UNIVERSITÀ DEGLI STUDI DI MILANO BICOCCA DOTTORATO DI RICERCA IN SCIENZA E NANOTECNOLOGIA DEI MATERIALI via Cozzi 53, I-20125 Milano, Italy phone: +39 02 6448 5102 CORIMAV fax: +39 02 6448 5400 Venerdì 30 maggio 2014 Ore 15.00 Sala Lauree - Dipartimento di Scienza dei Materiali Fabio Biscarini Life Science Dept., Università di Modena e Reggio Emilia, Via Campi 183, 41125 Modena, Italy Organic Bioelectronics for Regenerative Medicine Electronic transducers of neuronal cellular activity are important devices in neuroscience and neurology. Organic field-effect transistors (OFETs) offer tailored surface chemistry, mechanical flexibility, and high sensitivity to electrostatic potential changes at device interfaces. These properties make them attractive for interfacing electronics to neural cells and performing extracellular recordings and stimulation of neuronal network activity. Here I want to present an emerging area of interest where the OFET is used as a gauge to supply a variety of electrical, chemical and electrochemical stimuli to neuronal cells, in an effort to stimulate their plasticity else to differentiate neuronal stem cells into neurons. I will overview the progresses of an ongoing EU project, “Implantable Organic Nanoelectronics” (I-ONE-FP7) which is aimed to the use of organic electronics in implantable devices for the treatment of the spinal cord injury (SCI). The project is presently at midterm, and I will highlight the advances to date and discuss the direction of further development towards in-vivo experiments on animal model of the SCI. This work involves collaboration of several partners, that I would like to acknowledge through the principal investigators: S. Pluchino (Univ. of Cambridge), M. Berggren and D. Simon (Univ. Linkoeping), F. Zerbetto and S. Rapino (Univ. of Bologna), P. Greco (Scriba Nanotecnologie Srl Bologna), L. Occhipinti (ST Microelectronics Catania), D. Vuillaume (CNRS, Lille), R. Garcia (CSIC Madrid), H. Gomes (Univ. do Algarve), R. Frycek (Amires Sarl, Neuchatel), E. Cerna and V. Velebny (Contipro Dolni Dobrouc), T. Cramer, F. Valle (CNR-ISMN Bologna), S. Casalini, G. Foschi, C. A. Bortolotti, (UNIMORE). This work is supported by EU NMP Project I-ONE Grant Agreement n. 280772. Seminari organizzati nell’ambito del Corso “Seminari”, Dottorato di Ricerca in Scienza e Nanotecnologia dei Materiali. Gli studenti del Dottorato e tutti gli interessati sono cordialmente invitati a partecipare. Il Coordinatore del dottorato Prof. Gianpaolo Brivio Con il contributo di
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