France-Berkeley Fund F ra n c e-Berkeley Fund 2 03 Mo s es Hal l U n ivers ity o f C al iforni a, Be rke l ey Be rkeley, CA 94720-2316 http ://fbf. b er ke l ey.e du + 1. 510. 643. 5799 f bf@b erkeley.e du fa c eb o o k. com/ france be ke l ey fund Annual Report 2013-2014 M in istère d es A f faires ét ra ngè re s S ou s- d irection d e la re c he rc he et d es éch an ges sc i e nt i f i que s 2 7 , r u e d e la C o nve nt i o n CS 9 1 5 3 3 - 7 5 7 3 2 PA R I S C ED EX 1 5 +3 3 .1 .4 3 . 1 7 . 6 7 . 3 4 m ad elein e.b ou v ier- d y voire@ d ip lom at i e . go uv.f r 1 Executive Committee Marc Rolland Directeur des relations européennes et internationales et de la coopération du ministère de l’éducation nationale et du ministère de l’enseignement supérieur et de la recherche. Anne Grillo Directrice de la coopération culturelle, universitaire et de la recherche, Ministère des Affaires étrangères et du Développement international Romain Serman Consul Général, Consulat Général de France à San Francisco Clément Sanchez Professeur de Physique de la matière condensée au Collège de France et Directeur français du Fonds France-Berkeley; Member of the Academie des Sciences Minh-Hà Pham Conseillère pour la Science et la Technologie, Ambassade de France aux Etats-Unis Antonin Baudry Conseiller culturel, Ambassade de France aux Etats-Unis Nicholas B. Dirks Chancellor, University of California, Berkeley Robert Price Associate Vice Chancellor for Research, University of California, Berkeley Larry Hyman Executive Director of FBF; Professor, Linguistics Department, University of California, Berkeley Tyler Stovall Professor of History, Associate Dean of Social Sciences Carl Pennypacker Astrophysicist at UC Berkeley and the Lawrence Berkeley Laboratory Kenneth Sauer Physical Biosciences Division LBNL and Professor of Chemistry, UC Berkeley Krishna Niyogi Physical Biosciences LBNL and Professor of Plant & Microbial Biology, UC Berkeley Michelle Chang Associate Professor of Chemistry, University of California, Berkeley 2 France-Berkeley Fund Eva luat i o n Co m m i t t e e BERKELEY FRANCE Krishna Niyogi Mission Expertise internationale Co-Chair, Berkeley Evaluation Committee, UC Berkeley (dedicated evaluation committee of the French Ministry of Higher Education and Research) Kenneth Sauer Co-Chair, Berkeley Evaluation Committee, UC Berkeley Larry Hyman Executive Director of the France-Berkeley Fund, UC Berkeley Tyler Stovall Professor of History, Associate Dean of Social Sciences, UC Berkeley Carl Pennypacker Astrophysicist at UC Berkeley and the Lawrence Berkeley Laboratory Michelle Chang Associate Professor of Chemistry, University of California, Berkeley Thera Ringhofer FBF Program Coordinator, UC Berkeley Annual Report 2013-2014 3 4 France-Berkeley Fund Contents D I R E C T O R ’ S M E S S A G E ................. 6 F I N A L R E P O R T S ......................... 24 F B F H i g H l i g H t s 2013-2014 ........ 10 I N T E R I M R E P O R T S ..................... 91 C H A R T S & S TAT I S T I C S ................ 17 F U N D E D P R O J E C T S BY Y E A R ...... 126 G R A N T E E S 2014 ......................... 22 F U N D E D P R O J E C T S BY F I E L D ...... 157 D i r e c t o r ’s M e s s a g e I t gives me great pleasure to introduce the current annual report of the France-Berkeley Fund. The 2013-2014 period was a very special one of great accomplishments and of celebration: Although initial signatures date from 1993, the first FBF grants were awarded in 1994, thereby making 2014 the 20th anniversary of the Fund. The 175 attendees can attest to the excitement we all felt at the May 5 celebration of this anniversary, which featured numerous testimonials of the importance of the fund from scholars and administrators from both sides of the Atlantic and the San Francisco Bay. As indicated in the posted program (see page 14), the energizing congratulatory remarks by representatives of the French Ministry of Higher Education and Research in Paris, the French Embassy in Washington, the French Consulate in San Francisco, and the Chancellor’s Office at UC Berkeley were matched by the exciting presentations of three highly successful FBF projects, a special plaque offered by Berkeley’s Center for Information Technology Research in the Interest of Society (CITRIS) to outgoing San Francisco Consul Romain Serman, and the inauguration of the first France-Berkeley Fund Awards to Frédérick Douzet (Institut Français de Géopolitique, Université Paris 8) and Jeffrey R. Long (Chemistry, UC Berkeley) (see page 10). The ceremony in the auditorium was followed by a fabulous cocktail dinatoire poster session in the beautiful galleries of the David Brower Center, with the animated conversations amplified by Back to Earth Organic Catering and appropriately arrosées by some of the finest California wines generously supplied by the John Jordan Foundation and expertly served by Rob Davis, winemaker at Jordan Winery. This particular year our business meeting took place in Berkeley, as we alternate every other year between Paris and Berkeley. As in the past we discussed and made decisions concerning the current applications (which, as always, had been separately reviewed by colleagues in France and in Berkeley), and made arrangements for future competitions and France-Berkeley events. In all 61 applications were received. Although approximately the same number as the 64 from 2012-13, we interpret6 ed this to be strong participation, especially as applications were limited to UC Berkeley and UC Davis this year. (We are hoping that the Lawrence Berkeley National Laboratory will participate again in the very near future.) In the end we received 49 proposals from UC Berkeley and 12 from UC Davis—up from 45 and 8 last year. In the end we were able to fund 25 projects, or 41%. This brings us up to approximately 375 projects that we have been to fund since our inception, totaling over $2.25 million. This past year we were able to make these awards based on the earnings on our endowment (see page 21 of this report) and additional contributions. We again received a $50,000 contribution from Robert Price’s Vice-Chancellor for Research office, and for the sixth year a 50,000 Euro contribution from the Ministry of Higher Education and Research in France. Since funding has become more constrained in recent times, we are especially grateful to both the French Ministry and the UC Campus for their continued contributions, and especially for their enthusiastic support of our activities, which means so much to us. As will be announced later, we are currently exploring ways to make individual and business contributions easier: Since we were not able to fund all of the projects that were deemed highly worthy, we will be seeking to expand our funding capabilities and support more France-Berkeley grants in the near future. As in past years, the committees worked very hard on both sides of the Atlantic in planning and in evaluating the proposals received. First and foremost, I would like especially to recognize the efforts of our colleagues who submitted proposals as well as the reviewers in France and Northern California. The 61 submitted projects came from all aspects of scholarly endeavor: 26 France-Berkeley Fund from the Exact Sciences, 12 from the Applied Sciences, 11 from Engineering, and 12 from the Humanities and Social Sciences. As explained in our call, these projects not only bring together established senior researchers, but necessarily involve junior scholars, both postdoctoral fellows and graduate students engaged in research. The France-Berkeley Fund owes its success to a number of people. On the Berkeley side I would like again to thank Robert Price, Associate Vice-Chancellor for Research, not only for the annual contribution of that his office makes to the FBF, but also for “hands on” involvement in the activities of the fund. Both Thera and I and anyone else concerned about the FBF feel we can call on him any time, and he always comes through with invaluable suggestions and advice. As in past years, Bob attends our meetings on a regular basis, contacts people as needed, and shares his knowledge of his field and academics at UC Berkeley. This year both he and Susan Aberg went way beyond the call of duty, donating much of their time and ex- ing, for his generous support of our programs over the years. To all you Berkeley colleagues, Thera’s and my greatest thanks! On the French side the list is almost endless. Concerning first those in the United States, I would like especially to thank MinhHà Pham, the Scientific Counselor at the Washington French embassy who has taken a very deep interest in guaranteeing the success (and expansion) of FBF activities. Minh-Hà visited us on more than one occasion and was always available in person, on the phone, and on email to provide her perspective and proposals and comment on ours. Also at the embassy, we are grateful to Leah Namoune, Accountant and Administrator who assisted with logistics, particularly with respect to marking our the 20th anniversary. In addition, we thank Thomas Deschamps, (Former Attaché for Science and Technology, French Consulate, San Francisco) and Stéphane Ré (Cultural Attaché, French Consulatte, San Francisco) for their ideas and hard work on behalf of the FBF. We extend special pertise in planning the 20th Anniversary Celebration on May 5! Another equally heartfelt thanks goes out to the Berkeley members of the Executive Committee who put in considerable work evaluating proposals and providing input in general: Krishna Niyogi (Professor of Plant & Microbial Biology), Carl Pennypacker (Senior Researcher, Space Sciences), Kenneth Sauer (Professor Emeritus of Chemistry), Tyler Stovall (Dean of the Undergraduate Division, College of Letters & Sciences and Professor of History), and Michelle C. Chang (Professor of Chemistry). Finally, at Berkeley, I could not have possibly gotten through this past year without the help of Thera Crane Ringhofer, the interim Program Director, whose control of all aspects of the FBF keeps us on track at all times. Finally, I would like to thank Vice Chancellor of Research Graham Flem- thanks to Thomas, Stéphane and others at the consulate (Gilles Delcourt, Deputy Cultural Attaché, Hannah Loué, Cultural Affairs Coordinator, and Raegen Salais, Assistant to the Scientific Attaché and Translator) for the $5,000 grant—among other support—for the 20th anniversary event on May 5. Finally, our thanks and very best wishes to Former Consul General Romain Serman, who has been a strong supporter of collaborative France-Berkeley research. Turning to Paris and the other side of the Atlantic, at the Ministry of Higher Education and Research, we thank Marc Rolland, Head (Chef de Service), Yannick Le Roux, Deputy Head of the Department for Scientific Cooperation, Roger Genet, Director of the Directorate General of Research and Innovation, and Na- Annual Report 2013-2014 7 dine Van der Tol, the Program Officer for Scientific Cooperation with North America. It was a great pleasure to meet Roger, who spoke at the 20th Anniversary and Nadine, who was also able to attend. We also thank Anne Grillo, Head of Cultural, Higher Education and Scientific Cooperation at the Ministry of Foreign Affairs. We also thank Andrzej Rogulski, Assistant Director for International Relations and Nicolas Marques, Deputy head of the Department for America, North Africa and Middle East, both at the Ministry of Higher Education and Research, and also Guillaume Kasperki, Head of International Relations at the College de France, which hosts my French counterpart, Clément Sanchez (see below). This year has also been a period of transition. We acknowledge, with heartfelt thanks, the following outgoing colleagues, officers and friends who have so helped us: Chloé Mugler, Program Officer for Scientific Cooperation with North America and Western Europe at the Ministry of Foreign Affairs in Paris. We thank François Delattre, former Ambassador of France to the United States for his deep interest in the France-Berkeley Fund and similarly Romain Serman, Former Consul in San Francisco. Also in San Francisco, we acknowledge the many contributions of Thomas Deschamps, former Attaché for Science and Technology. Our deepest expression of gratitude goes out to all of the above French colleagues and supporters. We will miss you, but hope there will be other occasions which will bring us together. On the positive side, we are thrilled at the new people who are already working hard with us. First, at the San Francisco consulate, we look forward to working with Pauline Carmona, the new Consul, and Philippe Perez who has recently arrived as the As promised above, it is with great admiration that I acknowledge the extraordinary efforts and engagement of my counterpart in France, Clément Sanchez who holds the Chaire de “Chimie des Matériaux Hybrides” at the Collège de France, and who has been an extraordinary person to work with. Clément is full of ideas and always available for the long email exchange, phone call, or personal lunch meeting, most recently on August 20 at La Petite Périgourdine in Paris. Finally, I would like to reiterate three Berkeley-specific acknowledgements that were made at the 20th Anniversary celebration. First, our great thanks as always to Michelle Bertho, currently on leave as Program Director, whom Thera and I consulted on numerous occasions over this past year, as FBF has done over nearly 10 years! There are no words to express the strong gratitude we all feel. Second, we acknowledge again the 17+ years that outgoing Ken Sauer has served on the FBF advisory committee, always with extreme dedication. Not to overlook any detail, Ken even found his own successor, like-professor in chemistry, Michelle Chang, who now devotedly serves in his place. Finally, Thera Crane Ringhofer is quite simply amazing. She has been such a great Interim Program Director, a true colleague and someone on whom any distracted professor such as myself would consider him/herself lucky to rely. Thank you, Thera, for making things so easy, for assuring that everything flows naturally, and for making this past year such a great success for the France-Berkeley Fund. To Michelle, Ken, Thera, and everyone, I would like to express my gratitude in what has been an extraordinary group effort in this great year of celebration (which I hope everyone will go on to read about in this report). new Attaché for Science and Technology. In Paris, we are happy to meet Madeleine Bouvier d’Yvoire as the new Program Officer for Scientific Cooperation with North America and Western Europe at the Ministry of Foreign Affairs. We welcome Pauline, Philippe and Madeleine to the France-Berkeley Fund family! To all, thank you for 2014, and have a great 2015! 8 France-Berkeley Fund In Honor of Ken Sauer D r. Kenneth Sauer, Professor Emeritus of Chemistry at UC Berkeley and Faculty Senior Scientist at LBNL, announced this year that he will retire from the Executive and Evaluation Committees of the France-Berkeley Fund. Ken has been a faithful and tirelessly active member of the FBF Committees almost since the inception of the Fund. He recounted some of his own memories of the early history of the FBF, excerpted here: “10/25/96 I was invited to join the FBF evaluation committee by Dean Richard Buxbaum of International and Area Studies. At that time successful applicants received ca $100,000 annually. We received 50 proposals to evaluate. 1/97 At my first meeting Prof. Paul Rabinow was Chair, and Prof. Peter Sahlins was Executive Director. Committee members included Didier de Fontaine, Alain de Janvry, Morton Denn (Chemical Engineering), Sylvia Spengler (Molecular & Cellular Biology), Gunther Stent (also MCB) and William Webster (Engineering). 2/3/97 First reading of proposals 3/7/97 Second reading April Evaluation Committee meeting. I read and evaluated 6 proposals of 58 submitted. 5/16/97 Executive Committee meeting in Berkeley 2003-4 Tyler Stovall, Executive Director Michelle Bertho, Academic Coordinator Krishna Niyogi, co-chair (with me) of Evaluation Committee Following our final evaluation meeting, we were invited by Alice Waters to a special lunch at Chez Panisse. She had been a Berkeley community sponsor of the FBF activities for several years. May 2004 I attended the Executive Meeting in Paris. Kent Nagano appeared at the meeting. He was then director of the Opera in Lyon, as well as director of the Berkeley Symphony Orchestra. He had probably also previously been a community sponsor of FBF when he was in Berkeley. May 5, 2014. Celebration of 20th anniversary of FBF” Ken Sauer was honored at the 20th Anniversary Celebration, in gratitude for his many years of formative service to the FBF. He will be sorely missed in our regular meetings; we hope to stay in contact for many years to come. To read more about Prof. Sauer’s illustrious career, visit http://www2.lbl.gov/vkyachan/khsauer.html. Annual Report 2013-2014 9 France-Berkeley Fund Award T he France-Berkeley Fund Award for an Outstanding Young Scholar recognizes scholarly excellence, substantial contributions to activities sponsored by the France-Berkeley Fund, and profound commitment to advancing research relationships between France and the United States. The France-Berkeley Fund Award was presented this year for the first time. Nominations were made by project PIs, and the many outstanding candidates were considered by the FBF Evaluation Committees in France and at Berkeley, respectively. The first ever FBF awards were presented to Professor Frédérick Douzet of the Institut Français de Géopolitique, Université Paris 8, and Professor Jeffrey R. long of the Department of Chemistry, UC Berkeley. Professor Douzet’s nomination stated, “Not only does she do path-breaking research on common issues facing both countries, but I can think of no one who has done more to help other scholars and promote this type of comparative studies...It is one thing to accept a grant and produce good research. It is quite another to accomplish that and to also multiply the grant’s effects with other scholars in several countries”. Professor Long’s nomination noted that he “has maintained exceptionally strong ties with scientists in France... He is a truly outstanding early-career scientist, who is on course to change the world through his energy-related materials research, and who I believe epitomizes the spirit of the France-Berkeley Fund.” Professor Clément Sanchez of the Collège de France made the award presentations at the 20th Anniversary Celebration on May 5, 2014. The following remarks are excerpted from Professor Sanchez’ speech at the Celebration. he main purpose [of the FBF Award] was to enhance the visibility of outstanding up-and-coming researchers who carry out extraordinary work in their fields through FBF granted collaborations. This award is to recognize their work and to support and promote their success in what they do. In turn, their recognized success will also extend the global visibility of the France-Berkeley Fund. In some way they are the ambassadors of the FBF. “Upon looking at the plethora of her accomplishments throughout her career, there is no doubt why Professor Frédérick Douzet deserves this award. She is clearly a natural multitasker and passionate about her field. She has a PhD in Geography with a sub field in geopolitics, which was awarded with the highest distinction. She is currently the acting direcProfessor Clément Sanchez tor of the French Institute of Geopolitics and the Geopolitics Research and Analysis Center in Paris and was selected to be presents the FBF Awards member of the Institut Universitaire de France. “Frédérick was recently nominated as the Castex Chair of Cyberstrategy and has applied for and won an extremely impressive number of grants both in Europe and in the US. “Her book, La couleur du pouvoir (The Color of Power) was awarded two prizes in France by the Academy of Moral and Political Sciences and the Geography Society. “She has been the recipient of two FBF awards, once in 2007 when she collaborated with the Berkeley Professor of Political Science, Bruce Cain, and again in 2011, for which she colProfessor Frédérick Douzet laborated with Professor Jack Citrin also of Berkeley. receives the FBF Award “Frédérick is clearly an outstanding individual in her field who exemplifies exactly what this award should recognize.” “T 10 France-Berkeley Fund Inaugural Presentation 2014 “T he second awardee is Jeffrey long, who is a professor at UC Berkeley and a Faculty Senior Scientist at the Materials Sciences Division of the Lawrence Berkeley National Laboratory. “Jeff is in a field that is close to my heart, Chemistry. “He’s one of the leaders of molecular magnetism. Moreover, he has contributed a great deal to a field that is highly relevant to the present and future of chemistry. This field concerns the molecular design of advanced coordination polymers. He has an extremely successful publication record with over 200 articles, which have been widely cited. “He has a PhD in Chemistry from Harvard, and has carried out an impressive number of professional services, including, chair of the division of inorganic chemistry at the ACS, Associate Editor of Chemical Science, Deputy Director of one of the Research Centers of the Department of Energy, the Center for Gas Separations for Clean Energy Technologies. He also belongs to the Advisory Boards of many high-standard journals. “This FBF Award joins a long list of dozens of accolades, including previous FBF grants and scholarships within this fund. He has collaborated with dozens of teams who are always enthusiProfessor Jeffrey Long astic to work with him. receives the FBF Award “In particular, he has a very efficient collaboration with Rodolphe Clérac, CNRS Director of Research working on the campus of the University of Bordeaux. “Jeff is a brilliant and influential scientist, a creative and masterful synthetic chemist with a vision of how to move the field of molecular magnetism toward potential applications in fast and efficient computing technologies. He is on course to change the world through his energy, his passion, and his accomplishments.” The next presentation of the FBF Awards is tentatively planned for 2017. Photos (clockwise from top left): Berkeley Professors Jack Citrin and Frédérick Douzet, FBF co-PIs in 2011; Professors Clément Sanchez (French director of the FBF), Jeffrey Long, and Frédérick Douzet during the 20th Anniversary Celebration program; Clément Sanchez presents Jeffrey Long with the France-Berkeley Fund Award. Annual Report 2013-2014 11 FBF 20th Anniversary Celebration T he France-Berkeley Fund celebrated 20 years of supporting innovative bi-national research projects with a Franco-American evening of program and festivities on May 5, 2014. More than 150 grantees and friends of the FBF were in attendance. During the opening program, Professor Graham Fleming, Vice Chancellor for Research at the University of California, Berke- ley, welcomed the guests and highlighted some of the achievements of the France-Berkeley Fund since its founding in 1993. San Francisco Consul Général Romain Serman then gave greetings on behalf of the Consulate and the Embassy of France in the United States. Dr. Roger Genet, Director of the Directorate General of Research and Innovation at the French Ministry of Higher Education and Research then made remarks on the value of the bi-national collaborative research endeavors that are 12 France-Berkeley Fund M a y 5 th, 2 0 1 4 , B e r k e l e y, C A made possible by the France-Berkeley Fund. Dr. Minh-Hà Pham, Scientific Counsellor at the French Embassy in the United States followed with a report on the many bilateral scientific activities taking place under the auspices of the Embassy’s Office for Science & Technology. Three keynote speakers described their FBF-sponsored research and its wider impacts: Alexandre Bayen is a two-time FBF grantee. He is Associate Professor in the Departments of Electrical Engineering & Computer Science and Civil & Environmental Engineering at UC Berkeley. His research projects include Connected Corridors and Mobile Millennium. Ariane Zambiras is a a Fulbright Fellow in the UC Berkeley Department of Sociology, as well as a writer and public speaker. She was a major participant in a 2011 FBF grant examining the emergence of the Tea Party Movement in American politics. saul Perlmutter is a 2011 recipient of the Nobel Prize in Physics, “for the discovery of the accelerating expansion of the Universe”. A three-time FBF grantee, he is a Professor of Physics at UC Berkeley and an Astrophysicist at the Lawrence Berkeley National Laboratory. The keynote speakers were followed by the inaugural presentation of the France-Berkeley Fund Award. Professor Clément Sanchez, the French director of the France-Berkeley Fund, gave the award to Professor Frédérick Douzet of the Institut Francais de Géopolitique, Université Paris 8, and to Professor Jeffrey R. long of the Department of Chemistry at UC Berkeley. See page 10 for more information about the FBF Award and its first laureates. Annual Report 2013-2014 13 19. Social and Political Tools of Urban Cosmopolitanism 18. The Loss of French Musical Property During World War II, Post‐War Repatriations, Restitutions, and 21st Century Ramifications 17. On Shaking the Apple Tree: The revolutions of Eastern Europe 1989 and the “Arab Spring” 2011 16. Challenging Borders: A French Perspective on California’s New Urban Frontiers 15. Ancient Families...Modern Tools: Prosopography and Social Network Analysis in Archival Texts 14. Language as a Key to History 13. Toward localization in atmospheric flows 12. Oligomerization of thioglutamic acid in membrane-defined microenvironments 11. Are newborns programmed to walk on the Earth? 10. France Berkeley and Discovery of Dark Energy 9. Risk Societies and Governance in Mediterranean Climate Deltas & Flood-prone Waterscapes 8. The France-UC Vanilla Consortium: An International Collaboration for Genomic Research and Germplasm Conservation for Crop Improvement of Vanilla planifolia 7. Student Science at Synchrotrons: An International Collaboration to Prepare the Next Generation of Scientists 6. From sounds to meaning: neural representation of calls in the avian auditory cortex 5. French and US Hands-On Universe 4. Rock Mechanics + Acoustics: Helping to Understand Earthquakes, Stability and Fluid Flow 3. Action localization with sequences of movemes 2. The function of plasma membrane-associated aminoglycerolipid flippases is required for signaling competence in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae 1. Phoebe Hearst’s Cultural Legacy: Etruscan Heritage in Berkeley POSTER PRESENTATIONS Jeffrey R. Long is Professor of Chemistry at UC Berkeley. His 2007 FBF project with Rodolphe Clérac, titled “Photomagnetic Metal-Cyanide Clusters”, has led to long-term collaborations and numerous publications in the area of materials chemistry. Profs. Clérac and Long have utilized their FBF work to successfully obtain a grant by a CNRS PICS program, which will extend to 2016. Details about Professor Long’s inorganic chemistry research program can be seen at http://alchemy.cchem.berkeley.edu/. Frédérick Douzet is Professor at the Institut Français de Geopolitique of Université Paris 8. She is a two-time FBF grantee, with projects entitled “Immigration, Segregation, and Urban Tension in France and California” (2007, with Bruce Cain) and “Urban Frontiers in the Age of Globalization” (2011, with Jack Citrin). Professor Douzet has used these collaborations as springboards for further international conferences and publications. Her current research projects can be seen at www.cyberstrategie.org. FRANCE-BERKELEY FUND AWARD RECIPIENTS May 5, 2014 David Brower Center 2150 Allston Way, Berkeley 4:15 pm Commemorating Over 350 Grants Awarded Since 1994 20 TH ANNIVERSARY Welcomes You To A Franco-American Celebration Of Our THE FRANCE-BERKELEY FUND LE FONDS FRANCE-BERKELEY C���������� 20 Y���� �� B��������� C������������ Larry M. Hyman, UC Berkeley Professor of Linguistics, has served as American Director of the France-Berkeley Fund since 2010. He is also a three-time FBF grantee, with collaborations focusing on historical linguistics and the languages of Sub-Saharan Africa. Robert Price is Associate Vice Chancellor for Research and Professor of Political Science at UC Berkeley. His research and teaching interests include comparative politics and African affairs, with a special emphasis on the politics of contemporary South Africa. Costas Spanos heads CITRIS (Center for Information Technology Research in the Interest of Society) at UC Berkeley. He is also the Andrew S. Grove Professor and Chair of Electrical Engineering and Computer Sciences. Clément Sanchez is Professor of Chemistry at the Collège de France, and has served as the French Director of the France-Berkeley Fund since 2010. His work in hybrid organicinorganic materials has led to numerous applications in environment, health and energy. Saul Perlmutter is a 2011 recipient of the Nobel Prize in Physics, “for the discovery of the accelerating expansion of the Universe”. A three-time FBF grantee, he is a Professor of Physics at UC Berkeley and an Astrophysicist at the Lawrence Berkeley National Laboratory. Ehud Isacoff is Professor of Neurobiology and Director of the Helen Wills Neuroscience Institute at UC Berkeley. He is a two-time FBF grantee who employs optical methods to study signaling at neuronal connections. Ariane Zambiras is a a Fulbright Fellow in the UC Berkeley Department of Sociology, as well as a writer and public speaker. She was a major participant in a 2011 FBF grant examining the emergence of the Tea Party Movement in American politics. Alexandre Bayen is a two-time FBF grantee. He is Associate Professor in the Departments of Electrical Engineering & Computer Science and Civil & Environmental Engineering at UC Berkeley. His research projects include Connected Corridors and Mobile Millennium. Minh-Hà Pham is Scientific Counsellor at the French Embassy in the United States. Much of her academic background is in the field of entomology, and she is an international expert on insect learning and behavior, including the effects of pesticides on honey bee ecology. Roger Genet is Director General of Research and Innovation at the Ministry for Higher Education and Research. He carried out the majority of his scientific career in the field of biochemistry at the French Alternative Energies and Atomic Energy Commission. Adjourn to Poster Session and Cocktail Dinatoire Closing Remarks Larry M. Hyman, American Director, France-Berkeley Fund Robert Price, Associate Vice Chancellor for Research, UC Berkeley Costas Spanos, CITRIS, UC Berkeley Special Recognitions presented by Jeffrey R. Long, Chemistry, UC Berkeley Frédérick Douzet, Institut Français de Géopolitique, Université Paris 8 Presentation of France-Berkeley Fund Awards Clément Sanchez, French Director, France-Berkeley Fund Saul Perlmutter, Physics, UC Berkeley and Lawrence Berkeley National Laboratory Ehud Isacoff, Neurobiology, UC Berkeley Ariane Zambiras, Sociology, UC Berkeley Alexandre Bayen, Electrical Engineering & Computer Sciences and Civil & Environmental Engineering, UC Berkeley Presentations by distinguished alumni of the France-Berkeley Fund Report on Bilateral Activities Minh-Hà Pham, Scientific Counsellor at the French Embassy in the United States Remarks Roger Genet, Director of the Directorate General of Research and Innovation, Ministry of Higher Education and Research Greetings François Delattre, Ambassador of France to the United States Welcome to UC Berkeley Graham Fleming, Vice Chancellor for Research, UC Berkeley Graham Fleming is Vice Chancellor for Research and Professor of Chemistry at UC Berkeley. He is an authority on ultrafast chemical and biological processes, focusing particularly on the inter-relation and inter-complexity of energy, climate and photosynthesis. François Delattre has been the Ambassador of France to the United States since 2011. His previous positions include Ambassador of France to Canada, Consul General in New York, and Press and Communications Director at the French Embassy in Washington, D.C. PROGRAM SPEAKER INFORMATION 20th Anniversary Celebration The program was brought to a close with two special recognitions. First, Professor Costas Spanos, head of the Center for Information Technology Research in the Interest of Society at UC Berkeley, together with Professor Alexandre Bayen, presented Consul Romain Serman with an award honoring his enthusiastic support of scientific programs at UC Berkeley, including the France-Berkeley Fund. In September, Mr. Serman moved on to become the director of Bpifrance USA. Then Professor Robert Price, Associate Vice Chancellor for Research at UC Berkeley, made a speech of special recognition honoring Dr. Michelle Bertho, longtime coordinator of the France-Berkeley Fund, for her extraordinary and tireless work in building up the program and turning it into a model which has since been emulated by other such programs. Professor Larry M. Hyman, the France-Berkeley Fund’s Executive Director, then welcomed everyone to the atrium for a celebratory Cocktail Dinatoire and poster session. More than 20 teams of FBF grantees presented posters of their work, sharing information about their respective research projects and sparking ideas for new collaborations. All present enjoyed a convivial and festive evening, celebrating 20 successful years and looking forward to many more. Vice Chancellor Graham Fleming welcomes the guests Associate Vice Chancellor Robert Price honors Michelle Bertho with a bear staff Longtime FBF Committee Member Kenneth Sauer Cédric Beaume and Rudy Wenk by Dr. Beaume’s poster Nancy Peluso, Mia Fuller, and Meg Conkey Winemaker Rob Davis (Jordan Winery) Gabriela Borge and Patricia Baquedano-Lopez by their poster Jean-Marie Hombert and Roger Genet discuss Dr. Hombert’s poster Diplomats from the San Francisco Consulate carry the French flag 16 Visit our web and Facebook pages to see more 20th Anniversary photos! France-Berkeley Fund France-Berkeley F u n d s tat i s t i c s Annual Report 2013-2014 17 A p p l i c a t i o n s b y Ye a r a n d by Campus Campus 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Berkeley 26 36 43 49 54 54 46 43 65 68 45 49 Davis 11 7 20 18 21 15 20 16 12 20 8 12 LBNL 7 8 5 10 4 7 6 15 11 20 11 0 santa Cruz 3 4 7 11 16 10 16 0 0 0 0 0 TOTAL 47 55 75 88 95 86 88 74 88 108 64 61 120 100 Berkeley 80 Davis LBNL 60 Santa Cruz 40 TOTAL 20 0 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 18 France-Berkeley Fund A p p l i c a t i o n s b y Ye a r a n d b y Field of Study Field 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Applied sciences 7 12 19 22 20 25 28 20 28 32 10 12 Engineering 8 8 9 15 16 14 12 11 6 12 13 11 Exact sciences 22 22 22 34 37 25 31 32 34 47 24 26 Humanities / social sciences 10 14 25 17 22 22 17 11 20 17 17 12 TOTAL 47 56 75 88 95 86 88 74 88 108 64 61 120 100 Applied Sci 80 Engineering Exact Sciences 60 Hum / Soc Sci 40 TOTAL 20 0 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Annual Report 2013-2014 19 Applications vs. Grants Awarded Year # Applications # grants % 2003 47 18 38.29 2004 55 15 27.27 2005 75 19 25.33 2006 88 19 21.59 2007 95 20 21.05 2008 86 24 27.9 2009 88 23 26.14 2010 74 21 28.38 2011 88 23 26.14 2012 108 26 24.07 2013 64 22 34.38 2014 61 25 40.98 total since 2003 804 208 25.87 120 100 80 60 Applications Grants 40 20 0 2003 20 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 France-Berkeley Fund France-Berkeley Fund Income Fiscal Year interest LBNL VCR Office Ministère Recherche & Es Fondation Polytechnique Consulat général sF 2014-2015* $147 151 $0 $68 000 $69 100 $0 $0 2013-2014 $139 768 $0 $67 865 $67 359 $0 $5 000 2012-2013 $137 602 $50 000 $72 378 $64 290 $4 978 2011-2012 $146 759 $50 000 $48 260 $68 606 2010-2011 $154 780 $50 000 $30 000 $67 342 2009-2010 $144 403 $0 $30 000 $74 145 2008-2009 $172 100 $10 000 $30 000 $70 561 2007-2008 $142 052 $30 000 $30 000 2006-2007 $151 266 $30 000 $30 000 2005-2006 $132 446 $30 000 2004-2005 $132 801 $30 000 * Projected M a r ke t Va l u e 2007 2008 2009 2010 2011 2012 2013 2014 $4 112 431 $3 988 138 $3 040 735 $3 200 951 $3 638 823 $3 644 363 $3 832 608 $4 149 270 France-Berkeley Fund Market Value $4,500,000 $4,000,000 $3,500,000 $3,000,000 $2,500,000 $2,000,000 Annual Report 2013-2014 2007 2008 2009 2010 2011 2012 2013 2014 21 grantees 2014 Joonhong Ahn, Department of Nuclear Engineering, University of California, Berkeley Franck Guarnieri, Centre de recherche sur les Risques et les Crises, Mines Paris Tech International workshop on radiological resilience in nuclear power utilization: a new paradigm of safety Martin s. Banks, Department of Optometry and Vision Science, University of California, Berkeley Yves trotter, CNRS CERCO, University Paul Sabatier, Toulouse Binocular vision in humans & primates Leo Blitz, Department of Astronomy, University of California, Berkeley Edith Falgarone, Département de Physique, Ecole Normale Supérieure, Paris The Origin of Turbulence in Star Forming Clouds Julian Borrill, Space Sciences Laboratory, University of California, Berkeley Radek Stompor, Astroparticule et Cosmologie, CNRS/Université Paris Diderot Exploring the Universe’s Dark Sector with Current Cosmological Data Sets Siobhan Brady, Plant Biology and Genome Center, University of California, Davis Patrick Laufs, INRA, Versailles Deciphering the Transcriptional Network Controlling Leaf Margin Development in Arabidopsis thaliana and Cardamine hirsuta Neil Davies, Gump South Pacific Research Station, University of California, Berkeley Joachim Claudet, CRIOBE USR 3278 CNRS-EHPE, Université de Perpignan Modeling the Moorea Social-Ecological System (MoSES): Linking Socio-economy to Ecological Processes Mary Firestone, Department of Environmental Science, Policy, and Management, University of California, Berkeley Romain Barnard, UMR Agroécologie, INRA Dijon Response of Soil Microbial Activity to Changes in Precipitation Patterns Allen Goldstein, Department of Environmental Science, Policy, and Management, University of California, Berkeley Bernard Aumont, LISA, UMR CNRS 7583, Université Paris Est Créteil & Paris Diderot Understanding the Aerosol Composition from Oxidation of Long-chain Alkanes Using Novel Measurements and Modeling Martin Head-gordon, Department of Chemistry, University of California, Berkeley Eleonora Luppi, Laboratoire de Chimie Théorique, Université Pierre et Marie Curie, Paris Quantum Chemical Calculations of Molecular High Harmonic Generation Spectra Ronald Hendel, Department of Near Eastern Studies, University of California, Berkeley Jan Joosten, Faculté de Théologie Protestante, Université de Strasbourg How Old is the Hebrew Bible? : A Textual, Historical, and Linguistic Study Elaine Landry, Department of Philosophy, University of California, Berkeley Marco Panza, Institut d’Histoire et de Philosophie des Sciences et des Techniques, Université Paris 1 Ontological Commitment in Mathematics Kai Liu, Physics Department, University of California, Davis Dafiné Ravelosona, NanoElectronics Department, Institut d’électronique fondamentale, Université Paris Sud Tailoring Magnetic Nanostructures for Advanced Magnetic Recording Media Applications Bryan D. McCloskey, Department Chemical and Biomolecular Engineering, University of California, Berkeley Dominique Guyomard, Institut of Materials Jean Rouxel (IMN), Nantes Energy Storage Research — Understanding Interfacial Degradation Processes in Li-ion Battery Systems 22 France-Berkeley Fund g r a n t e e s 2 0 1 4 ( c o n t. ) Lev Michael, Department of Linguistics, University of California, Berkeley Françoise Rose, Laboratoire Dynamique du Langage, Université Lyon 2 The Morphological Phylogenetics of Southern Tupí-Guaraní Languages scott Moura, Department of Civil and Environmental Engineering, University of California, Berkeley Florent Di Meglio, Centre Automatique et Systèmes, Mines Paris Tech Analysis and Control of Grid-Integrated Plug-in Electric Vehicle Fleets Jeffrey B. Neaton, Department of Physics, University of California, Berkeley Fabien Bruneval, Service de Recherches de Métallurgie Physique, CEA Saclay New Methods for Excited States of Complex Open-Shell Systems from Solids to Molecules James F. O’Brien, Department of Electrical Engineering and Computer Science, University of California, Berkeley François Foure, UFR IM2AG, Université Joseph Fourier, Grenoble Real-time Simulation Methods for Interactive Surgical Simulation and Planning Per-Olof Persson, Department of Mathematics, University of California, Berkeley Benjamin Stamm, Laboratoire J. L. Lions, Université Pierre et Marie Curie Sub-cell Limiting for Shock-capturing in High-Order Discontinuous Galerkin Methods Ellen Robey, Department of Molecular and Cell Biology, University of California, Berkeley Paola Romagnoli, Centre de Physiopathologie de Toulouse-Purpan, Université de Toulouse Cross-talk between Regulatory T cells in the Thymus and its Role in Preventing Autoimmunity John Searle, Department of Philosophy, University of Californaia, Berkeley Friederike Moltmann, Institut d’Histoire et de Philosophie des Sciences et des Techniques, Université Paris 1 / ENS / CNRS The Action-Product Distinction and its Importance in Speech Act Theory and Social Ontology Nicholas Swanson-Hysell, Department of Earth and Planetary Science, University of California, Berkeley Jérôme gattacceca, Centre de Recherche et d’Enseignement de Géosciences de l’Environnement, Université Aix-Marseille Furthering Understanding of Planetary Magnetism through the Study of Magnetization in Terrestrial Tmpact Craters Taka’aki Taira, Berkeley Seismological Laboratory, University of California, Berkeley Florent Brenguier, Institut des Sciences de la Terre, Université Joseph Fourier Time-Lapse Monitoring of Stress-Induced Changes in the Seismogenic Crust Jean Walrand, Department of Electrical Engineering and Computer Science, University of California, Berkeley Patrick Loiseau, Réseaux et sécurité, EURECOM Campus SophiaTech Multi-armed Bandit Games and Applications Bin Yu, Department of Statistics, University of California, Berkeley Julien Mairal, INRIA Grenoble, LEAR Team Invariant Image Representations and High Dimensional Sparse Estimation for Neurosciences Qing Zhou, Department of Psychology, University of California, Berkeley Claire Hofer, UFR de Pschologie, Université Charles de Gaulle - Lille 3 Teacher Socialization of Children’s Emotional Competence in Early Education Classrooms: A Cross-Cultural Study Annual Report 2013-2014 23 Final Reports 24 24 France-Berkeley Fund Alejandro Aguilar & Jean-Marc Bizau .........................................................................................................................26 First absolute single-photon double photoionization cross section measurements of the fundamental 2-electron negative ion:H- Alexandre M. Bayen & Paola goatin ...........................................................................................................................28 Optimal traffic flow managemetn with GPS enabled smartphones David Chandler & Benjamin Rotenberg ......................................................................................................................31 Optimizing self-assembly of complex colloidal systems using transition path sampling Steven Conolly & Xavier Maître ..................................................................................................................................33 Aerosol deposition in the airways with phase-imaging tools for inhaled drug delivery Beverly Crawford & Denis Roland ...............................................................................................................................36 Civil society formation in political transitions: culture & identity in Latin America, Eastern Europe, and Maghreb/Machrek 1980-2011 Marla Feller & David DiGregorio.................................................................................................................................39 Dendritic processing of synaptic input in retinal interneurons Daniel Fletcher & Patricia Bassereau ..........................................................................................................................40 Mechanical induction of transcellular tunnels Jack L. Gallant & Bertrand Thirion ..............................................................................................................................42 Improving fMRI by using anatomical data to constrain functional models igor V. grigoriev & Francis M. Martin..........................................................................................................................45 Uncovering evolutionary origins & mechanisms of mycorrhizal symbiosis & wood decay machinery in forest ecosystems by comparative genomics Ehud isacoff & Nicole Ropert ......................................................................................................................................50 Optogenetic probing of the mechanisms and function of gliotransmission Sanjay Kumar & Manuel Théry ...................................................................................................................................53 Engineering and dissecting the micro-architecture of actomyosin stress fibers Stephen R. Leone & Ian R. Sims ..................................................................................................................................55 Direct measurements of reaction pathways for interstellar and planetary low-temperature chemistry Bo Liu & David Bouchez..............................................................................................................................................58 Uncovering an interactive protein network that regulates microtubule nucleation and organization for plant cell growth stephen g. louie & gérard Martinez ..........................................................................................................................60 Joint experimental and theoretical study of electron-electron and electron-photon interactions in graphene-based compounds Kunxin Luo & Delphine Javelaud ................................................................................................................................65 Hippo signaling and Ski in human melanoma development Jitendra Malik, Zaid Harchaoui & Cordelia Schmid ......................................................................................................68 Large-scale learning for image and video interpretation geoffrey Marcy & guillaume Hebrard ........................................................................................................................70 A transatlantic characterization of extrasolar planets Charles Marshall & Hélène Morlon.............................................................................................................................72 Integrating molecular phylogenies and the fossil record Stephanie L. Mudge & Antoine Vauchez .....................................................................................................................75 When theory matters: law, economics, and the scholarly production of “Europe,” 1990-2010 Véronique Munoz-Dardé & Luc Foisneau ....................................................................................................................77 A Theory of Justice forty years on Vern Paxson & Renata Cruz Teixeira............................................................................................................................80 Understanding user perspectives of internet performance Kenneth Ribet & Ariane Mézard .................................................................................................................................82 Summer graduate school: new geometric techniques in number theory Michael A. Rogawski & Jean-Pierre Mothet ................................................................................................................84 Role of D-serine in migraine John W. taylor & tatiana giraud .................................................................................................................................86 Fungal ecological genomics Jeremy W. Thorner & Robert Arkowitz .......................................................................................................................89 Requirements, molecular roles and distribution of membrane phospholipids in yeast external signal-dependent polarized growth 25 Alejandro Aguilar Advanced Light Source, Lawrence Berkeley National Laboratory Jean-Marc Bizau Final Report Institut des Sciences Moléculaire d’Orsay (ISMO), Université Paris-Sud First Absolute Single-Photon Double Photoionization Cross Section Measurements of the Fundamental 2-Electron Negative Ion: H- Start Date: May 2012 1) Describe the work accomplished, in relation to the original project description. The goal of the project was to measure the absolute single-photon double photoionization cross section of atomic negative ions of hydrogen (H-), a fundamental 2-electron system, for the study of electron correlations which are stronger in H- than in the helium atom. This measurement is also very important for astrophysics since, as H- ions are present in stellar atmospheres. To reach this goal, experimental sessions were scheduled at the SOLEIL French synchrotron radiation facility in Saint-Aubin to measure the cross section from threshold to 30 eV photon energy, and at the Advanced Light Source (ALS) in Berkeley to perform the measurements at higher energy. The measurements at SOLEIL were performed in December 2011. They revealed the existence of collisional processes forbidding the measurement during this first attempt. Nevertheless, they were essential for attempting the following experiments, allowing us to understand the problems and develop a strategy to overcome them. A first set of experiments were performed at the ALS in 2012. At the low energies, the contamination by higher order radiation from the undulator and the low cross section for the double photoionization process made these measurements extremely difficult and unreliable. Custom filters were ordered for these measurements. The filters did not performed as expected (according to manufacturer’s predictions), but first measurements gave cross section of the order of theoretical values. Since these filters did not work to obtain accurate results, the French group constructed a 4-mirror filter. This filter was tested in France and shipped to ALS. A second set of experiments were performed at the ALS in December 2013. The new filter worked properly, despite a much lower transmission than 26 expected, allowing the successful measurement of the cross section between 17 and 40 eV. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. French participants: • Francis Penent (LCPMR, Univ. ParisVI senior scientist) • Jean-Marc Bizau (ISMO, Univ. Paris-Sud, senior scientist) • Denis Cubaynes (ISMO, Univ. Paris-Sud, senior scientist) • Ségolène Guilbaud (ISMO, Univ. Paris-Sud, associate professor) • M. al Shorman (ISMO, Univ. Paris-Sud, PhD student) US participants: • Alejandro Aguilar (ALS, LBNL, Berkeley, Beamline Scientist) • Nora Berrah (Physics, Western Michigan U., Michgan, prof. – currently: Physics, U. Conn., Connecticut prof.) • Rene C Bilodeau (Physics, Western Michigan U., Michigan, Senior Research Fellow; and ALS, LBNL) • Dan Gibson (Physics, Denison U., OH, prof.) • Welsley Walter (Physics, Denson U., OH, prof.) • Ileana Dimitriu (Physics, Hobart and William Smith Colleges, Assistant prof.) 3) list all publications resulting from this project. include journal titles and issues/dates. One paper in preparation. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? While there has been a long history of collaboration between N. Berrah’s group and the French group, this project generated a larger collaborative effort with the Berkeley group. France-Berkeley Fund Alejandro Aguilar Advanced Light Source, Lawrence Berkeley National Laboratory Jean-Marc Bizau Institut des Sciences Moléculaire d’Orsay (ISMO), Université Paris-Sud Final Report First Absolute Single-Photon Double Photoionization Cross Section Measurements of the Fundamental 2-Electron Negative Ion: HThe funds were central to the successful completion of the project and allowed for the construction of new equipment and exchange of expertise necessary for the successful completion of the project. We strongly regret that future collaboration is considerably compromised by the unfortunate budgetary decision to drastically reduce the activity and staff of Atomic and Molecular Physics at the ALS (including the loss of key collaborator, Alex Aguilar). However, if the situation changes, the foundation and interest for future collaborations has now been well established. Custom filters: 1606$ 4 mirror filter transport from Orsay to ALS: 740$ Flights and 1 week mission for experiment at ALS for F. Penent and J.M. Bizau 5400$ 4 mirror filter return to France: TBD We will not solicit additional funding for this project. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We greatly appreciate the flexibility of the France-Berkeley Fund and the high efficiency of its administrators, which greatly facilitated the success of this experiment. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Annual Report 2013-2014 27 Alexandre M. Bayen Electrical Engineering and Computer Science / Civil and Environmental Engineering, University of California, Berkeley Paola goatin Final Report Sophia Antipolis – Méditerranée Research Center, Inria Optimal Traffic Flow Management with GPS Enabled Smartphones Start Date: 2012 1) Describe the work accomplished, in relation to the original project description. Part I: A Continuous Junction Model with On-ramp Buffer Hydrodynamic models have commonly been used in the literature to describe the macroscopic evolution of vehicular traffic on roads and have been successfully generalized to networks in recent years. We proposed a new junction model for highway ramps in the continuous setting and a Godunov discretization of the model for ramp metering control. The model consists of the Lighthill-Whitham-Richards traffic flow model on a junction composed of one mainline, an on-ramp, and an off-ramp, which are connected by a node. In particular, a partial differential equation (PDE) describes the evolution of the vehicle density on the mainline, and an ordinary differential equation (ODE) describes the evolution of the queue length at the onramp which is modeled by a buffer to ensure that boundary conditions are satisfied in a strong sense. The off-ramp is treated as a sink, and a priority parameter is introduced to ensure uniqueness of the solution, as well as a good representation of field experiences. The definition of the solution of the Riemann problem at the junction is based on a linear programming optimization problem. Existence and uniqueness of the solution of the corresponding Riemann problem was proved. This approach is extended to general networks. The problem is discretized using a Godunov scheme that takes into account the effects of the on-ramp buffer, and allows it to take into account the possible creation of new waves when the buffer empties. 28 Part II: Optimization of Networked PDE System via Adjoint-based Control Systems of conservation law and balance law PDEs are often useful for modeling coupling of physical dynamical systems. Such applications include supply chain systems, gas pipeline flows, and transportation networks. These systems often have actuation points, where a manager has partial control of the system and seeks to influence its behavior or performance. In the context of traffic networks, we specifically consider the use of traffic lights to improve the performance of the network and alleviate congestion. We investigated methods for controlling such networks using knowledge of the dynamics of the underlying system. The approach we developed is a systematic methodology for converting an optimal control problem with PDE network constraints (e.g., maximize throughput or minimize total travel time) into a discrete time and space finite horizon optimal control problem. Such a method allows us to calculate control schemes which not only react to current conditions in the network but also anticipate future responses in the state. We detailed the building blocks of the Godunov discretization scheme and a Riemann solver at network junctions to not only map an infinite-dimensional continuous problem into the discrete domain, but also as a way of easily deriving the first-order variation of the dynamics on the network, which is a necessary step in efficiently computing the gradient of the constrained objective with respect to the control parameters. The gradient computation is done via the adjoint-method, which we have shown to scale linearly in both computation and memory complexity with the time-horizon and network size, a property of the sparse coupling of the dynamics in the network structure. We have derived a discrete time and space model for freeway traffic networks for ramp metering traffic control using the above approach. Using a realistic and practical model France-Berkeley Fund Alexandre M. Bayen Electrical Engineering and Computer Science / Civil and Environmental Engineering, University of California, Berkeley Paola goatin Sophia Antipolis – Méditerranée Research Center, Inria Optimal Traffic Flow Management with GPS Enabled Smartphones of a 20-mile-long freeway stretch in Southern California, we have shown the approach to be robust to significant errors in estimating initial conditions, boundary conditions, and model parameters, demonstrating the highly practical and applicable nature of the work. Furthermore, we have shown the running time to be well within the realm of real-time applications for large freeway networks. Part III: Discrete-time System Optimal Dynamic Traffic Assignment (SO-DTA) with Partial Compliance for Horizontal Queuing Networks In this work, we formulate the system optimal dynamic traffic assignment problem with partial control (SO-DTA-PC), using a traffic dynamics model similar to the Cell Transmission Model (CTM), which is a Godunov discretization of the LighthillWhitham-Richards (LWR) partial differential equation (PDE) with a triangular fundamental diagram. We propose solving the SO-DTA-PC problem with the non-linear traffic dynamics and limited OD data with complete split ratios as a non-linear optimal control problem. This formulation generalizes to multiple sources and multiple destinations. There is a vast literature on optimization techniques for non-linear control problems that can be utilized to solve this problem. While gradient-based methods do not provide any guarantees of converging to the optimal solution in non-linear optimization problems, they can still be used to find local minima, and it is a common approach to use gradient descent methods with multiple start points. One of the main computational challenges in this approach is the efficient computation of the gradient, since this computation must be repeated a large number of times. We show how the structure of our dynamical system allows for very efficient computation of the gradient via the discrete adjoint method. If the state vector is n dimensional and the control vector is m dimensional, direct computation of the gradient takes O(n2m) time. The adjoint methods reduces the complexity to Annual Report 2013-2014 Final Report O(n2 + nm), but the structure of our system allows for further reduction of the complexity to O(n + m) by avoiding a matrix inversion and solving the system via backwards substitution. We also present methods to reduce the sensitivity of the convergence time to algorithm parameters such as the step size in gradient descent and coefficients of the barrier functions. It should be noted that this work currently only considers computing the optimal allocation of the cooperative agents and does not consider the corresponding response from the selfish agents. It is clear that a change in the network state will result in response by the selfish agents as in Stackelberg games. Finding the optimal control for a Stackelberg game is NP Hard in the size of the network for the class of increasing latency functions even in the case of the static problem, and it is common to use approximate strategies. We wish to extend this work in the future to consider the Stackelberg response to the SO-DTA-PC problem. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • Paola Goatin – Reasearch Scientist Inria Sophia Antipolis Méditerrénée Maria Laura Delle Monache - Doctoral Student Inria Sophia Antipolis Méditerranée Walid Krichene – Ph.D. Student, Electrical Engineering and Computer Sciences, UC Berkeley Jack D. Reilly – Ph.D. candidate, CEE Systems Engineering, UC Berkeley Samitha Samaranayake – Ph.D. Candidate, CEE Systems Engineering, UC Berkeley 3) list all publications resulting from this project. include journal titles and issues/dates. M.L. Delle Monache, J. Reilly, S. Samaranayke, W. Krichene, P. Goatin, and A. Bayen – A PDE-ODE model for a junction 29 Alexandre M. Bayen Electrical Engineering and Computer Science / Civil and Environmental Engineering, University of California, Berkeley Paola goatin Final Report Sophia Antipolis – Méditerranée Research Center, Inria Optimal Traffic Flow Management with GPS Enabled Smartphones with ramp buffer. SIAM Journal of Applied Mathematics 74(1) (2014), 22-39 More publications in review. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Numerical analysis work has been performed by the INRIA team, while control and optimization work has been performed by the UC Berkeley team, thus showing great complementarty between the expertises of the two teams. Collaboration resulted in more interactions, and leverage of the funds to get additional funds (ORESTE specific funding at INRIA) and Caltrans funds at UC Berkeley. Funds will be used for 30 future research on the same topics, as well as for integration to the Connected Corridors project. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? See attachment on funding schedule (available upon request from FBF). 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. Program is very efficient as is. Celebrations of the anniversary of the fund as recently done are extremely productive for raising the visibility of the different projects. France-Berkeley Fund David Chandler Department of Chemistry, University of California, Berkeley Benjamin Rotenberg Chimie, Université Pierre et Marie Curie, Paris Optimizing Self-Assembly of Complex Colloidal Systems using Transition Path Sampling Start Date: December 2012 1) Describe the work accomplished, in relation to the original project description. The project began with Pr. Chandler visiting Paris in December 2012. During that time, we came to appreciate that one of the possible side projects identified in the proposal offered the best opportunities for both short-term impact and longer-term collaboration. Our collaboration since that time has been devoted to that theme, namely how to gain microscopic insights from the analysis of charge fluctuations in a nanocapacitor, using molecular simulation in conjunction with a novel method of statistical analysis. To facilitate that collaboration, Dr. Rotenberg visited Berkeley twice in 2013. Nanocapacitors are considered as model systems for new classes of advanced materials, especially those that might be relevant for efficient production of energy from renewable resources. A phenomenon known as “supercapacitence” has been recently discovered, but an explanation has remained elusive. The phenomenon presents the promise of developing efficient energy storage devices and highly sensitive voltage detection devices. Dr. Rotenberg and his group had developed techniques for studying nanocapacitors with molecular simulation. Pr. Chandler and his group had developed techniques for studying large fluctuation effects in nanoscale molecular simulations. By combining the two efforts, it became possible to understand the phenomenon of supercapacitence. The first paper coming from this collaboration appeared in 2013 in Physical Review Letters. That work demonstrated the ability to combine Rotenberg’s molecular simulations with Chandler’s statistical methods of analysis. The second paper will appear a few days from now as an article featured on the cover of the Journal of Physical Chemistry. It presents the results of applying this new theoretical approach to uncover Annual Report 2013-2014 Final Report the mechanism of supercapacitence. The work demonstrates previously unsuspected heterogeneity that spontaneously emerges from the forces between electrodes and ionic liquids. This heterogeneity, in the plane of the electrode, is a broken symmetry that is responsible for large charge-density fluctuations and thus large capacitance. Underlying order parameters and simplified predictive models are under further investigation by our groups. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • Pr. David Chandler, Professor of Chemistry, University of California, Berkeley Dr. Benjamin Rotenberg, CNRS Researcher, Université Pierre et Marie Curie 3) list all publications resulting from this project. include journal titles and issues/dates. Limmer, D.T., C. Merlet, M. Salanne, D. Chandler, P.A. Madden, R. van Roij, B. Rotenberg, “Charge fluctuations in nano-scale capacitors,”, Phys. Rev. Lett. 111, 106102.1-5 (2013). Merlet, C., D. T. Limmer, M. Salanne, R. Van Roij, P. A. Madden, D. Chandler and B. Rotenberg, “The electric double layer has a life of its own,” arXiv:1404.0343 (2014) and in press in Journal of Physical Chemistry C (2014). 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Prior to this grant, Pr. Chandler had met Benjamin Rotenberg during visits to the UK (where Rotenberg had collaborators), and on a few occasions, Dr. Rotenberg had attended the annual Berkeley Statistical Mechanics Meeting. While it was 31 David Chandler Department of Chemistry, University of California, Berkeley Benjamin Rotenberg Final Report Chimie, Université Pierre et Marie Curie, Paris Optimizing Self-Assembly of Complex Colloidal Systems using Transition Path Sampling clear that the two shared some common scientific interests, the catalyst for a productive collaboration was absent until the funding of this FBF Grant. The grant nucleated and melded a team that has proved to be remarkably successful. One of the students on who participated in the joint project, David Limmer, who is now at Princeton, continues to work on related projects. Pr. Chandler’s group also continues on related projects. Dr. Rotenberg plans future visits to Berkeley, and Pr. Chandler plans future visits to Paris, both to continue the science that was initiated with the FBF support. In summary: This FBF Grant facilitated collaboration and accomplishment that would not have occurred without the grant. Both French and Berkeley groups have benefited, and related work will continue. side funding for this or related projects in the future, and if yes, from where? Final accounting of collaboration expenses: Chandler travel expenses to France $ 4318.88 Rotenberg travel expenses to UCB twice 5415.45 Publication of reprints (partial cost) 250.00 ---------------Total expenses $ 9984.33 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We are pleased to have been awarded an FBF Grant, and we have benefited from the Grant. While additional funds could have been used to good effect, the amount provided was enough to nucleate a fruitful collaboration. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional out- 32 France-Berkeley Fund Steven Conolly Bioengineering, University of California, Berkeley Xavier Maître Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS — Université Paris-Sud Aerosol Deposition in the Airways with Phase-Imaging Tools for Inhaled Drug Delivery Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. The overall goal of our FBF effort was to “cross-pollinate” research between two outstanding biomedical imaging engineering research labs. One was in the US (Conolly lab at UC Berkeley), and one in France (Luc Darrasse’s lab at the University of Paris, South). Each lab is pioneering a new biomedical imaging modality that holds great promise for the future of lung imaging. The University of Paris group is one of the strongest in the world in a new imaging technique called Hyperpolarized Gas MRI. The UC Berkeley group is one of the pioneers of Magnetic Particle Imaging (MPI). Since these new imaging modalities are too new to be commercially available, the two laboratories created their own prototype scanners. We focused on in vivo imaging of inhaled therapeutics. This is an important challenge because • Conventional non-invasive imaging methods (e.g., MRI and Ultrasound) typically fail in the lung, or these methods are too invasive (e.g., PET, CT), and • The unique physics of Magnetic Particle Imaging and Hyperpolarized Gas MRI show great promise for tracking therapies in the lungs. This is a magnetically hostile environment for conventional MRI studies, due to very short T2* in the lung from 10 ppm susceptibility variations near the air-filled alveoli. MPI is totally immune to these variations. Low-field Hyperpolarized gas is orders of magnitude more immune to these susceptibility variations than conventional MRI. The most important collaborative work occurred at the International Workshop on MPI, hosted by the Conolly lab at UC Berkeley last year. We exchanged ideas and engineering “trade secrets”. We also directly compared imaging studies in terms of sensitivity, spatial resolution and contrast. These Annual Report 2013-2014 Final Report are the most important attributes for any imaging modality. Since there is no conventional method of monitoring pulmonary treatments, perhaps our single most important output is establishing the principles for quantitatively comparing pulmonary therapy monitoring methodologies. Indeed, we hope that the commercial vendors (GE, Siemens, Philips) will begin to manufacture scanners based on our research prototypes. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • Prof. Luc DARRASSE, University of Paris-South Xavier Maitre, PhD, Research University Paris-South Prof. Steven Conolly, Full Professor and Endowed Chair, Bioengineering and Electrical Engineering & Computer Sciences. Patrick Goodwill, PhD Research Scientist at UC Berkeley Bioengineering Emine Saritas, PhD, current position: Assistant Professor, Electrical Engineering, Bilkent University, Turkey; formerly a Postdoc at the Berkeley Bioengineering lab. 3) list all publications resulting from this project. include journal titles and issues/dates. France-Side Publications Ginefri JC, Rubin A, Tatoulian M, Woytasik M, Boumezbeur F, Djemaï B, Poirier-Quinot M, Lethimonnier F, Darrasse L, Dufour-Gergam E. “Implanted, inductively-coupled, radiofrequency coils fabricated on flexible polymeric material: application to in vivo rat brain MRI at 7 T.” J Magn Reson. 2012 Nov; 224:61-70. Epub 2012 Sep 20. PMID: 23041797 Chauvet D, Marsac L, Pernot M, Boch AL, Guillevin R, Salameh N, Souris L, Darrasse L, Fink M, Tanter M, Aubry JF. “Targeting accuracy of transcranial magnetic resonance-guided high-intensity focused ultrasound brain therapy: a fresh 33 Steven Conolly Bioengineering, University of California, Berkeley Xavier Maître Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS — Université Paris-Sud Final Report Aerosol Deposition in the Airways with Phase-Imaging Tools for Inhaled Drug Delivery cadaver model.”J Neurosurg. 2013 May; 118(5):1046-52. Epub 2013 Mar 1. PMID: 23451909 Lambert S, Ginefri JC, Poirier-Quinot M, Darrasse L. “High-temperature superconducting radiofrequency probe for magnetic resonance imaging applications operated below ambient pressure in a simple liquid-nitrogen cryostat.” Rev Sci Instrum. 2013 May; 84(5):054701. PMID: 23742569 Martin L, Maître X, de Rochefort L, Sarracanie M, Friese M, Hagot P, Durand E. “Phase-contrast velocity mapping for highly diffusive fluids: Optimal bipolar gradient pulse parameters for hyperpolarized helium-3.” Magn Reson Med. 2013 Nov 11. PMID: 24407833. Tardieu M, Poirier-Quinot M, Sinkus R, Darrasse L, Maître X. “Space and phase normalisations in motion correction for magnetic resonance elastography.” Comput Methods Biomech Biomed Engin. 2013;16 Suppl 1:294-6. PMID: 23923948. Laistler E, Poirier-Quinot M, Lambert SA, Dubuisson RM, Girard OM, Moser E, Darrasse L, Ginefri JC. In vivo MR imaging of the human skin at subnanoliter resolution using a superconducting surface coil at 1.5 tesla. J Magn Reson Imaging. 2013 Dec, 31. PMID: 24382749 Kriegl R, Ginefri JC, Poirier-Quinot M, Darrasse L, Goluch S, Kuehne A, Moser E, Laistler E. “Novel inductive decoupling technique for flexible transceiver arrays of monolithic transmission line resonators.” Magn Reson Med. 2014, Apr 17. PMID: 24753115 . UC Berkeley-Side Publications Kim TN, Goodwill PW, Chen Y, Conolly SM, Schaffer CB, et al. “Line-Scanning Particle Image Velocimetry: An Optical Approach for Quantifying a Wide Range of Blood Flow Speeds in Live Animals. “PLoS ONE 7(6): e38590. Epub 2012 Jun 26. PMID: 22761686. PMCID: PMC3383695. Goodwill PW1, Saritas EU, Croft LR, Kim TN, Krishnan KM, Schaffer DV, Conolly SM . “X-space MPI: magnetic nanopar34 ticles for safe medical imaging.” Adv Mater. 2012 Jul 24;24(28):3870-7. PMID: 22988557. PMCID In Progress. Lillaney P1, Shin M, Conolly SM, Fahrig R. “Magnetostatic focal spot correction for x-ray tubes operating in strong magnetic fields using iterative optimization.” Med Phys. 2012 Sep;39(9):5567-83. PMID: 22957623. PMCID: PMC3436919. LR Croft, PW Goodwill, SM Conolly, “Relaxation in X-space Magnetic Particle Imaging”, IEEE Trans Med Imag, 31(12): 2335-42, December 2012,31. PMID: 22968211. PMCID: PMC3799947. JJ Konkle, PW Goodwill, OM Carraco-Zevallos, SM Conolly, “Projection Reconstruction Magnetic Particle Imaging”, IEEE Trans Med Imag, 32(2):338-47, February 2013. PMID: 23193308. PMCID: PMC3799838. EU Saritas, PW Goodwill, LR Croft, JJ Konkle, K Lu, B Zheng, SM Conolly, “Magnetic Particle Imaging (MPI) for NMR and MRI Researchers”, J Magn Reson, 229:116-26, April 2013. PMID: 23305842. PMCID: PMC3602323. K Lu, PW Goodwill, EU Saritas, B Zheng, SM Conolly, “Lineary and Shift-Invariance for Quantitative Magnetic Particle Imaging”, IEEE Trans Med Imag, 2013. 2013 Sep;32(9):156575. PMID: 23568496. PMCID: PMC3839681. JJ Konkle, PW Goodwill, EU Saritas, B Zheng, K Lu, SM Conolly, “Twenty-Fold Acceleration of 3D Projection Reconstruction MPI”, Biomed Eng, 2013. 2013 Dec;58(6):565-76. PMID: 23940058, PMCID In Progress. EU Saritas, PW Goodwill, GZ Zhang, SM Conolly. “Magnetostimulation Limits in Magnetic Particle Imaging”, IEEE Trans Med Imag, 2013. 2013 Sep;32(9):1600-10 PMID: 23649181, PMCID In Progress. Shapiro MG, Goodwill PW, Neogy A, Yin M, Foster FS, Schaffer DV, Conolly SM. “Biogenic gas nanostructures as ultrasonic molecular reporters”, Nat Nanotechnol, 2014 France-Berkeley Fund Steven Conolly Bioengineering, University of California, Berkeley Xavier Maître Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS — Université Paris-Sud Aerosol Deposition in the Airways with Phase-Imaging Tools for Inhaled Drug Delivery Apr;9(4):311-6. Epub 2014 Mar 16. PMID: 24633522, PMCID: PMC4023545. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The two groups met and communicated on several occasions. We bonded over the shared challenges of building prototype scanners within a University environment. This bond was a crucial cultural “link”. It may be surprising, but there are only about ten research labs in academia (world-wide) that build their own biomedical imaging scanners! Innovation appears to be universally celebrated in the media, but to be brutally frank, engineering innovation is truly only celebrated many years after success is apparent! Moreover, we made excellent progress on determining the optimal methods to track inhaled therapeutic treatments. Looking to the future, the Conolly lab is now in direct communication with a startup in North Carolina (Liquidia, Inc) and more established pharmaceutical delivery company (Nektar, San Francisco, CA). These contacts were initiated in no small part due to the FBF collaborative effort in tracking inhaled therapeutic agents. Neither lab has yet established direct government funding for this research, but this is absolutely the longer-term goal. Indeed, the Conolly lab is now collabo- Annual Report 2013-2014 Final Report rating with a drug delivery specialist at UCSF, Prof. Tejal Desai. She is one of the world’s leaders in drug delivery and she is now enthusiastic to investigate whether MPI can non-invasively track her drug delivery micro-scale devices inside small animals, and one day, inside humans. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? To continue our strong collaborative relationship, Xavier Maître and Luc Darrasse used the France-Berkeley funds to visit UC Berkeley for the 2013 International Workshop on Magnetic Particle Imaging. This was the first time the workshop had ever been held in the United States. The Conolly lab hosted the event, and had over 200 visitors from around the world to share our research with, and allowed Maître and Conolly to work together intensively. The total expenses for the trip came to approximately $4,743.12. In addition, the Conolly Lab spent funds on imaging modality supplies to further improve the collaborative work with Maître’s lab. In addition, we supported a part-time stipend and research supplies for a research scientist to develop core-nano-particles for the project to improve our imaging resolution and SNR. The total expenses for the Conolly Lab came to approximately $5,000.00. 35 Beverly Crawford Travers Department of Political Science, University of California, Berkeley Denis Roland Academy of Dijon and Director of Studies in the History of Science Centre Po (Paris) Final Report Civil Society Formation in Political Transitions: The Evolution of Culture and Identity in Latin America, Eastern Europe, and Maghreb/Machrek 1980 -2011 Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. We wrote an article comparing the Arab Spring of 2011 to the uprisings against Communist regimes in Eastern Europe, 1989. Despite the obvious vast differences—in the international environment, in the demographics of those who took to the streets, and in the actual vs. potential role of capitalism in the economies of both regions, the unfolding of the two revolutions was strikingly similar. Both were able to topple entrenched regimes which had long remained in power in the absence of political opposition. in both cases, the military stood down, refusing to use violence to quell protest, unrest, and revolution…… This assurance that the main apparatus of state violence would not act to undercut their efforts signaled to protestors that the opportunity was ripe to make moves against regimes that had lost their legitimacy in the eyes of key elites. In both cases, the powerful incitement of revolutionary action in one place ( union uprisings in Poland in 1989, and the several-months long reaction to the self-immolation of fruit-seller Mohamed Bouazizi in Tunisia in 2011) gave rise to a regional snowball effect of protestors who felt suddenly empowered to break the wall of silent dissent, organize collective action, and take steps towards their various post-revolutionary futures. Many observers have argued that the two cases cannot easily be compared: In Eastern Europe, a monolithic, secular ideology was toppled; in Egypt and Tunisia, many ideologies prevailed, and religion played a powerful role. The history of Eastern Europe was part of the wider European experience; the Middle East has been considered part of the “Global South,” and has had a complex relationship with Western powers. The influence of Gorbachev’s reforms spread to the 36 Soviet sattelite countries; in the Middle East, repressive regimes persisted. We argue, however, that the two revolutions have similar causes. Both regions suffered from economic collapse and rapid decline in the standard of living, and previous protests in both regions had economic roots; although people were still working in Eastern Europe, their wages were meaningless; foodstuffs had to be procured from garden plots and on the black market, basic services broke down, including access to heat and water, and with the economic stagnation, all citizens were affected equally. High unemployment characterized Egypt and Tunisia, and the region was characterized by vast economic inequality. Both regions suffered under repressive regimes. Civil society actually flourished in both places before the revolutions, underground in Eastern Europe, and openly in Egypt and Tunisia. Civil society activists in both regions were harshly punished when caught, but nonetheless a collective awareness of dissent, nurtured through an underground grassroots press in Eastern Europe and social media and growing community meetings in Tunisia and Egypt, grew in both regions in the years before the revolutions. Western NGOs played an important role in fanning the flames of dissent by supporting human rights and labor organizations—through the Helsinki Process in Eastern Europe, initiated in 1975, and through the Euro-Med Partnership and activist groups in Egypt and Tunisia, which began to take off after 1995. Despite this growing collective dissatisfaction and awareness of dissent, large segments of the population were quiescent, people hid their dissatisfaction until it appeared to be safe to turn against the repressive regime. During that period of what Kuran calls “preference falsification” the base of support for the regime was increasingly fragile, even among political elites. As elite loyalty weakened, despots lost their will to supress dissent, and as populations became aware of France-Berkeley Fund Beverly Crawford Travers Department of Political Science, University of California, Berkeley Denis Roland Academy of Dijon and Director of Studies in the History of Science Centre Po (Paris) Civil Society Formation in Political Transitions: The Evolution of Culture and Identity in Latin America, Eastern Europe, and Maghreb/Machrek 1980 -2011 the “self-abandonment” of the ruling powers, the “bandwagon effect” led thousands to take to the streets. We conclude that despite differences in region, culture, the international environment, conditions of repression, and approaches of the protesters to the role of capitalism and even democracy in the post-revolutionary environment, a strikingly similar confluence of forces in Eastern Europe in 1989 and Egypt and Tunisia in 2011 worked together to spark revolutions that surprised seasoned analysts, and were similar in their snowball effects, their essentially non-violent approaches, and their successful toppling of entrenched regimes. In our original project, we intended to compare the 1980s democrated revolutions of Latin America to these two cases. We saw many similarities; growing dissent and protest, essential non-violence, and self-abandonment of authoritarian regimes. We were unable to complete this last case. In March 2012, Professor Rolland took on the position of Rector of March 2012 of the Academy of Guyana, and his administrative duties did not allow him the time to focus on this part of the joint project. In fact, the two cases that we did complete are quite large, and we have only just completed writing up our findings. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • Benjamin Shaub, undergraduate student,UCB Simele Rodrigues, Ph.D Candidate, University of Strasbourg Mariejo Ferreira, post-doctoral researcher, Political Studies Institute in Poitiers, France 3) list all publications resulting from this project. include journal titles and issues/dates. “On Shaking the Revolutionary Apple Tree: Eastern Europe 1989, Arab Spring 2011” submitted to Comparative Political Studies Annual Report 2013-2014 Final Report 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? During June and July 2013, Professor Crawford was in residence in France to write a joint conceptual framework for the project. Rolland and Crawford worked together in Berkeley in August 2013 on the framework. Throughout 2013-14, we researched and wrote up our findings. We will continue to work on this project together. The result will be a book that includes the case of Latin America. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? We spent FBF funds on travel, and lodging, for collaboration. Crawford conducted interviews in the former GDR and in the Czech Republic. Our Skype phone conversations and collaborative writing were provided free of charge by our universities’ infrastructure. We are soliciting outside funding for Seminars at the Berkeley EU Center of Excellence/Seminar Sciences Po, Centre d’histoire/Centre d’études des relations internationales (CERI) in Paris, the FARE laboratory in Strasbourg. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We are grateful to FBF for funding this important project. The flexibility of the France-Berkeley Fund has been key to the success of this program, since we extended our project for one year due to Professor Rolland’s new role and responsibilities as a university and institute Rector. This project has helped strengthen the relationship between the Sciences Po, the University of Strasbourg, and the Institute of European 37 Beverly Crawford Travers Department of Political Science, University of California, Berkeley Denis Roland Academy of Dijon and Director of Studies in the History of Science Centre Po (Paris) Final Report Civil Society Formation in Political Transitions: The Evolution of Culture and Identity in Latin America, Eastern Europe, and Maghreb/Machrek 1980 -2011 Studies at UC Berkeley. Both Professor Rolland and Professor Crawford have given lectures on this topic at the European 38 University of Viadrina and the Free University in Berlin, Germany. France-Berkeley Fund Marla Feller Molecular & Cell Biology, University of California, Berkeley David DiGregorio Institut Pasteur, Paris Dendritic Processing of Synaptic Input in Retinal Interneurons Start Date: December 2012 1) Describe the work accomplished, in relation to the original project description. The project proceeded remarkably close to the original proposed timeline and goals. Anna Vlasits, a graduate student in the Helen Wills Neuroscience Program visited Institut Pasteur for two separate 6 week visits to conduct experiments in collaboration with Drs. Alex tran-Van-Minh and Digregorio. The data gathered during this time was presented at the Gordon conference entitled “Dendrites: Molecules, Structure & Function” which was held May 18-24, 2013 in Les Diablerets, Switzerland and at the Annual Biophysical Society Meeting, February 15-18, 2014 in San Francisco, CA. Dr. DiGregorio traveled to UC Berkeley to consult on microscopes here that would allow for us to continue some aspects of the experiments. Dr. Tran Van Minh also visited the lab after the Biophysical Society meeting to consult on methods for conducting voltage-sensitive dye imaging experiments. These experiments are ongoing in the Feller lab at Berkeley. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • Marla Feller, Professor, UC Berkeley David Digregorio, Associate Researcher, Pasteur Institut Anna Vlasits, Ph. D. student in the Helen Wills Neuroscience Institute Graduate Program, UC Berkeley Alexandra Tran-Van Minh, postdoctoral researcher Pasteur Institut Annual Report 2013-2014 Final Report 3) list all publications resulting from this project. include journal titles and issues/dates. No publications yet, but 2 conference abstracts. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The project has generated a productive collaboration between these two individual labs. It has provided Anna an opportunity to conduct her research using state-of-the-art neurophysiology and imaging methods and has provided Alex with training in visual system neurophysiology. In addition, during Dr. DiGregorio’s visit to UC Berkeley, he gave a seminar that was extremely well attended and met with several faculty to discuss current research. At least one addition collaboration of Dr. DiGreorio and another MCB faculty is starting as a result of that. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Final accounting: Anna – trip 1 to Paris – travel + lodging $2200 Anna – trip 2 to Paris – travel + lodging $2300 David – trip to UC Berkeley $1600 Reagents (caged glutamate) $2900 Anna Vlasits has used the preliminary data to apply a predoctoral fellowship from National Institutes of Health. We just heard that she received it! It is likely to contribute to the renewal of my RO1 from NIH. 39 Daniel Fletcher Bioengineering, University of California, Berkeley Patricia Bassereau Final Report Laboratoire Physico-Chimie, Institut Curie Mechanical Induction of Transcellular Tunnels Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. The goal of this project is to determine the physical factors that influence the formation of transcellular macroaperture tunnels in endothelial cells. These tunnels have been observed in cells that were exposed to bacterial toxin such as EDIN and C3 and they serve as entry sites for pathogens to invade the underlying basement membrane and tissue. The mechanism by which the toxin induces macroaperture formation is still not well understood. However, the EDIN and C3 toxins have been previously shown to disrupt the activity of myosin, which is necessary for the cytoskeletal integrity of the cells. Disruption of the cytoskeleton is believed to increase the likelihood that the dorsal and ventral membranes of the cell come into contact and fuse to form a transcellular tunnel. We hypothesized that these macroapertures can be generated through external mechanical forces that physically bring the two membranes in close apposition to each other. To test this hypothesis, we used atomic force microscopy (AFM) to apply localized mechanical forces and combined this technique with total internal reflection fluorescence (TIRF) microscopy to visualize the formation of a macroaperture in the cell. Briefly, a tipped AFM cantilever was used to indent a spread cell for a fixed time and retracted while the cell was imaged at 2 second intervals with TIRF. The cells were stained with a membrane dye to detect opening of transcellular tunnels. The minimum force required to generate macroapertures was determined by increasing the applied force in a stepwise manner until a macroperture was formed. We performed our experiments on human endothelial vascular endothelial cells (HUVECs), which have been previously found to form transcellular tunnels when exposed to EDIN/C3 toxin. We intro40 duced the toxin to the cells by adding the toxin to the media or by expressing the toxin in the cells by transfection. We demonstrated that mechanical forces are sufficient to induce the formation of transcellular macroaperture tunnels in HUVECs in the absence of toxin. We observed localization of the I-BAR domain of MIM and actin around the edges of the macroaperture, similar to toxin-induced macroapertures. By quantifying the forces used to induce macroaperture formation, we found that cells that have been exposed to the EDIN/C3 toxin formed macroapertures at much lower forces than cells that were not exposed to the toxin. We also found that macroapertures could be induced with less force and higher frequency in cells that had minimal actin cytoskeletal structure. Our results are consistent with previous studies that highlight the importance of cytoskeletal integrity in maintaining cell shape and the role of EDIN/C3 in disrupting the cytoskeleton to induce macroapertures. To determine if mechanically-induced macroapertures are dependent on cell adhesion, we indented cells that were plated on coverslips that were coated with different extracellular matrix (ECM) proteins – gelatin and fibronectin. Our preliminary findings suggest that ECM does not significantly affect macroaperture formation in HUVECs. Since substrate stiffness has been shown to influence cell mechanics, we sought to determine if macroaperture formation is also dependent on stiffness. We plated HUVECs that were transiently expressing EDIN on fibronectin-coated polyacrylamide gels of different stiffnesses and measured the average number of apertures per cell. We found that more cells formed macroapertures when they were cultured on a stiff substrate compared to a soft substrate. We also observed a positive correlation between cell spread area and the number of macroapertures per cell. Our findings support a previously proposed model that thinning of the cells due to increased spread area could increase the likelihood of fusion France-Berkeley Fund Daniel Fletcher Bioengineering, University of California, Berkeley Patricia Bassereau Laboratoire Physico-Chimie, Institut Curie Mechanical Induction of Transcellular Tunnels between the dorsal and ventral membranes to generate macroapertures. In summary, the results from our work show that transcellular macroaperture tunnels can be initiated by mechanical force, thus highlighting the physical nature of this membrane fusion process. Our study also suggests that the cytoskeleton could provide resistance against spontaneous formation of macroapertures, a mechanism that could be hijacked by bacterial pathogens to breach the protective endothelial barrier. We successfully accomplished the original goals of our France-Berkeley proposal, and this work has inspired new research on the mechanics of membrane-membrane interactions. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • • Kevin Webster – PhD student (UC Berkeley) Caroline Stefani – PhD student (Nice) Win Pin Ng – PhD student (UC Berkeley) Carmen Chan – PhD student (UC Berkeley) Coline Prévost – PhD student (Curie Institute) Patricia Bassereau – Professor (Curie Institute) Emmanuel Lemichez – Professor (Nice) Daniel Fletcher – Professor (UC Berkeley) 3) list all publications resulting from this project. include journal titles and issues/dates. Publications resulting from this collaboration are still in preparation. Final Report ships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Support from the France-Berkeley Fund was essential for creating this collaboration and providing the opportunity for Dr. Patricia Bassereau and Caoline Stefani to visit UC Berkeley for an extended period to begin the experimental work. We have continued discussions regarding experimental priorities and results, and we plan to complete a joint paper describing the findings supported by this grant. The flexibility of the France-Berkeley Fund in supporting travel, housing, and supplies, as needed for the project, was very important for the success of this project. We do hope to continue collaborating on future membrane reconstitution projects. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? The majority of funds have been expended to enable collaborators to bring samples and visit the Berkeley campus, where the experiments are conducted on a customized AFM-TIRF system. A modest amount of funding ($2500) remains to cover supplies costs for completion of the planned experiments. We anticipate that the full funding amount will be expended by the end of the project. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We sincerely thank the France-Berkeley Fund for making this collaboration possible. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relation- Annual Report 2013-2014 41 Jack L. Gallant Psychology, University of California, Berkeley Bertrand Thirion Final Report Parietal Team, INRIA Saclay-Île-de-France Improving fMRI by Using Anatomical Data to Constrain Functional Models Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. From anatomical to functional connectivity Some experiments conducted on both sides (see e.g. [1]) convinced us that the use of anatomical connectivity as measured by diffusion MRI to inform functional MRI multivariate models was rather premature, especially in the short timeline of the project. For this reason, we decided to to shift the focus of this project from anatomically informed to models to purely functional models of brain connectivity and function that incorporate functional covariance information. Improvement of encoding models through low-rank constraints The analysis of fMRI data in response to stimuli is often divided into the two categories of forward (encoding) and backward (decoding) models. Whereas forward or encoding models are intended to model brain activity as a function of the stimulus, backward or decoding models attempt to infer the stimulus from brain activity. Both paradigms are useful in fMRI data analysis, but solve different problems and have different advantages and drawbacks. In their purest forms, both of them are inherently univariate in their dependent variable, i.e. forward models use a stimulus-dependent design to predict activity in every target voxel separately and backward models use brain activity to predict every target property of the stimulus separately. While both of these approaches already yield remarkable results, they do not take into account the covariance structure of the dependent variables. Here we concentrate on linear forward models and examine a potential way of incorporating the dependent variable covariance structure in the analysis in order to improve model performance. Note that linear models are fully separable in their dependent variables. Hence, taking into account depen42 dencies between dependent variables can only be realized at training time. Predictions of held-out responses, however, are not affected by the constraints of inter-target dependencies. One possibility for taking into account covariance in the neighborhood structure is to encode it as a penalty acting on differences in model weight maps between neighbors, as encoded by a neighborhood graph. This can be achieved, e.g. by solving a multitask ridge regression problem on the neighborhood indicator graph. Using a low-rank penalty leads to global systematic increases in predictive power, most likely due to elimination of voxel-independent noise due to implicit smoothing. However, though this method may improve denoising, it may be detrimental to the modeling of the signal. Neighboring voxels may have dissimilar responses, and forcing voxels to have similar activations to their neighbors may result in imposing a constraint that deviates from the ground truth. One potential remedy to this problem is to allow activations of chosen regions to vary freely in a subspace that is smaller than the original feature space. The choice of this shared subspace is data- driven. Making the number of dimensions in the shared subspace smaller than the number of dependent variables projected to it reduces noise and results in an optimal subspace for signal modeling. This analysis is still a work in progress, but it will be completed and published soon. Several angles of analysis can be chosen. The main question we ask in this report is “Does enforcing local neighborhoods to draw predictions from the same subspace of feature space, but varying freely within this subspace, improve predictive accuracy?”. The evaluation of this question needs to take into account that the answer may vary spatially across the brain, with respect to the region size on which this type of claim can hold and dimensionality of the subspace for which this claim can hold. For a fixed set of regions, one may identiFrance-Berkeley Fund Jack L. Gallant Psychology, University of California, Berkeley Bertrand Thirion Parietal Team, INRIA Saclay-Île-de-France Improving fMRI by Using Anatomical Data to Constrain Functional Models Final Report Fig. 1. Flat maps showing best improvement in correlation score over ranks for a radius of 6mm. Fig.2 Strongest relative improvement on 1000 best improved voxels as a function of rank for radius 12mm. Note that their absolute value is still rather low. Annual Report 2013-2014 43 Jack L. Gallant Psychology, University of California, Berkeley Bertrand Thirion Final Report Parietal Team, INRIA Saclay-Île-de-France Improving fMRI by Using Anatomical Data to Constrain Functional Models fy for each voxel which region and which subspace dimension yield an optimal prediction. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. UC Berkeley: • Jack Gallant • Alexander Huth • Natalia Bilenko INRIA: • Bertrand Thirion • Michael Eickenberg 3) list all publications resulting from this project. include journal titles and issues/dates. Michael Eickenberg, Fabian Pedregosa, Senoussi Mehdi, Alexandre Gramfort, and Bertrand Thirion. Second order scattering descriptors predict fMRI activity due to visual textures. In 3nd International Workshop on Pattern Recognition in NeuroImaging, Philadelphia, États-Unis, June 2013. Gael Varoquaux, Michael Eickenberg. Total variation meets sparsity: region-inducing penalties segment functional brain modules. Submitted to NIPS 2014. Michael Eickenberg, Alexander G. Huth, Natalia Y. Bilenko, Bertrand Thirion, Jack L. Gallant, Reduced-Rank Regression boosts the accuracy of high-dimensional encoding models. In prep. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The project has mostly consisted of graduate student visits between the two labs: mutual visits have taken place, so that 44 each partner becomes familiar with how the other partner’s lab handles data and with the main technical issues faced by each lab. Code, data and simulation programs have been exchanged between the partners (code and data: from Berkeley to Neurospin). Also, the partners have been able to compare strategies for data acquisitions (imaging parameters, processing choices). One year is short, and though starting the collaboration was fruitful, there is now more work ahead than what we have been able to achieve. For instance, the use of structured sparsity technique is interesting to both labs yet we haven’t been able to have an exchange on it. The project is thus currently a vast work in progress, and there will be continued collaboration between the partners in the future. The formalization of the collaboration within a joint grant would be well suited for that. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? The money was spent on travel and accommodation expenses for exchange visits between graduate students from each partner lab: visit of M. Eickenberg in UC Berkeley (May 2013), of A. Huth and N. Bilenko in Saclay in Nov. 2013 (one week each time). We were not able to put together an ANR-CRCNS computational neuroscience proposal last year, but wish to do so for the next call. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. 2 years rather than 1 year would be great. France-Berkeley Fund Igor V. Grigoriev Joint Genome Institute, Lawrence Berkeley National Laboratory Francis M. Martin Lab of Excellence ARBRE, Institut National de la recherche Agronomique—Nancy Uncovering Evolutionary Origins and Mechanisms of Mycorrhizal Symbiosis and Wood Decay Machinery in Forest Ecosystems by Comparative Genomics Start Date: October 2012 1) Describe the work accomplished, in relation to the original project description. Our project was focused on strengthening collaboration between LBNL, INRA, and a larger scientific community to explore associations between trees and fungi in forests. Significant progress has been achieved for each of the key objectives: 1. Strengthen collaboration between INRA and JGI (LBNL) in analysis of multi-dimensional datasets on tree-microbial interactions within the context of forest ecology and management. By developing a very strong collaboration, JGI and INRA served as crystallization centers for building very large communities of researchers interested in genomics of interactions between plants and fungi in Europe and US and developed a framework for international research in this area. Three major genomics projects with Igor Grigoriev and Francis Martin as co-PIs are funded by DOE and are in progress at JGI: Mycorrhizal Genomics Initiative, Exploring the Symbiotic Transcriptomes, and Metatranscriptomics of Forest Soil Ecosystems with 100s of genomics experiments. Several genomics projects were done across institutional boundaries, for example, several Laccaria bicolor strains, for which genomes were sequenced at JGI and transcriptomes at INRA, with both sides playing active role in data assembly, annotation, and analysis. Two genomics databases, JGI MycoCosm focused on annotated genomes and community curation and INRA Mycor Web focused on transcriptomes and community interactions, nicely complement each other. We established regular communication and working visits to exchange data and tools, experimental and computational techniques, and general expertise developed in each laboratory. Collaboration between our two institutes facilitated Annual Report 2013-2014 Final Report interactions between larger scientific communities on both sides of the Atlantic Ocean. 2. Organize several workshops to bring researchers from different disciplines to develop new resources and strategies in the framework of microbial interactions in forest ecosystems PIs of this project organized four workshops in Europe: three on Mycorrhizal genomics (Nov 2012: Nancy, France; July 2013: Leipzig, Germany; March 2014: Seville, Spain) and one on plant-fungal interactions in forest ecosystems (Nov 2012: Nancy, France) with a total of over 150 participants. Summaries of these discussions have been published (Marmeisse et al., 2013; Labbé et al., 2014). Several workshops were also organized in the US to attract new groups of researchers into international genomics initiatives: workshops in Pacific Grove, CA (March 2013), Austin, TX (Aug 2013), Walnut Creek, CA (March 2014) with a total of over 300 participants. The Mycorrhizal Genomics Consortium has grown significantly and now actively contributing to the new 1000 Fungal Genomes project, co-authored by both PIs of this project. Igor Grigoriev visited INRA Labs and other institutes in Europe, South America, and Canada to bring additional participants to study of plant –fungal interactions and extend collaboration between JGI, INRA, and other institutes. Francis Martin chaired the Asilomar Fungal Genetics Conference in 2013 and visited labs in Europe and Asia to recruit new participants for these large scale genomics initiatives. 3. Provide training opportunities and support for young researchers Martin’s lab (INRA-Nancy) hosted Alan Kuo from JGI to discuss developments in genome sequencing and annotation. Grigoriev’s lab (JGI-LBNL) hosted Emannuelle Morin from INRA at JGI for 2 weeks to train her on use of JGI annotation pipeline and support her annotation of new mycorrhizal genomes. 45 Igor V. Grigoriev Joint Genome Institute, Lawrence Berkeley National Laboratory Francis M. Martin Lab of Excellence ARBRE, Institut National de la recherche Agronomique—Nancy Final Report Uncovering Evolutionary Origins and Mechanisms of Mycorrhizal Symbiosis and Wood Decay Machinery in Forest Ecosystems by Comparative Genomics Close interactions between two teams took place at several meetings and workshops with several opportunities for talks and poster presentations for younger researchers (Asilomar Fungal Genetics Conference – March 2013, Pacific Grove, CA; JGI User Meeting - March 2014, Walnut Creek, CA; European Conference on Fungal Genetics - March 2014, Seville, Spain) 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • Igor Grigoriev, Head, Fungal Genomics Program, JGI-LBL Francis Martin, Head, Lab of Excellence ARBRE, INRANancy Alan Kuo, bioinformatics analyst, JGI-LBL Robert Riley, bioinformatics analyst, JGI-LBL Robin Ohm, bioinformatics analyst, JGI-LBL Annegret Kohler, INRA engineer, transcriptomics, INRANancy Emannuelle Morin, INRA bioinformatics engineer, INRANancy 3) list all publications resulting from this project. include journal titles and issues/dates. MARMEISSE R, NEHLS U, OPIK M, SELOSSE MA, PRINGLE A. (2013) Bridging mycorrhizal genomics, metagenomics and forest ecology. New Phytologist 198(2):343-6 LABBE J, UEHLING J, PAYEN T, PLETT J (2014) Fungal biology: compiling genomes and exploiting them. New Phytologist 203: 359–361 TISSERANT E, MALBREIL M, KUO A, KOHLER A, SYMEONIDI A, BALESTRINI R, CHARRON P, DUENSING N, FREI DIT FREY N, GIANINAZZI-PEARSON V, GILBERT B, HANDA Y, HERR J, HIJRI M, KOUL R, KAWAGUCHI M, KRAJINSKI F, LAMMERS P, MASCLAUX FG, MURAT C, MORIN E, NDIKUMANA S, PAGNI M, PETITPIERRE D, REQUENA N, ROSIKIEWICZ P, RILEY R, SAITO K, SAN CLEMENTE H, SHAPIRO H, VAN TUINEN D, 46 BECARD G, BONFANTE P, PASZKOWSKI U, SHACHAR-HILL Y, TUSKAN GA, YOUNG JPW, SANDERS IR, HENRISSAT B, RENSING SA, GRIGORIEV IV, CORRADI N, ROUX C, MARTIN F (2013) The genome of an arbuscular mycorrhizal fungus provides insights into the oldest plant symbiosis. Proceedings of the National Academy of Sciences USA Doi: 10.1073/ Pnas.1313452110 (Recommended by The Faculty Of 1000) RILEY RW, SALAMOV AA, BROWN DB, NAGY LG, FLOUDAS D, HELD BW, LEVASSEUR A, LOMBARD V, MORIN E, OTILLAR R, LINDQUIST EA, SUN H, LABUTTI KM, SCHMUTZ J, JABBOUR D, LUO H, BAKER SE, PISABARRO AG, WALTON JD, BLANCHETTE RA, HENRISSAT B, MARTIN F, CULLEN D, HIBBETT DS, GRIGORIEV IV (2014) Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/ brown-rot paradigm for wood decay fungi. Proceedings Of The National Academy Of Sciences USA, Doi/10.1073/ Pnas.1400592111 PENDLETON AL, SMITH KE, FEAU N, MARTIN FM, GRIGORIEV IV, HAMELIN R, NELSON CD, BURLEIGH JG, DAVIS JM (2014) Duplications and losses in gene families of rust pathogens highlight putative effectors. Frontiers in Plant Sciences, Doi: 10.3389/Fpls.2014.00299 NAGY L, OHM R, KOVÁCS G, FLOUDAS D, RILEY R, GACSER A, SIPICZKY M, DAVIS J, DOTY S, DE HOOG GS, LANG BF, SPATAFORA J, MARTIN F, GRIGORIEV IV, HIBBETT D (2014) Latent homology and convergent regulatory evolution underlies the repeated emergence of yeasts. Nature Communications, in press Books: MARtiN F (2013)the Ecological genomics of Fungi. John Wiley & Sons, Inc. including the following chapters: GRIGORIEV IV. A changing landscape of fungal genomics. pp 3-20. France-Berkeley Fund Igor V. Grigoriev Joint Genome Institute, Lawrence Berkeley National Laboratory Francis M. Martin Lab of Excellence ARBRE, Institut National de la recherche Agronomique—Nancy Uncovering Evolutionary Origins and Mechanisms of Mycorrhizal Symbiosis and Wood Decay Machinery in Forest Ecosystems by Comparative Genomics MARTIN F & KOHLER A. The mycorrhizal symbiosis genomics. pp169-190. MARtiN F (2014) genomics of Plant-Related Fungi. Advances In Botanical Research. Elsevier. including the following chapters: KUO A, BUSNELL B, GRIGORIEV IV. Fungal Genomics: sequencing and annotation. pp 1-52 KOHLER A & TISSERANT E. Exploring the transcriptome of mycorrhizal interactions. pp 53-78. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Although collaborations between INRA (France) and JGI/ LBNL(Berkeley, CA) started several years ago with genomics projects of the first sequenced poplar tree, its first sequenced symbionts and pathogens, this FBF funded project helped to bring this collaboration to the next level, to organize a larger community of researchers and to explore evolutionary origins and mechanisms of plant-fungal interactions in forest ecosystems using genomics approaches. These efforts have been very successful and led to new larger collaborative opportunities. Seven new genomics projects with joint participation from France and US were selected by JGI Community Science Program in 2013-2014 and in progress at JGI. One of them is the project by Martin et al. (2013) Mycorrhizal Genomics Initiative: Exploring the Symbiotic Transcriptomes (http://proposals.jgi-psf.org/pmo/proposals/978). Annual Report 2013-2014 Final Report 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? November 2012: $2,350 – travel arrangements for Igor Grigoriev to participate in 2nd Mycorrhizal workshop July 2013: $3,500 – Igor Grigoriev’s travel to 3rd Mycorrhizal workshop and visit of INRA labs March 2014: $4,150 – Emmanuelle Morin’s travel to JGI User Meeting and visit of Grigoriev’s Lab at JGI/LBNL The main publication focused on evolution of mycorrhizal and wood decay fungi is expected to be submitted to Science or Nature in summer 2014. It will be followed by a special issue of New Phytologist including several in-depth analyses of genomics data. Work on comparative analyses of a larger collection of mycorrhizal and wood decay genomes continues. We’ll seek additional funding from FBF, DOE, NSF and other funding agencies to further expand international collaboration around large-scale genomics initiatives. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We would like to thank the France-Berkeley Fund for this excellent opportunity to engage a large scientific community including the next generation of scientists into genomics research of plant-microbial interactions in forest ecosystems. 47 Ehud isacoff Molecular & Cell Biology, University of California, Berkeley Nicole Ropert Final Report Physiologie Cérébrale, Université Paris Descartes Optogenetic Probing of the Mechanisms and Function of Gliotransmission Start Date: December 2012 1) Describe the work accomplished, in relation to the original project description. The objectives of the project were the following: 1) To extend our repertoire of optogenetic tools to activate astrocytes to newly developed light-controlled versions of the glutamate-gated G protein coupled receptors (GPCR) of the mGluR family (LimGluR); 2) To develop new viral constructs and transgenics to express the light-gated glutamate receptor (LiGluR) and LimGluRs along with genetically encoded Ca2+ indicators in astrocytes of intact mouse brain; 3) To study the impact of gliotransmission on neurotransmission in cortical brain slices. 1) Developing new glutamate-gated GPCR to activate astrocytes. Several new LimGluRs have been made and their ability to modulate neuronal activity has been demonstrated both in vitro and in vivo at Berkeley by the team of Ehud Isacoff [1]. The ability of the LimGluR to modulate astrocyte activity has been tested at Paris Descartes by the team of Nicole Ropert. The effect of LimGluR photoactivation on cAMP level has been demonstrated in cultured astrocytes using total internal refection fluorescence (TIRF) microscopy. It has also been shown that LimGluR photoactivation modulate the glutamate transport by the astrocytes in culture (Li et al., manuscript submitted). 2) Specific targeting of reporter genes to astrocytes in situ. The team of Nicole Ropert at Paris Descartes has tested several viral and transgenic approaches to express specifically reporter genes in the astrocytes of adult mouse cortex. The conditional Cre-Lox strategy was validated by using, first, intracortical injection of flexed adeno-associated virus (AAV-flexed-EGFP) in GLAST-CreERT2 and Cx30-CreERT2 mice 48 to express specifically EGFP in astrocytes, and second, by crossing Cre-dependent GCaMP3 expressing mouse with the same Cre mice. Our experiments show that the transgenic approach should be favored to express reporter genes bigger than the packaging capacity of the AAV vector, and to avoid reactive astrocytes induced by AAV injections (manuscript in preparation). 3) Communication between astrocytes and neurons. The release of neuroactive gliotransmitter relies on astrocytic Ca2+ rise however the exact relation between Ca2+ signals and gliotransmitter release is far from been understood. In particular understanding how the various sources of Ca2+ (transmembrane Ca2+ influx, transmembrane Ca2+ transport, and Ca2+ release from internal stores) contribute to the release of the various gliotransmitters (glutamate, ATP, adenosine, D-serine, GABA), is still enigmatic. To address this question, we want to record astrocytic Ca2+ signals and study their impact on neuronal activity by mimicking the Ca2+ signals using light-gated Ca2+ permeable channels and receptors. Previous studies using membrane-permeable chemical Ca2+ indicators which label both neurons and astrocytes could not report Ca2+ signals from the thin astrocytic processes. Preliminary results from the team at Paris Descartes using a genetically encoded Ca2+ indicator, GCaMP3, showed that it is a very valuable tool to monitor Ca2+ activity in the thin glial processes in situ using acute cortical slices and two-photon microscopy. By crossing the Cre-dependent GCaMP3 mice with either GLAST-CreERT2 or Cx30-CreERT2 mice, we specifically labeled cortical astrocytes and monitored Ca2+ activity in the thin glial processes in response to metabotropic and ionotropic purinergic agonists. Our results demonstrate that previous experiments by monitoring only the somatic region of astrocytes have only seen the upper part of the iceberg, and they have underestimated the effects of ATP and adeFrance-Berkeley Fund Ehud isacoff Molecular & Cell Biology, University of California, Berkeley Nicole Ropert Physiologie Cérébrale, Université Paris Descartes Optogenetic Probing of the Mechanisms and Function of Gliotransmission nosine on astrocyte Ca2+ signaling in the thin processes (manuscript in preparation). The team of Nicole Ropert has demonstrated that the photoactivation of a light-gated Ca2+-translocating channelrhodopsin (CatCh) triggers reliable Ca2+ rise in cultured astrocytes [2]. CatCh is a smaller protein than LiGluR or LimGluR therefore it can be inserted into the AAV vector together with a fluorescent protein. Therefore we will test the effect of CatCh photoactivation using, first, a flexed-CatCh-AAV construct, and, second, a Cre-dependent CatCh mouse line. We have established a holographic system to shape the photoactivation according to the local events recorded in the GCaMP3-expressing mice. The impact of the light-gated astrocytic Ca2+ signals on neuronal activity will be studied using patch-clamp electrophysiological recordings. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • Nicole ROPERT, PI, DR2 CNRS Dongdong LI, CR1 INSERM Karine HERAULT, Engineer INSERM Elke SCHMIDT, PhD student, Ecole Doctorale Frontières du Vivant (Defense end of 2014) 3) list all publications resulting from this project. include journal titles and issues/dates. 1. Levitz et al, 2013, Optical control of metabotropic glutamate receptors, Nature Neuroscience V16 p507-516 2. Li et al, 2012, Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release, Journal of Physiology V590 p855-73 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationAnnual Report 2013-2014 Final Report ships between French institutions and UC campuses. Will future collaboration occur as a result of this project? A major puzzle in neurobiology is: what do glia do in the brain? Why are there so many astrocytes? Why are they so intimately interdigitated with neuronal synapses? Why do they respond to and release transmitters? The collaboration between Berkeley and Paris Descartes has been essential to apply new optogenetic tools to study in a specific manner the communication between the major class of synapse-associated glia—astrocytes--and neurons. The work followed on the heels of a sabbatical of Isacoff in Paris where his lab’s first optogenetic tools were used: ones that are foreign to astrocytes, but powerfully control an aspect of their function. But the real goal was to get optogenetic control over the natural astrocyte receptors. That was the plan of the FBF collaboration. It succeeded, by generating the first light-controlled astrocyte glutamate receptors, the mGluRs. The first of these was used in astrocytes by the Ropert group and provided key evidence for the biological role of one class of cell signaling event in astrocytes that could affect the function of nearby neurons and thereby the operation of the circuit in which they are embedded. The collaboration will continue in the next few years with an exchange of trainees and visits by Isacoff and Ropert to each other’s labs. The goal: to carry out the next set of experiments in the live mouse brain. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? The funds were spent on supplies in the Isacoff lab that were used to generate the optogenetic tools, their delivery methods, and functionally assess these. These were then supplied to the Ropert lab. An Excel file [obtainable upon request from the FBF office] lists the purchases. 49 Ehud isacoff Molecular & Cell Biology, University of California, Berkeley Nicole Ropert Final Report Physiologie Cérébrale, Université Paris Descartes Optogenetic Probing of the Mechanisms and Function of Gliotransmission On the strength of the progress supported by FBF, the Isacoff lab applied for and received funding of 2 grants that are part of the federal BRAIN Initiative: A 2-year grant from NSF-EAGER (IOS-1451027) ($100K per year, direct) and a 50 3-year grant from NIH (U01 RFA-NS-14-008) ($225K per year, direct). This funding will support parallel studies on glial-neuron interactions in zebrafish and support the continued effort on the mammalian system in collaboration with Ropert. France-Berkeley Fund Sanjay Kumar Bioengineering, University of California, Berkeley Manuel Théry Physics of Cytoskeleton and Morphogenesis, CEA Grenoble/Hopital St. Louis, Paris Engineering and Dissecting the Micro-Architecture of Actomyosin Stress Fibers Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. This project had two goals: To eludicate relationships between: (1) Actomyosin stress fiber (SF) length and SF mechanics; and (2) SF location and SF mehcanics. Both aims heavily leveraged single-cell photopatterning technologies from the Théry Lab in France and femtosecond laser nanosurgery from the Kumar Lab at UC Berkeley. Our first goal with this project was to successfully translate the photopatterning technology from the Théry Laboratory to the Kumar Laboratory. Thanks to close communication and data sharing, as well as Dr. Théry’s FBF-supported visit to the US in December 2012 and our encounters at various scientific meetings, we successfully accomplished this within the first 6-9 months. Since then, the Kumar Laboratory has been combining these patterning approaches with femtosecond laser nanosurgery to address both aims. We have made significant progress on Aim 1, having created patterns that give rise to SFs spanning a range of well-controlled lengths and applied nanosurgery to characterize the viscoelastic properties of these SFs. We are currently in the stages of verifying our preliminary data, which we plan to present publicly for the first time at a Gordon Research Conference (GRC) in June 2014. We are also beginning to make progress on Aim 2, where we have focused on designing patterns that place SFs at the center or periphery of the cell with the goal of asking whether this location influences SF mechanics and contributions to traction force and shape stability. In previous work, we had shown that these two SF locations are associated with very different viscoelastic properties, which in turn are regulated by different cellular signaling systems. Thus, this work may offer the opportunity to connect molecular events to more micro- and macroscale Annual Report 2013-2014 Final Report events. At present, we are generating our patterns and beginning to conduct laser nanosurgery studies. This work is being led by a third-year PhD student, who will present this work in poster form at the GRC on Signaling by Adhesion Receptors and has begun to assemble high-quality data towards a publication. Notably, this student was also recognized with a prestigious HHMI International Predoctoral Fellowship based in part on data and ideas associated with this project. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. UC BERKELEY • Sanjay Kumar, Associate Professor • Elena Kassianidou, Doctoral Student CEA GRENOBLE/HOPITAL ST. LOUIS • Manuel Théry, Group Leader • Timothée Vignaud, Doctoral Student 3) list all publications resulting from this project. include journal titles and issues/dates. While we have a publication in preparation, we do not yet have one accepted. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? This work would not have been possible without transfer of technologies and capabilities between UC Berkeley and CEA Grenoble. Specifically, through close communication, exchange of protocols, and critical discussion of data, Dr. Thery’s group has helped establish a core technology in Dr. Kumar’s group that did not previously exist and promises to significantly impact research in his group for years to come. 51 Sanjay Kumar Bioengineering, University of California, Berkeley Manuel Théry Physics of Cytoskeleton and Morphogenesis, CEA Grenoble/Hopital St. Louis, Paris Final Report Engineering and Dissecting the Micro-Architecture of Actomyosin Stress Fibers Similarly, the Kumar Lab has offered its experience with femtosecond laser nanosurgery to the Théry group, which has established this technology in its lab as well. Drs. Théry and Kumar have applied for one collaborative NIH grant together and will soon be applying for another, and if these efforts are successful it will ensure continued interaction for the next few years. In addition, Dr. Kumar served as an external referee on the thesis committee of one of Dr. Théry’s PhD students and attended the defense during his visit to Grenoble and Paris in November 2013. underway and is on track to lead to a manuscript for publication. If needed, modest portions of these funds may also be used to support publication charges and/or expenses to attend scientific meetings to present project research. We are grateful to the France-Berkeley fund for allowing us a nocost extension through December 31, 2014, by which time we expect to have fully spent remaining funds. As mentioned earlier, we have applied for two NIH grants together and plan to continue actively exploring joint funding opportunities, most likely via NSF, NIH, HFSP, and the EU. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? We have expended the majority of our funds. Key expenses have included: • Travel for Kumar from UC Berkeley to Paris and Grenoble to discuss research and serve on Vignaud’s thesis committee (November 2013) • Travel for Théry from France to San Francisco to discuss research with Kumar and his laboratory members and attend the American Society for Cell Biology Meeting (December 2012) • Materials and supplies: reagents for cell culture and molecular biology, extracellular matrix proteins, photomasks, expenses associated with microfabrication and imaging We plan to expend the small remaining surplus on materials and supplies relevant to the project, which is still actively 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We are enormously grateful to the France-Berkeley Fund for supporting our research. This opportunity was particularly timely and fruitful, as we had known of each others’ work for many years and briefly met at scientific conferences, but until now lacked the resources and momentum to collaborate. The France-Berkeley Fund enabled us to launch a substantial effort that has already made enormous infrastructural and educational contributions to both laboratories and, we hope, will lead to dedicated research funding. Notably, this award has also served as a pathway for Kumar, who chairs a PhD program at Berkeley, to serve on a French doctoral defense committee. This experience has greatly helped both of us recognize and appreciate the many cultural similarities and differences between the American and French systems of graduate education and will surely influence how we approach this at our home institutions in the future. 52 France-Berkeley Fund Stephen R. Leone Chemistry and Physics, University of California, Berkeley Ian R. Sims Institut de Physique de Rennes, Université de Rennes 1 Direct Measurements of Reaction Pathways for Interstellar and Planetary Low-Temperature Chemistry Start Date: June 2012 1) Describe the work accomplished, in relation to the original project description. The project was initiated in June 2012, and ran until December 2013, with a 6-month extension. Four collaborative visits have been undertaken during the project period. The visits were organized around allocated beam time on the Chemical Dynamics Beamline at the Advanced Light Source (ALS) synchrotron in Berkeley, a large scale facility which provides tunable vacuum ultraviolet light to enable (in our case) the direct detection of the products of elementary reactions of importance for the chemistry of interstellar molecular clouds and planetary atmospheres. the first collaborative visit in June 2012 was by Prof. Sims and his graduate student Martin Fournier, partly funded by the FBF, and partly by funds from Rennes. They worked with Dr Jordy Bouwman (postdoctoral fellow within Prof. Leone’s group) and Dr Kevin Wilson (Deputy Director of the Chemical Dynamics Beamline at the ALS) on the determination of the products of elementary gas-phase reactions at low temperatures. The period was spent principally in learning how to use the instrument, and preliminary results were obtained on the reaction of the C2H radical with isomers of butene, C4H8. These reactions are of interest particularly for understanding the chemistry of the cold, dense atmosphere of Titan, one of Saturn’s moons. A second visit was undertaken in December 2012 by Martin Fournier to complete the study, and the results were analysed and interpreted in the first half of 2013, resulting in a joint publication (see [1] in question #3 below). A third visit was made by Prof. Sims to Berkeley in May 2013, this time to work with another postdoctoral fellow in Prof. Leone’s group, Dr. Jessica Lockyear. A sister instrument to the original low temperature setup was employed which has adAnnual Report 2013-2014 Final Report vanced capabilities for product detection (the capability to detect multiple products at the same time), though only at room temperature in this case. Reactions of the cyano radical CN with methanol, ammonia and 1,3-butadiene were studied, as well as reactions of the methylidyne radical CH with methanol, ethane and methyl vinyl ketone. Complementary low temperature rate constant measurements have also been performed in Rennes on the CN + methanol reaction. The results of this work are currently being analysed, and are expected to result in a number of further joint publications. The project was slightly delayed versus the original timeline owing to the shutdown of the ALS in the first quarter of 2013, and a 6-month extension to the project was requested and granted. A fourth and final extended 4-week visit was then made by Martin Fournier in November-December to work with Dr Jessica Lockyear, Dr Kevin Wilson and his postdoc at the ALS Dr Benjamin Kirk. Previous work on the products of C2H radical reactions with 1,3 butadiene, 1-butyne and vinyl acetylene suffered from unwanted dissociation of the hydrocarbon by the 193 nm UV laser used to produce the C2H radicals by photolysis of HCCH or CF3CCH. In Rennes we have developed a new, safe synthesis of bromoacetylene, BrCCH, which can be photolysed at 248 nm where the hydrocarbon precursors do not absorb and are therefore not dissociated. Thanks to the last part of the France Berkeley Fund grant, combined with support from the Université de Rennes 1 Physical Sciences Graduate School, Martin Fournier was able to bring over to the ALS the synthetic glassware, and then to visit for two runs at the ALS where he synthesised this precursor, first on the ‘kinetics machine’ where the products of the above reactions were determined at room temperature, and then on the low temperature Laval nozzle machine, where unfortunately technical issues meant that the low temperature work had to be postponed. Nonetheless, sufficient data were gathered to form the basis of one 53 Stephen R. Leone Chemistry and Physics, University of California, Berkeley Ian R. Sims Final Report Institut de Physique de Rennes, Université de Rennes 1 Direct Measurements of Reaction Pathways for Interstellar and Planetary Low-Temperature Chemistry joint publication on the products of the C2H + 1,3 butadiene reaction, proposed to form benzene in a one-step reaction in cold space environments (see [2] below), as well as several further publications in preparation. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • Professor Stephen R. Leone, Professor of Chemistry and Physics, University of California, Berkeley Professor Ian R. Sims, Distinguished Professor of Physics, Université de Rennes 1, France Dr Kevin R. Wilson, Deputy Director for Science for the Chemical Sciences Division, Lawrence Berkeley National Laboratory Dr Jordy Bouwman, Postdoctoral Researcher, Chemical Dynamics Beamline, Advanced Light Source, Lawrence Berkeley National Laboratory now at Radboud University Nijmegen, The Netherlands Dr Jessica F. Lockyear, Postdoctoral Researcher, Chemical Dynamics Beamline, Advanced Light Source, Lawrence Berkeley National Laboratory Dr Benjamin Kirk, Postdoctoral Researcher, Chemical Dynamics Beamline, Advanced Light Source, Lawrence Berkeley National Laboratory Mr Martin Fournier, PhD student, Institute of Physics Rennes, UMR 6251 Université de Rennes 1 – CNRS, Rennes, France 3) list all publications resulting from this project. include journal titles and issues/dates. [1] J. Bouwman, M. Fournier, I. R. Sims, S. R. Leone, and K. R. Wilson, Reaction Rate and Isomer-Specific Product Branching Ratios of C2H + C4H8: 1-Butene, cis-2-Butene, trans-2Butene, and Isobutene at 79 K, J. Phys. Chem. A 117 (2013), 5093-5105. 54 [2] J. F. Lockyear, M. Fournier, I. R. Sims, J. C. Guillemin, C. A. Taatjes, D. L. Osborn, and S. R. Leone, Formation of Fulvene in the Reaction of C2H with 1,3-Butadiene, Int. J. Mass Spectrom. (2014), under review. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The expertise of the Sims group in astrochemical reaction kinetics was able to be combined with the world class facilities and expert staff at the Chemical Dynamics Beamline at the ALS thanks to FBF travel assistance to bring French staff over from Rennes to Berkeley for four visits associated each time with experiments on the Beamline. The collaboration has resulted in the award of funds from the Université de Rennes 1 in part to fund further collaboration and also to assist in setting up an International Research Group (GDRI Groupement De Recherche Internationale) funded by the CNRS. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? See detailed budget on next page. We plan on requesting further support from the Université de Rennes 1 as well as the French CNRS to support these collaborations. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We would just wish to express our thanks to the France-Berkeley Fund for the award which has been very helpful and enabled a fruitful collaboration to be created between the low temperature astrochemistry group of Professor Sims and the France-Berkeley Fund Stephen R. Leone Chemistry and Physics, University of California, Berkeley Ian R. Sims Institut de Physique de Rennes, Université de Rennes 1 Direct Measurements of Reaction Pathways for Interstellar and Planetary Low-Temperature Chemistry Final Report chemical dynamics groups of Professor Stephen Leone and Dr Kevin Wilson. Date June 2012 Event Visit by Ian Sims and Martin Fournier to undertake preliminary experiments with Kevin Wilson and Jordy Bouwman at the ALS November 2012 Visit by Martin Fournier to measure C2H + butene reaction products with Kevin Wilson and Jordy Bouwma`n at the ALS May 2013 Visit by Ian Sims to the ALS to work with Jessica Lockyear on reactions of saturated species using the Sandia kinetics machine November/ December 2013 Extended visit by Martin Fournier to undertake new measurements on C2H reactions using BrCCH precursor at the ALS, working with Jessica Lockyear, Ben Kirk and Kevin Wilson Annual Report 2013-2014 item Travel for MF and IRS Amount / Us $ Covered by Université de Rennes 1 Accommodation for MF at LBL Guest House 1485.00 Airfare 1101.40 Accommodation and meals 1072.03 Airfare 1151.09 Accommodation at the Women’s Faculty Club 1231.50 Rental car etc 387.78 Meals (per diem) 840.00 Airfare 713.58 Accommodation Covered by Université de Rennes 1 Meals (per diem) 2017.42 Total 9999.80 55 Bo Liu Plant Biology, University of California, Davis David Bouchez Final Report Institut Jean-Pierre Bourgin, INRA Centre de Versailles-Grignon Uncovering an Interactive Protein Network that Regulates Microtubule Nucleation and Organization for Plant Cell Growth Start Date: July 2012 1) Describe the work accomplished, in relation to the original project description. The long-term goal of this project is to elucidate molecular mechanisms that regulate microtubule nucleation and organization during cell division and expansion in flowering plants. Because microtubules directly control essential events during plant cell growth, like chromosome segregation and cell wall patterning, they have to be organized into developmentally important arrays in spatially and temporally regulated manners. The two laboratories share common interests in dissecting regulatory mechanisms and have discovered a number of key proteins. In fact, the Bouchez laboratory focuses on genetic aspects of division plane determination in plants, while the Liu laboratory uses biochemistry and cell biology approaches to learn how microtubules are remodeled during plant cell division. Through independent studies carried out earlier, we have learned that the 8-protein complex augmin plays a critical role in the localization of the γ-tubulin complex on microtubules of different arrays, and TON1 regulates the organization of microtubules in the cortical preprophase band that marks the division plane. Specifically, we aimed to test whether augmin and TON1 interacted directly or indirectly. To date, the two laboratories have purified the augmin complex and the TON1 protein complex. It was found that the purified augmin complex did not contain proteins identified in the TON1 complex, neither were augmin proteins co-purified with TON1. Thus we concluded that these two protein complexes do not physically interact directly in vivo, and they probably regulate microtubule nucleation and organization in two distinct pathways. However, transient or labile interactions between the two complexes remain an open possibility. Alternatively, the augmin and nucleation complexes may be 56 a target for regulation by the TON1-TON2/FASS complex, by means of its protein phosphatase activity. The Bouchez group is developing an in vitro PP2A phosphatase assay that will be available for conducting activity tests on phosphorylated forms of Arabidopsis augmin, as phosphorylated forms exist for several subunits. In addition, recently results published by Kirik et al. (2012) indicated that the TON1 complex is involved in microtubule nucleation, and we have recently obtained yeast two-hybrid evidence that TON2/FASS interacts with elements of the nucleation machinery. Based on these findings, our ongoing experiments have been revised and will more likely lead to informative findings. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • Bo Liu, Professor Y.-J. Julie Lee, Associate Plant Biologist David Bouchez, Senior Scientist 3) list all publications resulting from this project. include journal titles and issues/dates. At the current stage, investigations are still underway. A relatively complete story will be developed after collecting additional data and summarized as a manuscript for a leading journal in the field of plant/cell biology. The FBF funding will be acknowledged. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Previously, the two laboratories did not have direct interactions and were known based on reading each other’s publications. Stimulated by the FBF program, colleagues from the two laboratories had face-to-face discussions. While the France-Berkeley Fund Bo Liu Plant Biology, University of California, Davis David Bouchez Institut Jean-Pierre Bourgin, INRA Centre de Versailles-Grignon Uncovering an Interactive Protein Network that Regulates Microtubule Nucleation and Organization for Plant Cell Growth two laboratories have their own emphases of proteins of interest, it became eminent that the interaction between these proteins will have to be tested via genetics and biochemical approaches expertized in the two laboratories. For example, one possibility is that the microtubule nucleation activity of the augmin complex is regulated by the TON1-TON2/FASS protein phosphatase complex through protein dephosphorylation. When additional funds become available, junior scientists can be sent to each other’s institutions in order to carry out extensive experiments aimed at testing protein phosphorylation and dephosphorylation at distinctive stages of cell division, as well as assaying how these events may affect the organization of the plant specific microtubule array called preprophase band. We look forward to strengthening future collaborations. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Funds were spent in the following categories: Annual Report 2013-2014 Final Report 1) 2) 3) 4) Molecular and cellular biology reagents $4,000 Antibody production $2,500 Recharge fees at the imaging facility $1,500 Travel $2,000 In order to expand the collaboration between the two laboratories, it would be essential to secure additional funds that would place a full-time postdoctoral fellow or graduate student on the project for a longer period of time like three years. Potential agencies for extramural funds are the Human Frontiers Science or possible future calls from joint programs at the National Science Foundation of USA and the Agence Nationale de la Recherche (ANR) of France. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. This is an excellent program that stimulates collaborations between UC laboratories and colleagues in France. It would be even more helpful if personnel cost like stipend were allowed. 57 Stephen G. Louie Physics, University of California, Berkeley gérard Martinez CNRS-LNCMI, Université Joseph Fourier Grenoble Final Report Joint Experimental and Theoretical Study of Electron-Electron and Electron-Phonon Interactions in Graphene-Based Compounds and Topological Insulators with Magneto-Optical Spectroscopy Start Date: September 2012 1) Describe the work accomplished, in relation to the original project description. As described in the original project proposal, the general goal of this project was to understand how electron-electron and electron-phonon interactions affect the electronic and optical properties of graphene-based materials and topological insulators as manifested in their magneto-optical spectra. The accomplished work is in accordance to the proposed goal, with a focus on graphene because of experimental limitations in access to high field resistive magnets. We have collected magneto-optical spectra of various graphene samples and have performed theoretical modelling and analysis of the obtained data. Our analysis reveals signatures of valley-symmetry breaking in graphene, which is a phenomenon caused by electron-electron interactions. This symmetry breaking is extensively discussed in the literature from the theoretical point of view, but has only been observed in transport measurements. Our work provides the first optical confirmation of the valley-polarized nature of the ground state. The details of the experiment and theoretical modelling are given in the attached supporting documents. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • Steven G. Louie, Professor Gérard Martinez, Professor Liang Z. Tan, doctoral student 3) list all publications resulting from this project. include journal titles and issues/dates. A manuscript is in preparation. We plan to submit it to Nature Physics or Physical Review Letters. We expect a publication 58 in a high-impact journal because this work represents the first optical observation and introduces a new theoretical perspective on an important topic of great current interest in condensed matter physics. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? We have collaborated very closely over the course of this project. There have been many fruitful discussions, particularly during the visits to Grenoble and Berkeley. These discussions have greatly increased our understanding of many-body physics in graphene, and have benefited both experimental and theoretical sides of the collaboration. We will certainly continue to work together in the future. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? An amount of $6,000 was spent on accommodation and travel expenses for two separate visits of Liang Z. Tan to Grenoble. An amount of $3,000 was spent on accommodation and travel expenses for the visit of Gérard Martinez to Berkeley. We anticipate requesting support for future activities along the direction of our France-Berkeley Fund project from the NSF. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. Our collaboration has been extremely fruitful. The travel fund provided by the France-Berkeley Fund made the success of our project possible. France-Berkeley Fund Annual Report 2013-2014 SiC: d = 32 µm 0.25 0.30 Fig. 1: Absolute transmission spectrum at B=0 T of the sample Gth3N. The spectrum reflects essentially the features related to the SiC substrate. Far infra-red magneto-optical experiments have been performed at magnetic field strengths B up to 35 T and at a fixed temperature of 1.6 K. The light (provided and analyzed by a Fourier transform spectrometer) was delivered to the sample by means of light-pipe optics. All experiments were performed with non- polarized light, in the Faraday geometry with the wave vector of the incoming light parallel to the magnetic field direction and perpendicular to the plane of the samples. A Si bolometer was placed directly beneath the sample to detect the transmitted radiation. The response of this bolometer is strongly dependent on B. Therefore, in order to measure the absolute transmission TA(B,ω), we used a sample-rotating holder and measure, for each value of B, e reference spectrum through a hole. These spectra are in turn normalized with respect to TA(0,ω) to obtain a relative transmission spectrum TR(B,ω) which only displays the magnetic field dependent features. The samples are in fact multi-layer epitaxial graphene grown on a SiC substrate. The present study required some special care because the SiC substrate develops a strong double phonon structure in absorption around the energy of interest as shown in Fig.1. Thin SiC substrates are not commercially available and , in the present case, we have been lead to thin down these substrates to thicknesses d lower than 40 µm. Gth3N K- phonon Γ- phonon 35T Fig. 2: Relative transmission spectra of the sample Gth3N for different values of the magnetic field up to 35 T. 12T 0.12 0.14 0.16 0.18 0.20 0.22 0.24 0.26 Energy (eV) 0.7 0.8 0.9 1.0 1.1 We report in Fig.2 the relative transmission spectra on sample Gth3N for different magnetic field values between 12 and 35 T. 0.15 0.20 Energy (eV) Γ phonon Among the different possibilities of investigations on such a large domain of physics, we have chosen to concentrate our studies on the observation of the interaction between electrons and the Γ phonon in Graphene. The technique consist in measuring the magneto-optical transmission spectra in the far-infrared corresponding to the transitions between Landau levels n=0 and n= ± 1 and to follow the intensity of this transition when it crosses the energy of the Γ phonon (0.196 eV). 0.10 K phonon Gth3N: B = 0 T 0.0 0.05 0.2 0.4 0.6 0.8 Experimental results: Absolute transmission Relative transmission General aspects and techniques: Experimental results Steven G. Louie and G. Martinez M.Orlita, Liang Z. Tan, M. Potemski, M. Sprinkle, C. Berger, W. A. de Heer, Joint experimental and theoretical study of electron-electron and electron-phonon interactions in graphene-based compounds and topological insulators with magneto-optical spectroscopy. France-Berkeley fund: Grant ID #: 2012-0019 Supplementary information for the final report of the 1.0 Stephen G. Louie Physics, University of California, Berkeley gérard Martinez CNRS-LNCMI, Université Joseph Fourier Grenoble Joint Experimental and Theoretical Study of Electron-Electron and Electron-Phonon Interactions in Graphene-Based Compounds and Topological Insulators with Magneto-Optical Spectroscopy Final Report 59 60 Γ phonon Energy (eV) 0.16 0.18 0.20 0.22 0.24 0.26 Gth3N 35T 34 T 33 T 32 T 31T 30 T 29 T 28 T 27 T Fig. 3: Absolute transmission spectra of the sample Gth3N for different values of the magnetic field between 27 and 35 T. A high energy component of the main line develops resulting in a splitting for largest values of the field. This occurs for energies larger than the Γ phonon energy (0.196 eV). Re(σ𝑥𝑥𝑥𝑥 (ω, B)) ε0 c A very rough treatment of the data has been first done by a de- convolution of them with two Lorentzians of equal width (but magnetic field dependent). This approach gives the following results displayed in Fig.4. The same procedure has been applied to a second sample (named S4) but only investigated up to 34 T. Therefore the spectra reflect mainly the component σxx of the conductivity. T(ω, B) ≈ 1 − β In general and for a single graphene layer on top of a substrate and in a range of energies where the substrate is non dispersive, the transmission T is given by: 1.9 1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1.0 0.9 0.8 0.7 CR energies (meV The evolution of the main lower energy line varies at low fields like B1/2 with a coefficient depending on the Fermi velocity vF and ends at higher fields with a similar dependence but with a smaller value of vF. This is by itself a sign of some interaction. The transition between the two dependences occurs at an energy corresponding to that of the Γ phonon. The second component appears at energies larger than that of the Γ phonon. In principle, in the one electron picture, it is not possible to explain the occurrence of an additional transition line at higher energies than the main transition line. It is clear that the Γ phonon plays a role in that matter though it should not! The reason why it should not is that in the simple picture for graphene with two inequivalent valleys K and K’ but with the same symmetry the electron-phonon interaction g(K)= -g(K’). Therefore, in the infra-red, the Γphonon is inactive.(And indeed we don’t see it!). As a result, the observed interaction is very likely the signature of the symmetry breaking of the n =0 Landau level as inferred from transport data2 and theoretical models3. (iv) (ii) (iii) (i) Though the procedure is quite rough, it provides some very important information. Fig. 4: Cyclotron Resonance (CR) energies, resulting from the de-convolution of the transmission traces, as a function of B1/2. Open dots :sample Gth3N and full dots : sample S4. SQRT(B) (T1/2) 230 225 Gth3: empty dots 220 S4: full dots 215 210 205 200 195 Γ phonon energy 190 1/2 185 F2(B) = 36.5*B 180 175 F1(B) = 35.85*B1/2 170 4.6 4.8 5.0 5.2 5.4 5.6 5.8 6.0 Final Report Relative transmission The relative transmission spectra display two anomalies: first, a depletion of the oscillator strength of the transition around 0.15 eV corresponding to the interaction with the K-phonon. This interaction has been previously analyzed1 and will not be discuss any longer here. A second anomaly appears for fields larger than about 27 T and results in an asymmetric broadening of the absorption line which increases with B and finally results in a splitting of this line. This is clearly seen in Fig.3. Stephen G. Louie Physics, University of California, Berkeley gérard Martinez CNRS-LNCMI, Université Joseph Fourier Grenoble Joint Experimental and Theoretical Study of Electron-Electron and Electron-Phonon Interactions in Graphene-Based Compounds and Topological Insulators with Magneto-Optical Spectroscopy France-Berkeley Fund Annual Report 2013-2014 (1) M.Orlita, Liang Z. Tan, M. Potemski, M. Sprinkle, C. Berger, W. A. de Heer, Steven G. Louie and G. Martinez , Phys. Rev. Lett., 108, 247401 (2012) (2) A. F. Young et al., Nature Physics 8, 550 (2012) (3) M. Kharitonov , Phys. Rev. B 85, 155439 (2012) References: These experiments have been done in the High Magnetic Field Laboratory of Grenoble. Besides the difficulty to obtain good quality samples, the main reason why there was such a delay between the original plan and the actual one is that the access to high field resistive magnets is very limited: one can expect in the best case to have two sets (4days) of experiments per year. We finally succeeded but it took one more year than expected. Conclusion from the experimental side. At present we are treating the experimental information on a real physical basis with the model which has been elaborated by the theory group of Berkeley. The overall agreement seems very good and the project will certainly result in a high standard publication. Results and discussion: The fitting parameters of our model are the broadening energy and the valley-symmetry breaking energy scale. The spin-splitting energy scale is fixed at the Zeeman energy. We calculate the absorption spectrum by considering transitions from the n=0 Landau level to the n=+1, -1 Landau levels. These transitions are allowed to interact with the phonons in graphene. The phonon frequency and the electron-phonon interaction are obtained from first-principles density functional theory calculations. Figure 5: Schematic of the four sublevels of the n=0 Landau level in graphene, corresponding the the valley (K/K’) and spin (red/blue) degrees of freedom. We model the n=0 Landau level of graphene as consisting of four sublevels, corresponding to the valley and spin degrees of freedom. We include symmetry breaking by allowing the spin and valley sublevels to have different energies (Figure 5.) Each sublevel is broadened by the same amount. Description of model: Theoretical analysis of data Steven G. Louie and G. Martinez M.Orlita, Liang Z. Tan, M. Potemski, M. Sprinkle, C. Berger, W. A. de Heer, Joint experimental and theoretical study of electron-electron and electron-phonon interactions in graphene-based compounds and topological insulators with magneto-optical spectroscopy. France-Berkeley fund: Grant ID #: 2012-0019 Supplementary information for the final report of the Stephen G. Louie Physics, University of California, Berkeley gérard Martinez CNRS-LNCMI, Université Joseph Fourier Grenoble Joint Experimental and Theoretical Study of Electron-Electron and Electron-Phonon Interactions in Graphene-Based Compounds and Topological Insulators with Magneto-Optical Spectroscopy Final Report 61 62 Figure 7: Calculated magneto-absorption spectrum for the case of spin-symmetry breaking (ferromagnetic ground state). We have shown that the n=0 Landau level of graphene is in a valley polarized ground state. We are able to explain the experimental absorption spectrum, including the emergence of a second peak above the optical phonon energy. Our work is the first optical probe of the SU(4) symmetry breaking in graphene in high magnetic fields, which has previously been studied using transport measurements only. Conclusion: The calculated spectrum is relatively insensitive to the carrier density as long as the n=0 Landau level has filling factor between 0 and 2. This explains why the two different samples show such similar spectra. We can understand this result from the symmetries of the electron-phonon interaction. The phonon couples only to the valley anti-symmetric transitions from the n=0 to the n=1 Landau level. However, light couples only to the valley symmetric transitions. In the absence of valley symmetry breaking, the phonon should not appear in the absorption spectrum. Final Report Figure 6: Calculated magneto-absorption spectrum for the case of valley-symmetry breaking. Our calculations indicate that graphene is in a valley-symmetry broken ground state in our samples. We are able to reproduce the features of the experimental data when the valley-symmetry breaking energy scale is larger than the Zeeman energy (Figure 6). On the other hand, the spectrum contains only a single peak if the system is in a spin-symmetry breaking state, that is, a ferromagnetic ground state (Figure 7). Stephen G. Louie Physics, University of California, Berkeley gérard Martinez CNRS-LNCMI, Université Joseph Fourier Grenoble Joint Experimental and Theoretical Study of Electron-Electron and Electron-Phonon Interactions in Graphene-Based Compounds and Topological Insulators with Magneto-Optical Spectroscopy France-Berkeley Fund Kunxin Luo Molecular and Cell Biology, University of California, Berkeley Delphine Javelaud Institut Curie INSERM U1021 Hippo Signaling and Ski in Human Melanoma Development Start Date: September 2012 1) Describe the work accomplished, in relation to the original project description. Melanomas are malignant tumors of the melanocytes that occur predominantly in the skin, eye and mucosa and are the most lethal form of Skin tumors, representing 75% of death from skin neoplasia. Although advances have been made in the discovery of new drugs (e.g. inhibitor of B-Raf), systematic therapies are limited, and advance melanomas respond poorly to most forms of treatment. We therefore aim to identify the molecular events that contribute to melanoma development and to improve therapeutic strategies for melanoma. The transforming growth factor β (TGFβ) pathway, signaling through the Smad proteins, has been shown to play important and complex roles in melanoma development and progression. Ski is a critical negative regulator of the Smad proteins by binding to all three Smads and repressing their transcriptional activity in the nucleus. Our previous study has shown that the ability of Ski to repress Smad signaling does not appear to be a rate-limiting step for melanoma transformation. To the contrary, downregulation of Ski by TGFβ signaling appears to be necessary for melanoma metastasis, suggesting that Ski may exert an anti-tumorigenic role in melanoma progression. In search for other Ski targets in melanoma, we recently discovered that Ski is a potent inhibitor of the YAP/TAZ proteins of the newly defined Hippo signaling pathway. The Hippo pathway plays critical roles in the control of organ size, self-renewal and expansion of stem cells and tissue-specific progenitor cells, as well as tumorigenesis. At the center of this pathway are the transcription effectors, YAP and TAZ (two highly homologous proteins that are often written as TAZ/YAP), that together with DNA binding co-factor Annual Report 2013-2014 Final Report TEAD, activate transcription of many genes that promote cell proliferation, survival, EMT and metastasis. Overexpression or activation of YAP and TAZ has been found in many malignant human cancer cells and has been shown to be critical for tumor metastasis. The goal of this proposal is to determine the role of Hippo signaling pathway in melanoma development and how its activity is modulated by crosstalk with TGFβ pathway through Ski. We will evaluate if inhibition of TAZ/YAP by Ski plays a role in limiting the metastatic potential of melanoma. We proposed to study the expression patterns and activity of Hippo signaling effector YAP/TAZ in human melanoma cell lines and tissues and whether they correlate with Ski activity/ expression. Towards this end, we have profiled Hippo pathway component expression in a panel of human melanoma cell lines and melanocytic lesions, and characterized the capacity of YAP and TAZ to control melanoma cell behavior. YAP and TAZ immuno-staining in human samples revealed mixed cytoplasmic and nuclear staining for both proteins in benign nevi and superficial spreading melanoma. TAZ was expressed at higher levels than YAP1/2 in all cell lines and in those with high invasive potential. We also proposed to study whether alteration of TAZ/YAP expression affects melanoma cell transformation, survival and migration and whether alteration of Ski expression affects these processes. We showed that stable YAP or TAZ knockdown dramatically reduced the expression of the classical Hippo target CCN2/connective-tissue growth factor (CTGF), as well as anchorage-independent growth, capacity to invade Matrigel, and ability form lung metastases in mice following tail-vein injection. YAP knockdown also reduced invasion in a model of skin reconstruct. Inversely, YAP overexpression increased melanoma cell invasiveness, associated with increased TEA domain-dependent transcription and 63 Kunxin Luo Molecular and Cell Biology, University of California, Berkeley Delphine Javelaud Final Report Institut Curie INSERM U1021 Hippo Signaling and Ski in Human Melanoma Development CCN2/CTGF expression. Together, these results demonstrate that both YAP and TAZ contribute to the invasive and metastatic capacity of melanoma cells and may represent worthy targets for therapeutic intervention. We have performed detailed mechanistic studies on how Ski regulates TAZ/YAP expression and activity in malignant breast cancer cells and showed that Ski potently inhibits TAZ/YAP activity by inducing degradation of TAZ and cytoplasmic retention of YAP. Since TAZ/YAP promotes malignant progression of melanoma, our result is consistent with our earlier model that Ski functions as a tumor suppressor in melanoma. We are in the process of reproducing the similar experiments in malignant melanoma cell lines. Finally we proposed to study the crosstalk between TGFβ signaling and YAP/TAZ in melanoma progression and whether Ski mediates this crosstalk. A previous study has reported that Hippo signaling (activated by cell-cell contact and cell density) can block TGFβ-induced cytostatic responses via sequestration of activated SMAD complexes in the cytoplasm by phospho-YAP/TAZ. We provide evidence that inhibition of TGFβ signaling by cell-cell contacts is restricted to polarized epithelial cells and independent from cytoplasmic YAP and TAZ. Rather, loss of TGFβ responsiveness in polarized cells is strictly apical, due to a strict and unique basolateral TGFβ receptor I and II distribution upon establishment of cell-cell contacts. Thus, cell type-specific inhibition of TGFβ signaling by cell density reflects polarity domain-specific TGFβ receptor localization, irrespective of Hippo pathway activation. We also examined whether TGFβ stimulation in melanoma cells could affect YAP/TAZ expression and activation via downregulation of Ski. We noticed that while TGFβ readily downregulated Ski expression in all malignant cancer cell lines, its effect on TAZ/YAP expression was not highly consistent. It turned out that TGFβ also affected the expression of SnoN, a molecule highly homologous to Ski but exerting the opposite 64 effects on TAZ/YAP signaling. The final outcome of TGFβ stimulation in various malignant cancer cell lines depends on the relative expression levels of Ski and SnoN and the strengths of their regulation of TAZ/YAP. Clearly more studies are needed to decipher the detailed mechanisms involved. In summary, the support from FBF allowed us to start a significant and productive collaborative project. We have obtained interesting results from this initial stage of study and would like to expand our collaboration through other funding mechanisms. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. UC Berkeley: • Kunxin Luo: PI, Professor; • Erwan le Scolan: postdoctoral associate; • Juliet Rashidian, postdoctoral fellow. Curie Institute: • Delphine Javelaud: Senior Scientist • Alain Mauviel: Group Leader • Flore Nallet, PhD student • Cristele Gilbert: research staff • Véronique Marsaud: research staff 3) list all publications resulting from this project. include journal titles and issues/dates. Flore Nallet-Staub, Xueqian Yin, Cristèle Gilbert, Véronique Marsaud, Saber Ben Mimoun, Delphine Javelaud, Edward B. Leof, and Alain Mauviel. Cell Density Sensing Alters TGF-beta Signaling in a Cell Type-Specific Manner, Independent from Hippo Pathway Activation. Submitted to Developmental Cell. Nallet-Staub F, Marsaud V, Li L, Gilbert C, Dodier S, Bataille V, Sudol M, Herlyn M, Mauviel A. Pro-Invasive activity of the France-Berkeley Fund Kunxin Luo Molecular and Cell Biology, University of California, Berkeley Delphine Javelaud Institut Curie INSERM U1021 Hippo Signaling and Ski in Human Melanoma Development Hippo pathway effectors YAP and TAZ in cutaneous melanoma. J Invest Dermatol. 2014 Jan;134(1):123-32. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? This is a collaborative project combining the expertise and resources of both Berkeley and French scientists. Dr. Javelaud and her colleague, Dr. Alain Mauviel, are part of the European consortium of melanoma and have access to a large collection of human melanoma cell lines and tissue samples. In addition, Dr Mauviel is among the first people to discover an interesting connection between TGFβ and Hippo signaling via Smad7 and YAP. In this project, Dr. Mauviel shared his collection of reagents and knowledge on Hippo signaling with Dr. Luo at Berkeley and helped to ensure a timely progress in the mechanistic studies. Dr. Luo at Berkeley has a strong expertise in mechanistic studies in signal transduction and especially the Ski and SnoN proteins. She has made novel discoveries on how Ski regulates YAP/TAZ signaling in cancer cells. Dr Luo has provided antibodies and other relevant reagents to Dr Javelaud to perform the immunohistochemistry Annual Report 2013-2014 Final Report studies. Both sides realize the importance of continuing collaboration on this project, and Dr. Luo is planning to apply for a sabbatical fellowship at the Institute Curie in order to expand the collaboration. We are also considering applying for a multi-PI NIH grant together. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? UC Berkeley: • Dr Kunxin Luo: Travel and lodging expense to Institute Curie: $2500 • Supplies and antibodies: $2500 Institute Curie: • Dr. Alain Mauviel: travel and lodging expense to UC Berkeley: $1500 • Molecular biology supplies: $3500 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We are very grateful to FBF for the support of our collaborative project. 65 Jitendra Malik Electrical Engineering & Computer Science, University of California, Berkeley Zaid Harchaoui & Cordelia Schmid Final Report LEAR, INRIA Large-Scale Learning for Image and Video Interpretation Start Date: January 2013 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. 1) Describe the work accomplished, in relation to the original project description. The project focused on weakly-supervised learning for human action localization from videos, object localization in images, and large-scale learning for image collection visualization. For human action localization from videos, we designed a visual descriptor that efficiently blends information from both shape (pose) and motion cues. The descriptor leverages previous works from both groups, resp. poselets descriptors from Pr. J. Malik’s group and motion-boundary histograms from Dr. C. Schmid’s group. We obtained promising experimental results with the proposed visual descriptor on several benchmark datasets for action localization in videos. For object localization from images, we proposed a twostep approach that requires minimal supervision. For each image, supervision only tells whether the object is present or not, but not where. First, we compute a submodular cover that allows to single out a set of positive object windows. Second, we use smoothed latent-SVM in order to simultaneously classify and localize the objects. The proposed approach provides a 50% relative improvement in mean average precision over the current state-of-the-art on PASCAL VOC 2007 detection. For large image collection visualization, we proposed a robust generalization of archetypal analysis, along with a fast optimization algorithm that allows to scale to web-scale image collections. Robust archetypal analysis learns a factorial representation of the data, and uncovers so-called archetypes that are sparse convex combinations of datapoints. The proposed approach yields state-of-the-art results for codebook learning, and provides intuitive and easy-to-visualize representations of huge collections of natural images. UC Berkeley: • Pr. Jitendra Malik • Pr. Trevor Darrell • Dr. Ross Girschick • Dr. Stefanie Jegelka • Georgia Gkioxari, Phd student • Hyun Oh Song, Phd student • Yuansi Chen, Phd student Inria: • Dr. Zaid Harchaoui • Dr. Cordelia Schmid • Dr. Julien Mairal • P. Weinzaepfel, Phd student 66 3) list all publications resulting from this project. include journal titles and issues/dates. “On Learning to Localize Objects with Minimal Supervision”, Hyun Oh Song, Ross Girschick, Stefanie Jegelka, Julien Mairal, Zaid Harchaoui, Trevor Darrell, ICML, 31st International Conference in Machine Learning, Jun. 2014, Beijing, China, Journal of Machine Learning Research, Conference and Workshop Proceedings. “Fast and Robust Archetypal Analysis for Representation Learning”, Yuansi Chen, Julien Mairal, Zaid Harchaoui. CVPR 2014 - IEEE Conference on Computer Vision & Pattern Recognition, Jun 2014, Columbus, United States. “Action Localization with Sequences of Movemes”, Philippe Weinzaepfel, Georgia Gkioxari, Zaid Harchaoui, Cordelia Schmid, Jitendra Malik; submitted. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationFrance-Berkeley Fund Jitendra Malik Electrical Engineering & Computer Science, University of California, Berkeley Zaid Harchaoui & Cordelia Schmid LEAR, INRIA Large-Scale Learning for Image and Video Interpretation ships between French institutions and UC campuses. Will future collaboration occur as a result of this project? For each contribution made during to the project, the work leveraged the most recent advances obtained respectively by each partner in their area expertise. For instance, for human action localization from videos, while Pr. J. Malik’s group brought its expertise in poselets learning for static images, Dr. C. Schmid’s group brought its expertise of generic dense descriptors for videos. Both technologies are blended into the “movemes” approach to get state-of-the-art performance on real-world datasets built from YouTube videos. The project fueled enduring collaboration between the two partners. Pr. J. Malik gave a course entitled “The three R‘s of computer vision: Recognition, Reconstruction, Reorganization” at the INRIA-ENS Visual Recognition and Machine Learning summer school in July 2013. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional out- Annual Report 2013-2014 Final Report side funding for this or related projects in the future, and if yes, from where? The funds allowed to foster exchanges between UC Berkeley and INRIA althroughout the project. • Pr. J. Malik visited INRIA for 3 weeks in July 2013 and gave a course entitled “The three R‘s of computer vision: Recognition, Reconstruction, Reorganization” at the INRIA-ENS Visual Recognition and Machine Learning summer school 2013 in Paris. • G. Gkioxari (PhD student, UC Berkeley) visited INRIA for 1 month in July 2013. • Z. Harchaoui visited UC Berkeley for 2 weeks in December 2013. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. The extension of the project we were granted allowed us to use the funds beyond the regular one-year expiration date. This was deeply appreciated. 67 geoffrey Marcy Astronomy, University of California, Berkeley Guillaume Hebrard Final Report Institut d’Astrophysique de Paris / Observatoire de Haute-Provence A Transatlantic Characterization of Extrasolar Planets Start Date: November 2012 1) Describe the work accomplished, in relation to the original project description. We have used the telescope at the Observatoire de HauteProvence (OHP) in France and at the Keck Observatory in Hawaii to combine Doppler measurements of several stars. The goal was to determine the orbits and masses of several planets orbiting other stars. We were successful in using the combined Doppler measurements to determine masses and orbits for two planets. We published the result in a large paper in the Astrophysical Journal. Several visits and exchanges have been made between the two teams in order to discuss and prepare observations. Some observations have already been done. Objective 1 was the study of low-mass planets around nearby stars. One target star has already been followed commonly with the American and French instruments from Mauna Kea and Observatoire de Haute-Provence. The data were combined together, and other targets identified are being observed in common. Objective 2 was on the follow-up of transiting planet candidates from Kepler. Several targets were observed with both instruments, including two object which should be published soon. Objective 3 was on the orbital tilt of long-period giant planets. One object (KOI-94) was observed with the two instruments but the SOPHIE data suffered of systematics which did not allow to be published yet, whereas the Keck data were published. Long-period transiting planets possibly observable are not easy to find; that part of the program might also target shorter-period objects. In addition, we worked on blended binary stars observed with our two instruments. These studies help to better un68 derstand these blended cases, which are a significant source of false positive detections of planets, in particular the ones in transit. We also identified a planetary system identified with Kepler and showing transit timing variations which could benefit from observations from our two instruments. In the American group, that program is led by a new Berkeley member who was not initially part of our France-Berkeley proposal. One unexpected benefit of the collaboration is that the American group traveled to Paris and to OHP to learn about the engineering of SOPHIE the novel spectrometer on the OHP telescope. The tests to stabilize SOPHIE and to use different types of fiber optics to feed SOPHIE provided valuable information for a similar spectrometer (SHREK) that the Berkeley team is hoping to build for the Keck Observatory. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • Geoffrey Marcy: Professor of Astronomy, UC Berkeley Lauren Weiss: 4th year graduate student, UC Berkeley Rebekah Dawson: Postdoctoral Fellow, UC Berkeley Guillaume Hébrard: CNRS researcher (chargé de recherche) at Institut d’astrophysique de Paris Alexandre Santerne: graduate student at Laboratoire d’Astrophysique de Marseille Claire Moutou: CNRS researcher (directeur de recherche) at Laboratoire d’Astrophysique de Marseille 3) list all publications resulting from this project. include journal titles and issues/dates. Astrophysical Journal Supplement, vol.210, Issue 2, p.20. (70 pages long). Title: Masses, Radii, and Orbits of Small Kepler Planets: the transition from gaseous to Rocky Planets. France-Berkeley Fund geoffrey Marcy Astronomy, University of California, Berkeley Guillaume Hebrard Institut d’Astrophysique de Paris / Observatoire de Haute-Provence A Transatlantic Characterization of Extrasolar Planets 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The collaboration between the two teams was very open and positive, and promising for the future. We cannot report for now a high-visibility new result that could not have been obtained without that collaboration. This is mainly due to the youth of the collaboration, whereas exoplanets programs request numerous observations on long time spans. We are optimistic that new results will be obtained in the following years thanks to that collaboration. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional out- Annual Report 2013-2014 Final Report side funding for this or related projects in the future, and if yes, from where? The award was ussed to pay visits of Berkeley members to France, and French members to Berkeley: • Lauren Weiss in France, May 2013; • Geoff Marcy in France, May 2013; • Guillaume Hébrard in Berkeley, August 2013; • Alexandre Santerne in Berkeley, Novembre 2013; • Guillaume Hébrard in Berkeley, Novembre 2013. We plan to continue exchanges between our two teams, using different sources of funding. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. Benefiting from the France-Berkeley Fund was a very good opportunity for us to start and develop collaborations between our two teams. We expect these collaborations to continue even beyond that initial support. 69 Charles Marshall Integrative Biology, University of California, Berkeley Hélène Morlon Final Report Institut de Biologie, Ecole Normale Supérieure Integrating Molecular Phylogenies and the Fossil Record Start Date: October 2012 1) Describe the work accomplished, in relation to the original project description. As proposed in our application, we organized and ran a workshop at UC Berkeley. This workshop took place on September 23rd-25th. The workshop was a success, generating really good discussions between neontologists and paleobiologists, theoreticians and empiricists. Participants found the workshop very stimulating, as illustrated by this post from Tracy Heath (UC Berkeley) who participated in the workshop (http://treethinkers.org/workshop-on-integratingmolecularphylogenies-and-the-fossil-record/). There were about 20 participants (including graduate students, postdocs, research scientists, and professors) for the whole three days—a good number of people for an exciting discussion, but not so large as to prevent people from participating. The workshop began with a symposium of talks (listed below) by 12 researchers from Europe and North America. Reading the talk titles, it’s hard to ignore the importance of activities like this. Much of the work presented had significant overlap, so this was a great opportunity to establish new collaborations. As theoreticians, it’s easy to work on a project without knowing that someone else (many time zones away or even in the same institution) is working on something similar or an idea that could nicely fit into some unified framework. This really underscores the importance of efforts like this workshop. The following day, we all got together in the morning and started brainstorming about important directions in the field of macroevolution. This was a thoroughly enjoyable discussion that culminated in an outline of important questions in macroevolution and how fossil information can help to answer them. We then formed small, break-out groups on four important topics: (1) diversity dynamics, (2) phenotypic evolution, (3) adaptive radiations and (4) bioge70 ography. The break-out groups developed these ideas for the rest of the workshop, discussing methodological, conceptual, and data shortfalls. Following the workshop, several groups of researchers have pursued research initiated or discussed at the workshop, as detailed in the list of publications in (3) and the ongoing collaborations in (4). FBF Fossils & Phylogenies Symposium • Sam Price & Lars Schmitz — Report from the NESCent catalysis meeting: Successes and areas requiring further effort • Charles Marshall — Some observations of the value of the fossil record in quantifying diversity dynamics, and the need for improvement in the use of fossils in calibrating molecular phylogenies • Michael Alfaro — Challenges to integrating fossils and molecular data • Daniele Silvestro — Estimation of macroevolutionary rates from fossil occurrence data • Todd Parsons — Estimating long term diversity dynamics using molecular phylogenies and limited fossil record • Tracy Heath — The fossilized birth-death process: A coherent model of fossil calibration for divergence time estimation • Gilles Didier — Integrating the fossil record in speciation and extinction rates estimations • Nick Matzke — Statistical model choice for old and new biogeographical cladogenesis models: Comparing DEC, DIVA, BayArea, and measuring the importance of founder-event speciation, with and without models for imperfect detection of fossils • Thomas Ezard — The meaning of birth and death in macroevolutionary birth-death models, and its consequences for models of molecular evolution • Hervé Sauquet — Proteaceae diversification through time France-Berkeley Fund Charles Marshall Integrative Biology, University of California, Berkeley Hélène Morlon Institut de Biologie, Ecole Normale Supérieure Integrating Molecular Phylogenies and the Fossil Record • • Joshua Schraiber — Dating the great ape phylogeny using phylogenomics and fossil tip dating Chelsea Specht — To be or not to be (resolved): Incorporating fossils in phylogenies of Zingiberales 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • • • • • • • • • • • • Michael Alfaro – associate professor Lucy Chang – doctoral student Gilles Didier – assistant professor Thomas Ezard – NERC advanced fellow Gustavo Burin Ferreira – doctoral student Tracy Heath – postdoctoral researcher Jenna Judge – doctoral student Jun Ying Lim – doctoral student Susana Magallon - professor Charles Marshall - professor Nick Matzke – postdoctoral researcher Hélène Morlon – CNRS researcher Todd Parsons – CNRS researcher Hervé Sauquet - assistant professor Joshua Schraiber – doctoral student Daniele Silvestro – postdoctoral researcher Chelsea Specht – associate professor Susan Tremblay – doctoral student 3) list all publications resulting from this project. include journal titles and issues/dates. The publications below highly benefited from discussions we had at the workshop supported by the FBF. Already published: Heath, T. A., Huelsenbeck, J. P., & Stadler, T. (2014) The fossilized birth–death process for coherent calibration of diver- Annual Report 2013-2014 Final Report gence-time estimates. Proceedings of the National Academy of Sciences, 201319091 Moen, D. S. & Morlon, H. (2014) From dinosaurs to modern bird diversity: Extending the time scale of adaptive radiation. PloS Biology 12:e1001854 Morlon, H. (2014) Phylogenetic approaches for studying diversification. Ecology Letters 17: 508-525 Silvestro, D., Schnitzler, J., Liow, L. H., Antonelli, A. & Salamin, N. (2014) Bayesian estimation of speciation and extinction from incomplete fossil occurrence data. Systematic Biology 63 (3), 349-367 In preparation: Condamine, F. L., Nagalingum, N. S., Marshall, C. R. & Morlon, H. Branching process prior influences Bayesian molecular dating: an empirical assessment with cycads (Cycadales) 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? All the participants were really involved in the workshop. The workshop strengthened already existing relationships or initiated new relationships between (on the French side) Gilles Didier (Institut de Mathématiques de Luminy), Hélène Morlon (Ecole Normale Supérieure), Todd Parsons (Université Pierre et Marie Curie & Collège de France) and Hervé Sauquet (Université Paris Sud) and (on the UC side) Michael Alfaro (UCLA), Lucy Chang (UCB), Tracy Heath (UCB), Jenna Judge (UCB), Jun Ying Lim (UCB), Charles Marshall (UCB), Nick Matzke (UCB), Joshua Schraiber (UCB), Chelsea Specht (UCB) and Susan Tremblay (UCB). 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional out71 Charles Marshall Integrative Biology, University of California, Berkeley Hélène Morlon Final Report Institut de Biologie, Ecole Normale Supérieure Integrating Molecular Phylogenies and the Fossil Record side funding for this or related projects in the future, and if yes, from where? There are ongoing collaborations resulting from this project, including ongoing collaborations between: Charles Marshall and Hélène Morlon on cycads diversification, Susana Magallon and Hélène Morlon on age-richness relationships, Michael Alfaro and Tiago Quental on detecting diversity declines, Thomas Ezard and Tiago Quental on diversity-dependence in phylogenies and fossils, Daniele Silvestro and Tiago Quental on canids diversification. All the money (+external money from participants’ own grants) was spent in running the workshop held at Berkeley. Exciting ideas and new collaborations stemming out of the project have generated (and will continue to generate) solicitations for additional outside funding from participants. For example, Tiago Quental and Thomas Ezard (who met at the workshop in Berkeley) have obtained funding to hold a UoS/ FAPESP biodiversity regulators workshop on a related project 72 that will lead to a theme issue in Philosophical Transactions of the Royal Society–B including contributions from participants of the workshop (e.g. Hélène Morlon, Charles Marshall). Samantha Price and Lars Schmidt have also obtained funding from NESCent to held a course that will teach participants to use fossil and phylogenetic data to analyze macroevolutionary patterns using traditional paleobiological stratigraphic methods, phylogenetic comparative methods and combined fossil and tree approaches. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. This was overall a very good experience. However it was challenging to invite enough particiants to achieve a critical mass with the allocated funds; many participants had to contribute their own money to attend the workshop, which limited the participation of young French researchers. France-Berkeley Fund Stephanie L. Mudge Sociology, University of California, Davis Antoine Vauchez CNRS, Université Paris I – Sorbonne When Theory Matters: Law, Economics, and the Scholarly Production of “Europe,” 1990-2010 Start Date: January 2013 1) Describe the work accomplished, in relation to the original project description. 1. Data collection, still ongoing, was undertaken at the archives of the European Union in Florence in September 2013 and at the European Commission (Brussels) in the spring of 2014. This spent down our remaining FBF funds to zero. Matching grants from UC-Davis sources still remain, which will be used in Fall 2014 for a follow-up research trip by A. Vauchez to Frankfurt in Fall/Winter 2014. 2. An initial working session was held at the Université Paris 1-Sorbonne in late February-early March 2013. The principal investigators collected information, drew up research plans, and made a preliminary production schedule for a new working paper. We also made arrangements for the spring workshop. 3. In April 2013, we held our main event, a workshop of all project participants, in Berkeley. The workshop program was provided with our interim report. 4. Our group has expanded to include a graduate student from UC-Davis (Ezekiel Baker, Sociology) and has successfully applied to hold an SSHA conference panel in November 2014. The panel will serve as a final discussion forum for papers first discussed in Berkeley, for purposes of finalizing a special issue for journal submission. In the meantime, the co-PIs of the project are assembling a special issue proposal for the British Journal of Sociology. 5. The co-PIs are also authoring an additional paper based on our research for a special issue of the Sociological Review, edited by Julian Go and Monika Krause. Annual Report 2013-2014 Final Report 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • Stephanie L Mudge – Assistant Professor, Sociology, UC-Davis Sociology Antoine Vauchez – Research Professor, CNRS Ezekiel Baker – Doctoral Student, Sociology, UC Davis Antonin Cohen – Professor, Université Paris Ouest Nanterre La Défense Frédéric Lebaron – Professor, Sociology, Université de Versailles-Saint-Quentin-en-Yvelines. Lisa Stampnitzky – Lecturer, Harvard University 3) list all publications resulting from this project. include journal titles and issues/dates. Publications are in preparation (see items 4 and 5, under question #1, above). 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The project has brought together American and French scholars who share an interest in the use of Bourdieusian field theory to analyze Europe and other transnational social phenomena, who otherwise may not have had a chance to collaborate. This core group is now a basis for the construction of a broader, bi-continental research network, including graduate students, and thus a potentially important professional resource and basis of ongoing collaborative research. As evidence of new collaborative possibilities, most of the FBF project participants also submitted an important joint research project application to the French Agence Nationale de la Recherche with a proposed budget of about 150,000 euros. Our initial application was unsuccessful, but we will resubmit our proposal and will use it to seek other funding 73 Stephanie L. Mudge Sociology, University of California, Davis Antoine Vauchez Final Report CNRS, Université Paris I – Sorbonne When Theory Matters: Law, Economics, and the Scholarly Production of “Europe,” 1990-2010 sources. We have also used our collaboration as a means of drawing in new graduate students (in particular, Zeke Baker, UC-Davis) and for planning new research (for example, the new paper to be co-authored by the PIs, Vauchez and Mudge, for the Sociological Review, mentioned above). 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We greatly appreciated FBF support, and in particular the Fund’s flexibility in working with us as our work developed. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Total project budget: $11,500 ($4,000 from FBF) Spent to-date: $8,923 total (100% of FBF funds were spent), as follows: 1) Research meeting in Paris: $700 2) Workshop in Berkeley : $7050 3) Data collection and research assistance/transcription: $1173 [1 of 2 research trips completed, due to logistical reasons.*] (which do not have a deadline, and which were not spent for logistical reasons having to do with A. Vauchez’s location in the US during 2013-2014) by December 2014. 74 France-Berkeley Fund Véronique Munoz-Dardé Philosophy, University of California, Berkeley Luc Foisneau Etudes Politiques, EHESS A Theory of Justice Forty Years On Start Date: December 2012 1) Describe the work accomplished, in relation to the original project description. The project is a one-year project financed by the France-Berkeley Fund. The research focuses on the origins in contractualist theory, and on the nature and transformations of Rawls’s A THEORY OF JUSTICE during the 40 years that have elapsed since its publication in 1971. In the first half of 2013, Luc Foisneau (LF)’s seminar at the EHESS focused on A Theory of Justice and the question of obedience to the rule. Véronique Munoz-Dardé (VMD)’s seminar at Berkeley focused on a close reading of A Theory of Justice 40 years on. In February of 2013, VMD gave a talk in LF’s seminar at the EHESS on Raz, Rawls and the question of obedience. In June of 2013, we organized a conference in Paris with the participation of two Berkeley doctoral students, Alex Kerr and Erin Beeghly, a colleague from Berkeley, Michael Martin, and 4 French colleagues (Emmanuel Picavet – Paris 1; Christopher Hamel – Université Libre de Bruxelles; Bernard Manin – EHESS; Charles Girard – Paris 4). Luc Foisneau and Véronique Munoz-Dardé have also given contributions, one on ‘Discrimination of gender and race in Rawls’, the other on Rawls and Hume (in coll. with Michael Martin). The theme of the conference was: ‘A Theory of Justice Forty Years On: From theory to practice?’ The general idea was to confront some of the main theoretical themes of A Theory of Justice with practical concerns such as handicap, education, stereotyping, incentives, race and gender. The date of the conference fitted well into the original projected timeline. In 2013-14, LF’s seminar at the EHESS focused on theories of justice and environment, and VMD’s seminar was on themes in contractualism: authority, aggregation and pluralism. Annual Report 2013-2014 Final Report In December of 2013, we organized two workshops in Berkeley with the participation of the two directors, colleagues in the Department of Philosophy and the Department of Political Science, a post-doctoral Fellow from EHESS, Dr Luciano Venezia, and several doctoral students at Berkeley working on issues related to contractualism and anti-contractualism, old and new. At the first workshop, Luciano Venezia and Luc Foisneau presented their work on authority in Raz and Rawls. At the second workshop, organized by Professor Kinch Hoekstra (Political Science and Law), Venezia presented a historical communication on Hobbes and contractualism and Foisneau presented a historical communication on Hobbes and majority rule. The two project-directors have also written a book together for Les Editions de l’EHESS, in the series Audiographie. The title of the book published in 2014: John Rawls, Justice et critique. 75 Véronique Munoz-Dardé Philosophy, University of California, Berkeley Luc Foisneau Final Report Etudes Politiques, EHESS A Theory of Justice Forty Years On 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. Professors: • Luc Foisneau (Programme Director) • Véronique Munoz-Dardé (Programme Director) • Michael Martin (Berkeley and UCL) • Bernard Manin (EHESS and Chicago) • Emmanuel Picavet (Paris 1) • Céline Spector (Bordeaux 3) Associate Professors : • Kinch Hoekstra (Berkeley) • Charles Girard (Paris 4) • Feriel Kandil (Aix-Marseille) Post-Doctoral Fellows: • Christopher Hamel (Université Libre de Bruxelles) • Luciano Venezia (EHESS/CONICET) Doctoral students : • Erin Beeghly (Berkeley, now Assistant Professor at the University of Utah) • Alex Kerr (Berkeley) • Nick Gooding (Berkeley) • Julian Jonker (Berkeley) • Michael Diaz (Berkeley) • Francesca Rebasti (EHESS) • Ophélie Desmons (Lille, now post-doctoral fellow at Lille) 3) list all publications resulting from this project. include journal titles and issues/dates. Book Translation and commentary by Luc Foisneau and Véronique Munoz-Dardé Rawls, John: Justice et Critique, Editions de l’EHESS, collection Audiographie, February 2014, ISBN 76 978-2-7132-2411-9 (Review: http://www.nonfiction.fr/ article-6958-la_philosophie_comme_discipline_conversationnelle.htm) Articles Luc Foisneau, « Rawls et la justification de la règle de majorité ». Raisons politiques. Revue de théorie politique. N° 53, Feb. 2014, pp. 63-79. Luc Foisneau, « La démocratie à rebours. Hobbes et la règle de majorité ». Le Philosophoire. Laboratoire de philosophie. N° 39, 2013, pp. 147-162. Véronique Munoz-Dardé, « In the Face of Austerity: The Puzzle of Museums and Universities ». Journal of Political Philosophy, Volume 21, Number 2, 2013, pp. 221–242. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The project has resulted in many fruitful exchanges and publications (see above). Some of the doctoral students at Berkeley, among them Nick Gooding who participated in both of the Fall workshops at Berkeley, will seek funding to work for a term at the EHESS with Luc Foisneau on historical aspects of the contractualist tradition. Luciano Venezia will seek funding to work for a few weeks at Berkeley. Building on the success of the project, the two directors plan to submit in the next couple of years a more ambitious cooperative project. France-Berkeley Fund Véronique Munoz-Dardé Philosophy, University of California, Berkeley Luc Foisneau Etudes Politiques, EHESS A Theory of Justice Forty Years On 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? France Berkeley Fund Budget Fund #40659 Grant Amount: $10,000.00 France Conference $4,600.00 Alex Kerr Stipend for Airfare, Hotel and Catering Projected and actual: $2,400.00 Erin Beeghly Stipend for Airfare Hotel and Catering Projected and actual: $2,200.00 Catering: Conference in Paris Projected: $800.00, actual: Final Report As stated above, we may ask for funding for a more ambitious cooperative project, but are still in the process of drafting it. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. Although the amount of money given for each project is modest, we felt that it gave us the opportunity for involving doctoral students and colleagues at each of our institutions in meaningful research. It helped very much that we were able to communicate with very efficient administrators who advised us in the process of drafting our research project and who were extremely supportive at every stage. $0 Berkeley Conference $5,420.16 Luc Foisneau RT Airfare Paris/Berkeley Projected $1,200.00, actual $1,067.70 Luciano RT Airfare Paris/Berkeley Projected $1,200.00, actual $1,033.00 Limo RT for two people SFO/Berkeley Projected and actual: $300.00 Hotel Women Faculty Club 5 nights for 2 people Berkeley Projected $1,500.00, actual $ 1,357.50 Meals 5 days for two people Berkeley Projected $500.00, actual $572.48 Catering Workshop in Berkeley Projected $600.00, actual $725.59 Hotel for Luciano Venezia Nov 30, Dec 1 Actual: $363.90 tOtAl (ACtUAl): $10,020.16 Annual Report 2013-2014 77 Vern Paxson Electrical Engineering & Computer Sciences, University of California, Berkeley Renata Cruz Teixeira Final Report LIP6, Université Marie et Pierre Curie Understanding User Perspectives of Internet Performance Start Date: October 2012 1) Describe the work accomplished, in relation to the original project description. Over the course of the FBF funding period, we made substantial progress on our collaborative effort to build a home network troubleshooting service, which combines the two research goals we outlined in the original proposal. The project aimed to leverage the presence of multiple devices in the home in order to identify problems stemming from individual devices, their location in the home, and potential deficiencies in the uplink connecting the home to the Internet. We were able to broaden our collaboration to also include members of the BISmark project at Georgia Tech (not funded via this grant), which allowed us to include the gateway device in the analysis process—a key benefit due to the gateway’s strategic location between home network and Internet backbone. The system has reached the stage of a working prototype that we refine continuously. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • Mohan Dhawan (Doctoral student) Anna-Kaisa Pietilainen (Post-doc) Sarthak Grover (Doctoral student) Stephane Archer (Undergrad intern) Christian Kreibich (Researcher) Vern Paxson (Professor) Renata Teixeira (Researcher) 3) list all publications resulting from this project. include journal titles and issues/dates. “Fathom: A Browser-based Network Measurement Platform”, M. Dhawan, J. Samuel, R. Teixeira, C. Kreibich, M. Allman, 78 N. Weaver, and V. Paxson, ACM Internet Measurement Conference, 2012, Boston, USA. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The project grew out of a fledgling collaboration between our research teams at UC Berkeley and UPMC in Paris. The FBF award allowed us to cement this partnership, including introducing new project personnel both in France (Anna Pietilainen, one of Dr. Teixeira’s post-docs) and at a new partnering site (Sarthak Grover, a Ph.D. student in Prof. Nick Feamster’s group at Georgia Tech, currently visiting Dr. Teixeira in Paris). We are quite confident these relationships will extend considerably into the future, given we have found an effective way to work together and produce strong results. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? The funds supported four trips facilitating the collaboration. Two of these were for one of the doctoral student, enabling him to engage in an extensive visit at Paris, as well as to attend the ACM Internet Measurement Conference to present results derived from the collaboration. The other two trips enabled Berkeley researchers to to spend time at LIP6 and associated labs, which significantly accelerated the progress of the collaboration. Regarding additional outside funding, we have already obtained a gift from Google to pursue our research on home network troubleshooting from the browser. We also plan to apply for funding from Comcast. France-Berkeley Fund Vern Paxson Electrical Engineering & Computer Sciences, University of California, Berkeley Renata Cruz Teixeira LIP6, Université Marie et Pierre Curie Understanding User Perspectives of Internet Performance 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We have found the FBF funds highly helpful in developing momentum for our collaboration, and much appreciate the Annual Report 2013-2014 Final Report opportunities this provided. We appreciated the streamlined nature of the proposal and grant process, and would readily recommend the program to colleagues. 79 Kenneth Ribet Mathematics, University of California, Berkeley Ariane Mézard Final Report Institut de Mathématiques de Jussieu, Université Pierre et Marie Curie Summer Graduate School: New Geometric Techniques in Number Theory Start Date: July 2013 1) Describe the work accomplished, in relation to the original project description. Le financement France-Berkeley Ribet-Mézard a été utilisé, comme prévu, pour permettre l’organisation de l’école d’été “New Geometric Techniques in Number Theory” au MSRI, Berkeley du 1 juillet au 12 juillet 2013. Impact à court terme Ce financement additionnel au budget initialement dédié par le MSRI pour cet école a permis une ouverture internationale exceptionnelle pour les intervenants. Le MSRI a pris en charge quatre autres intervenants européens (T. Gee, P. Scholze, T. Richarz, G. Boxer). L’attractivité de l’école d’été n’en a été que décuplée. Réunir ces spécialistes reconnus (mais rarement simultanément présents sur le sol américain) dans le cadre d’une formation doctorale accélérée dans un sujet en pleine expansion a permis d’attirer une population extrêmement brillante de doctorants américains. L’ambiance était très studieuse avec un souci permanent de profiter au mieux des exposés proposés. Il a notamment été impossible 80 de mettre en parallèle plusieurs sessions simultanées, les étudiants souhaitant absolument pouvoir assister à tous les exposés. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. Six personnes (trois français de l’Université Pierre et Marie Curie, et de l’Ecole Normale de Lyon, trois américains de l’université de Californie, Berkeley) ont bénéficié de ces fonds: Deux professeurs • Ariane Mézard • David Nadler Trois assistants • Gabriel Dospinescu • Penghui Li • Daniel Appel Et un doctorant • Pierre Jalinière C’est donc la moitié des effectifs des enseignants de cette école d’été qui a été pris en charge par le fond France-Berkeley. France-Berkeley Fund Kenneth Ribet Mathematics, University of California, Berkeley Ariane Mézard Institut de Mathématiques de Jussieu, Université Pierre et Marie Curie Summer Graduate School: New Geometric Techniques in Number Theory 3) list all publications resulting from this project. include journal titles and issues/dates. n/a Final Report 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? Les futurs post-doctorants américains, participants de cette école d’été, ont pris conscience qu’une année de post-doctorat en Europe et plus particulièrement en France serait une ouverture extrêmement favorable dans le cadre de leur évolution scientifique. Enfin, à l’échelle individuelle des porteurs du projet, A. Mézard a eu l’opportunité de rencontrer K. Ribet et A. Ogus (head of mathematics department UC Berkeley) pour discuter des conditions scientifiques et matérielles de son séjour longue durée au département de Mathématiques de l’UC Berkeley (jan-juin 2015). Le financement France-Berkeley a dont été initiateur d’un projet de collaboration à beaucoup plus long terme entre les deux partenaires. New Geometric Methods in Number Theory and Automorphic forms Organizers: Pierre Colmez (L’Institut de Mathématiques de Jussieu), Wee Gan (National University of Singapore), LEAD Michael Harris (L’Institut de Mathématiques de Jussieu), Elena Mantovan (California Institute of Technology), Ariane Mezard (Institut de Mathématiques de Jussieu), Akshay Venkatesh (Stanford University) Geometric Representations Theory Ngo Bao Chau (University of Illinois), LEAD David Ben-Zvi (University of Texas), Thomas Haines (University of Maryland), Florian Herzig (University of Toronto), Kevin McGerty (University of Oxford), David Nadler (University of California, Berkeley), Catharina Stroppel (Hausdorff Research Institute for Mathematics, University of Bonn), Eva Viehmann (Hausdorff Research Institute for Mathematics, University of Bonn) Par ailleurs, Ariane Mézard a obtenu un financement pour un séjour longue durée (janvier- juin 2015) à l’UCB pour développer ses travaux de recherche en collaboration avec Kenneth Ribet, Sug Woo Shin et leurs doctorants dans le cadre du programme Fulbright Visiting Scholar. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Le financement France-Berkeley a été utilisé pour permettre l’organisation de l’école d’été du 1 juillet au 12 juillet 2013. L’un des premiers objectifs atteints de ces écoles d’été était d’inciter la participation des futurs post-doctorants aux semestres MSRI aout-dec 2014 et d’en préparer l’organisation concrète en permettant à deux organisateurs (A. Mézard et D. Nadler) de rencontrer les responsables du MSRI. Ces conférences (aout-décembre 2014) seront financées par le MSRI. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. L’impact de ce financement a été très fort : ce séjour à Berkeley a accru considérablement la visibilité internationale de A Mézard et a marqué le début d’une internationalisation de sa carrière. Elle est à présent activement sollicitée pour des invitations de longue ou moyennne durée hors Europe (Japon, Etats-Unis, Inde...). Ce sont, à chaque fois, des opportunités pour diffusersmes résultats, démultiplier les échanges et mettre en place des collaborations fructueuses. Ma seule recommandation : faire perdurer ce programme utile souple et efficace. Annual Report 2013-2014 81 Michael A. Rogawski Neurology, University of California, Davis Jean-Pierre Mothet Final Report CRN2M UMR7286 CNRS, Aix-Marseille Université Role of D-Serine in Migraine Start Date: 2012 • 1) Describe the work accomplished, in relation to the original project description. The main objective of our project was to determine the contribution of the neuromodulator D-serine to cortical spreading depression (CSD), which represents a critical physiological event in migraine. We hypothesized that an understanding of the role of D-serine in CSD would enable the development of improved treatments for migraine. The project combines in vivo electrophysiological recording together with amperometric detection of D-serine. A critical element in the project is the establishment of a colony at UC Davis Mouse Biology Program animal facility of a strain of genetically engineered mice (serine racemase knock-out mice). This colony was established and regularly produces mice for experiments. In addition, the two teams learned how to conduct surgeries in mice to introduce canulae and headmounts for joint biosensing and EEG recording. The surgical procedures were new and required considerable joint experimentation. In addition, the teams worked together to prepare and calibrate a D-serine biosensor system that is now operational. Experiments with wild type and the serine racemase knock-out mice are planned. • 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • Michael A. Rogawski, M.D., Ph.D., Professor, Department of Neurology, School of Medicine and Center for Neuroscience, UC Davis Jean-Pierre Mothet, Ph.D. Group Leader, Aix-Marseille Université and Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille, CNRS Matilde Le Bail, doctoral student, Aix-Marseille Université 82 • Dorota Zolkowska, M.D., Ph.D., Assistant Project Scientist, UC Davis Christoph Lossin, Ph.D., Professional Researcher, UC Davis Lisa Olsen, Research Assistant, UC Davis 3) list all publications resulting from this project. include journal titles and issues/dates. None to date. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The grant from the France-Berkeley Fund allowed the French and American teams to work together to jointly tackle a difficult problem. The Mothet team brought expertise in the neurobiology of D-serine and on the manufacture of D-serine biosensors. The Rogawski team contributed expertise in migraine research and murine models, including skills in the surgical implantation of chronic recording electrodes in mice. Although Rogawski and Mothet have long sought to work together on a collaborative project, this was not possible because of the geographic barrier separating their two laboratories. No other source of funding was available to bring the research teams together. The long held desire was transformed into reality by the funding received from the France-Berkeley Fund. Having Mothet and his student Mathilde Le Bail visit UC Davis allowed the transfer of specific knowledge and skills on D-serine and the use of the biosensor. In addition, the visit strengthened the ties between the laboratories. Given the close affiliation generated by the visit supported by the France-Berkeley Fund, it is anticipated that the collaboration will continue. France-Berkeley Fund Michael A. Rogawski Neurology, University of California, Davis Jean-Pierre Mothet CRN2M UMR7286 CNRS, Aix-Marseille Université Role of D-Serine in Migraine 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Funds were spent on flight tickets for Matilde Le Bail and Jean-Pierre Mothet to travel from France to Sacramento and for 3 months housing. Additional funds were used to purchase equipment items and animals. The funds from the France-Berkeley Fund were substantially supplemented by general research funding available to Rogawski, which were applied to the collaborative project. The teams intend to apply for joint research funding in the future. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. We are extremely grateful to the Fund for providing support that enabled us to initiate our collaboration. Working to- Annual Report 2013-2014 Final Report gether, the French and American principal investigators were able to jointly chart the course of the project and to share knowledge and technical skills. A student from the French team and several scientists from the American team were able to work together at the lab bench to develop novel experimental methodologies. However, to fully realize the research opportunity, a more sustained effort is required. One way to maintain project momentum would be for the French student to remain in the American lab for a more extended period of time, for example with the support of an international student exchange fellowship. Assistance in obtaining such a fellowship would be greatly appreciated. We believe that such a student fellowship would allow full realization of the seed investment provided by France-Berkeley Fund. 83 Jeffrey Ross-ibarra Plant Sciences, University of California, Davis Maud Tenaillon Final Report Plant Genetics, CNRS, UMR de Génétique Végétale Does Domestication Affect Recombination: A Pilot Study in Maize Start Date: XXX 2012 1) Describe the work accomplished, in relation to the original project description. In total, we have genotype data from 700 teosinte progenies of 20 mothers. We then spent ~6 months developing statistical genetic methods to 1) identify maternal and paternal plants for each genotype 2) phase the parents using genotype data from the progeny and 3) phase and impute genotypes of the progeny using phased data from parental plants. Our simulations show these methods work with very high accuracy (>95%), and we are currently finishing applying them to the genotype data. These data will then be shared with Falque and Tenaillon groups, and they will estimate recombination rates. Data from the associated mapping project will provide genotypes for a similar number of maize plants. 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • Jeffrey Ross-Ibarra (Associate Professor, UC Davis) Maud Tenaillon (CNRS Researcher) Mathieu Falque (INRA Researcher, UMR de Génétique Végétale) Vincent Buffalo (former staff scientist, current graduate student, UC Davis) 3) list all publications resulting from this project. include journal titles and issues/dates. None to date, at least two planned. The first will be on estimating recombination rate from progeny arrays and variation in maize landraces. The second will be on comparison between maize and teosinte. 84 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The Ross-Ibarra lab has developed statistical tools to take advantage of future large multiparent mapping populations to identify parents and phase and impute genotypes of both parents and offsprings. The Tenaillon and Falque groups at UMR will utilize these data to estimate recombination rates in maize and teosinte and compare across populations and families. We are hopeful that this collaboration will continue to prove fruitful as we investigate other aspects of our mapping populations, as it will allow us to answer questions about correlations of inbreeding depression and linked selection with patterns of recombination. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? Funds were spent to covering genotyping by sequencing. Initially we had plans to genotype crosses performed at UC Davis and UMR, but neither set of crosses produced sufficient seeds. Instead, we used the funds to genotype additional individuals from a mapping population of maize and teosinte that was underway from a related project. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. This was a great opportunity to generate pilot data and work out methods of dealing with reduced representation sequencing to identify recombination rates. The difficulties were on our end with getting successfull crosses! France-Berkeley Fund John W. Taylor Plant and Microbial Biology, University of California, Berkeley tatiana giraud Department Genetique et Ecologie Evolutive, Université de Paris-Sud Fungal Ecological Genomics Start Date: September 2012 1) Describe the work accomplished, in relation to the original project description. The research that we proposed could not be supported by the FBF grant alone, but FBF support was essential to realizing the goals of the ambitious research project by funding travel and enabling the first two international meetings in the new field of fungal population genomics. To accomplish all of the research goals, we were fortunate to have funds from a Marie Curie Outgoing Fellowship (MCOF) to provide support for Dr. Pierre Gladieux and laboratory funds to supplement the MCOF grant from Prof. J. Taylor. Central to the proposed research was the combined expertise of Dr. Tatiana Giraud and her group in Paris and Prof. J. Taylor and his group in Berkeley. Although the MCOF program is based on collaboration between the Giraud and Taylor labs, the MCOF provided no funds for travel to facilitate scientific exchange. Therefore, we aimed to leverage the FBF funds to greatly enhance the investment by the MCOF and Taylor’s lab by funding two meetings, one for Gladieux and Taylor and a young postdoc to travel to Giraud’s lab and one for Giraud and a young postdoc to travel to Taylor’s lab. The purpose of the meetings was to educate all the members of both labs, and to enhance both the critical evaluation of research in progress and the planning of future research — tasks best accomplished by physical meetings between researchers in the labs of the FBF principal investigators, and in neighboring labs. As for the lab-work part of the project, we greatly exceeded expectations by obtaining genome sequences of 130 individuals of one Neurospora species, Neurospora discrete 4b, eclipsing our work on N. crassa by ca. 80 genomes. We are currently writing a publication based on the analyses of a first batch of genomic sequences of 50 Neurospora discreta 4b individuals. We are also finishing up lab experiments (in vitro Annual Report 2013-2014 Final Report crosses between fungal individuals) and analyzing a second batch of another 80 individual genomes. Both data sets will form the basis of publications. The France-Berkeley-Fund support has been, in our experience, unexpectedly successful in fostering relationships between Berkeley and France: • T. Giraud and postdoc Jeanne Ropars visited the Taylor lab in Berkeley in March 2013 • Ms Fanny Perraudeau, from the Ecole Polytechnique in Palaiseau, joined the Taylor lab for four months in 2013 and participated in data analysis under Gladieux and Taylor’s supervision. This experience instilled a taste for research in Ms Perraudau, who is now embarking on a PhD in Biostatistics at UC Berkeley. Her work is being incorporated into the research paper we are currently writing. • J. Taylor, T. Giraud and P. Gladieux organized the first ever Fungal Population Genomics workshop. It was held in March 2013 in Berkeley to take advantage of researchers coming to California for the Fungal Genetics Conference. We attracted 30 leading researchers from nine institutions (UC Berkeley, U Paris-Sud, Duke U, UC Riverside, Shanghai Inst, ETH Zurich, Wageningen U, Uppsala U, Nottingham U, MPI Marburg) including five from the FBF group, PI Taylor, postdoc Pierre Gladieux and graduate student Emily Whiston from Berkeley and PI Giraud and postdoc J Ropars from U Paris-Sud, Orsay, three of whom presented research (Gladieux, Whiston and Giraud). At this time, we also had the FBF meeting between Berkeley and U Paris-Sud researchers. • In April 2013, PI Taylor visited PI Giraud’s lab at the U Paris-Sud to make a presentation on the most recent Neurospora crassa research, a visit that was not charged to the FBF grant. 85 John W. Taylor Plant and Microbial Biology, University of California, Berkeley tatiana giraud Final Report • • Department Genetique et Ecologie Evolutive, Université de Paris-Sud Fungal Ecological Genomics J. Taylor and postdocs visited the Giraud lab for a week in Orsay in April 2014 to hold the FBF meeting. The Giraud lab was also hosting PI Hanna Johannesson and her students and postdocs at this time, making for an excellent opportunity for discussions and collaborations on fungal mating type chromosomes and Neurospora population genomics. In April 2014, J. Taylor, T. Giraud and P. Gladieux organized the second Fungal Population Genomics workshop, this time held in Orsay. We attracted 15 young and experience researchers from (UC Berkeley, U ParisSud, Uppsala U, ETH Zurich, MPI Marburg, INRA Nancy, Harvard U) including : PI Taylor, postdocs Gladieux and Sara Branco from Berkeley, and graduate students Alice Feurtey and Hélène Badouin, postdocs J Ropars, Ricardo Rodriguez de la Vega, junior Assistant Professor Antoine Branca, and PI Giraud from U Paris Sud. All presented research except the two PIs and A. Feurtey who has very recently joined the Giraud lab. This meeting brought a large attendance of fungal evolutionary biologists and ecologists from various institutes of the Paris Metropolitan Area and even further (INRA Versailles/ Grignon, Museum National d’Histoire Naturelle, U Paul Sabatier, Toulouse). 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • • • • • • PI John Taylor, Professor UC Berkeley PI Tatiana Giraud, CNRS Researcher Pierre Gladieux, Postdoc UC Berkeley Sara Branco, Postdoc UC Berkeley Emily Whiston, PhD Student UC Berkeley Iman Sylvain, PhD Student UC Berkeley Monika Fischer, PhD Student UC Berkeley Christopher Hann-Soden, PhD Student UC Berkeley 86 • • • • • Alice Feurtey, PhD Student U Paris Sud Hélène Badouin, PhD Student U Paris Sud Jeanne Ropars, Postdoc U Paris Sud Ricardo Rodriguez de la Vega, Postdoc U Paris Sud Antoine Branca, Maitre de Conférence U Paris Sud 3) list all publications resulting from this project. include journal titles and issues/dates. Gladieux P, Ropars R, Badouin H, Branca A, Aguileta G, de Vienne DM, Rodriguez de la Vega R, Branco S, Giraud T. (2014) Fungal evolutionary genomics provide insights into the mechanisms of adaptive divergence in eukaryotes. Molecular Ecology 23(4):753:773 Gladieux et al. Population genomics of Neurospora discreta: Structure and differentiation. Ms in preparation. Gladieux et al. Population genomics of Neurospora discrete: Gene flow and migration. Ms in preparation. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? The collaboration was totally new. Although Pis Giraud and Taylor had met several times at meetings, and each had collaborated on different research projects with the same French colleague (J. Dupont, Museum National d’Histoire Naturelle, Paris), they had never been involved in collaborative work prior to FBF support. FBF meetings allowed them to bring together complementary approaches to studying fungal evolution. For instance, expertise in Giraud’s group on the evolution of fungal mating systems was helpful to Berkeley grad student Chris Hann-Soden and postdoc Sara Branco. Reciprocally, expertise in Taylor’s group on fungal speciation genomics and reverse ecology was helpful to Orsay grad student Hélène Badouin and postdoc Jeanne Ropars. France-Berkeley Fund John W. Taylor Plant and Microbial Biology, University of California, Berkeley tatiana giraud Department Genetique et Ecologie Evolutive, Université de Paris-Sud Fungal Ecological Genomics As another token of the collaborative nature of the project, UC Berkeley postdoc Gladieux and PI Giraud led the writing of a review paper on fungal evolutionary genomics, involving postdocs, students and faculty from both Orsay and Berkeley. Beyond the principal French institution, l’Université de Paris-Sud, this project has created relationships with the Ecole Polytechnique. Lasting relationships between the Ecole Polytechnique and the Taylor laboratory (and more generally UCB) can be expected, given that the internship of Ms. Perraudeau was a success, that she will become a graduate student at Berkeley, and that PI Giraud teaches ecology and evolution at this school. Perhaps the most lasting accomplishment of both the FBF and MCOF is that postdoc P. Gladieux has recently won a competition to be hired as ‘experienced research scientist’ at INRA Montpellier. Gladieux will take office in January 2015. His proposed research project on Neurospora adaptive genomics complements both Taylor’s and Giraud’s research interests, and this common interest will likely foster relationships between the Taylor and Giraud labs and another French Institute renouned for evolutionary biology (BGPI lab, CIRAD, Montpellier). Annual Report 2013-2014 Final Report 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? $2777.50 was spent to support the visits of PI Giraud and postdoc Ropars to Berkeley in March 2013. $7222.50 (and a bit more charged to other funds) was spent to support the visits of PI Taylor and postdocs Gladieux and Branco to Orsay in April 2014. Gladieux recently applied to an ERC Starting grant. The proposed research involves collaboration with both Giraud and Taylor. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. One of the PIs, Taylor, was able to attend the 20th Anniversary celebration (the program, alas not the reception). He enjoyed meeting other FBF participants and encourages the FBF to hold more such meetings, as is done by the Miller Institute at Berkeley. For example, he had no idea that George Roderick and Rosie Gillespie, colleagues with similar interests, also had projects in France that might mesh with his. 87 Jeremy W. Thorner Molecular and Cell Biology, University of California, Berkeley Robert A. Arkowitz Institut Biologie Valrose, Université de Nice Sophie Antipolis Final Requirements, Molecular Roles and Distribution of Membrane R e p o r tPhospholipids in Yeast External Signal-Dependent Polarized Growth Start Date: July 2012 1) Describe the work accomplished, in relation to the original project description. On the basis of the mutual research interests of our two groups, two reciprocal visits were arranged. First, in Sept. 2012, Dr. Elodie Sartorel, a postdoctoral research fellow (and French citizen) in the laboratory of Prof. Jeremy Thorner at UC Berkeley, journeyed to the Univ. of Nice and spent a twoweek period in the laboratory of Dr. Robert A. Arkowitz. Prior to her departure, Elodie invested a significant amount of time constructing a plasmid that would be able to express a fluorescent probe to detect phosphatidylserine (PtdSer) on the cytosolic leaflet of cellular membranes in the pathogenic yeast Candida albicans, a primary organism of study in the Arkowitz group. The reason why this task is not trivial is that C. albicans and related species (referred to as the ‘CTG clade’) use a non-standard genetic code to translate nuclear genes; specifically, in this group of organisms, a CUG codon encodes Ser, whereas in the standard genetic code, CUG encodes Leu [Gomes AC et al. (2007) Genome Biol. 8: R206]. Elodie recoded the DNA sequence specifying the PtdSer- binding KA1 domain from the Saccharomyces cerevisiae protein kinase Kcc4 [Moravcevic K et al. (2010) Cell 143: 966- 977], so that the re-engineered coding sequence inserted Leu (instead of Ser) at the position of a codon that was formerly CUG as well as adhered to other aspects of the optimal codon usage bias exhibited by C. albicans. Elodie then used recombinant DNA methods to fuse the resulting CaKA1Kcc4 domain to a fluorescent protein (CaGFP) whose coding sequence was also optimized for expression in C. albicans and provided to us by Dr. Arkowitz. Elodie sent this plasmid, in advance, to the Arkowitz lab; however, no signal was visible when this plasmid was introduced by DNA-mediated transformation into C. albicans cells. Consequently, Elodie generated, using the 88 same reagents, a tandemerized construct: p[CaGFP-CaKA1Kcc4-CaKA1Kcc4-CaGFP]. Elodie also designed a C. albicans codon-optimized version of another PtdSer-binding protein, the C2 domain of the mammalian protein lactadherin, which contains 8 CUG that needed to be converted to Leu-encoding codons and was prepared for us by a commercial firm (GenScript, Inc.). In addition to sending along, in advance, to the Arkowitz lab the plasmid p[CaGFP-CaKA1Kcc4-CaKA1Kcc4-CaGFP] (in bacteria) and the CaC2Lact domain optimized for C. albicans, we also provided strains of S. cerevisiae expressing a PtdIns4,5P2-binding probe (GST-GFP-PHPLCδ1), a PtdIns4P-binding probe (GFP-PHOsh2) and a PtdSer-binding probe (GFP-KA1), as well as a fluorescently tagged version of the S. cerevisiae PtdIns4P 5-kinase, Mss4-GFP. When Elodie arrived in Nice, she wastrained on the use of the sophisticated spinning disk confocal microscope available in the Arkowitz lab and in image analysis. During this training, she examined S. cerevisiae MATa cells expressing each of the reporters (GST-GFP-PHPLCδ1, GFP-PHOsh2, GFP-KA1, and Mss4-GFP). She obtained images of the distribution and dynamics of these probes in naïve cells as well as in the same cells treated with the mating pheromone α-factor, which induces markedly polarized growth. She quantified the distribution of these probes using Matlab programs developed in the Arkowitz lab. Elodie observed that all three of the lipid-binding probes were highly enriched at the tip of the projection that forms on pheromone treated cells, whereas the enzyme Mss4 was distributed rather uniformly around the entire perimeter of the plasma membrane of the cell. After Elodie departed, Dr. Vikram Ghugtyal, a postdoctoral research fellow in the laboratory of Dr. Robert A. Arkowitz at the Univ. of Nice, incorporated the CaC2Lact domain that Elodie had prepared into a plasmid and introduced it into C. albicans and examined C. albicans cells during the marked elongation that they undergo when growing under conditions that support hyphal-form France-Berkeley Fund Jeremy W. Thorner Molecular and Cell Biology, University of California, Berkeley Robert A. Arkowitz Institut Biologie Valrose, Université de Nice Sophie Antipolis Final Report Requirements, Molecular Roles and Distribution of Membrane Phospholipids in Yeast External Signal-Dependent Polarized Growth (as opposed to yeast-form) growth. Vikram observes highly polarized localization of this reporter at the tips of C. albicans hyphal filaments. Unfortunately, no signal was observed in C. albicans using the p[CaGFP-CaKA1Kcc4-CaKA1Kcc4-CaGFP]. Second, in Dec. 2013, Dr. Vikram Ghugtyal made a twoweek visit to UC Berkeley. During Vikram’s visit, he set out to determine if the S. cerevisiae PtdIns 4-kinase encoded by the PIK1 gene was important for haploid invasive growth. To address this question, he introduced a temperature-sensitive allele (pik1-101) allele into the background of S. cerevisiae strain Σ1278b, which normally displays robust haploid invasive growh. The resulting derivative was inviable at 37°C, as expected. At an elevated temperature at which this strain still grew (35°C), no defect in haploid invasive growth was observed when that response was induced by shifting the culture to a low-glucose medium. Vikram also tried to examine the distribution of PtdSer and PtdIns4P in filamentous S. cerevisiae Σ1278b cells using S. cerevisiae-optimized reporters that Elodie routinely uses in other laboratory stocks of S. cerevisiae derived from a different lineage (S288C). However, there were difficulties in induction (with galactose) of the PtdSer reporter (under GAL promoter control) in cells that were initially propagated in glucose-poor medium to induce their filamentation. With the PtdIns4P reporter, even though its expression was driven by the constitutive PHO5 promoter, fluorescence signals were very low and difficult to detect. Interestingly, however, in liquid low/no glucose conditions, S. cerevisiae Σ1278b cells expressing the PtdIns4P reporter appeared to be completely defective for filamentous growth, whereas S. cerevisiae Σ1278b cells not carrying this plasmid behaved normally. These results suggest that plasma membrane PtdIns4P may be critical for S. cerevisiae filamentous growth, a possibility being pursued in the Arkowitz lab. Annual Report 2013-2014 2) give the names and ranks (ex. doctoral student, associate professor, etc.) of the participants in the project. • • • Elodie Sartorel, Postdoctoral Research Associate, UC Berkeley Prof. Jeremy Thorner, UC Berkeley Vikram Ghugtyal, Postdoctoral Research Associate, Univ. • of Nice Prof. Robert A. Arkowitz, Univ. of Nice 3) list all publications resulting from this project. include journal titles and issues/dates. Sartorel S, Barrey E, Lau RK, Thorner J (2014) Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway. Molecular Biology of the Cell, submitted for publication [7 July 2014] Ghugtyal V, Schaub S, Garcia R, Bassilana M, Arkowitz RA (2014) golgi phosphatidylinositol-4-phosphate- dependent membrane traffic is critical for fungal filamentous growth. Journal of Cell Biology, manuscript in preparation. 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered continuing relationships between French institutions and UC campuses. Will future collaboration occur as a result of this project? This interaction was very useful to both laboratories because there was much common ground in terms of research interests and methodological approaches. However, because the Thorner Lab focuses on Saccharomyces cerevisiae and is neither equipped to handle nor authorized to handle any experiments that involve Candida albicans, it was not possible to conduct any experiments of direct or immediate benefit to the progress of Prof. Arkowitz’s research here at Berkeley. Nonetheless, the mutual support gained by the provision and exchange of research reagents, as well as shared technical ex89 Jeremy W. Thorner Molecular and Cell Biology, University of California, Berkeley Robert A. Arkowitz Institut Biologie Valrose, Université de Nice Sophie Antipolis Final Requirements, Molecular Roles and Distribution of Membrane R e p o r tPhospholipids in Yeast External Signal-Dependent Polarized Growth pertise, was of great benefit to the research progress in both laboratories. Even though the resulting publications (see above) describe studies conducted independently in both laboratories, aspects of each project were aided, abetted and expedited by the interaction fostered by the FBF grant. It is not clear whether any formal collaboration will arise from the initial “mutual aid” pact that arose from the support provided by the FBF grant; however, we anticipate continued beneficial interactions, given our common research interests. 5) give a final accounting of how the France-Berkeley Fund award was spent. Do you envision soliciting additional outside funding for this or related projects in the future, and if yes, from where? At this point, all of the funds awarded ($10,000) have been completely expended or are completely committed, so that little significant balance remains. As of 15 May 2014 (see attached financial report prepared by Ms. Diona Cox in the Research Administration and EFA Accounting unit of MCB Business Services), Prof. Thorner’s laboratory had exhausted $4,803.50 of its allotment ($5,000) and Prof. Arkowitz had exhausted $3,721.24 of its allotment ($5,000). In the interim, the $1,278.76 remaining balance on Prof. Arkowitz’s side of the ledger was expended on the purchase of additional synthetic oligonucleotide primers (by GenScript, Inc.), which were shipped to France to aid his current work. The $196.50 90 remaining in Prof. Thorner’s side of the ledger has been spent on routine charges for supplies and expendables incurred by Dr. Elodie Sartorel in the Barker Hall stockroom. Prof. Thorner’s current NIH R01 Research Grant, which provides support for highly related projects, is due for its next 4-year renewal and an application for completing continuation of that grant has been submitted. Likewise, Prof. Arkowitz will continue to conduct studies highly related to the FBF-aided project with his support from the French National Centre for Scientific Research (CNRS) and the Institut national de la santé et de la recherche médicale (INSERM) of the Ministries of Health and Research. 6) Please give any recommendations or feedback you may have regarding the France-Berkeley Fund. I realize that funding is limited. However, at least in the hard sciences, to truly promote an authentic and lasting collaboration under such “long-range” circumstances requires far more opportunities for in-person exchange and considerably more research resources than can be supported by a grant of $10,000. So, if it were possible for the France-Berkeley Fund to obtain more total funding, and/or to give fewer but larger grants, it would likely have an even more salutary effect on fostering scholarly exchange between France and UC Berkeley. France-Berkeley Fund interim Reports Annual Report 2013-2014 91 Patricia Baquedano-López & Pedro Jose Garcia Sanchez.............................................................................................93 Social and political tools of urban cosmopolitanism: the challenge of otherness in distributed cognition and interactivity Déborah Blocker & Anne Piéjus..................................................................................................................................94 New tools and stakes for the study of language and culture in Early Modern French periodicals: the case of the Mercure Galant Jason Corburn & Gérard Salem...................................................................................................................................99 Global urban health: collaborative research for a new science of the city Wayne M. Getz & Pierre Magal ................................................................................................................................ 101 Individual-based, structually and demographically-detailed epidemic models suzenne guerlac & Jean-Pierre Montier ................................................................................................................... 102 Towards a coherently structured development of photoliterary research John Harvey & Agnès Jullien..................................................................................................................................... 103 Comparison of use phase methodology and recycling approach for pavement life cycle assessment Carl Heiles & Gilles Theureau ................................................................................................................................... 105 French / American collaboration for radio investigations of time-variable astrophysical phenomena Daniela Kaufer & François Tronche ........................................................................................................................... 106 Dissecting GR Gene Function in Stem Cells of the Nervious System Robert T. Knight and Fanny Meunier ........................................................................................................................ 107 Brain dynamics of compensatory mechanisms for lexical selection in overt speech production after left prefrontal damage lance J. Kriegsfeld & Matthieu Kelelr........................................................................................................................ 109 Neuroendocrine gating of olfactory perceptual processing Winfried Kudszus & Richard Trim ............................................................................................................................. 111 Metaphor in the political debate of austerity programs Susan G. Miller & Jocelyne Dakhlia........................................................................................................................... 113 Networking for independence: the Moroccan nationalists’ global campaign against French colonialism Elizabeth Moxon & Garance Aubry ........................................................................................................................... 114 Sudent science at synchotrons: preparing the next generation of scientists Susan J. Muller & Thibaut Divoux ............................................................................................................................. 117 Testing a generalized stability criterion for viscoelastic flows Nicholas Paige & Guillaume Peureux ........................................................................................................................ 119 The “I” before “the Self’: Non-modern uses of the first person in Renaissance and Classical France Nicolai Reshetikhin & Christian Blanchet .................................................................................................................. 120 Categorification of quantum invariants of 3-dimensional manifolds Barbara Romanowicz & Yann Capdeville .................................................................................................................. 121 Probabilistic interpretation of tomographic models Pablo J. Ross & Hélène Jammes................................................................................................................................ 123 A systems biology approach to understand parental-specific contributions to embryo and placnta development Lauren Williams & Sylvie Corteel.............................................................................................................................. 124 Tableaux combinastorics sofia Villas-Boas & Claire Chambolle ....................................................................................................................... 125 The impact of retail mergers on food prices: evidence from France 92 France-Berkeley Fund Patricia Baquedano-López Department of Education, University of California, Berkeley Pedro Jose Garcia Sanchez Sociologie, Université Paris Ouest, Nanterre – La Défense Interim Report Social and Political Tools of Urban Cosmopolitanism: The Challenge of Otherness in Distributed Cognition and Interactivity Start Date: June 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? We requested and received a no-cost extension until December 31, 2014. We have completed the first part of our proposed program, which was to hold one workshop in Nanterre, France. We organized a two-day “workshop” from April 10-11, 2014 at Université Paris Ouest, Nanterre – La Défense entitled Pragmatiques du cosmopolitisme urbain: Epreuves, ressources et interactivité. There were 27 speakers from 14 universities and institutions across 4 countries, and representing over 12 international research laboratories. The participants represented senior researchers at CNRS, junior tenured/untenured faculty, graduate students, and undergraduate students. We also had local politicians attend the workshop, including the Mayor of Nanterre and other officials from Nanterre to engage with researchers the theme of “the city.” We are currently planning a second workshop/meeting in Berkeley for the Fall 2014 where we will devote time to have a more focused exchange on work- in-progress from the Co-PIs on the themes of our shared work. The workshop in Nanterre was broadcasted live globally. It was also videotaped and there are plans underway to upload the videos of all the presentations to a website. 2) indicate how much money has been spent to date. How much do you anticipate spending? We received an award of $9,000. To date we have spent $3,961.80, which we used to cover the costs of travel and other expenses for the workshop in Nanterre. We anticipate using the remaining funds to cover the costs of the second workshop in Berkeley. Annual Report 2013-2014 3) What remains to be done for this project? When will the project be completed? We are planning the second workshop for the Fall 2014 in Berkeley, California. We hope that at that meeting, our respective research teams will identify additional venues for publication of joint work by the Co-PIs. We expect to complete the project by December 31, 2014. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. The two Co-PIs have been working closely together on all aspects of the project. They have brought student members of their respective teams together for the first workshop. They have extended their research networks across universities and research centers, and dialogue has started about future presentations and collaborations within this extended network. We also presented a poster session on the project at the France Berkeley Fund’s 20th Anniversary on May 5, 2014. At this event we discussed with attendees the nature of the project and its goals, thus introducing the project to UC colleagues and French dignitaries in attendance 5) Will this project result in a publication? (indicate form of publication, if possible.) Following the success of the first workshop in Nanterre, we are considering publishing the conference proceedings. A French publishing house is interested in the publishing the proceedings. We are also hoping to publish a collaborative piece in a refereed journal after the second workshop in Berkeley. 93 Déborah Blocker Department of French, University of California, Berkeley Anne Piéjus IReMus, CNRS I n t e r i m New Tools and Stakes for the Study of Language and Culture in R e p o r t Early Modern French Periodicals: the Case of the Mercure Galant Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The project we submitted is now half-way completed. In 2013-2014, we held two meetings, one at UC Berkeley and one in Paris. In October 2013, Anne Piéjus visited several northern Californian campuses. During this visit, she spent four days at UC Berkeley, giving a talk in the Dept. of French and talk in the Dept. of Music. We took this opportunity to present our project on the Mercure galant to graduates in early modern studies at Berkeley, in order to encourage them to participate. To this end, we organized a seminar in the French Dept (see http://french.berkeley.edu/2013/10/08/dr-anne-piejus/). In attendance were Déborah Blocker (early modern French Literature and history, French, UCB), Mairi MacLaughlin (historical linguistics, French, UCB), Anne Piéjus (musicology, IReMus, CNRS) and Claude Potts (Romance Librarian, Doe Library, UCB). During this gathering, we presented the Mercure galant to UCB graduate students and described how and where this important periodical — few complete collections of which are available in the UC — could be read and studied on-line. In particular, Claude Potts presented a detailed description of the holdings available on-line, and explained to the graduate students how these various collections could be read (in image mode) and subjected to key-word searches (in text mode, which makes vast corpora of texts searchable on-line). Anne Piéjus explained the nature and goals of the research program devoted to the Mercure galant, which she directs since 2002, detailing the on-line editions of this program (which offer a transcription of the text, a set of images and a vast indexation database, soon to be organized in ontologies). Mairi Mac Laughlin explained how periodicals like 94 the Mercure galant could be used in historical linguistics, and in what ways digitalization had opened up new possibilities in this respect. Finally, Déborah Blocker and Anne Piéjus, explained how the program funded by the FBF would unfold and invited all graduate studenta present to participate either in the study day to be organized in Paris in early June 2014 or in the gathering organized in Berkeley in February 2015. On June 3, we then held a study day in Paris on the theme: « Auctorialité, voix et publics du Mercure galant. Lire et interpréter l’écriture de presse à l’époque moderne » . This gathering took place in the salle des Commissions of the Bibliothèque nationale de France in Paris, and followed the appended schedule (which was circulated widely in French). This study day was extremely well attended (we had 21 scholars at the lunch table and over 30 in the room) and discussions both in session and during pauses were very lively. The next morning, Anne Piéjus hosted those who had taken part in June 3 meeting around a seminar table at the IReMus, for a follow-up discussion. At the opening of this 3-hour meeting, Déborah Blocker presented hypotheses and conclusions concerning the questions debated the day before, and an animated discussion ensued. Then Anne Piéjus and the members of her research group (in particular Nathalie Berton-Blivet and Alexandre de Craim) presented the extraordinarily thorough and rich indexation databases covering most of the 17th century issues of the Mercure galant, and which they have been making available on the website of the LabEx OBVIL, hosted by the University of Paris-IV. This follow-up seminar was caped by a luncheon where lively conversations continued. Many scholars working on the Mercure galant from different angles in variety of different countries expressed to us after these two June 2014 meetings how productive and inspiring these exchanges had been for them, and stressed that France-Berkeley Fund Déborah Blocker Department of French, University of California, Berkeley Anne Piéjus IReMus, CNRS Interim Report New tools and stakes for the study of language and culture in early modern French periodicals: the case of the Mercure Galant these discussions were likely to change some of their working hypotheses and research protocols. These debates also confirmed that it was important to have a more structured methodological exchange on how to read and study such serial sources in the digital age. Many participants in the Paris study days insisted on the fact that it was central, now that so many early modern sources are going digital, to carefully weigh how these new formats affect how we read such documents, and how digital tools can change the kinds of research we conduct on them. These problems will be at the center of the second international gathering we are planning, to be held in Berkeley in February 2015. 2) indicate how much money has been spent to date. How much do you anticipate spending? We have spent about half of our allotted budget ($4250) and anticipate spending the other half to organize the gathering entitled “The Mercure Galant and Early Modern Periodicals in the Digital Age: New Tools, New Research Possibilities?”, which is to take place in Berkeley in February 2015. 3) What remains to be done for this project? When will the project be completed? We still have one international meeting to organize, this time in Berkeley. It will be entitled “The Mercure Galant and Early Modern Periodicals in the Digital Age: New Tools, New Re- Annual Report 2013-2014 search Possibilities?” and is planned to take place in Berkeley in February 2015. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. This project has brought together scholars from many disciplines (history, linguistics, library sciences, musicology and literature) and has allowed for the constitution of an international network of scholars working on the Mercure galant and early modern journals more generally. It will certainly foster long-term networks and exchanges between Anne Piéjus and Déborah Blocker, and the graduate students working with them both. 5) Will this project result in a publication? (indicate form of publication, if possible.) We are planning to publish the papers given at the June 2014 in Paris in the journal XVIIe siècle, which is the top journal in French seventeenth-century studies in France, both for literary studies and for historical approaches (see: http://www. puf.com/XVIIe_siècle). Déborah Blocker has obtained a Research Assistantship in the Humanities Grant at UC Berkeley for one of her graduate students ($4000) and these funds will in part be used, during the fall of 2014, to swiftly prepare the texts to be published for their appearance in the journal. 95 Déborah Blocker Department of French, University of California, Berkeley Anne Piéjus IReMus, CNRS I n t e r i m New Tools and Stakes for the Study of Language and Culture in R e p o r t Early Modern French Periodicals: the Case of the Mercure Galant AUCTORIALITE, VOIX ET PUBLICS DU MERCURE GALANT. LIRE ET INTERPRETER L’ECRITURE DE PRESSE A L’EPOQUE MODERNE. Journées d’études organisée par l’IReMus (Institut de Recherche en Musicologie) mardi 3 juin 2014, 9h-17h30 mercredi 4 juin 2014 2014, 10h-13h Bibliothèque nationale de France, site Richelieu-Louvois 5, rue Vivienne,75002 Paris Salle des commissions, cour Vivienne Organisées par Déborah BLOCKER (Université de Californie, Berkeley et Grihl) et Anne PIEJUS (IReMus) AVEC LE GÉNÉREUX SOUTIEN DU FONDS FRANCE-BERKELEY Le projet « Nouveaux outils, nouveaux enjeux pour l’histoire de la culture et de la langue dans la presse française d’Ancien Régime : le cas du Mercure galant » porté par Déborah Blocker (Université de Californie, Berkeley) et Anne Piéjus (CNRS, IReMus) a reçu un financement du Fonds FranceBerkeley pour l’organisation de deux rencontres internationales. La première journée est consacrée à une réflexion conjointe sur les auteurs et les publics du Mercure galant, pour mieux comprendre comment cette publication était produite et à quelles types de lectures elle invitait. Les articles du Mercure galant sont le plus souvent non signés, tandis que la participation de contributeurs occasionnels ou réguliers est presque entièrement passée sous silence. Or l’écriture journalistique de Donneau de Visé, bientôt secondé de Thomas Corneille, n’est pas neutre : ils se positionnent au contraire tant vis-à-vis du pouvoir monarchique, que vis-à-vis de la société de leur temps, et leurs partis pris doivent impérativement être pris en compte aussi bien dans l’indexation du vocabulaire du discours artistique, que dans toute étude menée sur le rôle du journal dans la société du XVIIe siècle. La seconde journée d’études aura lieu à l’Université de Berkeley au printemps 2015 et sera consacrée à une réflexion méthodologique sur la digitalisation du périodique et les nouveaux types de recherche que celle-ci permet (« Le Mercure galant et les Digital Humanities. Quels outils, pour quelle recherche ? »). 96 La présente rencontre est organisée avec le soutien du Fonds France Berkeley, de la BnF et de l’IReMus. France-Berkeley Fund Déborah Blocker Department of French, University of California, Berkeley Anne Piéjus IReMus, CNRS Interim Report New tools and stakes for the study of language and culture in early modern French periodicals: the case of the Mercure Galant Mardi 3 juin 2014 (Bibliothèque nationale de France, Salle des commissions, cour Vivienne) : 9h00 : Accueil et introduction par Anne Piéjus (IReMus, CNRS) Première séance (9h15-10h45) : Genres, voix et styles dans Le Mercure galant, I. Président de séance : Alain Viala (Université d’Oxford et GRIHL) 9h15-10h : Dinah Ribard (GRIHL, EHESS) et Marion Brétéché (Université Paris IV et GRIHL) : « Qu’est-ce qu’un Mercure au temps du Mercure galant ? » 10h-10h45: Claude Bourqui (Université de Fribourg) et Christophe Schuwey (Université de Fribourg): « Des Nouvelles Nouvelles au Mercure galant : les nouvellistes comme stratégie d’énonciation » 10h45-11h : Pause Deuxième séance (11h-12h30) : Genres, voix et styles dans Le Mercure galant, II. Présidente de séance : Déborah Blocker (Université de Californie, Berkeley et GRIHL) 11h-11h45 : Jonathan Haddad (Université de Californie, Berkeley) : « Les termes et le style de l’Histoire : déontologie et esthétique des Nouvelles étrangères dans le Mercure de France » 11h45-12h30 : Alexandre de Craim (LabEx OBVIL, Université libre de Bruxelles) : « La guerre et ses dentelles. Voix et création littéraire au temps de la campagne de Hollande dans le Mercure galant (1672-1678) » 12h30-14h15 : déjeuner Troisième séance (14h15-15h45): Lectorat, anonymat et herméneutique dans le Mercure galant , I Présidente de séance : Mathilde Bombart (Université Lyon 3, GADGES et GRIHL) 14h15-15h00 : Geoffrey Turnovsky (Université de Washington à Seattle) : « Les lecteurs du Mercure galant: quelques portraits » 15h00-15h45 : Sara Harvey (Université Paris IV) : « Lecteurs, auteurs et herméneutes dans les Extraordinaires du Mercure galant (1678-1684) : la voix des abonnés » 15h45-16h00 : Pause Quatrième séance (16h00-17h30): Lectorat, anonymat et herméneutique dans le Mercure galant, II. Présidente de séance : Delphine Denis (Université Paris IV) 16h00-16h45 Elsa Véret (Université Paris IV) : « Poètes, joueurs et beaux esprits : statut et profils des auteurs d’énigme du Mercure galant » 16h45-17h30 Anne Piéjus (IReMus, CNRS) : « Poètes et musiciens. Stratégies d’anonymat et de dévoilement dans les poésies en musique du Mercure galant » Mercredi 4 juin : 10h-13 h (IReMus, salle de réunion, 2 rue Louvois, 1er étage) Réflexions conclusives sur la journée d’études (par Déborah Blocker) et discussion générale. Démonstration des éditions numériques et bases de données, par Nathalie Berton-Blivet (CNRS, IReMus), Anne Piéjus (IReMus, CNRS) et Alexandre de Craim (OBVIL, Université Libre de Bruxelles). Perspectives, par Déborah Blocker et Anne Piéjus. 13h00 : déjeuner Contacts: [email protected] et [email protected]. Annual Report 2013-2014 97 Déborah Blocker Department of French, University of California, Berkeley Anne Piéjus IReMus, CNRS I n t e r i m New Tools and Stakes for the Study of Language and Culture in R e p o r t Early Modern French Periodicals: the Case of the Mercure Galant 98 France-Berkeley Fund Jason Corburn School of Public Health & City & Regional Planning, University of California, Berkeley Gérard Salem UFR SSA, Université Paris Ouest / Nanterre Global Urban Health: Collaborative Research for a New Science of the City Start Date: September 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? We accomplished our original project goals, which were to hold two workshops/seminars in each respective institution (Paris and Berkeley) with affiliated faculty and students, and develop new collaborative projects from these seminars. PI Corburn visited the University of Paris in September and October 2013. Lectures and seminars were prepared and exchange between French and Berkeley colleagues were rewarding and fruitful. Ideas emerging from these workshops included a joint urban health research project, sharing urban health teaching strategies, and foster greater student exchanges, including inviting University of Paris doctoral students to UC Berkeley. The second large workshop was held in late February 2014. Three University of Paris scholars/faculty visited Berkeley. A 4 day workshop, including seminars with students and faculty, were held in Berkeley. New faculty from Berkeley joined the project during this time. New collaborations were developed outside of Public Health and City Planning, including those with Environmental Sciences and CITRIS. We also conducted a field visit to Richmond, CA, with the French scholars, and a new potential collaboration emerged between UC Berkeley/Richmond and University of Paris-Nanterre/and small cities around Paris. A future exchange between urban health professionals from each country, with faculty from the two universities facilitating, was another possible collaboration that emerged from this project and will sustain relationships between the French University and UC Berkeley. Finally, we have explored urban health collaborations, including data gathering and mapping, that would support the memorandum of understanding signed between the Mayor Annual Report 2013-2014 Interim Report of Paris, Bertrand Delanoë and the Mayor of San Francisco, Edwin M. Lee, focusing on smart cities. This agreement strengthens ties between the two cities and supports Inria (The French National Institute for Research in Computer Science and Control) and the CITRIS (Center for Information Technology Research in the Interest of Society, UC Berkeley). 2) indicate how much money has been spent to date. How much do you anticipate spending? All expenses were for Foreign Travel. In an effort to continue the collaboration, each side (Paris and Berkeley) are pursuing financing. The Berkeley side is exploring an NSF grant and a seed grant from CITRIS to build on the data and environmental sensing aspect of the work. The Paris team is seeking support from the laboratory Mosaiques for a Knowledge Translation to Action (KTA) project that will include an exchange between urban health professionals from both US and France that would be coordinated by academics from both Paris and Berkeley. 3) What remains to be done for this project? When will the project be completed? The proposed project has been completed. Future collaborative goals include the following: A joint-seminar on “Knowledge translation to Action” (KtA) How information moves from data to action: comparison San Francisco and Paris. • Through which types of collaboration does information move to action? • How the information needs to be produced and analysed? • How the research issues are shaped by social demand? • Is the knowledge really co-produced? • How is the knowledge applied and appropriated? 99 Jason Corburn School of Public Health & City & Regional Planning, University of California, Berkeley Gérard Salem Interim Report UFR SSA, Université Paris Ouest / Nanterre Global Urban Health: Collaborative Research for a New Science of the City This seminar would take place in Paris and be divided in three moments: • Workshop on “Knowledge translation to action” in the framework of Déclic program • Experience sharing session between stakeholders from Richmond and stakeholders from various French cities involved in health inequities reduction. • Doctoral lecture on interventional research in the cities (audience would be PhD students, researchers in urban planning) Exchanges about the pedagogy in our respective studio classes. How do we teach at the intersection of different disciplines? Which impact for the student professional integration? Which valorization within the university for master program reputation? Which support and recognition from the university? Joint classes, teaching exchange and reflection on innovative pedagogy between UC Berkeley et Nanterre University : Students of master programs could make parallel studies like: • Critical inventory of data existing in Paris & San Francisco on different health issues and their determinants. Ex: 100 which data to characterize a healthy city? Which data to deal with the specific determinants of different chronic diseases? • Describe the institutional organization and the roles of different governance levels for public health and urban planning sectors. • Comparative posters realization Meeting sF/Paris through videoconferences from september to December. US Students and Paris students could work in small groups. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. See comment #1 above. 5) Will this project result in a publication? (indicate form of publication, if possible.) None so far. France-Berkeley Fund Wayne M. Getz Department of Environmental Sciences, Policy & Management, College of Natural Resources, University of California, Berkeley Pierre Magal Institut de Mathématiques de Bordeaux, Université Bordeaux Segalen Individual-Based, Structurally and Demographically-Detailed Epidemic Models Start Date: November 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The two individuals listed above met for a week this April in Bordeaux (April 14-18, 2014) to work on the project. We narrowed down the focus of our project by, as articulated in our proposal, “scoping out epidemiological modeling problems of interest with respect to type of heterogeneities considered and potential applications.” Specifically, we settled on tackling a particular class of problems that involves making use of both “disease incidence” and “seroconversion” data to better understand epidemics. The incorporation of sero-conversion data into modeling of epidemic processes is new, because with the advent of modern genetic techniques, tests for sero-conversion have only recently become possible in monitoring the course of epidemic processes, such as influenza. These data also allow us to take a much more refined view of disease transmission with regard to heterogeneity in the size of infectious doses and in the immunological responses of individuals. 2) indicate how much money has been spent to date. How much do you anticipate spending? To date we have spent just over $3000 of the $9000 award. We anticipate spending more of these funds when Pierre Ma- Annual Report 2013-2014 Interim Report gal visits Berkeley in the Fall, and also on student assistance in analyzing data later this year. 3) What remains to be done for this project? When will the project be completed? We are currently in the stage of formulating our new model and carrying out some theoretical investigations. Later this year, we will apply the model to real data. We anticipate that our project will end in December of 2014, or carry on with a no-cost extension into the spring of 2015. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. Up to this point, this project has been an equal collaboration between the two groups in Berkeley and Bordeaux, and has been confined to interactions between the two principal investigators. Later this year, the collaboration is likely to be extended to include students within the Berkeley and Bordeaux labs. 5) Will this project result in a publication? (indicate form of publication, if possible.) Our intention is to publish the modeling work and its application to analyzing real epidemiological data in a suitable peer-review journal. 101 Suzanne Guerlac Department of French, University of California, Berkeley Jean-Pierre Montier Interim Report Lettres modernes, Université de Rennes Towards a Coherently Structured Development of Photoliterary Research Start Date: August 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? We have received an extension for our project until spring 2015, as Prof. Guerlac was on sabbatical from UCB during 2013-14. Spring 2015 Prof. Guerlac will be teaching an undergraduate course on photography and literature, which will enhance and broaden student participation in our events, reaching to the undergraduate level. She will also be teaching a graduate course on Proust that spring, to which Prof. Montier can contribute, as he has published (as has Prof. Guerlac) on Proust and photography. So far we have had a planning meeting for our events (one meeting in person, as we were both in NYC at another conference, and another by Skype) . We have finalized dates for events in early March, 2015 and decided on the names of two other participants to invite, and we have discussed possible themes for workshops that will maximize participation from colleagues at UCB in various departments. 2) indicate how much money has been spent to date. How much do you anticipate spending? No money has been spent so far. We anticipate spending close to the full amount of the award. 102 3) What remains to be done for this project? When will the project be completed? We will finalize the format for our events and precise themes for workshops. We will finalize invitations to UCB colleagues to participate as speakers. We will also try to organize a visit to the Getty Museum photography archive as part of our collaboration. The project will be completed in March 2015. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. So far, our collaboration has consisted of our planning meetings, intellectual exchanges at the conference we both attended in NYC last spring, and developing a deeper understanding of each other’s work. We have discussed additional participants (two former students of Prof. Montier and our colleague, Prof. Andrea Loselle from UCLA) who will be invited to contribute to our workshops, thus enlarging the scope of our collaboration. 5) Will this project result in a publication? (indicate form of publication, if possible.) This is under discussion. France-Berkeley Fund John Harvey Department of Civil and Environmental Engineering, University of California, Davis Agnès Jullien Laboratoire EASE, département AME, Institut français des sciences et technologies des transports, de l’aménagement et des réseaux (IFSTTAR) Comparison of Use Phase Methodology and Recycling Approach for Pavement Life Cycle Assessment Start Date: May 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The project organization is as such: UC Pavement Research Center (UCPRC) are task leaders for the use phase and Institut français des sciences et technologies des transports, de l’aménagement et des réseaux (Ifsttar) is the task leader for the construction/maintenance phase. The objectives of the project have been reached or are in progress as follows. Objective 1) Compare results of UCPRC and IFSTTAR models for use phase GHG and energy use, and identify improvements to models; The UCPRC has suggested the use of HDM4 model for the evaluation of the infrastructure use phase. Then, the Ifsttar conducted road experiments with a medium-size passenger car equipped with an air flow meter and an oil flow meter, in addition to dynamic measurements such as vehicle speed. One parameter of the infrastructure environment has been investigated in particular: the wind field influence (which is a HDM4 key parameter). Noticeable results have been found, since, for example, at a moderate speed of 75 km/h, a 30% forward wind compared to a similar no-wind case is therefore raising the fuel consumption of 18%. As a result, the Ifsttar Ease laboratory is evaluating the opportunity to acquire HDM4. This work, based on full-scale experimental data and numerical simulations, pointed out that wind influence on total aerodynamic power is noticeable for the road transportation systems and justify the necessity to take into account wind fields for modeling use phase energy of these transportation systems. The Ifsttar has presented this work at the CETRA2014 conference, and has proposed a Ifsttar-UCPRC collaboration for Annual Report 2013-2014 Interim Report this conference, but the collaboration has been slightly delayed and realized in the frame of the 2nd objective. Objective 2) Compare results of UCPRC and IFSTTAR models for materials production and construction phases for recycling strategies for GHG and energy use, and identify improvements to models, Three papers were submitted for the Pavement LCA 2014 conference to be held in Davis: 1) one for LCA ECORCE tool adaptation into an international version which will be finished by June 2014, then California LCIs will be implemented in the tool between June and October 2014, 2) the other to highlight how to include alternative materials release when they are in stockpiles or in road layers, and this in terms of ecotoxicity and toxicity impacts, a discussion will be held on this topic between Ifsttar and UCPRC over the next 6 months. 3) Finally, comparisons between various road structures were done around the world as regards energy and GHG and the results helped to work on US data for ECORCE tool. Objective 3) Establish a relationship for long-term collaboration on pavement LCA. John Harvey and Agnès Jullien decided to co-organize and co-chair the Pavement LCA 2014 conference which will be held in California on the 14th-16th of October, 2014. This conference will give the opportunity to check the actual best practice around the world for roads LCA. Several keynote speakers and industrial partners are expected. Objective 4) Demonstrate benefits of California/France collaboration to funding agencies. The collaboration leads to shared objectives and methods for pavement LCA and enrich the scientific community on actual limitations of LCA and future topics of interest. The ECORCE tool (French LCA tool) is now available in several languages 103 John Harvey Department of Civil and Environmental Engineering, University of California, Davis Agnès Jullien Laboratoire EASE, département AME, Institut français des sciences et technologies des transports, de l’aménagement et des réseaux (IFSTTAR) Interim Report Comparison of Use Phase Methodology and Recycling Approach for Pavement Life Cycle Assessment and the collaboration will help to provide a database adapted to California materials and processes including energy supply. 2) indicate how much money has been spent to date. How much do you anticipate spending? No money spent to date. Expect to spend the full amount by the end of the project. One-week trips : IFSTTAR, Agnès JULLIEN: scheduled to attend the LCA conference in Davis October 2014, and work for one week with UCPRC on LCIs The budget of Ifsttar will be fully used for that purpose. UCPRC: Arash Saboori was not able to come to France because of restrictions on his US student visa, which was the planned UCPRC spending. John Harvey is investigating the possibility of visiting Nantes in Spring 2015.s 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. UCPRC and Ifsttar have decided to continue working together with the UCPRC PhD student on data and dedicated tools as well as on alternative materials implementation considering additional indicators (not only energy and GHG). 5) Will this project result in a publication? (indicate form of publication, if possible.) • Common paper at the LCA 2014 conference • Co-chairing the LCA 2014 conference to highlight LCA practice, which will have published proceedings • Journal paper by early 2015 on full pavement LCA comparison (transport part D) 3) What remains to be done for this project? When will the project be completed? During this year, skypes were organized every month to discuss the various topics. These exchanges will continue in the second semester of 2014. 104 France-Berkeley Fund Carl Heiles Astronomy, University of California, Berkeley Gilles Theureau Station de Radioastronomie de Nançay, Observatoire de Paris French / American Collaboration for Radio Investigations of Time-Variable Astrophysical Phenomena Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? Dr G. Desvignes visited UC Berkeley for a month in October-November 2013. During his stay, he familiarized himself with the recent digital developments of the Serendip VI project. He participated in meetings and learned about the programming of the CASPER ROACH2 boards and the design of ROACH2 firmwares, among which is the Serendip VI project. With the help of Dr Siemion and other members of the CASPER group at UC Berkeley, he started to test the board on a bench lab. Dr A. Siemion came to the Nancay Radio Observatory in April 2014, where he taught a team of digital engineers and scientist about the CASPER collaboration and tools. With his expertise he helped carrying out the installation and first ‘light’ observations of the new instrumentation based on the Serendip VI project. These first observations include the observations of pulsars in a ‘search’ or incoherent mode with a large bandwidth (see plot). The project is on time regarding the proposed time line. 2) indicate how much money has been spent to date. How much do you anticipate spending? As of June 2014, $9000 have been spent in the travels and Annual Report 2013-2014 Interim Report long stays of Dr Desvignes and Dr Siemion. There will be no further expenses. 3) What remains to be done for this project? When will the project be completed? To complete the remaining observing modes of the new instrumentation, some required hardware (an Analog to Digital Converter and some computing nodes) still need to be bought by the Nancay Radio Observatory. Once this hardware is installed, limited software development will then be needed in order to test the ‘coherent’ pulsar mode and use of the commensal SETI observation mode. We hence expect a completion towards the end of 2014, early 2015. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. Thanks to his strong expertise with the CASPER collaboration, Dr Siemion gave valuable advice to the Nancay team of engineers and scientists on the ongoing digital instrumentation developments. Therefore Dr Siemion will serve as an adviser when CASPER related instruments will be developed at the Nancay Radio Observatory. 5) Will this project result in a publication? (indicate form of publication, if possible.) Once the remaining hardware has been purchased, regular observations for pulsars (surveys and timing of millisecond pulsars in the framework of the European Pulsar Timing Array) as well as commensal search for narrow band SETI signals will take place. Hence this project will most likely result in a series of papers in 2015 and beyond thanks to this new large band observing system. 105 Daniela Kaufer Department of Integrative Biology, University of California, Berkeley François Tronche « Gene Regulation and Adaptive Behaviors » team, CNRS, Université Pierre et Marie Curie, Paris Interim R e p o r t Dissecting GR Gene Function in Stem Cells of the Nervous System Start Date: 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? We have successfully achieved the aims of the original processes. The doctoral candidate Alana Wong spent several months in the Paris lab, where she generated a transgenic mouse line harboring an inducible knock-out of the glucocorticoid receptor (GR) in nestin positive adult stem cells. We have to date successfully analyzed the behavioral and cellular effects of the knock out. Although it is well known that corticosteroids, corticosterone in rodents or cortisol in humans (hereafter referred to as cort), can potently regulate neural stem/progenitor cells (NPCs), how they mediate these changes and whether it has any functional impact remains unknown. When elevated, as occurring during stress, cort can bind to two receptors, only one of which is found in NPCs1. This is the glucocorticoid receptor (GR), which can directly bind to and affect cellular DNA. We sought to determine whether chronic treatment of cort suppresses adult neurogenesis by directly acting upon GRs in NPCs or indirectly through other mediators. To investigate this, we generated a novel mouse model lacking GR gene function only in NPCs (GRNPCKO). These mice then received chronic treatment of cort through their drinking water and were examined for changes in NPC development. Additionally, we examined our GRNPCKO mice on tests that measure anxiety- and depression-like behavior, as well as cognitive skills, such as contextual fear conditioning and pattern discrimination, to determine whether changes in adult neurogenesis under chronic stress-like conditions affected hippocampal functioning. Our results not only reveal functional contributions of cell-specific GR signaling, but also 106 highlight the relevance of adult-born neurons in responding to environmental changes. 2) indicate how much money has been spent to date. How much do you anticipate spending? The full $9000 that was disbursed to the Kaufer lab has been spent. 3) What remains to be done for this project? When will the project be completed? We are currently preparing the data for publication. In June 2014 Dr. Kaufer and Dr. Wong spent several days in the Paris lab, working on the manuscript with Dr. Tronche. We hope to submit the manuscript to publication shortly. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. This project was highly collaborative and successful. Dr. Wong spent about 10 months in the Paris lab, and we helpd bi-weekly skype meetings of Wong, Tronche and Kaufer. In June 2014 Drs Kaufer and Wong visited the Paris lab again, and worked with Dr. Tronche on the preparation fo the manuscript. We have also used this meeting to design the next two projects that we will continue with. 5) Will this project result in a publication? (indicate form of publication, if possible.) Yes – we are currently preparing a manuscript for publication, and will shortly submit it to Nature Neuroscience in the form of a short communication. France-Berkeley Fund Robert T. Knight Department of Psychology, University of California, Berkeley Fanny Meunier Laboratoire sur le langage, le cerveau et la cognition, Institut des Sciences Cognitives Interim Report Brain Dynamics of Compensatory Mechanisms for Lexical Selection in Overt Speech Production After Left Prefrontal Damage Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? Our project aims at characterizing the brain dynamics of compensatory mechanisms for lexical selection in overt speech production after left prefrontal (PFC) damage. Lexical selection is the process that accesses and fits an appropriate word to ongoing speech and is key to coherent language production. Patients with left PFC damage experience major lexical selection difficulties but recover to various degrees depending on the extent of the lesion. To date, behavioral and electrophysiological data was recorded from a total of 11 left prefrontal (PFC) patients, 6 right PFC patients and 14 aged-matched controls in the tasks outlined in the proposal. The behavioral and event-related potentials (ERPs) were fully analyzed for all groups and the analysis of the time-frequency data is ongoing. The analysis of the behavioral data have shown that left PFC patients are more impaired in the Naming task than the right PFC patients or the aged-matched controls. Specifically, they show a larger semantic interference effect on error rates than the other groups. This confirms our prediction that left PFC patients are more impaired than right PFC patients and controls in lexical selection, the process by which we choose words as we speak. The analysis of the ERPs has shown a small semantic interference effect on posterior components around 300 ms post-stimulus onset. This effect was present in aged-matched controls and in right PFC patients but not in left PFC patients. This suggests the left PFC helps to solve competition at the level of lexical selection as early as 300 ms and that this top-down control may be altered in patients with left PFC lesions. These effects are however relatively Annual Report 2013-2014 small and we are now investigating whether or not there is additional information in the time-frequency domain. The analysis of the time-frequency data is ongoing. Frequency bands of interest (theta and alpha) have been determined on an individual subject basis to account for variable alpha peaks. Left-over artifacts in the different frequency bands have been identified. These were not detectable in the visual examination of the raw EEG data. Efforts have been put into writing an objective algorithm detecting unusually high power values in the frequency bands of interest. Relative to original projected timeline, data acquisition is completed and analyzes are still in progress. Stephanie Ries, post-doctorate researcher in Berkeley, has presented the existing data and results during a first meeting in Lyon in October 2013. Following this meeting, new analyzes were designed and completed. Fanny Meunier and Leo Varnet, graduate student in the Speech in Noise team, visited the Knight Laboratory in April 2014. They presented data on speech perception in noise and plasticity from their laboratory and the Berkeley dataset was discussed as well. 2) indicate how much money has been spent to date. How much do you anticipate spending? To date $4,658.80 has been spent from the initial $9,000 awarded fund. This covered Fanny Meunier and Leo Varnet’s visit to Berkeley in April 2014 (Stephanie Ries’ visit to Lyon in October 2013 was funded by other means). We anticipate spending the remaining $4341.2 to cover another visit for Stephanie Ries to Lyon at the end of the project period and to cover publication fees at the issue of the project. 3) What remains to be done for this project? When will the project be completed? We aim to complete the time-frequency analyzes of the scalp EEG data recorded in the 11 left PFC patients, 6 right 107 Robert T. Knight Department of Psychology, University of California, Berkeley Fanny Meunier Laboratoire sur le langage, le cerveau et la cognition, Institut des Sciences Cognitives I n t e r i m Brain Dynamics of Compensatory Mechanisms for Lexical R e p o r t Selection in Overt Speech Production After Left Prefrontal Damage PFC patients and 14 aged-matched controls recorded to date. We will focus particularly on Theta and Alpha amplitude recorded at frontal and posterior recording sites. Theta and Alpha power coherence analysis between frontal and posterior scalp sites will be performed to assess potential interaction between frontal and posterior sites. The percent-volume involved in the subregions of the PFC (inferior frontal gyrus and dorso-lateral PFC) will be included as a factor in these analyzes to dissociate the respective roles of these regions. The results of this final set of analyzes will be presented by Stephanie Ries in Lyon at the end of the project period. During this visit, possible publication outcomes will be discussed between the 2 groups. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. Bringing members of the two research groups together around this project has triggered substantial interest and new ideas on both sides. 108 Stephanie Ries presented the existing data and results to the members of the Neuroscience Research Center in Lyon. These data were discussed which brought new insight on the following analyzes. Fanny Meunier and Leo Varnet’s visit to Berkeley was also very rich in exchanges. They presented their data to members of the Knight Laboratory but also to members of the Center for aphasia and related disorders directed by Nina Dronkers at the VA Martinez. Leo Varnet had the possibility to discuss his ideas and data with members of both laboratories. 5) Will this project result in a publication? (indicate form of publication, if possible.) These results will lead to a publication in the form of a research report focused on the brain dynamics of compensatory mechanisms for lexical selection in overt speech production after left prefrontal damage. We note that the analysis of the behavioral results have already generated a manuscript which is currently in revision. France-Berkeley Fund Lance J. Kriegsfeld Department of Psychology, University of California, Berkeley Matthieu Keller Laboratoire de Physiologie de la Reproduction, Université de Tours Neuroendocrine Gating of Olfactory Perceptual Processing Start Date: January 2014 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? Despite the pronounced importance of olfaction in mammalian reproductive function, the precise neural pathways coupling pheromonal processing to the neural network controlling mammalian fertility and mate selection in the hypothalamus are not well understood and further research is needed to explore this question broadly impacting human and non-human animals.Conspecific sex pheromones from a suitable mate trigger a short-term increase in sexual motivation in reproductively active animals. However, when non-reproductively active animals are provided with the same pheromonal stimulus, sexual motivation and behavioral output are suppressed, pointing to an obstruction of pheromonal information flow in this neural circuit. We are presently exploring the notion that reproductive behavioral and motivational state is, in part, a consequence of olfactory processing of reproductive-relevant, pheromonal communication by two reproductive neuropeptidergic systems, one stimulatory system expressing kisspeptin (Kp) and the other inhibitory and expressing gonadotropin-inhibitory hormone (GnIH). Our plans have not deviated from the original proposal. As originally planned, Syrian hamsters have been exposed to either long (16 hours of light/day) or short (8 hours of light/day) day lengths for 10 wk to generate animals that are reproductively competent or inhibited, respectively. Half of the animals in each photoperiod were exposed to clean bedding whereas the remaining animals in each condition were exposed to bedding from reproductively active females. We are presently examining the olfactory reproductive axis in the brains of these animals to determine whether information flow is blocked at the level of olfactory receptors Annual Report 2013-2014 Interim Report in reproductively quiescent animals or downstream portions of the circuit, including Kp and GnIH. 2) indicate how much money has been spent to date. How much do you anticipate spending? ~$4,500 has been spent to date on reagents for the projects and on travel for Dr. Kriegsfeld and his graduate student to Dr. Keller’s laboratory in Tours. We anticipate spending the remainder of the funding (~$4,500) to permit Dr. Keller and his graduate student to visit the Kriegsfeld laboratory at Berkeley as well as purchase the remaining reagents required to complete the projects. 3) What remains to be done for this project? When will the project be completed? We anticipate that the projects will require approximately 6 more months to complete. Neural tissues have been collected and are presently being processed using double- and triple-label immunofluorescence. Microscopy and computer-aided analysis of images from the primary and accessory olfactory bulbs, amygdala, and several nuclei of the hypothalamus are presently being examined. We are also examining the state of two specific neuropeptidergic systems, Kp and GnIH, as described above. Once data collection is complete, data analysis will be conducted within the ~6 mo time frame. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. The experiments being conducted combine the expertise of Dr. Keller (olfaction and neuroendocrinology) with that of Dr. Kriegsfeld (female sexual behavior and neural circuit investigation). Without the intellectual and technical expertise of both parties, these studies will not be possible. A subset of 109 Lance J. Kriegsfeld Department of Psychology, University of California, Berkeley Matthieu Keller Interim Report Laboratoire de Physiologie de la Reproduction, Université de Tours Neuroendocrine Gating of Olfactory Perceptual Processing the work is being performed at each location with the Kriegsfeld group helping the Keller group during our recent visit to the Tours group – and the Tours group imparting assistance required by the Kriegsfeld group. Additionally, we both have colleagues interested in questions in behavioral endocrinology, with the recent visit to Tours allowing the Kriegsfeld group to discuss novel projects of mutual interest with other members of the Tours group in addition to Dr. Keller and his lab. When Dr. Keller and his student visit Berkeley, they will be introduced to researchers with common interest on the Berkeley campus to facilitate similar collaborative work with 110 UC Berkeley. We both expect that such a relationship will forge continued, exciting collaborative efforts with several faculty at Berkeley and the French laboratory in Tours. 5) Will this project result in a publication? (indicate form of publication, if possible.) No matter what the outcome of the experiments, the results will be informative and enhance our understanding of olfactory processing. The results will be published in an experimental report in a peer-reviewed scientific journal. France-Berkeley Fund Winfried Kudszus Department of German, University of California, Berkeley Richard Trim Faculté des Lettres et Sciences Humaines, Université de Toulon Metaphor in the Political Debate of Austerity Programs Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The project has advanced significantly in several key respects: 1) A comparative analysis between France and the USA in terms of austerity-related family metaphors with regard to presidential speeches, both diachronically and synchronically: with special consideration of George Lakoff ’s (senior team member) metaphor analysis, Richard Trim (PI France/Toulon) has been investigating the cognitive linguistics of political uses of family imagery for advancing moves toward austerity. Time and culturally inflected space figure prominently in this investigation. 2) In a well-attended workshop at UC Berkeley this April 2014, Winfried Kudszus (PI Berkeley) discussed metaphors of lack in literature, culture and philosophy, with special reference to the language philosopy of Ludwig Wittgenstein and the writings of Franz Kafka. Among the participants in the workshop were the junior team members, Ashwin Manthripragada and Emina Musanovic. Configurations of space and constructions of emptiness were highlighted in these discussions. 3) Employing terminologies of cultural semiotics, Daina Teters (senior team member) has investigated philosophical notions of emergent time & space in a deep diachronic spectrum related to configuratons of emptiness from Greek antiquity to 20th century thought. 4) Ashwin Manthripragada (junior team member) has analyzed conceptual uses of “austerity and lack” in artistic production and religious discourse in their evaluatively charged interfaces with economic spheres: austerity and lack are frequently treated as virtues in religious discourse and even as inspiration with regard to artistic production. Annual Report 2013-2014 Interim Report 5) Emina Musanovic (junior team member) has engaged in culturally inflected ecopoetics of the metaphorical uses of “austerity” and “lack”, pointing out creative impulses and turns in apparently “empty” economic configurations. Regarding the overall direction of the investigation, time and space have emerged as central coordinates that allow for the theoretical and applied charting of different usages and evaluations of austerity and lack in economical, linguistic, literary and philosophical discourse. Progressing within the project proposal’s overall timeframe, the project is on its way toward an international conference, presently planned for early fall 2014, which will highlight and disseminate team findings. 2) indicate how much money has been spent to date. How much do you anticipate spending? Approximately $600 will be drawn by the junior members of the Berkeley team, Ashwin Manthripragada and Emina Musanovic, for work already performed. We anticipate an additional $1,200 for further work by these two members, for a total of $1,800. The remaining $6,200 of the $8,000 budget are set aside for the conference costs. 3) What remains to be done for this project? When will the project be completed? Further work as accentuated in items 1 - 5 of question #1 remains to be done. We are aiming for a preliminary project completion by October 1 this year, per the current proposal deadline. However, with a view toward the publication of our considerations, we expect our joint work to continue beyond this date. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continu111 Winfried Kudszus Department of German, University of California, Berkeley Richard Trim Interim Report Faculté des Lettres et Sciences Humaines, Université de Toulon Metaphor in the Political Debate of Austerity Programs ing relationships between French institutions and UC campuses. In its wide synchronic and diachronic reach, this project relies on the collaboration of its various participants. Cognitive linguistics in a diachronic, culturally differentiated spectrum significantly informs the methodology of the French PI, while the UC PI moves in the interdisciplinary realm strongly developed on the UC campuses. In the collaboration of the team members, French in-depth meticulous analysis and California 112 boundary dissolutions produce new insights into the persistent presence—and semiotically articulate absence—of austerity and lack in political and metapolitical contexts. 5) Will this project result in a publication? (indicate form of publication, if possible.) We expect the publication of scholarly articles and of a book containing contributions from the project participants. France-Berkeley Fund Susan G. Miller Department of History, University of California, Davis Jocelyne Dakhlia Centre de Recherches Historiques, L’Ecole des Hautes Etudes en Sciences Sociales Networking for Independence: The Moroccan Nationalists’ Global Campaign Against French Colonialism Start Date: June 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? David Stenner, a PhD candidate in Middle East and North African History, successfully conducted several months of archival research in France. He worked at numerous repositories, including the Centre des Archives diplomatiques in Nantes (44), the Centre François Mauriac in St-Maixant (33), the Archives diplomatiques in La Courneuve (93), the Service historique de la défense in Vincennes (94), the Archives nationals in Pierrefitte-sur-Seine (93), as well as the Bibliotheque nationale, the Institut d’histoire du temps présents, and the Centre d’histoire de Sciences-Po all located in Paris. Moreover, he conducted research at both the US National Archives in College Park (MD) and the Library of Congress in Washington DC upon his return to the USA. He accessed numerous collections pertaining to the French Protectorate in Morocco, especially regarding the international activities of the native nationalist movement. After taking photos of all relevant documents, he translated them and began to write up his findings, which he is currently turning into the seven chapters of his dissertation. Once the tenure of the FBF grant expired at the end of September 2013, David Stenner remained in Paris until 2 February, 2014, paid for with a minor research grant awarded by the Department of History in the spring of 2012 as well as personal savings. In addition to working on his dissertation, David Stenner also wrote an article on the Moroccan nationalist movement, which is scheduled to appear in October 2014. This publication is based on research conducted both before and during his tenure as a FBF grantee. Of course, he acknowledges the financial support he has received from the Fund in his artiAnnual Report 2013-2014 Interim Report cle. Furthermore, he will present his work at both the annual meetings of the Middle East Studies Association (MESA) in November 2014 and the American Historical Association (AHA) in January 2015. 2) indicate how much money has been spent to date. How much do you anticipate spending? All of the money has been spent. 3) What remains to be done for this project? When will the project be completed? The project has been completed. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. In addition to his research, David Stenner participated actively in the academic life of Paris. He regularly attended seminars, public lectures, and workshops both at the EHESS and Sciences-Po, thus obtaining an understanding of French academia, broadening his knowledge on North Africa, and making professional contacts among French academics. Due to his extended stay in France, he is now capable of communicating fluently in French. He will continue to benefit from this experience throughout his professional career, because the contacts he made will be useful in organizing conference panels and organizing collaborative research projects. 5) Will this project result in a publication? (indicate form of publication, if possible.) David Stenner, “Did Amrika promise Morocco’s Independence? The Sultan, the Nationalist Movement, and the Making of the Roosevelt Myth,” Journal of North African Studies (forthcoming – expected October 2014). 113 Elizabeth Moxon Advanced Light Source, Lawrence Berkeley National Laboratory Garance Aubry Interim Report Synchotron SOLEIL, St. Aubain, France Student Science at Synchrotrons: Preparing the Next Generation of Scientists Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The project was divided into three stages, and we have successfully completed the major framework activities of the proposal: Stage 1: The first symposium was held SOLEIL Synchrotron in October 2013, where participants analyzed the inventory of existing activities, with presentations about current activities from several light sources as well as input from education and public outreach specialists active in high school student projects at synchrotrons, along with the educational researchers (and teachers) to guide and categorize the presented activities. During this meeting, a detailed questionnaire was developed with the input of the more than 20 attendees. It has been sent to synchrotrons around the world that are active members of lightsources.org—the international collabora- 114 tion of light source communicators—to collect information on existing activities and educational materials. Participants at the first meeting included teachers, scientists and representatives from the Advanced Light Source (US), ESRF and SOLEIL (France), Diamond Light Source (UK), Photon Factory (Japan), Canadian Light Source, Australian Light Source, and Elettra (Italy). Stage 2: The “Synchrotron Education Collaboration Survey” has been sent to 18 light source education/outreach specialists. Organizers of this project are currently interviewing each contact personally, and collecting examples of educational materials (print, multimedia, etc.) for inclusion in the final report. The findings will be analyzed once all interviews are completed. Preliminary analysis has been completed on results; interviews are ongoing. Stage 3: A second mini-symposium in May 2014 heard presentations from teachers and students who have conducted experiments at the ALS, as well as from LBNL outreach specialists. In addition, participants reviewed preliminary results form the survey of educational activities. Once all results are in, the information will be collected in the form of a catalogue from which a proposed list of best practices and recommendations is derived. To further promote this work outside of this proposal, organizers would also include a presentation of the report to the board of lightsources.org in the form of a symposium at the 2015 AAAS Annual Meeting to be held 12-16 February in San José, CA. The project is behind in the projected timeline owing to the fact that two of the principals—Claus Habfast (ESRF) and Marie-Pauline Gacoin (SOLEIL)— have left their positions, but the enthusiasm of the participants from `other light source facilities is moving the project forward. There is tremendous interest and cooperation from several European, Australian, Asian, and North American light sources. France-Berkeley Fund Elizabeth Moxon Advanced Light Source, Lawrence Berkeley National Laboratory Garance Aubry Synchotron SOLEIL, St. Aubain, France Student Science at Synchrotrons: Preparing the Next Generation of Scientists Interim Report Students at Synchrotron SOLEIL Students at the Advanced Light Source 2) indicate how much money has been spent to date. How much do you anticipate spending? We have spent approximately $4300, mostly for travel. It is hoped that a final meeting will be held to conclude the production of the catalogue, and to write a paper on the results. This will require at least one Berkeley-France trip, with an estimated cost of $2000-$2500 (depending on airfare costs and where the meeting is held. ing relationships between French institutions and UC campuses. The enthusiasm for this collaboration from the outset has been instrumental in pushing it forward, despite the departure of two principal members shortly after the first symposium. Marie-Pauline Gacoin and her team at SOLEIL synchrotron have contributed both time and effort in not only hosting the first meeting, but in contributing input and analysis of the survey results. My colleague at ESRF, Claus Habfast, until elected to the Grenoble City Council, has been an outstanding font of ideas and support, and he continues to offer advice when his schedule permits. This collaboration has not only strengthened the France-Berkeley relationships, but has expanded its impact around the world by engaging more than 20 facilities’ representatives. By involving educational and outreach specialists from so many different scientific research facilities to participate, we have expanded the reach of this program and fostered new and exciting relationships. 3) What remains to be done for this project? When will the project be completed? Several interviews remain to be completed, once done the results will be added to preliminary results and analyzed for the production of a “best practices” catalogue of educational materials. Anticipated completion is Fall 2014. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuAnnual Report 2013-2014 115 Elizabeth Moxon Advanced Light Source, Lawrence Berkeley National Laboratory Garance Aubry Interim Report Synchotron SOLEIL, St. Aubain, France Student Science at Synchrotrons: Preparing the Next Generation of Scientists 5) Will this project result in a publication? (indicate form of publication, if possible.) It is intended that the results of the project, including a completion of the analysis of effective educational programs at 20 synchrotron facilities, will be published in a variety of print and online publications: • Synchrotron Radiation News (print—has an education-only issue) • lightsources.org (web site dedicated to synchrotron facilities world wide; more than 65 participating facilities representing more than 100,000 scientists, students, and engineers) • Public Communication of Science and Technology (PCST 2014) A paper was accepted for a session at the 2014 116 meeting in Brazil; while none of the participants were able to attend, a panel member presented an overview of this project. (http://www.pcst-2014.org/images/ abstract_13thpcst.pdf; session 20667 “Outreach and Science Programs in Informal Settings: The Role of Children’s Universities and Similar Initiatives to Engage Young Audiences.” A description of the project and acknowledgement of FBF is found on page 42 in the abstract book.) France-Berkeley Fund Susan J. Muller Department of Chemical and Biomolecular Engineering, University of California, Berkeley Thibaut Divoux Centre de Recherche Paul Pascal Testing a Generalized Stability Criterion for Viscoelastic Flows Start Date: August 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? This project focused on testing a generalized stability criterion for viscoelastic fluids using flow between concentric, rotating cylinders (the Taylor-Couette problem) as the platform. The generalized criterion proposed by McKinley and co-workers seeks to explain the non-monotonic effects of fluid elasticity on the stability of any flow with curved streamlines by describing both the inertial (centrifugal) and the elastic contributions to flow destabilization. The Taylor-Couette geometry, in which either the inner or outer cylinders can be rotated, provides a useful tool for systematically varying the influence of inertial effects; elastic effects are varied through the choice of the test fluid. Divoux visited UCB for 4.5 months starting in August 2013, and we initiated a series of experiments in Muller’s laboratory, using a custom-built cell that was uniquely suited to examining the parameter range of interest. This parameter range included highly elasticity flows, and we progressively increased the influence of elasticity through increasing concentration of a polymeric solute. Divoux conducted detailed experiments in regimes of outer cylinder Reynolds number and elasticity that have not been previously explored, and collected tremendous amounts of raw data on the flow fields and their evolution. Although we did not achieve sufficient elasticity to observe the predicted transition from stable to unstable flows at vanishing inner cylinder Reynolds number and increasing elasticity and outer cylinder Reynolds number, we identified a number of elastic modifications to the critical conditions for flow transitions as well as new flow dynamics in these highly elastic flows. Muller is currently visiting Divoux’s laboratory (for one month, June 2014) in Bordeaux Annual Report 2013-2014 Interim Report where we are analyzing the data obtained last winter and planning future studies. This latter visit was funded through a visiting scientist position funded by the French Agence Nationale de la Recherce through a LabEx (laboratory center of excellence) associated with the University of Bordeaux. We plan to continue experiments by involving a current Berkeley postdoctoral scientist and using fluids of still higher elasticity, and we are working to identify funding to continue the collaboration. 2) indicate how much money has been spent to date. How much do you anticipate spending? To date we have expended the $9000 budget. Funds were spent, as indicated in our modified budget of July 14, 2014, primarily on supporting Dr. Divoux’s local expenses (rent) during his 4.5 month stay in Berkeley, and on providing support for Divoux and an additional collaborator, Professor Sandra Lerouge of Universite Paris – Diderot / CNRS, to attend the Society of Rheology conference in October, 2013, in Montreal, Canada. At that meeting, the three of us (Divoux, Lerouge, and Muller) were able to discuss the ongoing experiments and future plans. As noted above, we have already received some additional funding to support a month-long visit by Muller to Divoux’s laboratory in Bordeaux, and we are using the visit also to identify more permanent funding for a longer-term collaboration. 3) What remains to be done for this project? When will the project be completed? We anticipate some further (spectral) analysis of the existing data to quantitatively identify stability boundaries and the spatio-temporal symmetry of disturbance flows in the elastically dominated flows we have studied to date. In addition, we hope to extend the experiments to higher elasticity in order to observe the predicted change in stability at vanishing 117 Susan J. Muller Department of Chemical and Biomolecular Engineering, University of California, Berkeley Thibaut Divoux Interim Report Centre de Recherche Paul Pascal Testing a Generalized Stability Criterion for Viscoelastic Flows inner cylinder Reynolds number. These latter experiments would provide a more critical test of the generalized stability criterion than we have been able to perform so far. We anticipate the project will continue throughout the next 12-18 months; we anticipate that the collaboration will continue beyond the current project. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. The project has promoted a collaboration between Divoux and Muller, who were introduced to one another via email by mutual collaborators but had not met or worked together prior to preparing the France-Berkeley Fund proposal. Divoux’s very productive visit to Berkeley included not only the proposed Taylor-Couette experiments described above, but also included participation in research group meetings and seminars in the greater fluid dynamics community at Berkeley, and many discussions with Muller about problems related to complex fluid dynamics. Of particular interest were preliminary experiments Divoux conducted at Berkeley on visco- 118 elastic drops falling in miscible fluids. Here, a series of shape changes occur as the drop falls, followed by fragmentation instabilities. (The latter have been studied for Newtonian fluids by Arecchi and co-workers, see for example Eur. Phys. J. Special Topics 146, 357-374 (2007).) The collaboration has been strengthened by Muller’s visit to Divoux’s laboratory at Centre de Recherche Paul Pascal in Bordeaux, during which we also pursued falling drop experiments with the help of an undergraduate student. During Muller’ s month-long stay in Bordeaux, Divoux facilitated numerous meetings with other potential collaborators who share research interests in soft matter and microfluidics. We have also identified some funding opportunities through the University of Bordeaux that we will pursue in order to continue the viscoelastic drop experiments. 5) Will this project result in a publication? (indicate form of publication, if possible.) We are currently planning to publish work from the preliminary experiments in an archival, peer-reviewed journal, possibly Soft Matter, Physical Review E, or Europhysics Letters. France-Berkeley Fund Nicholas Paige Department of French, University of California, Berkeley Guillaume Peureux Littérature française, Université Paris 10 -Nanterre The “I” before “the Self”: Non-Modern Uses of the First Person in Renaissance and Classical France Start Date: October 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? Project has been completed. Two workshops were held, one in Berkeley (Feb 28-29, 2014), one at Paris 10-Nanterre (May 6-7, 2014). Three researchers traveled from France and three Berkeley researchers traveled to France. There was some alteration to the original timetable, which called for holding the first workshop in Fall 2013; this turned out to be unfeasible, given the date the award was announced. 2) indicate how much money has been spent to date. How much do you anticipate spending? All funds have been spent on the travel and lodging of participants. Some additional funds have been contributed by the project initiators and participants to cover meals and lodging. 3) What remains to be done for this project? When will the project be completed? The project is completed. Annual Report 2013-2014 Interim Report 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. The workshop format was designed to foster a true working relationship among participants, who were encouraged to present work in progress. Researchers from variety of ranks were able to meet on equal footing in such an environment: each workshop was composed of doctoral students and early, mid, and late career professors. We were also able to bring two Swiss researchers (one doctoral student, one early career professor) to the table as well. 5) Will this project result in a publication? (indicate form of publication, if possible.) After reflection, we have decided not to pursue the publication of a volume of proceedings. However, we expect that the majority of participants will seek to publish versions of their papers as peer-reviewed articles and we will report back on their status. One participant has web-posted his contribution as an open access working paper. 119 Nicolai Reshetikhin Mathematics, University of California, Berkeley Christian Blanchet Interim Report Mathematique, Université Paris Diderot Categorification of Quantum Invariants of 3-Dimensional Manifolds Start Date: January 2014 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The first step of the project is completed. The R-matrix for quantum sl_2 at the second root of unity is computed and its properties are studied. As a result invariants of knots and tangles with coefficients in an SL_2 C local system are constructed. These invariants are expected to be generalized Alexander polynomials, or so called twisted torsions. We expect to finish a paper with these results in the Fall 2014. We also started the second step of the project which is to construct invariants of 3-manifolds with flat SL_2C connections. We expect that these will be twisted torsions. The categorification of these invariants is the third step of the project. Because the invariants in question have both combinatorial and geometrical description we expect that both methods should work in the categorification. The project went according to the original time line. Hoel Queffelec and Christian Blanchet visited Berkeley. Hoel stayed for about two month. Nicolai Reshetikhin visited them in Paris. The collaboration on the project will continue. Both Christian Blanchet and Nicolai Reshetikhin are enthusiastic to continue the collaboration on related projects as well. 120 2) indicate how much money has been spent to date. How much do you anticipate spending? Most of the money has been spent by now. Further collaboration will be funded by other grants. 3) What remains to be done for this project? When will the project be completed? Step one (construction of invariants of tangles) is completed and the paper is expected in the Fall. Step two is well under way and we expect a paper on this in the Spring 2015. The third step, the categorification, in the most difficult part. But we have made partial progress on this. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. All three of us worked together, very productively, and we all expect that collaboration will go far beyond the duration of the grant. 5) Will this project result in a publication? (indicate form of publication, if possible.) Yes, there will be at least two papers in research journals coming out of this collaboration. France-Berkeley Fund Barbara Romanowicz Department of Earth and Planetary Science, University of California, Berkeley Yann Capdeville CNRS, LPG Nantes, Université de Nantes Probabilistic Interpretation of Tomographic Models Start Date: July 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? For more than 30 years, seismologists have constructed images of the Earth from seismic waves generated by earthquakes. The resolution of these images is limited by the computational power available. Although we know the Earth contains sharp discontinuities, the recovered images are smooth and can only be seen as spatial averages. This project consists of two parts: 1) develop an algorithm to assess the probability of seismic structure given the smooth images that are observed; 2) Apply this methodology to the global tomographic models constructed in the last few years at Berkeley. The theoretical development has been done by Postdoc Thomas Bodin (Berkeley) and Yann Capdeville (Nantes) during Capdeville’s visit to Berkeley in Summer 2013. The algorithm has been implemented, tested and verified by Bodin after Capdeville’s visit. A Fortran code will be made available to the public soon. The methodology has been applied to a tomographic model under North America, and first results indicate that the discontinuities in the upper mantle may significantly contribute to the observed anisotropy in tomographic models. Interpretation of results has been extensively discussed with senior researchers having a long expertise on these problems: Barbara Romanowicz at Berkeley, and Jean-Paul Montagner at IPGP Paris. Overall, the main goals set up in the project have been achieved on time. A publication is accepted and another is in preparation. Annual Report 2013-2014 Interim Report 2) indicate how much money has been spent to date. How much do you anticipate spending? To date, $7300 have been spent. The money was used to fund Capeville’s 6 weeks visit to Berkeley on summer 2013, and Bodin’s visit to Paris (IPGP) in March 2014. These travels enabled fruitful discussions between members of the project. We expect to spend the remaining funds on the costs of publication. 3) What remains to be done for this project? When will the project be completed? This work is in essence the introduction of an entirely new methodology in seismology, and has represented a timely and exciting project. The preliminary 1-dimensional results obtained under North America have produced new insights into the seismic structure of the mantle. Clearly, the long term goal is to extend the procedure to the 2D and 3D cases, and perform this at the global scale. It is a huge task which is beyond what could be achieved in one year. The preliminary results are very encouraging, and Capdeville, Bodin, and Romanowicz plan to keep working together in the next few years. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. Currently, only a few groups worldwide are developing such approaches for interpretation of tomographic models. This work has resulted from the combination of Berkeley’s competences in tomographic model construction, together with French expertise on elastic homogeneization. In this way, this project has initiated a long term collaboration between the global seismology group at Berkeley led by Romanowicz and French researchers (Capdeville, Montagner). 121 Barbara Romanowicz Department of Earth and Planetary Science, University of California, Berkeley Yann Capdeville Interim Report CNRS, LPG Nantes, Université de Nantes Probabilistic Interpretation of Tomographic Models Furthermore, Berkeley postdoc Bodin will start working at CNRS in 2015 at ENS Lyon, and will keep close contact with the Berkeley group. We expect the collaboration to continue as a result of this work. To carry on with this project, other forms of funding will be requested both in the US (NSF), and in France (ERC, ANR). 5) Will this project result in a publication? (indicate form of publication, if possible.) Results from this project were presented at the American Geophysical Union Fall meeting on December 2013 in San Francisco. 122 An invited contribution to a monograph has been written and accepted for publication: interpreting Radial Anisotropy in global and Regional tomographic Models T Bodin, Y Capdeville, B Romanowicz, JP Montagner. Book Chapter. The Earth’s heterogeneous mantle. A Khan, F Deschamps & K Kawai (eds), Springer, in press. A manuscript describing the methodology in detail is in preparation, and will be submitted to Geophysical Journal International shortly. France-Berkeley Fund Pablo J. Ross Department of Animal Science, University of California, Davis Hélène Jammes Unité Biologie du Développement et Reproduction, INRA A Systems Biology Approach to Understand Parental-Specific Contributions to Embryo and Placenta Development Start Date: September 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? The objective of our project is to characterize the respective contribution of the paternal and the maternal genomes to the transcriptional and epigenetic profiles in different tissues. This project aims to identify allele expression imbalance in cattle and hypothesizes that epigenetic modifications could be involved in this general process, as well as for imprinted genes. An experimental design was established taking into account the implication and the competences of both American and French teams. Unfortunately, our grant application to ANR (France; ANR- PCS-09-GENM-022) was not funded; resulting in a high selection of projects due to a decrease of research funding in France. However, data were produced. Firstly, we re-focused our study on the conservation of paternal and maternal genomes contribution after nuclear transfer. Namely, whole genome sequencing of 16 individuals produced by nuclear transfer (individuals genetically identical but epigenetically different as well as the monozygotic twins) and of the cow, given the somatic cells to cloning are in progress. Whole genome sequencing of the father of the cow is also in progress. For all cloned individuals (pathological and normal), the epigenetic profiles (DNA methylation) in muscle could be established (in progress). One aim of the collaborative project is to combine epigenetic analysis (performed in France) and RNA sequencing (performed in Davis) from the same biological muscle samples. The bioinformatics analysis of this set data will be performed in the next six months. An alternative approach was used to identify allelic specific gene expression in Bos Taurus x Bison bison embryos produced in Davis. Data was acquired by RNA-seq of blastocyst stage embryos and is currently under bioinformatics analysis. Based on Annual Report 2013-2014 Interim Report the allelic expression of RNA (identified using SNP between the both breeds), these data could provide a list of potentially imprinted genes, genes with mono allelic expression. Firstly, by in silico analysis, CpG rich regions could be determined and analyzed by bisulfite/pyrosequencing in order to identify differentially methylated regions involved in the monoallelic expression. Given the delays accessioned by diminished funding a 6 month extension to the FBF project will be requested. 2) indicate how much money has been spent to date. How much do you anticipate spending? No FBF funds have been spent so far. We anticipate that Dr Jammes and a student from INRA will visit the UC Davis lab in November 2014 and Dr Ross and a UC Davis student will travel to France in January 2015. 3) What remains to be done for this project? When will the project be completed? We plan to perform bioinformatics analysis and bisulfite /pyrosequencing validations. We plan to submit a new grant application in France (December 2014) to seek funding to complete this project. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. Complementation of expertise between UC Davis and INRA is the pillar of this project, and as data is being gathered in France and analyzed at UC Davis the synergistic efforts will be fully realized. 5) Will this project result in a publication? (indicate form of publication, if possible.) We expect the results from this project will be published in a peer-review scientific journal. 123 Lauren Williams Department of Mathematics, University of California, Berkeley Sylvie Corteel Interim Report LIAFA, CNRS and Université Paris Diderot Tableaux Combinatorics Start Date: January 2014 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? Olya Mandelshtam, a student of Lauren Williams, has been making progress on some aspects of the project. She has discovered a beautiful determinantal formula for the number of Catalan tableaux of a given shape. This in turn gives an explicit formula for the probability of being in each state of the ASEP in the steady state. She is now working on understanding the Markov chain on tableaux that was constructed by Corteel and Williams. More specifically, she is trying to understand what the individual tableau can say about the trajectories in the ASEP that led to that state. Sandrine Dasse-Hartaut, a student of Sylvie Corteel, has been workimg during her whole PhD on the combinatorics of staircase tableaux. Williams was one of the referees of the thesis which was defended in June 2014. Dasse-Hartaut got a one-year instructor position for 2014-2015 and will work on the FBF project. Dasse-Hartaut got recently inspired by the the PhD thesis of Lazarescu (CEA Saclay) on the cumulants of the current in the ASEP. This work seem to show that the combinatorics of twin Catalan tableaux plays a role. Thanks to the work of Mandelshtam, Dasse-Hartaut showed that twin tableaux also have a determinantal formula and are related to Baxter permutations. She is now attacking in collaboration with Corteel a project on twin staircase tableaux and hopes to relate this to moments of orthogonal polynomials. When Mandelshtam will visit Paris, they will collaborate on this project which fits perfectly in the FBF proposal. However, the project is still in early stages. The project will begin more seriously in August 2014 when Sylvie Corteel 124 visits Lauren Williams in Berkeley. Subsequently, Lauren Williams and her students will spend much of the academic-year 2014-2015 in Paris, working with Corteel. 2) indicate how much money has been spent to date. How much do you anticipate spending? So far we have not spent any of the money. We are saving the money to use during August 2014, when Corteel visits Williams in Berkeley, and also during the academic year 20142015, when Lauren Williams will be on sabbatical and will visit Paris (along with several of her students). 3) What remains to be done for this project? When will the project be completed? A main direction of the project that has not yet been touched is the connection between the ASEP and orthogonal polynomials, especially the Macdonald polynomials. We anticipate that the project will be completed in August 2015. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. The project will involve collaborations between Corteel, Williams, and their students. Olya Mandelshtam and Steven Karp (both of whom are students of Williams) will be in Paris in Fall 2014, and will work together with Corteel, her student Francois Nunzi and Sandrine Dasse-Hartaut, and Williams. 5) Will this project result in a publication? (indicate form of publication, if possible.) This project will result in several publications in research journals. France-Berkeley Fund sofia Villas-Boas ARE, University of California, Berkeley Claire Chambolle INRA, ALISS, Institut National de la Recherche Agronomique The Impact of Retail Mergers on Food Prices: Evidence from France Start Date: July 2013 1) What is the current status of the project? What has been achieved? How does this relate to the original projected timeline? We have finished the first version of a research paper that we are going to submit to a top journal. We have presented our work at many research universities and institutions and have received very positive feedback. We are within our original timeline. We have benefitted from feedback from Emek Basker, Cyndi Berck, Kurt Brekke, Tim Bresnahan, Christine Boizot, Christophe Bontemps, Stéphane Caprice, Liran Einav, Mahdiyeh Entezarkheir, Fabrice Etilé, Philippe Février, Nancy Gallini, Pedro Gardete, Rich Gilbert, Guido Imbens, Jakub Kastl, Laurent Linnemer, Valérie Orozco, Mar Reguant, Vincent Réquillart, Patrick Rey, Mike Riordan, Morten Saethre, Cael Warren, Dennis Yao, and participants at the IIOC, ESEM, EARIE, ANR-DFG workshop in Düsseldorf, Peder Sather IO Workshop at Berkeley, seminars at Stanford University, University of Minnesota, Texas A&M University, University of California at Berkeley, Toulouse School of Economics, Ecole Polytechnique (Paris), CREST and Caen University for useful discussions and comments. Interim Report 2) indicate how much money has been spent to date. How much do you anticipate spending? We have spent $1800 so far, and we anticipate spending the remainder of the budget for the visit of one of the principal collaborators. 3) What remains to be done for this project? When will the project be completed? What remains to be done is to finish the paper and submit and revise and resubmit it to be published. During next year we will work towards that goal. A separate paper will investigate effects on prices of different goods to investigate what are the mechanisms behind the estimated price effects in the first analysis. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have fostered continuing relationships between French institutions and UC campuses. This has been an incredible opportunity for the US researcher to have access to a very detailed data set from the French collaborators, to investigate for the first time the price effects resulting from a retail merger. 5) Will this project result in a publication? (indicate form of publication, if possible.) Yes, as a peer reviewed paper published in a top journal. Annual Report 2013-2014 125 FUNDED PROJECTS BY YEAR 126 Brian A. Barsky, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Jean Sequeira, Informatique, Faculté des Sciences de Luminy, Université Aix-Marseille II Geometric modeling of the cornea using videokeratography Yale M. Braunstein, School of Library and Information Sciences, University of California, Berkeley Anne Mayère, Centre d’Etudes et de Recherche en Sciences de l’Information, ENSSIB, Villeurbanne User fees for government information in France and the United States: Analysis of current policies and practices Eugene D. Commins, Department of Physics, University of California, Berkeley Marie-Anne Bouchiat, Laboratoire Kastler Brossel, CNRS, Paris Violation de la parité dans les atomes: étude de l’interaction électrofaible électron-noyau par des méthodes optiques 1994 David Dornfeld, Engineering Systems Research Center, University of California, Berkeley Serge Tichkiewitch, Centre de Recherche en Automatique de Nancy, Nancy Intégration des procédés de fabrication en conception de produits Larry M. Hyman, Department of Linguistics, University of California, Berkeley Jean-Marie Hombert, Linguistique, Université Lumière Lyon II Language as a key to history Andrew Lange, Department of Physics, University of California, Berkeley François R. Bouchet, Institut d’Astrophysique de Paris, CNRS, Paris Observations and predictions of the cosmological background anisotrophies Steven G. Louie, Department of Physics, University of California, Berkeley gerard Martinez, Physique, Université Joseph Fourier, Grenoble Electron correlation effects in condensed matter system as the newly discovered fullerene-based materials Barbara Romanowicz, Department of Geology and Geophysics, University of California, Berkeley Claude Froidevaux, Ecole Normale Supérieure, Paris Global geophysics Kenneth Ribet, Department of Mathematics, University of California, Berkeley Eva Bayer Fluckiger, Laboratoire de Mathématique, Université de Franche-Comté, Besançon Théorie des nombres Suzanne Scotchmer, School of Public Policy, University of California, Berkeley Jacques-François Thisse, CERAS, Université de Paris I Cumulative innovation and the patent law Charles H. Townes, Department of Physics, University of California, Berkeley Jean Lefèvre, Observatoire de la Côte d’Azur, Nice Etude de la perte de masse des étoiles évoluées Annual Report 2013-2014 127 Walter Alvarez, Department of Geology and Geophysics, University of California, Berkeley Bernard Beaudoin, CGES Sédimentologie, Ecole des Mines de Paris Environmental consequences of the Cretaceous-Tertiary Boundary Event 1995 Daniel S. Chemla, Materials Sciences Division, Lawrence Berkeley National Laboratory Pierre Lefebvre, Groupe d’Etude des Semiconducteurs, Université Montpellier II Optical properties of nanostructures. Low-dimensional excitonic effects Margaret W. Conkey, Department of Anthropology, University of California, Berkeley Valérie Andrieu, Lab. de Botanique Historique et Palynologie, Faculté des Sciences Saint-Jérôme, Marseille Between the caves: explorations into the social geography and paleoenvironments of Late Ice Age peoples of the French Midi-Pyrénées (Ariège/ Haute Garonne), France Gérard Debreu, Department of Economics, University of California, Berkeley Bernard Cornet, CERMSEM, Université de Paris I Mathematical economics Ervin Hafter, Department of Psychology, University of California, Berkeley Anne-Marie Bonnel, CNRS - Laboratoire de Neurosciences Cognitives, Marseille Study of deficits in attention in the diagnosis of onset psychosis Catherine P. Koshland, School of Public Health, University of California, Berkeley sébastien Candel, Laboratoire EM2C de L’ECP et du CNRS, Châtenay-Malabry A strategy to reduce emissions during thermal oxidation of hazardous wastes Laurent Mayali, Robbins Collection, School of Law, University of California, Berkeley Bernard Durand, Institut d’Histoire du Droit, URA 966 CNRS, Université de Montpellier I Délinquance, justice et doctrine pénale ecclésiastique Hiroshi Nikaido, Department of Molecular and Cell Biology, University of California, Berkeley Patrice Courvalin, Institut Pasteur, Paris Role of multi-drug efflux pumps in antibiotic resistance of gram-positive bacteria John Rhodes, Department of Mathematics, University of California, Berkeley Jean-Eric Pin, LITP/IBP, Université de Paris VII Semigroups, groups, automata and formal languages Gene I. Rochlin, Institute of Governmental Studies, University of California, Berkeley Werner Ackermann, Centre de Sociologie des Organisations/CNRS, Paris Cross-national studies of the sociology of organizations: fostering cooperation on methodological coordination and promoting observational inter-comparisons Richard Saykally, Department of Chemistry, University of California, Berkeley Claude leforestier, Laboratoire de Chimie Théorétique, Université de Paris-Sud, Orsay Determination of the intermolecular pair potential for water—the universal biological solvent R. Shen, Department of Physics, University of California, Berkeley E. Courtens, LSMV CC069, Université Montpellier II Non-linear optics in porous materials Pravin Varaiya, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Joseph Sifakis, VERIMAG, Montbonnot Saint-Martin Analysis of hybrid systems: application to the PATH project Loic J.D. Wacquant, Department of Sociology, University of California, Berkeley Pierre Bourdieu, Sociologie, Collège de France, Paris Actualité et Modernité de la Pensée de Marcel Mauss Tim D. White, Department of Anthropology, University of California, Berkeley Raymonde Bonnefille, Laboratoire de Géologie du Quaternaire, CNRS, Marseille Habitat of the earliest human ancestors 128 France-Berkeley Fund Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Joseph Remillieux, Institut de Physique Nucléaire de Lyon et Université Lyon I Production and study of exotic atoms John Canny, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Christian laugier, Institut National de Recherche en Informatique et en Automatique, Grenoble Dynamic simulation for TeleRobotics and medical applications Alexandre J. Chorin, Department of Mathematics, University of California, Berkeley Denis Talay, Institut National de Recherche en Informatique et en Automatique, Sophia Antipolis Les systèmes de particules aléatoires et les applications numériques en mécanique des fluides 1996 Marie-Agnès Deleplanque-Stephens, Nuclear Science Division, Lawrence Berkeley National Laboratory Gilles de France, Centre de Recherches Nucléaires, Université Louis Pasteur, Strasbourg Study of rotating atomic nucleus Susanna Elm, Department of History, University of California, Berkeley Eric Rebillard, Ecole Française de Rome, Rome Boundaries of discourse: Establishing, maintaining and challenging ‘Orthodoxy’ in the history of Christianity Mariane C. Ferme, Department of Anthropology, University of California, Berkeley Jean-Loup Amselle, Centre d’Etudes Africaines, Ecole des Hautes Etudes en Sciences Sociales, Paris Imperialism and identity: Remapping the cultural politics of representation Sylvia Guendelman, School of Public Health, University of California, Berkeley Gérard Bréart, INSERM Unité 149, Paris A world on the move: a comparative look at the birth outcomes of immigrant women in France, Belgium and the United States Russell Jones, Department of Plant Biology, University of California, Berkeley Raoul Ranjeva, Centre de Physiologie Végétale, Université P. Sabatier, Toulouse Isolation and characterization of calcium channels in plants Larry Karp, Department of Agricultural and Resource Economics, University of California, Berkeley Thierry Paul, GREQAM-LEQAM, Université Aix-Marseille II, Les Milles Government policy and labor market imperfections C. Bradley Moore, Department of Chemistry, University of California, Berkeley Pascal Devolder, Université des Sciences et Technologies de Lille, Villeneuve d’Ascq Kinetic investigations of reactive systems by combined laser photolysis/tunable diode absorption spectroscopy and LIF Forrest S. Mozer, Space Sciences Laboratory, University of California, Berkeley Raymond Pottelette, Centre d’Etudes des Environnements Terrestre et Planétaires, Saint-Maur des Fosses Study of acceleration and radiation processes in geospace plasmas Hans georg Ritter, Nuclear Science Division, Lawrence Berkeley National Laboratory Barbara Erazmus, Laboratoire de Physique Subatomique et des Technologies Associées, Nantes Development of tracking methods for high-energy experiments Hans Rudolf Wenk, Department of Geology and Geophysics, University of California, Berkeley Michel Pernet, Laboratoire de Cristallographie - C.N.R.S., Grenoble Texture and anisotropy Annual Report 2013-2014 129 Mina J. Bissell, Life Sciences Division, Lawrence Berkeley National Laboratory Edmond Puvion, Institut de Recherche sur le Cancer, Villejuif Regulation of gene expression by nuclear architectural organization: an ultrastructural analysis combining a unique 3-dimensional cell culture system with novel electron microscopy techniques 1997 Robert Brayton, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Dominique Borrione, Laboratoire TIMA, Université Joseph Fourier, Grenoble Multi-standard verification environment for digital systems design Thomas Broadhurst, Department of Astronomy, University of California, Berkeley James Bartlett, Observatoire Astronomique de Strasbourg, Université Louis Pasteur, Strasbourg Large-scale structure and galaxy formation William Danchi, Space Sciences Laboratory, University of California, Berkeley Jean Gay, Observatoire de la Côte d’Azur, Nice High angular resolution and mass loss of evolved stars Paula Fass, Department of History, University of California, Berkeley Agnes Fine, UFR d’Historia, Université de Toulouse Le Mirail A comparative analysis of ‘new families’ in France and the United States Ralph Freeman, School of Optometry, University of California, Berkeley Yves Fregnac, Institut Alfred Fessard, Gif-sur-Yvette An integrative regulation of functional connectivity in the developing and adult visual cortex Melvin Klein, Structural Biology Division, Lawrence Berkeley National Laboratory Jean-Jacques Girerd, Laboratoire de Chimie Inorganique, Université Paris-Sud, Orsay XAS (Xanes and EXAFS) studies coupled to electro-chemistry of chemical models of the catalytic site of the oxygen evolving center PSII Paolo Mancosu, Department of Philosophy, University of California, Berkeley Hourya Sinaceur, Institut d’Histoire et Philosophie des Sciences et des Techniques, Université de Paris I Bernard Bolzano: Philosophy of logic and mathematics Frank McLarnon, Department of Chemical Engineering, University of California, Berkeley Françoise Argoul, Centre de Recherche Paul Pascal, Pessac Application of advanced optical techniques for probing interfacial electrochemical processes saul Perlmutter, Center for Particle Astrophysics, Lawrence Berkeley National Laboratory Reynald Pain, LPNHE, Universités Paris VI & VII, Paris Measurement of the cosmological parameters Using Type Ia Supernova Richard Saykally, Department of Chemistry, University of California, Berkeley Claude leforestier, Laboratoire Structure Dynamique des Systèmes Moléculaires et Solides, Université Montpellier I The dynamics of a nucleotide base hydration Brian Staskawicz, Department of Plant Biology, University of California, Berkeley Ulla Bonas, Institut des Sciences Végétales, Gif-sur-Yvette Identification and characterization of novel genes for disease resistance in capsicum annum David Stronach, Department of Near Eastern Studies, University of California, Berkeley Frantz Grenet, école Normale Supérieure, Paris Workshop on strategies for joint archaeological excavation and research in Central Asia Michael Watts, Institute of International Studies, University of California, Berkeley Gilles Allaire, UFR d’économie et de Sociologie Rurales, INRA, Castanet-Tolosan Systems and trajectories of innovation: Institutions, technology and conventions in agriculture regulation 130 France-Berkeley Fund Andrew Barshay, Department of History, University of California, Berkeley Jean-François Sabouret, Etudes Japonaises, CNRS, Paris 1968: Events and legacies Jeffrey granett, Department of Entomology, University of California, Davis François Leclant, UFR d’Ecologie animale et de Zoologie agricole, ENSA-INRA, Montpellier Understanding genetic variability of grape phylloxera Mack Kennedy, Center for Isotope Geochemistry, Earth Science Division, LBNL Simon Sheppard, Laboratoire de Sciences de la Terre, Ecole Normale Supérieure de Lyon Origin and role of fluids involved in active faulting 1998 Hendrik Lenstra, Department of Mathematics, University of California, Berkeley Leila Schneps, Laboratoire de Mathématiques, Université de Franche-Comté, Besançon Galois theory Xiaoye Sherry Li, National Energy Research Scientific Computing, Lawrence Berkeley National Laboratory iain Duff, Parallel Algorithms Project, CERFACS, Toulouse Hybrid ordering algorithms for sparse direct and iterative solvers Sharon Marcus, Department of English, University of California, Berkeley Karen Bowie, Ecole d’Architecture de Paris-Val-de-Marne, Charenton-le-Pont Forms of urban life in Paris, 1815-1851 Daniel Neumark, Department of Chemistry, University of California, Berkeley Benoît Soep, Laboratoire de Photophysique Moléculaire, Université de Paris-Sud, Orsay Time-resolved studies of transition state dynamics Hiroshi Nikaido, Department of Molecular and Cell Biology, University of California, Berkeley Patrick Plésiat, Laboratoire de Bactériologie, Faculté de Médecine, Université de Franche-Comté, Besançon Characterization of a new multidrug efflux pump in pseudomonas aeruginosa Gordon Rausser, College of Natural Resources, University of California, Berkeley Patrick Rio, UFR d’Economie et de Sociologie Rurales, INRA, Montpellier Multilateral negotiations over water management in France and California David Robin, Advanced Light Source, Lawrence Berkeley National Laboratory Jasques Laskar, Astronomie et Systèmes Dynamiques, Bureau des Longitudes, CNRS, Paris Application of frequency map analysis to the Advanced Light Source Alistair Sinclair, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Claire Kenyon, LRI, Université de Paris-Sud, Orsay Phase transitions and computational complexity Mark Strovink, Department of Physics, University of California, Berkeley Gregorio Bernardi, LPNHE, Universités de Paris VI et VII Search for supersymmetric decays of the top quark David Wessel, Center for New Music and Audio Technologies, University of California, Berkeley Xavier Rodet, Institut de Recherche et Coordination Acoustique/Musique [IRCAM], Paris Gestural control of musical sound synthesis Annual Report 2013-2014 131 Robert BonDurant, School of Veterinary Medicine, University of California, Davis Francis Fieni, Ecole Nationale Vétérinaire de Nantes Transmission of CAE retrovirus via breeding technologies in dairy goats 1999 Daniel S. Chemla, Materials Sciences Division and Advanced Light Source, Lawrence Berkeley National Laboratory Jérôme Tignon, Laboratoire de Physique de la Matière Condensée, Ecole Normale Supérieure, Paris Spectroscopie optique non linéaire de nanostructures de semiconducteurs Neil Fligstein, Department of Sociology, University of California, Berkeley Rémi Lenoir, Sociologie, Université de Paris I; CSEC-CSE/EHESS, Paris French field theory and American New Institutionalism: Building theoretical bridges for the analysis of contemporary politics and culture Gerson Goldhaber, Supernova Cosmology Project, Lawrence Berkeley National Laboratory Reynald Pain, Universités de Paris VI et VII Measurement of the cosmological parameters using Type 1a Supernovae Patrick V. Kirch, Department of Anthropology, University of California, Berkeley Eric Conte, Université Française du Pacifique, Tahiti Prehistoric Polynesian voyaging and island colonization: New archaeological perspectives Mike Levine, Department of Molecular and Cell Biology, University of California, Berkeley Christian sardet, UMR 643 CNRS, Station Zoologique, Villefranche-sur-Mer Searching for muscle determinants in a simple chordate embryo Krishna K. Niyogi, Department of Plant and Microbial Biology, University of California, Berkeley Michel Havaux, Département d’Ecophysiologie Végétale/ Microbiologie, CEA / Cadarache, Saint-Paul-lez-Durance Role of the xanthophylls in the protection of plants from photo-oxidative damage Nicholas Paige, Department of French, University of California, Berkeley Christian Biet, Institut d’Etudes théâtrales, Université de Paris X, Nanterre The literature of law: judicial and economic culture, 1550-1789 Shankar Sastry, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Christian laugier, Projet SHARP, INRIA Rhône-Alpes, Montbonnot Saint-Martin High-fidelity computer simulations of medical procedures tito serafini, Department of Molecular and Cell Biology, University of California, Berkeley Alain Chédotal, INSERM Unité 106, Paris Neuronal target recognition and synaptogenesis in the mammalian brain Jonathan Shewchuk, Electrical Engineering and Computer Sciences, University of California, Berkeley Marc Daumas, Laboratoire de l’Informatique du Parallélisme, Ecole Normale Supérieure de Lyon Floating-point multiple precision arithmetic for adaptive computation and elementary functions James H. Underwood, Center for X-Ray Optics, Lawrence Berkeley National Laboratory Coryn Frank Hague, Laboratoire de Chimie Physique, Université de Paris VI Magneto-optics of polarized soft X-Rays Maciej Zworski, Department of Mathematics, University of California, Berkeley Frédéric Klopp, Institut Galilée, Université Paris-Nord, Villetaneuse Spectral and scattering theory 132 France-Berkeley Fund Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Joseph Remillieux, Institut de Physique Nucléaire de Lyon Experimental studies of vacuum-assisted photoionization Stanley Berger, Department of Mechanical Engineering, University of California, Berkeley Francis Cassot, INSERM, Toulouse Numerical and experimental simulations of cerebral blood flow for/and magnetic resonance imaging (MRA & MRI) Edward Berry, Physical Biosciences Division, Lawrence Berkeley National Laboratory Jean-Luc Popot, Institut de Biologie Physico-Chimique, Paris Crystallization of cytochrome bc 1/amphipol complexes 2000 Carlos Bustamante, Departments of Physics and Molecular and Cell Biology Malcolm Buckle, Institut Gustave Roussy, Paris RNA polymerase translocation: a comparative study using rapid footprinting, surface plasmon resonance and single molecule methodologies Deborah Hopkins, Engineering Division, Lawrence Berkeley National Laboratory Joëlle Riss, CDGA, Université de Bordeaux I Micromechanics of natural rock fractures under shear stress Carole Meredith, Department of Viticulture and Enology, University of California, Davis Jean-Michel Boursiquot, ENSA, Montpellier DNA profiling and parentage analysis of grape varieties held in the INRA collection at Domaine de Vassal John Radke, Geographic Information Science Center, University of California, Berkeley Didier Josselin, Laboratoire THEMA, Université de Franche-Comté, Besançon A boundary generation system for landscape characterization Richard scheffler, School of Public Health, University of California, Berkeley Christine Huttin, Université de Paris X-Nanterre The growth of private insurance and managed care in France: Insights from the American experience George Smoot, Department of Physics, University of California, Berkeley James Bartlett, Observatoire Midi-Pyrénées, Toulouse Precision cosmology from CMB data processing and analysis techniques William Sullivan, Department of Biology, University of California, Santa Cruz Alain Debec, Université Pierre et Marie Curie, Villefranche-sur-Mer Investigating the paradox of parthenogenesis Norman Terry, Department of Plant and Microbial Biology, University of California, Berkeley Jean-Claude Davidian, ENSA-INRA, Montpellier Mechanisms of selenium uptake, sequestration and resistance in arabidopsis and yeast mutants David Vogel, Haas School of Business, University of California, Berkeley Jabril Bensédrine, Economie et Gestion, Université de Marne-la-Vallée French and American perspectives on genetically-engineered food: Institutional convergence and divergence as sources of cooperation and dispute Wen-hsin Yeh, Department of History, University of California, Berkeley Christian Henriot, Institut d’Asie Orientale, Université Lumière Lyon II Shanghai in images: a historical photographic database (1840-1949) Qiang Zhou, Department of Molecular and Cell Biology, University of California, Berkeley Olivier Bensaude, Ecole Normale Supérieure, Paris Functional analysis of RNA-binding activity of the human positive transcription elongation factor, P-TEFb Alexandra Navrotsky, Department of Chemical Engineering and Materials Science, University of California, Davis Roger Marchand, Laboratoire «Verres et Céramiques,» Université de Rennes I Thermochemistry of a new class of inorganic nitrogen-containing materials Sharon Daniel, Department of Film and Digital Media, University of California, Santa Cruz Karen O’Rourke, UFR d’Arts Plastiques et Sciences de l’Art, Université de Paris I Mapping the database: designing and building interdisciplinary, non-hierarchical, dynamically evolving art/information systems Annual Report 2013-2014 133 Jesús De Loera, Department of Mathematics, University of California, Davis András Sebö, CNRS Laboratoire Leibniz-IMAG, Grenoble Computer algebra methods in graph theory and optimization 2001 Imke de Pater, Department of Astronomy, University of California, Berkeley Renée Prangé, Institut d’Astrophysique Spatiale, Université de Paris XI Monitoring and study of Io’s volcanic activity David Deamer, Department of Chemistry and Biochemistry, University of California, Santa Cruz Marie-Christine Maurel, Institut Jacques Monod, Université de Paris VI Oligomerization of thioglutamic acid in membrane-defined microenvironments Deborah Delmer, Section of Plant Biology, University of California, Davis Herman Höfte, Laboratoire de Biologie, INRA, Versailles The use of arabidopsis mutants to trace the path of carbon into cellulose in plants Mark Franko, Department of Theater Arts, University of California, Santa Cruz Carlo Severi, Laboratoire d’Anthropologie sociale, EHESS, Collège de France Symbolic actions: ritual, dance, theater, art Bronwyn Hall, Department of Economics, University of California, Berkeley Jacques Mairesse, Institut National de la Statistique et des Etudes Economiques [INSEE]-CREST, Malakoff Economics, history and law of intellectual property: proposal for a Franco-American conference Kevin Healy, Bioengineering and Department of Materials Science and Engineering, University of California, Berkeley Véronique Migonney, Institut Galilée, Université de Paris XIII, Villetaneuse Peptide-modified heparin-like copolymers as biomimetic coatings for orthopaedic implants: synthesis, surface characterization, and biological response David Hult, Department of French, University of California, Berkeley Danielle Bohler, Langue et littérature françaises du Moyen Age, Université Michel de Montaigne Bordeaux III La Culture du Livre: naissance et transformations du lecteur depuis la fin du Moyen Age jusqu’au seuil de la modernité Douglas Kellogg, Molecular, Cell and Developmental Biology, University of California, Santa Cruz Robert Arkowitz, CNRS UMR 6543, Centre de Biochimie, Université de Nice G-protein regulation of growth location Tonya Kuhl, Department of Chemical Engineering and Material Science, University of California, Davis Carlos Marques, LDFC-Institut de Physique, Université de Strasbourg Binding dynamics of tethered ligand-receptor interactions Ethan Ligon, Department of Agricultural and Resource Economics, University of California, Berkeley Pierre Dubois, UFR d’Economie et de Sociologie Rurales, INRA, Toulouse Microeconomic theory and empirical studies of intra-household behavior in developing countries Jeffrey long, Department of Chemistry, University of California, Berkeley Patrick Batail, Institut des Matériaux Jean Rouxel, Nantes Synthesis and magnetic properties of Re6-nOsnSe8(n=1-3) cluster-organic radical salts Christos Papadimitriou, Computer Science Division, University of California, Berkeley Evripidis Bampis, Laboratoire de Méthodes Informatiques, Université d’Evry Val d’Essonne MULT-APPROX: multiobjective optimization and approximation Carl Pennypacker, Space Sciences Laboratory, UCB and Lawrence Berkeley National Laboratory Michel Boër, CNRS FRE 2194 Centre d’Etude Spatiale des Rayonnements, Toulouse Developing an Internet-mediated astronomy research/teacher training program for France, U.S. and other nations saul Perlmutter, Physics Division, Lawrence Berkeley National Laboratory Pierre Antilogus, Institut de Physique Nucléaire de Lyon Nearby supernova factory project (software) Richard Saykally, Chemistry, University of California, Berkeley and Lawrence Berkeley National Laboratory Claude Roth, Département d’Immunologie, Institut Pasteur, Paris Investigating the physiology of natural killer cells by nonlinear chemical imaging nanomicroscopy 134 France-Berkeley Fund Hei Sook Sul, Department of Nutritional Sciences and Toxicology, University of California, Berkeley Axel Kahn, Institut Cochin de Génétique Moléculaire, INSERM Unité 129, Paris Regulation of fatty acid synthase promoter by AMP-dependent protein kinase Pravin Varaiya, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Michel Diaz, Laboratoire d’Automatique et d’Analyse des Systèmes-CNRS, Toulouse End to end transport protocols for the new generation internet Annual Report 2013-2014 2001 135 Ronald Amundson, Division of Ecosystem Sciences, University of California, Berkeley Isabelle Basile, CEREGE-Université Aix-Marseille III Le cycle du carbone dans les sols: rôle des interactions matière organique / aluminosilicates pseudo-cristallises 2002 Edmund Campion, Department of Music Composer in Residence, CNMAT Francois Paris, Centre International de Recherche Musical CIRM/CNMAT Collaboration A. Chatterjee, Life Sciences Division, Lawrence Berkeley National Laboratory A. Chetioui, Université Pierre et Marie Curie, GPS Biological consequences of inner-shell ionization events on DNA Eugene Commins, Department of Physics, University of California, Berkeley Francois Combes, LERMA, Observatoire de Paris Supernovae and dust: following the dust from galaxy formation to cosmological parameters Kurt Cuffey, Department of Geography, University of California, Berkeley Francois Vimeux, CR2 Institut Recherche pour le Développement - Lab. Sciences du Climat et de l’Environnement Improved precipitation isotope analyses for climate change studies Agnes Gellen, Department of Philosophy, University of California, Berkeley Elise Domenach, Department of Philosophy, University de Picardie Jules Verne Kant’s trans-Atlantic legacy of skepticism Louise Glass, Plant and Microbial Biology Department, University of California, Berkeley Corrine Clavé, Laboratoire de Génétique Moléculaire des Champignons Comparative analysis of the programmed cell death reaction triggered by nonself recognition genes in two model fungal species John Gunion, Physics Department, University of California, Davis Ulrich Ellwanger, Theoretical Physics Laboratory, University de Paris-Sud Supersymmetric Higgs Bosons at the Large Hadron Collider Larry Hyman, Department of Linguistics, University of California, Berkeley Gerard Phillipson, INALCO Paris, en délégation au Laboratoire Dynamique du Langage Linguistic philogenies in the Bantu domain Jennifer Johnson-Hanks, Department of Demography, University of California, Berkeley Nathalie Picard-Tortorici, THEMA, Université de Cergy-Pontoise Nouveaux regards sur la fécondité en Afrique Occidentale Edward Keller, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley laurent goffard, CNRS Distributed neural control of visual saccades Warren Sack, SIMS, University of California, Berkeley Françoise Detienne, INRIA-Rocquencourt, Projet EIFFEL Social and cognitive analyses of collaborative design for open source Kevan Shokat, Department of Chemistry, University of California, Berkeley Michael Sieweke, Centre d’Immunologie de Marseille Luminy Role of subnuclear localization and complex formation of transcription factors in differentiation Tyler Stovall, Department of History, University of California, Berkeley Michel Giraud, CNRS/Université des Antilles et de la Guyane Strangers at home: Caribbean immigrants in France and the United States Daniel Tataru, Department of Mathematics, University of California, Berkeley Patrick Gerard, Department of Mathematics, Université de Paris-Sud, Orsay Nonlinear Schrödinger equations and geometry Slawek Tulaczyk, Department of Earth Sciences, University of California, Santa Cruz Catherine Ritz, Laboratoire de Glaciologie et Géophysique de l’Environnement Possible near-future breakup of the Ross Ice Shelf and other forms of unstable behavior of the Antarctic Ice Sheet: Evaluating the impact of decreasing ice discharge from the Ross Ice Streams 136 France-Berkeley Fund Sandrine Dutoit, School of Public Health, University of California, Berkeley Jean Daniel Zucker, CNRS-STIC team, University of Paris XIII OBELINKS: Combining machine learning and biostatistics to discover significant obesity related genetic polymorphisms Donald C Rio, Department of Molecular and Cell Biology, University of California, Berkeley Bertrand Seraphin, CNRS-Centre de Génétique Moléculaire In vitro study of the exon-junction complex assembly in Drosophila David H. Raulet, Department of Molecular and Cell Biology, University of California, Berkeley Eric Vivier, Centre d’Immunologie de Marseille-Luminy The role of immune receptors in vivo 2003 Georges F. Smoot, Department of Physics, University of California, Berkeley James g. Barlett, Collège de France, Laboratoire de Physique Corpusculaire et Cosmologie Precision cosmology from CMB analysis Eva Harris, School of Public Health, University of California, Berkeley Chris Mueller, INSERM-CNRS Infection of dermal dendrocytes with clinical isolates of dengue virus Daniel S. Chemla, Department of Physics, University of California, Berkeley Jerome Tignon, Ecole Normale Supérieure, LPMC Condensation des polaritons de microcavité de semiconducteurs Roland Burgmann, Department of Earth and Planetary Science, University of California, Berkeley Edouart Kaminski, Institut de Physique du Globe, Université Paris VII Seismic anisotropy in the San Andreas Shear Zone William A. Lesler, Department of Chemistry, University of California, Berkeley Michel Caffarel, Laboratoire de Chimie Théorique, CNRS-Université Paris VI Quantum Monte Carlo for molecules Barry Sinervo, Department of Ecology and Evolutionary Biology, University of California, Santa Cruz Michael Hochberg, CNRS-Institut des Sciences et de l’Evolution, Université de Montpellier II Potential role of social interactions in the speciation process Sam Krucker, Space Sciences Laboratory, University of California, Berkeley Karl-Ludwig Klein, Observatoire de Paris, Section de Meudon New coordinated investigation of accelerated particles at the Sun and in the Interplanetary Medium Kunxin Luo, Department of Molecular and Cell Biology, University of California, Berkeley Alain Mauviel, INSERM Blocking of fibrosis by Smad co-repressor James Casey, Department of Mechanical Engineering, University of California, Berkeley Gerard Maugin, Laboratoire de Modélisation en Mécanique, Paris VII Application of modern concepts of nonlinear continuum mechanics to some problems of biomechanics: growth, remodeling Filip Filippou, Department of Civil and Environment Engineering, University of California, Berkeley Jacky Mazars, Laboratoires Sols, Solides, Structures, Institut National Polytechnique Grenoble High performance modeling of shear failure of concrete columns under earthquake excitations Patrick V. Kirch, Anthropology Department, University of California, Berkeley Jean-Louis Rallu, Institut National Etudes Démographiques Paris Long-term demographic evolution in French Polynesia: an interdisciplinary approach Sengupta Raja, Department of Civil and Environment Engineering, University of California, Berkeley Stavros Tripakis, Verimag-CNRS Service networks—intelligent middleware for distributed applications Peter Yu, Department of Physics, University of California, Berkeley Adnen Mlayah, Laboratoire de Physique des Solides, CNRS Université Paul Sabatier, Toulouse Optical scattering from quantum dots nanostructures Annual Report 2013-2014 137 Ali Shakouri, Electrical Engineering, University of California, Santa Cruz Stefan Dilhaire, CPMOH-Université Bordeaux 1 Caractérisation optique de micro-réfrigérateurs par des techniques interférométriques et réflectométriques femtosecnodes 2003 138 Claire Kramsch, Department of German, University of California, Berkeley Geneviève Zarate, Institut National des Langues et Civilisations orientales Language, culture and identity in second/foreign language learning and teaching an interdisciplinary workshop Diane Marie Arman, School of Law, University of California, Davis Mireille Delmas-Marty, Collège de France, Unité Mixte de Recherche de Droit Comparé de Paris International criminal justice and common values of humanity France-Berkeley Fund Gerson Goldhaber, Department of Physics, University of California, Berkeley Reynald Pain, LPNHE, Université Paris VI & VII Measuring the cosmic vacuum energy Piedong Yang, Department of Chemistry, University of California, Berkeley François Lagugne-Labarthet, LPCM, UMR5803 CNRS Bordeaux Spectroscopy of one-dimensional semiconductor nanostructures A.R. Flegal, Environmental Toxicology, University of California, Santa Cruz A. Veron, CEREGE, UMR6635, CNRS Université Aix-Marseille III Coral reconstruction of rapid changes in air mass & ocean circulation in the North Atlantic within the past 200 years 2004 Robert Knapp, Department of Classics, University of California, Berkeley Vincent Jolivet, Ecole Française de Rome, CNRS Rome Etruscan sarcophagi from Musarna in the Berkeley Museum Joseph Campos, Institute of Human Development, University of California, Berkeley Marianne Barbu-Roth, LPBD, Ecole pratique des Hautes Etudes, Paris Are newborns programmed to walk on the Earth? Judith Klinman, Department of Chemistry, University of California, Berkeley Marius Réglier, CNRS 7517, Université d’Aix-Marseille 02 activation in metallobiochemistry: probes for the functional copper-oxygen species in the neuroactive enzymes, DbM and PHM Nitash P. Balsara, Department of Chemical Engineering, University of California, Berkeley Carlos Marques UMR CNRS-ULP 7506, Institut de Physique Strasbourg Self-assembly of monodisperse vesicles: answering the challenge by block copolymer design Vittal Yachandra, Physical Biosciences Division, Lawrence Berkeley National Laboratory Sun Un, CNRS URA 2096, CEA Saclay Single Crystal Multifrequency EPR and exafs studies of multinuclear Mn complexes relevant to the oxygen-evolving complex in Photosystem II Bob B. Buchanan, Department of Plant and Microbial Biology, University of California, Berkeley Françoise Montrichard, UMR 1191 INH INRA Université d’Angers Exploring the mechanism of germination in leguminous seeds Brigitta Whaley, Department of Chemistry, University of California, Berkeley Alexandra Viel, UMR 56+26 IRSAMC, Université Toulouse Atomic and molecular probes of superfluids Dominic Massaro, Department of Psychology, University of California, Santa Cruz Yves Laprie, LORIA CNRS UMR 7503, 54600 Villers-les-Nancy Improving the labial coarticulation in talking heads Tonya Kuhl, Department of Chemical Engineering, University of California, Davis Philippe Richetti, CNRS, Centre de Recherche Blaise Pascal, Université Bordeaux Static and dynamic properties of self-assembled surfactant layers and associative polymers Richard Harland, Department of Molecular and Cellular Biology, University of California, Berkeley Anne-Hélène Monsoro-Burq, UMR146, CNRS Institut Curie, Orsay Gene profiling in early neural crest development Dean Toste, Department of Chemistry, University of California, Berkeley Jean-Marc Campagne, ICSN, CNRS Gif-sur-Yvette Synthesis of bioactive polyol natural product by catalytic asymmetric mukaiyama adool and olefin hydration Anne Britt, Plant Biology Department, University of California, Davis Marie-Edith Chaboute, IBMP/CNRS Université Louis Pasteur Strasbourg Plant response to replication stress Annual Report 2013-2014 139 Ehud isacoff, Department Of Molecular and Cell Biology, University of California, Berkeley Serge Charpak, Laboratoire de Neurophysiologie, ESPCI/INSERM Paris Manipulation and detection of olfactory functions 2005 Nilabh Shastri, Department of Molecular and Cell Biology, University of California, Berkeley Philippe Pierre, Centre d’Immunologie de Marseille-Luminy UMR 6102 INSERM CNRS Marseille Cryptic antegenic peptide processing in dendritic cells Paulo J. M. Monteiro, Department of Civil and Environmental Engineering, University of California, Berkeley Olivier P. Coussy, Ecole Nationale Ponts & Chaussées - 6-8 Av. Blaise Pascal, Cité Descartes, Marne-la-Vallée Minimization of the stresses generated by ice formation in concrete Rachel A Segalman, Department of Chemical Engineering, University of California, Berkeley Cyril Brochon, Département de Polymères, Ecole Européenne de Chimie, Strasbourg Nanopatterning and electrical properties of insulated molecular wires Pamela Ronald, Department of Plant Pathology, University of California, Davis Valérie Verdier, Institut de la Recherche pour le Développement, UMR 5096 IRD/CNRS, Perpignan Characterization of rice T-DNA mutants for their reaction to bacterial blight disease using genome expression profiling Dan I. Slobin, Department of Psychology University of California, Berkeley Maarten Lemmens, Université Lille 3, U.F.R. Angellier, Villeneuve d’Ascq Experimental investigations into language typology Randy Schekman, Department of Molecular and Cell Biology, University of California, Berkeley Bruno Antonny, CNRS Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne Architecture of the COPII coat and mechanisms of vesicle formation Jonathan Beecher, Department of History, University of California, Santa Cruz Jean-Claude Zancarini, ENS Lettres & Sciences Humaines, Lyon The reception of social theories in the 19th century in France and the United States Sergey Nuzhdin, Section of Evolution and Ecology, University of California, Davis Pierre Capy, Laboratoire Populations, Génétique et Evolution, Gif-sur-Yvette Genomics of incipient speciation in Drosophila melanogaster Costas Grigoropoulos, Department of Mechanical Engineering, University of California, Berkeley Jean-Jacques greffet, Lab. EM2C, Ecole Centrale, Chatenay-Malabry Nanoscale heat transfer Barbara A. Romanowicz, Berkeley Seismological Laboratory, University of California, Berkeley Jean-Pierre Vilotte, Département de Sismologie Institut de Physique du Globe de Paris Spectral Element Method implementation for regional tomography of the earth’s upper mantle Peter J. Bickel, Department of Statistics, University of California, Berkeley Alexandre Tsybakov, Laboratoire de Probabilités et Modèles Aléatoires, Université Paris 6, CNRS UMR 7599 How can prediction be possible when data are high dimensional? Charles J. Fillmore, Department of Linguistics, University of California, Berkeley Laurent Romary, Lab. Recherche Informatique et Applications, Université Vandoeuvre -les-Nancy Putting semantics into the trees: towards a French FrameNet Robert Tjian, Department of Molecular and Cell Biology, University of California, Berkeley Olivier Bensaude, CNRS UMR 8541-Ecole Normale Supérieure - Régulation de L’Expression Génétique, Paris Imaging of the eukaryotic transcription machinery in living cells John Bowek, Lawrence Berkeley National Laboratory Michael Meyer, Laboratoire d’Interaction du Rayonnement X avec la Matière; Centre Universitaire Paris-Sud, Orsay Fundamental photoionization processes in excited isolated species Beshara Doumani, Department of History, University of California, Berkeley Randi Deguilhem, CNRS, IREMAM-MMSH, Aix-en-Provence Who controlled the Ottoman legal system? Professions and power configurations in the imperial and provincial courts (18th-20th centuries.) 140 France-Berkeley Fund Alessandra Lanzara, Materials Sciences Division, Lawrence Berkeley National Laboratory Matteo D’Astuto, Institut Minéralogie & Physique des Milieux Condensés, Université Pierre & Marie Curie, Paris 6 Electron phonon interaction in new intercalated layered systems Rebecca Heald, Department of Molecular and Cell Biology, University of California, Berkeley Andreas Merdes, CNRS Toulouse In vitro approaches to study muscle morphogenesis Gary Karpen, Department of Genome Biology, Lawrence Berkeley National Laboratory G. Almouzni, Institut Curie, Paris High-resolution analysis of mouse centromeric heterochromatin organization 2006 Barry Eichengreen, Department of Economics, University of California, Berkeley Marc Flandreau, Department of Economics, Institut d’Etudes Politiques de Paris International currencies in theory and history James R. Graham, Department of Astronomy, University of California, Berkeley Garpard Duchêne, Laboratoire d’Astrophysique, Observatoire de Grenoble, Grenoble Studying the properties of protoplanetary disks across wide ranges of stellar ages and masses Diane M. Beckles, Department of Plant Sciences, University of California, Davis Nadia Bertin, Institut National de la Recherche Agronomique, Avignon Analysis of carbon allocation in transgenic tomatoes via molecular and ecophysiological approaches Andrew Chisholm, Department of Molecular and Cell Biology, University of California, Santa Cruz Jonathan Ewbank, Centre d’Immunologie de Marseille-Luminy, Marseille A kinase linking autophagy and innate immunity in C. elegans Peter C. Vollhardt, Department of Chemistry, University of California, Berkeley Corinne Aubert, Université Pierre et Marie Curie, Paris 6 Preparation of diborylcyclohexadienes and their application in the synthesis of complex molecules Samuel S. Mao, Department of Mechanical Engineering, University of California, Berkeley Jin Yu, Laboratoire de Spectrométrie Ionique et Moléculaire, Physics Department, Université Lyon 1 Femtosecond laser ablation and standoff elemental analysis with laser-induced breakdown spectroscopy Martin Banks, Vision Science, University of California, Berkeley Pascal Mamassian, Institut de Psychologie, Université de Paris 5, Boulogne-Billancourt Time course of adjustment in picture viewing Chin-Fu Tsang, Earth Sciences Division, Lawrence Berkeley National Laboratory Yves Gugliemi, Geosciences Azur, Sophia Antipolis Superimposed effects of surface temperature variations and aquifer free-water surface oscillations on rock slope stability—a unique field experiment analyzed by advanced coupled thermo-hydro-mechanical modelling approaches Nelson Max, Department of Computer Science, University of California, Davis, Livermore Fabrice Neyret, Equipe Evasion, INRIA, Saint Ismier Real-time realistic rendering of clouds Marian Feldman, Department of Near Eastern Studies, University of California, Berkeley Michele Casanova, Département Histoire de l’Art, Université de Rennes 2, Haute-Bretagne Luxury goods: production, exchange, and heritage in the Near East during the Bronze and Iron Ages Jose Renau, Computer Engineering, University of California, Santa Cruz Albert Cohen, INRIA, Université Parc Club Orsay, Orsay Thread-level speculation Christos H. Papadimitriou, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Nicolas Sourlas, Département de Physique, Ecole Normale Supérieure Paris Inference in graphical models and multi-user communications: algorithms, complexity, and large system analysis Sharmila Majumdar, Department of Bioengineering, University of California, Berkeley Francoise Peyrin, CREATIS, INSA, Lyon Synchrotron radiation micro computed tomography: analysis of bone quality Annual Report 2013-2014 141 Xixi Zhao, Department of Earth Sciences, University of California, Santa Cruz Mireille Perrin, Laboratoire de Tectonophysique, Université de Montpellier Intensity of the Earth’s magnetic field during the Miocene 2006 142 Junko Yano, Physical Biosciences Division, Lawrence Berkeley National Laboratory Elodie Anxolabehere-Mallart, Institut de Chimie Moléculaire et des Matériaux d’Orsay, Université de Paris-Sud Biomimetic manganese complexes for water oxidation France-Berkeley Fund Michael Jordan, Computer Science Division and Department of Statistics, University of California, Berkeley Francis Bach & Jean-Philippe Vert, Centre de Bioinformatique, Ecole des Mines, Paris Inference and learning in dynamic graphical models, with applications to speech and bio-informatics David Feldheim, Department of Molecular and Developmental Biology, University of California, Santa Cruz Fanny Mann, IBDML, CNRS UMR 6216 Marseille Monitoring the assembly and function of retinal circuits Alexandre Bayen, Department of Civil and Environmental Engineering, University of California, Berkeley Xavier Litrico, CEMAGREF - UMR G-Eau, Montpellier Modeling and data assimilation of semi-automated water distribution canal networks 2007 Jeffrey R. long, Department of Chemistry, University of California, Berkeley Rodolphe Clérac, Centre de Recherche Paul Pascal, UPR CNRS 8641, Pessac Photomagnetic metal-cyanide clusters Maria Schonbek, Department of Mathematics, University of California, Santa Cruz Dragos iftimie, Institut Camille Jordan, Université Lyon 1, Villeurbanne Asymptotic behavior for the quasi-geostrophic system and the Euler equations Maciej Zworski, Department of Mathematics, University of California, Berkeley Nicolas Burq, Département de Mathématiques, Université Paris Sud, Orsay Mathematical aspects of semiclassical approximation Brian A. Catlos, Department of History, University of California, Santa Cruz Damien Coulon, UFR des Sciences Historiques, Université Marc-Bloch, Strasbourg Inter-confessional relations and trade in the Medieval Mediterranean Richard M. Allen, Department of Earth and Planetary Science, University of California, Berkeley Nikolai Shapiro, Département de Sismologie, Institut de Physique du Globe de Paris, Paris Seismic tremor: a new window to monitor seismic/aseismic coupling at depth and improve earthquake forecasting Hitoshi Murayama, Department of Physics, University of California, Berkeley Emilian Dudas, Ecole Polytechnique, Palaiseau Electroweak symmetry breaking in the LHC Era El Karoui Nouredine, Department of Statistics, University of California, Berkeley Touzi Nizar & El Karoui Nicole, Centre de Mathématiques Appliquées, Ecole Polytechnique, Palaiseau Random matrix theory and mathematical finance George Roderick, Department of Environmental Science, Policy and Management, University of California, Berkeley Maria Navajas, INRA, Centre de Biologie et Gestion des Populations, Montferrier-sur-Lez Invasive insects and mites of Mediterranean climates Kristin scott, Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley Frederic Marion-Poll, INRA, Physiologie de l’Insecte: Signalisation et Communication, Versailles Diversity of bitter tastes in Drosophila Xiaoye Sherry Li, Lawrence Berkeley National Laboratory iain s. Duff, CERFACS, Parallel Algorithms Project, Toulouse Scalable sparse linear equation solvers on emerging petascale computers Warren Pickett, Department of Physics, University of California, Davis Mébarek Alouani, Institut de Physique et Chimie des Matériaux, Université Louis Pasteur, Strasbourg Charge mismatch and magnetism at interfaces Bruce E. Cain, Institute of Governmental Studies, University of California, Berkeley Frédérick Douzet, Institut Français de Géopolitique, Université de Paris 8, Saint Denis Immigration, segregation and urban tension in France and California Ann Banfield, College of Letters and Science, University of California, Berkeley Gilles Philippe, Université Stendhal, Grenoble Linguistics and the language arts: developing new research programs Annual Report 2013-2014 143 Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Hamed Merdji, Commissariat à l’Energie Atomique, Centre d’Etude de Saclay, Gif-sur-Yvette Development of high intensity high harmonic system for studies of non-linear X-ray optics 2007 Qing-Zhu Yin, Department of Geology, University of California, Davis Philippe Gillet, Laboratoire des Sciences de la Terre, Ecole Normale Supérieure, Lyon Davis-Lyon joint investigation of non-traditional stable isotope systematics in the early solar system materials Richard Kern, French Department, University of California, Berkeley Christine Develotte, Ecole Normale Supérieure, Lettres et Sciences Humaines, Lyon Rethinking language teaching in the digital age: French and American perspectives on technology and pedagogy Alison M. Berry, Department of Plant Sciences, University of California, Davis Philippe Normand, CNRS- UMR 5557 Ecologie Microbienne, Villeurbanne Global computational approaches to discovery of microbial gene function and evolution: phylogenomic comparison of two plantassociated Actinobacteria, the thermotolerant biomass-degrader Acidothermus, and the symbiotic nitrogen-fixer Frankia 144 France-Berkeley Fund Louise Glass, Department of Plant and Microbial Biology, University of California, Berkeley Mathieu Paoletti, Laboratoire de Génétique Moléculaire des Champignons, Université Victor Segalen Bordeaux 2 Role of the HET domain in Fungal Nonself Recognition William J. Jagust, Deptartments of Public Health and Neuroscience, UCB and Lawrence Berkeley National Laboratory Michel Isingrini, Université François Rabelais, Centre de Recherche sur la Cognition, Tours Brain basis of metamemory in aging Steven R. Beissinger, Department of Environmental Science, Policy and Management, University of California, Berkeley Jean-Dominique Lebreton, Centre d’Ecologie Fonctionnelle et Evolutive, CNRS UMR 5175, Montpellier Integrated approach for population viability analyses with limited data 2008 George Smoot, Department of Physics, University of California, Berkeley James g. Bartlett, Département de Physique, Université Paris 7 Denis-Diderot, Paris Empowering the CMB: Measuring power spectra from the Planck mission Judith P. Klinman, Departments of Chemistry & Molecular and Cell Biology, University of California, Berkeley Nicolas Mano, CRPP-UPR 8641, Pessac A miniature membraneless biofuel cell Philip Marcus, Department of Mechanical Engineering, University of California, Berkeley Patrice Le Gal, Institut de Recherche sur les Phénomènes Hors Equilibre, Université de Provence, Marseille Numerical simulations versus experiments on inertial-gravity waves Alexandra Navrotsky, NEAT-ORU and Thermochemistry Facility, University of California, Davis Christophe Drouet and Sophie Guillemet, CIRIMAT, UMR CNRS 5085, INSIACET, Toulouse A thermodynamic approach for the understanding of nanomaterials properties Jere H. Lipps, Museum of Paleontology, University of California, Berkeley Marie-Thérèse Vénec-Peyré, Département Histoire de la Terre, Université de Paris 6, Paris Effect of pollution on foraminifera William A. Lester, Department of Chemistry, University of California, Berkeley Roland Assaf, Laboratoire de Chimie Théorique, Université Pierre et Marie Curie, Ivry sur Seine Development of size-independent estimators for quantum Monte Carlo forces Niek Veldhuis, Department of Near Eastern Studies, University of California, Berkeley Francis Joannès, Département d’Histoire, Université de Paris 1 Panthéon-Sorbonne, Paris Hellenistic Babylonia: Texts, iconography & names George Brooks, Department of Integrative Biology, University of California, Berkeley Laurent Messonnier, Lab. of Exercise Physiology and Physiopathology, Université de Savoie, Le Bourget du Lac Effects of endurance training on glucose and lactate metabolism during exercise and recovery in men and women—advancing our knowledge and methods of investigation Juan F. Medrano, Department of Animal Science, University of California, Davis Patrice Martin, Institut National de la Recherche Agronomique, Jouy-en-Josas Contribution of genomics to the understanding of milk fat composition using gene expression profiling of mammary epithelial cells isolated from milk and microdissected biopsies Stefano Varesse, Department of Native American Studies, University of California, Davis Philippe Descola, Laboratoire d’Anthropologie Sociale, Collège de France, Paris All our relatives: indigenous cosmocentric epistemologies in dialogue Philip Filippou, Department of Civil and Environmental Engineering, University of California, Berkeley Jacky Mazars, Institut Polytechnique de Grenoble, Grenoble High performance modeling of 3D soil-structure interaction under earthquake excitation Kurt Cuffey, Department of Geography, University of California, Berkeley Peter Van Der Beek, Observatoire des Sciences de l’Univers de Grenoble, Grenoble Relief development in the Western Alps (France, Switzerland) in response to quaternary glaciations assessed through high-resolution 4He/3He/He thermochronology Annual Report 2013-2014 145 Edgar Knobloch, Department of Physics, University of California, Berkeley Alain Bergeon, IMFT, UMR CNRS 5502, Université Paul-Sabatier, Toulouse Localized structures in driven dissipative flows 2008 Larry Hyman, Department of Linguistics, University of California, Berkeley Jean-Marie Hombert, Dynamique du Langage, Institut des Sciences de l’Homme, Lyon Towards a re-evaluation of the history of the peopling and languages of Sub-Saharan Africa saul Perlmutter, Lawrence Berkeley National Laboratory, Berkeley Gérard Smadja, Institut de Physique Nucléaire de Lyon, Villeurbanne The nearby supernova factory Robert Knight, Helen Wills Neuroscience Institute, University of California, Berkeley Olivier Bertrand, INSERM U821, Centre Hospitalier Le Vinatier, Bron Spatio-temporal organization of cortical oscillatory activities in human audition Bob B. Buchanan, Department of Plant and Microbial Biology, University of California, Berkeley J.-Ph. Reichheld, LGDP UMR CNRS-IRD-UPVD 5096, Université de Perpignan, Perpignan The next step in the identification of thioredoxin target proteins: in vivo characterization with mutants Ravi Rajan & Deborah Letourneau, Department of Environmental Studies, University of California, Santa Cruz Christophe Bonneuil, Centre Koyré d’Histoire des Sciences et des techniques-MNHN CP 25, Paris Mobilizing science for public policy on ecological risks of genetically engineered organisms Christine Hastorf, Department of Anthropology, University of California, Berkeley Gilles Touchais, Département d’Archéologie et Histoire de l’Art, Université de Paris 1 Panthéon- Sorbonne, Paris Food archaeology in Argolid (Greece): Cross-correlation between isotopic analysis and macroscopic observation of the dental remains Irfan Siddiqi, Quantum Nanoelectronics Laboratory, Physics Department, University of California, Berkeley Wolfgang Wernsdorfer, Institut Néel, Nanosciences Department, CNRS, Grenoble Microwave nanomagnetometry of single molecules, towards single spin measurement and control Karlene Roberts, Haas School of Business, University of California, Berkeley Erik Hollnagel, Ecole National Supérieure des Mines de Paris, Sophia-Antipolis Research in catastrophic risk management—finally, the twain shall meet 146 France-Berkeley Fund Pascale Garaud, Baskin School of Engineering, University of California, Santa Cruz Michel Rieutord, Laboratoire d’Astrophysique, Observatoire Midi Pyrénées Toulouse Proposal to support an international summer program in astrophysical modeling Nobuhiko P. Kobayashi, Electrical Engineering, Jack Baskin School of Engineering, UC Santa Cruz Natalio Mingo, LITEN, CEA-Grenoble Collaborative research on “nanoparticle embedded in alloy” thermoelectric materials and devices grown by MOCVD Richard H. Kramer, Molecular and Cell Biology Department, University of California, Berkeley Alexandre Specht, Départementde Chimie Bioorganique Université Louis Pasteur, Strasbourg New two-photon caged neurotransmitters for the photocontrol of neuronal activity and physiology 2009 Richard grotjahn & susan Ustin, Department of Land, Air and Water Resources, University of California, Davis Fabio D’Andrea, Laboratoire de Météorologie Dynamique, Ecole Normale Supérieure, Paris Calibration and mapping of satellite skin temperatures by surface station data with evaluation of WRF guidance for extreme heat waves Peter S. Nico, Earth Sciences Division, Lawrence Berkeley National Laboratory Delphine Derrien, Laboratoire Biogéochimie des Ecosystèmes Forestiers, INRA Nancy Do mineral surfaces stabilize organic matter in soil? 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Integrating transcriptional networks and chromatin-based mechanisms involved in the control of cell differentiation in the model plant Arabidopsis thaliana Zahid Hussain, Advanced Light Source, Lawrence Berkeley National Laboratory Marino Marsi, Laboratoire de Physique des Solides – Université Paris-Sud, Paris New spectroscopic approaches for the study of strongly correlated materials Johan Leveau, Department of Plant Pathology, University of California, Davis Pascale Frey-Klett, Institut National de la Recherche Agronomique, Champenoux Impact of bacterial-fungal interactions on soil evolution, fertility, and vegetation Vittal Yachandra, Physical Biosciences Division, Lawrence Berkeley National Laboratory Pieter Glatzel, Installation Européenne de Rayonnement Synchrotron, Grenoble Ligands of manganese complexes relevant to photosynthetic water oxidation: direct detection using X-ray emission spectroscopy Artyom Kopp, Department Of Ecology and Evolution, University of California, Davis Nicolas Gompel, Institut de Biologie du Développement de Marseille-Luminy, Marseille Developing genetic tools for new model species of Drosophila Robert littlejohn, Physics, University of California, Berkeley Carlo Rovelli, Centre de Physique Théorique, Luminy, Marseille Semiclassical studies of spin networks, Wigner $3nj$- symbols, and quantum gravity Rosemary Gillespie, Environmental Science, Policy, and Management, University of California, Berkeley Christophe Thébaud, Sciences de la Vie et de la Terre, Université Paul Sabatier, Toulouse Community assembly on islands: role of random versus deterministic effects Adrian T. Lee, Department of Physics, University of California, Berkeley Radoslaw Stompor, Laboratoire Astroparticule et Cosmologie, Université Paris 7 Simulations and data analysis of the initial data set of a next generation CMB B-mode polarization experiment: PolarBeaR Annual Report 2013-2014 147 Alan Weinstein, Department of Mathematics, University of California, Berkeley Pierre Schapira, Institut de Mathématiques de Jussieu, Université Paris VI Categorical tools in geometry and in mathematical physics 2009 Robert Kostecki, Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory Christian Julien, Institut des Nanosciences, Université Pierre et Marie Curie – Paris 6 Electrochemical energy storage research—advanced cathode materials for Li-ion battery systems Charles Altieri, English Department, University of California, Berkeley Isabelle Alfandary & Axel Nesme, Département d’Etudes du Monde Anglophone, Université Lumière-Lyon 2 Transatlantic transactions: French theory and twentieth century American poetry Margaret Conkey, Anthropology, University of California, Berkeley Sébastein Lacombe, Université de Toulouse-le Mirail, Toulouse Open air paleolithic occupations on the north slope of the Central Pyrénées: inventory and analysis of a rare and significant collection of prehistoric artifacts Ronnie Lipschutz, Department of Politics, University of California, Santa Cruz Béatrice Hibou, Centre d’études et de recherche internationales, Sciences Po, Paris The public-private hybridization of the 21st century state sofia Berto Villas-Boas, Agricultural and Resource Economics, University of California, Berkeley Céline Bonnet and Pierre Dubois, GREMAQ, Université de Toulouse Non linear wholesale pricing and retail pass-through: evidence from counterfactual experiments AnnaLee Saxenian, School of Information, University of California, Berkeley Hervé Dumez, Centre de Recherche en Gestion, Ecole Polytechnique, Paris Making a mark: early French trademarking practice and its long-term influence 148 France-Berkeley Fund Wolf-Dietrich Heyer, Department of Microbiology, University of California, Davis Xavier Veaute, CEA, Fontenay aux Roses Fonctions des paralogues de Rad51 dans la recombinaison homologue Keith Johnson, Department of Linguistics, University of California, Berkeley Elsa Spinelli, Laboratoire de Psychologie et NeuroCognition, Université Pierre Mendès France, Grenoble 2 Variability and lexical representations Paulo J. M. Monteiro & Roy W. Carlson, Dept. of Civil & Env. Engineering, University of California, Berkeley Pierre Levitz, Laboratoire de Physique de la Matière Condensée, Ecole Polytechnique, Palaiseau Characterization of the nanostructure of calcium silicate hydrates 2010 Bozidar Stojadinovic, Department of Civil and Environmental Engineering, University of California, Berkeley Adnan Ibrahimbegovic, Department of Civil Engineering, Ecole Normale Supérieure de Cachan, Cachan Multi-scale hybrid modeling of failure mechanisms in civil structures under extreme-event loads Mark van der Laan, Group in Biostatistics, University of California, Berkeley Antoine Chambaz, Laboratoire MAP5,Université Paris Descartes Development of causal inference methodology and its application to medical and epidemiological research in France? 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O’Brien, EECS, Computer Science Division, University of California, Berkeley Marie-Paule Cani, INRIA, Grenoble Institute of Technology Real-time simulation methods for interactive surgical simulation and planning John Radke, Landscape Architecture and Environmental Planning, University of California, Berkeley Frédéric Liébault, Cemagref Groupement de Grenoble, Saint-Martin-d’Hères Analysis of historic river corridor response to landscape change and application to river management principles in California and France Nancy Lee Peluso, Department of Environmental Science, Policy and Management, University of California, Berkeley Gabrielle Bouleau, Cemagref, UMR G-EAU, Montpellier Risk societies and governance in Mediterranean climate deltas flood-prone waterscapes Annual Report 2013-2014 149 Kristofer S.J. Pister, College of Engineering, University of California, Berkeley David Simplot-Ryl, INRIA POPS, Université de Lille Implementation and extensive performance evaluation of future standards for wireless sensor networks 2010 Steven Glaser, Department of Civil and Environmental, Engineering University of California, Berkeley Térence Bayen, Center of Mathematic, Université de Montpellier 2 Modeling absolute displacements of the human body to quantify diagnoses neuropathology Thomas Jue, Department of Biochemistry and Molecular Medicine, University of California, Davis David Bendahan, Centre de Résonance Magnétique Biologique et Médicale, Faculté de Médecine de la Timone, Marseille Determination of metabolic transients during a muscle contraction using hyperpolarized 13C, 31P and 1H magnetic resonance spectroscopy Sharman D. O’Neill, Department of Plant Biology, College of Biological Sciences, University of California, Davis Pascale Besse, Univ. de la Réunion, Peuplements Végétaux & Bioagresseurs en Milieu Tropical, La Réunion The France-UC Vanilla Consortium: an international collaboration for genomic research and germplasm conservation for crop improvement of vanilla planifolia David Wessel, CNMAT, University of California, Berkeley Yann Orlarey, GRAME - Centre National de Création Musicale, Lyon Parallelism in interactive real-time signal processing with FAUST and OSC 150 France-Berkeley Fund Carla Shapreau, School of Law, University of California, Berkeley Florence Gétreau, Institut de recherche sur le Patrimoine Musical The loss of French musical property during World War II, post-war repatriations, restitutions, and 21st century ramifications Kenneth Downing, Life Sciences Division, Lawrence Berkeley National Laboratory Manfred Heinlein, Institut de Biologie Moléculaire des Plantes, Strasbourg Structural and functional analysis of the Tobacco mosaic virus movement protein:tubulin complex Nikolaos Papazarkadas, Department of Classics, University of California, Berkeley Denis Knoepfler, Collège de France, Paris The epigraphy and history of Boeotia: new finds, new developments 2011 Marios Panagiotou, Civil and Environmental Engineering, University of California, Berkeley Stéphane Grange, Université Joseph Fourier, Grenoble I High performance modeling of seismic soil foundation structure interaction in tall buildings Dietmar Kueltz, Department of Animal Science, University of California, Davis Jean-Herve Lignot, Université Montpellier 2 Parallel evolution of osmoregulatory mechanisms in fish Dmitry Budker, Department of Physics, University of California, Berkeley Jean-François Roch, Ecole Normale Supérieure de Cachan Magnetometry with color centers in diamond Wim Leemans, Lawrence Berkeley National Laboratory Philippe Martin, CEA Saclay Electron acceleration and relativistic optics in the ultra-high-intensity regime Michael A. Lieberman, Electrical Engineering and Computer Sciences, University of California, Berkeley Pascal Chabert, Ecole Polytechnique, Palaiseau Global model of radiofrequency atmospheric pressure plasmas used for biomedical applications Trent Northen, Life Sciences Division, Lawrence Berkeley National Laboratory Marion Leclerc, Microbiologie-Institut National de la Recherche Agronomique In vitro and in vivo metabolic interaction in a simplified human gut microbiome Michael Levine, Department of Molecular and Cellular Biology, University of California, Berkeley Krzysztof Jagla, Université de Clermont Transcriptional regulation of cell fate decisions during Drosophila cardiovascular development Steven Raphael, Goldman School of Public Policy, University of California, Berkeley Roberto galbiati, Département d’Economie, Sciences Po Paris The emergence of the economic criminologist Eva Harris, School of Public Health, University of California, Berkeley Bruno Canard, Université de la Méditerranée Aix-Marseille The Role of NS3 and NS5 in Dengue Viral Fitness Jack Citrin, Governmental Studies, University of California, Berkeley Frédérick Douzet, Institut Français de Géopolitique, Université Paris 8 Urban Frontier in the age of globalization: a comparative study of France and California Diane M Beckles, Plant Sciences, University of California, Davis Maria Cecilia Arias, Université des Sciences et Technologies de Lille Molecular evolution of starch transcriptional networks in plants Sandrine Dudoit, Division of Biostatistics, University of California, Berkeley Jean-Philippe Vert, Centre for Computational Biology, Mines Paris Tech Statistical methods for the joint analysis of high-throughput transcription and genotype data Nicolas Barrière, Space Sciences Laboratory, University of California, Berkeley Pierre Bastie, LSP, Saint Martin d’Hères High-quality heavy metal crystals study for the realization of an astronomical gamma-ray telescope Annual Report 2013-2014 151 Darcy Grimaldo Grigsby, History of Art, University of California, Berkeley Anne Lafont, Institut national d’histoire de l’art, Paris The Artifice of Color: Representation of Blacks in the French visual arts from the Black Code (1682) to the recognition of the Republic of Haiti (1825) 2011 Ian Faloona, Department of Land, Air, and Water Resources, University of California, Davis Marie Lothon, Université de Toulouse A study of the late afternoon transition in the atmospheric boundary layer Alexandre J. Chorin, Department of Mathematics, University of California, Berkeley Yvon Maday, Université Pierre et Marie Curie, Paris Reduced basis method for the simulation of coupled QM/continuum solvation models Theodore A. Slaman, Department of Mathematics, University of California, Berkeley Laurent Bienvenu, Université Paris Diderot Effective randomness for non-uniform measures Robert Tjian, Department of Molecular and Cellular Biology, University of California, Berkeley Xavier Darzacq, Institut de Biologie de l’Ecole Normale Supérieure, Paris Spatiotemporal dynamics of single transcription factors in eukaryotic cells David L. Shuster, Department of Earth and Planetary Science, University of California, Berkeley Jean Braun, Institut des Sciences de la Terre (ISTerre), Université de Grenoble Catastrophic gorge incision (Skagit River Gorge) induced by glacial lake overspill assessed through high-resolution 4He/3He thermochronology Lawrence Rosenthal, Center for the Comparative Study of Right-Wing Movements, University of California, Berkeley Eric Darras, Institut d’Etudes Politiques de Toulouse Anger in politics: understanding the emergence of the Tea Party movement 152 France-Berkeley Fund David Chandler, Department of Chemistry, University of California, Berkeley Benjamin Rotenberg, Chimie, Université Pierre et Marie Curie, Paris Optimizing self-assembly of complex colloidal systems using Transition Path Sampling Ehud isacoff, Department of Molecular and Cell Biology, University of California, Berkeley Nicole Ropert, Laboratoire de Neurophysiologie et Nouvelles Microscopies, Université Paris Descartes, Paris Optogenetic probing of the mechanisms and functions of gliotransmission Steven G. Louie, Department of Physics, University of California, Berkeley gérard Martinez, Laboratoire National des Champs Magnétiques, CNRS Grenoble Joint experimental and theoretical study of electron-electron and electron-phonon interactions in graphene-based compounds and topological insulators with magneto-optical spectroscopy 2012 Sanjay Kumar, Department of Bioengineering, University of California, Berkeley Manuel Thery, Institut de Recherche en Technologies et Sciences pour le Vivant, CEA, Grenoble Engineering and dissecting the micro-architecture of actomyosin stress fibers Marla Feller, Department of Molecular and Cell Biology, University of California, Berkeley David DiGregorio, Institut Pasteur, Centre National de la Recherche Scientifique, Paris Dendritic processing of synaptic input in retinal interneurons geoffrey W. Marcy, Department of Astronomy, University of California, Berkeley Guillaume Hébrard, Institut d’Astrophysique de Paris / Observatoire de Haute-Provence Combining French and American telescopes to characterize exoplanets Alejandro Aguilar, Advanced Light Source, Lawrence Berkeley National Laboratory Jean-Marc Bizau, Institut des Sciences Moléculaires d’Orsay, Université Paris-Sud First absolute single-photon double photoionization cross section measurements of fundamental 2-electron negative ion: HAlexandre Bayen, Center for Information Technology and Research in the Interest of Society, University of California, Berkeley Paola goatin, INRIA Sophia Antipolis—Méditerranée Optimal traffic flow management with GPS enabled smartphones John Taylor, Department of Plant and Microbial Biology, University of California, Berkeley tatiana giraud, Département Génétique et Ecologie Evolutives, Université de Paris-Sud Genomics of ecological divergence in the fungal species Neurospora discreta Kunxin Luo, Department of Molecular and Cell Biology, University of California, Berkeley Delphine Javelaud, INSERM U1021, Institut Curie, Paris Hippo signaling and Ski in human melanoma development Daniel Fletcher, Department of Bioengineering and Biophysics, University of California, Berkeley Patricia Bassereau, Laboratoire PhysicoChimie Curie, Institut Curie, Paris Mechanical induction of transcellular tunnels Jeremy W. Thorner, Department of Molecular and Cell Biology, University of California, Berkeley Robert A. Arkowitz, CNRS UMR7277 /INSERM UMR1091, Université de Nice—Sophia Antipolis Requirements, molecular roles and distribution of membrane phosphoinositides in yeast external signal-dependent polarized growth Jack L. Gallant, Department of Psychology, University of California, Berkeley Bertrand Thirion, Neurospin, INRIA France Improving fMRI by using anatomical data to constrain functional models Bo Liu, Department of Plant Biology, University of California, Davis David Bouchez, Institut Jean-Pierre Bourgin Uncovering an interactive protein network that regulates microtubule nucleation and organization for plant cell growth Beverly Crawford, Department of Political Science, University of California, Berkeley Denis Rolland, Institut d’Etudes Politiques, Université de Strasbourg Civil society formation in political transitions: the evolution of culture and identity in Latin America, Eastern Europe, and Maghreb/ Machrek 1980-2011 Véronique Munoz-Darde, Department of Philosophy, University of California, Berkeley Lue Foisneau, L’Ecole des Hautes Etudes en Sciences Sociales, Paris A Theory of Justice 40 years on Annual Report 2013-2014 153 Michael A. Rogawski, Department of Neurology, School of Medicine, University of California, Davis Jean-Pierre Mothet, Centre de Recherche en Neurobiologie et Neurophysiologie, Université Aix-Marseille Role of D-serine in migraine 2012 Jeffrey Ross-ibarra, Department of Plant Sciences, University of California, Davis Maud Tenaillon, UMR 8120 de Génétique Végétale, INRA / Université Paris XI / CNRS / INA PG Does domestication affect recombination: a pilot study in maize Jitendra Malik, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Zaid Harchaoui & Cordelia Schmid, Laboratoire Jean Kuntzmann, LEAR, INRIA Grenoble Large-scale learning for image and video interpretation Stephen R. Leone, Departments of Chemistry and Physics, University of California, Berkeley Ian R. Sims, Institut de Physique de Rennes, Université de Rennes 1 Direct measurements of reaction pathways for interstellar and planetary low temperature chemistry Igor V. Grigoriev, Doe Joint Genome Institute, Lawrence Berkeley National Laboratory Francis M. Martin, Institut National de la Recherche Agronomique, Université de Lorraine, Nancy Uncovering evolutionary origins and mechanisms of mycorrhizal symbiosis and wood decay machinery in forest ecosystems by comparative genomics Steven Conolly, Department of Bioengineering, University of California, Berkeley Xavier Maître, Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS, Université Paris-Sud Aerosol deposition in the airways with phase-imaging tools for inhaled drug delivery Charles Marshall, Department of Integrative Biology, UCB / University of California Museum of Paleontology Hélène Morlon, Centre de Mathématiques Appliquées de l’Ecole Polytechnique, Palaiseau Integrating molecular phylogenies and the fossil record Kenneth Ribet, Department of Mathematics, University of California, Berkeley Ariane Mézard, Laboratoire de Mathématiques de Versailles, Université de Versailles Saint-Quentin Summer 2013 workshop on new geometric techniques in number theory Stephanie Lee Mudge, Department of Sociology, University of California, Davis Antoine Vauchez, CNRS—Centre Européen de Sociologie et de Science Politique de l’Université, Université Paris 1 When theory matters: law, economics, and the scholarly production of “Europe”, 1990-2010 Vern Paxson, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Renata CruzTeixeira, Laboratoire d’Informatique de Paris 6 Understanding user perspectives of internet performance 154 France-Berkeley Fund Sophia B. Villas-Boas, Department of Agricultural and Resource Economics, University of California, Berkeley Claire Chambolle, INRA (Institut National de la Recherche Agronomique), Ivry sur Seine The impact of retail mergers on food prices: evidence from France Barbara Romanowicz, Department of Earth and Planetary Science, University of California, Berkeley Yann Capdeville, Laboratoire de Planétologie et Géodynamique de Nantes Probabilistic interpretation of seismic tomographic models Déborah Blocker, Department of French, University of California, Berkeley Anne Piéjus, Institut de Recherches sur le patrimoine musical en France New tools and stakes for the study of language and culture in early modern French periodicals: the case of the Mercure Galant 2013 Nicholas Paige, Department of French, University of California, Berkeley Guillaume Peureux, Paris 10-Nanterre The “I” before “the Self”: Non-modern uses of the first person in Renaissance and Classical France Wayne Marcus Getz, Department of Environmental Sciences, Policy and Management, University of California, Berkeley Pierre Magal, Institut de Mathématiques de Bordeaux, Université Bordeaux Segalen Individual-based, structurally and demographically-detailed epidemic models Susan J. Muller, Department of Chemical Engineering, University of California, Berkeley Thibaut Divoux, Centre de Recherche Paul Pascal (CNRS - UPR 8641) Testing a generalized stability criterion for viscoelastic flows Elizabeth Moxon, Advanced Light Source, Lawrence Berkeley National Laboratory Claus Habfast, European Synchrotron Research Facility An international comparative study of best practices in providing high school student access to synchrotrons to conduct outreach experiments Jason Corburn, School of Public Health and Department of City and Regional Planning, University of California, Berkeley Gérard Salem, Université Paris Ouest, UFR SSA Global urban health: Collaborative research for a new science of the city Lauren Williams, Department of Mathematics, University of California, Berkeley Sylvie Corteel, CNRS et Universite Paris Diderot Tableaux combinatorics Suzanne Guerlac, Department of French, University of California, Berkeley Jean-Pierre Montier, Département de Lettres, Université Rennes 2 Towards a coherently structured development of photoliterary research Pablo Ross, Department of Animal Science, University of California, Davis Hélène Jammes, Unité Biologie du Développement et Reproduction, INRA A systems biology approach to understand parental specific contributions to embryo and placenta development John P. Huelsenbeck, Department of Integrative Biology, University of California, Berkeley Vincent Daubin, Laboratoire de Biométrie et Biologie Evolutive, Université Lyon 1 Claude Bernard User-friendly phylogenomics: Bayesian simultaneous reconstruction of gene trees and species trees Daniela Kaufer, Department of Integrative Biology and Helen Wills Neuroscience Institute, University of California, Berkeley Francois Tronche, Gene Regulation and Adaptive Behaviors team, CNRS Dissecting GR gene function in adult brain stem cells Winfried Kudszus, Department of German, University of California, Berkeley Richard Trim, Faculté des Arts, Lettres, Langues et Sciences Humaines, Aix-Marseille Université Metaphor in the political debate of austerity programs Robert T. Knight, Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley Fanny Meunier, Centre de Recherche en Neurosciences de Lyon Brain dynamics of compensatory mechanisms for lexical selection in overt speech production after left prefrontal damage Nicolai Reshetikhin, Department of Mathematics, University of California, Berkeley Christian Blanchet, Institut de Mathématiques de Jussieu, Université Paris Diderot Categorification of quantum invariants of 3-dimensional manifolds Annual Report 2013-2014 155 Susan G. Miller, Department of History, University of California, Davis Jocelyne Dakhlia, L’École des Hautes Études en Sciences Sociales, Centre de Recherches Historiques Networking for independence: The Moroccan nationalist movement’s global campaign against French colonialism 2013 geoff Bower, Department of Astronomy, University of California, Berkeley Gilles Thereau, Station de Radioastronomie de Nançay Observatoire de Paris French / American collaboration for radio investigations of time-variable astrophysical phenomena Lance J. Kriegsfeld, Department of Psychology, University of California, Berkeley Matthieu Keller, CNRS, Équipe Neuroendocrinology des Interactions et Comportements Sexuels Neuroendocrine gating of olfactory perceptual processing John Harvey, Department of Civil and Environmental Engineering, University of California, Davis Agnès Jullien, IFFSTAR Comparison of use phase methodology and recycling approach for pavement life cycle assessment Patricia Baquedano-López, Graduate School of Education, University of California, Berkeley Pedro Jose Garcia-Sanchez, Département de Sociologie, Université Paris Ouest Social and political tools of urban cosmopolitanism: The challenge of otherness in distributed cognition and interactivity 156 France-Berkeley Fund Funded Pro�ects BY Field Annual Report 2013-2014 157 Applied Sciences Pablo Ross, Department of Animal Science, University of California, Davis Hélène Jammes, Unité Biologie du Développement et Reproduction, INRA A systems biology approach to understand parental specific contributions to embryo and placenta development 2013 Jack L. Gallant, Department of Psychology, University of California, Berkeley Bertrand Thirion, Neurospin, INRIA France Improving fMRI by using anatomical data to constrain functional models. 2012 Michael A. Rogawski, Department of Neurology, School of Medicine, University of California, Davis Jean-Pierre Mothet, Centre de Recherche en Neurobiologie et Neurophysiologie, Faculté de Médecine, Université Aix-Marseille Role of D-serine in migraine 2012 Jeffrey Ross-ibarra, Department of Plant Sciences, University of California, Davis Maud Tenaillon, UMR 8120 de Génétique Végétale, INRA / Université Paris XI / CNRS / INA PG Does domestication affect recombination: a pilot study in maize 2012 Igor V. Grigoriev, Doe Joint Genome Institute, Lawrence Berkeley National Laboratory Francis M. Martin, Institut National de la Recherche Agronomique, Université de Lorraine, Nancy Uncovering evolutionary origins and mechanisms of mycorrhizal symbiosis and wood decay machinery in forest ecosystems by comparative genomics 2012 Dmitry Budker, Department of Physics, University of California, Berkeley Jean-François Roch, Ecole Normale Supérieure de Cachan Magnetometry with color centers in diamond 2011 Wim Leemans, Lawrence Berkeley National Laboratory Philippe Martin, CEA Saclay Electron acceleration and relativistic optics in the ultra-high-intensity regime 2011 Michael A. Lieberman, Electrical Engineering and Computer Sciences, University of California, Berkeley Pascal Chabert, Ecole Polytechnique, Palaiseau Global model of radiofrequency atmospheric pressure plasmas used for biomedical applications 2011 Diane M Beckles, Plant Sciences, University of California, Davis Maria Cecilia Arias, Université des Sciences et Technologies de Lille Molecular evolution of starch transcriptional networks in plants 2011 Sandrine Dudoit, Division of Biostatistics, University of California, Berkeley Jean-Philippe Vert, Centre for Computational Biology, Mines Paris Tech Statistical methods for the joint analysis of high-throughput transcription and genotype data 2011 Ian Faloona, Department of Land, Air, and Water Resources, University of California, Davis Marie Lothon, Université de Toulouse A study of the late afternoon transition in the atmospheric boundary layer 2011 158 France-Berkeley Fund Alexandre J. Chorin, Department of Mathematics, University of California, Berkeley Yvon Maday, Université Pierre et Marie Curie, Paris Reduced basis method for the simulation of coupled QM/continuum solvation models 2011 Mark van der Laan, Group in Biostatistics, University of California, Berkeley Antoine Chambaz, Laboratoire MAP5,Université Paris Descartes Development of causal inference methodology and its application to medical and epidemiological research in France? 2010 Applied Sciences Kevin Wilson, Chemical Sciences Division, Lawrence Berkeley National Laboratory Christa Fittschen,UFR Chimie, Université de Lille, Villeneuve d’Ascq Experimental Investigations of complex kinetic mechanism by combining state-of-the-art experimental techniques 2010 Angelique Louie, Biomedical Engineering, University of California, Davis Marc Dhenain,URA CEA CNRS 2210-CEA – MIRCen Center, Fontenay aux Roses New method to detect amyloid plaques in Alzheimer’s disease 2010 John Verboncoeur, Department of Nuclear Engineering, University of California, Berkeley Eric Sonnendrücker, Institut de Recherche Mathématique Avancée, Université de Strasbourg Adaptive multilevel particle schemes for plasma simulation 2010 John Radke, Landscape Architecture and Environmental Planning, University of California, Berkeley Frédéric Liébault, Cemagref Groupement de Grenoble, Saint-Martin-d’Hères Analysis of historic river corridor response to landscape change and application to river management principles in California and France 2010 David Wessel, CNMAT, University of California, Berkeley Yann Orlarey, GRAME - Centre National de Création Musicale, Lyon Parallelism in interactive real-time signal processing with FAUST and OSC 2010 Pascale Garaud, Baskin School of Engineering, University of California, Santa Cruz Michel Rieutord, Laboratoire d’Astrophysique, Observatoire Midi Pyrenées, Toulouse Proposal to support an international summer program in astrophysical modeling 2009 Nobuhiko P. Kobayashi, Electrical Engineering, Jack Baskin School of Engineering, University of California, Santa Cruz Natalio Mingo, LITEN, CEA-Grenoble Collaborative research on “nanoparticle embedded in alloy” thermoelectric materials and devices grown by MOCVD 2009 Richard H. Kramer, Department of Molecular and Cell Biology, University of California, Berkeley Alexandre Specht, Départementde Chimie Bioorganique Université Louis Pasteur, Strasbourg New two-photon caged neurotransmitters for the photocontrol of neuronal activity and physiology 2009 Richard grotjahn and susan Ustin, Department of L.A.W.R, University of California, Davis Fabio D’Andrea, Laboratoire de Météorologie Dynamique, Ecole Normale Supérieure, Paris Calibration and mapping of satellite skin temperatures by surface station data with evaluation of WRF guidance for extreme heat waves 2009 Peter S. Nico, Earth Sciences Division, Lawrence Berkeley National Laboratory Delphine Derrien, Laboratoire Biogéochimie des Ecosystèmes Forestiers, INRA Nancy Do mineral surfaces stabilize organic matter in soil? 2009 Annual Report 2013-2014 159 Applied Sciences André Anders, Plasma Applications Group, Lawrence Berkeley National Laboratory Jean-Philippe Bauer, Department CP2S, Institut Jean Lamour, Nancy Université Spatial and temporal development of high power impulse magnetron sputtering discharges 2009 Alexandra Navrotsky, NEAT-ORU and Thermochemistry Facility, University of California, Davis. Christophe Drouet and Sophie Guillemet, CIRIMAT, UMR CNRS 5085, INSIACET, Toulouse A thermodynamic approach for the understanding of nanomaterials properties 2008 George Brooks, Department of Integrative Biology, University of California, Berkeley Laurent Messonnier, Laboratory of Exercise Physiology and Physiopathology, Université de Savoie, Le Bourget du Lac, Effects of endurance training on glucose and lactate metabolism during exercise and recovery in men and women—advancing our knowledge and methods of investigation 2008 Juan F. Medrano, Department of Animal Science, University of California, Davis Patrice Martin, Institut National de la Recherche Agronomique, Jouy-en-Josas Contribution of genomics to the understanding of milk fat composition using gene expression profiling of mammary epithelial cells islated from milk and microdissected biopsies 2008 Steven R. Beissinger, Department of Environmental Science, Policy and Management, University of California, Berkeley Jean-Dominique Lebreton, Centre d’Ecologie Fonctionnelle et Evolutive, CNRS UMR 5175, Montpellier Integrated approach for population viability analyses with limited data 2008 George Roderick, Environmental Science, Policy and Management, University of California, Berkeley Maria Navajas, INRA, Centre de Biologie et Gestion des Populations, Montferrier-sur-Lez Invasive insects and mites of Mediterranean climates 2007 Alessandra Lanzara, Materials Sciences Division, Lawrence Berkeley National Laboratory Matteo D’Astuto, Institut de Minéralogie & Physique des Milieux Condenses, Université Pierre et Marie Curie, Paris 6 Electron phonon interaction in new intercalated layered systems 2006 Gary Karpen, Department of Genome Biology, Lawrence Berkeley National Laboratory G. Almouzni, Institut Curie, Paris High-resolution analysis of mouse centromeric heterochromatin organization 2006 Diane M. Beckles, Department of Plant Sciences, University of California, Davis Nadia Bertin, Institut National de la Recherche Agronomique, Avignon Analysis of carbon allocation in transgenic tomatoes via molecular and ecophysiological approaches 2006 Roberto Horowitz, Department of Mechanical Engineering, University of California, Berkeley Carlos Canudas-de-Wit, Laboratoire d’Automatique Grenoble, Saint-Martin-d’Hères Toward coordinated and traffic responsive ramp metering strategies 2005 Peter J. Bickel, Department of Statistics, University of California, Berkeley Alexandre Tsybakov, Laboratoire de Probabilités et Modèles Aléatoires, Université Paris 6, CNRS UMR 7599, Paris How can prediction be possible when data are high dimensional? 2005 160 France-Berkeley Fund Costas Grigoropoulos, Department Mechanical Engineering, University of California, Berkeley Jean-Jacques greffet, Laboratoire EM2C, Ecole Centrale, Chatenay-Malabry Nanoscale heat transfer 2005 Rachel A Segalman, Department of Chemical Engineering, University of California, Berkeley Cyril Brochon, Département de Polymères, Ecole Européenne de Chimie, Strasbourg Nanopatterning and electrical properties of insulated molecular wires 2005 Applied Sciences Piedong Yang, Department of Chemistry, University of California, Berkeley François Lagugne-Labarthet, LPCM, UMR5803 CNRS Bordeaux Spectroscopy of one-dimensional semiconductor nanostructures 2004 Joseph Campos, Institute of Human Development, University of California, Berkeley Marianne Barbu-Roth, LPBD, Ecole pratique des Hautes Etudes, Paris Are newborns programmed to walk on the Earth? 2004 Dean Toste, Department of Chemistry, University of California, Berkeley Jean-Marc Campagne, ICSN, CNRS Gif-sur-Yvette Synthesis of bioactive polyol natural product by catalytic asymmetric mukaiyama adool and olefin hydration 2004 Sandrine Dutoit, School of Public Health, University of California, Berkeley Jean-Daniel Zucker, CNRS- STIC team, Université Paris XIII OBELINK: Combining machine learning and biostatics to discover significant obesity related genetics polymorphisms 2003 Donald C. Rio, Department of Molecular and Cell Biology, University of California, Berkeley Bertrand Séraphin, CNRS-Centre de Génétique Moléculaire In vitro study of the exon-junction complex assembly in Drosophila 2003 Ronald Amundson, Division of Ecosystem Sciences, University of California, Berkeley Isabelle Basille, CEREGE-Université Aix-Marseille III Carbon cycle in soils: role of organic matter 2002 Slawek Tulaczyk, Department of Earth Sciences, University of California, Santa Cruz Catherine Ritz, Laboratoire de Glaciologie et Géophysique de l’Environnement Possible near-future break-up of the Ross Ice Shelf and other forms of unstable behavior of the Antarctic Ice Sheet: Evaluating the impact of decreasing ice discharge from the Ice Streams 2002 Christos Papadimitriou, Computer Science Division, University of California, Berkeley Evripidis Bampis, Laboratoire de Méthodes Informatiques, Université d’Evry Val d’Essonne MULT-APPROX: Multiobjective optimization and approximation 2001 saul Perlmutter, Physics Division, Lawrence Berkeley National Laboratory Pierre Antilogus, Institut de Physique Nucléaire de Lyon Nearby supernova factory project (software) 2001 Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Joseph Remillieux, Institut de Physique Nucléaire de Lyon Experimental studies of vacuum-assisted photoionization 2000 Annual Report 2013-2014 161 Applied Sciences Carole Meredith, Department of Viticulture and Enology, University of California, Davis Jean-Michel Boursiquot, ENSA, Montpellier DNA Profiling and parentage analysis of grape varieties held in the INRA collection at domaine de vassal 2000 Norman Terry, Department of Plant and Microbial Biology, University of California, Berkeley Jean-Claude Davidian, ENSA-INRA, Montpellier Mechanisms of selenium uptake, sequestration and resistance in arabidopsis and yeast mutants 2000 Richard scheffler, School of Public Health, University of California, Berkeley Christine Huttin, Université de Paris X-Nanterre The growth of private insurance and managed care in France: Insights from the American experience 2000 Robert BonDurant, School of Veterinary Medicine, University of California, Davis Francis Fieni, Ecole Nationale Vétérinaire de Nantes Transmission of CAE retrovirus via breeding technologies in dairy goats 1999 Daniel S. Chemla, Materials Sciences Division and Advanced Light Source, Lawrence Berkeley National Laboratory Jérôme Tignon, Laboratoire de Physique de la Matière Condensée, Ecole Normale Supérieure, Paris Spectroscopie optique non linéaire de nanostructures de semiconducteurs 1999 James H. Underwood, Center for X-Ray Optics, Lawrence Berkeley National Laboratory Coryn Frank Hague, Laboratoire de Chimie Physique, Université de Paris VI Magneto-optics of polarized soft X-rays 1999 Hiroshi Nikaido, Department of Molecular and Cell Biology, University of California, Berkeley Patrick Plésiat, Laboratoire Bactériologie, Faculté Médecine, Université Franche-Comté, Besançon Characterization of a New Multidrug Efflux Pump in Pseudomonas aeruginosa 1998 Jeffrey granett, Department of Entomology, University of California, Davis François Leclant, UFR d’Ecologie animale et de Zoologie agricole, ENSA-INRA, Montpellier Understanding Genetic Variability of Grape Phylloxera 1998 Mack Kennedy, Center for Isotope Geochemistry, Earth Science Division, Lawrence Berkeley National Laboratory Simon Sheppard, Laboratoire des Sciences de la Terre, Ecole Normale Supérieure de Lyon Origin and role of fluids involved in active faulting 1998 Frank McLarnon, Department of Chemical Engineering, University of California, Berkeley Françoise Argou, Centre de Recherche Paul Pascal, Pessac Application of advanced optical techniques for probing interfacial electrochemical processes 1997 Brian Staskawicz, Department of Plant Biology, University of California, Berkeley Ulla Bonas, Institut des Sciences Végétales, Gif-sur-Yvette Identification and characterization of novel genes for disease resistance in capsicum annum 1997 Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Joseph Remillieux, Institut de Physique Nucléaire et Université Lyon I Production and study of exotic atoms 1996 162 France-Berkeley Fund Alexandre J. Chorin, Department of Mathematics, University of California, Berkeley Denis Talay, Institut National de Recherche en Informatique et en Automatique, Sophia Antipolis Les systèmes de particules aléatoires et les applications numériques en mécanique des fluides 1996 Russell Jones, Department of Plant Biology, University of California, Berkeley Raoul Ranjeva, Centre de Physiologie Végétale, Université P. Sabatier, Toulouse Isolation and characterization of calcium channels in plants 1996 Applied Sciences C. Bradley Moore, Department of Chemistry, University of California, Berkeley Pascal Devolder, Université des Sciences et Technologies de Lille, Villeneuve d’Ascq Kinetic investigations of reactive systems by combined laser photolysis/tunable diode absorption spectroscopy and LIF 1996 Hans Rudolf Wenk, Department of Geology and Geophysics, University of California, Berkeley. Michel Pernet, Laboratoire de Cristallographie–CNRS, Grenoble Texture and anisotropy 1996 Catherine P. Koshland, School of Public Health, University of California, Berkeley sebastien Candel, Laboratoire EM2C de L’ECP et du CNRS, Châtenay-Malabry A strategy to reduce emissions during thermal oxidation of hazardous wastes 1995 Pravin Varaiya, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Joseph Sifakis, VERIMAG, Montbonnot Saint-Martin Analysis of hybrid systems: application to the PATH project 1995 Y. R. Shen, Department of Physics, University of California, Berkeley E. Courtens, LSMV CC069, Université Montpellier II Non-linear optics in porous materials 1995 Daniel S. Chemla, Materials Sciences Division, Lawrence Berkeley National Laboratory Pierre Lefebvre, Groupe d’Etude des Semiconducteurs, Université Montpellier II Optical properties of nanostructures. Low-dimensional excitonic effects 1995 Brian A. Barsky, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Jean Sequeira, Informatique, Faculté des Sciences de Luminy, Université Aix-Marseille II Geometric modeling of the cornea using videokeratography 1994 David Dornfeld, Engineering Systems Research Center, University of California, Berkeley Serge Tichkiewitch, Centre de Recherche en Automatique de Nancy, Nancy Intégration des procédés de fabrication en conception de produits 1994 Steven G. Louie, Department of Physics, University of California, Berkeley gerard Martinez, Physics, Université Joseph Fourier, Grenoble Electron correlation effects in condensed matter system as the newly discovered fullerene-based materials 1994 Barbara Romanowicz, Department of Geology and Geophysics, University of California, Berkeley Claude Froidvaux, Ecole Normale Supérieure, Paris Global geophysics 1994 Annual Report 2013-2014 163 Exact Sciences Barbara Romanowicz, Department of Earth and Planetary Science, University of California, Berkeley Yann Capdeville, Laboratoire de Planétologie et Géodynamique de Nantes Probabilistic interpretation of seismic tomographic models 2013 Wayne Marcus Getz, Department of Environmental Sciences, Policy and Management, University of California, Berkeley Pierre Magal, Institut de Mathématiques de Bordeaux, Université Bordeaux Segalen Individual-based, structurally and demographically-detailed epidemic models 2013 Lauren Williams, Department of Mathematics, University of California, Berkeley Sylvie Corteel, CNRS et Universite Paris Diderot Tableaux combinatorics 2013 John P. Huelsenbeck, Department of Integrative Biology, University of California, Berkeley Vincent Daubin, Laboratoire de Biométrie et Biologie Evolutive, Université Lyon 1 Claude Bernard User-friendly phylogenomics: Bayesian simultaneous reconstruction of gene trees and species trees 2013 Daniela Kaufer, Department of Integrative Biology and Helen Wills Neuroscience Institute, University of California, Berkeley Francois Tronche, Gene Regulation and Adaptive Behaviors team, CNRS Dissecting GR gene function in adult brain stem cells 2013 Robert T. Knight, Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley Fanny Meunier, Centre de Recherche en Neurosciences de Lyon Brain dynamics of compensatory mechanisms for lexical selection in overt speech production after left prefrontal damage 2013 Nicolai Reshetikhin, Department of Mathematics, University of California, Berkeley Christian Blanchet, Institut de Mathématiques de Jussieu, Université Paris Diderot Categorification of quantum invariants of 3-dimensional manifolds 2013 geoff Bower, Department of Astronomy, University of California, Berkeley Gilles Thereau, Station de Radioastronomie de Nançay Observatoire de Paris French / American collaboration for radio investigations of time-variable astrophysical phenomena 2013 Lance J. Kriegsfeld, Department of Psychology, University of California, Berkeley Matthieu Keller, CNRS, Équipe Neuroendocrinology des Interactions et Comportements Sexuels Neuroendocrine gating of olfactory perceptual processing 2013 David Chandler, Department of Chemistry, University of California, Berkeley Benjamin Rotenberg, Chimie, Université Pierre et Marie Curie, Paris Optimizing self-assembly of complex colloidal systems using Transition Path Sampling 2012 Ehud isacoff, Department of Molecular and Cell Biology, University of California, Berkeley Nicole Ropert, Laboratoire de Neurophysiologie et Nouvelles Microscopies, Université Paris Descartes, Paris Optogenetic probing of the mechanisms and functions of gliotransmission 2012 Steven G. Louie, Department of Physics, University of California, Berkeley gérard Martinez, Laboratoire National des Champs Magnétiques, Centre National de la Recherche Scientifique, Grenoble Joint experimental and theoretical study of electron-electron and electron-phonon interactions in graphene-based compounds and topological insulators with magneto-optical spectroscopy 2012 164 France-Berkeley Fund Marla Feller, Department of Molecular and Cell Biology, University of California, Berkeley David DiGregorio, Institut Pasteur, Centre National de la Recherche Scientifique, Paris Dendritic processing of synaptic input in retinal interneurons 2012 geoffrey W. Marcy, Department of Astronomy, University of California, Berkeley Guillaume Hébrard, Institut d’Astrophysique de Paris / Observatoire de Haute-Provence Combining French and American telescopes to characterize exoplanets 2012 Exact Sciences Alejandro Aguilar, Advanced Light Source, Lawrence Berkeley National Laboratory Jean-Marc Bizau, Institut des Sciences Moléculaires d’Orsay, Université Paris-Sud First absolute single-photon double photoionization cross section measurements of fundamental 2-electron negative ion: H2012 John Taylor, Department of Plant and Microbial Biology, University of California, Berkeley tatiana giraud, Département Génétique et Ecologie Evolutives, Université de Paris-Sud Genomics of ecological divergence in the fungal species Neurospora discreta 2012 Kunxin Luo, Department of Molecular and Cell Biology, University of California, Berkeley Delphine Javelaud, INSERM U1021, Institut Curie, Paris Hippo signaling and Ski in human melanoma development 2012 Daniel Fletcher, Department of Bioengineering and Biophysics, University of California, Berkeley Patricia Bassereau, Laboratoire PhysicoChimie Curie, Institut Curie, Paris Mechanical induction of transcellular tunnels 2012 Jeremy W. Thorner, Department of Molecular and Cell Biology, University of California, Berkeley Robert A. Arkowitz, CNRS UMR7277 /INSERM UMR1091, Université de Nice—Sophia Antipolis Requirements, molecular roles and distribution of membrane phosphoinositides in yeast external signal-dependent polarized growth 2012 Bo Liu, Department of Plant Biology, University of California, Davis David Bouchez, Institut Jean-Pierre Bourgin Uncovering an interactive protein network that regulates microtubule nucleation and organization for plant cell growth 2012 Stephen R. Leone, Departments of Chemistry and Physics, University of California, Berkeley Ian R. Sims, Institut de Physique de Rennes, Université de Rennes 1 Direct measurements of reaction pathways for interstellar and planetary low temperature chemistry 2012 Charles Marshall, Department of Integrative Biology, UCB / University of California Museum of Paleontology Hélène Morlon, Centre de Mathématiques Appliquées de l’Ecole Polytechnique, Palaiseau Integrating molecular phylogenies and the fossil record. 2012 Kenneth Ribet, Department of Mathematics, University of California, Berkeley Ariane Mézard, Laboratoire de Mathématiques de Versailles, Université de Versailles Saint-Quentin Summer 2013 workshop on new geometric techniques in number theory 2012 Kenneth Downing, Life Sciences Division, Lawrence Berkeley National Laboratory Manfred Heinlein, Institut de Biologie Moléculaire des Plantes, Strasbourg Structural and functional analysis of the Tobacco mosaic virus movement protein:tubulin complex 2011 Annual Report 2013-2014 165 Exact Sciences Dietmar Kueltz, Department of Animal Science, University of California, Davis Jean-Herve Lignot, Université Montpellier 2 Parallel evolution of osmoregulatory mechanisms in fish 2011 Trent Northen, Life Sciences Division, Lawrence Berkeley National Laboratory Marion Leclerc, Microbiologie-Institut National de la Recherche Agronomique In vitro and in vivo metabolic interaction in a simplified human gut microbiome 2011 Michael Levine, Department of Molecular and Cellular Biology, University of California, Berkeley Krzysztof Jagla, Université de Clermont Transcriptional regulation of cell fate decisions during Drosophila cardiovascular development 2011 Eva Harris, School of Public Health, University of California, Berkeley Bruno Canard, Université de la Méditerranée Aix-Marseille The role of NS3 and NS5 in dengue viral fitness 2011 Theodore A. Slaman, Department of Mathematics, University of California, Berkeley Laurent Bienvenu, Université Paris Diderot Effective randomness for non-uniform measures 2011 Robert Tjian, Department of Molecular and Cellular Biology, University of California, Berkeley Xavier Darzacq, Institut de Biologie de l’Ecole Normale Supérieure, Paris Spatiotemporal dynamics of single transcription factors in eukaryotic cells 2011 David L. Shuster, Department of Earth and Planetary Science, University of California, Berkeley Jean Braun, Institut des Sciences de la Terre (ISTerre), Université de Grenoble Catastrophic gorge incision (Skagit River Gorge) induced by glacial lake overspill assessed through high-resolution 4He/3He thermochronology 2011 Wolf-Dietrich Heyer, Department of Microbiology, University of California, Davis Xavier Veaute, CEA, Fontenay aux Roses Fonctions des paralogues de Rad51 dans la recombinaison homologue. 2010 Bruno Nachtergaele, Department of Mathematics, University of California, Davis Valentin Zagrebnov, Département de Physique, Université de la Méditerranée, Marseille Application of the Lieb-Robinson bound method to study dynamics of infinite systems 2010 Patrick V. Kirch, Departments of Anthropology and Integrative Biology, University of California, Berkeley Eric Conte, Archéologie, Université Paris1, Université de la Polynésie Française, Tahiti Paleo- and neo-ecology of French Polynesia 2010 Junko Yano, Physical Biosciences, Lawrence Berkeley National Laboratory and University of California, Berkeley Cyrille Costentin, Laboratoire d’Electrochimie Moléculaire, Université Paris Diderot, Paris 7 Mechanism of water oxidation catalysis using electrochemistry and in situ X-ray spectroscopy 2010 Frederic Theunissen, Department of Psychology and Helen Wills Neurosciences Institute, University of California, Berkeley Nicolas Mathevon, Université Jean Monnet, Saint-Etienne Auditory scene analysis in the songbird 2010 166 France-Berkeley Fund Kristofer S. J. Pister, College of Engineering, University of California, Berkeley David Simplot-Ryl, INRIA POPS, Université de Lille Implementation and extensive performance evaluation of future standards for wireless sensor networks 2010 Thomas Jue, Department of Biochemistry and Molecular Medicine, University of California, Davis David Bendahan, Centre de Résonance Magnétique Biologique Médicale, Faculté Médecine Timone, Marseille Determination of metabolic transients during a muscle contraction using hyperpolarized 13C, 31P and 1H magnetic resonance spectroscopy 2010 Exact Sciences Sharman D. O’Neill, Department of Plant Biology, College of Biological Sciences, University of California, Davis Pascale Besse, Université de la Réunion, Peuplements Végétaux et Bioagresseurs en Milieu Tropical, La Réunion The France-UC Vanilla Consortium: an international collaboration for genomic research and germplasm conservation for crop improvement of vanilla planifolia 2010 Barbara Romanowicz, Earth and Planetary Science, University of California, Berkeley Jan Matas, Ecole Normale Supérieure, Lyon Seismic attenuation in the Earth’s mantle: implications for velocity-to-density conversion factors 2009 Siobhan Brady, Section of Plant Biology and Genome Center, University of California, Davis François Roudier, Biology Department, Ecole Normale Supérieure, Paris Integrating transcriptional networks and chromatin-based mechanisms involved in the control of cell differentiation in the model plant Arabidopsis thaliana 2009 Zahid Hussain, Advanced Light Source, Lawrence Berkeley National Laboratory Marino Marsi, Laboratoire de Physique des Solides – Université Paris-Sud, Paris New spectroscopic approaches for the study of strongly correlated materials 2009 Johan Leveau, Department of Plant Pathology, University of California, Davis Pascale Frey-Klett, Institut National de la Recherche Agronomique, Champenoux Impact of bacterial-fungal interactions on soil evolution, fertility, and vegetation 2009 Vittal Yachandra, Physical Biosciences Division, Lawrence Berkeley National Laboratory Pieter Glatzel, Installation Européenne de Rayonnement Synchrotron, Grenoble Ligands of manganese complexes relevant to photosynthetic water oxidation: direct detection using X-ray emission spectroscopy 2009 Artyom Kopp, Department Of Ecology and Evolution, University of California, Davis Nicolas Gompel, Institut de Biologie du Développement de Marseille-Luminy, Marseille Developing genetic tools for new model species of Drosophila 2009 Robert littlejohn, Department of Physics, University of California, Berkeley Carlo Rovelli, Centre de Physique Théorique, Luminy, Marseille Semiclassical studies of spin networks, Wigner $3nj$- symbols, and quantum gravity 2009 Rosemary Gillespie, Department of Environmental Science, Policy, and Management, University of California, Berkeley Christophe Thébaud, Sciences de la Vie et de la Terre, Université Paul Sabatier, Toulouse Community assembly on islands: role of random versus deterministic effects 2009 Annual Report 2013-2014 167 Exact Sciences Adrian T. Lee, Department of Physics, University of California, Berkeley Radoslaw Stompor, Laboratoire Astroparticule et Cosmologie, Université Paris 7 Simulations and data analysis of the initial data set of a next generation CMB B-mode polarization experiment: PolarBeaR 2009 Alan Weinstein, Department of Mathematics, University of California, Berkeley Pierre Schapira, Institut de Mathématiques de Jussieu, Université Paris VI Categorical tools in geometry and in mathematical physics 2009 Robert Kostecki, Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory Christian Julien, Institut des Nanosciences, Université Pierre et Marie Curie – Paris 6 Electrochemical energy storage research advanced cathode materials for Li-ion battery systems 2009 Louise Glass, Plant and Microbial Biology, University of California, Berkeley Mathieu Paoletti, Laboratoire de Génétique Moléculaire des Champignons, Université Victor Segalen Bordeaux 2 Role of the HET domain in fungal nonself recognition 2008 George Smoot, Department of Physics, University of California, Berkeley James g. Bartlett, Département de Physique, Université Paris 7 Denis-Diderot, Paris Empowering the CMB: measuring power spectra from the Planck mission 2008 Judith P. Klinman, Departments of Chemistry & Molecular and Cell Biology, University of California, Berkeley Nicolas Mano, CRPP-UPR 8641, Pessac A miniature membraneless biofuel cell 2008 Jere H. Lipps, Museum of Paleontology, University of California, Berkeley Marie-Thérèse Vénec-Peyré, Département Histoire de la Terre, Université de Paris 6, Paris Effect of pollution on foraminifera 2008 William A. Lester, Department of Chemistry, University of California, Berkeley Roland Assaf, Laboratoire de Chimie Théorique, Université Pierre et Marie Curie, Ivry sur Seine Development of size-independent estimators for quantum Monte Carlo forces 2008 Kurt Cuffey, Department of Geography, University of California, Berkeley Peter Van Der Beek, Observatoire des Sciences de l’Univers de Grenoble, Grenoble Relief development in the Western Alps (France, Switzerland) in response to Quaternary glaciations assessed through High-resolution 4He/3He/He thermochronology 2008 saul Perlmutter, Lawrence Berkeley National Laboratory, Berkeley Gérard Smadja, Institut de Physique Nucléaire de Lyon, Villerbanne The nearby supernova factory 2008 Robert Knight, Helen Wills Neuroscience Institute, University of California, Berkeley Olivier Bertrand, INSERM U821, Centre Hospitalier Le Vinatier, Bron Spatio-temporal organization of cortical oscillatory activities in human audition 2008 168 France-Berkeley Fund Bob B. Buchanan, Department of Plant and Microbial Biology, University of California, Berkeley J.-Ph. Reichheld, LGDP UMR CNRS-IRD-UPVD 5096, Université de Perpignan, Perpignan The next step in the identification of thioredoxin target proteins: in vivo characterization with mutants 2008 Irfan Siddiqi, Quantum Nanoelectronics, Department of Physics, University of California, Berkeley Wolfgang Wernsdorfer, Institut Néel, Nanosciences Department, CNRS, Grenoble Microwave nanomagnetometry of single molecules, towards single spin measurement and control 2008 Exact Sciences David Feldheim, Department of Molecular and Developmental Biology, University of California, Santa Cruz Fanny Mann, IBDML, CNRS UMR 6216 Marseille Monitoring the assembly and function of retinal circuits. 2007 Jeffrey R. long, Department of Chemistry, University of California, Berkeley Rodolphe Clérac, Centre de Recherche Paul Pascal, UPR CNRS 8641, Pessac Photomagnetic metal-cyanide clusters 2007 Maria Schonbek, Department of Mathematics, University of California, Santa Cruz Dragos iftimie, Institut Camille Jordan, Université Lyon 1, Villeurbanne Asymptotic behavior for the quasi-geostrophic system and the Euler equations. 2007 Maciej Zworski, Department of Mathematics, University of California, Berkeley Nicolas Burq, Département de Mathématiques, Université Paris Sud, Orsay Mathematical aspects of semiclassical approximation. 2007 Richard M. Allen, Department of Earth and Planetary Science, University of California, Berkeley Nikolai Shapiro, Département de Sismologie, Institut de Physique du Globe de Paris, Paris Seismic tremor: a new window to monitor seismic/aseismic coupling at depth and improve earthquake forecasting. 2007 Hitoshi Murayama, Department of Physics, University of California, Berkeley Emilian Dudas, Ecole Polytechnique, Palaiseau Electroweak symmetry breaking in the LHC era 2007 El Karoui Nouredine, Department of Statistics, University of California, Berkeley Touzi Nizar & El Karoui Nicole, Centre de Mathématiques Appliquées, Ecole Polytechnique, Palaiseau Random matrix theory and mathematical finance 2007 Kristin scott, Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley Frederic Marion-Poll, INRA, Physiologie de l’Insecte: Signalisation et Communication, Versailles Diversity of bitter tastes in Drosophila. 2007 Xiaoye Sherry Li, Lawrence Berkeley National Laboratory iain s. Duff, CERFACS, Parallel Algorithms Project, Toulouse scalable sparse linear equation solvers on emerging petascale computers. 2007 Warren Pickett, Department of Physics, University of California, Davis Mébarek Alouani, Institut de Physique et Chimie des Matériaux, Université Louis Pasteur, Strasbourg charge mismatch and magnetism at interfaces. 2007 Annual Report 2013-2014 169 Exact Sciences Ali Belkacem, Chemical Sciences Division, Lawrence Berkeley National Laboratory Hamed Merdji, Commissariat à l’Energie Atomique, Centre d’Etude de Saclay, Gif-sur-Yvette Development of high intensity high harmonic system for studies of non-linear X-Ray optics 2007 Qing-Zhu Yin, Department of Geology, University of California, Davis Philippe Gillet, Laboratoire des Sciences de la Terre, Ecole Normale Supérieure, Lyon Davis-Lyon joint investigation of non-traditional stable isotope systematics in the early solar system materials 2007 Alison M. Berry, Department of Plant Sciences, University of California, Davis Philippe Normand, CNRS-UMR 5557 Ecologie Microbienne, Villeurbanne Global computational approaches to discovery of microbial gene function and evolution: phylogenomic comparison of two plantassociated Actinobacteria, the thermotolerant biomass-degrader Acidothermus, and the symbiotic nitrogen-fixer Frankia 2007 Rebecca Heald, Molecular and Cell Biology, University of California, Berkeley Andreas Merdes, CNRS Toulouse In vitro approaches to study muscle morphogenesis 2006 James R. Graham, Department of Astronomy, University of California, Berkeley Garpard Duchêne, Laboratoire d’Astrophysique, Observatoire de Grenoble, Grenoble Studying the properties of protoplanetary disks across wide ranges of stellar ages and masses 2006 Andrew Chisholm, Department of Molecular and Cell Biology, University of California, Santa Cruz Jonathan Ewbank, Centre d’Immunologie de Marseille-Luminy, Marseille A kinase linking autophagy and innate immunity in C. elegans 2006 Neil Hunter, Center for Genetics and Development, Section of Microbiology, University of California, Davis Bernard De Massy, Institut de Génétique Humaine, UPR1142/CNRS, Montpellier The crossing-over pathway during meiosis in mouse 2005 John Bowek, Lawrence Berkeley National Laboratory Michael Meyer, Laboratoire d’Interaction du Rayonnement X avec la Matière; Centre Universitaire Paris-Sud, Orsay Fundamental photoionization processes in excited isolated species 2005 Barbara A. Romanowicz, Berkeley Seismological Laboratory, University of California, Berkeley Jean-Pierre Vilotte, Département de Sismologie, Institut de Physique du Globe de Paris Spectral element method implementation for regional tomography of the Earth’s upper mantle 2005 Sergey Nuzhdin, Section of Evolution and Ecology, University of California, Davis Pierre Capy, Laboratoire Populations, Génétique et Evolution, Gif-sur-Yvette, Genomics of incipient speciation in Drosophila melanogaster 2005 Randy Schekman, Department of Mol. and Cell Biology, University of California, Berkeley Bruno Antonny, CNRS Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne Architecture of the COPII coat and mechanisms of vesicle formation 2005 170 France-Berkeley Fund Nilabh Shastri, Department of Molecular and Cell Biology University of California, Berkeley Philippe Pierre, Centre d’Immunologie de Marseille-Luminy UMR 6102 INSERM CNRS Marseille Cryptic antegenic peptide processing in dendritic cells 2005 Ehud isacoff, Department Of Molecular and Cell Biology, University of California, Berkeley Serge Charpak, Laboratoire de Neurophysiologie, ESPCI/INSERM Paris Manipulation and detection of olfactory functions 2005 Exact Sciences Robert Tjian, Molecular and Cell Biology Department, University of California, Berkeley Olivier Bensaude, CNRS UMR 8541-Ecole Normale Supérieure – Régulation de L’Expression Génétique, Paris Imaging of the eukaryotic transcription machinery in living cells 2005 Gerson Goldhaber, Department of Physics, University of California, Berkeley Reynald Pain, LPNHE, Université Paris VI & VII Measuring the cosmic vacuum energy 2004 A. R. Flegal, Environmental Toxicology, University of California, Santa Cruz A. Veron, CEREGE, UMR6635, CNRS Université Aix-Marseille III Coral reconstruction of rapid changes in air mass & ocean circulation in the North Atlantic within the past 200 years 2004 Bob B. Buchanan, Department of Plant and Microbial Biology, University of California, Berkeley Françoise Montrichard, UMR 1191 INH INRA Université d’Angers Exploring the mechanism of germination in leguminous seeds 2004 Judith Klinman, Department of Chemistry, University of California, Berkeley Marius Réglier, CNRS 7517, Université d’Aix-Marseille 02 Activation in metallobiochemistry: probes for the functional copper-oxygen species in the neuroactive enzymes, DbM and PHM 2004 Vittal Yachandra, Physical Biosciences Division, Lawrence Berkeley National Laboratory Sun Un, CNRS URA 2096, CEA Saclay Single crystal multifrequency EPR and EXAFS studies of multinuclear Mn complexes relevant to the oxygen-evolving complex in Photosystem II 2004 Brigitta Whaley, Department of Chemistry, University of California, Berkeley Alexandra Viel, UMR 56+26 IRSAMC, Université Toulouse Atomic and molecular probes of superfluids 2004 Richard Harland, Molecular and Cellular Biology, University of California, Berkeley Anne-Hélène Monsoro-Burq, UMR146, CNRS Institut Curie, Orsay Gene profiling in early neural crest development 2004 Anne Britt, Department of Plant Biology, University of California, Davis Marie-Edith Chaboute, IBMP/CNRS Université Louis Pasteur Strasbourg Plant response to replication stress 2004 David H. Raulet, Department of Molecular and Cell Biology, University of California, Berkeley Eric Vivier, Centre d’Immunologie de Marseille-Luminy The role of immune receptors in vivo 2003 Annual Report 2013-2014 171 Exact Sciences Georges F. Smoot, Department of Physics, University of California, Berkeley James g. Barlett, Collège de France, Laboratoire de Physique Corpusculaire et Cosmologie Precision cosmology from CMB analysis 2003 Eva Harris, School of Public Health, University of California, Berkeley Chris Mueller, INSERM-CNRS Infection of dermal dendrocytes with clinical isolates of dengue virus 2003 Daniel S. Chemla, Department of Physics, University of California, Berkeley Jerome Tignon, Ecole Normale Supérieure, LPMC Condensation des polaritons de microcavité de semiconducteurs 2003 William A. Lesler, Department of Chemistry, University of California, Berkeley Michel Caffarel, Laboratoire de Chimie Théorique, CNRS-Université Paris VI Quantum Monte Carlo for molecules 2003 Roland Burgmann, Department of Earth and Planetary Science, University of California, Berkeley Edouart Kaminski, Institut de Physique du Globe, Université Paris VII Seismic anisotropy in the San Andreas Shear Zone 2003 Barry Sinervo, Department of ecology and Evolutionary Biology, University of California, Santa Cruz Michael Hochberg, CNRS-Institut des Sciences et de l’Evolution, Université de Montpellier II Potential role of social interactions in the speciation process 2003 Kunxin Luo, Department of Molecular and Cell Biology, University of California, Berkeley Alain Mauviel, INSERM Blocking of fibrosis by Smad co-repressors 2003 Peter Yu, Department of Physics, University of California, Berkeley Adnen Mlayah, Laboratoire de Physique des Solides, CNRS Université Paul Sabatier, Toulouse Optical scattering from quantum dots nanostructures 2003 A. Chatterjee, Life Sciences Division, Lawrence Berkeley National Laboratory A. Chetioui, Université Pierre et Marie Curie, GPS Biological consequences of inner-shell ionization events on DNA 2002 Eugene Commins, Department of Physics, University of California, Berkeley Francois Combes, LERMA, Observatoire de Paris Supernovae and dust: following the dust from galaxy formation to cosmological parameters 2002 Kurt Cuffey, Department of Geography, University of California, Berkeley Francois Vimeux, CR2 Institut Recherche pour Développement, Laboratoire Sciences du Climat et de l’Environnement Improved precipitation iIotope analyses for climate change studies 2002 John Gunion, Physics Department, University of California, Davis Ulrich Ellwanger, Theoretical Physics Laboratory, Université de Paris-Sud Supersymmetric Higgs Bosons at the Large Hadron Collider 2002 172 France-Berkeley Fund Daniel Tataru, Department of Mathematics, University of California, Berkeley Patrick Gerard, Department of Mathematics, Université de Paris-Sud, Orsay Nonlinear Schrödinger equations and geometry 2002 Kevan Shokat, Department of Chemistry, University of California, Berkeley Michael Sieweke, Centre d’Immunologie de Marseille Luminy Role of subnuclear localization and complex formation of transcription factors in differentiation 2002 Exact Sciences Richard Saykally, Chemistry, University of California, Berkeley and Lawrence Berkeley National Laboratory Claude Roth, Département d›Immunologie, Institut Pasteur, Paris Investigating the physiology of natural killer cells by nonlinear chemical imaging nanomicroscopy 2001 Hei Sook Sul, Department of Nutritional Sciences and Toxicology, University of California, Berkeley Axel Kahn, Institut Cochin de Génétique Moléculaire, INSERM Unité 129, Paris Regulation of fatty acid synthase promoter by AMP-dependent protein kinase 2001 Carl Pennypacker, Space Sciences Laboratory, University of California, Berkeley and LBNL Michel Boër, CNRS FRE 2194 Centre d’Etude Spatiale des Rayonnements, Toulouse Developing an internet-mediated astronomy research/teacher training program for France, U.S. and other nations 2001 Douglas Kellogg, Molecular, Cell and Developmental Biology, University of California, Santa Cruz Robert Arkowitz, CNRS UMR 6543, Centre de Biochimie, Université de Nice G-protein regulation of growth location 2001 Deborah Delmer, Section of Plant Biology, University of California, Davis Herman Höfte, Laboratoire de Biologie, INRA, Versailles The use of Arabidopsis mutants to trace the path of carbon into cellulose in plants 2001 David Deamer, Department of Chemistry and Biochemistry, University of California, Santa Cruz Marie-Christine Maurel, Institut Jacques Monod, Université de Paris VI Oligomerization of thioglumatic acid in membrane defined microenvironments 2001 Imke de Pater, Department of Astronomy, University of California, Berkeley Renée Prangé, Institut d’Astrophysique Spatiale, Université de Paris XI Monitoring and study of Io’s volcanic activity 2001 Jeffrey long, Department of Chemistry, University of California, Berkeley Patrick Batail, Institut des Matériaux Jean Rouxel, Nantes Synthesis and magnetic properties of Re6-nOsnSe8(n=1-3) cluster-organic radical salts 2001 Jesús De Loera, Department of Mathematics, University of California, Davis András Sebö, CNRS Laboratoire Leibniz-IMAG, Grenoble Computer algebra methods in graph theory and optimization 2001 George Smoot, Department of Physics, University of California, Berkeley James Bartlett, Observatoire Midi-Pyrénées, Toulouse Precision Cosmology from CMB data processing and analysis techniques 2000 Annual Report 2013-2014 173 Exact Sciences Qiang Zhou, Department. of Molecular and Cell Biology, University of California, Berkeley Olivier Bensaude, Ecole Normale Supérieure, Paris Functional analysis of RNA-binding activity of the human positive transcription elongation factor, P-TEFb 2000 Edward Berry, Physical Biosciences Division, LBNL Jean-Luc Popot, Institut de Biologie Physico-Chimique, Paris Crystallization of cytochrome bc 1/amphipol complexes 2000 Carlos Bustamante, Departments of Physics & Molecular and Cell Biology, University of California, Berkeley Malcolm Buckle, Institut Gustave Roussy, Paris RNA polymerase translocation: a comparative study using rapid footprinting, surface plasmon resonance and single molecule methodologies 2000 Gerson Goldhaber, Supernova Cosmology Project, Lawrence Berkeley National Laboratory Reynald Pain, Universités de Paris VI et VII Measurement of the cosmological parameters using Type 1a Supernovae 1999 Mike Levine, Department of Molecular and Cell Biology, University of California, Berkeley Christian sardet, UMR 643 CNRS, Station Zoologique, Villefranche-sur-Mer Searching for muscle determinants in a simple chordate embryo 1999 Krishna K. Niyogi, Department of Plant and Microbial Biology, University of California, Berkeley Michel Havaux, Département d’Ecophysiologie Végétale & Microbiologie, Commissariat à l’Energie Atomique/Cadarache Role of the xanthophylls in the protection of plants from photo-oxidative damage 1999 Hendrik Lenstra, Department of Mathematics, University of California, Berkeley Leila Schneps, Laboratoire de Mathématiques, Université de Franche-Comté, Besançon Galois theory 1998 tito serafini, Department of Molecular and Cell Biology, University of California, Berkeley Alain Chédotal, INSERM Unité 106, Paris Neuronal target recognition and synaptogenesis in the mammalian brain 1999 Maciej Zworski, Department of Mathematics, University of California, Berkeley Frédéric Klopp, Institut Galilée, Université Paris-Nord, Villetaneuse Spectral and scattering theory 1999 Mark Strovink, Department of Physics, University of California, Berkeley Gregorio Bernardi, LPNHE, Universités de Paris VI et VII Search for supersymmetric decays of the top quark 1998 David Robin, Advanced Light Source, Lawrence Berkeley National Laboratory Jasques Laskar, Astronomie et Systèmes Dynamiques, Bureau des Longitudes, CNRS, Paris Application of frequency map analysis to the Advanced Light Source 1998 Daniel Neumark, Department of Chemistry, University of California, Berkeley Benoit Soep, Laboratoire de Photophysique Moléculaire, Université de Paris-Sud, Orsay Time-resolved studies of transition state dynamics 1998 174 France-Berkeley Fund Xiaoye Sherry Li, NERSC, Lawrence Berkeley National Laboratory iain Duff, Parallel Algorithms Project, CERFACS, Toulouse Hybrid ordering algorithms for sparse direct and iterative solvers 1998 Mina J. Bissell, Life Sciences Division, Lawrence Berkeley National Laboratory Edmond Puvion, Institut de Recherche sur le Cancer, Villejuif Regulation of gene expression by nuclear architectural organization: an ultrastructural analysis combining a unique 3-dimensional cell culture system with novel electron microscope techniques 1997 Exact Sciences Thomas Broadhurst, Department of Astronomy, University of California, Berkeley James Bartlett, Observatoire Astronomique de Strasbourg, Université Louis Pasteur Large-scale structure and galaxy formation 1997 William Danchi, Space Sciences Laboratory, University of California, Berkeley Jean Gay, Observatoire de la Côte d’Azur, Nice High angular resolution and mass loss of evolved stars 1997 Ralph Freeman, School of Optometry, University of California, Berkeley Yves Fregnac, Institut Alfred Fessard, Gif-sur-Yvette An integrative regulation of functional connectivity in the developing & adult visual cortex 1997 Melvin Klein, Structural Biology Division, Lawrence Berkeley National Laboratory Jean-Jacques Girerd, Laboratoire de Chimie Inorganique, Université Paris-Sud, Orsay XAS (Xanes and EXAFS) studies coupled to electro-chemistry of chemical models of the catalyticsite of the oxygen evolving center PSII 1997 saul Perlmutter, Center for Particle Astrophysics, Lawrence Berkeley National Laboratory Reynald Pain, LPNHE, Universités Paris VI & VII Measurement of the cosmological parameters Using Type Ia Supernova 1997 Richard Saykally, Department of Chemistry, University of California, Berkeley Claude leforestier, Laboratoire Structure et Dynamique des Systèmes Moléculaires et Solides, Université Montpellier II The dynamics of a nucleotide base hydration 1997 John Canny, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Christian laugier, Institut National de Recherche en Informatique et en Automatique, Grenoble Dynamic simulation for TeleRobotics and medical applications 1996 Forrest S. Mozer, Space Sciences Laboratory, University of California, Berkeley Raymond Pottelette, Centre d’Etudes des Environnements Terrestres et Planétaires, Saint-Maur-des-Fosses Study of acceleration and radiation processes in geospace plasmas 1996 Hans georg Ritter, Nuclear Science Division, Lawrence Berkeley National Laboratory Barbara Erazmus, Laboratoire de Physique Subatomique et des Technologies Associées, Nantes Development of tracking methods for high-energy experiments 1996 Marie-Agnès Deleplanque-Stephens, Nuclear Science Division, Lawrence Berkeley National Laboratory Gilles de France, Centre de Recherches Nucléaires, Université Louis Pasteur, Strasbourg Study of rotating atomic nucleus 1996 Annual Report 2013-2014 175 Exact Sciences Walter Alvarez, Department of Geology and Geophysics, University of California, Berkeley Bernard Beaudoin, CGES Sédimentologie, Ecole des Mines de Paris Environmental consequences of the cretaceous-tertiary boundary event. 1995 Gérard Debreu, Department of Economics, University of California, Berkeley Bernard Cornet, CERSEM, Université de Paris I Mathematical economics 1995 Hiroshi Nikaido, Department of Molecular and Cell Biology, University of California, Berkeley Patrice Courvalin, Institut Pasteur, Paris Role of multi-drug efflux pumps in antibiotic resistance of gram-positive bacteria 1995 John Rhodes, Department of Mathematics, University of California, Berkeley Jean-Eric Pin, LITP/IBP, Université de Paris VII Semigroups, groups, automata and formal languages 1995 Richard Saykally, Department of Chemistry, University of California, Berkeley Claude leforestier, Laboratoire de Chimie Théorétique, Université de Paris-Sud, Orsay Determination of the intermolecular pair potential for water—the universal biological solvent 1995 Eugene D. Commins, Department of Physics, University of California, Berkeley Marie-Anne Bouchiat, Laboratoire Kastler Brossel, CNRS, Paris Violation de la parité dans les atomes: étude de l’interaction électrofaible électron-noyau par des méthodes optiques 1994 Andrew Lange, Department of Physics, University of California, Berkeley François R. Bouchet, Institut d’Astrophysique de Paris, CNRS, Paris Observations and predictions of the cosmological background anisotrophies 1994 Steven G. Louie, Department of Physics, University of California, Berkeley gerard Martinez, Physique, Université Joseph Fourier, Grenoble Electron correlation effects in condensed matter system as the newly discovered fullerene-based materials 1994 Kenneth Ribet, Department of Mathematics, University of California, Berkeley Eva Bayer Fluckiger, Laboratoire de Mathématique, Université de Franche-Comté, Besançon Théorie des nombres 1994 Charles H. Townes, Department of Physics, University of California, Berkeley Jean Lefèvre, Observatoire de la Côte d’Azur, Nice Etude de la perte de masse des étoiles évoluées 1994 176 France-Berkeley Fund Susan J. Muller, Department of Chemical Engineering, University of California, Berkeley Thibaut Divoux, Centre de Recherche Paul Pascal (CNRS - UPR 8641) Testing a generalized stability criterion for viscoelastic flows 2013 Engineering John Harvey, Department of Civil and Environmental Engineering, University of California, Davis Agnès Jullien, IFFSTAR Comparison of use phase methodology and recycling approach for pavement life cycle assessment 2013 Sanjay Kumar, Department of Bioengineering, University of California, Berkeley Manuel Thery, Institut de Recherche en Technologies et Sciences pour le Vivant, CEA, Grenoble Engineering and dissecting the micro-architecture of actomyosin stress fibers 2012 Alexandre Bayen, Center for Information Technology and Research in the Interest of Society, UC Berkeley Paola goatin, INRIA Sophia Antipolis—Méditerranée Optimal traffic flow management with GPS enabled smartphones 2012 Jitendra Malik, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Zaid Harchaoui & Cordelia Schmid, Laboratoire Jean Kuntzmann, LEAR, INRIA Grenoble Large-scale learning for image and video interpretation 2012 Steven Conolly, Department of Bioengineering, University of California, Berkeley Xavier Maître, Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS, Université Paris-Sud Aerosol deposition in the airways with phase-imaging tools for inhaled drug delivery 2012 Vern Paxson, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Renata CruzTeixeira, Laboratoire d’Informatique de Paris 6 Understanding user perspectives of internet performance 2012 Marios Panagiotou, Civil and Environmental Engineering, University of California, Berkeley Stéphane Grange, Université Joseph Fourier, Grenoble I High performance modeling of seismic soil foundation structure interaction in tall buildings 2011 Nicolas Barrière, Space Sciences Laboratory, University of California, Berkeley Pierre Bastie, LSP, Saint-Martin-d’Hères High-quality heavy metal crystals study for the realization of an astronomical gamma-ray telescope 2011 Paulo J. M. Monteiro & Roy W. Carlson, Department of Civil and Environmental Engineering, University of California, Berkeley Pierre Levitz, Laboratoire de Physique de la Matière Condensée, Ecole Polytechnique, Palaiseau Characterization of the nanostructure of calcium silicate hydrates 2010 Bozidar Stojadinovic, Department of Civil and Environmental Engineering, University of California, Berkeley Adnan Ibrahimbegovic, Ecole Normale Supérieure de Cachan, Department of Civil Engineering, Cachan Multi-scale hybrid modeling of failure mechanisms in civil structures under extreme-event loads. 2010 Esmond G. Ng, Computational Research Division, Lawrence Berkeley National Laboratory Luc Giraud, INRIA-Bordeaux Sud Ouest, Toulouse Scalable hybrid solvers for large sparse linear systems of equations on petascale computing architectures 2010 Annual Report 2013-2014 177 Engineering James F. O’Brien, EECS, Computer Science Division, University of California, Berkeley Marie-Paule Cani, INRIA, Grenoble Institute of Technology Real-time simulation methods for interactive surgical simulation and planning 2010 Steven Glaser, Department of Civil and Environmental, Engineering, University of California, Berkeley Térence Bayen, Center of Mathematics, Université de Montpellier 2 Modeling absolute displacements of the human body to quantify diagnoses neuropathology 2010 Sharmila Majumdar, Department of Bioengineering, University of California, Berkeley Roland Chapurlat, Institut National de la Santé et de la Recherche Médicale (INSERM), Lyon Standardization and cross calibration of distal radius and distal tibia bone quality using high resolution peripheral computed tomography scanners. 2009 Philip Marcus, Department of Mechanical Engineering, University of California, Berkeley Patrice Le Gal, Institut de Recherche sur les Phénomènes Hors Equilibre, Université de Provence, Marseille numerical simulations versus experiments on inertial-gravity waves. 2008 Philip Filippou, Department of Civil and Environmental Engineering, University of California, Berkeley Jacky Mazars, Institut Polytechnique de Grenoble, Grenoble High performance modeling of 3D soil-structure interaction under earthquake excitation 2008 Edgar Knobloch, Department of Physics, University of California, Berkeley Alain Bergeon, IMFT, UMR CNRS 5502, Université Paul-Sabatier, Toulouse Localized structures in driven dissipative flows 2008 Karlene Roberts, Haas School of Business, University of California, Berkeley. Erik Hollnagel, Ecole National Supérieure des Mines de Paris, Sophia-Antipolis Research in catastrophic risk management—finally, the twain shall meet 2008 Michael Jordan, Computer Science Division and Department of Statistics, University of California, Berkeley Francis Bach & Jean-Philippe Vert, Centre Morphologie Mathématique, Bioinformatique, Ecole des Mines, Paris Inference and learning in dynamic graphical models, with applications to speech and bio-informatics. 2007 Alexandre Bayen, Department of Civil and Environmental Engineering, University of California, Berkeley Xavier Litrico, CEMAGREF - UMR G-Eau, Montpellier Modeling and data assimilation of semi-automated water distribution canal networks. 2007 Martin Banks, Vision Science, University of California, Berkeley Pascal Mamassian, Institut de Psychologie, Université de Paris 5, Boulogne-Billancourt Time course of adjustment in picture viewing 2006 Roberto Horowitz, Department of Mechanical Engineering, University of California, Berkeley Carlos Canudas-de-Wit, Laboratoire D’Automatique de Grenoble, St Martin d’Hères Towards coordinated and traffic responsive ramp metering strategies. 2005 Costas Grigoropoulos, Mechanical Engineering, University of California, Berkeley Jean-Jacques greffet, Laboratoire EM2C, Ecole Centrale, Chatenay-Malabry Nanoscale heat transfer 2005 178 France-Berkeley Fund Rachel A Segalman, Department of Chemical Engineering, University of California, Berkeley Cyril Brochon, Département de Polymères, Ecole Européenne de Chimie, Strasbourg Nanopatterning and electrical properties of insulated molecular wires 2005 Engineering Paulo J. M. Monteiro, Department of Civil and Environmental Engineering. University of California, Berkeley Olivier P. Coussy, Ecole Nationale des Ponts et Chaussées ENPC, Cité Descartes, Marne-la-Vallée Minimization of the stresses generated by ice formation in concrete 2005 Nitash P. Balsara, Department of Chemical Engineering, University of California, Berkeley Carlos Marques UMR CNRS-ULP 7506, Institut de Physique Strasbourg Self-assembly of monodisperse vesicles: answering the challenge by block copolymer design 2004 Tonya Kuhl, Department Of Chemical Engineering, University of California, Davis Philippe Richetti, CNRS, centre de recherche Blaise Pascal, Université Bordeaux Static and dynamic properties of self-assembled surfactant layers and associative polymers 2004 James Casey, Department of Mechanical Engineering, University of California, Berkeley Gerard Maugin, Laboratoire de Modélisation en Mécanique, Paris VII Application of modern concepts of nonlinear continuum mechanics to some problems of biomechanics 2003 Sam Krucker, Space Sciences Laboratory, University of California, Berkeley Karl-Ludwig Klein, Observatoire de Paris, Section de Meudon New coordinated investigation of accelerated particles at the sun and in the Interplanetary Medium 2003 Filip Filippou, Department of Civil and Environment Engineering, University of California, Berkeley Jacky Mazars, Laboratoires Sols, Solides, Structures, Institut National Polytechnique Grenoble High performance modeling of shear failure of concrete columns under earthquake excitations 2003 Sengupta Raja, Department of Civil and Environment Engineering, University of California, Berkeley Stavros Tripakis, Verimag-CNRS Service networks—intelligent middleware for distributed applications 2003 Ali Shakouri, Department of Electrical Engineering, University of California, Santa Cruz Stefan Dilhaire, CPMOH-Université Bordeaux 1 Caractérisation optique micro-réfrigérateurs par des techniques interférométriques & réflectométriques femtosecnodes 2003 Louise Glass, Plant and Microbial Biology Department, University of California, Berkeley Corrine Clavé, Laboratoire de Génétique Moléculaire des Champignons Comparative analysis of the programmed cell death reaction triggered by nonself recognition genes in two model fungal species 2002 Edward Keller, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley laurent goffard, CNRS Distributed neural control of visual saccades 2002 Pravin Varaiya, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Michel Diaz, Laboratoire d’Automatique et d’Analyse des Systèmes-CNRS, Toulouse End to end transport protocols for the new generation internet 2001 Annual Report 2013-2014 179 Engineering Tonya Kuhl, Department of Chemical Engineering and Material Science, University of California, Davis Carlos Marques, LDFC-Institut de Physique, Université de Strasbourg Binding dynamics of tethered ligand-receptor interactions 2001 Kevin Healy, Bioengineering and Department of Materials Science and Engineering, University of California, Berkeley Véronique Migonney, Institut Galilée, Université de Paris XIII, Villetaneuse Peptide-modified heparin-like copolymers as biomimetic coatings for orthopaedic implants: synthesis, surface characterization, and biological response 2001 Alexandra Navrotsky, Department of Chemical Engineering and Materials Science, University of California, Davis Roger Marchand, Laboratoire «Verres et Céramiques,» Université de Rennes I Thermochemistry of a new class of inorganic nitrogen-containing materials 2001 Stanley Berger, Department of Mechanical Engineering, University of California, Berkeley Francis Cassot, INSERM, Toulouse Numerical and experimental simulations of cerebral blood flow for/and magnetic resonance imaging (MRA and fMRI) 2000 Deborah Hopkins, Engineering Division, Lawrence Berkeley National Laboratory Joëlle Riss, CDGA, Université de Bordeaux I Micromechanics of natural rock fractures under shear stress 2000 Shankar Sastry, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Christian laugier, Projet SHARP, INRIA Rhône-Alpes, Montbonnot Saint-Martin High-fidelity computer simulations of medical procedures 1999 Jonathan Shewchuk, Electrical Engineering and Computer Sciences, University of California, Berkeley Marc Daumas, Laboratoire de l’Informatique du Parallélisme, Ecole Normale Supérieure de Lyon Floating-point multiple precision arithmetic for adaptive computation and elementary functions 1999 Alistair Sinclair, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Claire Kenyon, LRI, Université de Paris-Sud, Orsay Phase transitions and computational complexity 1998 Robert Brayton, Department of Electrical Engineering and Computer Sciences, University of California, Berkeley Dominique Borrione, Laboratoire TIMA, Université Joseph Fourier, Grenoble Multi-standard verification environment for digital systems design 1997 180 France-Berkeley Fund Sophia B. Villas-Boas, Department of Agricultural and Resource Economics, University of California, Berkeley Claire Chambolle, INRA (Institut National de la Recherche Agronomique), Ivry sur Seine The impact of retail mergers on food prices: evidence from France 2013 Déborah Blocker, Department of French, University of California, Berkeley Anne Piéjus, Institut de Recherches sur le patrimoine musical en France New tools and stakes for the study of language and culture in early modern French periodicals: the case of the Mercure Galant 2013 Humanities & Social Sciences Nicholas Paige, Department of French, University of California, Berkeley Guillaume Peureux, Paris 10-Nanterre The “I” before “the Self”: Non-modern uses of the first person in Renaissance and Classical France 2013 Elizabeth Moxon, Advanced Light Source, Lawrence Berkeley National Laboratory Claus Habfast, European Synchrotron Research Facility An international comparative study of best practices in providing high school student access to synchrotrons to conduct outreach experiments 2013 Jason Corburn, School of Public Health and Department of City and Regional Planning, University of California, Berkeley Gérard Salem, Université Paris Ouest, UFR SSA Global urban health: Collaborative research for a new science of the city 2013 Suzanne Guerlac, Department of French, University of California, Berkeley Jean-Pierre Montier, Département de Lettres, Université Rennes 2 Towards a coherently structured development of photoliterary research 2013 Winfried Kudszus, Department of German, University of California, Berkeley Richard Trim, Faculté des Arts, Lettres, Langues et Sciences Humaines, Aix-Marseille Université Metaphor in the political debate of austerity programs 2013 Susan G. Miller, Department of History, University of California, Davis Jocelyne Dakhlia, L’École des Hautes Études en Sciences Sociales, Centre de Recherches Historiques Networking for independence: The Moroccan nationalist movement’s global campaign against French colonialism 2013 Patricia Baquedano-López, Graduate School of Education, University of California, Berkeley Pedro Jose Garcia-Sanchez, Département de Sociologie, Université Paris Ouest Social and political tools of urban cosmopolitanism: The challenge of otherness in distributed cognition and interactivity 2013 Beverly Crawford, Department of Political Science, University of California, Berkeley Denis Rolland, Institut d’Etudes Politiques, Université de Strasbourg Civil society formation in political transitions: the evolution of culture and identity in Latin America, Eastern Europe, and Maghreb/ Machrek 1980-2011 2012 Véronique Munoz-Darde, Department of Philosophy, University of California, Berkeley Lue Foisneau, L’Ecole des Hautes Etudes en Sciences Sociales, Paris A Theory of Justice 40 years on 2012 Annual Report 2013-2014 181 Humanities & Social Sciences Stephanie Lee Mudge, Department of Sociology, University of California, Davis Antoine Vauchez, CNRS: Centre Européen de Sociologie et de Science Politique de l’Université, Université Paris 1 When theory matters: law, economics, and the scholarly production of “Europe”, 1990-2010. 2012 Carla Shapreau, School of Law, University of California, Berkeley Florence Gétreau, Institut de recherche sur le Patrimoine Musical The loss of French musical property during World War II, post-war repatriations, restitutions, and 21st century ramifications 2011 Nikolaos Papazarkadas, Department of Classics, University of California, Berkeley Denis Knoepfler, Collège de France, Paris The epigraphy and history of Boeotia: new finds, new developments 2011 Steven Raphael, Goldman School of Public Policy, University of California, Berkeley Roberto galbiati, Département d’Economie, Sciences Po Paris The emergence of the economic criminologist 2011 Jack Citrin, Governmental Studies, University of California, Berkeley Frédérick Douzet, Institut Français de Géopolitique, Université Paris 8 Urban Frontier in the age of globalization: a comparative study of France and California 2011 Darcy Grimaldo Grigsby, History of Art, University of California, Berkeley Anne Lafont, Institut national d’histoire de l’art, Paris The Artifice of color: representation of Blacks in the French visual arts from the Black Code (1682) to the recognition of the Republic of Haiti(1825) 2011 Lawrence Rosenthal, Center for the Comparative Study of Right-Wing Movements, University of California, Berkeley Eric Darras, Institut d’Etudes Politiques de Toulouse Anger in politics: understanding the emergence of the Tea Party Movement 2011 Keith Johnson, Department of Linguistics, University of California, Berkeley Elsa Spinelli, Laboratoire de Psychologie et NeuroCognition, Université Pierre Mendès France, Grenoble 2 Variability and lexical representations 2010 Nancy Lee Peluso, Department of Environmental Science, Policy, and Management, University of California, Berkeley Gabrielle Bouleau, Cemagref, UMR G-EAU, Montpellier Risk societies and governance in Mediterranean Climate deltas flood-prone waterscapes 2010 Charles Altieri, Department of English, University of California, Berkeley Isabelle Alfandary and Axel Nesme, Département d’Etudes du Monde Anglophone, Université Lumière-Lyon 2 Transatlantic transactions: French theory and twentieth century American poetry 2009 Margaret Conkey, Anthropology, University of California, Berkeley Sébastein Lacombe, Université de Toulouse-le Mirail, Toulouse Open air paleolithic occupations on the north slope of the Central Pyrénées: inventory and analysis of a rare and significant collection of prehistoric artifacts 2009 182 France-Berkeley Fund Ronnie Lipschutz, Department of Politics, University of California, Santa Cruz Béatrice Hibou, Centre d’études et de recherche internationales, Sciences Po, Paris The public-private hybridization of the 21st century state 2009 sofia Berto Villas-Boas, Agricultural and Resource Economics, University of California, Berkeley Céline Bonnet and Pierre Dubois, GREMAQ, Université de Toulouse Non linear wholesale pricing and retail pass-through: evidence from counterfactual experiments 2009 Humanities & Social Sciences AnnaLee Saxenian, School of Information, University of California, Berkeley Hervé Dumez, Centre de Recherche en Gestion, Ecole Polytechnique, Paris Making a mark: French trademarking practice and its long-term influence 2009 William J. Jagust, Public Health and Neuroscience, UC Berkeley and Lawrence Berkeley National Laboratory Michel Isingrini, Université François Rabelais, Centre de Recherche sur la Cognition, Tours Brain basis of metamemory in aging 2008 Niek Veldhuis, Department of Near Eastern studies, University of California, Berkeley Francis Joannès, Département d’Histoire, Université de Paris 1 Panthéon-Sorbonne, Paris Hellenistic Babylonia: texts, iconography & names 2008 Stefano Varesse, Department of Native American Studies, University of California, Davis Philippe Descola, Laboratoire d’Anthropologie Sociale, Collège de France, Paris All our relatives: indigenous cosmocentric epistemologies in dialogue 2008 Larry Hyman, Department of Linguistics, University of California, Berkeley Jean-Marie Hombert, Dynamique du Langage, Institut des Sciences de l’Homme, Lyon Towards a re-evaluation of the history of the peopling and languages of Sub-Saharan Africa 2008 Ravi Rajan, Deborah Letourneau, Department of Environmental Studies, University of California, Santa Cruz Christophe Bonneuil, Centre Koyré d’Histoire des Sciences et des techniques-MNHN CP 25, Paris Mobilizing science for public policy on ecological risks of genetically engineered organisims 2008 Christine Hastorf, Department of Anthropology, University of California, Berkeley Gilles Touchais, Département d’Archéologie et Histoire de l’Art, Université de Paris 1 Panthéon-Sorbonne, Paris Food archaeology in Argolid (Greece): cross-correlation between isotopic analysis and macroscopic observation of the dental remains 2008 Brian A. Catlos, Department of History, University of California, Santa Cruz Damien Coulon, UFR des Sciences Historiques, Université Marc-Bloch, Strasbourg Inter-confessional relations and trade in the medieval Mediterranean 2007 Bruce E. Cain, Institute of Governmental Studies, University of California, Berkeley Frédérick Douzet, Institut Français de Géopolitique, Université de Paris 8, Saint Denis Immigration, segregation and urban tension in France and California. 2007 Ann Banfield, College of Letters and Science, University of California, Berkeley Gilles Philippe, Université Stendhal, Grenoble Linguistics and the language arts: developing new research programs 2007 Annual Report 2013-2014 183 Humanities & Social Sciences Richard Kern, French Department, University of California, Berkeley Christine Develotte, Ecole Normale Supérieure, Lettres et Sciences Humaines, Lyon Rethinking language teaching in the digital age: French and American perspectives on technology and pedagogy 2007 Barry Eichengreen, Department of Economics, University of California, Berkeley Marc Flandreau, Department of Economics, Institut d’Etudes Politiques de Paris International currencies in theory and history 2006 Wen-hsin Yeh, Department of History, University of California, Berkeley Christian Henriot, Institut d’Asie Orientale (UMR5062), Ecole Normale Supérieure, Lyon Visual documents in the study of modern China 2005 Charles J. Fillmore, Department of Linguistics, University of California, Berkeley Laurent Romary, Laboratoire de Recherche en Informatique et Applications, Université Nancy 2,Vandoeuvre-lès-Nancy Putting semantics into the trees: Towards a French FrameNet 2005 Dan I. Slobin, Department of Psychology University of California, Berkeley Maarten Lemmens, Université Lille 3, U.F.R. Angellier, Villeneuve d’Ascq Experimental investigations into language typology 2005 Jonathan Beecher, History Department, University of California, Santa Cruz Jean-Claude Zancarini, ENS Lettres & Sciences Humaines, Lyon The reception of social theories in the 19th century in France and the United States 2005 Beshara Doumani, Department of History, University of California, Berkeley Randi Deguilhem, CNRS, IREMAM-MMSH, Aix-en-Provence Who controlled the Ottoman legal system? Professions and power configurations in the Imperial and Provincial Courts (18th-20th centuries.) 2005 Robert Knapp, Department of Classics, University of California, Berkeley Vincent Jolivet, Ecole Française de Rome, CNRS Rome Etruscan Sarcophagi from Musarna in the Berkeley Museum 2004 Dominic Massaro, Department of Psychology University of California, Santa Cruz Yves Laprie, LORIA CNRS UMR 7503, 54600 Villers-les-Nancy Improving the labial coarticulation in talking heads 2004 Claire Kramsch, German Department, University of California, Berkeley Genevieve Zarate, Institut National des langues et Civilisations Orientales Language, culture, identtity in secondary/foreign language learning and teaching: an interdisciplinary workshop 2003 Patrick V. Kirch, Anthropology Department, University of California, Berkeley Jean-Louis Rallu, Institut National d’Etudes Démographiques Paris Long term demographic evolution in French Polynesia: an interdisciplinary approach 2003 184 France-Berkeley Fund Agnes Gellen, Department of Philosophy, University of California, Berkeley Elise Domenach, Department of Philosophy, Université de Picardie, Jules Verne Kant’s trans-Atlantic legacy of skepticism 2002 Larry Hyman, Department of Linguistics, University of California, Berkeley Gerard Phillipson, INALCO Paris, en délégation au Laboratoire Dynamique du Langage Linguistic philogenies in the Bantu domain 2002 Humanities & Social Sciences Jennifer Johnson-Hanks, Department of Demography, University of California, Berkeley Nathalie Picard-Tortorici, THEMA, Université de Cergy-Pontoise New approaches to fertility in West Africa 2002 Tyler Stovall, Department of History, University of California, Berkeley Michel Giraud, CNRS/Université des Antilles et de la Guyane Strangers at home: Caribbean immigrants in France and in the United States 2002 Martin Wachs, Institute of Transportation Studies, City and Regional Planning, University of California, Berkeley Cynthia Ghorra-Gobin, CNRS-Paris, National Scientific Research Center Public services and organizational innovations: A French and American perspective in the transit system 2002 Edmund Campion, Department of Music Composer in Residence, CNMAT Francois Paris, Centre International de Recherche Musicale CIRM/CNMAT Collaboration 2002 Ethan Ligon, Department of Agricultural and Resource Economics, University of California, Berkeley Pierre Dubois, UFR d’Economie et de Sociologie Rurales, INRA, Toulouse Microeconomic theory and empirical studies of intra-household behavior in developing countries 2001 Bronwyn Hall Department of Economics, University of California, Berkeley Jacques Mairesse, INSEE-CREST, Malakoff Economics, history and law of intellectual property: proposal for a Franco-American conference 2001 David Hult, Department of French, University of California, Berkeley Danielle Bohler, Langue et littérature françaises du Moyen Age, Université Michel de Montaigne Bordeaux III La Culture du Livre: naissance et transformations du lecteur depuis la fin du Moyen Age jusqu’au seuil de la modernité 2001 Mark Franko, Department of Theater Arts, University of California, Santa Cruz Carlo Severi, Laboratoire d’Anthropologie sociale, EHESS, Collège de France Symbolic actions: ritual, dance, theater, art. 2001 Sharon Daniel, Department of Film and Digital Media, University of California, Santa Cruz Karen O’Rourke, UFR d’Arts Plastiques et Sciences de l’Art, Université de Paris I Mapping the database: designing and building interdisciplinary, non-hierarchical, dynamically evolving art/information systems 2001 Wen-hsin Yeh, Department of History, University of California, Berkeley Christian Henriot, Institut d’Asie Orientale, Université Lumière Lyon II Shanghai in images: a historical photographic database (1840-1949) 2000 Annual Report 2013-2014 185 Humanities & Social Sciences John Radke, Geographic Information Science Center, University of California, Berkeley Didier Josselin, Laboratoire THEMA, Université de Franche-Comté, Besançon A boundary generation system for landscape characterization 2000 David Vogel, Haas School of Business, University of California, Berkeley Jabril Bensédrine, Economie et Gestion, Université de Marne-la-Vallée French and American Perspectives on genetically-engineered food: institutional convergence and divergence as sources of cooperation and dispute 2000 Nicholas Paige, Department of French, University of California, Berkeley Christian Biet, Institut d’Etudes théâtrales, Université de Paris X, Nanterre The literature of law: judicial and economic culture, 1550-1789 1999 Neil Fligstein, Department of Sociology, University of California, Berkeley Rémi Lenoir, Sociologie, Université de Paris I; CSEC-CSE/EHESS, Paris French field theory and American New Institutionalism: building theoretical bridges 1999 Patrick V. Kirch, Department of Anthropology, University of California, Berkeley Eric Conte, Université Française du Pacifique, Tahiti Prehistoric Polynesian voyaging and island colonization: new archaeological perspectives 1999 David Wessel, The Center for New Music and Audio Technologies, University of California, Berkeley Xavier Rodet, Institut de Recherche et Coordination Acoustique/Musique, Paris Gestural control of musical sound synthesis 1998 Gordon Rausser, College of Natural Resources, University of California, Berkeley Patrick Rio, UFR d’Economie et de Sociologie Rurales, INRA, Montpellier Multilateral negotiations over water management in France and California 1998 Sharon Marcus, Department of English, University of California, Berkeley Karen Bowie, Ecole d’Architecture de Paris Val-de-Marne, Charenton-le-Pont Forms of urban life in Paris, 1815-1851 1998 Andrew Barshay, Department of History, University of California, Berkeley Jean-François Sabouret, Etudes Japonaises, Centre National de la Recherche Scientifique, Paris 1968: Events and legacies 1998 Paula Fass, Department of History, University of California, Berkeley Agnes Fine, UFR d’Historia, Université de Toulouse Le Mirail A comparative analysis of ‘new families’ in France and the United States 1997 David Stronach, Department of Near Eastern Studies, University of California, Berkeley Frantz Grenet, Ecole Normale Supérieure, Paris Workshop on strategies for joint archaeological excavation and research in Central Asia 1997 Michael Watts, Institute of International Studies, University of California, Berkeley Gilles Allaire, UFR d’Economie et de Sociologie Rurales, INRA, Castanet-Tolosan Systems & trajectories of innovation: institutions, technology & conventions in agriculture regulation 1997 186 France-Berkeley Fund Paolo Mancosu, Department of Philosophy, University of California, Berkeley Hourya Sinaceur, Institut d’Histoire et Philosophie des Sciences et des Techniques, Université Paris I Bernard Bolzano: philosophy of logic and mathematics 1997 Susanna Elm, Department of History, University of California, Berkeley Eric Rebillard, Ecole Française de Rome, Rome Boundaries of discourse: establishing, maintaining and challenging ‘Orthodoxy’ in the history of Christianity 1996 Humanities & Social Sciences Mariane C. Ferme, Department of Anthropology, University of California, Berkeley Jean-Loup Amselle, Centre d’Etudes Africaines, EHESS, Paris Imperialism and identity: remapping the cultural politics of representation 1996 Sylvia Guendelman, School of Public Health, University of California, Berkeley Gérard Bréart, INSERM Unité 149, Paris A world on the move: a comparative look at the birth outcomes of immigrant women in France, Belgium and the US 1996 Larry Karp, Department of Agricultural and Resource Sciences, University of California, Berkeley Thierry Paul, GREQAM-LEQAM, Université d’Aix-Marseille II, Les Milles Government policy and labor market imperfections 1996 Margaret W. Conkey, Department of Anthropology, University of California, Berkeley Valerie Andrieux, Laboratoire de Botanique Historique et Palynologie, Faculté des Sciences, Saint Jérôme Marseille Explorations into the social geography and paleoenvironments of Late Ice Age Peoples of the French Midi-Pyrenees (Ariège / Haute Garonne) 1995 Ervin Hafter, Department of Psychology, University of California, Berkeley Anne-Marie Bonnel, CNRS-Laboratoire de Neurosciences Cognitives Marseille Study of deficit in attention in the diagnostic of onset psychosis 1995 Laurent Mayali, Robbins Collection, School of Law, University of California, Berkeley Bernard Durand, Institut d’Histoire du Droit, URA 966 CNRS, Université de Montpellier I Délinquance, justice et doctrine pénale ecclésiastique 1995 Gene I. Rochlin, Institute of Governmental Studies, University of California, Berkeley Werner Ackermann, Centre de Sociologie des Organisations/CNRS, Paris Cross-national studies of the sociology of organizations: fostering cooperation on methodological coordination and promoting observational inter-comparisons 1995 Loic J. D. Wacquant, Department of Sociology, University of California, Berkeley Pierre Bourdieu, Sociologie, Collège de France, Paris Actualité et Modernité de la Pensée de Marcel Mauss` 1995 Larry M. Hyman, Department of Linguistics, University of California, Berkeley Jean-Marie Hombert, Linguistique, Université Lumière Lyon II Language as a key to history 1994 Annual Report 2013-2014 187 Humanities & Social Sciences Tim D. White, Department of Integrative Biology, University of California, Berkeley Raymonde Bonnefille, Laboratoire de Géologie du Quaternaire, CNRS, Marseille Habitat of the earliest human ancestors 1995 Yale M. Braunstein, School of Library and Information Sciences, University of California, Berkeley Anne Mayère, Centre d’Etudes et de Recherche en Sciences de l’Information, ENSSIB, Villeurbanne User fees for government information in France and the United States: analysis of current policies and practices 1994 Suzanne Scotchmer, School of Public Policy, University of California, Berkeley Jacques-Francois Thisse, CERAS, Université de Paris I Cumulative innovation and the patent law 1994 188 France-Berkeley Fund Map Sources (all maps presumed to be public domain): Cover & headings: http://upload.wikimedia.org/wikipedia/commons/0/08/1780_Raynal_and_ Bonne_Map_of_the_Two_Hemispheres_-_Geographicus_-_Hemispheres-bonne-1780.jpg Rigobert Bonne [Public domain], via Wikimedia Commons; p.1, 2-3, 5, 22-23, 91, 126, 157; 189: Library of Congress, Geography and Map Division; p. 7, 135, 138, 144, 146, 148, 152, 154, 156: http://www.tablespace.net/ (William Favorite); p. 17: “FraMauroDetailedMap” by Piero Falchetta - “The Fra Mauro map”. Licensed under Public domain via Wikimedia Commons; p. 24: https://www.flickr.com/photos/normanbleventhalmapcenter/14049836755/; p. 127: « Le comté de Nice et Oneille » par Blaeu — Atlas Maior de Joan Blaeu;. Sous licence Public domain via Wikimedia Commons; p. 142: From Topographical Map of Central California Together with a Part of Nevada, C.F. Hoffman, Principal Topographer, State Geological Survey of California, 1873. (Eric Fisher) https://www.flickr.com/photos/walkingsf/7100202081/; p. 150: « Plan de 1660 - Grenoble » par Inconnu — bibliothèque municipale de Grenoble. Sous licence Public domain via Wikimedia Commons; p. 188: « Marseille - vieille carte » par Inconnu — Scanné de Coureurs des mers, Poivre d’Arvor. Sous licence Public domain via Wikimedia Commons. Photos from 20th Anniversary Celebration by Peg Skorpinski, John Ringhofer, and Andrea Davis.
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