Hot Topics in renal transplantation

Course Aim
This Meeting traditionally brings together investigators
and clinicians with foremost experience in kidney
transplantation, to discuss topics related to kidney
transplant care. Failure of a kidney transplant is still
a major problem after kidney transplantation, in spite
of recent immunosuppressive protocols and focus
of clinical management addressing at prolonging
long-term graft survival. The learning objectives of
this course include the recognition of clinical and
pathological features, as well as the prevention and
management of long term kidney transplants.
Some of the major issues related to both the early
and late post transplant course, including acute and
chronic antibody mediated rejection, the endothelial
damage induced by circulating anti-HLA and nonHLA antibodies and by HUS, an update of the most
recent findings on kidney transplant pathology on
will be discussed. The interdisciplinarity of workers,
the periodical nature of these meetings and the
friendly relationships among the participants make
them a unique opportunity to discuss freely and in a
uninformal context.
CISEF Germana Gaslini
Course Venue
Registration
CISEF G. Gaslini - Badia Benedettina della Castagna
Via Romana della Castagna, 11 A
16148 Genova Quarto - Italy
80 participants will be admitted according to the order
of arrival of the applications.
How to reach the Venue
Completed application should be submitted to the
Scientific Secretariat. The deadline for receipt of
applications is March 31, 2014. Up to 80 participants
will be notified of acceptance by mid April. Cancellations
will be filled from a list of alternates.
Scientific Secretariat
Free attendance
856-83810
Italian CME credits will be available for medical doctors
(disciplines: surgery, nephrology, pediatrics). The
participant’s CME credit will be dependent upon
completion and return of a content specific quiz to
test the knowledge after the CME activity, and the
satisfaction form.
Official language
The official language of the Congress is English.
No simultaneous translation will be available.
Serena Bagnasco
Department of Pathology, Johns Hopkins University
School of Medicine - Baltimore, USA
Dr.ssa Kristina Cosulich
Di.M.I., University of Genoa and Clinic of Nefrology,
Dialysis and Transplantation IRCSS IST
A.O.U. San Martino, Genoa, Italy
Fabrizio Ginevri
Nefrology, Dialysis and Transplantation,
Istituto Giannina Gaslini Ospedale Pediatrico IRCCS
Genoa, Italy
Centro Internazionale di Studi e Formazione (C.I.S.E.F.)
"Germana Gaslini"
Via Romana della Castagna, 11A
16148 Genova, Italy
ph. +39 010 5636878 - fax: +39 010 3071591
e.mail: [email protected]
www.cisef.org
Augusto Tagliamacco
Transplant Immunology Research Laboratory - Di.M.I.,
University of Genova, and IRCSS IST A.O.U. San Martino
Genoa, Italy
Endorsement requested
CME accreditation
Conference secretariat
and information
Giacomo Garibotto
Endothelial injury
Genoa, April 12th 2014
General information
Plane: From the International Airport C. Colombo, shuttle
bus n. 100 (runs every 20 minutes) takes you to Genova
Brignole railway station in 30 minutes.
Train: Participants arriving to Genova by train should bear
in mind that there are two major stations in the city:
Genova-Brignole and Genova-Principe. Not all the trains
- particularly from northern Italy (e.g., Milano) - pass
through Genova-Brignole: therefore, make sure that your
train does indeed stop at Genova-Brignole. From Genova
Brignole railway station, take bus n. 17 and get off in
Corso Europa, in front of the AC Hotel / Coop supermarket.
Car: Motorway exit Genova-Nervi, take Corso Europa
westwards, take the overpass and drive eastwards, pass
Hotel AC and ESSO gas station on the right, after 50 mt.
turn right into Via Romana della Castagna, go straight 80
mt., enter the gate on the right leaving the church on the
left and follow signs for parking.
Hot Topics
in renal transplantation
Provider Nazionale Accreditato ECM n. 856
Certificazione ISO 9001:2008
The Organizers wish to acknowledge the generous support of
UNIVERSIT¸ DEGLI STUDI
DI GENOVA
Scientific Program
08.30 Registration
09.00 Introduction
Centro Internazionale
di Studi e Formazione
Germana Gaslini
Direttore: Antonio Infante
Faculty
Serena M. Bagnasco
Department of Pathology, Johns Hopkins University School of Medicine
Baltimore, Maryland, USA
Luigi Biancone
Division of Nephrology, Dialysis, and Transplantation, Department of Medical Science,
San Giovanni Battista Hospital and University of Turin, Turin, Italy
Patrizia Comoli
Ist SESSION
Endothelial injury in the renal graft
Chair: Domenico Palombo (Genoa), Andrea Gianelli (Genoa)
Deparment of Hematology and Oncology, Pediatric Research Laboratories, Fondazione IRCCS
Policlinico San Matteo - Pavia, Italy
Thomas Fehr
Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
Iris Fontana
09.15 Anti-HLA antibodies
Giuseppe Piccolo (Milano)
09.45 Non-HLA antibodies
Annette Jackson (Baltimore, USA)
10.15 Graft Cells as targets for DSA: not only endothelial cells
Luigi Biancone (Torino)
10.45 Vascular lesions in the renal graft
Serena M. Bagnasco (Baltimore, USA)
11.15 Coffee Break
Kidney Transplant Unit IRCSS IST Azienda Ospedale-Università San Martino, Genoa, Italy
Gian Marco Ghiggeri
Nefrology, Dialysis and Transplantation, Istituto Giannina Gaslini Ospedale Pediatrico IRCCS,
Genoa, Italy
Andrea Gianelli
Forensic Medicine and Transplant Coordination,
IRCSS IST Azienda Ospedale-Università San Martino, Genoa, Italy
Annette Jackson
Assistant Professor, Department of Medicine, Johns Hopkins University School of Medicine,
Baltimore, Maryland, USA
Arcangelo Nocera
Transplant Immunology Research Laboratory, Department of Internal Medicine -DIMI, University
of Genova, Genoa, Italy
Domenico Palombo
IInd SESSION
Endothelial injury in the renal graft (Part 2)
Chair: Iris Fontana (Genoa), Patrizia Comoli (Pavia)
Head, Vascular and Endovascular Surgery, Università degli Studi di Genova and
RCSS IST AOU San Martino-IST Genoa, Italy
Ernesto Paoletti
Nephrology, Dialysis, Transplantation Clinic IRCSS IST San Martino, Genoa, Italy
Giuseppe Piccolo
11.30 How to translate immunological tolerance into clinically applicable protocols?
Thomas Fehr (Zurich, CH)
12.00 HUS update for the transplant nephrologist
Piero Ruggenenti (Bergamo)
12.30 Desensitisation protocols
Arcangelo Nocera, Augusto Tagliamacco (Genoa)
13.00 Lunch
14.00 CLINICO-PATHOLOGICAL DISCUSSION:
S. Bagnasco, L. Racusen, G. Garibotto, A. Sementa, F. Ginevri, JL. Ravetti, D. Rolla, G. Salvidio
16:00 Special Lecture
Update from the 2013 Banff Meeting
Lorraine Racusen (Baltimore, USA)
16.40 How to handle with proteinuria in kidney transplant patients?
Ernesto Paoletti (Genoa)
17.10 Vascular damage and hyperuricemia in the transplant patient
Francesca Viazzi (Genoa)
17.40 Conclusions
Transplantation Immunology, Fondazione IRCCS Ca` Granda Ospedale Maggiore Policlinico,
Milano, Italy
Lorraine Racusen
Department of Pathology, Johns Hopkins University School of Medicine
Baltimore, Maryland, USA
Jean Louis Ravetti
Division of Pathology IRCSS IST AOU San Martino-IST Genoa, Italy
Davide Rolla
Nephrology, Dialysis, Transplantation Clinic IRCSS IST San Martino, Genoa, Italy
Piero Ruggenenti
Division of Nephrology and Dialysis, Azienda Ospedaliera Ospedali Riuniti di Bergamo, Italy
Gennaro Salvidio
Nephrology, Dialysis, Transplantation Clinic IRCSS IST San Martino, Genoa, Italy
Angela Sementa
Department of Pathology, Istituto Giannina Gaslini Ospedale Pediatrico IRCCS, Genoa, Italy
Augusto Tagliamacco
Transplant Immunology Research Laboratory -DIMI, University of Genova,
and IRCSS IST AOU San Martino-IST Genoa, Italy
Francesca Viazzi
Department of Internal Medicine, Università degli Studi di Genova and
IRCSS IST AOU San Martino-IST Genoa, Italy

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