VALENZA F_CV ingl ottobre 2014 - Università degli Studi di Milano

Valenza Franco, MD
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CURRICULUM VITAE
IDENTIFICATION
Cognome
Nome
Data di nascita
VALENZA
FRANCO
3 marzo 1965
RESEARCH ACTIVITY
Coordinator and leader of a multidisciplinary research team composed of anesthesiologists,
surgeons, nurses, residents in anesthesia and intensive care, undergraduated and graduated
medical students, biologists and technicians dedicated to the investigation of acute lung injury in
the settings of organ donation and lung transplantation.
Principal Investigator of
EXPERIMENTAL RESEARCH PROJECTS (small-large animal and cell culture models) on:
Lung preservation and regeneration strategies for lung transplantation including Ex-vivo lung
perfusion (EVLP), Multi-organ donor treatment, Lung transplantation, Ventilator induced lung
injury, Hypoxia, Metabolism and energy failure, Cardio-respiratory consequences of abdominal
hypertension
and
CLINCIAL RESEARCH PROJECTS on:
Ex-vivo lung perfusion (EVLP) for clinical lung transplantation, Care of the multi-organ donor
(multicenter investigations), Mechanical ventilation during anesthesia, Peri-operative conduct of
anesthesia in obese subjects, Abdominal hypertension and acute lung injury.
SCIENTIFIC PUBLICATIONS
Peer reviewed papers
Valenza F, Coppola S, Froio S, Ruggeri MG, Fumagalli J, Villa AM, Rosso L, Mendogni P, Conte G,
Lonati C, Carlin A, Leonardi P, Gatti S, Stocchetti N and Gattinoni L. A standardized model of brain
death, donor treatment, and lung transplantation for studies on organ preservation and
reconditioning. Intensive Care Medicine Experimental. DOI 10.1186/2197-425X-2-12. Epub 2014,
June 10
Valenza F, Rosso L, Coppola S, Froio S, Palleschi A, Tosi D, Mendogni P, Salice V, Ruggeri GM,
Fumagalli J, Villa A, Nosotti M, Santambrogio L, Gattinoni L. Ex vivo lung perfusion to improve
donor lung function and increase the number of organs available for transplantation. Transpl Int.
2014 Jun;27(6):553-61. doi: 10.1111/tri.12295. Epub 2014 Apr 4.
Akoumianaki E, Maggiore SM, Valenza F, Bellani G, Jubran A, Loring SH, Pelosi P, Talmor D, Grasso
S, Chiumello D, Guérin C, Patroniti N, Ranieri VM, Gattinoni L, Nava S, Terragni PP, Pesenti A, Tobin
M, Mancebo J, Brochard L. The application of esophageal pressure measurement in patients with
respiratory failure. Am J Respir Crit Care Med. 2014 Mar 1;189(5):520-31.
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Valenza Franco, MD
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Lonati C, Carlin A, Leonardi P, Valenza F, Bosari S, Catania A, Gatti S. Modulatory effects of NDPMSH in the regenerating liver after partial hepatectomy in rats. Peptides. 2013 Dec;50:145-52.
Valenza F, Froio S, Coppola S, Vagginelli F, Tiby A, Marenghi MC, Mozzi E, Roviaro GC, Gattinoni L.
Preoperative changes of forced vital capacity due to body position do not correlate with
postoperative respiratory function in obese subjects. Minerva Anestesiol. 2013 Apr;79(4):342-8.
Epub 2013 Jan 31.
Valenza F, Riggeri GM, Froio S, Coppola S, Gattinoni L. Old and new strategies to preserve the lung
before transplantation. Organs, tissues and cells 15 (2), 109-114
Valenza F, Pizzocri M, Salice V, Chevallard G, Fossali T, Coppola S, Froio S, Polli F, Gatti S, Fortunato
F, Comi GP, Gattinoni L. Sodium bicarbonate treatment during transient or sustained lactic
acidemia in normoxic and normotensive rats. PLoS One. 2012;7(9):e46035. doi:
10.1371/journal.pone.0046035. Epub 2012 Sep 28.
Porro GA, Valenza F, Coppola S, Froio S, Benazzi E, De Fazio N, Santambrogio L, D'Armini AM, Loy
M, Ravini M, Lucianetti A, Moretti MP, Vesconi S, Scalamogna M, Gattinoni L. Use of the Oto lung
donor score to analyze the 2010 donor pool of the Nord Italia Transplant program. Transplant
Proc. 2012 Sep;44(7):1830-4.
Valenza F, Rosso L, Gatti S, Coppola S, Froio S, Colombo J, Dossi R, Pizzocri M, Salice V, Nosotti M,
Reggiani P, Tosi D, Palleschi A, Pappalettera M, Ferrero S, Perazzoli A, Costantini D, Scalamogna M,
Rossi G, Colombo C, Santambrogio L, Gattinoni L. Extracorporeal lung perfusion and ventilation to
improve donor lung function and increase the number of organs available for transplantation.
Transplant Proc. 2012 Sep;44(7):1826-9.
Parotto M, Valenza F, Ori C, Spieth PM. Minimally invasive versus open oesophagectomy for
oesophageal cancer. Lancet. 2012 Sep 8;380(9845):884
Valenza F, Rosso L, Coppola S, Froio S, Colombo J, Dossi R, Fumagalli J, Salice V, Pizzocri M, Conte
G, Gatti S, Santambrogio L, Gattinoni L. β-adrenergic agonist infusion during extracorporeal lung
perfusion: effects on glucose concentration in the perfusion fluid and on lung function. J Heart
Lung Transplant. 2012 May;31(5):524-30
Valenza F, Rosso L, Salice V., Umbrello M, Conte G, Stanzi A, Colombo J, Gatti S, Santambrogio L,
Iapichino G, and Gattinoni L. The consumption of glucose during ex vivo lung perfusion correlates
with lung edema. Transplantation Proceedings 2011; May;43(4):993-6.
Carlesso E, Maiocchi G, Tallarini F, Polli F, Valenza F, Cadringher P, Gattinoni L. The rule regulating
pH changes during crystalloid infusion. Intensive Care Med. 2011 Mar;37(3):461-8
Valenza F, Chevallard G, Fossali T, Salice V, Pizzocri M, Gattinoni L.Management of mechanical
ventilation during laparoscopic surgery. Best Pract Res Clin Anaesthesiol. 2010 Jun;24(2):227-41.
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Valenza Franco, MD
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Valenza F, Fagnani L, Coppola S, Froio S, Sacconi F, Tedesco C, Maffioletti M, Pizzocri M, Salice V,
Ranzi ML, Marenghi C, Gattinoni L. Prevalence of endotoxemia after surgery and its association
with ICU length of stay.Crit Care. 2009 Jun 29;13(3):R102.
Chiumello D, Carlesso E, Cadringher P, Caironi P, Valenza F, Polli F, Tallarini F, Cozzi P, Cressoni M,
Colombo A, Marini JJ, Gattinoni L. Lung stress and strain during mechanical ventilation for acute
respiratory distress syndrome. Am J Respir Crit Care Med. 2008 Aug 15;178(4):346-55. Epub
2008 May 1.
Valenza F, Vagginelli F, Tiby A, Francesconi S, Ronzoni G, Guglielmi M, Zappa M, Lattuada E,
Gattinoni L. Effects of the beach chair position, positive end-expiratory pressure, and
pneumoperitoneum on respiratory function in morbidly obese patients during anesthesia and
paralysis. Anesthesiology. 2007;107:725-32
Wauters J, Wilmer A, Valenza F. Abdomino-thoracic transmission during ACS: facts and figures.
Acta Clin Belg Suppl. 2007;(1):200-5.
Valenza F, Chevallard G, Porro GA, Gattinoni L. Static and dynamic components of esophageal and
central venous pressure during intra-abdominal hypertension. Crit Care Med. 2007
Jun;35(6):1575-81.
Gattinoni L, Caironi P, Valenza F, Carlesso E. The role of CT-scan studies for the diagnosis and
therapy of acute respiratory distress syndrome. Clin Chest Med. 2006 Dec;27(4):559-70;
Valenza F, Aletti G, Fossali T, Chevallard G, Saconi F, Irace M, Gattinoni L. Lactate as a marker of
energy failure in critically ill patients: an hypothesis. Crit Care. 2005;9(6):588-93
Gattinoni L, Chiumello D, Cressoni P, Valenza F. Pulmonary computer tomography and adult
respiratory sindrome. Swiss med Wkly. 2005 Mar 19;135(11-12):169-74
Valenza F, Ronzoni G, Perrone L, Valsecchi M, Sibilla S, Nosotti M, Santambrogio L, Cesana MB,
Gattinoni L. Positive end-expiratory pressure applied to the dependent lung improves oxygenation
and respiratory mechanics in patients with high FEV1. Eur J Anaesthesiol. 2004 Dec;21(12):938-43
Valenza F, Guglielmi M, Maffioletti M, Tedesco C, Maccagni P, Fossali T, Alestti G, Porro GA, Irace
M, Carlesso E, Carboni N, Lazzerini M Gattinoni L. Prone position delays the progression of
ventilator-induced lung injury in rats: does lung strani play a role? Crit Care Med. 2005
Feb;33(2):361-7
Valenza F, Irace M, Guglielmi M, Gatti N, Bottini N, tedesco C, Maffioletti M, Taccagni P, Fossali T,
Aletti G, Gattinoni L. Effects of continuous negative extra-abdominal pressure on cardiorespiratory
function during abdominal hypertension: an experimental study. Intensive Care Med. 2005
Jan;31(1)105-11. Epub 2004 Oct 26
Gattinoni L, Chiumello D, Carlesso E, Valenza F. Bench-to-bedside review: chest wall elastance in
acute lung injury/acute respiratory distress syndrome patients. Crit Care. 2004 Oct;8(5):350-5.
Epub 2004 May 7.
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Valenza Franco, MD
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Gattinoni L, Carlesso E, Valenza F, Chiumello D, Caspani ML. Acute respiratory distress syndrome,
the critical care paradigm: what we learned and what we forgot. Curr Opin Crit Care. 2004
Aug;10(4):272-8.
Quintel M, Pelosi P, Caironi P, Meinhardt JP, Luecke T, Herrmann P, Taccone P, Rylander C,
Valenza F, Carlesso E, Gattinoni L. An increase of abdominal pressure increases pulmonary edema
in oleic acid-induced lung injury. Am J Respir Crit Care Med. 2004 Feb 169(4);534-41. Epub 2003
Dec 11.
Gattinoni L, Vagginelli F, Carlesso E, Taccone P, Conte V, Chiumello D, Valenza F, Caironi P, Pesenti
A; For the Prone-Supine Study Group. Decrease in PaCO2 with prone position is predictive of
improved outcome inacute respiratory distress syndrome. Crit Care Med. 2003 Dec;31(12):272733.
Gattinoni L, Carlesso E, Cadringher P, Valenza F, Vagginelli F, Chiumello D. Physical and biological
triggers of ventilator-induced lung injury and its prevention. Eur Respir J Suppl. 2003 Nov;47:15s25s.
Valenza F, Bottino N, Canavesi K, Lissoni A, Alongi S, Losappio S, Carlesso E, Gattinoni L. Intraabdominal pressure may be decreased non-invasively by continuous negative extra-abdominal
pressure (NEXAP). Intensive Care Med. 2003 Nov;29(11):2063-7. Epub 2003 Oct 07.
Valenza F, Guglielmi M, Irace M, Porro GA, Sibilla S, Gattinoni L. Positive end-expiratory pressure
delays the progression of lung injury during ventilator strategies involving high airway pressure
and lung overdistention. Crit Care Med. 2003 Jul;31(7):1993-8.
Sibilla S, Tredici S, Porro A, Irace M, Guglielmi M, Nicolini G, Tredici G, Valenza F, Gattinoni L. Equal
increases in respiratory system elastance reflect similar lung damage in experimental ventilatorinduced lung injury. Intensive Care Med. 2002 Feb;28(2):196-203. Epub 2002 Jan 12.
Valenza F, Sibilla S, Porro GA, Brambilla A, Tredici S, Nicolini G, Mieloso M, Tredici G, Gattinoni L.
An improved in vivo rat model for the study of mechanical ventilatory support effects on organs
distal to the lung. Crit Care Med. 2000 Nov;28(11):3697-704.
Catania A, Cutuli M, Garofalo L, Airaghi L, Valenza F, Lipton JM, Gattinoni L. Plasma concentrations
and anti-L-cytokine effects of alpha-melanocyte stimulating hormone in septic patients. Crit Care
Med. 2000 May;28(5):1403-7.
Valenza F. [Mechanical ventilation during thoracic anesthesia] Minerva Anestesiol. 1999
May;65(5):263-6.
Pelosi P, Tubiolo D, Mascheroni D, Vicardi P, Crotti S, Valenza F, Gattinoni L. Effects of the prone
position on respiratory mechanics and gas exchange during acute lung injury. Am J Respir Crit Care
Med. 1998 Feb;157(2):387-93.
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Valenza Franco, MD
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Aaron SD, Valenza F, Volgyesi G, Mullen JB, Slutsky AS, Stewart TE.Inhibition of exhaled nitric oxide
production during sepsis does not prevent lung inflammation. Crit Care Med. 1998 Feb;26(2):30914.
Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS. Injurious ventilatory strategies increase
cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest. 1997 Mar
1;99(5):944-52.
Gattinoni L, Pelosi P, Crotti S, Valenza F. Effects of positive end-expiratory pressure on regional
distribution of tidal volume and recruitment in adult respiratory distress syndrome. Am J Respir
Crit Care Med. 1995 Jun;151(6):1807-14.
Stewart TE, Valenza F, Ribeiro SP, Wener AD, Volgyesi G, Mullen JB, Slutsky AS. Increased nitric
oxide in exhaled gas as an early marker of lung inflammation in a model of sepsis. Am J Respir Crit
Care Med. 1995 Mar;151(3 Pt 1):713-8.
Editorials, Letters
Parotto M, Valenza F, Ori C, Spieth PM. Minimally invasive versus open oesophagectomy for
oesophageal cancer. Lancet. 2012 Sep 8;380(9845):884
Valenza F. Do recruitment maneuvers simply improve oxygenation? Crit Care. 2010 Jul
1;14(4):173.
Valenza F. The further back, the further forward. Intensive Care Med. 2009 May;35(5):958
Valenza F, Gattinoni L. Beach chair position: Is it really feasible in laparoscopic procedures? Reply
Anesthesiology. 2008; 108(6): 1153-1154
International book chapters
Valenza F, Fumagalli J, Salice V, Gattinoni L. Lung reconditioning. (2014) In: ECMO - Extracorporeal
Life Support in Adults. Sangalli F, Patroniti N and Pesenti A (Ed). Springer: pp 337-342
Valenza F, Parotto M, Gattinoni L. Respiratory Illness, Inflammatory Markers. (2012) In:
Encyclopedia of Intensive Care Medicine. Springer Berlin Heidelberg. pp:1992-1996
Langer T, Valenza F, Caironi P. Urine Electrolytes and Acid Base. (2012) In: Encyclopedia of
Intensive Care Medicine. Springer Berlin Heidelberg.pp: 2368-2370
Valenza F, Frank JA, Imai Y, Slutsky AS: Pathogenesis of ventilator-induced lung injury. (2010) In:
LungBiology in Health and Disease: Acute Respiratory Distress Syndrome, 2nd edition, Volume 233.
Choi AMK (Ed). Informa Healthcare USA, Inc., New York City: pp 109-145.
Gattinoni L, Valenza F, Carlesso E. ‘Adequate’Hemodynamics: A Question of Time? (2005) In:
Functional hemodynamic monitoring. Springer Berlin Heidelberg. pp 69-86
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Valenza Franco, MD
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Gattinoni L, Pelosi P, Brazzi L, Valenza F. (1999 1st ed, 2003 2nd ed). Acute respiratory distress
syndrome. In: Comprehensive respiratory medicine. (R. Albert, S. Sapiro, J. Jett, editors). pp 69.169.16
Gattinoni L, Pelosi P, Valenza F, Mascheroni D. (1994). Patient positioning in acute respiratory
failure. In Principles and Practice of Mechanical Ventilation. M.J. Tobin (Ed.). New York: Mc Graw
Hill, Inc.: pp. 1067-1076.
TEACHING ACTIVITY
In charge of the methodological and professional training of undergraduated and graduated
medical students, and of students training in anesthesia and intensive care, including supervision
and direct responsibility for 28 medical doctor degrees thesis and 9 specialty thesis in anesthesia
and intensive care, University of Milan, Faculty of Medicine.
In charge of a number of courses of Anesthesia for undergraduate students at University of Milan,
including:
MEDICINA E CHIRURGIA - Polo Centrale (Classe LM-41): D51-39 "Urgenze ed emergenze, medico
chirurgiche" D51-39.14.1 (Polo Centrale) Anestesiologia LEZ + ATT.PROF
ASSISTENZA SANITARIA (Classe L/SNT4): D82-6 " Igiene del lavoro ed emergenze" D82-6.14.1,
Anestesiologia LEZ.
In charge of a number of teaching modules at the Master Course of Intensive Care, University of
Milan, including Coordination of the three day course on "Sepsis and septic shock".
Coordinator of a number of workshops/courses in Anaesthesia and Intensive Care, some of which
involving macro and micro simulation.
Member of the didactic commission at the University of Milan, Faculty of Medicine (Polo centrale).
Member of the didactic commission of the Italian Society of Anesthesia and Intensive Care
(SIIARTI) and leader of one of the Refresher courses of Anesthesia (2008).
Certified instructor of the "Fundamental of Critical Care Course" of the Society of Critical Care
Medicine
INSTITUTIONALS ACTIVITIES
Leader of a clinical project conducted in collaboration with Regione Lombardia - Coordinamento
Trapianti, Centro Nazionale Trapianti and several ICUs, aim of which is to promote the scientific
knowledge on multi-organ donor care by means of multicenter trials, and to implement clinical
protocols of organ donation.
Leader of the sub-committe on Organ donation, Società Italiana di Anestesia Analgesia,
Rianimazione e Terapia Intensiva (SIAARTI), aim of which is to foster organ donation by
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Valenza Franco, MD
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implementing clinical protocols on organ donation, teaching multi-organ donor care to residents in
anesthesia and intensive care, and conducting nationwide surveys on lung procurement.
Member of the study group on Transplantation of thoracic organs, joint committee Società Italiana
Trapianti d'Organo (SITO) and Società Italiana di Anestesia Analgesia, Rianimazione e Terapia
Intensiva (SIAARTI)
Member of the study group on Donation after Cardio-circulatory Dearth - DCD, joint committee
Società Italiana Trapianti d'Organo (SITO) and Società Italiana di Anestesia Analgesia, Rianimazione
e Terapia Intensiva (SIAARTI)
Member of the College of Experts in the review of fellowship applications, European Respiratory
Society (ERS) Science council
Member of the Scientific Board of the Fondazione IRCCS Ca' Granda - Ospedale Maggiore
Policlinico (Prof. Mannucci)
Member of the Ethical Committe Board of the area B of Milano, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
CLINICAL ACTIVITY
From March 1997 staff physician at the Fondazione IRCCS Cà Granda -Ospedale Maggiore
Policlinico, Department of Anaesthesia and Intensive Care (Prof. L. Gattinoni).
Current clinical activity:
Anesthesia for solid organ transplantation (lung, liver, kidney)
Lung reconditioning before transplantation (EVLP)
Anesthesia for thoracic procedures
Anesthesia for obese patients
Intensive Care in the post-surgical settings
OTHER INFROMATIONS
RESEARCH GRANTS
Funding Agency: Regione Lombardia (Ricerca Innovativa)
Title: Ricondizionamento extracorporeo dei polmoni prima del trapianto: crocevia di nuove
prospettive nel processo donatore-trapianto.
Duration: 24 months
Key words: Multiorgan-donor, EVLP, Lung Transplantation
Role: Principal Investigator
Funding Agency: Lega Lombarda Fibrosi Cistica
Title: Uso della circolazione extracorporea per valutare e ottimizzare la funzione degli organi prima
del trapianto: possibile strategia per aumentare il numero di trapianti presso la Fondazione IRCCS
Ca’Granda.
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Valenza Franco, MD
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Duration: 12 months
Key words: EVLP, Lung Transplantation
Role: Principal Investigator
Funding Agency: Centro Nazionale Trapianti (CNT)
Title: " Modulazione del pH durante ventilazione e perfusione del polmone isolato per ridurre
l'incidenza di primary graft dysfunction post-ischemico"
Duration: 12 months
Key words: Lung Transplantation, Ischemia-reperfusion injury
Role: Principal Investigator
Funding Agency: Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico.
Title: Modulazione del pH alla riperfusione post-ischemica: possibile strategia per aumentare il
numero di organi disponibili per il trapianto polmonare.
Duration: 12 months
Role: Principal Investigator
Key words: Lung Transplantation, Ischemia-reperfusion injury
AWARDS
September 2014, Best selected oral presentation. XXXVIII congresso nazionale della Società
Italiana Trapianti d'Organo (SITO), Siena 24-26 Settembre. Title: "The application of an open lung
strategy after cardio-circulatory collapse in rats preserve lung viability and promote the upregulation of protective genes"
October 2013, Best selected oral presentation. XXXVII congresso nazionale della Società Italiana
Trapianti d'Organo (SITO), Bari, 24-26 ottobre. Title: "EVLP: dati preliminari a un anno di followup".
November 2013, Best selected poster award. Nord Italian Transplant program (NITp) Riunione
Tecnico Scientifica 11/12 novembre 2013 Auditorium Palazzo della Regione, Udine. Title: "Ex vivo
lung perfusion to improve donor lung function and increase the number of organs available for
transplantation".
November 2009, Winner of the Eli Lilly – University of Toronto Critical Care Medicine Fellowship
Award. Title: “Effects of extracellular pH modulation during hypoxia on re-oxygenation injury in
human bronchial epithelial cells”.
November 2009, Winner of the Research Project Award from the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. Title: “Modulation of pH at reperfusion as a strategy to increase
the number of lung available for lung transplantation”.
March 2003, “Poster award”, 24rt International Symposium of Intensive Care and Emergency
Medicine (ISICEM, Bruxelles, March 18-21), Symposium chairman: JL Vincent (Belgio), President of
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Valenza Franco, MD
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the jury: J Takala (Findlandia) Title: A more homogeneous distribution of strain within lung
parenchyma attenuates ventilator-induced lung injury in the prone position.
March 2003, “Poster award” 23rd International Symposium of Intensive Care and Emergency
Medicine (ISICEM, Bruxelles, March 18-21), Symposium chairman: JL Vincent (Belgio), President of
the jury: J Takala (Findlandia). Title: Effects of continuous negative extra-abdominal pressure on
intrathoracic blood shift with and without increased intra-abdominal pressure. Experimental
study.
November 1995, Best oral contribution (Selected Papers). Presidents of the jury:.K.Reinhart,
J.Takala and J.L. Vincent. 10th International Postgraduate Course in Critical Care Medicine
(Trieste, 13-19 Novembre 1995). Title: Inhaled Nitric Oxide responsiveness.
November 1995, Best oral contribution (Selected Papers). Presidents of the jury: B.Kremzar, M.R.
Pinsky and J.Takala. 10th Internaional Postgraduate Course in Critical Care Medicine (Trieste, 1319 Novembre 1995).
INVITED GRANT REVIEWER for:
European Society of Intensive Care Medicine (ESICM);
20th TV3 Marató Call on Regeneration and Transplantation of Organ and Tissues.
(http://www.tv3.cat/marato/en/) managed by the Catalan Agency for Information, Assessment
and Quality, CAHIAQ (formerly CAHTA);
National Science Centre, in Polish Narodowe Centrum Nauki (abbr. NCN), executive government
agency set up to fund basic research in the Republic of Poland (http://www.ncn.gov.pl)
VQR 2004-2010, Italy (https://referee.cineca.it)
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
INVITED LECTURES
including those from 2009 to 2014
Scientific meetings of international relevance
The optimal ECLS strategy for PGD after lung transplantation. European Cardio Thoracic Transplant
Meeting 1st ECTTA a section of European Society of Organ Transplantation (ESOT). Budapest,
Hungary. October 3 - 4, 2014
Ex-Vivo lung perfusion for lung transplant: patient safety and economic considerations. European
Association of Cardiothoracic Anaesthesiologists (EACTA) and of the Society of Cardiovascular
Anesthesiologists (SCA), 14th International Congress on Cardiovascular Anesthesia (ICCVA 2014).
Florence, Italy, September 17-19 2014
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Valenza Franco, MD
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The potential multi-organ donor. 25° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 28-30, 2014.
Low TV is not essential during OLV. 25° SMART Congress, Simposio Mostra Anestesia Rianimazione
e Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 28-30, 2014.
Lung optimization in organ donation. The 26th Annual Congress of the European Society of
Intensive Care Medicine, LIVES 2013, 26th Annual Congress, Paris, France, October 05-09, 2013
Controlled mechanical ventilation: the basics. The 26th Annual Congress of the European Society
of Intensive Care Medicine, LIVES 2013, 26th Annual Congress, Paris, France, October 05-09, 2013
Donor preconditioning. International course "The donor surgeon", Padua November 13-15, 2013, V
edition.
Lung reconditioning before transplantation. II International Conference on End Stage Lung
Diseases: Focus on Idiopathic Pulmonary Fibrosis. Padua - Italy, February 22nd, 2013. Palazzo del
Bo’ - Aula Nievo
How to Improve Lung Donation in the Brain Dead Donor. MedTass 2013. 3^ Mediterranean
Transplantation Anesthesiology and Symulation Symposium. IsMETT - Palermo. April 12-13, 2013
The Impact of ICU Treatment on Organ Donation. XVI Annual Meetin of the Critical Care Tuscany
Group. Poggio Imperiale. May, 29-31, 2013
Hypoxia during thoracic surgery. 24° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 8-10, 2013.
The impact of ICU treatment on transplanted organs. The 25th Annual Congress of the European
Society of Intensive Care Medicine (ESICM) Lisbon, Portugal. October 13-17, 2012
Physiology of mechanical ventilation. The 25th Annual Congress of the European Society of
Intensive Care Medicine (ESICM) Lisbon, Portugal. October 13-17, 2012
ECMO and lung transplant program. New perspectives in ECMO 2012 - III International Meeting,
Sesto San Giovanni Milano, Italy. October 5, 2012
A standardized model of brain death, donor transplantation for studes on organ preservation and
reconditioning. European Organ Donation Congress, 24th ETCO-EDC Dubrovnik, Croatia. October
5-7, 2012
Lung procurement for transplant: donor treatment and EVLP techniques. 23° SMART Congress,
Simposio Mostra Anestesia Rianimazione e Terapia Intensiva, MiCo - Milano Congressi, Milano,
Italy. May 9-11, 2012
Anesthesia in the obese patient. 23° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 9-11, 2012
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Valenza Franco, MD
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SvO2 as a guide parameter. 22° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 25-27, 2011
Starches and scientific frauds: where are we? 22° SMART Congress, Simposio Mostra Anestesia
Rianimazione e Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy May 25-27, 2011
Would you correct acidemia in septic shock? 22° SMART Congress, Simposio Mostra Anestesia
Rianimazione e Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy May 25-27, 2011
Ventilator induced lung injury. ESICM Summer Conference, Turin, Italy. Jun 23-25, 2011
The use of Plasma Volume 22° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milan. May 5-7, 2010
SvO2 as a guide parameter. 22° SMART Congress, Simposio Mostra Anestesia Rianimazione e
Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 5-7, 2010
General anesthesia in the obese patient. 21° SMART Congress, Simposio Mostra Anestesia
Rianimazione e Terapia Intensiva, MiCo - Milano Congressi, Milano, Italy. May 9-11, 2009
Polytrauma: optimal blood pH. 29th International Symposium on Intensive Care and Emergency
medicine (ISICEM) Exhibition & Convention Center, Brussels, Belgium. March 13-27, 2009
Critical care in specific patient groups: The morbidly obese. 29th International Symposium on
Intensive Care and Emergency medicine (ISICEM) Exhibition & Convention Center, Brussels,
Belgium. March 13-27, 2009
Lactic acidosis revisited: Should we give bicarbonate? 29th International Symposium on Intensive
Care and Emergency medicine (ISICEM) Exhibition & Convention Center, Brussels, Belgium. March
13-27, 2009
Scientific meetings of national - regional relevance
Il donatore multiorgano. Corso Teorico-Pratico A.A.R.O.I.- EMAC .Novità in Rianimazione :
esperienze a confronto. Roma, 13 dicembre 2014
Il donatore d'organo: dalla cura del malato alla cura degli organi. 68° Congresso Nazionale della
Società Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva. Venezia 22-25 Ottobre
2014
Il precondizionamento degli organi. La Clinica e l'industria nel trapianto di organi solidi. Bologna.
Complesso Belmeloro. 18-19 Settembre 2014.
Il ricondizionamento del polmone nel trapianto: una nuova opportunità. Pneumologia 2014.
Milano, 5-7 giugno 2014 ∙ Centro Congressi Palazzo delle Stelline
pag. 11 of 15
Valenza Franco, MD
_____________________________
Nuove prospettive per il trapianto di polmone. Corso Gestione del Processo di Donazione di Organi
e Tessuti a Scopo di Trapianto. 28, 29 e 30 gennaio 2014. Codice edizione: SDS 13078/AE ,Milano
La gestione del blocco neuromuscolare in chirurgia bariatrica. La gestione del blocco
neuromuscolare. Progetto educazionale regione Lombardia, Milano 7 maggio 2014
Thromboembolic risk in critically ill septic patients. Giornata mediterranea di Infettivologia. Catania, 8 maggio 2014
Trapianto polmonare e organi marginali. 14 Congresso Regionale AAROI-EMAC Sardegna, SIARED,
AIMOS. 8-9 Novembre 2013 Hotel Sa Muvara Aritzo (NU)
La curva PV: cosa ci insegna. Corso L'ABC della ventilazione artificiale. ScuolaMedica Ospedaliera.
B.Go S.Spirito, 12 Dicembre 2013
Strategie di trattamento del donatore e di ricondizionamento polmonare. Eupolis Lombardia, Scuola
di direzione in Sanità. Via Pola 12/14 - 20124 Milano, 5 giugno 2012
Ex vivo lung perfusion: what’s it all about? 4° Congresso della Società Italiana per la Sicurezza e la
Qualità nei trapianti (SISQT)/4 Congress of the Italian Society for Safety and Quality in
Transplantation, Milano, Italy. May 9-11, 2012
Nuove prospettive nel processo donazione trapianto. Riunione Tecnico Scientifica NITp (Nord
Italian Transplant). Ancona 10-11 ottobre 2011
Ex-vivo lung perfusion: possibile strategia per aumentare il numero di polmoni disponibili per il
trapianto. XXXIV congresso nazionale SITO, Società Italiana Trapianti d'Organo, Ancona 7-9
novembre 2010
Elettroliti e plasma expanders. AAROI, Centro Congressuale Pontificia Università Urbaniana, Via
Urbano VIII, 16 (attiguo Ospedale Bambino Gesù), Via del Gianicolo, 15 - Roma 30 ottobre 2010
Fisiopatologia dello schock. AAROI, Centro Congressuale Pontificia Università Urbaniana Via
Urbano VIII, 16 (attiguo Ospedale Bambino Gesù), Via del Gianicolo, 15 - Roma 27 ottobre 2009
Scientific meetings of local relevance
Lung reconditioning before transplantation. Surgical Intensive Care Grand Rounds. Massachussets
General Hospital, August 22, 2014.
Lung reconditioning before transplantation. Hospital Clínic, Barcelona,Spain, 25-26 November
2013
Lung transplantation and marginal lungs. Corso in “Gestione del potenziale donatore di organi.
Linee guida attuali e proproste di trattamento. ”. Azienda Ospedaliera “Istituti Ospitalieri” di
Cremona, Presidio Ospedaliero di Cremona, 6 maggio 2013
pag. 12 of 15
Valenza Franco, MD
_____________________________
Lung transplantation and marginal donors. Chirurgia Toracica, Policlinico Universitario dell'Azienda
Ospedaliera di Padova, via Giustiniani 2, 23 maggio 2012
Attualità e prospettive per il recupero di organi e tessuti a scopo di trapianto. Ventilazione
protettiva - EVLP. Spedali Civili di Brescia, U.O. Formazione Aziendale, Coordinamento locale per i
prelievi di organi e tessuti a scopo di trapianto, Brescia 22 maggio 2012
Monitoraggio emodinamico volumetrico transpolmonare, stato dell’arte. Monitoraggio
emodinamico nel paziente critico: realtà presente e futura. Istituto Clincio Humanitas, IRCCS.
Centro Congressi Humanitas Via Manzoni 113 - Rozzano (Mi), 4 maggio 2012
Lung transplantation and marginal donors. Ospedale “Alessandro Manzoni” aula Conferenze,
Lecco - Via dell’Eremo 9/11, 23 aprile 2012
Il procurement di polmoni per trapianto: Ex –vivo lung perfusion (E.V.L.P. ) e management del
donatore. Sala Consiliare, Azienda Ospedali Riuniti di Bergamo, 16 aprile 2012
Lung transplantation and marginal donors. Azienda Ospedaliera di Padova, Istituto di Anestesia e
Rianimazione. Padova 11 aprile 2012
Il trapianto polmonare e il ricondizionamento d'organo. Azienda Ospedaliera San Gerardo,
Neuroanestesia e Neurorianimazione Dipartimento di Emergenza Urgenza, Monza 12 aprile 2012
Ex-vivo lung perfusion e donatori multiorgano. Istituto di Anestesia e Rianimazione, Fondazione
IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano 12 marzo 2012
Barotrauma e ventilazione protettiva nel donatore. Auditorium Ospedale Santa Chiara, Azienda
Provinciale per i Servizi Sanitari , Provincia Autonoma di Trento, Trento 27 gennaio 2012
Effetti della componente pre-analitica sul referto emogasanalitico. Azienda U.S.L. n. 12 di
Viareggio, Ospedale Versilia, 29 ottobre 2011
Post-conditioning e trapianto polmonare. Azienda Ospedaliera San Gerardo di Monza, Istituto di
Anestesia e Rianimazione, 26 novembre 2010
Ex-vivo lung perfusion nel ricondizionamento del graft polmonare. Niguarda, 8 novembre 2010
Ex-vivo lung perfusion nel ricondizionamento del graft polmonare. Fondazione IRCCS Policlinico San
Matteo, Pavia 15 ottobre 2010
SCIENTIFIC ORGANZIATIONS' MEMBERSHIP and ACTIVITY
Società Italiana di Analgesia Anestesia Rianimazione e Terapia Intensiva (SIAARTI), Member of the
Transplantation section, leader of the working group on multi organ donor care
European Society of Intensive Care Medicine (ESICM), Member of the Acute Lung Injury section,
leader of the working group on multi organ donor care
pag. 13 of 15
Valenza Franco, MD
_____________________________
International Society of Heart and Lung Transplantation (ISHLT), Member of the basic science and
translational section
European Society od Anaesthesia (ESA)
European Society of Organ Transplantation (ESOT)
Società Italiana di Trapianti d'Organo (SITO)
Society of Critical Care Medicine (SCCM)
INVITED PEER REVIEWER for the following international scientific journals:
BMC Gastroenterology
BMC Surgery
Critical Care Medicine
Critical Care
Experimental Biology and Medicine
Intensive Care Medicine
Minerva Anesthesiologica
Journal of Applied Physiology
Journal of Clinical Anesthesia
Pulmonary Pharmacology and Therapeutics
Saudi Journal of Anesthesia
Transplantation International
World Journal of Gastroenterology
APPOINTMENTS:
from July 2008 to June 2009:
Post Doctoral Fellowship, Department of Anesthesia, St.Michael's Hospital, Dr. Slutsky AS Dr.
Zhang H. University of Toronto, Ontario Canada (CA)
from November 2001:
Assistant Professor, University of Milan, Faculty of Medicine, Department of Pathophysiology and
Transplantation, Milan, Italy
September 2001:
Experimental, research and clinical work observer, Royal Brompton Hospital, Department of
Thoracic and Intensive Care Medicine, Imperial College School of Medicine, London (UK)
from March 1997:
Staff physician, Department of Anaesthesia and Intensive Care, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
1993 - 1997:
pag. 14 of 15
Valenza Franco, MD
_____________________________
Residency in Anesthesia and Intensive Care, Department of Anaesthesia and Intensive Care,
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy, University of Milan,
Faculty of Medicine
from November 1993 to February 1995:
Research Fellowship, Respiratory Medicine Division, Mount Sinai Hospital, Dr. A.S. Slutsky.
University of Toronto, Canada(CA)
1992 - 1993:
Military duty Service, Medical Doctor, Centro Socio Educativo, Monza USSL 64, Italy
1990 - 1991:
Student Internship, Institute of Anaesthesia and Intensive Care (Prof L. Gattinoni), Ospedale S.
Gerardo dei Tintori, Monza, University of Milan, Faculty of Medicine, Milan, Italy
1988 - 1990:
Student Internship, Institute of Human Physiology (Prof. Schieppati), University of Milan, Faculty of
Medicine, Milan, Italy
pag. 15 of 15

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