第９回発生ダイナミクス分野主催セミナー日時： 2014年 8月 7日（木） 11：00〜会場：片平・生命科学プロジェクト研究棟 1階講義室A（104号室）講演者： Dr. Hideaki Mizuno Biochemistry, Molecular and Structural Biology Section, Department of Chemistry, KU Leuven, Leuven, Belgium 題目： Functional imaging and superresolution microscopy using fluorescent proteins 本セミナーは生命科学研究科単位認定セミナー（１ポイント）です This seminar will be held in English. セミナーは英語で行います【Summary】 Fluorescent proteins become indispensable tools in the field of life science to label intracellular molecules non-invasively. Various colors of fluorescent proteins are now available, which makes multicolor imaging possible. By applying the color variants to Förester resonance energy transfer (FRET), we could design genetically encoded functional probes. The genetically encoded probes are applicable for imaging in intact animal since it can be introduced by genetic engineering method. In addition to the color variation, we have found unique fluorescent proteins that show photoswitching property. These proteins serve as a fluorophore to track molecules and highlight cells on a microscope. Recently, based on the photoswitchable fluorescent protein, a new microscopic modality circumventing the diffraction limit of light was invented. Here I introduce our recent achievement of functional imaging in intact animal and biological applications of superresolution imaging. 連絡先：生命科学研究科発生ダイナミクス分野杉本亜砂子 E-mail: [email protected] TEL: 022-217-6194