Cover Page The handle http://hdl.handle.net/1887/29721 holds various files of this Leiden University dissertation. Author: Steenhoven, Timothy Jason van der Title: On prevention of second hip fracture surgery : epidemiological and biomechanical aspects of elastomer femoroplasty Issue Date: 2014-11-11 On prevention of second hip fracture surgery Epidemiological and biomechanical aspects of elastomer femoroplasty Tim J. van der Steenhoven Cover design: M.W.G.A. Bronkhorst Layout: M. Hutteman © T.J. van der Steenhoven, 2014 ISBN 978-94-6169-580-2 The research described in this thesis was financially supported by Bronovo Research Fonds, Stichting Extra-curriculaire Activiteiten Haagse Chirurgen, Stichting Anna Fonds, Maatschap Haagse Chirurgen, and Mathys Orthopaedics B.V. On prevention of second hip fracture surgery Epidemiological and biomechanical aspects of elastomer femoroplasty PROEFSCHRIFT ter verkrijging van de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker, volgens besluit van het College voor Promoties te verdedigen op dinsdag 11 november 2014 klokke 16.15 uur door Timothy J. van der Steenhoven geboren te Schiedam in 1972 PROMOTIECOMMISSIE Promotores Prof. dr. R.G.H.H. Nelissen Prof. dr. ir. E.R. Valstar Co-promotor Dr. A.C. de Vries Overige leden Prof. dr. I.B. Schipper Prof. dr. A. van Kampen Prof. dr. M.H.J Verhofstad (Universiteit Nijmegen) (Universiteit Rotterdam) To my family CONTENTS Chapter 1 General introduction and outline of the thesis Part 1 Sequelae of second hip fracture surgery Chapter 2 A retrospective analysis of bilateral fractures during a 16-year period: localization and variation in treatment of second hip fractures 19 Chapter 3 Complications and institutionalization are almost doubled after second hip fracture surgery in the elderly patient 33 Part 2 Elastomer Femoroplasty Chapter 4 The concept of preventive elastomer femoroplasty in individuals with high risk of hip fracture 49 Chapter 5 Augmentation with silicone stabilizes proximal femur fractures: an in vitro biomechanical study 57 Chapter 6 Elastomer femoroplasty prevents hip fracture displacement. An in vitro biomechanical study comparing two minimal invasive femoroplasty techniques 71 Chapter 7 Cyclic loading of fractured cadaveric femurs after elastomer femoroplasty: An in vitro biomechanical study 87 Chapter 8 Feasibility of osteosynthesis of fractured cadaveric hips following preventive elastomer femoroplasty 101 Chapter 9 Thrombogenicity of a new injectable biocompatible elastomer for aneurysm exclusion, compared to expanded polytetrafluoroethylene in a human ex vivo model 115 Chapter 10 General Discussion 131 Chapter 11 Summary 141 Chapter 12 Nederlandse Samenvatting 147 Appendices Curriculum Vitae 9 155 List of publications 156 Acknowledgements 159
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