ｾﾋ|ﾌｷﾂe ® ｾﾋY{ﾂﾋM ｽﾁ|ﾋﾁﾂa Tolidin® ( Povidone Iodine )

Tolidin®
( Povidone Iodine )
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Indications:
It is used as a disinfectant and antiseptic mainly for the treatment YÌ/ad/ÂaÉZ/Ã{Z/»MÁZÅºy½{¯Ê¿Â¨|ÉY]Ã{Z»¾ËY
of contaminated wounds and pre-operative preparation of the skin ½YÁ[Z/Æf·Y½Z»{ÉY]µZÀËYÁÉZÅÃ{ÁY§{ÁÊ»Z°]ÊuYmµZ¼Y
and mucous membranes. Vaginal products are used for relief of
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minor vaginal irritation, itching and soreness caused by candida
and trichomonas.
Classification:
Antiseptic, Disinfectant
Mechanism of Action:
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Povidone- iodine is a loose complex of iodine and carrier {YMª/ËYÁd/Y¶/»Zu½YÂ/ÀÄ/]ZÅ¼Ì¸aÁ|ËYÊ^Ì¯eÁY{¾ËY
polymers.It releases iodine to exert an effect against bacteria ( g+,
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g- ), Fungi, Viruses, Protozoa, Cysts and spores.
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Precautions:
-Use with caution in patients with history of hypersensitivity to
these types of products.
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- The application of povidone- iodine to severe burns or to large
areas may produce the systemic adverse effects.
d/Y¾/°¼»dÂaÌÁªZÀ»{ZË|Ë|ÉZÅÊ´fyÂ{Ã{Z¨fY- Use with caution in neonates, pregnants and breast feeding
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mothers.
{Â¥»ZÌfuYZ]Ê´¸»ZuÁÃ{Ì½Y{Z»Á½Y{YÂ¿{Contraindications:
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Regular or prolonged use should be avoided in patients with É|ÌWÁÌecÓÔfyYÄ]Ôf^»½YZ¼Ì]{ÁY{c|»Ê¿ÓÂZËºÀ»¥»
thyroid disorders or those receiving lithium therapy.
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Side/ Adverse effects:
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Local irritation,
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The application of povidone- Iodine to severe burns or to large
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dÂaÌÁ
areas may produce systemic adverse effects associated with iodine
such as metabolic acidosis, Hypernatraemia, Impairment of renal
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function.
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Usual doses:
- Apply adequet amount of solution for treatment of wounds and
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preoperative preparations.
{Ê/fuÄ/f¨Å-c|»Ä]\ÅÂeZ°Ì¸aY®ËµZÀËYÁµ{Â»{- Apply a full applicator every night for 2-4 weeks even during
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menstrual cycles.
Dosage forms:
Topical Solution 10% ( 4000,1000,250,60ml )
Surgical Scrub 7.5% ( 4000,1000,250ml )
Vaginal gel 10%
Refrences:
Martindale 35
PDR 53
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