Elsevier Editorial System(tm) for Journal of Ethnopharmacology Manuscript Draft Manuscript Number: Title: Ethnobotanical investigation on wild plants in the Monti Sicani Regional Park (Sicily, Italy) Article Type: Full Length Article Keywords: medicinal plants; Mediterranean; folk medicine; cultural erosion; ethnobotanical indexes Corresponding Author: Prof. Claudio Leto, M.D. Corresponding Author's Institution: University of Palermo First Author: Claudio Leto, M.D. Order of Authors: Claudio Leto, M.D.; Teresa Tuttolomondo, M.D., PhD; Salvatore La Bella, M.D., PhD; Giuseppe Bonsangue, M.D., PhD; Giuseppe Venturella, M.D.; Maria Letizia Gargano, M.D., PhD; Valentina Savo, M.D., PhD; Mario Licata, M.D., PhD Abstract: The area of the "Monte Sicani Regional Park" (Central Western Sicily, southern Italy) has been quantitatively and extensively investigated in an ethnobotanical study for the first time. A total of 108 wild species are used for medicinal purposes, while, according to our study, the uses of 9 species have not previously been reported in ethnobotanical studies in Italy. The aim of this paper is to analyze, through quantitative indicators, the extent of the current knowledge on medicinal uses of plants in the area, evaluating also the features of uniqueness and commonality of this knowledge in comparison with other Italian and Mediterranean areas. Semi-structured interviews were carried out in the local communities within the Monti Sicani Regional Park with local people retained experts in rural traditions. A total of 230 people were interviewed about their knowledge on medicinal plant uses. Local plant uses were evaluated using ethnobotanical indices (e.g., cultural importance index, ethnobotanicity index, informant consensus factor) and then compared with uses in other localities in Sicily, Italy and the Mediterranean basin. Local communities currently use a total number of 108 wild species (43 families) as remedies for human and livestock ailments. The majority of plants are used in the treatment of articular, skin and, gastrointestinal problems. The research shows an ongoing process of cultural erosion in an advanced stage, but results still highlight an interesting cultural identity as regards the local folk medicine. Cover Letter Cover letter Dear Editorial Board of Journal of Ethnopharmacology, Please find enclosed the manuscript: “Ethnobotanical investigation on wild plants in the Monti Sicani Regional Park (Sicily, Italy)”, by Claudio Leto, Teresa Tuttolomondo, Salvatore La Bella, Giuseppe Bonsangue, Giuseppe Venturella, Maria Letizia Gargano, Valentina Savo and Mario Licata, to be submitted as a new full length article to Journal of Ethnopharmacology. All co-authors have seen, read and agree with the contents of the manuscript and there is no financial interest to report. It has not been submitted for publication nor has it been published in whole or in part elsewhere. I attest to the validity and legitimacy of the data and its interpretation and I agree to its submission to the mentioned journal. I attest that the study was carried out following the ISE code of Ethics. Informants were made aware of the scope of the study and Prior Informed Consent was requested verbally. In this manuscript we report the results of an ethnobotanical study carried out in the Monti Sicani Regional Park (Central-Western Sicily, Italy) regarding the medicinal uses of wild plant species. A total of 108 wild species are used for medicinal purposes. The research shows an ongoing process of cultural erosion in an advanced stage, but results still highlight an interesting cultural identity as regards the local folk medicine. The majority of plants are used in the treatment of articular, skin and, gastrointestinal problems. We believe that our findings could be of interest to the readers of the Journal of Ethnopharmacology. The research examines, from an ethnobotanical and pharmacological point of view, an area that is famous for its biodiversity. A total of 850 vascular plants grow in the park and among these 68 (9.5%) are endemic. The comparison with other studies carried out in other Italian regions and Mediterranean countries has shown that the majority of the medicinal uses are common or similar to those reported in bibliography. Although some therapeutic uses seem to be "new" in literature, the highlighted cultural erosion could have already eliminated important pieces of the ethnobotanical knowledge of the study area. The investigation carried out in the Monti Sicani Regional Park represents a first quantitative and detailed contribution to the ethnobotanical exploration of the area. In the future it would be necessary to extend the research to the younger generations and including more women in order to better understand the complex processes of transmission of knowledge across generations and between genders We hope the editorial board will agree on the interest of this study. Sincerely yours, Claudio Leto on behalf of the authors. Corresponding author: Claudio Leto at Department of Agricultural and Forest Sciences, Università degli Studi di Palermo, Palermo, Italy, e-mail: [email protected], phone number: +3909123862223, fax number: +3909123862246 *Author Checklist Author checklist Dear Editorial Board of Journal of Ethnopharmacology, I attest that: a. the manuscript type is a full length research article; b. the manuscript is in the requested structured format (title, authors, full postal address, fax and e-mail address, abstract, keywords, introduction, materials and methods, results, discussion, conclusions, references, tables and figures, all figure and tables captions); c. the manuscript has been spell-checked and grammar-checked; d. the abstract is in the requested structured format; e. the references are cited and used in the right format; f. all references mentioned in the reference list are cited in the text and vice versa; g. the corresponding author’s postal address, telephone and fax numbers are complete on the manuscript; h. the corresponding author’s e-mail address is provided; i. the manuscript/data, or parts thereof, has not been submitted or published elsewhere for publication; j. the data are valid and legitimate; k. all the listed authors have read and approved the submitted manuscript; l. there is no financial interest to report in the manuscript; m. the study has been performed according to international, national and regional rules concerning ethnobotanical and pharmacological studies and biodiversity rights; n. informants were made aware of the scope of the study and Prior Informed Consent was requested verbally. Sincerely yours, Claudio Leto on behalf of the authors. Corresponding author: Claudio Leto at Department of Agricultural and Forest Sciences, Università degli Studi di Palermo, Palermo, Italy, e-mail: [email protected], phone number: +3909123862223, fax number: +3909123862246 *Graphical Abstract (for review) Click here to download high resolution image *Abstract Abstract 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Ethnobotanical investigation on wild plants in the Monti Sicani Regional Park (Sicily, Italy) Claudio Letoa*, Teresa Tuttolomondoa, Salvatore La Bellaa, Giuseppe Bonsanguea, Giuseppe Venturellaa, Maria Letizia Garganoa, Valentina Savob, Mario Licataa a Department of Agricultural and Forest Sciences, Università degli Studi di Palermo – Viale delle Scienze 13, 90128 Palermo, Italy E-mail: [email protected]: [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected] b Hakai Network for Coastal People, Ecosystems and Management, Simon Fraser University, 8888 University Drive, BC V5A 1S6, Burnaby, Canada E-mail: [email protected] *Corresponding author at Department of Agricultural and Forest Sciences, Università degli Studi di Palermo, Viale delle Scienze 13, 90128 Palermo, Italy Tel. : +3909123862223. Fax: +3909123862246. E-mail: [email protected] The authors contributed equally. Ethnopharmacological relevance: the area of the “Monte Sicani Regional Park” (Central Western Sicily, southern Italy) has been quantitatively and extensively investigated in an ethnobotanical study for the first time. A total of 108 wild species are used for medicinal purposes, while, according to our study, the uses of 9 species have not previously been reported in ethnobotanical studies in Italy. Aim of the study: the aim of this paper is to analyze, through quantitative indicators, the extent of the current knowledge on medicinal uses of plants in the area, evaluating also the features of uniqueness and commonality of this knowledge in comparison with other Italian and Mediterranean areas. Methodology: Semi-structured interviews were carried out in the local communities within the Monti Sicani Regional Park with local people retained experts in rural traditions. A total of 230 people were interviewed about their knowledge on medicinal plant uses. Local plant uses were evaluated using ethnobotanical indices (e.g., cultural importance index, ethnobotanicity index, informant consensus factor) and then compared with uses in other localities in Sicily, Italy and the Mediterranean basin. Results: Local communities currently use a total number of 108 wild species (43 families) as remedies for human and livestock ailments. The majority of plants are used in the treatment of articular, skin and, gastrointestinal problems. Conclusions: The research shows an ongoing process of cultural erosion in an advanced stage, but results still highlight an interesting cultural identity as regards the local folk medicine. *Manuscript Click here to view linked References 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 ETHNOBOTANICAL INVESTIGATION ON WILD PLANTS IN THE MONTI SICANI REGIONAL PARK (SICILY, ITALY) Claudio Letoa*, Teresa Tuttolomondoa, Salvatore La Bellaa, Giuseppe Bonsanguea, Giuseppe Venturellaa, Maria Letizia Garganoa, Valentina Savob, Mario Licataa a Department of Agricultural and Forest Sciences, Università degli Studi di Palermo – Viale delle Scienze 13, 90128 Palermo, Italy E-mail: [email protected]: [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected] b Hakai Network for Coastal People, Ecosystems and Management, Simon Fraser University, 8888 University Drive, BC V5A 1S6, Burnaby, Canada E-mail: [email protected] *Corresponding author at Department of Agricultural and Forest Sciences, Università degli Studi di Palermo, Viale delle Scienze 13, 90128 Palermo, Italy Tel. : +3909123862223. Fax: +3909123862246. E-mail: [email protected] The authors contributed equally. Abstract Ethnopharmacological relevance: the area of the ―Monte Sicani Regional Park‖ (Central Western Sicily, southern Italy) has been quantitatively and extensively investigated in an ethnobotanical study for the first time. A total of 108 wild species are used for medicinal purposes, while, according to our study, the uses of 9 species have not previously been reported in ethnobotanical studies in Italy. Aim of the study: the aim of this paper is to analyze, through quantitative indicators, the extent of the current knowledge on medicinal uses of plants in the area, evaluating also the features of uniqueness and commonality of this knowledge in comparison with other Italian and Mediterranean areas. Methodology: Semi-structured interviews were carried out in the local communities within the Monti Sicani Regional Park with local people retained experts in rural traditions. A total of 230 people were interviewed about their knowledge on medicinal plant uses. Local plant uses were evaluated using ethnobotanical indices (e.g., cultural importance index, ethnobotanicity index, informant consensus factor) and then compared with uses in other localities in Sicily, Italy and the Mediterranean basin. Results: Local communities currently use a total number of 108 wild species (43 families) as remedies for human and livestock ailments. The majority of plants are used in the treatment of articular, skin and, gastrointestinal problems. Conclusions: The research shows an ongoing process of cultural erosion in an advanced stage, but results still highlight an interesting cultural identity as regards the local folk medicine. Keywords: medicinal plants; Mediterranean; folk medicine; cultural erosion; ethnobotanical indexes 1. Introduction Sicily boasts a long tradition of ethnobotanical studies. The first ethnobotanical explorations probably date back to the XIV century (Pitrè, 1896; De Natale and Marziano, 2009), while the majority of studies are more recent (e.g., Lentini and Raimondo, 1990; Amico and Sorge, 1997; Napoli and Giglio, 2002; Lentini and Venza, 2007). The region has a rather high biodiversity [more than 3000 wild plants (Di Martino and Raimondo, 1979), of which 322 are endemic or sub endemic (Raimondo et al., 2010)] and a central position in the Mediterranean, privileged position for cross cultural exchanges and influences (Guarrera, 2009). According to a recent review, in the island around 300 plants are used for medicinal purposes in Sicily (Leonti et al., 2009), while many have 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 been analyzed for their phytochemical profile (e.g., Bellino et al., 1986; Napoli et al., 2009; Napoli et al., 2010; Caligiani et al., 2013). The historical events and the biodiversity of natural environment of Sicily have contributed to expand and differentiate the knowledge and traditions related to the use of the different plant species. An increasing number of people has rediscovered the importance of natural therapies based on plants (Pieroni et al., 2013a). This interest has been fueled by media and the spread of a ―green culture‖ which promotes the use of natural products and the need to reduce and/or replace products of synthesis. In contrast, in several remote areas, many traditional uses of plants have decreased or completely disappeared, due to the fast pace of economic globalization, which has promoted the replacement of plant materials which cheaper (synthetic) ones and has fostered the migration of rural populations to urban areas, with the adoption of new lifestyles. Despite the ongoing process of cultural erosion that is occurring in several areas in the Mediterranean (Quave et al., 2012), recent local studies are providing testimonies of well-preserved ethnobotanical practices (e.g., Vitalini et al., 2009; Mustafa et al., 2011; Gürdal and Kültür, 2013). This paper reports a comprehensive study on the medicinal use of plants and the related folk traditions in a natural area named Monti Sicani Regional Park (Central-Western Sicily). It investigates the medicinal uses of plants that are harvested in the different natural habitats of the area. Several researchers have lately questioned and discussed the value of ethnobotanical research in the Mediterranean, especially as regards plants used as medicinal (e.g., Leonti et al., 2010; Leonti, 2011). In this paper we argue that it is still possible to discover new plant uses in the Mediterranean and provide new insights in the process of diffusion, transmission and separation of ethnobotanical knowledge, without necessarily studying remote areas. The main objective of this study is to analyze, through quantitative indicators, the extent of the current knowledge on medicinal uses of plants in the Monti Sicani Regional Park. Moreover, this study is aimed at evaluating the features of uniqueness and commonality of this knowledge transmitted through generations by the descendants of the ―Sicani people‖ in comparison with other Italian and Mediterranean areas. 2. Materials and methods 2.1. Study area The investigated area is located in the district of the Sicani Mountains (central-western part of Sicily). It covers a surface of about 2300 Km2, (about 37.40-37.87 latitude; 13.18-13.63 longitude) and includes 32 municipalities (Fig. 1). This area has been historically inhabited by the "Sicani people", who are probably among the first inhabitants of Sicily, around 2200 BC (Rizzuti, 2009). With the arrival of Greek and Phoenician colonizers, the Sicani people were relegated in mountainous areas, which today are called ―Monti Sicani." Later on, during the Carthaginian colonization (V century BC) the Sicani people were partially subdued and in 241 BC were adjoined to the Roman Empire. The presence of this ancient population is still vivid with several archeological remains, especially in the localities of Prizzi, Lercara Friddi, Castronovo di Sicilia and Sant'Angelo Muxaro (where it is located the ancient residence of the Sicano king, Kokalos). The altitudinal range of the study area spans from 300 to 1613 m a.s.l. and the climate is typically Mediterranean. According to Rivas-Martinez (Rivas Martinez and Loidi Arregui, 1999; Rivas Martinez et al., 2002) the area belongs to the meso-Mediterranean thermotype. The mean annual rainfall is 640 mm (AA.VV., 2000); while the rainy days are mainly limited to the AutumnWinter period, while rain showers are rare over the summer. Snowfalls are infrequent and occur only at altitudes above 1000 m a.s.l. The soil associations are referred to Typic Xerorthents, Lithic Xerorthents, Typic and/or Vertic Xerochrepts in the part of territory in the hilly areas and to Typic 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 and/or Vertic Xerofluents, Typic Chromoxererts and/or Typic pelloxererts in valleys and lowland (Fierotti, 1997). The biodiversity (plant species and communities) of the Monti Sicani Regional Park is considerably high. A total of 850 vascular plants grow in the park and among these 68 (9.5%) are endemic. The forest areas cover a high surface and are mainly characterized by evergreen and deciduous oaks Quercus ilex L., Q. suber L., Q. gussonei (Borzì) Brullo and, Q. pubescens Willd. s.l.. Nevertheless, other tree species enrich the woodland diversity (e.g., Castanea sativa Miller, Acer campestre L., A. pseudoplatanus L., Fraxinus ornus L., F. angustifolia Vahl, Ulmus minor Mill., Ilex aquifolium L.). Forested areas are intermixed with traditional olive and fruit tree orchards and agricultural fields, where local farmers grow cereals, fodder, and vegetables. In the area, pastoral activities are also common, as well as a local craftsmanship based on traditional techniques passed down from generation to generation by the so-called ―old-masters‖. 2.2. Field interviews The current extent of the ethnobotanical knowledge in the Monti Sicani Regional Park was assessed through interviews with elderly people who have spent their lives in the study area and practiced traditional farming (agriculture and livestock breeding). Interviews were carried out between 2009 and 2010 in all the 32 municipalities (Fig. 1). In the protocol of study, it was determined a minimum sample of 10 respondents for each municipality, who, with an age above 60 years. This age requirement was decided in order to gain information over a long time span. In each municipality we sought for potential informants in gathering venues of elderly people and we solicited other information about other potential informants through a snowball sampling (Bernard, 1988). Interviews followed a semi-structured format (Bernard, 1988) without time limit. Interviews were generally individual, rarely in group discussions. The study was carried out following the ISE code of Ethics (ISE 2006), informants were made aware of the scope of the study and Prior Informed Consent (Rosenthal, 2006) was requested verbally. The language used during the interviews was Italian, and in some cases, the Sicilian dialect. Informants were stimulated to talk freely about their ethnobotanical knowledge, and were asked to mention all the medicinal plants known or used (with a special focus on herbaceous plants and shrubs), asking them the following questions: a) Which plant do you know, use or have used for medicinal purposes? b) How do you use these plants (e.g., plant part, preparation, mode of administration)? c) Where do you gather these plants? d) What is, in your opinion, the efficacy of these remedies (or plants)? Data on plant uses were reported in a pre-organized form. In this form we listed all the plants with medicinal properties mentioned by the informant, the vernacular name, the plant parts, the gathering period and sites, the frequency of use, the attributed medicinal properties and efficacy of preparations, and the methods of preparation. Information included also the date and the town where the interview was conducted, the name, age, gender, and level of education for each informant. Interviews began in private houses, cafeterias, clubs and continued in the surrounding fields and other places used for gathering medicinal plants. Informants were asked to indicate the used plants, which were then collected and coded. Plants were identified using the Italian Flora (Pignatti, 1982). Plant nomenclature was updated using online databases (e.g., TROPICOS, The Plant List). Samples were made into herbarium specimens and deposited at the Herbarium of the Research Consortium Corissia belonging to the ―Assessorato delle Risorse Agricole e Forestali‖ of the Sicilian Region (www.corissia.it). 2.3. Data analysis Data collected were digitalized and organized in a simple spreadsheet database. Data (plants and uses) were compared with other uses reported in ethnopharmacological literature (studies in other 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Italian regions and some Mediterranean countries), in order to highlight commonalities and differences. The collected ethnobotanical information was analyzed in order to highlight the number of most cited species and medicinal uses, the most commonly used parts of the plants (leaves, stems, etc.) and the most common preparation methods. The species were grouped into n categories of illnesses defined according information given by the informants. In this way, we reported the information received by the informants exactly as it was given to us, without contamination or manipulation of the data. We then applied the following ethnobotanical quantitative indices: (1) Cultural Importance Index (CI) (Pardo de Santayana et al., 2007) – it quantifies the most cited, currently used, species by informants. The index is calculated as follow: ∑ = UR/N, where UR (Use Report) is the use recorded for each species and N is the total number of informants. This index estimates the cultural significance of each species, or rather verifies, in quantitative terms, to what extent each species is present in the popular culture and in the memory of the inhabitants involved in the survey. (2) Ethnobotanicity Index (EI) (Portères, 1970) – with reference to medicinal species – it determines the ratio between the number of used medicinal species and the total flora of the study area, expressed as a percentage. This index is used to verify the proportion of species considered useful in folk medicine by the Sicani people in their surroundings and provides an idea of the importance of medicinal species in a given area. (3) Index of Ethnobotanical Diversity (H) (Begossi, 1996) – determined using the ShannonWiener index and the formula H = - ∑ (pi ln pi), where ‗pi‘ is the ratio between the number of citations per species and the total number of citations. This index is used to estimate the level of diversity of the different species in the investigated plant community, taking into consideration the relative abundance of citations of the species. According to Begossi (1996), a high number of citations indicates a low diversity level or greater dominance in the use of the same species. (4-5) Ethnobotanical Richness (R) and evenness index (E) (Begossi, 1996): the ethnobotanical richness is the number of useful medicinal species and the evenness index is calculated using the formula: E = H/Hmax, where Hmax = ln R. The evenness index is between 0 and 1, where 0 means complete heterogeneity and 1 complete homogeneity in the uses of the plants. (6) Informant Consensus Factor (ICF) (Trotter and Logan, 1986) - was determined using the following formula ICF = Nur – Nt/Nur – 1, where Nur refers to the total number of use reports for each illness category and Nt indicates the number of species used in that category. This index is used to test the homogeneity of knowledge shared by the informants. A high value in this index (near to 1) indicates that there exist well-defined selection criteria for the species regarding a specific illness category on behalf of the informants and/or that they are in agreement in using that species for a specific use, whilst a low index (near to 0) indicates the choice of the species is random and that there is no consensus amongst the informants on the medicinal use of the species. 3. Results and discussion 3.1. Demographic characteristics of respondents The demographic data of the informants are reported in Table 1. The age of respondents varies from 60 to 90, with an average age of 72.2 years. The highest number of cited plants has been obtained by people aged between 71 and 80 years while less information has obtained by the other younger or older informants. In the first case, it could be due to an advanced and progressive detachment from the values of ―rural culture‖ and ―rural development‖. In the second case, we 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 argue, according to our observations in the field, that the little information obtained could probably be justified by a certain reluctance and/or objective difficulties in participating to interviews. In twenty-nine of the thirty-two municipalities, we have been able to survey only male informants. The prevalence of men in the sample of respondents was mainly due to gender issues of being in a conversation with a male stranger (the interviewer). Since it has been observed in the Mediterranean areas, but also in other geographical regions, that the women are generally the most knowledgeable informants as regards medicinal plants (Hardy, 2000), we acknowledge the fact that this could have partially affected our results. The 80% of respondents are farmers, or shepherds, still active or retired, the 20% were masons, laborers and housewives. The majority of respondents have not completed secondary school. 3.2. General data on medicinal plants A total of 108 wild plants are reported as being used for medicinal and veterinary purposes (Table 2). The medicinal plants belong to 43 families. In table 2, for each species we provide the scientific name, the use, vernacular name (in Sicilian dialect), the ethno-pharmacological information as provided by informants, the method of preparation, the therapeutic uses, the number of citations for each use, the current use of the species and the level of perceived usefulness. Table 2 also shows the similarities in the use of medicinal species among the investigated area and those reported in studies in other Italian regions and Mediterranean countries. The most represented families are Asteraceae (20 species), Lamiaceae (11 species), Apiaceae (6 species) and Asparagaceae (5 species). The high proportion of medicinal species in the Asteraceae and the Lamiaceae families has already been reported in other ethnobotanical studies in the Mediterranean area (e.g., Merzouki et al., 2000; Benitez et al., 2010; Cakilcioglu and Turkoglu, 2010). This is probably due to several phytochemical (and derived cultural) factors (e.g., bitter taste considered healthy due to lactones in several Asteraceae species, smell and aromatic compounds in the Lamiaceae species, Guarrera and Savo, 2013). In most cases the recorded species have different vernacular (dialect) names in the 32 investigated municipalities. Conversely, different species of Malvaceae and especially Lamiaceae, have been indicated, by many people, with the same dialect name. In total, 194 different vernacular names were used by the respondents to indicate the 108 recorded species. The fact that vernacular or common names are rarely reported, and the fact that not all the species are also used in other Sicilian areas, did not allow us to assess the uniqueness of the folk nomenclature in the Monti Sicani Regional Park. The comparison with vernacular names reported for other Italian regions is not feasible because of the singularity and uniqueness of the Sicilian dialect (Lo Piparo, 1990). In the census were also included some species considered toxic (6 records). This is not uncommon, since all medicinal plants contain active principles that could have toxic effects, at higher dosage (Blackwell, 1990). Generally, the species that are considered more toxic by the people living in the Sicani area are used externally, as it is common in other Italian or Mediterranean areas (e.g., Guarrera, 2006; Tetik et al., 2013). The therapeutic use of toxic species is often reported in the ethno-pharmacological literature (e.g., Leporatti and Ivancheva, 2003; Leporatti and Imperi, 2007; Aleo et al., 2011). A particular use of a toxic species, which is not strictly medicinal, is that of Euphorbia rigida M. Bieb. as ichtyotoxic. Many Mediterranean Euphorbiaceae species are rich in irritant sap, which, is used especially in fresh water courses, to stun fish (Savo et al., 2013). According to the interviews it seems, however, that this illegal fishing practice is no longer in use. The majority of species are collected in the wild, or more rarely, gathered in the wild and then planted in kitchen gardens. Natural habitats such as fallow fields, pastures, hedges and woods resulted as the favorite habitats for gathering medicinal species. Although cultivating the plants in kitchen would ensure their availability potentially throughout the year, informants still prefer to gather the plants in the wild. Among aromatic herbs some, such as mints, are collected from natural 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 habitats (e.g., humid areas and untilled soils), while others, such as rosemary and sage, are often cultivated on balconies for medicinal but also food and ornamental purposes. 3.3. The most frequently cited species The list of the most frequently cited (and still used) species by the informants is reported in Table 3. The most frequently cited species are also those that are more commonly used by people in the area for therapeutic uses. Several of these species are also among the most cited species for the Sicilian region (Leonti et al., 2008). It is important to emphasize that some species are also used as food and as aromatic. According to the informants, the dishes prepared and aromatized with these plants have additional healthy properties other than nutritional qualities. This is not new in Sicilian folk tradition as highlighted by Lentini and Venza (2007) in a multi-year study in different Sicilian areas. Several food plants are often consumed for their healthy or medicinal properties in Sicily but also in other Italian areas (Guarrera and Savo, 2013). Most of the plants that are highly cited are also highly appreciated by the informants. Among the species that are still practiced by the people living in the Sicani area, the 61.22% of the therapeutic uses considered rather effective. Some of the most cited species are discussed below, including information on their phytochemical profile and pharmacological activities. Cichorium intybus (62 informants mentioned the plant for medicinal purposes, 54 citations of uses, 1 plant-use) is the most cited species by the inhabitants of the Monti Sicani Regional Park. The aerial parts of this plant species are commonly eaten boiled for their taste but also for their bland diuretic properties which are particularly appreciated by local people. The plant contains several active principles [e.g., lactucin, lactucopicrin, lactucin like guaianolides, phenols, flavonoids, stigmasterol, g-sitosterol (Guarrera and Savo, 2013 and references therein) and is generally retained depurative and healthy as many other plants with a bitter taste. Cichorium intybus is well known in the Italian ethnobotanical folklore (Lentini, 2000; Guarrera, 2006; Guarrera and Savo, 2013), but also in the Mediterranean [e.g., in Morocco (Joaud et al., 2001), in Tunisia (Leporatti and Ghedira, 2009), in Spain (Benìtez et al., 2010)]. Athamanta sicula, locally known as "spaccapetri" and "spezzalipetri" (―stone-breaker‖), is used as diuretic and to facilitate the elimination of kidney stones (57 informants, 57 use-citations, 1 plant-use). The genus Athamanta is restricted to Southern Europe and consists of nine species, many of which have an ethnobotanical use (Tomic et al., 2009). This plant contains several active principles (e.g., myristicin, apiol) which however, seems to vary according to the plant part analyzed and location of collection (Camarda and Di Stefano, 2003; Camarda et al., 2008). The roots, which are used by our informants, have not been biochemically characterized yet. The decoction and infusion of the leaves and aerial parts of Malva trimestris (57 informants, 65 use-citations, 3 plant-uses) are used against inflammation of the oral cavity (21 use-citations) and disorders of the digestive system (41 use citations). Interesting (3 use-citations), although very rare, is the use of such preparations to promote the maturation and healing of fistulas; this particular use of Malva trimestris seems to be new for Italy. Malva trimestris contains as other Malva species, protective mucilage which have emollient activity on the digestive system, also phenolic compounds and flavonoids [e.g., p-coumaric, ferulic, caffeic acids and kaempferol (Głowniak et al., 2005)] with antioxidant and antimicrobial activities (Skalicka-Wozniak et al., 2007). Opuntia ficus-indica (48 informants, 48 use-citations, 2 plant-uses) is used as anti-inflammatory (32 use-citations) and digestive (16 use-citations) having beneficial properties for the urinary and gastrointestinal tracts. Similar data are reported for several regions in Southern Italy (the plant is a thermophilous species) but also in other Mediterranean countries (Table 2). This plant, which has spread in semi-arid areas of the Mediterranean after its introduction from Americas, has been widely introduced in local folk pharmacopeias. Opuntia ficus-indica contains several active molecules [e.g., vitamins, betalains, flavonols (Butera et al., 2002, Galati et al., 2003)] and several tested pharmacological activities [e.g., antiulcer, antioxidant (Galati et al., 2001; Galati et al., 2003; 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Tesoriere et al., 2004)]. These properties could explain the high appreciation for this species and the different health problems for which it is used. Among the species for veterinary use the best known and widely used is Helminthotheca echioides for its efficacy in the care of wounds in the form of juice or poultice. Equally sought in veterinary folk medicine is Ruta chalepensis, whose decoction of leaves and branches is used to facilitate the expulsion of the placenta to sheep or cows after labor. Extremely rare in the Monte Sicani territory is the veterinary use of Helleborus bocconei subsp. siculus (1 informant, 1 usecitation, 1 plant-use), locally known as "raricchiu." The roots of this species were once used to treat pneumonia in horses and cattle. 3.4. Medicinal uses The species listed in this paper have been grouped into 8 categories of therapeutic use (as reported by informants) (Table 4). The majority of the plant species are used to treat a single disease: the 74.54% of the species has a single therapeutic indication, the 18.18% two, and the 7.27% three indications. A high number of species is used for the treatment of articular problems (23.81%) or skin affections (13.49%) such as bleeding, skin diseases, inflammation of the skin, scars and skin burns, bruises, rheumatism, etc. This predominance can be explained by the kind of occupations of the informants (mainly agro-pastoralists). Wounds, blisters, sores are indeed common problems while working outdoor and generally require immediate medication. Bonet et al. (1999) emphasize the effort of people, in different areas, in searching for natural and effective remedies against skin and traumatic problems while in the field (where appropriate hygienic conditions were lacking as well as drugs for simple application). Still in the Iberian region, for example, where rural traditions and activities are still alive, especially in the inland areas, several authors have emphasized the use of plants in the treatment of skin diseases and joint system problems (Akerreta et al., 2007; Neves et al., 2009). Many plant species (20.63%) are used for the treatment of gastrointestinal problems and specifically for treating digestive and gastrointestinal disorders. This same pattern has been highlighted for the whole Sicilian region (Leonti et al., 2008). The use of plants as digestive is rather widespread in the folk medicine of the Sicani area; many of these species contain bitter substances (e.g., many Asteraceae species) and have eupeptic properties (e.g., Pieroni and Heinrich, 2002; Guarrera and Savo, 2013). The 11.90% of the species are used for the treatment of physical and metabolic disorders. This is probably explained by the fact that a wide array of pathologies can be grouped included in this category (Neves et al., 2009). Few species are used for the treatment of diseases of the urinary system; this is probably due to the unbalanced gender ratio, since these problems are generally more common among women. Few species are also cited for the treatment of problems to the respiratory system (6.35%) and this could be also due to gender issues, since syrups for cough often contain more species and their preparations is generally gendered. No species was cited by respondents as having therapeutic properties stimulating the activity of the nervous system. A total of 144 medicinal uses (including veterinary uses) are reported for the Sicani area. Among these, 135 are common and/or similar to those reported in other Italian regions or Mediterranean countries. Differences and commonalities can be attributed to different phytogeographic features, but also local plant biodiversity, methods and aims of the studies and cultural differences. Interestingly, the use of many species is spread, but limited to the Sicilian region (e.g., Rhus coriaria, Athamanta sicula, Senecio delphinifolius, Mandragora autumnalis). Even though several commonalities and similarities of medicinal uses among other areas do exist, we have also been able to highlight some specific and unique features of the area. According to our bibliographic comparisons, at the best of our knowledge, 9 plant uses have not been mentioned before and seems to be characteristic of the ethnopharmacological knowledge of the Monte Sicani Park area (see section 3.7). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 While the area seems to have a distinctive ethnobotanical profile, it is also true that the pace of cultural erosion is alarming. In our investigation we noted that the usage of the 33.79% of species are still practiced while the remaining majority of plant uses are obsolete. Moreover, even the uses that are still actual are practiced with a low (once a month) or very low (once a year) frequency by the local people. Only few species, among the most cited (e.g., laurel, chicory and mauve) are used more frequently (once a week). 3.5. Parts used and method of preparation The preferred plant parts used in the Sicani area are reported in Fig. 2. The predominant use of the leaves in the investigated area is in agreement with data reported in literature. According to several authors, the ease of collection in nature and the abundance of leaves compared to the other organs of the plant, can be two reasons that explain the higher frequency of their use in folk medicine. This could also be related to the fact that many plants are used as vulnerary and leaves could easily being used as extemporaneous bandage. Little less used are flowers and hypogeous organs. Interestingly, several informants reported that fruits generally contain more poisonous substances. This is probably related to the high presence of more or less toxic plants in the medicinal flora of the Sicani Regional Park (see also Aleo et al., 2011). In most cases, the different parts of the plant are used for a single use. However, according to the information recorded in the interviews, more than one single part of the same plant can be used in combination or, in some cases, more parts of the plant can be used interchangeably for the same preparation. For example, both leaves and flowers of Sambucus nigra are used for the treatment of wounds and bruises, the roots and leaves of Rubus ulmifolius are both retained effective for healing hemorrhoids. Plants are used both internally (decoction and infusion) and externally (direct application, poultice and ointment). The decoction (76 records) represents the most frequent method of preparation, followed by poultice (29), direct application of the plant (27), infusion (16), and ointment (3). However, it has not always been possible, during the interviews, to obtain a clear distinction between poultice and crushed plant plaster or ointment. Some plants are either consumed or used in some sort of preparation for the same therapeutic purpose. For example, Cynara cardunculus is eaten for its healthy effects on the liver while the broth produced in the cooking process is consumed for the same reason; the leaves of Nasturtium officinale, are consumed in salads for their attributed diuretic properties. Dosage and frequency of application are not provided in this paper. We preferred to omit this information since informants (predominantly men), were often vague or inaccurate about posology. A further investigation in the area, with a more balanced gender ratio, or even more focused on female informants, would be necessary to better disentangle the ethnomedicinal knowledge of the Sicani descendants. 3.6. Quantitative analysis According to the calculations of the Cultural Importance Index (CI) (Table 3) Malva trimestris, Athamanta sicula, Cichorium intybus and Cynodon dactylon are the most important species from a cultural point of view in the Sicani area. Among these species, Cichorium intybus is a food medicine while the others are strictly medicinal. The values of CI are not high and, if compared with those reported in other studies, can be considered quite low. This can be explained by the fact that our sample of respondents is rather high in comparison with other case studies. Among the most cited species in the survey, the lowest value of CI was found for Laurus nobilis, Mentha pulegium and, Rubus ulmifolius (0.09), more generally known by the people of the Sicani area for their aromatic properties or food uses. Although Laurus nobilis is highly reported in other studies conducted in Sicily, in the Sicani area it has been cited rather rarely (21 citations). During the interviews this plant was preferentially mentioned for its use in the preparation of cured meat or as aromatizer. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 As regards the Ethnobotanicity Index (EI), the 12.70% of the total plant species listed in the flora of the Monti Sicani Regional Park are known to be useful in folk medicine. The value of this index, in comparison to values reported in other Italian studies, is rather high considering the low percentage of female informants and the fact that the interviewer solicited information especially focusing on herbaceous species and shrubs. The value, however, is lower and in general far from the average of the values of EI calculated in some Iberian areas (Table 5). This could be explained by the more enlarged concept of medicinal species than has been applied in the calculation of the index in those areas. The Shannon-Wiener index is equal to 4.17, the species richness of the study area is equal to 108, and the equity index is 0.88. The comparison with Begossi (1996) showed a lower ethnobotanical diversity in the Monti Sicani Park, justified by different citation numbers but especially by the differences in species richness and climate features between the study areas. Comparing the values of H (Index of Ethnobotanical Diversity) and E (Evenness index) with those reported in some studies in Mediterranean areas whit similar floral richness and latitude, as some areas of Spain (Bonet et al., 1992; Akerreta et al., 2007) differences are still present but lower. The factor of consensus (ICF) of the respondents has been calculated for each category of medicinal uses, and it is reported in Table 4. ICF values close to 1 were found for several categories with an average value of ICF, for all categories, of 0.87, which shows a very high level of consensus; this value is also comparable to those reported in other studies carried out in Sicily (Leto et al., 2013) and the Mediterranean (e.g., Agelet and Vallès, 2001; Camejo-Rodrigues et al., 2003). The high values of ICF found in most of the categories of medicinal uses can be explained by the fact that there is a high homogeneity of consensus among informants about the therapeutic use of a set of species and their about their efficacy. For example, the category "diseases of the urinary system" includes 11 species, and has a value of ICF equal to 0.96 which indicates the existence of a great homogeneity in the consensus among respondents for the medicinal use of those species. Considering also the level of appreciation for many species belonging to different categories it was found a strong correlation between the value of ICF and the degree of appreciation, although this is highly subjective. The lowest value of ICF (0.76), found in the category "diseases of the skin", indicates that the 17 species belonging to this category are not retained very effective by the informants. 3.7. Unreported medicinal uses Among the uses cited by our informants, some seems to be new (or at least not previously reported). Vicia hirsuta and Kickxia elatine are used for the treatment of hyperhidrosis of the feet; this specific kind of use may be related to the long hours spent working in the fields by farmers (Grillo, 2010). The uses of Mentha pulegium for liver disorders, of Malva trimestris for fistulas and of Lavatera agrigentina Tineo for cough and bronchitis seem also to be new. Lavatera agrigentina, commonly called ―marva di luppina‖, is a Sicilian endemic species growing on clay substrates. This plant shares similar properties to those typically attributed to many Malvaceae species, such as emollient qualities and, depending on doses, as laxative properties (Guarrera, 2006). Among these species only Kickxia elatine is still used as medicinal by the local people of the Sicani area and also presents a high degree of appreciation. This species is used as wound healing agent in Asia and contains several flavonoids (Yuldashev et al., 1996). Biochemical and pharmacological studies on this plant, however, are very few. As it is possible to see in Table 2, all other species have a low number of quotes by the informants. This observation could be interpreted as reduction of the ethnobotanical knowledge still possessed by local people. The results of the interviews and the quantitative analysis pointed out, indeed, a fast process of cultural erosion and are indicative of an early disappearance of these species from the medicinal folklore of the Sicani Regional Park. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 4. Conclusions The ethnobotanical survey showed that the majority of the therapeutic uses of wild plants are no longer practiced nowadays in the Sicani area. Only a few remain in the memory of the elderly, having the modern medicine gradually replaced the folk medicine, probably for the ease in the supply of synthetic drugs and their fast efficacy. Moreover, the under-representation of women in the sample of informants probably contributed to lower the amount of useful and detailed information, in particular, methods of preparation and administration of therapeutic preparations. In the various municipalities of the Sicani Park there were no substantial differences regarding the phytoterapeutic use of the same plant species (along with plant parts and preparations). The high internal consensus is however juxtaposed to a strong cultural specificity. The quantitative analysis carried out showed that the percentage of species recognized useful for their medicinal properties is relatively low compared to the overall floristic richness of the study area. This could be seen as an evidence of the ongoing process of cultural erosion, considering also the frequency of use and the degree of appreciation of the species. The index of cultural significance has shown, in particular, that few species would fit in the category food medicine, while in Sicily the number of these species is rather high (Lentini and Venza 2007). For most of the categories of therapeutic use, the consensus among the respondents was very high compared to other studies, emphasizing a high uniformity in the use of specific species for certain diseases. The comparison with other pharmacological and ethnobotanical studies carried out in other Italian regions and abroad has shown that the majority of the medicinal uses are common or similar to those reported in bibliography. Some therapeutic uses, however, seem to be "new" in literature. Although some therapeutic uses seem to be "new" in literature, the highlighted cultural erosion could have already eliminated important pieces of the ethnobotanical knowledge of the Sicani area. The investigation carried out in the Monti Sicani Regional Park represents a first quantitative and detailed contribution to the ethnobotanical exploration of the area. The investigation should not, however, be considered exhaustive. In the future it would be necessary to extend the research to the younger generations and including more women in order to better understand the complex processes of transmission of knowledge across generations and between genders. We hope that this study will stimulate other researchers in exploring other areas in Sicily for discovering its rich and variegate intangible cultural heritage related to plant uses. Acknowledgements We are grateful to all the informants who participated in this study and shared their knowledge with us, without them this research would have been impossible. 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Captions of figures and tables 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Fig. 1. Geographic position of the study area, with details of the municipalities within the Monti Sicani Regional Park. Fig. 2. Frequency of plant parts used for medicinal preparations. Absolute values are reported at the end of the bars. Table 1. Demographic features of the informants and number of cited plants by age group. Table 2. Ethnobotanical uses of plants in the Monti Sicani Regional Park. Table 3. List of wild medicinal plants most frequently cited and currently used by informants along with the Cultural Importance Index. Table 4. Illness categories of wild medicinal plants in the Monti Sicani Regional Park with the associated Informant Consensus Factor. Table 5. Comparison of the ethnobotanicity index (EI) of the study area with those of other localities in Central-Southern Italy and the Iberian Peninsula. Table 1 Table 1 Demographic features of the informants and number of cited plants by age group. Total Number of informants Number of cited plants 230 108 102 92 36 72 91 67 Age group 60-70 years old 71-80 years old 81-90 years old Table 2a Ethnobotanical uses of plants in the Monti Sicani Regional Park. Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Acanthaceae Acanthus mollis L. (CORISSIA - S/0040) biancarussina Root Pimples, warts Finely chopped root 4 C L ALG (1) Leaf To increase milk secretion in Fodder the cattles Haemostatic, wounds Cataplasm 8 C H 2 LAT (1); SIC (1) CAM (2); SIC (4) Common SPA (1) ABR (3); APU (1); CAL (1); CAM (3); LAT (4); MAR (1); SAR (4); SIC (2); TUS (2) Common GRE (1); SPA (3) Aerial part, leaf Adiantaceae Adiantum capillus-veneris L. (CORISSIA - S/0183) Adoxaceae Sambucus nigra L. (CORISSIA - S/0330) Sambucus nigra L. (CORISSIA - S/0330) Amaranthaceae Beta vulgaris L. (CORISSIA - S/0251) Anacardiaceae Rhus coriaria L. (CORISSIA - S/0306) SIC (3); TUS (1) capiddu santuveniri, capelvenere Frond Abortive Decoction 2 savucu Flower, leaf Haematomas, sprains, wounds, swelling Cataplasm, decoction 18 zarchideddi di giri Leaf Abscesses, pimples Cataplasm 1 LAT (1); LIG (1); PIE (3); SIC (2) Common summaccu Leaf Hyperhidrosis of the feet Direct application 7 SIC (7) Leaf Anti-inflammatory gastrointestinal system Decoction, fresh or cooked leaf 16 LIG (1); TUS (2); SAR (1) Apiaceae Apium nodiflorum (L.) Lag. scavuna, accina (CORISSIA - S/0090) servaggia C C H Athamanta sicula L. (CORISSIA - S/0221) spaccapetri, spezzalipetri Root Kidney stones Decoction 64 H SIC (2) Conium maculatum L. (CORISSIA - S/0009) cicuta, cicutedda Aerial part Haemorrhoids Cataplasm 3 SAR (1); SIC (1) Eryngium campestre L. (CORISSIA - S/0143) panicavuru Root Diuretic Decoction 4 APU (1); CAM (2); SIC (4) Table 2b Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries C H APU (1); ABR (2); BAS (2); CAL (1); CAM (4); LAT (2); LIG (2); MAR (1); MOL (1); SAR (2); SIC (9); TUS (4) Common ALG (1); CYP (2); EGY (1); GRE (1); MOR (2); POR (2); SPA (3); TUN (1) SIC (1) SPA (2) CAM (1); SAR (1) LEB (1); MOR (1); TUR (1) Foeniculum vulgare Miller finuacchi (CORISSIA - S/0038) sarbaggiu, finuacchi i muntagna, finocchi Aerial part, fruit, root Digestive Decoction, infusion 35 Ridolfia segetum Moris (CORISSA - S/0217) finuocchiu anitu Root, stem Stomach acidity Root or stem eaten 2 lannaru Sap Warts, pimples Direct application 2 anzaru Leaf, rhizome Wounds Cataplasm 2 BAS (3); CAM (1); SAR (2); SIC (1); TUS (2) edira, edera servaggia Leaf Burns, contusions Direct application 1 Leaf Airways inflammation, bronchitis, cough Decoction 2 ABR (2); CAL (1); CAM POR (1); SPA (1); TUR (1); LIG (1); SAR (3); SIC (1) (1) Common CAL (1); CAM (1); SIC GRE (1); TUR (1) (2) zabbara, zabbaruni Leaf Haematomas, pimples, swelling, wounds Cataplasm 2 sparaciu nivuru, sparaci nivuri, asparaciu, sparacogna Turion Diuretic Decoction 17 C Turion Turion Turion Digestive, refreshing Hypertension Diuretic Decoction Decoction Decoction 9 1 2 C Bulb Contusions, haematomas, wounds Cataplasm 7 Apocynaceae Nerium oleander L. (CORISSIA - S/0105) C H Araceae Arum italicum Mill. (CORISSIA - S/0196) Araliaceae Hedera helix L. (CORISSIA - S/0323) Asparagaceae Agave americana L. (CORISSIA - S/0119) Asparagus acutifolius L. (CORISSIA - S/0202) Asparagus albus L. (CORISSIA - S/0228) sparaciu biancu, sparaci bianchi Drminia maritima (L.) Steam (CORISSIA S/0008) cipuddazzu C L APU (1); CAM (1); LIG (1); SAR (1); SIC (3) ALG (1); SPA (1) H ABR (2); BAS (3); CAM (1); LAT (1); MAR (1); MOL (1); SAR (2); SIC (2); TUS (1) Common CYP (2); POR (2); SPA (2); TUR (2) H SIC (1) SAR (1); SIC (1) ABR (2); BAS (1); LAT (1); MOL (1); SAR (1); SIC (1) APU (1); BAS (1); CAL (1); SAR (1); SIC (3) ALG (1) LEB (1); SPA (1) ALG (1); CYP (1); MOR (1); SPA (1); TUR (2) Table 2c Table 2 (continued) Common/similar use in other Mediterranean countries Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Ruscus aculeatus L. (CORISSIA - S/0363) sparaci di trona, sparaci di tronu Aerial part Diuretic Decoction 3 C H Aspleniaceae Ceterach officinarum DC. (CORISSIA - S/0104) spaccapetri Whole plant Renal colics and kidney stones Decoction 5 APU (2); BAS (3); CAM (2); SIC (6) Common Asteraceae Achillea ligustica All. (CORISSIA - S/0075) millefogliu Aerial part Intestinal worms, stomach pain Juice added to sugar 2 CAM (1); MAR (1); SAR (2); SIC (3); TUS (2) Anacyclus tomentosus (Desf.) Pers. (CORISSIA S/0199) Anthemis arvensis L. (CORISSIA - S/0086) camumidda, Flower aumidda, camumilla aumidda, umidda Aerial part, flower Sedative Infusion 7 SIC (2) Sedative Decoction 2 TUS (2) Aerial part, flower Digestive, refreshing Decoction 2 BAS (1); TUS (1) MOR (1); SPA (2); TUR (1) Decoction 14 CAM (1); LIG (1); SAR (2); SIC (7) EGY (1); SPA (1) ABR (1); APU (1); BAS LEB (1); TUR (1) (3); CAM (1); LAT (1); SAR (1); SIC (1); TUS (1) Common TUR (6) CYP (1) Artemisia arborescens (Vaill.) L. (CORISSIA S/0262) Asteriscus spinosus (L.) Sch. Bip. (CORISSIA S/0326) erva bianca Aerial part, leaf Intestinal worms, stomach pain erva stidda Leaf Haemostatic, sprains, wounds Cataplasm 1 SIC (3) SPA (1) Renal colics, kidney stones Decoction 4 SIC (1) CYP (1) Centaurea calcitrapa L. (CORISSIA - S/0329) apuarchiu, aporchiu, approcchiu cicoria, cicuaria Aerial part, leaf Aerial part Haematomas, sprains, wounds, swelling Cataplasm 3 SAR (1); SIC (2) Aerial part Diuretic Decoction, broth 54 C H BAS (2); CAL (1); CAM MOR (1); SPA (1); TUN (1); LAT (1); LIG (1); SIC (1); TUR (1) (6) Common Constipation, gastritis Decoction 4 C H ABR (1); MAR (1); SAR (2); SIC (2) Liver disorders Boiled vegetables, broth 3 C H ABR (1); BAS (2); CAL MOR (1); SPA (2) (1); CAM (5); FRI (1); LAT (2); MAR (2); MOL (1); SAR (3); SIC (1); TUS (1) Common Cichorium intybus L. (CORISSIA - S/0026) Cynara cardunculus L. (CORISSIA - S/0154) carduna, carduna Leaf, root sarvaggi, carduna spinusu Leaf MOR (1) Table 2d Table 2 (continued) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Crepis vesicaria L. (CORISSIA - S/0036) cicuriuni Aerial part Digestive, refreshing Broth 3 Dittrichia viscosa (L.) Greuter (CORISSIA S/0280) Helminthotheca echioides (L.) Holub (CORISSIA S/0176) Hyoseris radiata L. (CORISSIA - S/0070) brucara, purcara, vrucara Leaf Haematomas, wounds, swelling Cataplasm, direct application 46 C L CAL (1); LIG (1); SAR (1); SIC (7) Common aspredda, spredda, Leaf spiredda Haemostatic, wounds (veterinary use) Cataplasm, juice 7 C L SIC (1) cicuriuni, cicoria sarvaggia, pidicudda Aerial part Diuretic Decoction 6 SIC (2) Matricaria chamomilla L. (CORISSIA - S/0380) camumidda Flower Sedative, digestive Infusion 2 ABR (1); BAS (2), CAL CYP (2); GRE (1); MOR (3); CAM (4); LAT (1); (1); POR (2); SPA (3); LIG (2); LOM (2); MAR TUR (4) (1); MOL (3); SAR (5); SIC (2); TUS (2) Common Pulicaria odora L. Rchb. (CORISSIA - S/0379) soppiu Whole plant Haemostatic, sprains, swelling, Decoction wounds 7 SIC (1) Senecio delphinifolius Vahl. aumidda, Aerial part, (CORISSIA - S/0081) camumidda, flower umidda Sonchus asper (L.) Hill cardedda Aerial part (CORISSIA - S/0077) maschili, cardedda sarvaggia, cardedda spinusa Sedative Decoction, infusion 25 C H SIC (2) Digestive Decoction 13 C H ABR (1); APU (1); BAS (2); CAL (1); CAM (1); SAR (1); SIC (1) SPA (1); TUR (1) Sonchus oleraceus (L.) L. (CORISSIA - S/0364) cardedda fimminina , cardedda manza Aerial part Digestive, refreshing Broth 40 C H ABR (1); BAS (1); LIG (1); SAR (1); SIC (2); TUS (1) ALG (1); SPA (1) Sonchus tenerrimus L. (CORISSIA - S/0364) cardedda, grespino sfrangiato Aerial part Digestive, refreshing Decoction 11 BAS (1); CAL (1); CAM (1); SIC (1) Tussilago farfara L. (CORISSIA - S/0182) ugna cavaddrina Leaf Skin disinfectant Cataplasm 3 ABR (1); BAS (1); CAL ALB (2); GRE (1); TUR (1); CAM (2); MAR (1); (2) LAT (2); SIC (3) Common SAR (1); SIC (1) CYP (1); POR (2) Table 2e Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Urospermum dalechampii caccialebbra, (L.) Scop. ex F.W. Schmidt coccia di lepre (CORISSIA - S/0001) Boraginaceae Borago officinalis L. (CORISSIA - S/0268) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Used plant part(s) Plant uses* Preparation methods Number of citations Aerial part Digestive disorders Broth 2 Laxative Cooked and used as condiment 18 C H APU (1); ABR (1); BAS GRE (1); MOR (2); POR (2); CAL (1); CAM (3); (2); SPA (1) FRI (1); LOM (1); SIC (4); TUS (3) Common Aerial part Duretic Decoction 20 C H MOR (1); POR (3); SPA (1); TUN (1) burrania, vurraini Aerial part SIC (1); TUS (1) EGY (1) Cerinthe major L. (CORISSIA - S/0314) sucameli Aerial part Haemorrhoids Decoction 1 ABR (1); CAM (3); SAR (1); SIC (8); TUS (1) Common SIC (1) Echium italicum L. (CORISSIA - S/0350) moccaru Whole plant Haematomas, wounds Direct application 1 SIC (2) ALG (1) Aerial part Wounds Cataplasm 2 CAM (1); SAR (1); SIC (2); TUS (1) Common ALG (1); CYP (1); GRE (1); POR (1); TUN (1) Nasturtium officinale R. Br. crisciuni, Aerial part (CORISSIA - S/0140) crisciuna, scavuni, pisciuna Diuretic Condiment 5 CAL (1); CAM (1); LAT (1); LIG (1); SIC (4) Common GRE (1); LEB (1); MOR (1); SPA (2) Digestive Decoction, infusion 16 C L APU (1); CAL (1); CAM (1); SAR (1); SIC (8); TUS (1) ALG (1); CYP (1); MOR (3) Flower Anti-inflammatory urinary system Decoction 32 C L CAL (1); SAR (1); SIC (8); TUS (1) Common (in Sicily and Sardinia) Leaf Pimples, burns, swelling, fistulas Cataplasm 2 ABR (1); CAM (2); SAR (1); SIC (4) Leaf Fistulas, haematomas, wounds Juice 4 BAS (1); SIC (3) Brassicaceae Capsella bursa pastoris L. cannistriddu, Medik. (CORISSIA vurzidda di S/0308) picuraru Cactaceae Opuntia ficus-indica (L.) Miller (CORISSIA S/0046) Crassulaceae Umbilicus horizontalis (Guss.) DC. (CORISSIA S/0097) ficudinia, sciura di Flower ficudinia, sciuri di ficudinia auricchi du parrinu, auricchi du re Cucurbitaceae Ecballium elaterium (L.) A. cucummariaddu Rich. (CORISSIA - S/0247) POR (1) Table 2f Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Dioscoreaceae Dioscorea communis L. Caddick & Wilkin (CORISSIA - S/0003) sparaci di succa, sparaci di serpa Leaf, stem Rheumatic pains Direct application 8 C H Leaf, stem Digestive Direct application 7 C L Aerial part Diuretic, prostate Decoction 13 C H Aerial part Kidney stones Decoction Aerial part Digestive mbriaculi Fruit camarruni, maccarruni camarruni Equisetaceae Equisetum arvense L. (CORISSIA - S/0349) Ericaceae Arbutus unedo L. (CORISSIA - S/0123) Euphorbiaceae Euphorbia characias L. (CORISSIA - S/0291) Euphorbia helioscopia L. (CORISSIA - S/0147) cuda di cavaddu, cuda cavallina Vicia hirsuta L. Gray (CORISSIA - S/0016) Hypericaceae LAT (2); SIC (1); UMB (1) Common ABR (1); APU (1); CAM (1); FRI (1); LIG (2); LOM (1); PIE (1); SAR (1); SIC (2); TUS (3) Common GRE (1); POR (1); SPA (1) 3 MOL (1); SIC (2) GRE (1); POR (1); TUR (1) Decoction 9 SIC (1) Digestive, refreshing Condiment 1 SAR (4); SIC (1); TUS (1) ALG (1) Sap Warts, pimples Direct application, toxic 3 ABR (1); APU (1); CAM (1); LAT (1); SAR (3); SIC (2); TUS (1) Sap Cist, tendonitis Direct application, toxic 2 ABR (1); BAS (1); CAM (2); LAT (1); MAR (1); SAR (2); SIC (1) Latex The poisonous sap is used to narcotize and then catch eels in river Toxic 4 SIC (3) liquirizia, niculizia Root Cold, cough Decoction 15 tupparola Hyperhidrosis of feet Direct application 1 Euphorbia rigida M. Bieb. rizzitiaddu (CORISSIA - S/0282) Fabaceae Glycirrhiza glabra L. (CORISSIA - S/0354) Common/similar use in other Mediterranean countries Leaf C L APU (1); ABR (1); BAS (2); CAL (1); SIC (3); TUS (1) Common SPA (2) CYP (2); EGY (1); GRE (1); MOR (1); SPA (1); TUN (1) Table 2g Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Hypericum perfoliatum L. (CORISSIA - S/0125) uagliu di pricò, pericò, piricò, ogghiu ri sciuri uagliu di pricò, pricò, pericò Clinopodium nepeta (L.) Kuntze (CORISSIA S/0149) Hyssopus officinalis L. (CORISSIA - S/0370) Marrubium vulgare L. (CORISSIA - S/0307) Hypericum perforatum L. (CORISSIA - S/0296) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Plant uses* Preparation methods Number of citations Flower Burns, bruises, contusions, wounds Oil 4 Flower Burns, bruises, contusions, wounds Oil 11 nipitedda Aerial part, leaf Insect bites Cataplasm, mashed leaf 4 CAL (3); CAM (2); LAT (2); SIC (2) soppiu, soppio, issopo Aerial part Cough, bronchitis Decoction 7 CAM (1); FRI (1); PIE (3) CYP (1); POR (1) marrobbio Aerial part, leaf Bronchitis, cough Infusion 4 Aerial part, leaf Pimples, wounds Cataplasm 3 Aerial part Digestive, refreshing Decoction, infusion 3 Aerial part Digestive, refreshing Infusion 2 Haematomas, wounds, swelling Digestive, refreshing Cataplasm, decoction 15 Cataplasm, decoction 5 Aerial part Liver disorders Decoction 2 Leaf Digestive, refreshing Cataplasm 2 ABR (1); CAM (3); LAT (1); MOL (1); SIC (2); TUS (1) Leaf Headache, sedative Decoction 1 APU (1); BAS (1); CAM (1); LAT (1); SIC (1) CAM (3); SAR (1); SIC (4) C H POR (1); SPA (1) APU (1); ABR (2); BAS CYP (2); GRE (1); MAC (2); CAM (4); FRI (2); (1); POR (2); SPA (2); LAT (1); LIG (1); LOM TUR (1) (2); MAR (1); PIE (2); SAR (2); SIC (5); TUS (3) Common Lamiaceae Mentha aquatica L. (CORISSIA - S/0236) amenta Mentha pulegium L. (CORISSIA - S/0229) discordio, scordio Aerial part, leaf Aerial part, leaf Mentha suaveolens Ehrh. (CORISSIA - S/0294) amintastru C L APU (2); CAL (1); CAM CYP (1); GRE (1); MOR (1); LIG (1); SAR (1); SIC (2); TUN (1) (3); TRE (2) Common ABR (1); APU (1); BAS (1); SAR (2) C L CAL (1); CAM (1); MAR ALB (1); ALG (1); MOR (2) Common (2); SPA (1) CAM (3); LAT (1); SAR (3); SIC (2); TRE (1); TUS (1) C L POR (1) SPA (1); POR (1) BAS (1); SIC (1) ABR (1); CAM (3); LIG (1); LAT (1); MOL (1); SIC (4); TUS (2) ALG (1); CYP (1); MOR (3); POR (1); SPA (3); TUR (3) CYP (1); TUN (1) Table 2h Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Rosmarinus officinalis L. (CORISSIA - S/0357) rosamarinu Flower, leaf Asthma Infusion 21 C H CYP (2); GRE (1); POR (1); SPA (4); TUR (4) Salvia officinalis L. (CORISSIA - S/0084) sarvia Leaf Digestive Decoction 6 C H Leaf Teeth cleaning , toothache Decoction, direct application 7 C L Leaf Cold, cough, bronchitis, febrifuge Decoction 3 C L ABR (2); APU (3); BAS (4); CAM (2); LAT (1); SAR (2); SIC (2); TUS (1) Common ABR (1); CAL (2); CAM (3); LAT (1); LIG (2); MOL (1); SIC (1); SAR (1); TUS (3) Common APU (1); BAS (1); LAT (1); LIG (2); MOL (1); SIC (3); TUS (1) Common ABR (2); BAS (1); MAR (1); MOL (1); SAR (2); SIC (2); TUS (2) Aerial part Wounds Decoction 2 ABR (3); CAL (1); LAT (3); LIG (1); MAR (1); SIC (1) SPA (1) Aerial part Renal colics Decoction 1 LIG (1); SIC (2) Haematomas, wounds Decoction 4 ABR (1); MAR (1); SIC (1) Headache Decoction 5 SIC (1) Digestive, refreshing Decoction 18 C H ABR (1); APU (2); BAS ALG (1); CYP (1); GRE (5); CAL (1); CAM (3); (1); MOR (1); SPA (4); LAT (1); LIG (3); LOM TUR (3) (1); MOL (1); SAR (3); SIC (9); TUS (4) Common Fruit Rheumatic pains Fruit macerated in oil 2 C L CAL (1); CAM (1); LIG (1); SIC (2) Common Aerial part Bronchitis, cough Decoction 2 Aerial part Digestive, refreshing Decoction 2 Salvia verbenaca L. (CORISSIA - S/0117) Teucrium scordium L. (CORISSIA - S/0024) centiligaddu discordio, scordio Aerial part Thymbra capitata (L.) Cav. sataredda (CORISSIA - S/0391) masculina, timu Lauraceae Laurus nobilis L. (CORISSIA - S/0218) Flower, leaf addagaru, addauru Leaf Malvaceae Lavatera agrigentina Tineo marva di luppina (CORISSIA - S/0238) SIC (2) ALB (1); ALG (1); POR (1); SPA (1); TUR (1) ALB (1); EGY (1); MOR (2); POR (1); SPA (1); TUR (1) ALG (1); EGY (1); MOR (2); POR (1); SPA (1); TUR (1) CYP (1); GRE (1); MOR (1) GRE (1); LEB (1); TUN (1) Table 2i Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Malva nicaeensis All. (CORISSIA - S/0391) Malva sylvestris L. (CORISSIA - S/0227) Used plant part(s) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Plant uses* Preparation methods Number of citations marbuni sarvaggiu Leaf Rheumatic pains Decoction 21 SIC (1) marva Flower, leaf Digestive, anti-inflammatory gastrointestinal system Decoction 2 Aerial part, flower, leaf Gingivitis, toothache Decoction, infusion 21 C L ABR (3); APU (1); BAS CYP (2); EGY (1); GRE (3); CAL (2); CAM (3); (1); POR (1); SPA (3); FRI (1); LAT (2); LIG (3); TUN (1); TUR (4) MAR (2); MOL (3); PIE (1); SAR (3); SIC (8); TUS (4); UMB (2) Common CAL (1); MOL (1); SIC (1) Aerial part, flower, leaf Digestive, anti-inflammatory gastrointestinal system Decoction, infusion 41 C H CAL (1); SIC (1) Aerial part, flower, leaf Enema preparation, fistulas Decoction, infusion 3 paparina Fruit, seed Sedative Infusion, toxic 5 C H BAS (4); CAM (4); LAT (1); LIG (3); LOM (1); MOL (1); SAR (1); SIC (10); TUS (2) Common CYP (1); MOR (1); TUR (3) paparina Fruit Sedative Infusion, toxic 2 ABR (1); APU (1); BAS (3); CAL (1); CAM (1); SAR (1); SIC (1); TRE (1); TUS (1) ALB (1); GRE (1); MOR (2); SPA (2); TUR (1) erva maisa, pilusedda Leaf Hyperhidrosis of the feet Direct application 6 erva maisa Kickxia spuria ( L.) Dumort. (CORISSIA - S/0216) Plantago major L. centuniervi (CORISSIA - S/0305) Leaf Hyperhidrosis of the feet Direct application 2 SIC (1) Leaf Pimples Direct application 3 BAS (3); CAM (4); LIG ALB (2); CYP (1); GRE (1); LOM (1); MOL (1); (1); POR (3); TUR (1) SAR (1); SIC (2); TUS (3) Common Malva trimestris (L.) Salisb. marva, marba (CORISSIA - S/0256) Papaveraceae Papaver rhoeas L. subsp. rhoeas (CORISSIA S/0265) Papaver somniferum L. (CORISSIA - S/0033) Plantaginaceae Kickxia elatine (L.) Dumort. (CORISSIA S/0342) C LEB (1) H Table 2j Table 2 (continued) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Plant uses* Preparation methods Number of citations Poaceae Arundo donax L. (CORISSIA - S/0233) canna Stem Haemostatic, wounds Direct application 2 BAS (5); CAM (1); LIG (1); SAR (2); SIC (4); TUS (1) Common Avena fatua L. (CORISSIA - ina sarvaggia S/0243) Aerial part Haemostatic, wounds Cataplasm, leaf juice 2 MAR (1); SIC (2) Cynodon dactylon (L.) gramigna, Pers. (CORISSIA - S/0337) ramigna Rhizome, root Diuretic Decoction 54 Polygonum aviculare L. (CORISSIA - S/0065) Aerial part Anti-inflammatory Decoction Aerial part Kidney stones centugruppa, centugruppa C H Common/similar use in other Mediterranean countries ABR (2); APU (2); BAS (1); CAL (1); CAM (3); LAT (2); LIG (2); MAR (1); MOL (3); PIE (1); SAR (2); SIC (11); TUS (4) Common CYP (1); MOR (2); POR (1); TUN (1); TUR (2) 2 ABR (1); LAT (1); MOL (1); SIC (1); TUS (1) LEB (1); POR (1); TUR (1) Decoction 2 CAM (1); SIC (2); GRE (2); POR (1); SPA Common (1); TUR (2) ABR (1); APU (1); BAS TUR (1) (1); CAM (2); LAT (1); LIG (2); SAR (2); TUS (3) Common Rumex crispus L. (CORISSIA - S/0333) lingua di cane, lingua ri cani Aerial part Haematomas, wounds Direct application 2 Rumex pulcher L. (CORISSIA - S/0021) lappazzu Leaf Abscesses, pimples Direct application 2 CAL (1); SIC (1) pilapordio Root Constipation Decoction, finely chopped root 2 SIC (5) Root Pneumonia in horses and cattles (veterinary use) Direct application 1 SIC (3) Aerial part Wounds Cataplasm, decoction 7 APU (1); BAS (1); FRI (1); SIC (1); VEN (1) Polypodiaceae Polypodium australe Fèe (CORISSIA - S/0019) Ranunculaceae Helleborus bocconei Ten. raricchiu subsp. siculus (Schinffner) Merxm. et Podl. (CORISSIA - S/0348) TUR (1) Rosaceae Agrimonia eupatoria L. (CORISSIA - S/0102) erva crimonia, lacrimonia ALB (1); POR (1) Table 2k Table 2 (continued) Family, scientific name, voucher specimen code Vernacular name Used plant part(s) Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Plant uses* Preparation methods Number of citations Crataegus monogyna Jacq. azzarualu Flower, fruit (CORISSIA - S/0344) sarvaggiu, spinapuci, zinzuli Hypotensive Decoction 2 ABR (1); FRI (2); LIG (1); GRE (1); MAC (1); POR LOM (1); PIE (1); SAR (1); SPA (1) (1); SIC (1); TUS (1) Common Rosa canina L. (CORISSIA - S/0061) rosa sarvaggia, rosa servaggia Flower Eye infection, eye wash Decoction 2 ABR (1); BAS (1); CAM ALB (2); GRE (1); SPA (1); LAT (1); LOM (1); (1) MOL (1); PIE (1); SIC (2); TUS (2) Rubus ulmifolius Schott (CORISSIA - S/0261) ruviatta, ruviatti Fruit, leaf Abscesses, pimples, wounds Direct application 18 Leaf, root Haemorrhoids Decoction 3 Leaf, branch Intestinal worms, stomach pain Decoction, fresh leaf 19 Leaf, branch Placenta expulsion in cattle and sheep following birth (veterinary use) Decoction 4 Aerial part, stem Aerial part Haemorrhoids Decoction 12 Wounds Decoction Root Digestive, refreshing Root Leaf Rutaceae Ruta chalepensis L. (CORISSIA - S/0153) Scrophulariaceae Verbascum sinuatum L. (CORISSIA - S/0180) ruta scuparina, tassu barbassu C H ABR (2); BAS (2); CAL POR (1); SPA (2) (2); CAM (5); LAT (3); MAR (1); MOL (3); SAR (1); SIC (6); TUS (2) Common SAR (1); SIC (1) C H APU (1); CAL (2); CAM ALG (1); CYP (1); JOR (2); LIG (1); SAR (2); SIC (1); POR (1); SPA (1); (11); TUS (2) Common TUR (1) C L SIC (3); TUS (1) GRE (1); MOR (1) 3 CAL (1); SIC (2) CYP (1); GRE (1) Decoction 13 LIG (2); SAR (2); SIC (1) SPA (1) Diuretic Decoction 1 CAL (1); CAM (1); LAT (1); LIG (1); SAR (2); SIC (3); TUS (1) Warts, toothache Cataplasm 5 ABR (1); SIC (4); TUS (1) SPA (1) Common Smilacaceae Smilax aspera L. (CORISSIA - S/0073) Solanaceae Hyoscyamus albus L. (CORISSIA - S/309) scuttidda, sarsa siciliana erva grassudda Table 2l Table 2 (continued) Family, scientific name, voucher specimen code Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Used plant part(s) Plant uses* Preparation methods Number of citations Leaf Rheumatic pains Cataplasm 2 SIC (3) spina santa Aerial part Digestive, refreshing Decoction, infusion 3 SIC (1) Mandragora autumnalis pampina di Bertol. (CORISSIA mennula S/0092) Solanum americanum Mill. sulatra (CORISSIA - S/0067) Aerial part, fruit Pimples, warts, wounds Cataplasm, toxic 3 SIC (6) Leaf Haemorrhoids Cataplasm 1 CAM (1); MAR (1); SAR MOR (2) (1); SIC (3) Lycium europaeum L. (CORISSIA - S/0166) Vernacular name Tamaricaceae Tamarix africana Poir. (CORISSIA - S/0211) vruca, vruchi Branch, leaf Skin inflammations, wounds Cataplasm, direct application 2 SAR (1); SIC (2) Tiliaceae Tilia americana L. (CORISSIA - S/0055) tiglio Flower Sedative Infusion 2 ABR (1); LAT (1); LIG (1); CAM (1); MAR (2); MOL (1); SIC (1); TUS (1) Typhaceae Typha angustifolia L. (CORISSIA - S/0190) buda Root Haemorrhoids Cataplasm 1 Leaf Wounds Direct application 1 Aerial part Burns, contusions, hematomas, wounds Cataplasm, decoction 12 C L Anti-dandruff Decoction 13 C H Urticaceae Parietaria judaica L. (CORISSIA - S/0085) Urtica dioica L. (CORISSIA - S/0260) erva di vientu ardicula, ferdica, Leaf arzicula, cardicula, ziculiedda, ardicula mascolina, ardicela, firdicula, artichi CYP (1); GRE (1); SPA (4); TUR (1) APU (2); CAL (1); CAM (2); SIC (2) ABR (1); BAS (1); CAL (1); LAT (1); LIG (2); MAR (2); SAR (2); SIC (7); TUS (3); UMB (1) Common APU (1); BAS (2); CAM (2); FRI (1); LOM (1); MAR (3); SIC (4) GRE (1); SPA (1) ALB (1); MOR (1); SPA (1); TUN (1); TUR (1) Table 2m Table 2 (continued) Family, scientific name, voucher specimen code Used plant part(s) Plant uses* Preparation methods Number of citations Status of the use in the study area Level of perceived Common/similar use in usefulness of other Italian regions species Common/similar use in other Mediterranean countries Leaf Anaemia Condiment 15 C L APU (1); BAS (1); MOL (1); SIC (1) CYP (1); GRE (1); MOR (1); SPA (3) Leaf Digestive, refreshing Decoction 17 C H ALB (1); MOR (1); TUR (1) Aerial part Digestive, refreshing Decoction 7 C L Aerial part Anti-inflammatory Decoction 2 ABR (3); BAS (2); LAT (3); LIG (1); LOM (1); MAR (1); MOL (2); PIE (1); SAR (3); SIC (3); TUS (3) ABR (1); CAL (1); CAM (1); MOL (1); SAR (1); SIC (1) CAL (1); SAR (1); SIC (1); TUS (2) Aerial part Digestive, refreshing Decoction 2 ABR (1); CAM (1); LAT (1); MOL (1); SAR (2); SIC (3); TUS (1); UMB (1) CYP (1); SPA (1) bibbina, birbina Leaf, root Haematomas, wounds Decoction 12 LAT (1); SAR (1); SIC (3); TUS (1) Common SPA (4); TUN (1) purrazzu Bulb Warts, boils Direct application 2 SAR (1) Skin inflammations Direct application 7 LAT (1); SAR (2); SIC (6); TUS (1) Vernacular name Urtica membranacea Poir. ardicula, ferdica ex Savigny (CORISSIA S/0392) Urtica urens L. (CORISSIA ardicula - S/0017) Verbenaceae Verbena officinalis L. (CORISSIA - S/118) Xanthorrhoeaceae Asphodelus cerasifer Gay (CORISSIA - S/0096) Asphodelus ramosus L. subsp. ramosus Viv.(CORISSIA - S/0133) purrazza, Root arvuluzzu, arbruzzu, ulivuzza MOR (1); SPA (1) * Description of the use, medicinal properties attributed to the plant, illness for which the species is used. Abbreviations Symbols: C - current use in the study region; H - high level of perceived usefulness; L - low level of perceived usefulness Italian regions: ABR - Abruzzo; APU - Apulia; BAS - Basilicata; CAL - Calabria; CAM - Campania; FRI - Friuli Venezia Giulia; LAT - Latium; LIG - Liguria; LOM - Lombardia; MAR - Marche; MOL - Molise; PIE - Piemonte and Valle d'Aosta; SAR - Sardinia; SIC - Sicily; TRE - Trentino Alto Adige; TUS - Tuscany; UMB - Umbria; VEN - Veneto Mediterranean countries: ALB - Albania; ALG - Algeria; CYP - Cyprus; GRE - Greece; EGY - Egypt; JOR - Jordan; LEB - Lebanon; MAC - Macedonia; MOR - Morocco; POR - Portugal; SPA - Spain; TUN - Tunisia; TUR Turkey References for the Italian regions: Common - according to Guarrera (2006) the use is common in several Italian regions ABR - Tamarro (1984); Guarrera (1987); De Simoni and Guarrera (1994); Leporatti and Corradi (2001); Guarrera (2005); Idolo et al. (2010) APU - Frigino et al. (1999); Maccioni et al. (2001); Bianchi and Gallifuoco (2004); De Mastro et al. (2004); Leporatti and Guarrera (2004); Guarrera and Leporatti (2007) BAS - Pieroni et al. (2002); Pieroni et al. (2004); Pieroni and Quave (2005); Guarrera et al. (2005b); Guarrera et al. (2006); Quave and Pieroni (2007); Quave et al. (2008); Montesano et al. (2012); Di Sanzo et al. (2013) Table 2n CAL - Barone (1963); Passalacqua et al. (2007); Leporatti and Impieri (2007) CAM - Antonone et al. (1988); De Feo et al. (1991); De Feo et al. (1992); De Feo et al. (1993); Scherrer et al. (2005); De Natale and Pollio (2007); De Natale et al . (2008); Guarino et al. (2008); Salerno and Guarrera (2008); Motti et al . (2009); Savo et al . (2011); Di Novella et al. (2013) FRI - Appi et al. (1979); Coassini Lokar and Poldini (1988) LAT - Guarrera (1994); Ciccodicola (1995); Guarrera (2005); Guarrera et al. (2004); Guarrera et al. (2005a); Idolo et al. (2010) LIG - Chiovenda-Bensi (1960); Gastaldo et al. (1978); Martini (1982); Maccioni et al. (1999); Maccioni et al. (2008); Maxia et al. (2008); Cornara et al. (2009) MAR - Pieroni et al . (2004); Guarrera et al . (2005) LOM - Vitalini et al. (2009); Vitalini et al. (2013) MAR - Guarrera (1981); Bellomaria (1982); Bellomaria and Lattanzi (1982); Bellomaria and Della Mora (1985); Leporatti et al. (1985a); Pieroni et al. (2004); Guarrera et al. (2005) MOL - Menale et al. (2006); Guarrera et al. (2008); Idolo et al. (2010); Di Tizio et al. (2012) PIE - Lomagno and Lomagno Caramiello (1970); Lomagno and Lomagno Caramiello (1977); Servettaz et al. (1979); Lomagno Caramiello et al. (1984); Longhi and Scanavino (1987); Sella et al. (1992); Pieroni and Giusti (2009); Mattalia et al. (2013) SAR - Atzei et al. (1991); Ballero and Fresu (1991); Ballero and Fresu (1993); Atzei et al. (1994); Bruni et al. (1997); Ballero et al. (2001); Palmese et al. (2001); Loi et al. (2004); Sanna et al. (2006); Signorini et al. (2008) SIC - Catanzaro (1970); Galt and Galt (1978); Barbagallo et al. (1979); Lentini (1987); Lentini and Mazzola (1988); Lentini et al. (1988); Lentini and Raimondo (1990); Raimondo and Lentini (1990a,b); Lentini and Aleo (1991); Ilardi and Raimondo (1992); Lentini and Amenta (1992); Lentini et al. (1994); Lentini et al. (1995); Lentini et al. (1997); Arcidiacono et al. (1999); Lentini (2000); Arcidiacono (2002); Arcidiacono et al. (2007); Lentini and Venza (2007); Grillo (2010); Aleo et al. (2011); Leto et al. (2013) TRE - Pedrotti and Bertoldi (1930); Cappelletti et al. (1981); Renzetti and Taiani (1988) TUS - Ferri (1977); Corsi and Pagni (1978); Pagni and Corsi (1979); Corsi et al. (1980); Bilia et al. (1990); Chiavoni et al. (1994); Mearelli and Tardelli (1995); Uncini Manganelli and Tomei (1995); Maccioni et al. (1997); Camangi and Uncini Manganelli (1999); Tomei et al. (1999); Uncini Manganelli and Tomei (1999); Uncini Manganelli et al. (2000); Pieroni (2000); Camangi et al. (2003) UMB - Leporatti et al. (1985b); Nardelli (1987); Ranfa et al. (2013) VEN - Cappelletti et al. (1979) References for Mediterranean countries: ALB - Pieroni et al. (2005); Gonzàlez-Tejero et al. (2008); Pieroni (2008) ALG - Gonzàles-Tejero et al. (2008); Pollio et al. (2008) CYP - Gonzàles-Tejero et al. (2008); Pollio et al. (2008); Karousou and Deirmentzoglou (2011); Lardos and Heinrich (2013) GRE - Hanlidou et al. (2004) EGY - Gonzàles-Tejero et al. (2008); AbouZid and Mohamed (2011) JOR- Pollio et al. (2008) LEB - El Beyrouthy et al. (2008) MAC – Pieroni et al. (2013b) MOR - Merzouki et al. (2000); Joaud et al. (2001); El-Hilaly et al. (2003); Gonzàles-Tejero et al. (2008) POR - Camejo-Rodrigues et al. (2003); Novais et al. (2004); Pollio et al. (2008); Neves et al.(2009) SPA - Vazquez et al. (1997); Blanco et al. (1999); Bonet et al. (1999); Akerreta et al. (2007); Gonzàles-Tejero et al. (2008); Pollio et al. (2008); Parada et al. (2009); Benitez et al. (2010); Calvo et al. (2011); Cavero et al. (2011a; 2011b) TUN - Leporatti and Ghedira (2009) TUR - Akalın and Alpınar (1994); Honda et al. (1996); Tuzlaci and Erol (1999); Yesilada et al. (1999); Tuzlaci and Tolon (2000); Tuzlaci and Eryasar-Aymaz (2001); Everest and Ozturk (2005); Kultur (2007); Pollio et al. (2008); Uysal (2008); Fakir et al. (2009); Ugulu et al. (2009); Cakilcioglu and Turkoglu (2010); Cakilcioglu et al. (2011); Gurdal and Kultur (2013); Tetik et al. (2013) Table 3 Table 3 List of wild medicinal plants most frequently cited and currently used by informants along with the Cultural Importance Index. Taxa Family Number of interview in which Frequency (%)* it was cited Cultural importance index (CI) Cichorium intybu s L. Athamanta sicula L. Malva trimestris (L.) Salisb. Cynodon dactylon (L.) Pers. Opuntia ficus indica (L.) Miller Sonchus oleraceus (L.) L. Urtica dioica L. Borago officinalis L. Senecio delphinifolius Vahl. Laurus nobilis L. Mentha pulegium L. Rubus ulmifolius Schott Asteraceae Apiaceae Asteraceae Poaceae Cactaceae Asteraceae Urticaceae Boraginacae Asteraceae Lauraceae Lamiaceae Rosaceae 62 57 57 55 48 42 36 25 24 21 21 20 0.23 0.28 0.28 0.23 0.21 0.17 0.19 0.21 0.11 0.09 0.09 0.09 *as percentage of citations on the total of 230 informants 26.96 24.78 24.78 23.91 20.87 18.26 15.65 10.87 10.43 9.13 9.13 8.70 Table 4 Table 4 Illness categories of wild medicinal plants in the Monti Sicani Regional Park with the associated Informant Consensus Factor. No. Illness categories 1 2 3 4 5 6 7 8 Articulary system diseases and traumatic injuries Skin diseases Gastrointestinal system diseases General health and metabolic disorders Infectious diseases, inflammations Urinary system diseases Respiratory system diseases Others*** Species in each category* Incidence (%)** Use reports Informant consensus factor (ICF) 30 17 26 15 8 11 8 11 23.81 13.49 20.63 11.90 6.35 8.73 6.35 8.73 174 69 347 108 112 290 44 66 0.83 0.76 0.93 0.87 0.94 0.96 0.84 0.85 * the same species may be listed in more than one illness category ** as percentage of records on the total of 126 records *** this category includes: cardiovascular system diseases, endocrinology and reproductive system disease, veterinary uses Table 5 Table 5 Comparison of ethnobotanicity index (EI) of the study area with those of other localities in Central-Southern Italy and the Iberian Peninsula. Total number of Regions species of the EI (%) References flora Italian regions Latium High Molise region (Molise) Acquapendente (Latium) Majella (Abruzzo) Maratea (Basilicata) Madonie Regional Park (Sicily) Mediterranean regions Pallars (Catalonia, Spain) Cabo de Gata (Andalusia, Spain) São Mamede (Portalegre, Portugal) Tràs-os-Montes (Chaves, Montalegre, Portugal) Cordoba (Anlalusia, Spain) Arrabida (Setùbal, Portugal) Pirineo Navarro (Spain) Monti Sicani Regional Park (Sicily, Italy) * data refer to the Guarrera et al. (2008) publication ** data refer to the Neves et al. (2009) publication 3228 800 1070 1700 1019 1500 8.36 6.00 5.42 5.23 3.83 6.16 Guarrera (1994*) Guarrera et al. (2008) Guarrera et al. (2005a) Guarrera (1987*) Guarrera et al. (2005b) Leto et al. (2013) 1500 1000 800 537 1641 1450 1822 850 29.10 25.30 23.10 16.00 8.80 8.28 5.05 12.70 Agelet and Vallès (2001; 2003a,b) Martinez-Lirola et al. (1996) Camejo-Rodrigues (2003) Neves et al. (2009) Casana (1993)** and Galàn (1993)** Novais et al. (2004) Akerreta et al. (2007) Present study Figure 1 Click here to download high resolution image Figure 2 Click here to download high resolution image
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