Dr. Z. Jeff Daskalakis, M.D., PhD., FRCPC Dr. Daskalakis is

Dr. Z. Jeff Daskalakis, M.D., PhD., FRCPC
Dr. Daskalakis is Professor of Psychiatry and Temerty Chair in Therapeutic Brain
Intervention at the Centre for Addiction and Mental Health.
Areas of Research
Dr. Zafiris J. Daskalakis was born and raised in Toronto. He initially started his
undergraduate studies at the University of Toronto and completed medical school at Queen’s
University in 1994. He subsequently entered the residency training in Psychiatry at the
University of Toronto which he completed in 1999. While still a resident, Dr. Daskalakis
began graduate studies in the Institute of Medical Science at the University of Toronto,
supervised by Drs. Shitij Kapur (Imaging/Psychiatry) and Robert Chen (Neurophysiology).
He completed fellowship training and his PhD in 2002 at which point he started as an
Assistant Professor at the University of Toronto. Dr. Daskalakis was promoted to rank of
Professor of Psychiatry in 2013 and is presently the Temerty Chair in Therapeutic Brain
Intervention at CAMH. With an expertise in the neurophysiology of severe psychiatric
disorders, Dr. Daskalakis’s laboratory uses magnetic brain stimulation to study the role of
cortical inhibition and plasticity as potential pathophysiological mechanisms in
schizophrenia, depression and obsessive compulsive disorder. Dr. Daskalakis also conducts
treatment studies using repetitive transcranial magnetic brain stimulation (rTMS) and
magnetic seizure therapy (MST) for refractory symptoms in these disorders. He has been a
NARSAD Lieber Young Investigator (2004, 2006) a NARSAD Independent Investigator
(2008) and holds or has held CIHR, OMHF and SSO operating awards. He has also been
awarded the Samarthji Lal Award in Mental Health Research from the Graham Boeckh
Foundation. Finally, he has over 170 peer-reviewed publications in prestigious journals such
as the Archives of General Psychiatry, Brain and the American Journal of Psychiatry and is
an editorial board member for Biological Psychiatry.
Selected Publications (out of 179 in total)
Voineskos AN, Farzan F, Barr MS, Lobaugh NJ, Mulsant BH, Chen R, Fitzgerald PB,
Daskalakis ZJ. The Role of the Corpus Callosum in TMS-Induced Interhemispheric Signal
Propagation.
Biological
Psychiatry,
2010
Nov
1;68(9):825-31.
doi:
10.1016/j.biopsych.2010.06.021. Epub 2010 Aug 12.
Farzan F, Barr MS, Levinson AJ, Wong W, Chen R, Fitzgerald PB, Daskalakis ZJ:
Evidence for Gamma Inhibition Deficits in the Dorsolateral Prefrontal Cortex of Patients with
Schizophrenia, Brain, 2010 May;133(Pt 5):1505-14.
Daskalakis ZJ, Farzan F, Barr MS, Maller JJ, Chen R, Fitzgerald PB: Long Interval Cortical
Inhibition from the Dorsolateral Prefrontal Cortex: A TMS-EEG Study,
Neuropsychopharmacology. 2008 Nov;33(12):2860-9. Epub 2008 Mar 5.
Daskalakis ZJ, Christensen BK, Fitzgerald PB, Chen R: Dysfunctional Neural Plasticity in
Patients with Schizophrenia, Archives of General Psychiatry, 2008; 65(4):378-385.
Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S: Evidence
for Impaired Cortical Inhibition in Schizophrenia Using Transcranial Magnetic Stimulation.
Archives of General Psychiatry. 2002; 59(4):347-354

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