V-Go Start Guide

Starting and titrating V-Go
Insulin Delivery Device
®
V-Go Actual Size
A prescriber’s guide
to dosing
Start
Choose the appropriate V-Go® option
based on the patient's body weight.
• V-Go delivers a continuous subcutaneous insulin infusion (CSII)
• CSII typically reduces total daily insulin dose by 25% to 30%1
Adults on basal insulin only (± OADs)2,3
Patient’s
body weight
≤220 lb
>220 lb
x 0.45 kg/lb x 0.5 U/kg
Basal rate
V-Go 20
Units/24 hours
Basal rate
V-Go 30
Units/24 hours
Bolus dosing
2 clicks/meal
Bolus dosing
3 clicks/meal
1 click = 2 Units
1 click = 2 Units
Adults on MDI or premixed insulin1
Patient’s
body weight (kg)
x 0.5
50%
basal rate
Basal rate
V-Go 20, 30, or 40
Units/24 hours
OAD = oral antidiabetic drug
50%
bolus dosing
+
Divide bolus doses
between meals
Maximum V-Go bolus capacity:
36 Units/day in 2-Unit increments
Titrate
Optimize V-Go bolus dosing
before adjusting the basal rate.
1. Titrate mealtime clicks each week until patient
reaches preprandial goal
2. If fasting glucose is still not optimized, consider switching
to the next V-Go option3
Premeal blood glucose
consistently not at goal*
Preprandial glucose 70-130 mg/dL†4
1.
Add 1 click to previous meal‡
1 click = 2 Units
Titrate bolus dosing weekly until optimized
Premeal goal
achieved
If fasting
blood
glucose
is also
at goal,
continue
to assess
weekly
Premeal goal
not achieved
All clicks used
2.
If fasting
blood
glucose is
not at goal
Consider
increasing
basal rate to
next V-Go option
Decrease bolus dose
by 1 to 2 clicks
per meal
Fasting glucose >180 mg/dL†5
*If the median of the weekly premeal readings is
above target, continue to titrate the bolus dose.
Customize for each patient.
†
For example, if a predinner reading is consistently high,
adjust the bolus dose at lunch.
‡
Get patients started with 2 prescriptions
V-Go® Rx
Select the appropriate
V-Go option
Insulin Rx
U-100 fast-acting insulin*
• 2 vials for V-Go 20
• 3 vials for V-Go 30
and V-Go 40
Meet patient needs with 3 V-Go options
†
†
†
Patients can push the Bolus Delivery Button only 18 times in every 24-hour period.
Each push of the Bolus Delivery Button delivers 2 Units of insulin (1 click = 2 Units).
†
Call Valeritas Customer Care live 24/7 at 1-866-881-1209 or visit www.go-vgo.com.
Important Risk Information:
If regular adjustments or modifications to the basal rate of insulin are required in a 24-hour
period, or if the amount of insulin used at meals requires adjustments of less than 2-Unit
increments, use of the V-Go Disposable Insulin Delivery Device may result in hypoglycemia.
The following conditions may occur during insulin therapy with the V-Go: hypoglycemia (low
blood glucose) or hyperglycemia (high blood glucose). Other adverse reactions associated
with V-Go use include skin irritation from the adhesive pad or infections at the infusion site.
The V-Go should be removed before any magnetic resonance imaging (MRI) testing.
*A U-100 fast-acting insulin should be used with V-Go. Humalog® (insulin lispro, rDNA origin) and NovoLog®
(insulin aspart, rDNA origin) have been tested by Valeritas, Inc. and found to be safe for use in V-Go.
References: 1. Bode BW, et al. Diabetes Metab Res Rev. 2002;18(suppl 1):S14-S20. 2. Edelman SV, et al. Diabetes Technol Ther.
2010;12(8):627-633. 3. Data on file. Valeritas, Inc. 4. American Diabetes Association. Diabetes Care. 2013;36(suppl 1):S11-S66.
5. Nathan DM, et al. Diabetes Care. 2009;32(1):193-203.
Humalog is a registered trademark of Eli Lilly and Company.
NovoLog is a registered trademark of Novo Nordisk A/S.
V-Go is a registered trademark of Valeritas, Inc.
ART-116 Rev: E
02/2014
© 2014 Valeritas, Inc.

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