AU TITRE BELGE 2013-2014 PROFESSEUR MICHEL GEORGES I N V I TAT I O N CHAIRE FRANCQUI Lis-moi ton génome, je te dirai qui tu es Le professeur Vincent BLONDEL, recteur de l’Université catholique de Louvain, le professeur Jacques MELIN, vice-recteur du Secteur des sciences de la santé, le professeur Dominique VANPEE, doyen de la Faculté de médecine et médecine dentaire, le professeur Frédéric LEMAIGRE, président de l’Institut de Duve, ont l’honneur de vous inviter le mardi 4 novembre 2014 à 17h à la leçon que donnera le professeur Michel GEORGES du GIGA-R et de la Faculté de médecine vétérinaire de l’Université de Liège, en qualité de titulaire de la Chaire Francqui au titre belge. La leçon inaugurale sera suivie d’une réception. Adresse du jour : Auditoire Maisin - Faculté de médecine - avenue E. Mounier 51 - 1200 Bruxelles Leçon inaugurale • Mardi 4 novembre 2014 à 17h Read me your genome, I’ll tell you who you are Auditoire Maisin Leçons ordinaires • Mercredi 12 novembre 2014 à 17h Selection in action: the genetic saga of the double- • An NGS-based reverse genetic screen reveals muscled Belgian Blue Cattle breed embryonic lethals compromising fertility • Auditoire central B Auditoire Maisin Mercredi 19 novembre 2014 à 17h Phenotypic effects of polymorphic miRNA-mediated • gene regulation: lessons from sheep inherited predisposition to inflammatory bowel disease • Auditoire Maisin Auditoire Maisin Mardi 2 décembre 2014 à 17h Mardi 9 décembre 2014 à 17h Identifying causative variants and genes underlying Mardi 25 novembre 2014 à 17h Studying coat color in animals reveals a novel CNV- generating mechanism: serial translocation via circular intermediates underlies color sidedness Auditoire Maisin Adresse : Auditoires centraux - avenue E. Mounier 51 - 1200 Bruxelles http://uclouvain.be/68220.html Michel Georges is Professor in Genetics and Genomics at the Faculty of Veterinary Medicine of the University of Liège. He heads the Unit of Genetics of the GIGA Research Institute in the same university. Georges was born in Antwerp in 1959. He obtained his DVM degree at the University of Liège in 1983, followed by a degree in Molecular Biology at the Free University of Brussels in 1985. From 1985 to 1988 he worked in the laboratories of Gilbert Vassart at the Free University of Brussels and Roger Hanset at the University of Liège. He obtained his habilitation from the University of Liège in 1991. From 1989 to 1993 he was senior scientist, then director of research at Genmark Inc. and adjunct professor in the Department of Human Genetics in Salt Lake City, Utah. Since 1994 he has been heading the Unit of Animal Genomics at the University of Liège. He played an instrumental role in establishing the GIGA Research Institute. Georges was awarded the Wolf Prize in Agriculture in 2007, and the Francqui Prize in Biomedical Sciences in 2008. He is a member of the National Academy of Sciences (USA). Prof. Georges devoted his scientific carrier to the development and use of genomic tools for the identification of genes and mutations underlying complex traits of agronomic and medical importance. He participated in the very first genome scans for QTL in the rat, and then conducted many such scans in livestock. His laboratory is known for pushing these studies down to the identification of causative genes and variants (or QTN). Georges’ team has discovered polar overdominance, identified the “double-muscling” gene, identified several regulatory QTN including some that perturb miRNA-mediated gene regulation, and discovered a novel CNV generating mechanism underlying the inheritance of colour-sidedness. He made important contributions to the “genomic selection (GS) revolution” in livestock. More recently, Georges’ team has been involved in the genetics of inflammatory bowel disease and has contributed to the identification of novel risk loci, genes and variants. Curriculum Vitae Contact: [email protected]
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