘ࠸࡚㸪ື౯(ᛌ࣭ ᛌ)ᙉᗘ(ᙉ࣭ᙅ)㒊(Oz, O1, O2)ࡢ 3 せᅉࡢ⿕㦂⪅ෆศᩓ ศᯒࢆ⾜ࡗࡓࠋ -1 -1.5 -2 -2.5 -2.5 140-180 ms -1 Strong -1.5 Weak -2 220-260 ms 330-370 ms Figure 2. Mean voltage amplitude of MMN with standard error bars from Oz ⪃ ᐹ ᮏ◊✲࡛ࡣ㸪ᶆ‽่⃭ࡋ࡚ືⓗ୰❧࡞₎Ꮠࢆࡑࢀࡒ ࢀ㐓⬺่⃭ྠᅇᩘ࿊♧ࡋࡓࠋࡋࡓࡀࡗ࡚㸪ほᐹࡉࢀࡓ MMN ࡣ㸪₎Ꮠࡢᙧែⓗ≉ᚩࡢ㐓⬺ࡼࡿࡶࡢ࡛ࡣ࡞ࡃືⓗ࡞㐓 ⬺ࡼࡗ࡚⏕ࡌࡓࡶࡢゎ㔘࡛ࡁࡿࠋࡇࡢື MMN 㛵ࡋ ࡚㸪ࡍ࡚ࡢᮇ㛫࠾࠸࡚ືᙉᗘࡀᙉ࠸่⃭ࡣᙅ࠸่⃭ ᑐࡋ࡚ࡼࡾࡶࡁ࡞ᖜࢆ♧ࡋࡓࠋࡇࢀࡣ MMN ࡀ่⃭ࡢ ືᙉᗘࢆᫎࡋ࡚࠸ࡿࡇࢆ♧ࡍࠋࡉࡽ㸪₯ 160 ms ࡛ࡍ ࡛ື MMN ࡀほᐹࡉࢀࡓࡇࡣ㸪ືⓗฎ⌮ࡀ㏻ᖖࡢព ฎ⌮ࡼࡾ᪩࠸ẁ㝵࡛⾜ࢃࢀࡓࡇࢆ♧၀ࡍࡿࠋ₯ 140-180 ms ࡛ࡣ㸪ᛌ่⃭࠾࠸࡚ࡢࡳᙉ࣭ᙅ่⃭㛫࡛ MMN ࡢᕪࡀࡳ ࡵࡽࢀࡓࠋᛌ่⃭࡛ࡣ㸪่⃭ᙉᗘ㛵ಀ࡞ࡃ⬣ጾಙྕ ࡋ࡚ࡢฎ⌮ࡀᐇ⾜ࡉࢀࡓࡓࡵ㸪ᙉ࣭ᙅ่⃭㛫࠾ࡅࡿ MMN ࡢᖜᕪࡀぢࡽࢀ࡞ࡗࡓࡢࡶࡋࢀ࡞࠸ࠋ ᘬ⏝ᩥ⊩ Askitainen, P., and Hietanen, J. K. (2009). Event-related potentials to task-irrelevant changes in facial expressions. Behavioral and brain Functions, 5:30. ̿ 592 ̿
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