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UNIVERSITÀ DEGLI STUDI DI MILANO BICOCCA
DOTTORATO DI RICERCA
IN SCIENZA E NANOTECNOLOGIA
DEI MATERIALI
via Cozzi 53, I-20125 Milano, Italy
phone: +39 02 6448 5102
CORIMAV
fax: +39 02 6448 5400
Venerdì 30 maggio 2014 Ore 15.00
Sala Lauree - Dipartimento di Scienza dei Materiali
Fabio Biscarini
Life Science Dept., Università di Modena e Reggio Emilia, Via Campi 183, 41125 Modena, Italy
Organic Bioelectronics for Regenerative Medicine
Electronic transducers of neuronal cellular activity are important devices in neuroscience and neurology.
Organic field-effect transistors (OFETs) offer tailored surface chemistry, mechanical flexibility, and high
sensitivity to electrostatic potential changes at device interfaces. These properties make them attractive for
interfacing electronics to neural cells and performing extracellular recordings and stimulation of neuronal
network activity.
Here I want to present an emerging area of interest where the OFET is used as a gauge to supply a variety of
electrical, chemical and electrochemical stimuli to neuronal cells, in an effort to stimulate their plasticity else
to differentiate neuronal stem cells into neurons. I will overview the progresses of an ongoing EU project,
“Implantable Organic Nanoelectronics” (I-ONE-FP7) which is aimed to the use of organic electronics in
implantable devices for the treatment of the spinal cord injury (SCI). The project is presently at midterm, and I
will highlight the advances to date and discuss the direction of further development towards in-vivo
experiments on animal model of the SCI.
This work involves collaboration of several partners, that I would like to acknowledge through the principal
investigators: S. Pluchino (Univ. of Cambridge), M. Berggren and D. Simon (Univ. Linkoeping), F. Zerbetto and
S. Rapino (Univ. of Bologna), P. Greco (Scriba Nanotecnologie Srl Bologna), L. Occhipinti (ST Microelectronics
Catania), D. Vuillaume (CNRS, Lille), R. Garcia (CSIC Madrid), H. Gomes (Univ. do Algarve), R. Frycek (Amires
Sarl, Neuchatel), E. Cerna and V. Velebny (Contipro Dolni Dobrouc), T. Cramer, F. Valle (CNR-ISMN Bologna), S.
Casalini, G. Foschi, C. A. Bortolotti, (UNIMORE).
This work is supported by EU NMP Project I-ONE Grant Agreement n. 280772.
Seminari organizzati nell’ambito del Corso “Seminari”, Dottorato di Ricerca in Scienza e
Nanotecnologia dei Materiali.
Gli studenti del Dottorato e tutti gli interessati sono cordialmente invitati a partecipare.
Il Coordinatore del dottorato
Prof. Gianpaolo Brivio
Con il contributo di