Detailed program of oral communications and poster sessions Longdagen 23-24 April, 2014 Oral Communications – Basic Science O1 Thursday April 24, 13:00-14:30 Chairs: Irene Heijink, Groningen Mirjam Kool, Rotterdam O1.1 Insufficient read-through correction of premature termination codons by PTC124 and G418 in human cystic fibrosis organoids. D.D. van Ommen, L.A.W. Vijftigschild, H.M. Janssens, K.M. de Winter-de Groot, C.K. van der Ent, J.M. Beekman. Utrecht, Rotterdam, The Netherlands O1.2 Hyperactivity of the IL33-ST2 axis during postnatal alveolarization increases susceptibility to house dust mite sensitization via skewing of CD11b+ dendritic cells. I.M. de Kleer, M. Willart, M. Plantinga, M. Kool, H. Hammad, R. Hendriks, B. Lambrecht. Ghent, Belgium, Rotterdam, Utrecht, The Netherlands O1.3 A lysate of Helicobacter pylori induces IL-10 secretion by human monocyte-derived dendritic cells and primes for IL-10 producing T cells. Yolanda van Wijck, Alwin J. van der Ham, Leonie Hussaarts, Maria Yazdanbakhs2, Pieter S. Hiemstra, Anne Müller, Hermelijn H. Smits, Christian Taube.. Leiden, The Netherlands, Zürich, Switzerland O1.4 The RANK/RANKL/OPG-axis in pulmonary fibrosis: which cell types are involved? CE Boorsma, C Draijer, RH Cool, CA Brandsma, G Nossent, D Brass, W Timens, BN Melgert. Groningen, The Netherlands, Durham, NC, USA O1.5 Muscarinic M3 receptors on structural cells regulate neutrophilic inflammation in mice LEM Kistemaker, R van Os, A Ausema, IST Bos, MN Hylkema, PS Hiemstra, J Wess, H Meurs, HAM Kerstjens, R Gosens. Groningen, Leiden, The Netherlands, Bethesda, USA O1.6 Acetate is more effective than a glucocorticoid steroid at preventing and reducing neutrophilic airway inflammation in a cigarette smoke induced mouse model for COPD Gillina F.G. Bezemer, Ingrid van Ark, Amy Marijne, A. Thea Leusink-Muis, Aletta D. Kraneveld, Johan Garssen, Gert Folkerts. Utrecht, The Netherlands Oral Communications – Clinical Science O2 Thursday April 24, 13:00-14:30 Chairs: Kors van de Ent, Utrecht Thys van der Molen, Groningen 1 O2.1 Accelerated ageing in the ICE-Age study: Individualized COPD evaluation in relation to Ageing. Poornima Gopal, Niki L. Reynaert, Frits M.E. Franssen, Geja Hageman, Emiel F.M. Wouters, Erica P.A. Rutten. Maastricht, Horn, the Netherlands O2.2 Exacerbation of moderate asthma during inhaled steroid withdrawal does not induce systemic activation of coagulation M.M.S. Sneeboer, M.A. van de Pol, N. Fens1, C.J. Majoor, J.C. Meijers, P.W. Kamphuisen, R. Lutter, P.J. Sterk, E.H.D. Bel. Amsterdam, Groningen, The Netherlands O2.3 SOLUBLE CD59 IS A NOVEL BIOMARKER FOR THE PREDICTION OF THE BRONCHIOLITIS OBLITERANS SYNDROME K. Budding, E.A. van de Graaf, T. Hoefnagel, C.E. Hack, H.G. Otten. Utrecht, The Netherlands O2.4 Differential macrophage subsets in males and females with asthma Christina Draijer, Patricia Robbe, Carian E. Boorsma, Machteld N. Hylkema, Wim Timens, Dirkje S. Postma, Nick H.T. ten Hacken, Barbro N. Melgert. Groningen, The Netherlands O2.5 Increased Bruton tyrosine kinase (BTK) -protein expression in B cells in patients with pulmonary arterial hypertension. P. Heukels, L.P. Kil, J.A.C. van Hulst, M.J. W. de Bruijn, M. van Nimwegen, L.M. van den Toorn, K.A.T. Boomars, J.W. Roos-Hesselink, H.C. Hoogsteden, R.W. Hendriks, B. van den Blink, M. Kool. Rotterdam, The Netherlands O2.6 Tumor microenvironmental studies indicate controlled trafficking and preferential homing of immune cells towards the tumor L.A. Lievense, R. Cornelissen, K. Bezemer, M.E.H. Kaijen, R.W. Hendriks, J.G.J.V. Aerts, J.P.J.J. Hegmans Rotterdam, The Netherlands Poster presentations Wednesday April 23, 15:00-16:00 Poster Session P1: Basic Science Chairs: Leo Koenderman, Utrecht Barbro Melgert, Groningen P1.1 The isolation of culturable micro-organisms from tobacco, cigarette smoke and second hand cigarette smoke: implications for COPD Gillina F.G. Bezemer, Éric Jubinville, Aniek Dijkshoorn, Frank Stassen, Petra Wolffs, Nathalie Turgeon, Marc Veillette, Catherine Viel, Marie-Eve Dubois, Steve Labrie, Johan Garssen, Caroline Duchaine, Gert Folkerts. Utrecht, Maastricht, The Netherlands, Ste-Foy Québec, Canada; P1.2 Crosstalk between epithelium and fibroblasts; implications for COPD Emmanuel T. Osei, Corry-Anke Brandsma, Jacobien A. Noordhoek, Wim Timens, Dirkje Postma, Irene Heijink. Groningen, The Netherlands P1.3 TELOMERE LENGTH OF PERIPHERAL BLOOD MONOCYTES IN INTERSTITIAL LUNG DISEASES R. Snetselaar, C.H.M. van Moorsel, K.M. Kazemier, J.J. van der Vis, J.C. Grutters. Nieuwegein, Utrecht, the Netherlands P1.4 Polymorphisms of SLCO1B1 transporter and CYP enzymes are not associated with development of idiopathic interstitial pneumonia in statin users HA Crommelin, VHM Deneer, E Schelhaas, CHM van Moorsel, JC Grutters.. Nieuwegein, The Netherlands; P1.5 Mesenchymal stromal cells reduce acute LPS-induced pulmonary and systemic inflammation P.Padmini.S.J.Khedoe, Sander Kooijman, Merete Long, Melissa van Pel, Patrick C.N. Rensen, Jimmy F.P. Berbée, Pieter S. Hiemstra. Eindhoven, Leiden, The Netherlands 2 P1.6 Leptin-induced Neutrophil Migration In Acute Lung Injury: An Important Role For Alternate Signaling Pathways N.D. Ubags, E. Burg, C. M. Hayes, M.E. Poynter, E.F. Wouters, J.H. Vernooy, B.T. Suratt. Maastricht, The Netherlands; Vermont, Burlington, VT, USA P1.7 Internalization of silica in bronchial epithelial cells K.J.C. Sanders, P.M.P. Peeters, N.L. Reynaert. Maastricht, The Netherlands P1.8 Epigenetic Analysis of Airway Epithelium: Prenatal Programming by Maternal Smoking? KF Meyer, J Cao, MV Zwier, J Song, M Reinders-Luinge, W Kooistra, W Timens, P Nguyen, K Haley, T Plösch, L Kobzik, MN Hylkema. Groningen, The Netherlands, Boston, USA P1.9 Azithromycin differentially regulates IL-13 induced periostin, CLCA1 and SERPINB2 expression in human bronchial epithelial cells T.C.J. Mertens, R.M. Verhoosel, P.S. Hiemstra, C. Taube. Leiden, The Netherlands P1.10 Effects of TGF-β on microRNA expression in COPD and control lung fibroblasts V. Rajendran, J.L. Kluiver, A. van den Berg, A. Spira, M. Lenburg, J. Campbell, D.S. Postma, W. Timens, C.A. Brandsma. Groningen, The Netherlands, Boston, USA P1.11 ADAM17 activity is increased by Cigarette Smoke treatment and CFTR deficiency in lung epithelial cells Marta Stolarczyk, Gimano D. Amatngalim, Guido Veit, Gergely L. Lukacs, Pieter S. Hiemstra, Bob J Scholte. Rotterdam, Netherlands, Leiden, Netherlands; Montreal, Canada P1.12 Chronic cigarette smoke (CS) exposure alters differentiation of primary bronchial epithelial cells, cultured at the air-liquid interface (PBEC-ALI) JA Schrumpf, JB Veldkamp, TCJ Mertens, EFA van 't Wout, MC Zarcone, GD Amatngalim, PS Hiemstra. Leiden P1.13 Glucocorticoid Receptor-dependent impairment of protein synthesis regulation in hypoxia induced muscle atrophy C.C. de Theije, A.M.W.J. Schols, W.H. Lamers, E.S. Kohler, R.C.J. Langen. Maastricht P1.14 Hypoxia differentially regulates muscle oxidative fiber-type and metabolism in a HIF-1αdependent manner Ilse G.M. Slot, Annemie M.W.J. Schols, Bettine A.H. Vosse, Marco C.J.M. Kelders, Harry R. Gosker. Maastricht P1.15 TNF-α-induced classical NF-κB activation stimulates skeletal muscle glycolytic metabolism through a HIF-1α-dependent mechanism Remels AHV, Gosker HR, Langen RCJ, Schols AMWJ. Maastricht P1.16 Latrophilin 3 a new receptor which increased airway smooth muscle mass and contraction in asthmatic airways A. Faiz, C. Donovan, B.G. Oliver, A.J. Halayko, K. Detillieux, J.P.T. Ward, T. Lee, J.L. Black, J.E. Bourke, B. McParland, J.K. Burgess Glebe, NSW/AU, Sydney, NSW/AU, Melbourne, VIC/AU, Winnipeg, MB/CA, London/UK Poster Session P2: Clinical Science Chairs: Bernt van den Blink, Rotterdam Anne-Marie Dingemans, Maastricht P2.1 Prevalence, two-year stability and predictive performance of multiple-trigger and episodic viral wheeze in preschool children Gerben ter Riet, Karina E. van Wonderen, Lonneke B. van der Mark, Ronald B. Geskus, Wim M.C. van Aalderen, Patrick J.E. Bindels. Amsterdam, Rotterdam 3 P2.2 Decreased lung function precedes severe RSV infection and post-RSV wheeze in term infants Kim Zomer-Kooijker, Cuno S.P.M. Uiterwaal, Anne C. van der Gugten, Berry Wilbrink, Louis J Bont, Cornelis K. van der Ent. Utrecht, Bilthoven P2.3 The identification of asthma phenotypes by categorical PCA: combinatorial analysis of clinical parameters and dysfunctional blood eosinophils Bart Hilvering, Susanne Vijverberg, L. Houben, Rene Schweizer, Jan-Willem Lammers, Leo Koenderman. Utrecht, the Netherlands P2.4 Biomarkers for sputum eosinophilia in mild-moderate and severe adult-onset asthma patients G.A. Westerhof, D.A. Korevaar, M. Amelink, S.B. de Nijs, J.C. de Groot, E.J. Weersink, A. ten Brinke, P.M.M. Bossuyt, E.H.D. Bel. Amsterdam, Leeuwarden P2.5 Clinical and histological comparison of smoking and non-smoking patients with severe asthma in the U-BIOPRED cohort P.P.W. Hekking, A.H. Wagener, E.H. Bel, P.J. Sterk, U-BIOPRED Study group. Amsterdam; U-BIOPRED study group listed at http://www.europeanlung.org/en/assets/microsites/ubiopred/files/ubiopred_study_groups.pdf P2.6 Association of COPD and smoking status with bone density and vertebral fractures in male lung cancer screening participants Firdaus A Mohamed Hoesein, Werner U de Jong, Pim A de Jong, Rozemarijn Vliegenthart, Ivana Isgum, Matthijs Oudkerk, Carlijn van der Aalst, Harry J de Koning, Jan-Willem J Lammers. Utrecht, Groningen, Rotterdam, The Netherlands P2.7 Sarcopenia in relation to physical functioning in COPD Coby van de Bool, Erica Rutten, Emiel Wouters, Annemie Schols. Maastricht, Horn, the Netherlands. P2.8 Associations between comorbid load and baseline characteristics in COPD patients with comorbidities: preliminary results Anke Lenferink, Prof. Dr. Job van der Palen, Prof. Peter Frith MD,4, Dr. Paul van der Valk MD, Dr. Tanja Effing. Enschede, the Netherlands; Adelaide, Australia P2.9 MUC5B promoter polymorphism and susceptibility to pulmonary fibrosis in a Dutch cohort J.J. van der Vis, R. Snetselaar, J.C. Grutters, C.H.M. van Moorsel. Nieuwegein, Utrecht, The Netherlands P2.10 Assessment and standardization of chest CT in the European Cystic Fibrosis Society - Clinical Trial Network W. Kuo, E. Salamon, K.M. Logie, E.C. van der Wiel, M.P.C. Kemner-van de Corput, M. van Straten, H.A.W.M. Tiddens. Rotterdam, the Netherlands P2.11 30 Seconds tidal breathing method with AeroEclipse II nebulizer versus Aerosol Provocation System (APS) in methacholine challenge testing. Ellen Ruberg, Irene Steenbruggen, Jan Willem van den Berg. Zwolle P2.12 Single-breath diffusion: comparison between helium and methane as tracer gases in COPD and healthy controls. RO Salvador, E Dijkers, RP van Steenwijk, PJ Sterk. Amsterdam P2.13 Perceived health related quality of life in COPD patients: the role of illness perceptions Saskia Weldam, Jan-Willem Lammers, Monique Heijmans, Marieke Schuurmans. Utrecht P2.14 Integrating the patient perspective in coverage decisions regarding pharmaceuticals - the development of a questionnaire F.A. van Jaarsveld, L. Naber, C.D.Dirksen, P. Bresser, G.J.Teunissen, M.S.Wijsenbeek. Amersfoort, Maastricht, Amsterdam, Rotterdam, the Netherlands P2.15 WHAT ARE THE OPINIONS, EMOTIONS AND NEEDS OF ASTHMA AND COPD PATIENTS TOWARDS A PATIENT WEB PORTAL: RESULTS FROM A FOCUSGROUP STUDY 4 E. I. Metting, T. Schrage, R. A. Riemersma, J. W. Kocks, R. Sanderman, T. van der Molen. Groningen P2.16 LifeLines: a unique data and sample resource for research in pulmonology S. Scholtens, J.M. Vonk, A. Dotinga, H.M. Boezen, D.S. Postma, R.P. Stolk. Groningen, the Netherlands Poster presentations Thursday April 24, 14:30-15:30 Poster Session P3: Basic Science Chairs: Annemie Schols, Maastricht Stan de Kleijn, Leiden P3.1 Chronic exposure to HDM results in persistent neutrophilia and airway remodeling in mice Heleen Vroman, Ingrid M. Bergen, Menno van Nimwegen, Jennifer A.C. van Hulst, Rudi W. Hendriks, Bernt van den Blink, Mirjam Kool. Rotterdam, the Netherlands P3.2 Lymph Node-Derived T Lymphocytes Display A Highly Activated And Proliferative State In Pulmonary Sarcoidosis C.E. Broos, M. van Nimwegen, J.C.C.M. in 't Veen, L.M. van den Toorn, M.S. Wijsenbeek, K.A.T. Boomars, J.T. Annema, H.C. Hoogsteden, R.W. Hendriks, M.Kool, B.van den Blink. Rotterdam; Amsterdam P3.3 Schistosome-induced pulmonary B cells protect against allergic airway inflammation and show a reduced capacity to drive Th2 cytokine responses L.E.P.M. van der Vlugt, Katja Obieglo, Simone Haeberlein, Arifa Ozir-Fazalalikhan, J. Sjef Verbeek, Maria Yazdanbakhsh, Hermelijn H. Smits. Leiden, The Netherlands P3.4 Airway epithelial basal cell expression of the antimicrobial peptide RNase 7: a second line of defense induced upon epithelial injury Gimano D. Amatngalim, Yolanda van Wijck, Yvonne de Mooij-Eijk, Renate M. Verhoosel, Pieter S. Hiemstra Leiden, the Netherlands P3.5 A direct anti-viral role for eosinophils? Suzanne M. Bal, Yanaika S. Sabogal Piñeros, Lara Ravanetti, Annemiek Dijkhuis, Rene Lutter. Amsterdam P3.6 Farm dust exposure alters macrophage phenotype and morphology in vitro: protective role in the hygiene hypothesis? T Borg, P Robbe, C Draijer, W Timens, A Spierenburg, I Wouters, B Melgert, M Hylkema. Groningen, Utrecht, The Netherlands P3.7 The Damage Associated Molecular Pattern (DAMP) release signature relates to susceptibility to develop airway neutrophilia upon cigarette smoke exposure Simon D. Pouwels, Irene H. Heijink, Lisette E. den Boef, Marike H. Boezen, Antoon J.M. van Oosterhout, Martijn C. Nawijn. Groningen, The Netherlands P3.8 Ratio of intratumoral macrophage phenotypes predicts local tumor outgrowth in malignant pleural mesothelioma patients L.A. Lievense, R. Cornelissen, J.L. Robertus, H.C. Hoogsteden, J.P.J.J. Hegmans, J.G.J.V. Aerts. Rotterdam P3.9 Classification of pulmonary neuro-endocrine tumours: too diverse for the clinician! J.L. Derks, E.J. Speel, M. Béndek, A-M.C. Dingemans. Maastricht P3.10 Treatment-induced immunological alterations in peripheral blood of stage IV non-small cell lung cancer patients Pauline de Goeje, Marlies Heuvers, Koen Bezemer, Cynthia Waasdorp, Joost Hegmans and Joachim Aerts. Rotterdam 5 P3.11 Effect of chemotherapy and radiotherapy on function and composition of the immune system in NSCLC Mink Schinkelshoek, Mehrdad Talebian Yazdi, Nikki Loof, Marij Welters, Sjoerd van der Burg. Leiden P3.12 Vitamin D3 is effective as an adjuvant for subcutaneous immunotherapy in a grass pollen-driven mouse model of asthma L. Hesse, M.C. Nawijn, A.H. Petersen, J.N.G. Oude-Elberink, J. Brimnes, A.J.M. van Oosterhout. Groningen, The Netherlands; Hørsholm, Denmark. P3.13 VX-809 and VX-770 treatment in rectal CF organoids expressing class I-V CFTR mutations J.F. Dekkers, E. Kruisselbrink, A.M. Vonk, H.R. de Jonge, H.M. Janssens, I. Bronsveld, K.M. de Winter, C.K. van der Ent, J.M. Beekman. Utrecht, Rotterdam, the Netherlands P3.14 PDE3 inhibition by oral enoximone suppress allergic airway inflammation in a house dust mite asthma model. New asthma treatment opportunity for an old drugs Alex KleinJan, Menno van Nimwegen, Jan Beute, Rudi Hendriks. Rotterdam, Lelystad, Dronten, Emmeloord P3.15 Enoximone in severe asthma Jan Beute, Alex KleinJan. Lelystad, Rotterdam P3.16 Quadriceps muscle fibre type shift is more pronounced in sarcopenic patients with COPD Coby van de Bool, Harry Gosker, Bram van den Borst, Celine op den Kamp, Ilse Slot, Annemie Schols Maastricht, the Netherlands. P3.17 Preserved muscle oxidative metabolic phenotype in clinical cancer cachexia H.R. Gosker, C.M. Op den Kamp, S. Lagarde, D.Y. Tan, F.J. Snepvangers, A.C. Dingemans, R.C. Langen, A.M. Schols. Maastricht, the Netherlands Poster Session P4: Clinical Science Chairs: Yvonne Heijdra, Nijmegen Peter Merkus, Nijmegen P4.1 The relation between hyperinflation and daily activity in COPD patients Steven Dijkhuis, Marjolein Brusse-Keizer, Paul van der Valk, Monique Tabak, Frans de Jongh. Enschede P4.2 Effectiveness of self-treatment of exacerbations in COPD patients: two-year follow-up of the COPE-II study Marlies Zwerink, Huib A.M. Kerstjens, Job van der Palen, Paul van der Valk, Marjolein Brusse-Keizer, Gerhard Zielhuis, Tanja Effing. Enschede, Groningen, Nijmegen, the Netherlands; Daw Park, South Australia, Australia; Adelaide, South Australia, Australia P4.3 A community-based exercise programme in COPD self-management: two-year follow-up of the COPE-II study Marlies Zwerink, Job van der Palen, Huib A.M. Kerstjens, Paul van der Valk, Marjolein Brusse-Keizer, Gerhard Zielhuis, Tanja Effing. Enschede, Groningen, Nijmegen, Daw Park, South Australia, Australia; Adelaide, South Australia, Australia P4.4 Patiëntenparticipatie bij de ontwikkeling van een individueel zorpglan voor mensen met astma de Lange-Tichelaar, T., Pittens, C.A.C.M., Zweekhorst, M., Broerse, J.E.W.. Amsterdam P4.5 How to assess COPD health status in secondary care clinical practice; preliminary results from a Dutch Delphi procedure EFMM van den Akker, JCCM in 't Veen, NH Chavannes, MP Rutten-van Mölken, AJ van ’t Hul. Rotterdam, Nijmegen, Leiden P4.6 The prevalence of adult severe refractory asthma in the Netherlands P.P.W. Hekking, R.R.L. Wener, M.L. Bouvy, M. Amelink, E.H. Bel. Amsterdam 6 P4.7 Unbiased clustering of children with asthma or pre-school wheeze using the U-BIOPRED electronic nose platform. P. Brinkman, S. Hashimoto, prof. W.M. van Aalderen, prof. P.J. Sterk, U-BIOPRED study group. Amsterdam; U-BIOPRED study group listed at http://www.europeanlung.org/en/assets/microsites/ubiopred/files/ubiopred_study_groups.pdf P4.8 Identification of atopy amongst wheezy infants via electronic nose M. P. van der Schee, S. Hashimoto, M. van den Ouweland, N. Adriaens, A. C. Schuurman, A. B. Sprikkelman, E. G. Haarman, W. M. C. van Aalderen, P. J. Sterk, EUROPA study group. Amsterdam P4.9 Determinants of quality of life in children with asthma Kim Zomer-Kooijker, Cuno S.P.M. Uiterwaal, Anke-Hilse Maitland-vd Zee, Walter A.F Balemans, Bart E. van Ewijk, Maartje F. van Velzen, Cornelis K. van der Ent. Utrecht, Nieuwegein, Blaricum, Amersfoort P4.10 The interrupter resistance measured with 2 systems; a comparison between the Whistler lfmi and the MicroRint device. Joyce Tersmette, Rolien Bekkema. Utrecht P4.11 Comparison of new and old DLCO equipment in a pulmonary function laboratory Leidy Lammers, Irene Steenbruggen, Mariët van Doornik, Hans Grotjohan. Zwolle P4.12 Digital tool for support of medical indoor environment counselling F.E. van Boven on behalf of Dutch working group on allergen avoidance, Verpleegkundigen & Verzorgenden Nederland P4.13 Patient specific evaluation of regional antibiotic concentration levels in a cohort of patients with cystic fibrosis A.C.Bos, C. van Holsbeke, J.W. de Backer, M. van Westreenen, W.G. Vos, H.M. Janssens, H.A.W.M. Tiddens Rotterdam, the Netherlands; Kontich, Belgium P4.14 Health Impact Assessment; Wat is een effectieve bestrijding van longziekten door werk? Birgit van Duuren, Ruud Boessen, Anjoeka Pronk. Zeist 7 First or corresponding author index Last Name Akker Amatngalim Bal Bekkema Beute Bezemer Bezemer Bool Bool Boorsma Borg Bos Boven Brinkman Broos Budding Crommelin Dekkers Derks Dijkhuis Draijer Duuren Faiz Goeje Gopal Gosker Hekking Hekking Hesse Heukels Hilvering Jaarsveld Khedoe Kistemaker Kleer KleinJan Kuo Lange-Tichelaar Lenferink Lievense Lievense Mertens Metting Meyer Mohamed Hoesein Ommen Osei Pouwels Rajendran Presentation number P4.5 P3.4 P3.5 P4.10 P3.15 O1.6 P1.1 P2.7 P3.16 O1.4 P3.6 P4.13 P4.12 P4.7 P3.2 O2.3 P1.4 P3.13 P3.9 P4.1 O2.4 P4.14 P1.16 P3.10 O2.1 P3.17 P4.6 P2.5 P3.12 O2.5 P2.3 P2.14 P1.5 O1.5 O1.2 P3.14 P2.10 P4.4 P2.8 O2.6 P3.8 P1.9 P2.15 P1.8 P2.6 O1.1 P1.2 P3.7 P1.10 8 Remels Riet Ruberg Salvador-Ong Sanders Schinkelshoek Scholtens Schrumpf Slot Sneeboer Snetselaar Steenbruggen Stolarczyk Theye van der Schee Vernooy Vis Vlugt Vroman Weldam Westerhof Wijck Zomer-Kooijker Zomer-Kooijker Zwerink Zwerink P1.15 P2.1 P2.11 P2.12 P1.7 P3.11 P2.16 P1.12 P1.14 O2.2 P1.3 P4.11 P1.11 P1.13 P4.8 P1.6 P2.9 P3.3 P3.1 P2.13 P2.4 O1.3 P2.2 P4.9 P4.2 P4.3 9
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