物質生命理工学科主催コロキウム"Creative Avenues to

2016年度物質生命理工学科コロキウム
上智大学理工学部物質生命理工学科主催
理工学部・理工学振興会共催
Creative Avenues to Understanding Biology
via Applied Total Synthesis and Chemical
Mimicry
Dr. Martin J. Lear
Senior Lecturer
School of Chemistry
University of Lincoln
日時：2017年1月26日（木） 15:15-16:30
場所：L-821（図書館内会議室）
学外の方の聴講歓迎・申込不要・参加無料
問い合わせ：臼杵豊展 t-usuki[at]sophia.ac.jp
Natural products provide a unique platform to understanding biological processes. They
often have innate and unforeseen biological activities. Through chemical synthesis and
suitable modification of natural products, aberrant disease states of cells can be explored
and exploited therapeutically. Also, disease-associated pathways and biomolecules can be
unveiled for the first time. In this presentation, a series of total synthesis cases studies will
be presented in our continuing endeavors to explore and understand malaria, tuberculosis,
drug resistance, and cancer.
Martin J. Lear (ーアリ・ンィテーマ), b. April 2nd 1970 (British, UK), University of Glasgow, Scotland (B.Sc., 1991; Ph.D.,
1996). Dr. Lear has research interests in organic chemistry, total synthesis, molecular imaging, and the bio-targeting
of natural products. Since April 2015, he has been a Senior Lecturer at the University of Lincoln (UK) and is an
Adjunct Professor at Tohoku University. During January 2013 to March 2015, he was an Associate Professor at Tohoku
University with Yujiro Hayashi and Masahiro Hirama (Sendai, Japan). During 2005 to 2012, he was a Lecturer and
core-member of the Medicinal Chemistry Group at the National University of Singapore (NUS). During 2000 to 2004,
he was an Assistant Professor at Tohoku University with Masahiro Hirama (Sendai, Japan). He has also won several
postdoctoral fellowships to work at Parke-Davis (Cambridge, UK, 1996), ICSN-CNRS (Gif-sur-Yvette, France, 1997) and
Tohoku University (JSPS and CREST, 1997-2000). Dr. Lear is also a Co-founder and Director of a biotech company in
Singapore (biolynxtech.com).

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