3rd LIND seminar - Getting connected Friday, December 5, 2014 LamotTM, Mechelen POSTER PRESENTATIONS – SESSION 1 AT 11:15 – 13:15 (listed in alphabetical order by last name of presenting author) 1. The quest for an Alzheimer disease therapeutic nanobody specific for PSEN1/APH1B gammasecretase Acx H. 2. Long-term-depression and depotentiation are sensitive tools to detect synaptic impairments in the APP/PS1-21 and THY-tau-22 mouse models of Alzheimer’s disease Ahmed T. 3. Pharmacogenetics of lithium and valproate in Drosophila melanogaster Bekelaar K. 4. The Alzheimer disease protective mutation A2T modulates Aβ generation and aggregation Benilova I. 5. Pharmacological inhibition of HDAC6 is beneficial in mutant Gars-induced CMT2 mouse model Benoy V. 6. Visual number beats abstract numerosity: format-dependent neural representations of numbers in the human parietal cortex Bulthé J. 7. Strain-dependent deficits in social and contextual discrimination learning following unpredictable chronic mild stress Callaerts-Vegh Z. 8. Aβ production in the brains of Familial Alzheimer disease patients Chávez-Gutiérrez L. 9. Ictal perfusion changes during macaque amygdala kindling and effective connectivity of the kindled amygdala Cleeren E. 10. Development and Differentiation of the Drosophila Insulin-Producing Neurons Clements Jason 11. The role of ephrin signaling in neural repair following ischemic stroke De Boer A. 12. Cerebellar degeneration in peroxisomal multifunctional protein-2 (MFP2) deficiency De Munter S. 13. Electrical stimulation of the cavity wall of motor cortex lesions: effect on motor behavior in rats Deprez M. 14. Investigating possible recovery of chemotherapy-induced structural changes in cerebral white matter and its relation with cognitive functioning in breast cancer patients Deprez S. 15. Distinct subcellular localization of the neuronal marker HuC/D reveals hypoxia-induced damage in enteric neurons Desmet A.-S. 16. Fast in vivo MRI to determine demyelination: validation in a myelin basic protein mutant mouse Dresselaers T. 17. Role of locus coeruleus in novelty processing Esquivelzeta J. 18. Cell autonomous regulation of cortical circuitry via Aph1b-γ-secretase/Neuregulin 1 signalling Fazzari P. 19. Automated neuronal counting in retinal whole mounts using ImageJ Geeraerts E. 20. Genetic risk factors are associated with cerebrospinal fluid measures in multiple sclerosis Goris A. 21. Towards longitudinal volumetry in a mouse model of tauopathy using atlas-based MRI methods Govaerts K. 22. De novo and recurrent missense mutations in the regulatory B56δ and scaffolding Aα subunits of protein phosphatase 2A cause a syndromic form of intellectual disability Haesen D. 23. A Catalog of Hemizygous Variation in 127 22q11 Deletion Patients Hestand M.S. 24. Burden of risk variants correlates with phenotype of multiple sclerosis Hilven K. 25. Lipid binding at the N-terminus of ATP13A2 represents a key to unlock its function in neurological disorders Holemans T. 26. It's all in the wrist: Neural substrates of selectively maintained expert mechanisms in older musicians Krampe R.T. 27. How inhibition regulates functional recovery in mouse visual cortex after monocular enucleation Laramée M.E. 28. Prefrontal cortex lesions modify spatial memory and hippocampal long-term potentiation Latif-Hernandez A. 29. Matrix metalloproteinases (MMPs) as promising regulators of axonal regrowth in adult zebrafish optic nerve regeneration Lemmens K. 30. Evaluation of the WGA tracer technology in different brain areas Libbrecht S. 31. Optogenetic reinforcement of long-term potentiation in acute hippocampal slices Sabanov V. 3rd LIND seminar - Getting connected Friday, December 5, 2014 LamotTM, Mechelen POSTER PRESENTATIONS – SESSION 2 AT 14:00 – 15:30 (listed in alphabetical order by last name of presenting author) 32. Rescue of impaired late-phase LTD in a tau transgenic mouse model Ahmed T. 33. The immunological architecture of multiple sclerosis and treatment Goris A. 34. Differential involvement of group I mGluRs in long-term potentiation and depotentiation in the hippocampal CA1-region Latif-Hernandez A. 35. LRRK2 kinase inhibition reduces endogenous LRRK2 protein levels in vivo Lobbestael E. 36. Electrical stimulation in the bed nucleus of the stria terminalis in a rat model of anxiety Luyck K. 37. Role of ghrelin in differential brain responses to continuous intra-gastric nutrient infusion and gastric balloon distension: a H215O-PET study Ly H.G. 38. Development and optimization of an alpha-synuclein split-reporter complementation assay for drug discovery purposes Michiels A. 39. There is no Sweet Escape from Social Pain: Glucose Does Not Attenuate the Effects of Ostracism Miller H.C. 40. The neural mechanism for stimulus novelty detection Mutlu K. 41. Neural correlates of the effect of cueing on writing skills in Parkinson’s disease Nackaerts E. 42. Analysis of the role of dopamine in novelty processing Noutel J. 43. Cystine/glutamate antiporter or System Xc- deficiency affects cross-modal plasticity in the visual cortex of the mouse: a glutamatergic study Nys J. 44. Characterization of neuroinflammation in a lipopolysaccharide model using PET, MRI and immunohistochemistry Ory D. 45. Dissecting the role of DJ-1 in adult neurogenesis by modulation of endogenous neural stem cells with lentiviral vectors Osório L. 46. Role of Eph-Ephrin system in Amyotrophic Lateral Sclerosis and Alzheimer’s disease Poppe L. 47. TRPM4 is a key mediator for NMDA-receptor dependent hippocampal LTP but not LTD Sabanov V. 48. A phosphorylation-dependent sorting motif restricts presenilin 2 to late endosomes/lysosomes providing a basis for substrate specificity Sannerud R. 49. Re-evaluating the role of GSK3β in hippocampal synaptic plasticity using a genetic approach Schreurs A. 50. The role of miRNAs in Alzheimer-related memory dysfunction Sierksma A. 51. Mutations in SLC25A, a mitochondrial carrier protein, protect against systemic Manganeseinduced neuronal toxicity Slabbaert J. 52. Flexible system for genetic manipulation of astrocytes Slezak M. 53. Neurobeachin, an autism spectrum disorder candidate gene, is expressed in the nucleus and affects Notch-mediated transcription Tuand K. 54. ALS-causing mutations and rare variant A90V in TDP-43 behave as loss-of-function alleles in Drosophila Vanden Broeck L. 55. Viral vectors as a tool to express optogenetics-related proteins in the brain Van den Haute C. 56. The effects of reversible inactivation of the Caudal Intraparietal area on behavior and on the cortical network involved in the analysis of depth structure studied with awake monkey fMRI Van Dromme I.C. 57. The impact of aging on the regenerative potential of the zebrafish Van Houcke J. 58. Hearing modulates male-male aggression in Drosophila Versteven M. 59. A Nanobody-based approach to investigate the structure-function of γ-secretase Veugelen S. 60. Altered structure and functionality of the visual cortex in MMP-3 deficient mice Vreysen S. 61. Association between cerebral cannabinoid type 1 receptor availability and body mass index in homeostatic and reward regions in patients with food intake disorders and healthy controls Weltens N. 62. Glial Notch regulates Drosophila behavior by maintaining adult brain homeostasis Zwarts L.