Jointly$organized$with$ 3rd$Interna*onal$TB/Mee*ng$ INHALED(THERAPIES( FOR(TUBERCULOSIS(AND( OTHER(INFECTIOUS(DISEASES( October(14:16,(2015( Parma,(Italy( hEp://www.tefarco.it/TB2015( ScienNﬁc(Organizing(CommiEee( Ruggero$BeEni,$University$of$Parma$/$BioPharmanet/Tec$(IT)$ Francesca$BuEni,$University$of$Parma$(IT)$ Gaia$Colombo,$University$of$Ferrara$(IT)$ Paolo$Colombo,$University$of$Parma$(IT)$ Anthony$Hickey,$RTI$Interna*onal$(US)$ Amit$Misra,$(Central$Drug$Research$Ins*tute,$IN)$ Alessandra$Rossi,$University$of$Parma$(IT)$ Fabio$Sonvico,$University$of$Parma$(IT)$ Invited(Speakers( • Karim$Amighi$(U$Bruxelles,$BE)$ • Jason$McConville$(U$New$Mexico,$US)$ • Francesca$BuEni$(U$Parma,$IT)$ • Helen$McShane$(Oxford$University,$UK)$ • Alfredo$CheIa$(U$Parma,$IT)$ • Heribert$Mentzel$(Pari$GmbH,$DE)$ • Elias$FaIal$(U$Paris$Sud$XI,$FR)$ • Amit$Misra$(Central$Drug$Research$Ins*tute,$IN)$ • Ben$Forbes$(King’s$College,$UK)$ • Pavan$MuEl$(U$New$Mexico,$US)$ • Bernard$Fourie$(U$Pretoria,$ZA)$ • Edward$Nardell$(Harvard,$US)$ • Erik$Frijilink$(U$Groningen,$NL)$ • Ann$Rawkins$(Public$Health$England,$UK)$ • Lucila$Garcia/Contreras$(U$Oklahoma,$US)$ • Philippe$Rogueda$(Chemo,$ES)$ • Igor$Gonda$(Aradigm$Corpora*on,$US)$ • Larry$Schlesinger$(Ohio$State$U,$US)$ • Mercedes$Gonzales/Juarrero$(CSU,$US)$ • Aurélie$Schoubben$(U$Perugia,$IT)$ • Anthony$Hickey$(RTI$Interna*onal$,$US)$ • Daniela$Traini$(Woolcock$Ins*tute,$AU)$ • Joseph$Keane$(Trinity$College,$IE)$ • Reinhard$Vehring$(U$Alberta,$CA)$ • Jenny$Ka/Wing$Lam$(Hong$Kong$U,$HK)$ • Robert$Williams$(U$Texas$Aus*n,$US)$ • Kimiko$Makino$(Tokyo$U$of$Science,$JP)$$ Rapporteurs( Gerrit$Borchard$(U$Geneva,$CH),$Hak/Kim$Chan$(U$Sydney,$AU),$Anne$de$Boer$(U$Groningen,$ NL),$Vojo$Dere*c$(U$New$Mexico,$US),$Norio$Doi$(RIT,$JP),$Maurizio$Ricci$(U$Perugia,$IT),$Brian$ Robertson$(Imperial$College,$UK),$Peter$Stewart$(Monash$U,$AU),$ $Hiroshi$Terada$(Niigata$U,$ JP),$MaIeo$Zignol$(WHO,$CH)$ Inhaled(Therapies(for(Tuberculosis(and(InfecNous(Diseases( Aerosol( therapy( for$ the$ treatment$ of$ tuberculosis$ and$ pulmonary$ infec*ons$ is$ growing$ due$ to$ the$ accessibility$ of$ local$ targe*ng,$ the$ complexi*es$ of$ treatment$ by$ conven*onal$ routes$ and$ the$ impressive$ advancement$ of$ inhala*on$ technology.$ The$ understanding$ of$ the$ molecular( and( cellular( mechanisms,$ local$ immunology$ and$ pathophysiology$ of$ tuberculosis$ dictates$ the$ strategies$ for$ delivering$ selected$ drugs$ and$ vaccines$ to$ the$ site$ of$ infec*on$ for$ successful$ outcomes$ in$ this$ important$ therapeu*c$ endeavor.$ Diﬃcul*es$ may$ be$ experienced$ with$ respect$ to$ delivery$ of$ two$ or$ three$ potent$ but$ poorly$ bioavailable$drugs,$barriers$to$the$treatment$due$to$co/infec*on,$impact$of$ pathophysiology$ factors$ on$ the$ fate$ of$ inhaled( medicines( or$ mul*drug$ resistance.$ Due$ to$ the$ long$ dura*on$ of$ therapy$ and$ drug$ combina*on$ required,$ trea*ng$ TB$ by$ inhala*on$ could$ teach$ how$ to$ translate$ the$ therapy$ outcomes$ to$ other$ infec*ons$ prevalent$ in$ cys*c$ ﬁbrosis,$ bronchiectasis$or$COPD.$$ $ This( meeNng( focuses( on( tuberculosis( and( intends( from( TB( therapy( to( translate( products,( technologies( and( procedures( for( eﬃciently( treaNng( pulmonary(infecNve(diseases.( Session( TOPICS( 1$ Wednesday$abernoon$ Oct.$14th,$2015$ Tuberculosis:$mechanism$of$mucosal$ immunity$and$pathophysiology( 2$ Thursday$morning$ Oct.$15th,$2015$ Inhaled$therapies:$small$molecules,$pep*des,$ nucleic$acids,$vaccines,$phages$ 3$ Thursday$abernoon$ Oct.$15th,$2015$ Inhaled$therapies:$non/clinical$and$clinical$ evalua*ons$ 4$ Friday$all/day$ Oct.$16th,$2015$ Formula*ons$and$devices$for$tuberculosis$ and$other$pulmonary$infec*ons( MeeNng(Venue( STARHOTELS$Du$Parc$ Viale$Piacenza,$12/C$ 43125$Parma$(Italy)$ [email protected]$$ Tel.$+39$0521$292929$ Fax$+39$0521$292828$ MeeNng(Secretariat( Dr.$Elena$Vidale$ TEFARCO$Innova,$c/o$Department$of$Pharmacy$ Viale$delle$Scienze$27A$/$Campus$ 43124$Parma$(Italy)$ E/[email protected]$ ScienNﬁc(Posters( Scien*sts$are$invited$to$submit$contribu*ons$on$related$topics.$Contributed$ papers$will$be$selected$by$the$Scien*ﬁc$CommiIee$and$presented$in$form$ of$ posters.$ Papers$ must$ be$ submiIed$ according$ to$ the$ instruc*ons$ provided$in$the$Mee*ng$webpage$(hIp://www.tefarco.it/TB2015).$ Deadline(for(paper(submission:(May(31st,(2015( RegistraNon(Fees( Full(Conference( BEFORE(June(30th,(2015( AFTER(June(30th,(2015( Student$ 150$$€$ 200$€$ Academic$ 300$$€$ 400$€$ Industry$ 450$$€$ 550$€$